Digital Commons Network^™

Proteasome Mapping Reveals Sexual Dimorphism In Tissue-Specific Sensitivity To Protein Aggregations, Edmund Charles Jenkins, Nagma Shah, Maria Gomez, Gabriella Casalena, Dazhi Zhao, Timothy C. Kenny, Sara Rose Guariglia, Giovanni Manfredi, Doris Germain

Publications and Research

Defects in the proteasome can result in pathological proteinopathies. However, the pathogenic role of sex- and tissue-specific sensitivity to proteotoxic stress remains elusive. Here, we map the proteasome activity across nine tissues, in male and female mice, and demonstrate strong sexual dimorphism in proteasome activity, where females have significantly higher activity in several tissues. Further, we report drastic differences in proteasome activity among tissues, independently of proteasome concentration, which are exacerbated under stress conditions. Sexual dimorphism in proteasome activity is confirmed in a SOD1ALS mouse model, in which the spinal cord, a tissue with comparatively low proteasome activity, is severely …

Transposon Mutagenesis In Mycobacterium Kansasii Links A Small Rna Gene To Colony Morphology And Biofilm Formation And Identifies 9,885 Intragenic Insertions That Do Not Compromise Colony Outgrowth, William C. Budell, Gabrielle A. Germain, Niklas Janisch, Zaid Mckie-Krisberg, Anitha D. Jayaprakash, Andrew E. Resnick, Luis E. N. Quadri

Publications and Research

Mycobacterium kansasii (Mk) is a resilient opportunistic human pathogen that causes tuberculosis-like chronic pulmonary disease and mortality stemming from comorbidities and treatment failure. The standard treatment of Mk infections requires costly, long-term, multidrug courses with adverse side effects. The emergence of drug-resistant isolates further complicates the already challenging drug therapy regimens and threatens to compromise the future control of Mk infections. Despite the increasingly recognized global burden of Mk infections, the biology of this opportunistic pathogen remains essentially unexplored. In particular, studies reporting gene function or generation of defined mutants are scarce. Moreover, no transposon (Tn) mutagenesis tool has been …

Effects Of Speech Cues In French-Speaking Children With Dysarthria, Erika S. Levy, Gemma Moya-Galé, Younghwa Michelle Chang, Luca Campanelli, Andrea A. N. Macleod, Sergio Escorial, Christelle Maillart

Publications and Research

Background: Articulatory excursion and vocal intensity are reduced in many children with dysarthria due to cerebral palsy (CP), contributing to the children’s intelligibility deficits and negatively affecting their social participation. However, the effects of speech-treatment strategies for improving intelligibility in this population are understudied, especially for children who speak languages other than English. In a cueing study on English-speaking children with dysarthria, acoustic variables and intelligibility improved when the children were provided with cues aimed to increase articulatory excursion and vocal intensity. While French is among the top 20 most spoken languages in the world, dysarthria and its management in …

African Naked Mole-Rat Colony Behavior Based On Whole Colony Radio Frequency Identification (Colony Tt-2, April 2015), Dan Mccloskey, Michael E. Kress

Publications and Research

This file contains Radio Frequency Identification (RFID) data for routine activity of members of the TT-2 colony during a 26 day period in April 2015. The data are organized into a state matrix where the last known location for each of the 49 animals in the colony is listed in each row. A new row means that the raw data file updated the location of one animal. The leftmost column gives the date and time of the event, the headers for the other 49 columns give the RFID code for each of the animals in the colony. Animals demonstrated to …

Carbon Dioxide Attracts Nesting Behavior In Captive African Naked Mole-Rats, Dan Mccloskey

Publications and Research

This dataset contains raw Radio Frequency Identification data for a 185 hour gas infusion study conducted in the TT-2 colony at the College of Staten Island in May-June 2019. The purpose of this experiment was to determine whether colony members would be attracted to a chamber with elevated carbon dioxide levels matching the highest values recorded in the typical colony nest. The results show a significant attraction to the CO2-infused chamber during and after the period of CO2 in=fusion, with the relocation of the colony nest to this site for the first time in the history of this colony. These …

The Crime Control Effects Of A Police Sub-Station Within A Business-Improvement District: A Quasi-Experimental Synthetic Control Evaluation, Eric L. Piza, Andrew P. Wheeler, Nathan T. Connealy, Shun Q. Feng

