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Articles 1081 - 1110 of 11655
Full-Text Articles in Entire DC Network
Proportion And Number Of Upper-Extremity Musculoskeletal Disorders Attributable To The Combined Effect Of Biomechanical And Psychosocial Risk Factors In A Working Population, Aboubakari Nambiema, Julie Bodin, Susan Stock, Agnès Aublet-Cuvelier, Alexis Descatha, Bradley Evanoff, Yves Roquelaure
Proportion And Number Of Upper-Extremity Musculoskeletal Disorders Attributable To The Combined Effect Of Biomechanical And Psychosocial Risk Factors In A Working Population, Aboubakari Nambiema, Julie Bodin, Susan Stock, Agnès Aublet-Cuvelier, Alexis Descatha, Bradley Evanoff, Yves Roquelaure
Open Access Publications
The objective of this paper is to assess the combined effect of occupational biomechanical and psychosocial risk factors on the incidence of work-related upper-extremity musculoskeletal disorders (UEMSDs) and estimate the proportion and number of incident cases attributable to these risk factors in a working population. Using data from the French COSALI (COhorte des SAlariés LIgériens) cohort (enrolment phase: 2002-2005; follow-up phase: 2007-2010), a complete case analysis including 1246 workers (59% men, mean age: 38 years ± 8.6 at baseline) was performed. All participants underwent a standardized clinical examination at enrolment and 1611 workers were re-examined at follow-up. Population attributable fractions …
The Position Of Single-Base Deletions In The Vntr Sequence Of The Carboxyl Ester Lipase (Cel) Gene Determines Proteotoxicity, Anny Gravdal, Xunjun Xiao, Miriam Cnop, Khadija El Jellas, Stefan Johansson, Pål R. Njølstad, Mark E. Lowe, Bente B. Johansson, Anders Molven, Karianne Fjeld
The Position Of Single-Base Deletions In The Vntr Sequence Of The Carboxyl Ester Lipase (Cel) Gene Determines Proteotoxicity, Anny Gravdal, Xunjun Xiao, Miriam Cnop, Khadija El Jellas, Stefan Johansson, Pål R. Njølstad, Mark E. Lowe, Bente B. Johansson, Anders Molven, Karianne Fjeld
Open Access Publications
No abstract provided.
High-Fat Diet Activates Liver Ipla2Γ Generating Eicosanoids That Mediate Metabolic Stress, Sung Ho Moon, Beverly Gibson Dilthey, Xinping Liu, Shaoping Guan, Harold F. Sims, Richard W. Gross
High-Fat Diet Activates Liver Ipla2Γ Generating Eicosanoids That Mediate Metabolic Stress, Sung Ho Moon, Beverly Gibson Dilthey, Xinping Liu, Shaoping Guan, Harold F. Sims, Richard W. Gross
Open Access Publications
No abstract provided.
Acanthamoeba Keratitis, Pathology, Diagnosis And Treatment, Nicholas Fanselow, Nadia Sirajuddin, Xiao-Tang Yin, Andrew J W Huang, Patrick M Stuart
Acanthamoeba Keratitis, Pathology, Diagnosis And Treatment, Nicholas Fanselow, Nadia Sirajuddin, Xiao-Tang Yin, Andrew J W Huang, Patrick M Stuart
Open Access Publications
No abstract provided.
