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Articles 4801 - 4830 of 5949
Full-Text Articles in Entire DC Network
Oscar Is A Collagen Receptor That Costimulates Osteoclastogenesis In Dap12-Deficient Humans And Mice, Alexander David Barrow, Marina Cella, Marco Colonna, Nicolas Raynal, Thomas Levin Anderson, David A. Slatter, Dominique Bihan, Nicholas Pugh, Taesoo Kim, Jaerang Rho, Takako Nedishi-Koga, Jean-Marie Delaisse, Hiroshi Takayanagi, Joseph Lorenzo, Et Al.
Oscar Is A Collagen Receptor That Costimulates Osteoclastogenesis In Dap12-Deficient Humans And Mice, Alexander David Barrow, Marina Cella, Marco Colonna, Nicolas Raynal, Thomas Levin Anderson, David A. Slatter, Dominique Bihan, Nicholas Pugh, Taesoo Kim, Jaerang Rho, Takako Nedishi-Koga, Jean-Marie Delaisse, Hiroshi Takayanagi, Joseph Lorenzo, Et Al.
Open Access Publications
No abstract provided.
Pml-Rara Can Increase Hematopoietic Self-Renewal Without Causing A Myeloproliferative Disease In Mice, John S. Welch, Wenlin Yuan, Timothy J. Ley
Pml-Rara Can Increase Hematopoietic Self-Renewal Without Causing A Myeloproliferative Disease In Mice, John S. Welch, Wenlin Yuan, Timothy J. Ley
Open Access Publications
No abstract provided.
Micrornas, An Active And Versatile Group In Cancers, Jeffrey Liu, Min Zheng, Ya-Ling Tang, Xin-Hua Liang, Qin Yang
Micrornas, An Active And Versatile Group In Cancers, Jeffrey Liu, Min Zheng, Ya-Ling Tang, Xin-Hua Liang, Qin Yang
Open Access Publications
No abstract provided.
Targeting Htlv-1 Activation Of Nfκb In Mouse Models And Atll Patients, Daniel A. Rauch, Lee Ratner
Targeting Htlv-1 Activation Of Nfκb In Mouse Models And Atll Patients, Daniel A. Rauch, Lee Ratner
Open Access Publications
No abstract provided.
Molecular Determinants Of Human T-Lymphotropic Virus Type 1 Transmission And Spread, Michael D. Lairmore, Rajaneesh Anupam, Nadine Bowden, Robyn Haines, Rashade A. H. Hayness Ii, Lee Ratner, Patrick L. Green
Molecular Determinants Of Human T-Lymphotropic Virus Type 1 Transmission And Spread, Michael D. Lairmore, Rajaneesh Anupam, Nadine Bowden, Robyn Haines, Rashade A. H. Hayness Ii, Lee Ratner, Patrick L. Green
Open Access Publications
No abstract provided.
Five Questions About Non-Mevalonate Isoprenoid Biosynthesis, Audrey R. Odom
Five Questions About Non-Mevalonate Isoprenoid Biosynthesis, Audrey R. Odom
Open Access Publications
No abstract provided.
Genetic Basis For In Vivo Daptomycin Resistance In Enterococci, Elizabeth Lobos, Erica Sodergren, George M. Weinstock, Et Al
Genetic Basis For In Vivo Daptomycin Resistance In Enterococci, Elizabeth Lobos, Erica Sodergren, George M. Weinstock, Et Al
Open Access Publications
No abstract provided.
Role Of Nadph Oxidase Versus Neutrophil Proteases In Antimicrobial Host Defense, R. Robert Vethanayagam, Nikolaos G. Almyroudis, Melissa J. Grimm, David C. Lewandowski, Christine T. N Pham, Timothy S. Blackwell, Ruta Petraitiene, Vidmantas Petraitis, Thomas J. Walsh, Constantin F. Urban, Brahm H. Segal
Role Of Nadph Oxidase Versus Neutrophil Proteases In Antimicrobial Host Defense, R. Robert Vethanayagam, Nikolaos G. Almyroudis, Melissa J. Grimm, David C. Lewandowski, Christine T. N Pham, Timothy S. Blackwell, Ruta Petraitiene, Vidmantas Petraitis, Thomas J. Walsh, Constantin F. Urban, Brahm H. Segal
Open Access Publications
No abstract provided.
