Digital Commons Network^™

Measuring The Evolutionary Rate Of Cooling Of Zz Ceti, Anjum S. Mukadam, Ted Von Hippel, Et Al.

Publications

We have finally measured the evolutionary rate of cooling of the pulsating hydrogen atmosphere (DA) white dwarf ZZ Ceti (Ross 548), as reflected by the drift rate of the 213.13260694 s period. Using 41 yr of time-series photometry from 1970 November to 2012 January, we determine the rate of change of this period with time to be dP/dt = (5.2 ± 1.4) × 10–15 s s–1 employing the O – C method and (5.45 ± 0.79) × 10–15 s s–1 using a direct nonlinear least squares fit to the entire lightcurve. We adopt the dP/dt obtained …

A Spectroscopic Analysis Of The Eclipsing Short-Period Binary V505 Persei And The Origin Of The Lithium Dip, Patrick Baugh, Jeremy R. King, Constantine P. Deliyannis, Ann Merchant Boesgaard

Publications

As a test of rotationally-induced mixing causing the well-known Li dip in older mid-F dwarfs in the local Galactic disk, we utilize high-resolution and -S/N Keck/HIRES spectroscopy to measure the Li abundance in the components of the ∼1 Gyr, [Fe/H]= −0.15 eclipsing short-period binary V505 Per. We find A(Li) ∼ 2.7 ± 0.1 and 2.4 ± 0.2 in the Teff∼6500 and 6450K primary and sec-ondary components, respectively. Previous Teff determinations and uncertainties suggest that each component is located in the midst of the Li dip. If so, their A(Li) are ≥2–5 times larger than A(Li) detections and upper limits observed …

Continuous Development Of Schemes For Parallel Computing Of The Electrostatics In Biological Systems: Implementation In Delphi, Chuan Li, Marharyta Petukh, Lin Li, Emil Alexov

Publications

Due to the enormous importance of electrostatics in molecular biology, calculating the electrostatic potential and corresponding energies has become a standard computational approach for the study of biomolecules and nano-objects immersed in water and salt phase or other media. However, the electrostatics of large macromolecules and macromolecular complexes, including nano-objects, may not be obtainable via explicit methods and even the standard continuum electrostatics methods may not be applicable due to high computational time and memory requirements. Here, we report further development of the parallelization scheme reported in our previous work (J Comput Chem. 2012 Sep 15; 33(24):1960–6.) to include parallelization …

Cancer Missense Mutations Alter Binding Properties Of Proteins And Their Interaction Networks, Hafumi Nisha, Manoj Tyagi, Shaolei Teng, Benjamin A. Shoemaker, Kosuke Hashimoto, Emil Alexov, Stefan Wuchty, Anna R. Panchenko

Publications

Many studies have shown that missense mutations might play an important role in carcinogenesis. However, the extent to which cancer mutations might affect biomolecular interactions remains unclear. Here, we map glioblastoma missense mutations on the human protein interactome, model the structures of affected protein complexes and decipher the effect of mutations on protein-protein, protein-nucleic acid and protein-ion binding interfaces. Although some missense mutations over-stabilize protein complexes, we found that the overall effect of mutations is destabilizing, mostly affecting the electrostatic component of binding energy. We also showed that mutations on interfaces resulted in more drastic changes of amino acid physico-chemical …

Linear Model Estimation Of Nonlinear Systems Using Least-Squares Algorithm5, Alireza Rahrooh, Walter W. Buchanan, Remzi Seker

Publications

This paper presents utilizes Least-Squares Algorithm to obtain more accurate linear models of nonlinear systems using parameter estimation. This approach generates an optimal linear model which is valid over a wide range of trajectories and converges to the desired steady-state value with no errors unlike the existing techniques. The proposed technique is very efficient and does not require storing the data. Therefore, it can easily be used and implemented with limited resources for undergraduate curriculum especially in underdeveloped countries. Most available techniques for linearization of nonlinear system are only valid about the operating point; furthermore, the knowledge of the operating …

