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Voltage Gated Ion Channel Function: Gating, Conduction, And The Role Of Water And Protons, Alisher M. Kariev, Michael E. Green
Voltage Gated Ion Channel Function: Gating, Conduction, And The Role Of Water And Protons, Alisher M. Kariev, Michael E. Green
Publications and Research
Ion channels, which are found in every biological cell, regulate the concentration of electrolytes, and are responsible for multiple biological functions, including in particular the propagation of nerve impulses. The channels with the latter function are gated (opened) by a voltage signal, which allows Na+ into the cell and K+ out. These channels have several positively charged amino acids on a transmembrane domain of their voltage sensor, and it is generally considered, based primarily on two lines of experimental evidence, that these charges move with respect to the membrane to open the channel. At least three forms of motion, with …
A Swot Model Of The Challenges And Benefits Of Volunteer Involvement In Us Non-Profit Organisations During Times Of Fiscal Stress, Helisse Levine, Maria J. D’Agostino
A Swot Model Of The Challenges And Benefits Of Volunteer Involvement In Us Non-Profit Organisations During Times Of Fiscal Stress, Helisse Levine, Maria J. D’Agostino
Publications and Research
As a result of the current fiscal crisis, the US Federal Government is calling on non-profit organisations and communities across the country to contribute their service through volunteering. This study uses qualitative data retrieved from a purposive sample of New York City non-profit administrators to determine the challenges and benefits of volunteer involvement in US non-profit organisations during the economic downturn that began in 2008. Findings conclude that although US Federal Government initiatives, including $50 million of the American Recovery and Reinvestment Act allocated to the strengthening communities fund provided non-profits the opportunity to draw on an influx of a …
International Trade And The Ny/Nj Region: Will The Robust Recovery Weather 2011 Economic Shocks?, Eugene Spruck
International Trade And The Ny/Nj Region: Will The Robust Recovery Weather 2011 Economic Shocks?, Eugene Spruck
Publications and Research
In this paper, Eugene Spruck, a Weissman Center Fellow who served as the Chief Economist of the Port Authority of New York and New Jersey for more than a decade, reviews U.S. international trade and trade through the NY/NJ region in 2010 and takes a look at the risk factors for 2011. According to the paper, the value of U.S. international trade rebounded sharply in 2010 and is now only 6.2 percent below the peak realized in 2008 prior to the global recession. International trade to and from the United States totaled almost $3.2 trillion, a 20.9 percent increase compared …
Aligned Layers Of Silver Nano-Fibers, Andrii B. Golovin, Jeremy Stromer, Liubov Kreminska
Aligned Layers Of Silver Nano-Fibers, Andrii B. Golovin, Jeremy Stromer, Liubov Kreminska
Publications and Research
We describe a new dichroic polarizers made by ordering silver nano-fibers to aligned layers. The aligned layers consist of nano-fibers and self-assembled molecular aggregates of lyotropic liquid crystals. Unidirectional alignment of the layers is achieved by means of mechanical shearing. Aligned layers of silver nano-fibers are partially transparent to a linearly polarized electromagnetic radiation. The unidirectional alignment and density of the silver nano-fibers determine degree of polarization of transmitted light. The aligned layers of silver nano-fibers might be used in optics, microwave applications, and organic electronics.
