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A Simulation Protocol For Exercise Physiology In Fontan Patients Using A Closed Loop Lumped-Parameter Model, Ethan Kung, Giancarlo Pennati, Francesco Migliavacca, Tian-Yen Hsia, Richard Figliola, Alison Marsden, Alessandro Giardini Jun 2014

A Simulation Protocol For Exercise Physiology In Fontan Patients Using A Closed Loop Lumped-Parameter Model, Ethan Kung, Giancarlo Pennati, Francesco Migliavacca, Tian-Yen Hsia, Richard Figliola, Alison Marsden, Alessandro Giardini

Publications

Background: Reduced exercise capacity is nearly universal among Fontan patients, though its etiology is not yet fully understood. While previous computational studies have attempted to model Fontan exercise, they did not fully account for global physiologic mechanisms nor directly compare results against clinical and physiologic data. Methods: In this study, we developed a protocol to simulate Fontan lower-body exercise using a closed-loop lumped-parameter model describing the entire circulation. We analyzed clinical exercise data from a cohort of Fontan patients, incorporated previous clinical findings from literature, quantified a comprehensive list of physiological changes during exercise, translated them into a computational model …

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Is Biofuel A Feasible Long-Term Chief Energy Source? A Global Perspective, Rajee Olaganathan, Aston Lee, Debra Tong, Mameegate Zheng Jun Cheston, Zack Ho Xuan Yi Jun 2014

Is Biofuel A Feasible Long-Term Chief Energy Source? A Global Perspective, Rajee Olaganathan, Aston Lee, Debra Tong, Mameegate Zheng Jun Cheston, Zack Ho Xuan Yi

Publications

This scientific paper examines the feasibility of officiating biofuels as the future chief energy source of the world. It weighs the pros and cons of the four different generations of biofuels that have been discovered over time, explaining how the raw materials used in each generation determines each individual level of long-term sustainability. It then further analyses both general advantages and disadvantages, comprising of economic, social, health and environmental impacts; giving the reader an unbiased perspective. Few case studies have also been reviewed to better understand the implications of drawing energy from biofuels, as well as the current state of …

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On The Dynamics, Thermodynamics, And Forecast Model Evaluation Of Two Snow-Burst Events In Southern Alberta, Shawn M. Milrad, John R. Gyakum, Kelly Lombardo, Eyad H. Atallah Jun 2014

On The Dynamics, Thermodynamics, And Forecast Model Evaluation Of Two Snow-Burst Events In Southern Alberta, Shawn M. Milrad, John R. Gyakum, Kelly Lombardo, Eyad H. Atallah

Publications

Two high-impact convective snowband events (‘‘snow bursts’’) that affected Calgary, Alberta, Canada, are examined to better understand the dynamics and thermodynamics of heavy snowbands not associated with lake effects or the cold conveyor belt of synoptic-scale cyclones. Such events are typically characterized by brief, but heavy, periods of snow; low visibilities; and substantial hazards to automobile and aviation interests. Previous literature on these events has been limited to a few case studies across North America, including near the leeside foothills of the U.S. Rockies. The large-scale dynamics and thermodynamics are investigated using the National Centers for Environmental Prediction (NCEP) North …

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Supplemental Multimedia Online Learning Tool (Smolt) In Engineering Education, Lulu Sun, Cassandra Gribbins, Ian T. Ferguson Jun 2014

Supplemental Multimedia Online Learning Tool (Smolt) In Engineering Education, Lulu Sun, Cassandra Gribbins, Ian T. Ferguson

Publications

This paper introduces the use of multimedia tools to create an online self-study environment to supplement the classroom instruction in engineering courses such as Graphical Communications. The topics in this course extend from hand sketching demonstrations to solid model creation using CAD software such as CATIA. Webcam, tablet PC, and Camtasia software were used to capture live examples and the recorded screencasts were posted in Blackboard. Supplemental Multimedia Online Learning Tools (SMOLT) provide students an efficient way to review the topics covered in the class, in that hand sketching and complex CAD models are often difficult to interpret through words …

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Reduction Of Transportation Greenhouse Gas Emissions To Mitigate Climate Change Impacts, Mary Snow, Richard Snow May 2014

Reduction Of Transportation Greenhouse Gas Emissions To Mitigate Climate Change Impacts, Mary Snow, Richard Snow

Publications

Weather affects almost all modes of transportation in a modern society, and likewise, transportation has an enormous impact on the weather. Transportation greenhouse gas emissions (GHG) impact climate change, which impacts transportation in return. Reduction of transportation impacts on climate change can mitigate the reverse climate change impacts on transportation. This paper examines the relationship between transportation and climate change and establishes prospective solutions to reduce transportation greenhouse gas emission impacts on climate change and mitigate the reverse climate change impacts on transportation.

