Open Access. Powered by Scholars. Published by Universities.®
- Discipline
- Keyword
-
- Humans (321)
- Animals (227)
- Female (168)
- Male (153)
- Mice (151)
-
- Middle Aged (67)
- Adult (64)
- Aged (60)
- Mice, Inbred C57BL (44)
- Disease Models, Animal (42)
- Signal Transduction (42)
- Mice, Knockout (40)
- COVID-19 (37)
- SARS-CoV-2 (32)
- Mutation (30)
- Brain (26)
- Young Adult (23)
- Adolescent (22)
- Aged, 80 and over (22)
- Child (22)
- Cells, Cultured (21)
- Neurons (21)
- Cell Line, Tumor (20)
- Mice, Transgenic (20)
- Child, Preschool (18)
- Protein Binding (17)
- Alzheimer Disease (16)
- Cell Line (16)
- Cell Proliferation (15)
- Gastrointestinal Microbiome (15)
Articles 4771 - 4800 of 5949
Full-Text Articles in Entire DC Network
Fibrocartilage Tissue Engineering: The Role Of The Stress Environment On Cell Morphology And Matrix Expression, Stavros Thomopoulos, Rosalina Das, Victor Birman, Lester Smith, Katherine Ku, Elliott L. Elson, Kenneth M. Pryse, Juan Pablo Marquez, Guy M. Genin
Fibrocartilage Tissue Engineering: The Role Of The Stress Environment On Cell Morphology And Matrix Expression, Stavros Thomopoulos, Rosalina Das, Victor Birman, Lester Smith, Katherine Ku, Elliott L. Elson, Kenneth M. Pryse, Juan Pablo Marquez, Guy M. Genin
Open Access Publications
No abstract provided.
Who Is Really At Risk? Identifying Risk Factors For Subthreshold And Full Syndrome Eating Disorders In A High-Risk Sample, C. Jacobi, E. Fittig, S. W. Bryson, D. Wilfley, H. C. Kraemer, C. Barr Taylor
Who Is Really At Risk? Identifying Risk Factors For Subthreshold And Full Syndrome Eating Disorders In A High-Risk Sample, C. Jacobi, E. Fittig, S. W. Bryson, D. Wilfley, H. C. Kraemer, C. Barr Taylor
Open Access Publications
No abstract provided.
Early Toxicity Predicts Long-Term Survival In High-Grade Glioma, Yaacov R. Lawrence, Meihua Wang, Adam Paul Dicker, David W. Andrews, Walter John Curran, Jeff Michael Michalski, Luis Souhami, Alfred K. Yung, Minesh Mehta
Early Toxicity Predicts Long-Term Survival In High-Grade Glioma, Yaacov R. Lawrence, Meihua Wang, Adam Paul Dicker, David W. Andrews, Walter John Curran, Jeff Michael Michalski, Luis Souhami, Alfred K. Yung, Minesh Mehta
Open Access Publications
No abstract provided.
Physical Activity And Risk Of Colon Adenoma: A Meta-Analysis, Kathleen Yaus Wolin, Yan Yan, Graham A. Colditz
Physical Activity And Risk Of Colon Adenoma: A Meta-Analysis, Kathleen Yaus Wolin, Yan Yan, Graham A. Colditz
Open Access Publications
No abstract provided.
Birth Characteristics And Childhood Carcinomas, Kimberly J. Johnson, Susan E. Carozza, Eric J. Chow, Erin E. Fox, Scott A. Horel, Colleen C. Mclaughlin, Beth A. Mueller, Susan E. Puumala, Peggy J. Reynolds, Julie Von Behren, Logan G. Spector
Birth Characteristics And Childhood Carcinomas, Kimberly J. Johnson, Susan E. Carozza, Eric J. Chow, Erin E. Fox, Scott A. Horel, Colleen C. Mclaughlin, Beth A. Mueller, Susan E. Puumala, Peggy J. Reynolds, Julie Von Behren, Logan G. Spector
Open Access Publications
No abstract provided.