Tumor Long Interspersed Nucleotide Element-1 (Line-1) Hypomethylation In Relation To Age Of Colorectal Cancer Diagnosis And Prognosis, Naohiko Akimoto, Yin Cao, Et Al
Tumor Long Interspersed Nucleotide Element-1 (Line-1) Hypomethylation In Relation To Age Of Colorectal Cancer Diagnosis And Prognosis, Naohiko Akimoto, Yin Cao, Et Al
Open Access Publications
Evidence indicates the pathogenic role of epigenetic alterations in early-onset colorectal cancers diagnosed before age 50. However, features of colorectal cancers diagnosed at age 50-54 (hereafter referred to as "intermediate-onset") remain less known. We hypothesized that tumor long interspersed nucleotide element-1 (LINE-1) hypomethylation might be increasingly more common with decreasing age of colorectal cancer diagnosis. In 1356 colorectal cancers, including 28 early-onset and 66 intermediate-onset cases, the tumor LINE-1 methylation level measured by bisulfite-PCR-pyrosequencing (scaled 0 to 100) showed a mean of 63.6 (standard deviation (SD) 10.1). The mean tumor LINE-1 methylation level decreased with decreasing age (mean 64.7 (SD …
Beyond The Gastrointestinal Tract: The Emerging And Diverse Tissue Tropisms Of Astroviruses, Andrew B Janowski
Beyond The Gastrointestinal Tract: The Emerging And Diverse Tissue Tropisms Of Astroviruses, Andrew B Janowski
Open Access Publications
Astroviruses are single stranded, positive-sense RNA viruses that have been historically associated with diseases of the gastrointestinal tract of vertebrates, including humans. However, there is now a multitude of evidence demonstrating the capacity of these viruses to cause extraintestinal diseases. The most striking causal relationship is neurological diseases in humans, cattle, pigs, and other mammals, caused by astrovirus infection. Astroviruses have also been associated with disseminated infections, localized disease of the liver or kidneys, and there is increasing evidence suggesting a potential tropism to the respiratory tract. This review will discuss the current understanding of the tissue tropisms for astroviruses …
4Β-Hydroxycholesterol Is A Prolipogenic Factor That Promotes Srebp1c Expression And Activity Through The Liver X Receptor, Ofer Moldavski, Peter-James H. Zushin, Charles A. Berdan, Robert J. Van Eijkeren, Xuntian Jiang, Mingxing Qian, Daniel S. Ory, Douglas F. Covey, Daniel K. Nomura, Andreas Stahl, Ethan J. Weiss, Roberto Zoncu
4Β-Hydroxycholesterol Is A Prolipogenic Factor That Promotes Srebp1c Expression And Activity Through The Liver X Receptor, Ofer Moldavski, Peter-James H. Zushin, Charles A. Berdan, Robert J. Van Eijkeren, Xuntian Jiang, Mingxing Qian, Daniel S. Ory, Douglas F. Covey, Daniel K. Nomura, Andreas Stahl, Ethan J. Weiss, Roberto Zoncu
Open Access Publications
No abstract provided.
Generation Of A Gene-Corrected Human Isogenic Ipsc Line From An Alzheimer’S Disease Ipsc Line Carrying The London Mutation In App (V717i), Damian Hernandez, Stephanie Morgan Schlicht, Maciej Daniszewski, Celeste M. Karch, Dominantly Inherited Network (Dian), Alison M. Goate, Alice Pebay
Generation Of A Gene-Corrected Human Isogenic Ipsc Line From An Alzheimer’S Disease Ipsc Line Carrying The London Mutation In App (V717i), Damian Hernandez, Stephanie Morgan Schlicht, Maciej Daniszewski, Celeste M. Karch, Dominantly Inherited Network (Dian), Alison M. Goate, Alice Pebay
Open Access Publications
No abstract provided.
Familial Lipomas Without Classic Neurofibromatosis-1 Caused By A Missense Germline Nf1 Mutation, Erika Ramirez, Stephanie M. Morris, Tychele N. Turner, David H. Gutmann
Familial Lipomas Without Classic Neurofibromatosis-1 Caused By A Missense Germline Nf1 Mutation, Erika Ramirez, Stephanie M. Morris, Tychele N. Turner, David H. Gutmann
Open Access Publications
No abstract provided.
Cytokine Profiling In Plasma From Patients With Brain Tumors Versus Healthy Individuals Using 2 Different Multiplex Immunoassay Platforms, Diane Elizabeth Bender, Maximilian O. Schaettler, Kathleen C.F. Sheehan, Tanner M. Johanns, Gavin P. Dunn
Cytokine Profiling In Plasma From Patients With Brain Tumors Versus Healthy Individuals Using 2 Different Multiplex Immunoassay Platforms, Diane Elizabeth Bender, Maximilian O. Schaettler, Kathleen C.F. Sheehan, Tanner M. Johanns, Gavin P. Dunn
Open Access Publications
No abstract provided.
Resting-State Functional Connectivity Disruption As A Pathological Biomarker In Autosomal Dominant Alzheimer Disease, Robert X. Smith, Jeremy F. Strain, Aaron Tanenbaum, Anne M. Fagan, Jason Hassenstab, Eric Mcdade, Suzanne E. Schindler, Brian A. Gordon, Chengjie Xiong, Celeste Karch, David M. Holtzman, Daniel S. Marcus, John C. Morris, Tammie L.S. Benzinger, Randall J. Bateman, Beau M. Ances, Et Al.