Midgut And Fat Body Bacteriocytes In Neotropical Cerambycid Beetles (Coleoptera: Cerambycidae), Olga Calderon, Amy Berkov
Midgut And Fat Body Bacteriocytes In Neotropical Cerambycid Beetles (Coleoptera: Cerambycidae), Olga Calderon, Amy Berkov
Publications and Research
Xylophagous insects derive nutrients from intractable substrates by producing or ingesting cellulolytic enzymes, or by maintaining associations with symbiotic microbes. Wood-boring cerambycid beetle larvae sometimes house maternally-transmitted endosymbiotic yeasts that are presumed to provide their hosts with nutritional beneÞts. These are thought to be absent from species in the large subfamily Lamiinae; nevertheless yeasts have been repeatedly isolated from the guts of neotropical lamiines. The objective of this study was to conduct transmission electron microscopy (TEM) studies of cerambycid larval midgut tissues to determine if gut yeasts were intracellular, or simply present in the gut lumen. Nine cerambycid larvae were …
Pten Regulation Of Local And Long-Range Connections In Mouse Auditory Cortex, Qiaojie Xiong, Hysell V. Oviedo, Lloyd C. Trotman, Anthony M. Zador
Pten Regulation Of Local And Long-Range Connections In Mouse Auditory Cortex, Qiaojie Xiong, Hysell V. Oviedo, Lloyd C. Trotman, Anthony M. Zador
Publications and Research
Autism spectrum disorders (ASDs) are highly heritable developmental disorders caused by a heterogeneous collection of genetic lesions. Here we use a mouse model to study the effect on cortical connectivity of disrupting the ASD candidate gene PTEN (phosphatase and tensin homolog deleted on chromosome 10). Through Cre-mediated recombination, we conditionally knocked out PTEN expression in a subset of auditory cortical neurons. Analysis of long-range connectivity using channelrhodopsin-2 revealed that the strength of synaptic inputs from both the contralateral auditory cortex and from the thalamus onto PTEN-cko neurons was enhanced compared with nearby neurons with normal PTEN expression. Laser-scanning photostimulation showed …
Forgetting Act Up, Alexandra Juhasz
Protein-Dna Interactions Define The Mechanistic Aspects Of Circle Formation And Insertion Reactions In Is2 Transposition, Leslie A. Lewis, Mekbib Astatke, Peter T. Umekubo, Shaheen Alvi, Robert Saby, Jehan Afrose, Pedro H. Oliveira, Gabriel A. Monteiro, Duarte Mf Prazeres
Protein-Dna Interactions Define The Mechanistic Aspects Of Circle Formation And Insertion Reactions In Is2 Transposition, Leslie A. Lewis, Mekbib Astatke, Peter T. Umekubo, Shaheen Alvi, Robert Saby, Jehan Afrose, Pedro H. Oliveira, Gabriel A. Monteiro, Duarte Mf Prazeres
Publications and Research
Background Transposition in IS3, IS30, IS21 and IS256 insertion sequence (IS) families utilizes an unconventional two-step pathway. A figure-of-eight intermediate in Step I, from asymmetric single-strand cleavage and joining reactions, is converted into a double-stranded minicircle whose junction (the abutted left and right ends) is the substrate for symmetrical transesterification attacks on target DNA in Step II, suggesting intrinsically different synaptic complexes (SC) for each step. Transposases of these ISs bind poorly to cognate DNA and comparative biophysical analyses of SC I and SC II have proven elusive. We have prepared a native, soluble, active, GFP-tagged fusion derivative of the …
Maize Provitamin A Carotenoids, Current Resources, And Future Metabolic Engineering Challenges, Eleanore T. Wurtzel, Abby Cuttriss, Ratnakar Vallabhaneni
Maize Provitamin A Carotenoids, Current Resources, And Future Metabolic Engineering Challenges, Eleanore T. Wurtzel, Abby Cuttriss, Ratnakar Vallabhaneni
Publications and Research
Vitamin A deficiency is a serious global health problem that can be alleviated by improved nutrition. Development of cereal crops with increased provitamin A carotenoids can provide a sustainable solution to eliminating vitamin A deficiency worldwide. Maize is a model for cereals and a major staple carbohydrate source. Here, we discuss maize carotenogenesis with regard to pathway regulation, available resources, and current knowledge for improving carotenoid content and levels of provitamin A carotenoids in edible maize endosperm. This knowledge will be applied to improve the nutritional composition of related Poaceae crops. We discuss opportunities and challenges for optimizing provitamin A …
Horizontally-Aligned Carbon Nanotubes Arrays And Their Interactions With Liquid Crystal Molecules: Physical Characteristics And Display Applications, Frederick Roussel, Jean-Francois Brun, Alexandre Allart, Limin Huang, Stephen O'Brien
Horizontally-Aligned Carbon Nanotubes Arrays And Their Interactions With Liquid Crystal Molecules: Physical Characteristics And Display Applications, Frederick Roussel, Jean-Francois Brun, Alexandre Allart, Limin Huang, Stephen O'Brien
Publications and Research