Publications and Research

Research Summary:

The current study analyzes the crime reduction effect of a police sub-station operating within a business improvement district in Newark, NJ. Synthetic control methods were used to create a control group that was statistically equivalent to the cumulative street units in the target area. Significant reductions of burglary and motor vehicle theft were observed in the target area as compared to a synthetic control area over the post-intervention period. Robbery and theft from auto, conversely, suffered from spatial displacement. Of the six police actions included in the process evaluation, quality-of-life summonses and directed patrols increased in the post-intervention …

Proceedings Of The Cuny Games Conference 6.0, Robert O. Duncan, Joseph Bisz, Christina Boyle, Kathleen Offenholley, Maura A. Smale, Carolyn Stallard, Deborah Sturm

Publications and Research

The CUNY Games Network is an organization dedicated to encouraging research, scholarship and teaching in the developing field of games-based learning. We connect educators from every campus and discipline at CUNY and beyond who are interested in digital and non-digital games, simulations, and other forms of interactive teaching and inquiry-based learning. These proceedings summarize the CUNY Games Conference 6.0, where scholars shared research findings at a three-day event to promote and discuss game-based pedagogy in higher education. Presenters could share findings in oral presentations, posters, demos, or play testing sessions. The conference also included workshops on how to modify existing …

Casualization: A Primer, Aaron Barlow

Publications and Research

The problem of casualization (the increasing reliance on adjunct and contingent faculty) grows in American higher education each year. Yet, for all of the attention now being paid to the plight of the adjuncts, few understand exactly what is happening and why, or what the impact is on colleges and univerrsitties.

Exploring Sexual Dimorphism Of The Modern Human Talus Through Geometric Morphometric Methods, Rita Sorrentino, Maria Giovanna Belcastro, Carla Figus, Nicholas B. Stephens, Kevin Turley, William Harcourt-Smith, Timothy M. Ryan, Stefano Benazzi

Publications and Research

Sex determination is a pivotal step in forensic and bioarchaeological fields.Generally,scholars focus on metric or qualitative morphological features,but in the last few years several contributions have applied geometric-morphometric (GM) techniques to overcome limitations of traditional approaches. In this study,we explore sexual dimorphism in modern human tali from three early 20th century populations (Sassari and Bologna, Italy; NewYork, USA) at intra- and interspecific population levels using geometric morphometric (GM) methods.Statistical analyses were performed using shape,form,and size variables.Our results do not show significant differences in shape between males and females, either considering the pooled sample or the individual populations. Differences in talar …

Eye-Movement Benchmarks In Heritage Language Reading, Olga Parshina, Anna K. Laurinavivhyute, Irina A. Sekerina

Publications and Research

This eye-tracking study establishes basic benchmarks of eye movements during reading in heritage language (HL) by Russian-speaking adults and adolescents of high (n = 21) and low proficiency (n = 27). Heritage speakers (HSs) read sentences in Cyrillic, and their eye movements were compared to those of Russian monolingual skilled adult readers, 8-yearold children and L2 learners. Reading patterns of HSs revealed longer mean fixation durations, lower skipping probabilities, and higher regressive saccade rates than in monolingual adults. High-proficient HSs were more similar to monolingual children, while low-proficient HSs performed on par with L2 learners. Low-proficient HSs differed from high-proficient …

Daerim Dong As A Chinatown: Setbacks And Challenges, Wendy W. Tan

Publications and Research

While there is not a single Chinese paifang, or any establishment targeted for tourist attractions, Daerim Dong in Seoul, due to its high concentration of Chinese population and business activities, has been considered as an unofficial 2nd Korean Chinatown. However, at the same time, many indicators are also pointing to the discouraging fact that the path toward making this plan a reality is full of bumps. Why is this conflicting situation happening? To satisfy her own curiosity, the author did intensive literature research and also made a field trip to this district. This essay states some of her findings.