70 Da White Dwarfs Identified In Lamost Pilot Survey, J. K. Zhao, A. L. Luo, Terry D. Oswalt, G. Zhao

Publications

We present a spectroscopically identified catalog of 70 DA white dwarfs (WDs) from the LAMOST pilot survey. Thirty-five are found to be new identifications after cross-correlation with the Eisenstein et al. and Villanova catalogs. The effective temperature and gravity of these WDs are estimated by Balmer lines fitting. Most of them are hot WDs. The cooling times and masses of these WDs are estimated by interpolation in theoretical evolution tracks. The peak of the mass distribution is found to be ∼0.6M, which is consistent with prior work in the literature. The distances of these WDs are estimated using the method …

Dispersive Waves In Microstructured Solids, A. Berezovski, J. Engelbrecht, A. Salupere, K. Tamm, T. Peets, Mihhail Berezovski

Publications

The wave motion in micromorphic microstructured solids is studied. The mathematical model is based on ideas of Mindlin and governing equations are derived by making use of the Euler–Lagrange formalism. The same result is obtained by means of the internal variables approach. Actually such a model describes internal fields in microstructured solids under external loading and the interaction of these fields results in various physical effects. The emphasis of the paper is on dispersion analysis and wave profiles generated by initial or boundary conditions in a one-dimensional case.

Tips From The Board Of Broadcast Meteorology For Gaining The Certified Broadcast Meteorologist (Cbm) Designation, Rob Eicher

Publications

These notes are intended to maximize the likelihood that you will pass the AMS CBM evaluation on your first attempt. Typically half of first-time applicants pass the evaluation.

Inquiry-Guided Learning (Igl) In Graphical Communications Course, Lulu Sun, Christopher Grant

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Inquiry-Guided Learning (IGL) is an active learning technique which promotes students critical thinking through guided independent investigation of complex problems without a single solution, which has been studied and implemented by many researchers in science and engineering fields [1-8]. It is believed that IGL can provide an opportunity to the students to explore their desires and consequently enhance students’ learning experience in the classroom. Graphical Communications, as a common course taught at first-year undergraduate level at Embry-Riddle Aeronautical University is designed to familiarize the student with the basic principles of drafting and engineering drawing, to improve three dimensional visualization skills, …

The Role Of Protonation States In Ligand-Receptor Recognition And Binding, Marharyta Petukh, Shannon Stefl, Emil Alexov

Publications

In this review we discuss the role of protonation states in receptor-ligand interactions, providing experimental evidences and computational predictions that complex formation may involve titratable groups with unusual pKa’s and that protonation states frequently change from unbound to bound states. These protonation changes result in proton uptake/release, which in turn causes the pHdependence of the binding. Indeed, experimental data strongly suggest that almost any binding is pH-dependent and to be correctly modeled, the protonation states must be properly assigned prior to and after the binding. One may accurately predict the protonation states when provided with the structures of the unbound …

A Knowledge-Based Clinical Toxicology Consultant For Diagnosing Multiple Exposures, Joel D. Schipper, Douglas D. Dankel Ii, A. Antonio Arroyo, Jay L. Schauben

Publications

Objective: This paper presents continued research toward the development of a knowledge-based system for the diagnosis of human toxic exposures. In particular, this research focuses on the challenging task of diagnosing exposures to multiple toxins. Although only 10% of toxic exposures in the United States involve multiple toxins, multiple exposures account for more than half of all toxin-related fatalities. Using simple medical mathematics, we seek to produce a practical decision support system capable of supplying useful information to aid in the diagnosis of complex cases involving multiple unknown substances.

Methods: The system is automatically trained using data mining …

Gaise In Discipline-Specific Courses, Beverly Wood

Publications

While acknowledging the diverse setting, audience, and purpose of introductory courses, existing research assumes that courses offered by different disciplines share the same goals and teaching practices. The purpose of this study is to examine the objectives for student outcomes and pedagogical delivery of introductory statistics courses designed for students in a specific major, providing explicit evidence for this assumption.

The American Statistical Association’s Guidelines for Assessment and Instruction in Statistics Education (GAISE) are meant to apply to all introductory courses. The College Report’s Goals for Students and Recommendations for Teaching are used as a framework for a qualitative study …

Influence Of Microstructure On Thermoelastic Wave Propagation, Arkadi Berezovski, Mihhail Berezovski

Publications

Numerical simulations of the thermoelastic response of a microstructured material on a thermal loading are performed in the one-dimensional setting to examine the influence of temperature gradient effects at the microstructure level predicted by the thermoelastic description of microstructured solids (Berezovski et al. in J. Therm. Stress. 34:413–430, 2011). The system of equations consisting of a hyperbolic equation of motion, a parabolic macroscopic heat conduction equation, and a hyperbolic evolution equation for the microtemperature is solved by a finite-volume numerical scheme. Effects of microtemperature gradients exhibit themselves on the macrolevel due to the coupling of equations of the macromotion …

