Digital Commons Network^™

On Jamming: ‘Study’ And The Unstudied, Stefano Morello

Publications and Research

No abstract provided.

Spinal Matrix Metalloproteinase 8 Regulates Pain After Peripheral Trauma, Maral Tajerian, J. David Clark

Publications and Research

It is well documented that pain chronification requires a host of plastic mechanisms at the spinal cord (SC) level, including alterations in neuronal and glial structure and function. Such cellular plasticity necessitates the existence of a plastic extracellular matrix(ECM). Here, we describe a key role for ECM remodeling in the regulation of chronic pain following peripheral injury. Three weeks following tibia fracture in mice, we show increased levels of MMP8 in the SC. Furthermore, we show that the pharmacological or genetic downregulation of MMP8 ameliorates the pain phenotype observed after injury. These results delineate an extracellular mechanism for pain chronification, …

Identifying E-Books Authored By Faculty: A Method For Scoping The Digital Collection And Curating A List, Sonali Sugrim, Laura Schimming, Gali Halevi

Publications and Research

Electronic books are a substantial component of many academic libraries. Many libraries aim to make their collections easily discoverable through curated lists. The authors’ library devised a methodology to identify and flag all e-books authored by our institution’s faculty using MARCEdit and Microsoft Access. We highlight some of the challenges in gathering a comprehensive list of titles, the process of formulating such a list, and the measures needed to actively curate e-books by faculty for both content already in the collection and newly published titles.

Developing A Culturally Responsive Assessment Model For Short-Term Study Abroad At An Urban Community College, Grace Pai, Katie Wilson

Publications and Research

The literature on assessing education abroad is dominated by studies using pre-/post-survey instruments to measure student growth across broad dimensions like global perspectives or intercultural competencies. Most studies also focus on study abroad programs in private, four-year or graduate schools. There is limited research assessing programs in community colleges serving underrepresented students, despite the increasing diversity of education abroad participants. This article addresses that gap, and even more important, illustrates the process of how an urban, Minority Serving Institution-designated community college designed a culturally responsive assessment framework—one that that combines quantitative analysis of surveys with qualitative analysis of student e-Portfolios— …

Debating Ethnic Governance In China, Yan Sun

Publications and Research

Previous scholarship has identified an emerging consensus for ethnic policy reform in China, in the direction of strengthening national integration and a ‘melting pot.’ This article identifies three major contending schools in Chinese debates about the country’s ethnic governance: liberal autonomists, integrationists and socialist autonomists. It argues that the socialist autonomists, who oppose the ‘melting pot,’ have prevailed politically. Contention among the three schools, specifically, revolves around tradeoffs between autonomy and ethnic particularism. That is, compromised autonomy but preferential policies. The liberal autonomists reject the tradeoffs because of the cost to autonomy. The integrationists reject the tradeoffs because of the …

Introduction: Connecting Histories: Jews And Their Others In Early Modern Europe, Francesca Bregoli

Publications and Research

Introduction to edited volume Connecting Histories: Jews and Their Others in Early Modern Europe (ed. by Francesca Bregoli and David B. Ruderman)

Does Widowhood Affect Cognitive Function Among Chinese Older Adults?, Zhenmei Zhang, Lydia W. Li, Hongwei Xu, Jinyu Liu

Publications and Research

There is growing evidence from Western countries that widowhood may affect cognitive health in later life. However, little is known about whether widowhood isassociated with cognitive health in Eastern Asian countries such as China and what factors may explain the association between widowhood and cognitive health. Weadd to this line of research by investigating the effect of widowhood on 2-year change in cognitive function among Chinese adults ages 55 and older from 2011 to2013, using data from the China Health and Retirement Longitudinal Study. Cognitive function was measured by episodic memory and mental intactness (i.e.,attention and time orientation). Our results …

Do Readers Judge Books By Author Gender? Results From A Randomized Experiment, Adam Kapelner, Dana B. Weinberg

Publications and Research

We run a randomized experiment to examine gender discrimination in book purchasing with 2,544 subjects on Amazon’s Mechanical Turk. We manipulate author gender and book genre in a factorial design to study consumer preferences for male versus female versus androgynous authorship. Despite previous findings in the literature showing gender discrimination in book publishing and in evaluations of work, respondents expressed no gender preference across a variety of measures, including quality, interest, and the amount they were willing to pay to purchase the book. This nonfinding, if it holds up to additional research, suggests that book consumers may not express the …

