Digital Commons Network^™

A Primer For Mathematical Modeling, Marla A. Sole

Publications and Research

With the implementation of the National Council of Teachers of Mathematics recommendations and the adoption of the Common Core State Standards for Mathematics, modeling has moved to the forefront of K-12 education. Modeling activities not only reinforce purposeful problem-solving skills, they also connect the mathematics students learn in school with the mathematics they will use outside of school. Instructors have found mathematical modeling difficult to teach. To successfully incorporate modeling activities I believe that curricular changes should be accompanied by professional development for curriculum developers, classroom teachers, and higher education professionals. This article serves as an introduction to modeling by …

Linux For Academics, Part I, Steven Ovadia

Publications and Research

The article focuses on GNU/Linux, an open-source operating system based on Unix. Linux offers more choice and control to academic users. The article encourages academic users to explore Linux as a way to be more productive.

The American Association Of School Librarians (Aasl) Standards For The 21st Century Learner Lesson Plan Database, Christina Miller

Publications and Research

The American Association of School Librarians (AASL) Standards for the 21st Century Learner Lesson Plan Database (AASL Database) is a free, Open Access, interactive tool recently (2011) developed by the American Association of School Librarians, a division of the American Library Association, to assist librarians, teachers and other educators in implementing the AASL Standards for the 21st Century Learner (AASL Standards) and the Common Core State Standards. It is comprised of vetted, content-area lesson plans meant to provide excellent models to integrate AASL Standards across K-12 curricula; the platform also includes social networking features and a user portfolio. The AASL …

The Queer Dialectic Of Whitman’S Nation: "Let" In “Respondez”, Václav Paris

Publications and Research

This article considers Whitman's "Respondez" - perhaps his strangest poem. It seeks to explicate the poem by looking at his shifting use of the word "let." The article draws on studies of queer theory, nationalism, modernism, to reveal an unfamiliar and far more radical Whitman than we are familiar with.

Synesthesia: A Colorful Word With A Touching Sound?, Myrto I. Mylopoulos, Tony Ro

Publications and Research

Synesthesia is a fairly common condition in which individuals experience atypical responses (such as color experiences) in association with certain types of stimuli (such as non-colored letters). Although synesthesia has been described for centuries, only very recently has there been an explosive growth of systematic scientific examinations of this condition. In this article, we review and critically evaluate current methods for both assessing synesthesia and examining its psychological basis, including the “test-retest” procedure, online battery assessments, and behavioral experiments. We highlight the limitations of these methods for understanding the nature of this complex condition and propose potential solutions to address …

Le Nature Degli American Studies, Cindi Katz

Publications and Research

Al “Futures of American Studies Institute” di Dartmouth del 2003 lanciai una provocazione sulle “geografie immaginate” dell’americanistica. Volevo mettere in discussione sia le celebrazioni romantiche del “luogo” in quanto elemento in qualche modo autentico e particolare, minacciato da un mondo sempre più globalizzato e controllato dalle multinazionali, sia l’esaltazione della “delocalizzazione” nelle società in rete, negli “spazi di flusso”, nella mobilità senza attrito. Suggerivo che queste, come altre geografie poco studiate, si sposano troppo facilmente con molte correnti dell’eccezionalismo americano.

Uncreative Influence: Louis Aragon’S Paysan De Paris And Walter Benjamin’S Passagen-Werk, Václav Paris

Publications and Research

This paper looks at the role Louis Aragon’s 1926 novel Paris Peasant played in the composition of Walter Benjamin’s Arcades Project. How we might theorize the literary appeal of the Arcades Project, as evidenced in contemporary poetry and visual art; and, more broadly, what is the relation between the aesthetics and the philosophy or politics in Benjamin’s text? The model I propose is one of a Bloomian “anxiety of influence.” By looking at Benjamin’s earlier writings and his correspondence with Theodor Adorno and Gershom Scholem, we see not only that Benjamin’s work shared much with Aragon’s brand of Surrealism, but …

Speaking As One: Supporting Open Access With Departmental Resolutions, Madeline Cohen, Maura A. Smale, Jill Cirasella, Cynthia Tobar, Jessie Daniels