Glucose And Fatty Acids Synergize To Promote B-Cell Apoptosis Through Activation Of Glycogen Synthase Kinase 3beta Independent Of Jnk Activation, Katsuya Tanabe, Yang Liu, Syed D. Hasan, Sara C. Martinez, Corentin Cras-Meneur, Cris M. Welling, Ernesto Bernal-Mizrachi, Yukio Tanizawa, Christopher J. Rhodes, Erik Zmuda, Tsonwin Hai, Nada A. Abumrad, M. Alan Permutt
Glucose And Fatty Acids Synergize To Promote B-Cell Apoptosis Through Activation Of Glycogen Synthase Kinase 3beta Independent Of Jnk Activation, Katsuya Tanabe, Yang Liu, Syed D. Hasan, Sara C. Martinez, Corentin Cras-Meneur, Cris M. Welling, Ernesto Bernal-Mizrachi, Yukio Tanizawa, Christopher J. Rhodes, Erik Zmuda, Tsonwin Hai, Nada A. Abumrad, M. Alan Permutt
Open Access Publications
No abstract provided.
Fine Mapping Of Genetic Variants In Bin1, Clu, Cr1 And Picalm For Association With Cerebrospinal Fluid Biomarkers For Alzheimer’S Disease, John S. K. Kauwe, Carlos Cruchaga, Celeste M. Karch, Brooke Sadler, Mo Lee, Kevin Mayo, Wayne Latu, Manti Su'a, Anne M. Fagan, David M. Holtzman, John C. Morris, Alzheimer's Disease Neuroimaging Initative, Alison M. Goate
Fine Mapping Of Genetic Variants In Bin1, Clu, Cr1 And Picalm For Association With Cerebrospinal Fluid Biomarkers For Alzheimer’S Disease, John S. K. Kauwe, Carlos Cruchaga, Celeste M. Karch, Brooke Sadler, Mo Lee, Kevin Mayo, Wayne Latu, Manti Su'a, Anne M. Fagan, David M. Holtzman, John C. Morris, Alzheimer's Disease Neuroimaging Initative, Alison M. Goate
Open Access Publications
No abstract provided.
Complete Genome Sequence Of Treponema Paraluiscuniculi, Strain Cuniculi A: The Loss Of Infectivity To Humans Is Associated With Genome Decay, David Smajs, Marie Zobanikova, Michal Strouhal, Darina Cejkova, Shannon Dugan-Rocha, Petra Pospisilova, Steven J. Norris, Tom Albert, Xiang Qin, Kym Hallsworth-Pepin, Christian Buhay, Donna M. Muzny, Lei Chen, Richard A. Gibbs, George M. Weinstock
Complete Genome Sequence Of Treponema Paraluiscuniculi, Strain Cuniculi A: The Loss Of Infectivity To Humans Is Associated With Genome Decay, David Smajs, Marie Zobanikova, Michal Strouhal, Darina Cejkova, Shannon Dugan-Rocha, Petra Pospisilova, Steven J. Norris, Tom Albert, Xiang Qin, Kym Hallsworth-Pepin, Christian Buhay, Donna M. Muzny, Lei Chen, Richard A. Gibbs, George M. Weinstock
Open Access Publications
No abstract provided.
Haploinsufficiency Of Human Apoe Reduces Amyloid Deposition In A Mouse Model Of Amyloid-Β Amyloidosis, Jungsu Kim, Hong Jiang, Seonha Park, Adam E.M. Eltorai, Floy R. Stewart, Hyejin Yoon, Jacob M. Basak, Mary Beth Finn, David M. Holtzman
Haploinsufficiency Of Human Apoe Reduces Amyloid Deposition In A Mouse Model Of Amyloid-Β Amyloidosis, Jungsu Kim, Hong Jiang, Seonha Park, Adam E.M. Eltorai, Floy R. Stewart, Hyejin Yoon, Jacob M. Basak, Mary Beth Finn, David M. Holtzman
Open Access Publications
No abstract provided.