Identification Of The Pgrmc1 Protein Complex As The Putative Sigma-2 Receptor Binding Site, Jinbin Xu, Chenbo Zeng, Wenhua Chu, Fenghui Pan, Justin M. Rothfuss, Fanjie Zhang, Zhude Tu, Dong Zhou, Dexing Zeng, Suwanna Vangveravong, Fabian Johnston, Dirk Spitzer, Katherine C. Chang, Richard S. Hotchkiss, William G. Hawkins, Robert H. Mach, Et Al
Identification Of The Pgrmc1 Protein Complex As The Putative Sigma-2 Receptor Binding Site, Jinbin Xu, Chenbo Zeng, Wenhua Chu, Fenghui Pan, Justin M. Rothfuss, Fanjie Zhang, Zhude Tu, Dong Zhou, Dexing Zeng, Suwanna Vangveravong, Fabian Johnston, Dirk Spitzer, Katherine C. Chang, Richard S. Hotchkiss, William G. Hawkins, Robert H. Mach, Et Al
Open Access Publications
No abstract provided.
A Vertebrate Case Study Of The Quality Of Assemblies Derived From Next-Generation Sequences, Liang Ye, Ladeana W. Hillier, Patrick Minx, Nay Thane, Devin P. Locke, John C. Martin, Lei Chen, Makedonka Mitreva, Jason R. Miller, Kevin V. Haub, David J. Dooling, Elaine R. Mardis, Richard K. Wilson, George M. Weinstock, Wesley C. Warren
A Vertebrate Case Study Of The Quality Of Assemblies Derived From Next-Generation Sequences, Liang Ye, Ladeana W. Hillier, Patrick Minx, Nay Thane, Devin P. Locke, John C. Martin, Lei Chen, Makedonka Mitreva, Jason R. Miller, Kevin V. Haub, David J. Dooling, Elaine R. Mardis, Richard K. Wilson, George M. Weinstock, Wesley C. Warren
Open Access Publications
No abstract provided.
The Development And Characterization Of A 60k Snp Chip For Chicken, Martin Am Groenen, Hendrik-Jan Megens, Yalda Zare, Wesley C. Warren, Ladeana W. Hillier, Richard Pma Crooijmans, Addie Vereijken, Ron Okimoto, Williams M. Muir, Hans H. Cheng
The Development And Characterization Of A 60k Snp Chip For Chicken, Martin Am Groenen, Hendrik-Jan Megens, Yalda Zare, Wesley C. Warren, Ladeana W. Hillier, Richard Pma Crooijmans, Addie Vereijken, Ron Okimoto, Williams M. Muir, Hans H. Cheng
Open Access Publications
No abstract provided.
Current Measures Of Metabolic Heterogeneity Within Cervical Cancer Do Not Predict Disease Outcome, Frank J. Brooks, Perry W. Grigsby
Current Measures Of Metabolic Heterogeneity Within Cervical Cancer Do Not Predict Disease Outcome, Frank J. Brooks, Perry W. Grigsby
Open Access Publications
No abstract provided.
Lineage-Specific Evolution Of The Vertebrate Otopetrin Gene Family Revealed By Comparative Genomic Analyses, Belen Hurle, Tomas Marques-Bonet, Francesca Antonacci, Inna Hughes, Joseph F. Ryan, Nisc Comparative Sequencing Program, Evan E. Eichler, David M. Ornitz, Eric D. Green
Lineage-Specific Evolution Of The Vertebrate Otopetrin Gene Family Revealed By Comparative Genomic Analyses, Belen Hurle, Tomas Marques-Bonet, Francesca Antonacci, Inna Hughes, Joseph F. Ryan, Nisc Comparative Sequencing Program, Evan E. Eichler, David M. Ornitz, Eric D. Green
Open Access Publications
No abstract provided.