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Three Moving Groups Detected In The Lamost Dr1 Archive, Zhao J. K., Zhao G., Y. Q. Chen, T. D. Oswalt, K. F. Tan, Y. Zhang May 2014

Three Moving Groups Detected In The Lamost Dr1 Archive, Zhao J. K., Zhao G., Y. Q. Chen, T. D. Oswalt, K. F. Tan, Y. Zhang

Publications

We analyze the kinematics of thick disk and halo stars observed by the Large Sky Area Multi-Object Fiber Spectroscopic Telescope. We have constructed a sample of 7993 F, G, and K nearby main-sequence stars (d < 2 kpc) with estimates of position (x, y, z) and space velocity (U, V, W) based on color and proper motion from the Sloan Digital Sky Survey DR9 catalog. Three “phase-space overdensities” are identified in (V,√U2 + 2V 2) with significance levels of σ > 3. Two of them (the Hyades–Pleiades stream …

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Thermospheric Dissipation Of Upward Propagating Gravity Wave Packets, C. J. Heale, J. B. Snively, M. P. Hickey, C. J. Ali May 2014

Thermospheric Dissipation Of Upward Propagating Gravity Wave Packets, C. J. Heale, J. B. Snively, M. P. Hickey, C. J. Ali

Publications

We use a nonlinear, fully compressible, two-dimensional numerical model to study the effects of dissipation on gravity wave packet spectra in the thermosphere. Numerical simulations are performed to excite gravity wave packets using either a time-dependent vertical body forcing at the bottom boundary or a specified initial wave perturbation. Three simulation case studies are performed to excite (1) a steady state monochromatic wave, (2) a spectrally broad wave packet, and (3) a quasi-monochromatic wave packet. In addition, we analyze (4) an initial condition simulation with an isothermal background. We find that, in cases where the wave is not continually forced, …

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Very Low Frequency Subionospheric Remote Sensing Of Thunderstorm-Driven Acoustic Waves In The Lower Ionosphere, R. A. Marshall, J. B. Snively May 2014

Very Low Frequency Subionospheric Remote Sensing Of Thunderstorm-Driven Acoustic Waves In The Lower Ionosphere, R. A. Marshall, J. B. Snively

Publications

"We present observations of narrowband subionospheric VLF transmitter signals on 20 March 2001, exhibiting coherent fluctuations of over 1 dB peak to peak. Spectral analysis shows that the fluctuations have periods of 1–4 min and are largely coherent. The subionospheric propagation path of the signal from Puerto Rico to Colorado passes over two regions of convective and lightning activity, as observed by GOES satellite imagery and National Lightning Detection Network lightning data. We suggest that these fluctuations are evidence of acoustic waves launched by the convective activity below, observed in the 80–90 km altitude range to which nighttime VLF subionospheric …

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The Nsf/Nih Effect: Surveying The Effect Of Data Management Requirements On Faculty, Sponsored Programs, And Institutional Repositories, Anne Diekema, Andrew Wesolek, Cheryl D. Walters May 2014

The Nsf/Nih Effect: Surveying The Effect Of Data Management Requirements On Faculty, Sponsored Programs, And Institutional Repositories, Anne Diekema, Andrew Wesolek, Cheryl D. Walters

Publications

The scholarly communication landscape is rapidly changing and nowhere is this more evident than in the field of data management. Mandates by major funding agencies, further expanded by executive order and pending legislation in 2013, require many research grant applicants to provide data management plans for preserving and making their research data openly available. However, do faculty researchers have the requisite skill sets and are their institutions providing the necessary infrastructure to comply with these mandates? To answer these questions, three groups were surveyed in 2012: research and teaching faculty, sponsored programs office staff, and institutional repository librarians. Survey results …

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A Novel P.Leu(381)Phe Mutation In Presenilin 1 Is Associated With Very Early Onset And Unusually Fast Progressing Dementia As Well As Lysosomal Inclusions Typically Seen In Kufs Disease, Natalia Dolzhanskaya, Michael A. Gonzalez, Fiorella Sperziani, Shannon Stefl, Jeffrey Messing, Guang Y. Wen, Emil Alexov, S Stephan Zuchner, Milen Velinov May 2014