Tracers Of Chromospheric Structure. I. Ca Ii H&K Emission Distribution Of 13,000 F, G, And K Stars In Sdss Dr7 Spectroscopic Sample, J. K. Zhao, T. D. Oswalt, G. Zhao, Q. H. Lu, A. L. Luo, L. Y. Zhang

Publications

We present chromospheric activity index S_HK measurements for over 13,000 F, G, and K disk stars with high signal-to-noise ratio (>60) spectra in the Sloan Digital Sky Survey (SDSS) Data Release 7 (DR7) spectroscopic sample. A parameter δS is defined as the difference between S_HK and a “zero” emission line fitted by several of the most inactive stars. The S_HK indices of subgiant stars tend to be much lower than dwarfs, which provide a way to distinguish dwarfs and giants with relatively low-resolution spectra. Cooler stars are generally more active and display a larger scatter than …

Tracers Of Chromospheric Structure. I. Caii H&K Emission Distribution Of 13000 F, G And K Stars In Sdss Dr7 Spectroscopic Sample, J. K. Zhao, T. D. Oswalt, G. Zhao, Q. H. Lu, L. Y. Zhang

Publications

We present chromospheric activity index SHK measurements for over 13,000 F, G and K disk stars with high signal-to-noise ratio (> 60) spectra in the Sloan Digital Sky Survey (SDSS) Data Release 7 (DR7) spectroscopic sample. A parameter S is defined as the difference between SHK and a ‘zero’ emission line fitted by several of the most inactive stars. The SHK indices of subgiant stars tend to be much lower than dwarfs, which provide a way to distinguish dwarfs and giants with relatively low resolution spectra. Cooler stars are generally more active and display a larger scatter than hotter stars. …

X-Ray Source Variability Study Of The M31 Central Field Using Chandra Hrc-1, F. Hofmann, W. Pietsch, M. Henze, F. Haberl, R. Sturm, M. Della Valle, Dieter H. Hartmann, D. Hatzidimitriou

Publications

Context. The central field of the Andromeda galaxy (M 31) has been monitored, using the Chandra HRC-I detector (about 0.1-10 keV energy range) from 2006 to 2012 with the main aim to detect X-rays from optical novae. We present a systematic analysis of all X-ray sources found in the 41 nova monitoring observations, along with 23 M 31 central field HRC-I observations available from the Chandra data archive starting in December 1999. Aims. Based on these observations, we studied the X-ray long-term variability of the source population and especially of X-ray binaries in M 31. Methods. We created a catalogue …

Kelvin-Helmholtz Instability Of The Cme Reconnection Outflow Layer In The Low Corona, Claire Foullon, Erwin Verwichte, Katariina Nykyri, Markus J. Aschwanden, Iain G. Hannah

Publications

New capabilities for studying the Sun allow us to image for the first time the magnetic Kelvin–Helmholtz (KH) instability developing at the surface of a fast coronal mass ejecta (CME) less than 150 Mm above the solar surface. We conduct a detailed observational investigation of this phenomenon, observed off the east solar limb on 2010 November 3, in the EUV with SDO/AIA. In conjunction with STEREO-B/EUVI, we derive the CME source surface position. We ascertain the timing and early evolution of the CME outflow leading to the instability onset. We perform image and spectral analysis, exploring the CME plasma structuring …

Nanobiotechnology Can Boost Crop Production And Quality: First Evidence From Increased Plant Biomass, Fruit Yield And Phytomedicine Content In Bitter Melon (Momordica Charantia), Chittaranjan Kole, Phullara Kole, K Manoj Randunu, Poonam Choudhary, Ramakrishna Podila, Pu Chen Ke, Apparao M. Rao, Richard K. Marcus

Publications

BACKGROUND:

Recent research on nanoparticles in a number of crops has evidenced for enhanced germination and seedling growth, physiological activities including photosynthetic activity and nitrogen metabolism, mRNA expression and protein level, and also positive changes in gene expression indicating their potential use in crop improvement. We used a medicinally rich vegetable crop, bitter melon, as a model to evaluate the effects of seed treatment with a carbon-based nanoparticle, fullerol [C60(OH)20], on yield of plant biomass and fruit characters, and phytomedicine contents in fruits.