Scalar Transport Over A Forest Edge With Impact Of Vertical Distribution Of Foliage And Source Types, Yulong Ma, Heping Liu, Zhenqing Liu, Chuixiang Yi, Brian Lamb

Publications and Research

The dynamics of forest-boundary-layer interactions over a forest edge have been an interesting research topic in recent years. A better understanding of edge flow has implications for the siting and interpretation of flux measurements near a forest edge. In the present study, we use large-eddy simulations with the newly developed multi-layer canopy model MCANOPY to investigate canopy flows, or more specifically scalar transfer, over a forest edge. Two important impact factors for edge flows are considered: the vertical distribution of foliage and the scalar source/sink distribution. The simulations show that both factors have non-ignored impacts on the scalar transfer over …

Episodic And Continuous Recharge Estimation From High-Resolution Well Records, Timothy Eaton

Publications and Research

Water table fluctuation (WTF) methods are a primary and well-established way to determine groundwater recharge based on the direct response of the water table to precipitation input. An emerging complexity of recharge is whether it occurs as an episodic and transient process, or a continuous steady-state process, however most studies have not focused on these short-term vs long-term timescales, in part because of a lack of data resolution. Here, high-resolution (subhourly) precipitation and water level data are analyzed for wells in the suburbs of New York City using two contrasting WTF approaches, with a common mathematical basis, that are suited …

Defining Translinguality, Sara P. Alvarez, Bruce Horner

Publications and Research

This article reviews the history of conflicting meanings for translinguality in composition studies, locating that history in the context of other competing terms for language difference with which translinguality is sometimes affiliated and competes, and conflicting definitions of these, and in the context of perceived changes to global communication technologies and migration patterns. It argues for approaching translinguality and the confusion surrounding it as evidence of an epistemological break and explains confusions as a response to the challenges such a break poses. It demonstrates the residual operation of monolingualist notions of language in arguments for “code-meshing,” “plurilinguality,” and “translanguaging” and …

Crossing Borders In Business And Economics Classrooms: Implementing Telecollaboration To Advance Diversity And 21st Century Skills, Marta Fondo, Schiro Withanachchi

Publications and Research

The emerging changes in global societies challenge businesses as teams work across borders. Consequently, higher education promotes student interaction from diverse cultural backgrounds using technological tools without restricting time, cost, motivation or mobility. In this regard, telecollaboration engages students in a learning process that develops 21st century skills with peers from diverse language, socio-cultural, and educational backgrounds. This article presents a telecollaboration project designed and implemented by Queens College, City University of New York, and Universitat Oberta de Catalunya, an online university in Barcelona, in which 196 Economics and Business undergraduate students from the United States and Mexico enhanced intercultural …

Using Fan Studies To Put Information Literacy In Context: On Teaching A Credit Course With A Theme, Nancy M. Foasberg

Publications and Research

No abstract provided.

Public Land Revisited: Municipalization And Privatization In Newark And New York City, Samuel Stein, Oksana Mironova

Publications and Research

Public land plays a central role in contemporary urban planning struggles. Using a comparative case study approach focused on the north-eastern US cities of Newark and New York City, we uncover patterns of land acquisition and dispossession that fit five broad and often overlapping periods in planning history: City Beautiful, metropolitan reorganization, deindustrialization, and devaluation, followed by hyper-commodification in New York City and redevelopment amidst disinvestment in Newark. Through this periodization, we find that accumulation and alienation of urban public land has largely taken place through two modes of municipalization (targeted and reactive) and two modes of privatization (community-led and …