Genome-Wide Identification Of Allele-Specific Expression (Ase) In Response To Marek’S Disease Virus Infection Using Next Generation Sequencing, Sean Maceachern, William M. Muir, Seth Crosby, Hans H. Cheng
Genome-Wide Identification Of Allele-Specific Expression (Ase) In Response To Marek’S Disease Virus Infection Using Next Generation Sequencing, Sean Maceachern, William M. Muir, Seth Crosby, Hans H. Cheng
Open Access Publications
No abstract provided.
Sox10 Directly Modulates Erbb3 Transcription Via An Intronic Neural Crest Enhancer, Megana K. Prasad, Xylena Reed, David U. Gorkin, Julia C. Cronin, Anthony R. Mcadow, Kristopher Chain, Chani J. Hodonsky, Erin A. Jones, John Svaren, Anthony Antonellis, Stephen L. Johnson, Stacie K. Loftus, William J. Pavan, Andrew S. Mccallion
Sox10 Directly Modulates Erbb3 Transcription Via An Intronic Neural Crest Enhancer, Megana K. Prasad, Xylena Reed, David U. Gorkin, Julia C. Cronin, Anthony R. Mcadow, Kristopher Chain, Chani J. Hodonsky, Erin A. Jones, John Svaren, Anthony Antonellis, Stephen L. Johnson, Stacie K. Loftus, William J. Pavan, Andrew S. Mccallion
Open Access Publications
No abstract provided.
Preclinical Modeling Of Combined Phosphatidylinositol-3-Kinase Inhibition With Endocrine Therapy For Estrogen Receptor-Positive Breast Cancer, Cesar G. Sanchez, Cynthia X. Ma, Robert J. Crowder, Therese Guintoli, Chanpheng Phommaly, Feng Gao, Li Lin, Matthew J. Ellis
Preclinical Modeling Of Combined Phosphatidylinositol-3-Kinase Inhibition With Endocrine Therapy For Estrogen Receptor-Positive Breast Cancer, Cesar G. Sanchez, Cynthia X. Ma, Robert J. Crowder, Therese Guintoli, Chanpheng Phommaly, Feng Gao, Li Lin, Matthew J. Ellis
Open Access Publications
No abstract provided.
The Loop-Less Tmcdc34 E2 Mutant Defective In Polyubiquitination In Vitro And In Vivo Supports Yeast Growth In A Manner Dependent On Ubp14 And Cka2, Agnieszka Lass, Ross Cocklin, Kenneth M. Scaglione, Michael Skowyra, Sergey Korolev, Mark Goebl, Dorota Skowyra
The Loop-Less Tmcdc34 E2 Mutant Defective In Polyubiquitination In Vitro And In Vivo Supports Yeast Growth In A Manner Dependent On Ubp14 And Cka2, Agnieszka Lass, Ross Cocklin, Kenneth M. Scaglione, Michael Skowyra, Sergey Korolev, Mark Goebl, Dorota Skowyra
Open Access Publications
No abstract provided.
Specific Sequence Determinants Of Mir-15/107 Microrna Gene Group Targets, Peter T. Nelson, Wang-Xia Wang, Guogen Mao, Bernard R. Wilfred, Kevin Xie, Mary H. Jennings, Zhen Gao, Xiaowei Wang
Specific Sequence Determinants Of Mir-15/107 Microrna Gene Group Targets, Peter T. Nelson, Wang-Xia Wang, Guogen Mao, Bernard R. Wilfred, Kevin Xie, Mary H. Jennings, Zhen Gao, Xiaowei Wang
Open Access Publications
No abstract provided.
Exploiting Oxytricha Trifallax Nanochromosomes To Screen For Non-Coding Rna Genes, Seolkyoung Jung, Estienne C. Swart, Patrick J. Minx, Vincent Magrini, Elaine R. Mardis, Laura F. Landweber, Sean R. Eddy
Exploiting Oxytricha Trifallax Nanochromosomes To Screen For Non-Coding Rna Genes, Seolkyoung Jung, Estienne C. Swart, Patrick J. Minx, Vincent Magrini, Elaine R. Mardis, Laura F. Landweber, Sean R. Eddy
Open Access Publications
No abstract provided.