Host Type I Ifn Signals Are Required For Antitumor Cd8+ T Cell Responses Through Cd8Α+ Dendritic Cells, Mercedes B. Fuertes, Aalok K. Kacha, Justin Kline, Seng-Ryong Woo, David M. Kranz, Kenneth M. Murphy, Thomas F. Gajewski
Host Type I Ifn Signals Are Required For Antitumor Cd8+ T Cell Responses Through Cd8Α+ Dendritic Cells, Mercedes B. Fuertes, Aalok K. Kacha, Justin Kline, Seng-Ryong Woo, David M. Kranz, Kenneth M. Murphy, Thomas F. Gajewski
Open Access Publications
No abstract provided.
A Nine Amino Acid Domain Is Essential For Mutant Prion Protein Toxicity, Laura Westergard, Jessie A. Turnbaugh, David A. Harris
A Nine Amino Acid Domain Is Essential For Mutant Prion Protein Toxicity, Laura Westergard, Jessie A. Turnbaugh, David A. Harris
Open Access Publications
No abstract provided.
Short-Term Plasticity Optimizes Synaptic Information Transmission, Ziv Rotman, Pan-Yue Deng, Vitaly A. Klyachko
Short-Term Plasticity Optimizes Synaptic Information Transmission, Ziv Rotman, Pan-Yue Deng, Vitaly A. Klyachko
Open Access Publications
No abstract provided.
Stathmin Is Required For Stability Of The Drosophila Neuromuscular Junction, Ethan R. Graf, Heather M. Heerssen, Christina M. Wright, Graeme W. Davis, Aaron Diantonio
Stathmin Is Required For Stability Of The Drosophila Neuromuscular Junction, Ethan R. Graf, Heather M. Heerssen, Christina M. Wright, Graeme W. Davis, Aaron Diantonio
Open Access Publications
No abstract provided.
Highwire Regulates Guidance Of Sister Axons In The Drosophila Mushroom Body, Jung Eun Shin, Aaron Diantonio
Highwire Regulates Guidance Of Sister Axons In The Drosophila Mushroom Body, Jung Eun Shin, Aaron Diantonio
Open Access Publications
No abstract provided.
The Role Of Attenuated Astrocyte Activation In Infantile Neuronal Ceroid Lipofuscinosis, Shannon L. Macauley, Milos Pekny, Mark S. Sands
The Role Of Attenuated Astrocyte Activation In Infantile Neuronal Ceroid Lipofuscinosis, Shannon L. Macauley, Milos Pekny, Mark S. Sands
Open Access Publications
No abstract provided.
Activator Protein 1 (Ap-1) Contributes To Epcam-Dependent Breast Cancer Invasion, Narenda V. Sankpal, John D. Mayfield, Mike W. Willman, Timothy P. Fleming, William E. Gillanders
Activator Protein 1 (Ap-1) Contributes To Epcam-Dependent Breast Cancer Invasion, Narenda V. Sankpal, John D. Mayfield, Mike W. Willman, Timothy P. Fleming, William E. Gillanders
Open Access Publications
No abstract provided.
Effects Of Human Immunodeficiency Virus And Metabolic Complications On Myocardial Nutrient Metabolism, Blood Flow, And Oxygen Consumption: A Cross-Sectional Analysis, W Todd Cade, Dominic N. Reeds, E Turner Overton, Pilar Herrero, Alan D. Waggoner, Victor G. Davila-Roman, Sherry Lassa-Claxton, Robert J. Gropler, Pablo F. Soto, Melissa J. Krauss, Kevin E. Yarasheski, Linda R. Peterson
Effects Of Human Immunodeficiency Virus And Metabolic Complications On Myocardial Nutrient Metabolism, Blood Flow, And Oxygen Consumption: A Cross-Sectional Analysis, W Todd Cade, Dominic N. Reeds, E Turner Overton, Pilar Herrero, Alan D. Waggoner, Victor G. Davila-Roman, Sherry Lassa-Claxton, Robert J. Gropler, Pablo F. Soto, Melissa J. Krauss, Kevin E. Yarasheski, Linda R. Peterson
Open Access Publications
No abstract provided.