Enabling Precision Medicine Via Standard Communication Of Hts Provenance, Analysis, And Results, Gil Alterovitz, Dennis Dean, Carole Globe, Michael R. Crusoe, Stiam Soiland-Reyes, Amanda Bell, Anais Hayes, Anita Suresh, Anjan Purkkayastha, Charles H. King, Dan Taylor, Elaine Johanson, Elaine E. Thompson, Eric Donaldson, Hiroki Morizono, Hsinyi Tsang, Jeet K. Vora, Jeremy Goecks, Jianchao Yao, Jonas S. Almeida, Jonathon Keeney, Kanakadurga Addepalli, Konstantinos Krampis, Krista M. Smith, Lydia Guo, Mark Walderhaug, Marco Schito, Matthew Ezewudo, Nuria Guimera, Paul Walsh, Robel Kahsay, Srikanth Gottipati, Timothy C. Rodwell, Toby Bloom, Yuching Lai, Vahan Simonyan, Raja Mazumder

Publications and Research

A personalized approach based on a patient's or pathogen’s unique genomic sequence is the foundation of precision medicine. Genomic findings must be robust and reproducible, and experimental data capture should adhere to findable, accessible, interoperable, and reusable (FAIR) guiding principles. Moreover, effective precision medicine requires standardized reporting that extends beyond wet-lab procedures to computational methods. The BioCompute framework (https://w3id.org/biocompute/1.3.0) enables standardized reporting of genomic sequence data provenance, including provenance domain, usability domain, execution domain, verification kit, and error domain. This framework facilitates communication and promotes interoperability. Bioinformatics computation instances that employ the BioCompute framework are easily relayed, repeated …

A New Insight Into Underlying Disease Mechanism Through Semi-Parametric Latent Differential Network Model, Yong He, Jiadong Ji, Lei Xie, Xinsheng Zhang, Fuzhong Xue

Publications and Research

Background

In genomic studies, to investigate how the structure of a genetic network differs between two experiment conditions is a very interesting but challenging problem, especially in high-dimensional setting. Existing literatures mostly focus on differential network modelling for continuous data. However, in real application, we may encounter discrete data or mixed data, which urges us to propose a unified differential network modelling for various data types.

Results

We propose a unified latent Gaussian copula differential network model which provides deeper understanding of the unknown mechanism than that among the observed variables. Adaptive rank-based estimation approaches are proposed with the assumption …

The International Conference On Intelligent Biology And Medicine (Icibm) 2018: Bioinformatics Towards Translational Applications, Xiaoming Liu, Lei Xie, Zhijin Wu, Kai Wang, Zhongming Zhao, Jianhuan Ruan, Degui Zhi

Publications and Research

The 2018 International Conference on Intelligent Biology and Medicine (ICIBM 2018) was held on June 10–12, 2018, in Los Angeles, California, USA. The conference consisted of a total of eleven scientific sessions, four tutorials, one poster session, four keynote talks and four eminent scholar talks, which covered a wild range of aspects of bioinformatics, medical informatics, systems biology and intelligent computing. Here, we summarize nine research articles selected for publishing in BMC Bioinformatics.

Using Physical Contact Heterogeneity And Frequency To Characterize Dynamics Of Human Exposure To Nonhuman Primate Bodily Fluids In Central Africa, Victor Narat, Mamdou Kampo, Thibut Heyer, Stephanie Rupp, Philippe Ambata, Richard Njouom, Tamara Giles-Vernick

Publications and Research

Emerging infectious diseases of zoonotic origin constitute a recurrent threat to global health. Nonhuman primates (NHPs) occupy an important place in zoonotic spillovers (pathogenic transmissions from animals to humans), serving as reservoirs or amplifiers of multiple neglected tropical diseases, including viral hemorrhagic fevers and arboviruses, parasites and bacteria, as well as retroviruses (simian foamy virus, PTLV) that are pathogenic in human beings. Hunting and butchering studies in Africa characterize at-risk human social groups, but overlook critical factors of contact heterogeneity and frequency, NHP species differences, and meat processing practices. In southeastern Cameroon, a region with a history of zoonotic emergence …

Understanding Urbanization: A Study Of Census And Satellite-Derived Urban Classes In The United States, 1990-2010, Deborah Balk, Stefan Leyk, Bryan Jones, Mark R. Montgomery, Anastasia Clark