We report on the physical characteristics of horizonthally-grown Single-Walled Carbon Nanotubes (h-al-SWNT) arrays and their potential use as transparent and conducting alignment layer for liquid crystals display devices. Microscopy (SEM and AFM), spectroscopic (Raman) and electrical investigations demonstrate the strong anisotropy of h-al-SWNT arrays. Optical measurements show that h-al-SWNTs are efficient alignment layers for Liquid Crystal (LC) molecules allowing the fabrication of optical wave plates. Interactions between h-al-SWNT arrays and LC molecules are also investigated evidencing the weak azimuthal anchoring energy at the interface, which, in turn, leads to LC devices with a high pretilt angle. The electro-optical reponses of …
Evidence For A Grooming Claw In A North American Adapiform Primate: Implications For Anthropoid Origins, Stephanie Maiolino, Doug M. Boyer, Jonathan I. Bloch, Christopher C. Gilbert, Joseph Groenke
Evidence For A Grooming Claw In A North American Adapiform Primate: Implications For Anthropoid Origins, Stephanie Maiolino, Doug M. Boyer, Jonathan I. Bloch, Christopher C. Gilbert, Joseph Groenke
Publications and Research
Among fossil primates, the Eocene adapiforms have been suggested as the closest relatives of living anthropoids (monkeys, apes, and humans). Central to this argument is the form of the second pedal digit. Extant strepsirrhines and tarsiers possess a grooming claw on this digit, while most anthropoids have a nail. While controversial, the possible presence of a nail in certain European adapiforms has been considered evidence for anthropoid affinities. Skeletons preserved well enough to test this idea have been lacking for North American adapiforms. Here, we document and quantitatively analyze, for the first time, a dentally associated skeleton of Notharctus tenebrosus …
Serotonin 1a Receptor-Mediated Signaling Through Erk And Pkcα Is Essential For Normal Synaptogenesis In Neonatal Mouse Hippocampus, A. Mogha, Sara R. Guariglia, Priya Ranjan Debata, Guang Y. Wen, Probal Banerjee
Serotonin 1a Receptor-Mediated Signaling Through Erk And Pkcα Is Essential For Normal Synaptogenesis In Neonatal Mouse Hippocampus, A. Mogha, Sara R. Guariglia, Priya Ranjan Debata, Guang Y. Wen, Probal Banerjee
Publications and Research
Aberrant expression of the presynaptic serotonin 1A receptor (5-HT1A-R) because of a polymorphism in the 5-HT1A-R gene is associated with severe depression in human, whereas its absence up to postnatal day 21 (P21) in the forebrain of mice results in heightened anxiety in adulthood. These observations collectively indicate that the 5-HT1A-R has a crucial role in brain development. To understand the mechanistic underpinnings of this phenomenon, we used organotypic slice cultures of hippocampi from C57BL6 mice (C57) at P15, which coincides with the peak of neonatal synaptogenesis. Stimulation of the hippocampal 5-HT1A-R caused a dramatic increase …
Relationships Between Urinary Biomarkers Of Phytoestrogens, Phthalates, Phenols, And Pubertal Stages In Girls, Tandra R. Chakraborty, Eilliut Alicea, Sanjoy Chakraborty
Relationships Between Urinary Biomarkers Of Phytoestrogens, Phthalates, Phenols, And Pubertal Stages In Girls, Tandra R. Chakraborty, Eilliut Alicea, Sanjoy Chakraborty
Publications and Research
Phytoestrogens, phthalates, and phenols are estrogen-disrupting chemicals that have a pronounced effect at puberty. They are exogenous chemicals that are either plant-derived or man-made, and can alter the functions of the endocrine system and cause various health defects by interfering with the synthesis, metabolism, binding, or cellular responses of natural estrogens. Phytoestrogens, phthalates, and phenols are some of the potent estrogens detectable in urine. Phytoestrogens are plant-derived xenestrogens found in a wide variety of food products, like soy-based food, beverages, several fruits, and vegetables. Exposure to phytoestrogens can delay breast development and further lead to precocious puberty. The effect of …
Picturing The Wake: Arcimboldo, Joyce And His ‘Monster,’, Václav Paris
Picturing The Wake: Arcimboldo, Joyce And His ‘Monster,’, Václav Paris
Publications and Research
This essay considers Finnegans Wake through the lens of Arcimboldo's art. Drawing on surrealism, French theory, and close readings of parts of Joyce's most difficult book, it shows the work to be visually richer and stranger than we imagined.
Palatalization In Romanian — Acoustic Properties And Perception, Laura Spinu, Irene Vogel, H. Timothy Bunnell
Palatalization In Romanian — Acoustic Properties And Perception, Laura Spinu, Irene Vogel, H. Timothy Bunnell
Publications and Research
This paper presents the results of an acoustic study of fricatives from four places of articulation produced by 31 native speakers of Romanian, as well as those of a perceptual study using the stimuli from the acoustic experiment, allowing for a direct comparison between acoustic properties and perception. It was found that there are greater acoustic differences between plain and palatalized labials and dorsals as compared to coronals. The acoustic results were paralleled by the perceptual findings. This pattern departs from cross-linguistic generalizations made with respect to the properties of secondary palatalization. A likely source of the differences is the …
Preempting Jury Challenges: Strategies For Courts And Jury System Administrators, Nina Chernoff, Joseph Kadane
Preempting Jury Challenges: Strategies For Courts And Jury System Administrators, Nina Chernoff, Joseph Kadane
Publications and Research
No abstract provided.