RESULTS:

We confirmed the uptake, translocation and accumulation of fullerol through bright field imaging and Fourier transform …

Nature Of The Gas And Dust Around 51 Oph, W F. Thi, F Menard, G Meeus, A Carmona, P Riviere-Marichalar, J C. Augereau, I Kamp, P Woitke, C Pinte, I Mendigutia, C Eiroa, B Montesinos, Sean D. Brittain, W Dent

Publications

Circumstellar disc evolution is paramount for the understanding of planet formation. The GASPS program aims at determining the circumstellar gas and solid mass around ~250 pre-main-sequence Herbig Ae and TTauri stars. We aim to understand the origin and nature of the circumstellar matter orbiting 51 Oph, a young (Myr) luminous B9.5 star. We obtained continuum and line observations with the PACS instrument on board the Herschel Space Observatory and continuum data at 1.2 mm with the IRAM 30m telescope. The SED and line fluxes were modelled using the physico-chemo radiative transfer code ProDiMo. We detected a strong emission by OI …

Academic Major Choice Of International Student-Athletes Competing In The Ncaa, Robin Hardin, Sylvia Trendafilova, Sarah Stokowski, Gi-Yong Koo

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No abstract provided.

Connecting To Our Community: Utilizing Photovoice As A Pedagogical Tool To Connect College Students To Science, Kristin Cook, Cassie F. Quigley

Publications

In this study, we investigated the ways in which university students connected with science through the use of photovoice (Wang & Burris, 1994) as a pedagogical tool. Results indicated that students came to appreciate their connections to the science that operates in their lives as they reflected on and became empowered with regard to the science content behind environmental issues of interest to them on campus. Photovoice allowed students to authentically inquire about local science, as well as the potential to generate change in their own community. This understanding is significant to science educators because first, it empowers learners to …

Precipitation Modulation By The Saint Lawrence River Valley In Association With Transitioning Tropical Cyclones, Shawn M. Milrad, Eyad H. Atallah, John R. Gyakum

Publications

The St. Lawrence River valley (SLRV) is an important orographic feature in eastern Canada that can affect surface wind patterns and contribute to locally higher amounts of precipitation. The impact of the SLRV on precipitation distributions associated with transitioning, or transitioned, tropical cyclones that approached the region is assessed. Such cases can result in heavy precipitation during the warm season, as during the transition of Hurricane Ike (2008). Thirty-eight tropical cyclones tracked within 500 km of the SLRV from 1979 to 2011. Utilizing the National Centers for Environmental Prediction (NCEP) North American Regional Reanalysis (NARR), 19 of the 38 cases …

Asymmetry Of Magnetosheath Flows And Magnetopause Shape During Low Alfvén Mach Number Solar Wind, B. Lavraud, E. Larroque, E. Budnik, V. Génot, J. E. Borovsky, M. W. Dunlop, K. Nykyri, Et Al.

Publications

Previous works have emphasized the significant influence of the solar wind Alfvén Mach number (MA) on magnetospheric dynamics. Here we report statistical, observational results that pertain to changes in the magnetosheath flow distribution and magnetopause shape as a function of solar wind MA and interplanetary magnetic field (IMF) clock angle orientation. We use all Cluster 1 data in the magnetosheath during the period 2001–2010, using an appropriate spatial superposition procedure, to produce magnetosheath flow distributions as a function of location in themagnetosheath relative to the IMF and other parameters. The results demonstrate that enhanced flows in the magnetosheath are expected …

Progress In Developing Poisson-Boltzmann Equation Solvers, Chuan Li, Marharyta Petukh, Emil Alexov

Publications

This review outlines the recent progress made in developing more accurate and efficient solutions to model electrostatics in systems comprised of bio-macromolecules and nano-objects, the last one referring to objects that do not have biological function themselves but nowadays are frequently used in biophysical and medical approaches in conjunction with bio-macromolecules. The problem of modeling macromolecular electrostatics is reviewed from two different angles: as a mathematical task provided the specific definition of the system to be modeled and as a physical problem aiming to better capture the phenomena occurring in the real experiments. In addition, specific attention is paid to …

Modelling And Hazard Analysis For Contaminated Sediments Using Stamp Model And Stpa Tool, Karim Hardy, Franck Guarnieri

Publications

The goal of this article is dual: first, introducing a new model of accident named STAMP (systems-theoretic accident modeling and processes); then applying the model to an innovative process for the treatment of contaminated substances and the re-use of treated substances. This article is a demonstration for a need of a new tool to take into account hazards and safety within socio-technical systems.