Eisosome Proteins Assemble Into A Membrane Scaffold, Lena Karotki, Juha T. Huiskonen, Christopher J. Stefan, Natasza E. Ziółkowska, Robyn Roth, Michal A. Surma, Nevan J. Krogan, Scott D. Emr, John Heuser, Kay Grünewald, Tobias C. Walther
Eisosome Proteins Assemble Into A Membrane Scaffold, Lena Karotki, Juha T. Huiskonen, Christopher J. Stefan, Natasza E. Ziółkowska, Robyn Roth, Michal A. Surma, Nevan J. Krogan, Scott D. Emr, John Heuser, Kay Grünewald, Tobias C. Walther
Open Access Publications
Spatial organization of membranes into domains of distinct protein and lipid composition is a fundamental feature of biological systems. The plasma membrane is organized in such domains to efficiently orchestrate the many reactions occurring there simultaneously. Despite the almost universal presence of membrane domains, mechanisms of their formation are often unclear. Yeast cells feature prominent plasma membrane domain organization, which is at least partially mediated by eisosomes. Eisosomes are large protein complexes that are primarily composed of many subunits of two Bin-Amphiphysin-Rvs domain-containing proteins, Pil1 and Lsp1. In this paper, we show that these proteins self-assemble into higher-order structures and …
Autophagy In Antigen-Presenting Cells Results In Presentation Of Citrullinated Peptides To Cd4 T Cells, Jamie M. Ireland, Emil R. Unanue
Autophagy In Antigen-Presenting Cells Results In Presentation Of Citrullinated Peptides To Cd4 T Cells, Jamie M. Ireland, Emil R. Unanue
Open Access Publications
Antibody responses to citrullinated self-proteins are found in autoimmunities, particularly in rheumatoid arthritis, where they serve as a diagnostic indicator. We show here that processing of the protein hen egg-white lysozyme (HEL) resulted in citrullination of peptides presented on class II MHC molecules by antigen-presenting cells. The presentation of the citrullinated peptides but not of the unmodified peptides was associated with autophagy. Dendritic cells (DCs), macrophages, and thymic DCs presented citrullinated peptides constitutively. Their treatment with 3-methyladenine (3MA) blocked presentation of citrullinated HEL peptides, but presentation of unmodified peptides was not affected. Presentation of citrullinated peptides was not detected on …
A Genomic Storm In Critically Injured Humans, Wenzhong Xiao, Bernard H. Brownstein, Et Al
A Genomic Storm In Critically Injured Humans, Wenzhong Xiao, Bernard H. Brownstein, Et Al
Open Access Publications
No abstract provided.
Bop5 Mutations Reveal New Roles For The Ic138 Phosphoprotein In The Regulation Of Flagellar Motility And Asymmetric Waveforms, Kristyn E. Vanderwaal, Ryosuke Yamamoto, Ken-Ichi Wakabayashi, Laura Fox, Ritsu Kamiya, Susan K. Dutcher, Phillip V. Bayly, Winfield S. Sale, Mary E. Porter
Bop5 Mutations Reveal New Roles For The Ic138 Phosphoprotein In The Regulation Of Flagellar Motility And Asymmetric Waveforms, Kristyn E. Vanderwaal, Ryosuke Yamamoto, Ken-Ichi Wakabayashi, Laura Fox, Ritsu Kamiya, Susan K. Dutcher, Phillip V. Bayly, Winfield S. Sale, Mary E. Porter
Open Access Publications
No abstract provided.
