Digital Commons Network^™

Host Modulation And The Inflammatory Response, Carleigh Fraley, Jennifer Knox-Rodriguez, Diana V. Macri

Publications and Research

Host modulation therapy may be effective in controlling the immune response responsible for periodontal diseases.

Metabolic Reprogramming By C-Met Inhibition As A Targetable Vulnerability In Glioblastoma, Trang Thi Thu Nguyen, Enyuan Shang, Georg Karpel-Massler, Markus D. Siegelin

Publications and Research

The elucidation of better treatments for solid tumors and especially malignant glial tumors is a priority. Better understanding of the molecular underpinnings of treatment response and resistance are critical determinants in the success for this endeavor. Recently, a battery of novel tools have surfaced that allow to interrogate tumor cell metabolism to more precise extent than this was possible in the earlier days. At the forefront of these developments are the extracellular flux and carbon tracing analyses. Through utilization of these techniques our group made the recent observation that acute and chronic c-MET inhibition drives fatty acid oxidation that in …

Understanding The Dimensions Of Medical Crowdfunding: A Visual Analytics Approach, Jie Ren, Viju Raghupathi, Wullianallur Raghupathi

Publications and Research

Background: Medical crowdfunding has emerged as a growing field for fundraising opportunities. Some environmental trends have driven the emergence of campaigns to raise funds for medical care. These trends include lack of medical insurance, economic backlash following the 2008 financial collapse, and shortcomings of health care regulations.

Objective: Research regarding crowdfunding campaign use, reasons, and effects on the provision of medical care and individual relationships in health systems is limited. This study aimed to explore the nature and dimensions of the phenomenon of medical crowdfunding using a visual analytics approach and data crawled from the GoFundMe crowdfunding platform in 2019. …

From Brooklyn To “Brooklyn” The Cultural Transformations Of Leisure, Pleasure, And Taste, Emily Holloway

Publications and Research

To tell the story of Brooklyn’s complex history in hospitality and cuisine is to tell a story about the tensions of high and low culture, of the mobility of capital and residents, and of the tremendous influence yielded by macroeconomic change. A sleepy bedroom community for the eighteenth and much of the early nineteenth centuries, Brooklyn’s waterfront (both historically and today) is deeply tied to its nineteenth and twentieth-century industrial heritage. The ad hoc economies that supported factory and dock workers, included boardinghouses, saloons, brothels, food carts, and amusement parks and drew a stark contrast to those of factory and …

Transcutaneous Auricular Vagus Nerve Stimulation-Paired Rehabilitation For Oromotor Feeding Problems In Newborns: An Open-Label Pilot Study, Bashar W. Badran, Dorothea D. Jenkins, Daniel Cook, Sean Thompson, Morgan Darcy, William H. Devries, Georgia Mappin, Philipp Summers, Marom Bikson, Mark S. George

Publications and Research

Neonates born premature or who suffer brain injury at birth often have oral feeding dysfunction and do not meet oral intake requirements needed for discharge. Low oral intake volumes result in extended stays in the hospital (>2 months) and can lead to surgical implant and explant of a gastrostomy tube (G-tube). Prior work suggests pairing vagus nerve stimulation (VNS) with motor activity accelerates functional improvements after stroke, and transcutaneous auricular VNS (taVNS) has emerged as promising noninvasive form of VNS. Pairing taVNS with bottle-feeding rehabilitation may improve oromotor coordination and lead to improved oral intake volumes, ultimately avoiding the …

Communication And Meaning-Making Are Central To Understanding Aesthetic Response In Any Context, Melissa J. Dolese, Aaron Kozbelt

Publications and Research

Conceptions of aesthetic experience extend beyond beauty to include any evaluative judgment or emotion experienced in response to an artwork. In this opinion piece, we discuss the nature of artistic communication and how it might be facilitated inside and outside of museum settings.