A Novel P.Leu(381)Phe Mutation In Presenilin 1 Is Associated With Very Early Onset And Unusually Fast Progressing Dementia As Well As Lysosomal Inclusions Typically Seen In Kufs Disease, Natalia Dolzhanskaya, Michael A. Gonzalez, Fiorella Sperziani, Shannon Stefl, Jeffrey Messing, Guang Y. Wen, Emil Alexov, S Stephan Zuchner, Milen Velinov

Publications

Whole exome sequencing in a family with suspected dominant Kufs disease identified a novel Presenilin 1 mutation p.Leu(381)Phe in three brothers who, along with their father, developed progressive dementia and motor deficits in their early 30s. All affected relatives had unusually rapid disease progression (on average 3.6 years from disease onset to death). In silico analysis of mutation p.Leu(381)Phe predicted more detrimental effects when compared to the common Presenilin 1 mutation p.Glu(280)Ala. Electron microscopy study of peripheral fibroblast cells of the proband showed lysosomal inclusions typical for Kufs disease. However his brain autopsy demonstrated typical changes of Alzheimer disease.

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On The Modeling Of Polar Component Of Solvation Energy Using Smooth Gaussian-Based Dielectric Function, Lin Li, Chuan Li, Emil Alexov May 2014

On The Modeling Of Polar Component Of Solvation Energy Using Smooth Gaussian-Based Dielectric Function, Lin Li, Chuan Li, Emil Alexov

Publications

Traditional implicit methods for modeling electrostatics in biomolecules use a two-dielectric approach: a biomolecule is assigned low dielectric constant while the water phase is considered as a high dielectric constant medium. However, such an approach treats the biomolecule-water interface as a sharp dielectric border between two homogeneous dielectric media and does not account for inhomogeneous dielectric properties of the macromolecule as well. Recently we reported a new development, a smooth Gaussian-based dielectric function which treats the entire system, the solute and the water phase, as inhomogeneous dielectric medium (J Chem Theory Comput. 2013 Apr 9; 9(4): 2126-2136.). Here we examine …

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Teaching Hdfs/Mapreduce Systems Concepts To Undergraduates, Linh B. Ngo, Amy W. Apon, Edward B. Duffy May 2014

Teaching Hdfs/Mapreduce Systems Concepts To Undergraduates, Linh B. Ngo, Amy W. Apon, Edward B. Duffy

Publications

This paper presents the development of a Hadoop MapReduce module that has been taught in a course in distributed computing to upper undergraduate computer science students at Clemson University. The paper describes our teaching experiences and the feedback from the students over several semesters that have helped to shape the course. We provide suggested best practices for lecture materials, the computing platform, and the teaching methods. In addition, the computing platform and teaching methods can be extended to accommodate emerging technologies and modules for related courses.

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On The Electrostatic Properties Of Homodimeric Proteins, Brandon Campbell, Marharyta Petukh, Emil Alexov, Chuan Li May 2014

On The Electrostatic Properties Of Homodimeric Proteins, Brandon Campbell, Marharyta Petukh, Emil Alexov, Chuan Li

Publications

A large fraction of proteins function as homodimers, but it is not always clear why the dimerization is important for functionality since frequently each monomer possesses a distinctive active site. Recent work (PLoS Computational Biology, 9(2), e1002924) indicates that homodimerization may be important for forming an electrostatic funnel in the spermine synthase homodimer which guides changed substrates toward the active centers. This prompted us to investigate the electrostatic properties of a large set of homodimeric proteins and resulted in an observation that in a vast majority of the cases the dimerization indeed results in specific electrostatic features, although not necessarily …

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Chronic Beryllium Disease: Revealing The Role Of Beryllium Ion And Small Peptides Binding To Hla-Dp2, Marharyta Petukh, Bohua Wu, Shannon Stefl, Nick Smith, David Hyde-Volpe, Li Wang, Emil Alexov May 2014

Chronic Beryllium Disease: Revealing The Role Of Beryllium Ion And Small Peptides Binding To Hla-Dp2, Marharyta Petukh, Bohua Wu, Shannon Stefl, Nick Smith, David Hyde-Volpe, Li Wang, Emil Alexov

Publications

Chronic Beryllium (Be) Disease (CBD) is a granulomatous disorder that predominantly affects the lung. The CBD is caused by Be exposure of individuals carrying the HLA-DP2 protein of the major histocompatibility complex class II (MHCII). While the involvement of Be in the development of CBD is obvious and the binding site and the sequence of Be and peptide binding were recently experimentally revealed [1], the interplay between induced conformational changes and the changes of the peptide binding affinity in presence of Be were not investigated. Here we carry out in silico modeling and predict the Be binding to be within …