Publications and Research

Library faculty at the City University of New York (CUNY) have engaged in promoting and advocating for open access publishing at each of our campuses as well as across the University. Inspired by the passing of a faculty senate resolution in support of the creation of an open access institutional repository and associated policies, many CUNY librarians felt the need to raise their level of commitment. In this article, the authors—four library faculty members and one faculty member from outside the library—share their experiences creating and approving open access policies in the library departments of four CUNY schools and promoting …

Intimate Partner Violence During Pregnancy: Victim Or Perpetrator? Does It Make A Difference?, Yuliya Shneyderman, Michele Kiely

Publications and Research

Objectives: To differentiate between forms of intimate partner violence (IPV)(victim only, perpetrator only, or participating in reciprocal violence) and examine risk profiles and pregnancy outcomes.

Design: Prospective

Setting: Washington, DC, July 2001 to October 2003

Sample: 1044 high-risk African-American pregnant women who participated in a randomized controlled trial to address IPV, depression, smoking, and environmental tobacco smoke exposure.

Methods: Multivariable linear and logistic regression

Main outcome measures: Low and very low birth weight, preterm and very preterm birth

Results: 5% of women were victims only, 12% were perpetrators only, 27% participated in reciprocal violence, and 55% reported no IPV. …

Sequential Screening For Psychosocial And Behavioural Risk During Pregnancy In A Population Of Urban African Americans, Michele Kiely, Marie G. Gantz, M. Nabil El-Khorazaty, Ayman El-Mohandes

Publications and Research

Objective: Screening for psychosocial and behavioral risks, such as depression, intimate partner violence and smoking, during pregnancy is considered state-of-the-art in prenatal care (PNC). This prospective longitudinal analysis examines the added benefit of repeated screening over a one-time screen in identifying such risks during pregnancy.

Design: Data were collected as part of a randomized controlled trial to address intimate partner violence (IPV), depression, smoking and environmental tobacco smoke exposure (ETSE) in African-Americans women.

Setting: PNC sites in the District of Columbia serving mainly minority women

Population: 1044 African-American pregnant women in the District of Columbia

Methods: Mothers were classified by …

Queer Pedagogical Desire: A Study Guide, Matt Brim

Publications and Research

This essay explores the queer pedagogical desires that attended my writing of the Study Guide for the documentary film United in Anger: A History of ACT UP (Jim Hubbard, 2012). The analysis takes up Robyn Wiegman’s central question in Object Lessons, “What is it we expect our relationship to our objects of study to do?”, which is of particular importance to the discipline of queer studies insofar as the field is oriented around the desire to meld social justice with critical pedagogy. The queer professor’s desire in the case of the Study Guide-as-object was to create a text that …

Fmri Of Working Memory Impairment After Recovery From Subarachnoid Hemorrhage, Timothy M. Ellmore, Fiona Rohlffs, Faraz Khursheed

Publications and Research

Recovery from aneurysmal subarachnoid hemorrhage (SAH) is often incomplete and accompanied by subtle but persistent cognitive deficits. Previous neuropsychological reports indicate these deficits include most prominently memory impairment, with working memory particularly affected. The neural basis of these memory deficits remains unknown and unexplored by functional magnetic resonance imaging (fMRI). In the present study, patients who experienced (SAH) underwent fMRI during the performance of a verbal working memory paradigm. Behavioral results indicated a subtle but statistically significant impairment relative to healthy subjects in working memory performance accuracy, which was accompanied by relatively increased blood-oxygen level dependent signal in widespread left …

Situational Awareness: Reframing Within Fire Service Culture, Martha Dow, Len Garis, Larry Thomas

Publications and Research

There is increasing attention being paid to better understanding and consequently decreasing the incidence of on-the-job injuries and deaths within the fire service across North America. Heightening situational awareness is being explored as the most critical factor in maintaining the safety of participants in high risk, low frequency events. Situational awareness is generally defined as “understanding the current environment and being able to accurately anticipate future problems to enable effective action”. Situational awareness is cited as a critical factor in most research exploring safety in fire suppression activities and in many cases the “No. 1 factor identified by firefighters filing …

Womb Envy: Jean-Luc Godard's Breathless, A Woman Is A Woman, And Hail Mary, Caroline Rupprecht, Caroline Rupprecht

Publications and Research

No abstract provided.