Collection Development At Two Armenian University Libraries: A Conversation With Librarians And Faculty, John Carey, D. Aram Donabedian, Arshak Balayan

Publications and Research

In the summer of 2016 two Hunter College librarians, working with a colleague in the Republic of Armenia, conducted an IRB-approved focus group at the American University of Armenia in Yerevan, Armenia. This group drew participants from the libraries and other academic departments of the American University of Armenia as well as Yerevan State University, a large public institution. The discussion attempted to ascertain whether these libraries have devised effective strategies to acquire materials and build collections in the face of the challenges they face (budgetary, linguistic, and sometimes political) and whether faculty at these institutions feel their library’s collection …

Lamin Fofana: Blues, Alaina Claire Feldman, Dino Dincer Sirin, Lamin Fofana

Publications and Research

Catalogue for the exhibition "Lamin Fofana: Blues" presented at Baruch College's Mishkin Gallery in 2020.

Adora2a C Allele Carriers Exhibit Ergogenic Responses To Caffeine Supplementation, Jozo Grgic, Craig Pickering, David J. Bishop, Juan Del Coso, Brad J. Schoenfeld, Grant M. Tinsley, Zeljko Pedisic

Publications and Research

Caffeine's ergogenic effects on exercise performance are generally explained by its ability to bind to adenosine receptors. ADORA2A is the gene that encodes A2A subtypes of adenosine receptors. It has been suggested that ADORA2A gene polymorphisms may be responsible for the inter-individual variations in the effects of caffeine on exercise performance. In the only study that explored the influence of variation in ADORA2A—in this case, a common polymorphism (rs5751876)—on the ergogenic effects of caffeine on exercise performance, C allele carriers were identified as “non-responders” to caffeine. To explore if C allele carriers are true “non-responders” to the ergogenic effects of …

Variation In Brown Rat Cranial Shape Shows Directional Selection Over 120 Years In New York City, Emily E. Puckett, Emma Sherratt, Matthew Combs, Elizabeth J. Carlen, William Harcourt-Smith, Jason Munshi-South

Publications and Research

Urbanization exposes species to novel environments and selection pressures that may change morphological traits within a population. We investigated how the shape and size of crania and mandibles changed over time within a population of brown rats (Rattus norvegicus) living in Manhattan, New York, USA, a highly urbanized environment. We measured 3D landmarks on the cranium and mandible of 62 adult individuals sampled in the 1890s and 2010s. Static allometry explained approximately 22% of shape variation in crania and mandible datasets, while time accounted for approximately 14% of variation. We did not observe significant changes in skull size through time …

Preliminary Efficacy Of Motivational Interviewing On Problem Drinkers 55 And Older Compared To Younger Counterparts, Alexis Kuerbis, Sijing Shao, Nehal Vadhan, Jon Morgenstern

Publications and Research

Background: Older adults who drink problematically are the largest group of substance users among those 55 and older. This group often chooses moderation as a goal instead of abstinence, and motivation and self-efficacy are found to have less of an impact on drinking compared to younger adults. No study has examined age effects (specifically 55 and older vs. younger counterparts) on motivational interviewing (MI) compared to brief advice with a sample that includes individuals over 65. Objective: To explore the moderating impact of age on heavy drinkers’ (aged M=50.7 years SD=11.6, range 23-73) response to MI. Methods: Data …

Modulation Of The Pol Ii Ctd Phosphorylation Code By Rac1 And Cdc42 Small Gtpases In Cultured Human Cancer Cells And Its Implication For Developing A Synthetic-Lethal Cancer Therapy, Bo Zhang, Xuelin Zhong, Moira Sauane, Yihong Zhao, Zhi-Liang Zheng