The Effects Of Caffeine Ingestion On Measures Of Rowing Performance: A Systematic Review And Meta-Analysis, Jozo Grgic, Francisco Javier Diaz-Lara, Juan Del Coso, Michael J. Duncan, Jason Tallis, Craig Pickering, Brad J. Schoenfeld, Pavle Mikulic

Publications and Research

The purpose of this paper was to conduct a systematic review and a meta-analysis of studies examining the acute effects of caffeine ingestion on measures of rowing performance. Crossover and placebo-controlled experiments that investigated the effects of caffeine ingestion on measures of rowing performance were included. The PEDro checklist was used to assess the methodological quality of the included studies. Seven studies of good and excellent methodological quality were included. None of the included studies examined on-water rowing. The majority of studies that were included in the meta-analysis used a 2000m rowing distance with only one using 1000m distance. Results …

Placental Histopathology In Late Preterm Infants: Clinical Implications, Kristina Ericksen, Joshua Fogel, Rita P. Verma

Publications and Research

Background: The etiopathogenesis of late preterm (LPT) birth is undetermined. Placental histopathology, which reflects an adverse intrauterine environment and is reportedly associated with preterm labor and neonatal morbidities, has not been studied in LPT infants.

Purpose: We investigated placental pathological lesion as markers of an adverse intrauterine environment during LPT labor.

Methods: This retrospective case-control study compared placental histopathological and clinical variables between LPT and term neonates. Placental variables included chorioamnionitis, funisitis, hemorrhage, abruption, infarction, calcification, and syncytial knots. Maternal variables included age, substance abuse, pregnancyassociated diabetes mellitus and hypertension, duration of rupture of membrane, antibiotic use, and magnesium sulfate, …

Raw Veganism: The Human Diet, Carlo Alvaro

Publications and Research

In this chapter, I present some compelling evidence that points to the conclusion that the human species has a specific diet, which is a raw vegan diet of fresh fruit, tender leafy greens, and a moderate amount of nuts and seeds. Out of the hundreds of thousands of species in the world, the only one—ours—cooks food. Not surprisingly, our species is the only one that suffers from numerous maladies. In other words, the argument is that the consumption of cooked food (especially animal-based) is unhealthful and undermines our nature. I present undeniable evidence, from evolutionary science to nutrition science, showing …

A Real-World Analysis Of Patient Characteristics And Predictors Of Hospitalization Among Us Medicare Beneficiaries With Respiratory Syncytial Virus Infection, Veronique Wyffels, Furaha Kariburyo, Sandra Gavart, Roman Fleischhackl, Huseyin Yuce

Publications and Research

Introduction: Little has been published on respiratory syncytial virus (RSV) among Medicare patients at high risk (HR) of RSV complications due to age or comorbidity. Methods: Adult patients (at least 18 years of age) with at least 1 diagnostic code for RSV were identified using the 5% US Medicare database from 2011 through 2015. Patients were required to have continuous health plan enrollment for 180 days pre- and 180 days post-RSV diagnosis (baseline and follow-up periods, respectively). HR was defined as diagnosis of chronic lung disease, congestive heart failure, or weakened immune system for 180 days during the base-line period. …

Polymers For Extrusion‐Based 3d Printing Of Pharmaceuticals: A Holistic Materials–Process Perspective, Mohammad A. Azad, Deborah Olawuni, Georgia Kimbell, Abu Zayed Badruddoza, Md. Shahadat Hossain, Tasnim Sultana

Publications and Research

Three dimensional (3D) printing as an advanced manufacturing technology is progressing to be established in the pharmaceutical industry to overcome the traditional manufacturing regime of ʹone size fits for allʹ. Using 3D printing, it is possible to design and develop complex dosage forms that can be suitable for tuning drug release. Polymers are the key materials that are necessary for 3D printing. Among all 3D printing processes, extrusion‐based (both fused deposition modeling (FDM) and pressure‐assisted microsyringe (PAM)) 3D printing is well researched for pharmaceutical manufacturing. It is important to understand which polymers are suitable for extrusion‐based 3D printing of pharmaceuticals …

Evaluation Of Health Literacy And Depression Literacy Among Korean Americans, Kunsook Bernstein, Shinhi Han, Young-Me Lee, Oisaeng Hong