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Computational And Experimental Approaches To Reveal The Effects Of Single Nucleotide Polymorphisms With Respect To Disease Diagnostics, Tugba G. Kucukkal, Ye Yang, Susan C. Chapman, Weiguo Cao, Emil Alexov May 2014

Computational And Experimental Approaches To Reveal The Effects Of Single Nucleotide Polymorphisms With Respect To Disease Diagnostics, Tugba G. Kucukkal, Ye Yang, Susan C. Chapman, Weiguo Cao, Emil Alexov

Publications

DNA mutations are the cause of many human diseases and they are the reason for natural differences among individuals by affecting the structure, function, interactions, and other properties of DNA and expressed proteins. The ability to predict whether a given mutation is disease-causing or harmless is of great importance for the early detection of patients with a high risk of developing a particular disease and would pave the way for personalized medicine and diagnostics. Here we review existing methods and techniques to study and predict the effects of DNA mutations from three different perspectives: in silico, in vitro and …

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Empirical Modeling Of Residual Stress Profile In Machining Nickel-Based Superalloys Using The Sinusoidal Decay Function, D. Ulutan, Y. M. Arisoy, T. Ozel, Laine Mears May 2014

Empirical Modeling Of Residual Stress Profile In Machining Nickel-Based Superalloys Using The Sinusoidal Decay Function, D. Ulutan, Y. M. Arisoy, T. Ozel, Laine Mears

Publications

After machining nickel-based superalloys, tensile surface residual stresses can cause end-product issues such as fatigue failure. Modeling the residual stress profile is currently tedious and inaccurate. This study introduces a new method of understanding the residual stress profile in terms of quantifiable key measures: peak tensile stress at the surface, magnitude and depth of peak compressive stress, and depth at which residual stress becomes near-zero. Experiments in turning IN-100 and milling GTD-111 have been conducted and subsequent X-ray Diffraction measurements have been utilized to obtain residual stress profiles. Using a sinusoidal decay function fitted to measured residual stress profiles, these …

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Aircraft Access To System-Wide Information Management Infrastructure, Mohammad Moallemi, Remzi Seker, Mohamed Mahmoud, Jayson Clifford, John Pesce, Carlos Castro, Massood Towhidnejad, Jonathan Standley, Robert Klein May 2014

Aircraft Access To System-Wide Information Management Infrastructure, Mohammad Moallemi, Remzi Seker, Mohamed Mahmoud, Jayson Clifford, John Pesce, Carlos Castro, Massood Towhidnejad, Jonathan Standley, Robert Klein

Publications

Within the Federal Aviation Administration’s (FAA) NextGen project, System Wide Information Management (SWIM) program is the essential core in facilitating the collaborative access to the aviation information by various stakeholders. The Aircraft Access to SWIM (AAtS) initiative is an effort to connect the SWIM network to the aircraft to exchange the situational information between the aircraft and the National Airspace System (NAS). This paper summarizes the highlevel design and implementation of the AAtS infrastructure; namely the communication medium design, data management system, pilot peripheral, as well as the security of the data being exchanged and the performance of the entire …

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Implementing The Common Core’S Promise Of Bringing Statistical Curricula Into Line With Recommendations Of Nctm, Maa, & Gaise, Beverly Wood, Carl Clark May 2014

Implementing The Common Core’S Promise Of Bringing Statistical Curricula Into Line With Recommendations Of Nctm, Maa, & Gaise, Beverly Wood, Carl Clark

Publications

We plan to make a case for the necessity of GAISE-aligned college courses in order to prepare future teachers to teach in Common Core K-12 classrooms. Beginning with an overview of the parallel evolutions of Cobb/MAA suggestions - GAISE recommendations for teaching and NCTM process standards - Common Core mathematical practices, we will emphasize that we should be modeling what researchers continually conclude are best practices for teaching/learning across the K-16 continuum. We will provide some examples to illustrate classroom tasks that satisfy both GAISE and Common Core and hope to generate some discussion of other activities already used by …

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The White Dwarfs Within 25 Pc Of The Sun: Kinematics And Spectroscopic Subtypes, Edward M. Sion, J. B. Holberg, Terry D. Oswalt, George P. Mccook, Richard Wasatonic, Janine Myszka May 2014