Navigating The High Seas: Why The U.S. Should Ratify The Law Of The Sea Treaty, Rebecca Bratspies
Navigating The High Seas: Why The U.S. Should Ratify The Law Of The Sea Treaty, Rebecca Bratspies
Publications and Research
No abstract provided.
Protecting The Freedom Of Information Act Requestor: Privacy For Information Seekers, Sarah Lamdan
Protecting The Freedom Of Information Act Requestor: Privacy For Information Seekers, Sarah Lamdan
Publications and Research
No abstract provided.
Notes On The Diet Of The Malay Civet (Viverra Tangalunga) And Other Civets In Logged And Unlogged Lowland Dipterocarp Rain Forests In Sabah, Borneo, Christina P. Colon, John B. Sugau
Notes On The Diet Of The Malay Civet (Viverra Tangalunga) And Other Civets In Logged And Unlogged Lowland Dipterocarp Rain Forests In Sabah, Borneo, Christina P. Colon, John B. Sugau
Publications and Research
Civet diets were examined in a logged and unlogged Bornean rain forest. Malay civets (Viverra tangalunga) consumed invertebrates, fruit, rodents, insectivores, birds, snakes and lizards, and appear to show preference for centipedes and scorpions. Other civet species consumed fruit, such as figs, Connarus sp. and Annona sp., particularly in the unlogged forest, but also consumed invertebrates and vertebrates. Reduced fruit consumption observed in the logged forest may be due to lower availability and may be offset by increased consumption of invertebrates. The increased overlap in diet between Malay civets and other civets in disturbed areas may lead to …
Siue Students Visit Joplin One Year Later, Aldemaro Romero Jr.
Siue Students Visit Joplin One Year Later, Aldemaro Romero Jr.
Publications and Research
No abstract provided.
Zamora Discusses Secrets Of Graphic Designers, Aldemaro Romero Jr.
Zamora Discusses Secrets Of Graphic Designers, Aldemaro Romero Jr.
Publications and Research
No abstract provided.
Human Rights And Environmental Regulation, Rebecca Bratspies
Human Rights And Environmental Regulation, Rebecca Bratspies
Publications and Research
No abstract provided.
Diversity Dialogues: Dealing With Stress, Raquel Gabriel
Diversity Dialogues: Dealing With Stress, Raquel Gabriel
Publications and Research
No abstract provided.
Wrong About The Right: How Courts Undermine The Fair Cross-Section Guarantee By Confusing It With Equal Protection, Nina Chernoff
Wrong About The Right: How Courts Undermine The Fair Cross-Section Guarantee By Confusing It With Equal Protection, Nina Chernoff
Publications and Research
No abstract provided.
Using A Narrative Lens To Understand Empathy And How It Matters In Judging, Andrea Mcardle
Using A Narrative Lens To Understand Empathy And How It Matters In Judging, Andrea Mcardle
Publications and Research
No abstract provided.
Marital Status And Sexual Orientation Discrimination In Infertility Care, Richard Storrow
Marital Status And Sexual Orientation Discrimination In Infertility Care, Richard Storrow
Publications and Research
No abstract provided.
"The Phantom Children Of The Republic": International Surrogacy And The New Illegitimacy, Richard Storrow
"The Phantom Children Of The Republic": International Surrogacy And The New Illegitimacy, Richard Storrow
Publications and Research
No abstract provided.
Rachilde, Marguerite Eymery Vallette (1860-1953), Ria Banerjee
Rachilde, Marguerite Eymery Vallette (1860-1953), Ria Banerjee
Publications and Research
This is a biographical overview of the life and principle works of the French author Rachilde, a.k.a. Marguerite Eymery Vallette (1860-1953), one of the few women writers working in the masculinist field of fin-de-siecle or decadent fiction.
An Assessment Of Strategies For Choosing Between Competitive Marketplaces, Tim Miller, Jinzhong Niu
An Assessment Of Strategies For Choosing Between Competitive Marketplaces, Tim Miller, Jinzhong Niu
Publications and Research
Traders that operate in markets with multiple competing marketplaces must often choose with which marketplace they will trade. These choices encourage marketplaces to seek competitive advantages against each other by adjusting various parameters, such as the price they charge, or how they match buyers and sellers. Traders can take advantage of this competition to improve utility. However, appropriate strategies must be used to decide with which marketplace a trader should shout. In this paper, we assess several different solutions to the problem of marketplace selection by running simulations of double auctions using the JCAT platform. The parameter spaces of these …
Lavallee Teaches And Studies Chinese Culture, Aldemaro Romero Jr.
Lavallee Teaches And Studies Chinese Culture, Aldemaro Romero Jr.
Publications and Research
No abstract provided.