Mission Work, Conversion, And The Italian Immigrant In Turn-Of-The-Century New York City, Alexandra A. De Luise

Publications and Research

Anson Phelps Stokes Italian Free Library was an example of an ethnic library located in an Italian enclave of New York City in the 1890s to 1910s. It served a need in helping educate and Americanize Italians living in that area, while also indoctrinating them into Protestant faith by its library director, Pastor Antonio Arrighi.

Global Trends In Seasonality Of Normalized Difference Vegetation Index (Ndvi), 1982–2011, J. Ronald Eastman, Florencia Sangermano, Elia Axinia Machado, John Rogan, Assaf Anyamba

Publications and Research

A 30-year series of global monthly Normalized Difference Vegetation Index (NDVI) imagery derived from the Global Inventory Modeling and Mapping Studies (GIMMS) NDVI3g archive was analyzed for the presence of trends in changing seasonality. Using the Seasonal Trend Analysis (STA) procedure, over half (56.30%) of land surfaces were found to exhibit significant trends. Almost half (46.10%) of the significant trends belonged to three classes of seasonal trends (or changes). Class 1 consisted of areas that experienced a uniform increase in NDVI throughout the year, and was primarily associated with forested areas, particularly broadleaf forests. Class 2 consisted of areas experiencing …

Dosage Considerations For Transcranial Direct Current Stimulation In Children: A Computational Modeling Study, Sudha Kilaru Kessler, Preet Minhas, Adam J. Woods, Alyssa Rosen, Casey Gorman, Marom Bikson

Publications and Research

Transcranial direct current stimulation (tDCS) is being widely investigated in adults as a therapeutic modality for brain disorders involving abnormal cortical excitability or disordered network activity. Interest is also growing in studying tDCS in children. Limited empirical studies in children suggest that tDCS is well tolerated and may have a similar safety profile as in adults. However, in electrotherapy as in pharmacotherapy, dose selection in children requires special attention, and simple extrapolation from adult studies may be inadequate. Critical aspects of dose adjustment include 1) differences in neurophysiology and disease, and 2) variation in brain electric fields for a specified …

It’S Time To Fear! Interval Timing In Odor Fear Conditioning In Rats, Kiseko Shionoya, Chloé Hegoburu, Bruce L. Brown, Regina M. Sullivan, Valérie Doyère, Anne-Marie Mouly

Publications and Research

Time perception is crucial to goal attainment in humans and other animals, and interval timing also guides fundamental animal behaviors. Accumulating evidence has made it clear that in associative learning, temporal relations between events are encoded, and a few studies suggest this temporal learning occurs very rapidly. Most of these studies, however, have used methodologies that do not permit investigating the emergence of this temporal learning. In the present study we monitored respiration, ultrasonic vocalization (USV) and freezing behavior in rats in order to perform fine-grain analysis of fear responses during odor fear conditioning. In this paradigm an initially neutral …

Fast Quantitative Real-Time Pcr-Based Screening For Common Chromosomal Aneuploidies In Mouse Embryonic Stem Cells, Charlotte D'Hulst, Irena Parvanova, Delia Tomoiaga, Maria L. Sapar, Paul Feinstein

Publications and Research

Chromosomal integrity has been known for many years to affect the ability of mouse embryonic stem cells (mESCs) to contribute to the germline of chimeric mice. Abnormal chromosomes are generally detected by standard cytogenetic karyotyping. However, this method is expensive, time consuming, and often omitted prior to blastocyst injection, consequently reducing the frequency of mESC-derived offspring. Here, we show a fast, accurate, and inexpensive screen for identifying the two most common aneuploidies (Trisomy 8 and loss of chromosome Y) in genetically manipulated mESCs using quantitative real-time PCR (qPCR). Screening against these two aneuploidies significantly increases the fraction of normal mESC …