Publications and Research

Most of future population growth will take place in the world’s cities and towns. Yet, there is no well-established, consistent way to measure either urban land or people. Even censusbased urban concepts and measures undergo frequent revision, impeding rigorous comparisons over time and place. This study presents a new spatial approach to derive consistent urban proxies for the US. It compares census-designated urban blocks with proxies for landbased classifications of built-up areas derived from time-series of the Global Human Settlement Layer (GHSL) for 1990–2010. This comparison provides a new way to understand urban structure and its changes: Most land that …

Non-Pharmacological Solutions To Sleep And Circadian Rhythm Disruption: Voiced Bedside Experiences Of Hospice And End-Oflife Staff Caregivers, Rana Sagha Zadeh, Elizabeth Capezuti, Paul Eshelman, Nicole Woody, Jennifer Tiffany, Ana C. Krieger

Publications and Research

Background: Sleep disturbance is a significant issue, particularly for patients with advanced terminal illness. Currently, there are no practice-based recommended approaches for managing sleep and circadian disruptions in this population. To address this gap, a cross-sectional focus group study was performed engaging 32 staff members at four hospices/end-of-life programs in three demographically diverse counties in New York State.

Methods: Participants responded to structured open-ended questions. Responses were transcribed and subjected to qualitative content analysis. The themes and recommendations for improved practice that emerged were tabulated using Atlas TI qualitative software.

Results: This report details the experiences of hospice and end-of-life …

Nano-Based Systems And Biomacromolecules As Carriers For Metallodrugs In Anticancer Therapy, Mina Poursharifi, Marek T. Wlodarczyk, Aneta J. Mieszawska

Publications and Research

Since the discovery of cisplatin and its potency in anticancer therapy, the development of metallodrugs has been an active area of research. The large choice of transition metals, oxidation states, coordinating ligands, and different geometries, allows for the design of metal-based agents with unique mechanisms of action. Many metallodrugs, such as titanium, ruthenium, gallium, tin, gold, and copper-based complexes have been found to have anticancer activities. However, biological application of these agents necessitates aqueous solubility and low systemic toxicity. This minireview highlights the emerging strategies to facilitate the in vivo application of metallodrugs, aimed at enhancing their solubility and bioavailability, …

But Are They Actually Healthier? Challenging The Health/Wellness Divide Through The Ethnography Of Embodied Ecological Heritage, Kristina Baines

Publications and Research

A holistic definition of ‘health’ remains difficult to operationalize, despite decades of attempts by medical anthropologists and the World Health Organization to do so. Anthropologists routinely reject dichotomous notions – belief vs. knowledge, wellness vs. health, mental vs. physical, environment vs. self – yet demands for physiological evidence of ‘health’ persist. In this article, I ask what evidence would sufficiently demonstrate health, and explore the possibility of measures that move beyond the physiological. Using ethnographic data collected in indigenous Maya communities in Belize and in immigrant communities in New York City, I argue that ecological heritage practices can provide a …

Interference And Control Of The Nosocomial Transmission Of Methicillin-Resistant Staphylococcus Aureus, Sen Pei, Flaviano Morone, Fredrik Liljeros, Hernan Makse, Jeffrey L. Shaman

Publications and Research

Methicillin-resistant Staphylococcus aureus (MRSA) is a continued threat to human health in both community and healthcare settings. In hospitals, control efforts would benefit from accurate estimation of asymptomatic colonization and infection importation rates from the community. However, developing such estimates remains challenging due to limited observation of colonization and complicated transmission dynamics within hospitals and the community. Here, we develop an inference framework that can estimate these key quantities by combining statistical filtering techniques, an agent-based model, and real-world patient-to-patient contact networks, and use this framework to infer nosocomial transmission and infection importation over an outbreak spanning 6 years in …

Effects Of Urbanization On The Foraging Ecology And Microbiota Of The Generalist Seabird Larus Argentatus, Matthew Fuirst, Richard R. Veit, Megan Hahn, Nolwenn Dheilly, Lesley H. Thorne

Publications and Research

Larus gull species have proven adaptable to urbanization and due to their generalist feeding behaviors, they provide useful opportunities to study how urban environments impact foraging behavior and host-associated microbiota. We evaluated how urbanization influenced the foraging behavior and microbiome characteristics of breeding herring gulls (Larus argentatus) at three different colonies on the east coast of the United States. Study colonies represented high, medium and low degrees of urbanization, respectively. At all colonies, gulls frequently foraged at landfills and in other urban environments, but both the use of urban environments and gull foraging metrics differed with the degree of urbanization. …

Nurse Practitioner Knowledge, Attitudes, And Beliefs When Caring For Transgender People, Catherine Paradiso, Robin M. Lally

Publications and Research

Purpose: The aim of this study was to explore Nurse Practitioner (NP) knowledge, attitudes, and beliefs when working with transgender people and to inform about Practitioner education needs.