New Tools And Methods For Direct Programmatic Access To The Dbsnp Relational Database, Scott F. Saccone, Jiaxi Quan, Gaurang Mehta, Raphael Bolze, Prasanth Thomas, Ewa Deelman, Jay A. Tischfield, John P. Rice
New Tools And Methods For Direct Programmatic Access To The Dbsnp Relational Database, Scott F. Saccone, Jiaxi Quan, Gaurang Mehta, Raphael Bolze, Prasanth Thomas, Ewa Deelman, Jay A. Tischfield, John P. Rice
Open Access Publications
No abstract provided.
Cd103+ Pulmonary Dendritic Cells Preferentially Acquire And Present Apoptotic Cell-Associated Antigen, A Nicole Desch, Gwendalyn J. Randolph, Kenneth Murphy, Emmanuel L. Gautier, Ross M. Kedl, Mireille H. Lahoud, Irina Caminschi, Ken Shortman, Peter M. Henson, Claudia V. Jakubzick
Cd103+ Pulmonary Dendritic Cells Preferentially Acquire And Present Apoptotic Cell-Associated Antigen, A Nicole Desch, Gwendalyn J. Randolph, Kenneth Murphy, Emmanuel L. Gautier, Ross M. Kedl, Mireille H. Lahoud, Irina Caminschi, Ken Shortman, Peter M. Henson, Claudia V. Jakubzick
Open Access Publications
Cells undergoing programmed cell death (apoptosis) are removed in situ by macrophages and dendritic cells (DCs) through a specialized form of phagocytosis (efferocytosis). In the lung, there are two primary DC subsets with the potential to migrate to the local lymph nodes (LNs) and initiate adaptive immune responses. In this study, we show that only CD103(+) DCs were able to acquire and transport apoptotic cells to the draining LNs and cross present apoptotic cell-associated antigen to CD8 T cells. In contrast, both the CD11b(hi) and the CD103(+) DCs were able to ingest and traffic latex beads or soluble antigen. CD103(+) …
Barth Syndrome Mutations That Cause Tafazzin Complex Lability, Steven M. Claypool, Kevin Whited, Santi Srijumnong, Xianlin Han, Carla M. Koehler
Barth Syndrome Mutations That Cause Tafazzin Complex Lability, Steven M. Claypool, Kevin Whited, Santi Srijumnong, Xianlin Han, Carla M. Koehler
Open Access Publications
Deficits in mitochondrial function result in many human diseases. The X-linked disease Barth syndrome (BTHS) is caused by mutations in the tafazzin gene TAZ1. Its product, Taz1p, participates in the metabolism of cardiolipin, the signature phospholipid of mitochondria. In this paper, a yeast BTHS mutant tafazzin panel is established, and 18 of the 21 tested BTHS missense mutations cannot functionally replace endogenous tafazzin. Four BTHS mutant tafazzins expressed at low levels are degraded by the intermembrane space AAA (i-AAA) protease, suggesting misfolding of the mutant polypeptides. Paradoxically, each of these mutant tafazzins assembles in normal protein complexes. Furthermore, in the …
Genome-Wide Identification And Quantification Of Cis- And Trans-Regulated Genes Responding To Marek’S Disease Virus Infection Via Analysis Of Allele-Specific Expression, Sean Maceachern, William M. Muir, Seth D. Crosby, Hans H. Cheng
Genome-Wide Identification And Quantification Of Cis- And Trans-Regulated Genes Responding To Marek’S Disease Virus Infection Via Analysis Of Allele-Specific Expression, Sean Maceachern, William M. Muir, Seth D. Crosby, Hans H. Cheng
Open Access Publications
No abstract provided.
The Tumor Suppressor Gene Trp53 Protects The Mouse Lens Against Posterior Subcapsular Cataracts And The Bmp Receptor Acvr1 Acts As A Tumor Suppressor In The Lens, Luke A. Wiley, Ramya Rajagopal, Lisa K. Dattilo, David C. Beebe
The Tumor Suppressor Gene Trp53 Protects The Mouse Lens Against Posterior Subcapsular Cataracts And The Bmp Receptor Acvr1 Acts As A Tumor Suppressor In The Lens, Luke A. Wiley, Ramya Rajagopal, Lisa K. Dattilo, David C. Beebe
Open Access Publications
No abstract provided.