Publications and Research

Rho GTPases, including Rho, Cdc42, Rac and ROP subfamilies, are key signaling molecules in RNA polymerase II (Pol II) transcriptional control. Our prior work has shown that plant ROP and yeast Cdc42 GTPases similarly modulate Ser2 and Ser5 phosphorylation status of the C-terminal domain (CTD) of the Pol II largest subunit by regulating CTD phosphatase degradation. Here, we present genetic and pharmacological evidence showing that Cdc42 and Rac1 GTPase signaling modulates a similar CTD Ser2 and Ser5 phosphorylation code in cultured human cancer cells. While siRNA knockdown of Cdc42 and Rac1, respectively, in HeLa cells increased the level of CTD …

Evolutionary Traits That Enable Scleractinian Corals To Survive Mass Extinction Events, Gal Dishon, Michal Grossowicz, Michael Krom, Gilad Guy, David F. Gruber, Dan Tchernov

Publications and Research

Scleractinian “stony” corals are major habitat engineers, whose skeletons form the framework for the highly diverse, yet increasingly threatened, coral reef ecosystem. Fossil coral skeletons also present a rich record that enables paleontological analysis of coral origins, tracing them back to the Triassic (~241 Myr). While numerous invertebrate lineages were eradicated at the last major mass extinction boundary, the Cretaceous-Tertiary/K-T (66 Myr), a number of Scleractinian corals survived. We review this history and assess traits correlated with K-T mass extinction survival. Disaster-related “survival” traits that emerged from our analysis are: (1) deep water residing (>100 m); (2) cosmopolitan distributions, …

Characterization Of A Sagnac Loop Mirror-Based Hybrid Passive Variable Optical Coupler/Attenuator, Simeon Bikorimana, Muhammad A. Ummy, Abdullah Hossain, Richard Lin, Roger Dorsinville

Publications and Research

The implementation and performance of a unidirectional all-single mode fiber hybrid passive variable optical coupler/attenuator based on a Sagnac loop mirror with a continuous variable coupling ratio using off-the-shelf optical sub-components are discussed. Parameters of two output ports of the unidirectional hybrid passive variable optical coupler/attenuator, such as maximum coupling ratio, insertion loss, excess loss, and wavelength-dependent return loss over the C-band at room temperature are reported. The reflectivity of the Sagnac loop mirror continuously varies from 0.1% to 99.9% by adjusting retarders of a polarization controller. The 3-dB coupling ratio (i.e., 50:50) between the two output ports of the …

Predictor Species: Improving Assessments Of Rare Species Occurrence By Modeling Environmental Co-Responses, Peter R. Thompson, William F. Fagan, Phillip P. A. Staniczenko

Publications and Research

Designing an effective conservation strategy requires understanding where rare species are located. Because rare species can be difficult to find, ecologists often identify other species called conservation surrogates that can help inform the distribution of rare species. Species distribution models typically rely on environmental data when predicting the occurrence of species, neglecting the effect of species' co-occurrences and biotic interactions. Here, we present a new approach that uses Bayesian networks to improve predictions by modeling environmental co-responses among species. For species from a European peat bog community, our approach consistently performs better than single-species models and better than conventional multi-species …

Making Translinguality And Transnationality Visible, Heather M. Robinson, Jonathan Hall, Nela Navarro

Publications and Research

Exploring the roles of pluralistic linguistic and transnational identities at the university level, this book offers a novel approach to translanguaging by highlighting students' perspectives, voices and agency as integral to the subject. Providing an original reconsideration of the impact of translanguaging, this book examines both transnationality and translinguality as ubiquitous phenomena that affect students' lives.

Paleopathological Research In Continental China: Introduction To The Special Section, Elizabeth Berger, Kate Pechenkina

Publications and Research

We set out to assemble this special issue of IJPP with three goals in mind: (1) to familiarize Anglophone readers with research on paleopathology conducted by Chinese scholars; (2) to enhance interest in paleopathological research among Chinese scholars, and to foster the use of differential diagnosis as the key mode of paleopathological analysis; and (3) to initiate integration of pathological analysis of human skeletal collections with historical records documenting early medical practices, epidemics, development and age-related diseases, and demographic records.