Gender-Associated Genes In Filarial Nematodes Are Important For Reproduction And Potential Intervention Targets, Ben-Wen Li, Amy C. Rush, Dao-Jun Jiang, Makedonka Mitreva, Sahar Abubucker, Gary J. Weil
Gender-Associated Genes In Filarial Nematodes Are Important For Reproduction And Potential Intervention Targets, Ben-Wen Li, Amy C. Rush, Dao-Jun Jiang, Makedonka Mitreva, Sahar Abubucker, Gary J. Weil
Open Access Publications
No abstract provided.
Golgi Cells Operate As State-Specific Temporal Filters At The Input Stage Of The Cerebellar Cortex, Shane A. Heine, Stephen M. Highstein, Pablo M. Blazquez
Golgi Cells Operate As State-Specific Temporal Filters At The Input Stage Of The Cerebellar Cortex, Shane A. Heine, Stephen M. Highstein, Pablo M. Blazquez
Open Access Publications
Cerebellar processing of incoming information begins at the synapse between mossy fibers and granule cells, a synapse that is strongly controlled through Golgi cell inhibition. Thus, Golgi cells are uniquely positioned to control the flow of information into the cerebellar cortex and understanding their responses during behavior is essential to understanding cerebellar function. Here we show, for the first time, that Golgi cells express a unique oculomotor-related signal that can be used to provide state- and time-specific filtering of granule cell activity. We used newly established criteria to identify the unique electrophysiological signature of Golgi cells and recorded these neurons …
Membrane Anchoring Subunits Specify Selective Regulation Of Rgs9·Gbeta5 Gap Complex In Photoreceptor Neurons, Yan Cao, Alexander V. Kolesnikov, Ikuo Masuho, Vladimir J. Kefalov, Kirill A. Martemyanov
Membrane Anchoring Subunits Specify Selective Regulation Of Rgs9·Gbeta5 Gap Complex In Photoreceptor Neurons, Yan Cao, Alexander V. Kolesnikov, Ikuo Masuho, Vladimir J. Kefalov, Kirill A. Martemyanov
Open Access Publications
The RGS9·Gβ5 complex is the key regulator of neuronal G-protein signaling and shows remarkable selectivity of subunit composition. In retinal photoreceptors, RGS9·Gβ5 is bound to the membrane anchor R9AP and the complex regulates visual signaling. In the basal ganglia neurons, RGS9·Gβ5 is instead associated with a homologous protein, R7BP, and regulates reward circuit. Switching this selective subunit composition of the complex in rod photoreceptors allowed us to study the molecular underpinning of signaling specificity in diverse G-protein pathways. We have found that both membrane anchoring subunits play a conserved role in regulating protein levels of RGS9·Gβ5 and enhancing the ability …
Protein Turnover Of The Wallenda/Dlk Kinase Regulates A Retrograde Response To Axonal Injury, Xin Xiong, Xin Wang, Ronny Ewanek, Pavan Bhat, Aaron Diantonio, Catherine A. Collins
Protein Turnover Of The Wallenda/Dlk Kinase Regulates A Retrograde Response To Axonal Injury, Xin Xiong, Xin Wang, Ronny Ewanek, Pavan Bhat, Aaron Diantonio, Catherine A. Collins
Open Access Publications
No abstract provided.
What's New In Spine Surgery, Keith H. Bridwell, Paul A. Anderson, Scott D. Boden, Alexander R. Vaccaro, Jeffrey C. Wang
What's New In Spine Surgery, Keith H. Bridwell, Paul A. Anderson, Scott D. Boden, Alexander R. Vaccaro, Jeffrey C. Wang
Open Access Publications
No abstract provided.