The White Dwarfs Within 25 Pc Of The Sun: Kinematics And Spectroscopic Subtypes, Edward M. Sion, J. B. Holberg, Terry D. Oswalt, George P. Mccook, Richard Wasatonic, Janine Myszka

Publications

We present the fractional distribution of spectroscopic subtypes, range and distribution of surface temperatures, and kinematical properties of the white dwarfs (WDs) within 25 pc of the Sun. There is no convincing evidence of halo WDs in the total 25 pc sample of 224 WDs. There is also little to suggest the presence of genuine thick disk subcomponent members within 25 pc. It appears that the entire 25 pc sample likely belongs to the thin disk. We also find no significant kinematic differences with respect to spectroscopic subtypes. The total DA to non-DA ratio of the 25 pc sample is …

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Make Your Garden Grow: Designing A Physical Activity Estimation Improvement Game, Ashish Amresh, Leigh Small May 2014

Make Your Garden Grow: Designing A Physical Activity Estimation Improvement Game, Ashish Amresh, Leigh Small

Publications

We present a novel game and virtual world based application that is aimed at improving the physical activity estimation skills of parents. It has been well established that lack of proper estimation of preschool children’s activity levels may be one of the main causes for childhood obesity. Childhood obesity has several long term health effects ranging from cardio-vascular disease to type II diabetes and obese preschool children are at risk for later life. We have developed an application that caters to both the parent and the child and uses a virtual garden as a fledgling ecosystem controlled both by the …

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The Link Between Shocks, Turbulence And Magnetic Reconnection In Collisionless Plasmas, H. Karimabadi, V. Roytershteyn, H. X. Vu, Y. Omelchenko, J. Scudder, W. Daughton, A. Dimmock, Katariina (Heidi) Nykyri, Et Al. Apr 2014

The Link Between Shocks, Turbulence And Magnetic Reconnection In Collisionless Plasmas, H. Karimabadi, V. Roytershteyn, H. X. Vu, Y. Omelchenko, J. Scudder, W. Daughton, A. Dimmock, Katariina (Heidi) Nykyri, Et Al.

Publications

Global hybrid (electron fluid, kinetic ions) and fully kinetic simulations of the magnetosphere have been used to show surprising interconnection between shocks, turbulence and magnetic reconnection. In particular collisionless shocks with their reflected ions that can get upstream before retransmission can generate previously unforeseen phenomena in the post shocked flows: (i) formation of reconnecting current sheets and magnetic islands with sizes up to tens of ion inertial length. (ii) Generation of large scale low frequency electromagnetic waves that are compressed and amplified as they cross the shock. These 'wavefronts' maintain their integrity for tens of ion cyclotron times but eventually …

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Auroral Ionospheric F Region Density Cavity Formation And Evolution: Mica Campaign Results, M. Zettergren, K. A. Lynch, D. L. Hampton, M. Nicolls, B. Wright, Et Al. Apr 2014

Auroral Ionospheric F Region Density Cavity Formation And Evolution: Mica Campaign Results, M. Zettergren, K. A. Lynch, D. L. Hampton, M. Nicolls, B. Wright, Et Al.

Publications

Auroral ionospheric F region density depletions observed by PFISR (Poker Flat Incoherent Scatter Radar) during the MICA (Magnetosphere‐Ionosphere Coupling in the Alfvén Resonator) sounding rocket campaign are critically examined alongside complementary numerical simulations. Particular processes of interest include cavity formation due to intense frictional heating and Pedersen drifts, evolution in the presence of structured precipitation, and refilling due to impact ionization and downflows. Our analysis uses an ionospheric fluid model which solves conservation of mass, momentum, and energy equations for all major ionospheric species. These fluid equations are coupled to an electrostatic current continuity equation to self‐consistently describe auroral electric …

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An Alternate Proof Of The De Branges Theorem On Canonical Systems, Keshav R. Acharya Apr 2014

An Alternate Proof Of The De Branges Theorem On Canonical Systems, Keshav R. Acharya

Publications

The aim of this paper is to show that, in the limit circle case, the defect index of a symmetric relation induced by canonical systems, is constant on ₵. This provides an alternative proof of the De Branges theorem that the canonical systems with trH1 imply the limit point case. To this end, we discuss the spectral theory of a linear relation induced by a canonical system.