The collection of papers that follows present new data, from a range of time periods and geographic and social contexts, …

The Role Of Remediation In Library Reference, William Blick

Publications and Research

While working at a fast paced reference desk at a busy community college, a librarian may encounter many challenging questions and situations. One such problem that may exist on a community college level is that of the very needy student, who not only has issues with information literacy, but with reading competency and computer literacy. The question is: “ on what on level is the librarian responsible for remediating the student in a the brief and confining limitations of the reference interview?” This paper seeks to explore the role of the librarian as he or she relates to remediation and …

Childhood Memories Of Playful Antics And Punishable Acts Risking An Imperfect Future Of Teaching And Learning, Lisa Farley, Debbie Sonu, Julie Garlen, Sandra Chang-Kredl

Publications and Research

This paper takes up the question of risk by examining childhood memories of nuisance-making and punishment shared by 26 participants enrolled in teacher education and/or childhood studies programs. Our analysis surfaces a tension that, on the one hand, idealizes the child as innocent instigator of playful antics and, on the other, produces a child who is guilty of punishable acts. We read these memories as an invitation to theorize a middle ground of the teacher’s role as one of introducing children to a world of limits, while also limiting the force of this very effort.

A Different Set Of Rules? Nlrb Proposed Rule Making And Student Worker Unionization Rights, William A. Herbert, Joseph Van Der Naald

Publications and Research

This article presents data, precedent, and empirical evidence relevant to the National Labor Relations Board (NLRB) proposal to issue a new rule to exclude graduate assistants and other student employees from coverage under the National Labor Relations Act (NLRA). The analysis in three parts. First, the authors show through an analysis of information from other federal agencies that the adoption of the proposed NLRB rule would exclude over 81,000 graduate assistants on private campuses from the right to unionize and engage in collective bargaining. Second, the article presents a legal history from the past half-century about unionization of student employees …

Taking Your Teaching To The Next Level Through The Use Of Oer, Nicole N. Williams

Publications and Research

Faculty creation, adaptation, and adoption of open educational resources (OER) can be used to enrich every aspect of the professor-student teaching relationship. Adding to the body of OER available allows faculty to rethink every aspect of what they teach and refine how they present that information. Having the ability to edit and adapt existing OER provides faculty with the benefits of collaboration, but without the scheduling concerns that often plague collaborative efforts. OER creation can be as simple as licensing handouts and presentation slides for sharing, or as involved as redesigning an entire course. Putting one’s own stamp on OER …

Creating And Using Open Educational Resources (Oer) In Reading And Writing Classes, Christine E. Hutchins

Publications and Research

Creating her own assignments using openly licensed course materials allows this professor and her students to be more creative and to take greater advantage of digital resources.

A Different Set Of Rules? Nlrb Proposed Rule Making And Student Worker Unionization Rights, William A. Herbert, Joseph Van Der Naald

Publications and Research

This article presents data, precedent, and empirical evidence relevant to the National Labor Relations Board (NLRB) proposal to issue a new rule to exclude graduate assistants and other student employees from coverage under the National Labor Relations Act (NLRA). The analysis in three parts. First, the authors show through an analysis of information from other federal agencies that the adoption of the proposed NLRB rule would exclude over 81,000 graduate assistants on private campuses from the right to unionize and engage in collective bargaining. Second, the article presents a legal history from the past half-century about unionization of student employees …

Dissociable Posterior And Anterior Insula Activations In Processing Negative Stimulus Before And After The Application Of Cognitive Reappraisals, Ze Zhang, Tingting Guo, Jin Fan, Xiaofei Wu, Tengteng Tan, Jing Luo