Publications and Research

Low health literacy is closely related to a higher rate of hospitalization and of emergency services usage, leading to billions of dollars in avoidable health care costs and contributing to individuals’ poor physical and mental health. While Korean Americans (KAs) have a high prevalence of general health and mental health problems, relatively little is known about their health and mental health literacy, specifically their depression literacy. This study aims to evaluate KAs’ health literacy and depression literacy, as related to sociodemographic characteristics. An exploratory study was conducted with 681 community-residing adult KAs using the Center for Epidemiologic Studies Depression (CES-D) …

Open To What? A Critical Evaluation Of Oer Efficacy Studies, Ian Mcdermott

Publications and Research

This selective literature review evaluates open educational resources (OER) efficacy studies through the lens of critical pedagogy. OER have radical potential as transformative tools for critical pedagogy or they can serve as a cost-free version of the status quo, inclined toward propagating austerity. This review analyzes studies published since 2008 with regard to cost, access, pedagogy, commercialization, and labor. These criteria are used to make explicit subjects indirectly addressed, if not ignored completely, in the existing literature. Typically, ample attention is paid to a study’s design and methodology but the underlying institutional infrastructure and decision-making process is unexamined. What emerges …

Recording Studios Since 1970, Eliot Bates

Publications and Research

Like many other specialty, purpose-built spaces, we tend to think of recording studios in instrumental terms, meaning that the space is defined in relation to the nominal type of work that the space is instrumental towards. While audio recordings have been made in spaces since 1877, not all of these spaces tend to be regarded as recording studios, partly since so many recordings were made in environments designed for other types of work; indeed, much of the first seventy years of US and UK recorded music history transpired at radio stations, concert halls and lightly treated mixed-use commercial spaces (e.g. …

Google-Truthing To Assess Hot Spots Of Food Retail Change: A Repeat Cross-Sectional Street View Of Food Environments In The Bronx, New York, Nevin Cohen, Michael Chrobok, Olivia Caruso

Publications and Research

Google Street View (GSV) images can be used to “ground-truth” current and historical food retail data from approximately 2007 - when GSV was launched in a few US cities - to the present, facilitating analyses of food environments over time. A review of GSV images of all food retailers listed in a government database of licensed establishments in the Bronx, New York enabled records to be verified, businesses classified, and retail change quantified. The data revealed several trends likely to affect food access and health: increasing overall numbers of food retailers; the growth of dollar stores; and numerous openings, closings, …

The Research 101 Certificate Program At A Community College: Giving All Students The Chance To Learn Basic Information Literacy Skills, Neera Mohess

Publications and Research

Many community college students are ill prepared to do scholarly research. In order to mitigate this, librarians at our campus created the Research 101 Certificate Program in 2016. These workshops provide an access point for any student who wishes to strengthen their information literacy skill set. This essay describes the inception of the program, its pedagogical rationale, administration and participation outcomes. Suggestions for implementation at local institutions are also provided.

Exploring The Evolution Of Drought Characteristics In Balochistan, Pakistan, Shoaib Jamro, Falak Naz Channa, Ghulam Hussain Dars, Kamran Ansari, Nir Krakauer

Publications and Research

In the wake of a rapidly changing climate, droughts have intensified, in both duration and severity, across the globe. The Germanwatch long-term Climate Risk Index ranks Pakistan among the top 10 countries most affected by the adverse effects of climate change. Within Pakistan, the province of Balochistan is among the most vulnerable regions due to recurring prolonged droughts, erratic precipitation patterns, and dependence on agriculture and livestock for survival. This study aims to explore how the characteristics of droughts have evolved in the region from 1902–2015 using 3-month and 12-month timescales of a popular drought index, the Standardized Precipitation Evapotranspiration …

If It Looks Like Scholarship..., Aaron Barlow

Publications and Research

No abstract provided.

Tests Of Revisions To The Norbeck Social Support Questionnaire, Eileen Gigliotti, William Ellery Samuels

Publications and Research

Objectives:To compare the accuracy of averaged scores from the original Norbeck Social Support Questionnaire (NSSQ)and averaged scores from each of three new NSSQ versions (NSSQ-R.aid, NSSQ-R.n/a, and NSSQ-R.format). These three new versions of the widely used NSSQ were developed to address three previously identified concerns regarding score accuracy: the Aid subscale’s examples of aid, lack of an n/a response option, and the network nomination/rating procedure.Missing data rates were also assessed.Methods:A convenience sample (N=223) completed one of the four NSSQ versions. Score accuracy (restriction) was assessed by size of correlation between averaged scores (averaged score/network size) and network size, with low …