Dynamic Contact Mechanics Of The Medial Meniscus As A Function Of Radial Tear, Repair, And Partial Meniscectomy, Asheesh Bedi, Natalie H. Kelly, Michael Baad, Alice J.S. Fox, Robert H. Brophy, Russell F. Warren, Suzanne A. Maher
Dynamic Contact Mechanics Of The Medial Meniscus As A Function Of Radial Tear, Repair, And Partial Meniscectomy, Asheesh Bedi, Natalie H. Kelly, Michael Baad, Alice J.S. Fox, Robert H. Brophy, Russell F. Warren, Suzanne A. Maher
Open Access Publications
No abstract provided.
Molecular Dissection Of I(A) In Cortical Pyramidal Neurons Reveals Three Distinct Components Encoded By Kv4.2, Kv4.3, And Kv1.4 Alpha-Subunits, Aaron J. Norris, Jeanne M. Nerbonne
Molecular Dissection Of I(A) In Cortical Pyramidal Neurons Reveals Three Distinct Components Encoded By Kv4.2, Kv4.3, And Kv1.4 Alpha-Subunits, Aaron J. Norris, Jeanne M. Nerbonne
Open Access Publications
The rapidly activating and inactivating voltage-gated K(+) (Kv) current, I(A), is broadly expressed in neurons and is a key regulator of action potential repolarization, repetitive firing, backpropagation (into dendrites) of action potentials, and responses to synaptic inputs. Interestingly, results from previous studies on a number of neuronal cell types, including hippocampal, cortical, and spinal neurons, suggest that macroscopic I(A) is composed of multiple components and that each component is likely encoded by distinct Kv channel alpha-subunits. The goals of the experiments presented here were to test this hypothesis and to determine the molecular identities of the Kv channel alpha-subunits that …
Relationship Of Tear Size And Location To Fatty Degeneration Of The Rotator Cuff, H. Mike Kim, Nirvikar Dahiya, Sharlene A. Teefey, Jay D. Keener, Leesa M. Galatz, Ken Yamaguchi
Relationship Of Tear Size And Location To Fatty Degeneration Of The Rotator Cuff, H. Mike Kim, Nirvikar Dahiya, Sharlene A. Teefey, Jay D. Keener, Leesa M. Galatz, Ken Yamaguchi
Open Access Publications
No abstract provided.
The Novel Endosomal Membrane Protein Ema Interacts With The Class C Vps-Hops Complex To Promote Endosomal Maturation, Sungsu Kim, Yogesh P. Wairkar, Richard W. Daniels, Aaron Diantonio
The Novel Endosomal Membrane Protein Ema Interacts With The Class C Vps-Hops Complex To Promote Endosomal Maturation, Sungsu Kim, Yogesh P. Wairkar, Richard W. Daniels, Aaron Diantonio
Open Access Publications
Endosomal maturation is critical for accurate and efficient cargo transport through endosomal compartments. Here we identify a mutation of the novel Drosophila gene, ema (endosomal maturation defective) in a screen for abnormal synaptic overgrowth and defective protein trafficking. Ema is an endosomal membrane protein required for trafficking of fluid-phase and receptor-mediated endocytic cargos. In the ema mutant, enlarged endosomal compartments accumulate as endosomal maturation fails, with early and late endosomes unable to progress into mature degradative late endosomes and lysosomes. Defective endosomal down-regulation of BMP signaling is responsible for the abnormal synaptic overgrowth. Ema binds to and genetically interacts with …
A Functional Metagenomic Approach For Expanding The Synthetic Biology Toolbox For Biomass Conversion, Morten O. A. Sommer, George M. Church, Gautam Dantas
A Functional Metagenomic Approach For Expanding The Synthetic Biology Toolbox For Biomass Conversion, Morten O. A. Sommer, George M. Church, Gautam Dantas
Open Access Publications
No abstract provided.