Modified Impact Of Emotion On Temporal Discrimination In A Transgenic Rat Model Of Huntington Disease, Alexis Faure, Mouna Es-Sesddiqi, Bruce L. Brown, Hoa P. Nguyen, Olaf Riess, Stephan Von Hörsten, Pascale Le Blanc, Nathalie Desvignes, Bruno Bozon, Nicole El Massioui, Valérie Doyère

Publications and Research

Huntington's disease (HD) is characterized by triad of motor, cognitive, and emotional symptoms along with neuropathology in fronto-striatal circuit and limbic system including amygdala. Emotional alterations, which have a negative impact on patient well-being, represent some of the earliest symptoms of HD and might be related to the onset of the neurodegenerative process. In the transgenic rat model (tgHD rats), evidence suggest emotional alterations at the symptomatic stage along with neuropathology of the central nucleus of amygdala (CE). Studies in humans and animals demonstrate that emotion can modulate time perception. The impact of emotion on time perception has never been …

From Tweet To Blog Post To Peer-Reviewed Article: How To Be A Scholar Now, Jessie Daniels

Publications and Research

Digital media is changing how scholars interact, collaborate, write and publish. This piece describes how to be a scholar now, when peer-reviewed articles can begin as Tweets and blog posts. In this new environment, scholars are able to create knowledge in ways that are more open, more fluid, and more easily read by wider audiences.

A Novel Subnetwork Alignment Approach Predicts New Components Of The Cell Cycle Regulatory Apparatus In Plasmodium Falciparum, Hong Cai, Changjin Hong, Timothy G. Lilburn, Armando L. Rodriguez, Sheng Chen, Jianying Gu, Rui Kuang, Yufeng Wang

Publications and Research

Background According to the World Health organization, half the world's population is at risk of contracting malaria. They estimated that in 2010 there were 219 million cases of malaria, resulting in 660,000 deaths and an enormous economic burden on the countries where malaria is endemic. The adoption of various high-throughput genomics-based techniques by malaria researchers has meant that new avenues to the study of this disease are being explored and new targets for controlling the disease are being developed. Here, we apply a novel neighborhood subnetwork alignment approach to identify the interacting elements that help regulate the cell cycle of …

Β2 Adrenergic Receptor Fluorescent Protein Fusions Traffic To The Plasma Membrane And Retain Functionality, Jaclyn Bubnell, Patrick Pfister, Maria L. Sapar, Matthew E. Rogers, Paul Feinstein

Publications and Research

Green fluorescent protein (GFP) has proven useful for the study of protein interactions and dynamics for the last twenty years. A variety of new fluorescent proteins have been developed that expand the use of available excitation spectra. We have undertaken an analysis of seven of the most useful fluorescent proteins (XFPs), Cerulean (and mCerulean3), Teal, GFP, Venus, mCherry and TagRFP657, as fusions to the archetypal G-protein coupled receptor, the β2 adrenergic receptor (β2AR). We have characterized these β2AR::XFP fusions in respect to membrane trafficking and G-protein activation. We noticed that in the mouse neural cell line, OP 6, that membrane …

Lipid Metabolites Enhance Secretion Acting On Snare Microdomains And Altering The Extent And Kinetics Of Single Release Events In Bovine Adrenal Chromaffin Cells, Virginia García-Martínez, José Villanueva, Cristina J. Torregrosa-Hetland, Robert Bittman, Ashlee Higdon, Victor M. Darley-Usmar, Bazbek Davletov, Luis M. Gutiérrez

Publications and Research

Lipid molecules such as arachidonic acid (AA) and sphingolipid metabolites have been implicated in modulation of neuronal and endocrine secretion. Here we compare the effects of these lipids on secretion from cultured bovine chromaffin cells. First, we demonstrate that exogenous sphingosine and AA interact with the secretory apparatus as confirmed by FRET experiments. Examination of plasma membrane SNARE microdomains and chromaffin granule dynamics using total internal reflection fluorescent microscopy (TIRFM) suggests that sphingosine production promotes granule tethering while arachidonic acid promotes full docking. Our analysis of single granule release kinetics by amperometry demonstrated that both sphingomyelinase and AA treatments enhanced …

Assessing The Burden Of Crime And The Criminal Sanction: A Public Health Perspective On Critical Issues In Criminal Justice, Jeremy Travis

Publications and Research

No abstract provided.