Publications and Research

Although the role of the insular cortex in representing bodily and emotional feelings has been recognized, whether the mid-posterior and anterior parts of the insula act differentially in the encoding and regulation of emotional feelings is still unclear. In this functional magnetic resonance imaging (fMRI) study, we examined the effects of the creative cognitive reappraisals versus the non-creative ordinary reappraisals on the activation pattern of the mid-posterior and anterior insular cortex during the processing of unpleasant pictures by comparing the neural correlates for processing these pictures before and after the application of cognitive reappraisals. We found significant anterior insular activation …

Bella Figura: Understanding Italian Communication In Local And Transatlantic Contexts, Denise Scannell Guida

Publications and Research

Bella figura—beautiful figure—is an idiomatic expression used to reflect every part of Italian life. The phrase appears in travel books and in transnational business guides to describe Italian customs, in sociological research to describe the national characteristics of Italians, and in popular culture to depict thematic constructs and stereotypes, such as the Mafia, romance, and la dolce vita. Scholarly research on bella figura indicates its significance in Italian civilization, yet it remains one of the most elusive concepts to translate. Among the various interpretations and references from foreigners and Italians there is not a single definition that captures the …

Theoretical Analysis Of The Leakage Through The Cement Line Of A Single Osteon, Gaffar Gailani, Stephen Cowin

Publications and Research

This work focuses on the Lacunar–Canalicular Porosity (PLC) of cortical bone which includes the osteons. Osteons are semicylindrical porous structures saturated with fluid within the bone and are approximately 250" role="presentation">μ" role="presentation">μm in diameter. The outer boundary of the osteon is called the cement line. Some studies suggested that the cement line is less highly mineralized and produced evidence that it has less calcium and phosphorus and more sulfur than the neighboring bone lamellae. Most authors assume that the cement line is impermeable, while others assume that some canaliculi are crossing the cement line which will make it …

Community College Incoming Freshman Mathematics Course-Taking, Anders J. Stachelek, Alexandra Logue

Publications and Research

This data set accompanies an article discussing the mathematics course-taking patterns of incoming freshmen students at community colleges.

Artificial Intelligence: A New Paradigm In Obstetrics And Gynecology Research And Clinical Practice, Pulwasha Iftikhar, Marcela V. Kuijpers, Azadeh Khayyat, Aqsa Iftikhar, Maribel Degouvia De Sa

Publications and Research

Artificial intelligence (AI) is growing exponentially in various fields, including medicine. This paper reviews the pertinent aspects of AI in obstetrics and gynecology (OB/GYN) and how these can be applied to improve patient outcomes and reduce the healthcare costs and workload for clinicians.

Herein, we will address current AI uses in OB/GYN, and the use of AI as a tool to interpret fetal heart rate (FHR) and cardiotocography (CTG) to aid in the detection of preterm labor, pregnancy complications, and review discrepancies in its interpretation between clinicians to reduce maternal and infant morbidity and mortality. AI systems can be used …

Work Alienation And Its Gravediggers: Social Class, Class Consciousness, And Activism, Jeremy Sawyer, Anup Gampa

Publications and Research

Work activity is central to human psychology. However, working conditions under capitalist socioeconomic relations have been posited as psychologically alienating. Given the negative impact of work alienation on well-being and mental health, we conducted two studies of the relations between social class, work conditions, and alienation. We also examined factors that might counteract alienation – class consciousness and activism. The utility of a Marxist measure of social class – based on objective work relations – was compared with that of SES and subjective class measures. Study 1 surveyed 240 U.S. adults from diverse socioeconomic backgrounds using Amazon’s Mechanical Turk; Study …

The Public Reckoning: Anti-Debt Futures After #Rickyrenuncia, Sarah Molinari

Publications and Research

This essay argues that the summer 2019 mobilizations in Puerto Rico and the renewed demand for a debt audit help to imagine anti-debt futures that disrupt the terms and temporalities of public debt and indebted lives. The essay discusses one form of debt resistance-a comprehensive citizen debt audit-as central to deepen the process of public reckoning marked by #RickyRenuncia and to build upon the landscapes of protest and solidarity emerging in its wake.