Year In Review 2010: Critical Care- Neurocritical Care, Michael T. Scalfani, Michael N. Diringer
Year In Review 2010: Critical Care- Neurocritical Care, Michael T. Scalfani, Michael N. Diringer
Open Access Publications
No abstract provided.
Bcl3 Prevents Acute Inflammatory Lung Injury In Mice By Restraining Emergency Granulopoiesis, Daniel Kreisel, Seiichiro Sugimoto, Jeremy Tietjens, Jihong Zhu, Sumiharu Yamamoto, Alexander S. Krupnick, Ruaidhri J. Carmody, Andrew E. Gelman
Bcl3 Prevents Acute Inflammatory Lung Injury In Mice By Restraining Emergency Granulopoiesis, Daniel Kreisel, Seiichiro Sugimoto, Jeremy Tietjens, Jihong Zhu, Sumiharu Yamamoto, Alexander S. Krupnick, Ruaidhri J. Carmody, Andrew E. Gelman
Open Access Publications
No abstract provided.
Notch1 Loss Of Heterozygosity Causes Vascular Tumors And Lethal Hemorrhage In Mice, Zhenyi Liu, Ahu Turkoz, Erin N. Jackson, Joseph C. Corbo, John A. Engelbach, Joel R. Garbow, David R. Piwnica-Worms, Raphael Kopan
Notch1 Loss Of Heterozygosity Causes Vascular Tumors And Lethal Hemorrhage In Mice, Zhenyi Liu, Ahu Turkoz, Erin N. Jackson, Joseph C. Corbo, John A. Engelbach, Joel R. Garbow, David R. Piwnica-Worms, Raphael Kopan
Open Access Publications
No abstract provided.
Cd2ap In Mouse And Human Podocytes Controls A Proteolytic Program That Regulates Cytoskeletal Structure And Cellular Survival, Andrey S. Shaw, Suma Yaddanapudi, Mehmet M. Altintas, Andreas D. Kistler, Isabel Fernandez, Clemens C. Moller, Changli Wei, Vasil Peev, Jan B. Flesche, Anna-Lena Forst, Jing Li, Jaakko Patrakka, Zhijie Xiao, Florian Grahammer, Et Al.
Cd2ap In Mouse And Human Podocytes Controls A Proteolytic Program That Regulates Cytoskeletal Structure And Cellular Survival, Andrey S. Shaw, Suma Yaddanapudi, Mehmet M. Altintas, Andreas D. Kistler, Isabel Fernandez, Clemens C. Moller, Changli Wei, Vasil Peev, Jan B. Flesche, Anna-Lena Forst, Jing Li, Jaakko Patrakka, Zhijie Xiao, Florian Grahammer, Et Al.
Open Access Publications
No abstract provided.
Rhoa Protects The Mouse Heart Against Ischemia/Reperfusion Injury, Sunny Yang Xiang, Davy Vanhoutte, Dominic P. Del Re, Nicole H. Purcell, Haiyun Ling, Indroneal Banerjee, Julie Bossuyt, Richard A. Lang, Yi Zheng, Scot J. Matkovich, Shigeki Miyamoto, Jeffrey D. Molkentin, Gerald W. Dorn Ii, Joan Heller Brown
Rhoa Protects The Mouse Heart Against Ischemia/Reperfusion Injury, Sunny Yang Xiang, Davy Vanhoutte, Dominic P. Del Re, Nicole H. Purcell, Haiyun Ling, Indroneal Banerjee, Julie Bossuyt, Richard A. Lang, Yi Zheng, Scot J. Matkovich, Shigeki Miyamoto, Jeffrey D. Molkentin, Gerald W. Dorn Ii, Joan Heller Brown
Open Access Publications
No abstract provided.