A Rational Free Energy-Based Approach To Understanding And Targeting Disease-Causing Missense Mutations., Zhe Zhang, Shawn Witham, Marharita Petukh, Gautier Moroy, Maria Miteva, Yoshihiko Ikeguchi, Emil Alexov

Publications

BACKGROUND AND SIGNIFICANCE:

Intellectual disability is a condition characterized by significant limitations in cognitive abilities and social/behavioral adaptive skills and is an important reason for pediatric, neurologic, and genetic referrals. Approximately 10% of protein-encoding genes on the X chromosome are implicated in intellectual disability, and the corresponding intellectual disability is termed X-linked ID (XLID). Although few mutations and a small number of families have been identified and XLID is rare, collectively the impact of XLID is significant because patients usually are unable to fully participate in society.

OBJECTIVE:

To reveal the molecular mechanisms of various intellectual disabilities and to suggest …

Enhancing Human Spermine Synthase Activity By Engineered Mutations, Zhe Zhang, Yueli Zheng, Margo Petukh, Anthony Pegg, Yoshihiko Ikeguchi, Emil Alexov

Publications

Spermine synthase (SMS) is an enzyme which function is to convert spermidine into spermine. It was shown that gene defects resulting in amino acid changes of the wild type SMS cause Snyder-Robinson syndrome, which is a mild-to-moderate mental disability associated with osteoporosis, facial asymmetry, thin habitus, hypotonia, and a nonspecific movement disorder. These disease-causing missense mutations were demonstrated, both in silico and in vitro, to affect the wild type function of SMS by either destabilizing the SMS dimer/monomer or directly affecting the hydrogen bond network of the active site of SMS. In contrast to these studies, here we report an …

A Method For Simulating Burr Type Iii And Type Xii Distributions Through L-Moments And L-Correlations, Mohan D. Pant, Todd C. Headrick

Publications

This paper derives the Burr Type III and Type XII family of distributions in the contexts of univariate 𝐿-moments and the 𝐿- correlations. Included is the development of a procedure for specifying nonnormal distributions with controlled degrees of 𝐿-skew, 𝐿-kurtosis, and 𝐿-correlations. The procedure can be applied in a variety of settings such as statistical modeling (e.g., forestry, fracture roughness, life testing, operational risk, etc.) and Monte Carlo or simulation studies. Numerical examples are provided to demonstrate that 𝐿-moment-based Burr distributions are superior to their conventional moment-based analogs in terms of estimation and distribution fitting. Evaluation of the proposed procedure …

Obstacles To Developing Digital Literacy On The Internet In Middle School Science Instruction, Jamie Colwell, Sarah Hunt-Barron, David Reinking

Publications

Obstacles, and instructional responses to them, that emerged in two middle school science classes during a formative experiment investigating Internet Reciprocal Teaching (IRT), an instructional intervention aimed at increasing digital literacy on the Internet, are reported in this manuscript. Analysis of qualitative data revealed that IRT enabled students to explain and demonstrate appropriate strategies for locating and evaluating information on the Internet when they were asked to do so. However, students did not use these strategies or they quickly abandoned them when working independently or in small groups during inquiry projects. Data revealed three obstacles that inhibited efforts to promote …

Design Of A Professional Practice Simulator For Educating And Motivating First-Year Engineering Students, Naomi C. Chesler, Golnaz Arastoopour Irgens, Cynthia M. D'Angelo, Elizabeth A. Bagley, David Williamson Shaffer

Publications

Increasingly, first-year engineering curricula incorporate design projects. However, the faculty and staff effort and physical resources required for the number of students enrolled can be daunting and affect the quality of instruction. To reduce these costs, ensure a high quality educational experience, and reduce variability in student outcomes that occur with individual design projects, we developed a simulation of engineering professional practice, NephroTex, in which teams of students are guided through multiple design-build-test cycles by a mentor in a virtual internship. Here we report on the design process for the virtual internship and results of testing with first-year engineering students …