Differential Joint-Specific Corticospinal Tract Projections Within The Cervical Enlargement, Curtis O. Asante, John H. Martin

Publications and Research

The motor cortex represents muscle and joint control and projects to spinal cord interneurons and–in many primates, including humans–motoneurons, via the corticospinal tract (CST). To examine these spinal CST anatomical mechanisms, we determined if motor cortex sites controlling individual forelimb joints project differentially to distinct cervical spinal cord territories, defined regionally and by the locations of putative last-order interneurons that were transneuronally labeled by intramuscular injection of pseudorabies virus. Motor cortex joint-specific sites were identified using intracorticalmicrostimulation. CST segmental termination fields from joint-specific sites, determined using anterograde tracers, comprised a high density core of terminations that was consistent between animals …

Cholinergic Enhancement Of Brain Activation In Mild Cognitive Impairment During Episodic Memory Encoding, Shannon L. Risacher, Yang Wang, Heather A. Wishart, Laura A. Rabin, Laura A. Flashman, Brenna C. Mcdonald, John D. West, Robert B. Santulli, Andrew J. Saykin

Publications and Research

Objective: To determine the physiological impact of treatment with donepezil (Aricept) on neural circuitry supporting episodic memory encoding in patients with amnestic mild cognitive impairment (MCI) using functional magnetic resonance imaging (fMRI).

Methods: Eighteen patients with MCI and 20 age-matched healthy controls (HC) were scanned twice while performing an event-related verbal episodic encoding task. MCI participants were scanned before treatment and after approximately 3 months on donepezil; HCwere untreated but rescanned at the same interval.Voxel-level analyses assessed treatment effects on activation profiles in MCI patients relative to retest changes in non-treated HC. Changes in task-related connectivity in medial temporal circuitry …

Specificity In The Actions Of The Ubr1 Ubiquitin Ligase In The Degradation Of Nuclear Receptors☆, Rasheda Sultana, Maria A. Theodoraki, Avrom J. Caplan

Publications and Research

The UBR1 ubiquitin ligase promotes degradation of proteins via the N-end rule and by another mechanism that detects a misfolded conformation. Although UBR1 was shown recently to act on protein kinases whose misfolding was promoted by inhibition of Hsp90, it was unknown whether this ubiquitin ligase targeted other client types of the chaperone. We analyzed the role of UBR1 in the degradation of nuclear receptors that are classical clients of Hsp90. Our results showed that UBR1 deletion results in impaired degradation of the glucocorticoid receptor and the androgen receptor but not the estrogen receptor α. These findings demonstrate specificity in …

Students' Immersion Experiences In Study Abroad, Federica Goldoni

Publications and Research

Data show that a larger number of students than ever are participating in learning experiences abroad. However, such programs are not always as immersive and intensive as participants, faculty, program directors, and administrators would wish. This study examines the ways in which students created sustained opportunities to interact with members of the host community as well as episodes of cultural clash, miscommunication, and misunderstanding experienced at the intersection of two cultures that led to diminishing willingness to interact with members of the host community. The article concludes with recommendations for pre-departure experiences that are designed to help students become more …

Wave Function For Time-Dependent Harmonically Confined Electrons In A Time-Dependent Electric Field, Yu-Qi Li, Xiao-Yin Pan, Viraht Sahni

Publications and Research

The many-body wave function of a system of interacting particles confined by a time-dependent harmonic potential and perturbed by a time-dependent spatially homogeneous electric field is derived via the Feynman path-integral method. The wave function is comprised of a phase factor times the solution to the unperturbed time-dependent Schrödinger equation with the latter being translated by a time-dependent value that satisfies the classical driven equation of motion. The wave function reduces to that of the Harmonic Potential Theorem wave function for the case of the time-independent harmonic confining potential.