Capitalism And The Immigrant Rights Movement In The United States, Marcel Paret, Sofya Aptekar, Shannon Gleeson

Publications and Research

Social movements are full of contradictions, and an inherent tension often emerges between reformist and radical flanks. This becomes especially true as activists attempt to draw connections between varied aims such as opposition to globalization and support for immigrants. During the 1999 Battle of Seattle, the movement focused on opposing neoliberalism (Graeber 2002) and advocating for alternative visions of globalization (Reitan 2012). Some activists also noted the hypocrisy of opening borders to capital while militarizing the borders for migrants. Yet, in the end, immigrant rights movements and their central issues did not feature prominently in Seattle or later anti-globalization efforts. …

The Borders Of Dominicanidad—Interview With Lorgia Garcia Peña, Nelson Santana, Amaury Rodríguez

Publications and Research

Dr. Lorgia García Peña is associate professor of Latinx Studies at Harvard University and the author of The Borders of Dominicanidad: Race, Nations and Archives of Contradictions (Duke, Fall 2016). Lorgia García Peña’s book delves deep into Dominican society and history by dissecting foundational myths and state-sponsored propaganda. Lorgia García Peña also looks at Dominican alternative cultural production and the socio-political resistance found in performance art and Afro-Dominican popular religions. In the most recent roundtable installment from the Ethnic Studies Rise initiative that celebrates the work and legacy of García Peña's scholarship, translator and scholar Kaiama Glover argued that [Lorgia …

Weaving Forms Of Resistance: The Museo De La Solidaridad And The Museo Internacional De La Resistencia Salvador Allende, Carla Macchiavello Cornejo

Publications and Research

From the starting point of a 1975 artwork made by Norwegian artist Kjartan Slettemark in Sweden to stop a tennis match in resistance to the Chilean military dictatorship, this article reframes the linear image of networks of solidarity and resistance through the gaps and connectivity of a mesh. It expands the figure of the mesh taken from critical materialism into the affective realm of art, historiography, and art institutions by exploring the cases of the museums Museo de la Solidaridad (1971–1974) and Museo Internacional de la Resistencia “Salvador Allende” (1975–1990). As this article delves into various knots and lacunas of …

Effects Of Range Of Motion On Muscle Development During Resistance Training Interventions: A Systematic Review, Brad J. Schoenfeld, Jozo Grgic

Publications and Research

The purpose of this study was to systematically review the literature as to the effects of performing exercise with a full versus partial range of motion (ROM) during dynamic, longitudinal resistance training (RT) programs on changes in muscle hypertrophy. Based on the available literature, we aimed to draw evidence-based recommendations for RT prescription. Six studies were identified as meeting inclusion criteria: four of these studies involved RT for the lower limbs while the other two focused on the upper extremities. The total combined sample of the studies was n = 135, which comprised 127 men and 8 women. The methodological …

Supporting Institutional Objectives By Embedding Mission-Critical Competencies In Credit-Bearing Library Instruction: A Review And Case Study, Derek Stadler, Alexandra Rojas

Publications and Research

This article reviews scholarship of incorporating institutional objectives in academic courses and proposes a method to embed mission-critical competencies in a library instruction course. Few academic institutions focus their mission or core competencies on digital communication. LaGuardia Community College delineates three competencies in its mission: inquiry and problem solving, global learning, and integrative learning. Students exhibit command of these competencies in written, oral, or digital communication. The College defines the digital communication ability as successful collaboration and interaction using online tools, such as discussion boards, either to stage written exchange, or to capture video or oral discussions. Through participation in …

I Was Called, Too: The Life And Work Of Coretta Scott King, Kristopher B. Burrell

Publications and Research

I thought it both appropriate—and overdue—to discuss the significance of Coretta Scott King. And not just as the wife, and eventual widow, of Martin Luther King; but as an important activist and shaper of Dr. King’s ideas. Mrs. King was a significant figure in her own right, but as with many female historical figures her historical importance has often been minimized or negated; and that can lead to erasure, even in plain sight. This has largely been the case with Mrs. King and with black women in the civil rights movement more broadly.