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Project Manager ‘Management Competency’ Vs. ‘Technical Competency’. Which Is More Important To Overall Project Management Success?, Barry Jon Bauer, Tracey M. Richardson, James W. Marion Jr Apr 2014

Project Manager ‘Management Competency’ Vs. ‘Technical Competency’. Which Is More Important To Overall Project Management Success?, Barry Jon Bauer, Tracey M. Richardson, James W. Marion Jr

Publications

Project managers apply multiple skills and competencies in the course of successfully delivering projects. Management and technical competencies represent two major competency categories associated with project management. In this study, the relationship between management and technical competency was investigated and a weak, yet positive correlation was observed as an outcome of this quantitative study.

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Book Review: Cosmic Dawn: The Search For The First Stars And Galaxies, T. D. Oswalt Apr 2014

Book Review: Cosmic Dawn: The Search For The First Stars And Galaxies, T. D. Oswalt

Publications

This document is Dr. Oswalt’s review of Cosmic Dawn : the Search for the First Stars and Galaxies by George Rhee, springer, 2013. 279p, 9781461478126 $39.99, 9781461478133 $29.99.

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One-Parameter Families Of Supersymmetric Isospectral Potentials From Riccati Solutions In Function Composition Form, Haret C. Rosu, S.C. Mancas, Pisin Chen Apr 2014

One-Parameter Families Of Supersymmetric Isospectral Potentials From Riccati Solutions In Function Composition Form, Haret C. Rosu, S.C. Mancas, Pisin Chen

Publications

In the context of supersymmetric quantum mechanics, we define a potential through a particular Riccati solution of the composition form (F∘f)(x)=F(f(x)) and obtain a generalized Mielnik construction of one-parameter isospectral potentials when we use the general Riccati solution. Some examples for special cases of F and f are given to illustrate the method. An interesting result is obtained in the case of a parametric double well potential generated by this method, for which it is shown that the parameter of the potential controls the heights of the localization probability in the two wells, and for certain values of the parameter …

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Synoptic Typing And Precursors Of Heavy Warm-Season Precipitation Events At Montreal, Québec, Shawn M. Milrad, Eyad H. Atallah, John R. Gyakum, Giselle Dookhie Apr 2014

Synoptic Typing And Precursors Of Heavy Warm-Season Precipitation Events At Montreal, Québec, Shawn M. Milrad, Eyad H. Atallah, John R. Gyakum, Giselle Dookhie

Publications

A precipitation climatology is compiled for warm-season events at Montreal, Québec, Canada, using 6-h precipitation data. A total of 1663 events are recorded and partitioned into three intensity categories (heavy, moderate, and light), based on percentile ranges. Heavy (top 10%) precipitation events (n = 166) are partitioned into four types, using a unique manual synoptic typing based on the divergence of Q-vector components. Type A is related to cyclones and strong synoptic-scale quasigeostrophic (QG) forcing for ascent, with high-θe air being advected into the Montreal region from the south. Types B and C are dominated by frontogenesis (mesoscale QG forcing …

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Coastal And Ocean Economic Summaries Of The Coastal States 2014, Pat Johnston Mar 2014

Coastal And Ocean Economic Summaries Of The Coastal States 2014, Pat Johnston

Publications

The following summaries of the ocean and coastal economies were prepared by the National Ocean Economics Program as a companion the State of the U.S. Ocean and Coastal Economies 2014. The U.S. report, its appendices, and these state summary reports are available on the NOEP website at www.OceanEconomics.org/download.

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Self-Adjoint Extension And Spectral Theory Of A Linear Relation In A Hilbert Space, Keshav R. Acharya Mar 2014

Self-Adjoint Extension And Spectral Theory Of A Linear Relation In A Hilbert Space, Keshav R. Acharya

Publications

The aim of this paper is to develop the conditions for a symmetric relation in a Hilbert space ℋ to have self-adjoint extensions in terms of defect indices and discuss some spectral theory of such linear relation.

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Assessing The Effect Of High Performance Computing Capabilities On Academic Research Output, Amy Apon, Linh B. Ngo, Michael E. Payne, Paul W. Wilson Mar 2014

Assessing The Effect Of High Performance Computing Capabilities On Academic Research Output, Amy Apon, Linh B. Ngo, Michael E. Payne, Paul W. Wilson

Publications

This paper uses nonparametric methods and some new results on hypothesis testing with nonparametric efficiency estimators and applies these to analyze the effect of locally-available high performance computing (HPC) resources on universities efficiency in producing research and other outputs. We find that locally-available HPC resources enhance the technical efficiency of research output in Chemistry, Civil Engineering, Physics, and History, but not in Computer Science, Economics, nor English; we find mixed results for Biology. Out research results provide a critical first step in a quantitative economic model for investments in HPC.

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