Methods: A qualitative descriptive design was used to explore (NP) experiences. Focused semistructured interviews were conducted in 2016 with 11 (N = 11) NPs in the northeastern United States who represent various years of experience and encounters with transgender patients. The interviews explored NP knowledge attitudes and beliefs when caring for transgender patients and described their overall experiences in rendering care in the clinical setting. The interviews were professionally transcribed and analyzed …

A Classroom Activity For Teaching Kohlberg’S Theory Of Moral Development, Cheryl L. Carmichael, Anna M. Schwartz, Maureen Coyle, Matthew H. Goldberg

Publications and Research

In two studies, we demonstrate an engaging classroom activity that facilitates student learning about Kohlberg’s theory of moral development by using digital resources to foster active, experiential learning. In addition to hearing a standard lecture about moral development, students watched a video of a morally provocative incident, then worked in small groups to classify user comments posted in response to the video according to Kohlberg’s six stages. Students in both studies found the activity enjoyable and useful. Moreover, students’ scores on a moral development quiz improved after completing the activity (Study 1), and students who completed the activity in addition …

Prefronto-Cerebellar Neuromodulation Affects Appetite In Obesity, Elena M. Marron, Raquel Viejo-Sobera, Guillem Cuatrecasas, Diego Redolar-Ripoll, Pilar García Lorda, Abhishek Datta, Marom Bikson, Greta Magerowksi, Miguel Alonso-Alonso

Publications and Research

Human neuroimaging studies have consistently reported changes in cerebellar function and integrity in association with obesity. To date, however, the nature of this link has not been studied directly. Emerging evidence suggests a role for the cerebellum in higher cognitive functions through reciprocal connections with the prefrontal cortex. The purpose of this exploratory study was to examine appetite changes associated with noninvasive prefronto-cerebellar neuromodulation in obesity. 12 subjects with class I obesity (mean BMI 32.9 kg/m2) underwent a randomized, single-blinded, sham-controlled, crossover study, during which they received transcranial direct current stimulation (tDCS; active/sham) aimed at simultaneously enhancing the activity of …

Gofish: A Versatile Nested Pcr Strategy For Environmental Dna Assays For Marine Vertebrates, Mark Y. Stoeckle, Mithun Das Mishu, Zachary Charlop-Powers

Publications and Research

Here we describe GoFish, a strategy for single-species environmental DNA (eDNA) presence/absence assays using nested PCR. The assays amplify a mitochondrial 12S rDNA segment with vertebrate metabarcoding primers, followed by nested PCR with M13-tailed, species-specific primers. Sanger sequencing confirms positives detected by gel electrophoresis. We first obtained 12S sequences from 77 fish specimens for 36 northwestern Atlantic taxa not well documented in GenBank. Using these and existing 12S records, we designed GoFish assays for 11 bony fish species common in the lower Hudson River estuary and tested seasonal abundance and habitat preference at two sites. Additional assays detected nine cartilaginous …

Forever? Or Ursula K. Le Guin Makes America Great Again By Repositioning Trump As The Dispossessed, Marleen S. Barr

Publications and Research

This is a poem about Ursula K. Le Guin and Trump.

Open Source Foundations For Spatial Decision Support Systems, Jochen Albrecht

Publications and Research

Spatial Decision Support Systems (SDSS) were a hot topic in the 1990s, when researchers tried to imbue GIS with additional decision support features. Successful practical developments such as HAZUS or CommunityViz have since been built, based on commercial desktop software and without much heed for theory other than what underlies their process models. Others, like UrbanSim, have been completely overhauled twice but without much external scrutiny. Both the practical and the theoretical foundations of decision support systems have developed considerably over the past 20 years. This article presents an overview of these developments and then looks at what corresponding tools …