Resting-State Functional Connectivity Disruption As A Pathological Biomarker In Autosomal Dominant Alzheimer Disease, Robert X. Smith, Jeremy F. Strain, Aaron Tanenbaum, Anne M. Fagan, Jason Hassenstab, Eric Mcdade, Suzanne E. Schindler, Brian A. Gordon, Chengjie Xiong, Celeste Karch, David M. Holtzman, Daniel S. Marcus, John C. Morris, Tammie L.S. Benzinger, Randall J. Bateman, Beau M. Ances, Et Al.
Open Access Publications
No abstract provided.
Brd4-Bound Enhancers Drive Cell-Intrinsic Sex Differences In Glioblastoma, Najla Kfoury, Zongtai Qi, Briana C. Prager, Michael N. Wilkinson, Lauren Broestl, Kristopher C. Berrett, Arnav Moudgil, Sumithra Sankararaman, Xuhua Chen, Jason Gertz, Jeremy N. Rich, Robi D. Mitra, Joshua B. Rubin
Brd4-Bound Enhancers Drive Cell-Intrinsic Sex Differences In Glioblastoma, Najla Kfoury, Zongtai Qi, Briana C. Prager, Michael N. Wilkinson, Lauren Broestl, Kristopher C. Berrett, Arnav Moudgil, Sumithra Sankararaman, Xuhua Chen, Jason Gertz, Jeremy N. Rich, Robi D. Mitra, Joshua B. Rubin
Open Access Publications
No abstract provided.
Recent Developments In Devices Used For Gastrointestinal Endoscopy Sedation, Basavana Goudra, Gowri Gouda, Preet Mohinder Singh
Recent Developments In Devices Used For Gastrointestinal Endoscopy Sedation, Basavana Goudra, Gowri Gouda, Preet Mohinder Singh
Open Access Publications
No abstract provided.
The Transcriptional Landscape Of Shh Medulloblastoma, Patryk Skowron, Joshua B. Rubin, Et Al.
The Transcriptional Landscape Of Shh Medulloblastoma, Patryk Skowron, Joshua B. Rubin, Et Al.
Open Access Publications
No abstract provided.
Apathy, Cognitive Impairment, And Social Support Contribute To Participation In Cognitively Demanding Activities Poststroke, Amy Ho, Marjorie L. Nicholas, Chaitali Dagli, Lisa Tabor Connor
Apathy, Cognitive Impairment, And Social Support Contribute To Participation In Cognitively Demanding Activities Poststroke, Amy Ho, Marjorie L. Nicholas, Chaitali Dagli, Lisa Tabor Connor
Open Access Publications
No abstract provided.
Toward A More Comprehensive Assessment Of School Age Children With Hemiplegic Cerebral Palsy, Catherine R. Hoyt, Sarah K. Sherman, Shelby K. Brown, Dillan J. Newbold, Ryland L. Miller, Andrew N. Van, Joshua S. Shimony, Mario Ortega, Annie L. Nguyen, Bradley L. Schlaggar, Nico U.F. Dosenbach
Toward A More Comprehensive Assessment Of School Age Children With Hemiplegic Cerebral Palsy, Catherine R. Hoyt, Sarah K. Sherman, Shelby K. Brown, Dillan J. Newbold, Ryland L. Miller, Andrew N. Van, Joshua S. Shimony, Mario Ortega, Annie L. Nguyen, Bradley L. Schlaggar, Nico U.F. Dosenbach
Open Access Publications
No abstract provided.
Cisplatin +/− Rucaparib After Preoperative Chemotherapy In Patients With Triple-Negative Or Brca Mutated Breast Cancer, Maitri Kalra, Yang Tong, David R. Jones, Tom Walsh, Michael A. Danso, Cynthia X. Ma, Paula Silverman, Mary-Claire King, Sunil S. Badve, Susan M. Perkins, Kathy D. Miller
Cisplatin +/− Rucaparib After Preoperative Chemotherapy In Patients With Triple-Negative Or Brca Mutated Breast Cancer, Maitri Kalra, Yang Tong, David R. Jones, Tom Walsh, Michael A. Danso, Cynthia X. Ma, Paula Silverman, Mary-Claire King, Sunil S. Badve, Susan M. Perkins, Kathy D. Miller
Open Access Publications
No abstract provided.
Contribution Of Noncanonical Antigens To Virulence And Adaptive Immunity In Human Infection With Enterotoxigenic E. Coli, F.M. Kuhlmann, R.O. Laine, S. Afrin, R. Nakajima, M. Akhtar, T. Vickers, K. Parker, N.N. Nizam, V. Grigura, C.W. Goss, P. L. Felgner, D. A. Rasko, F. Qadri, J. M. Fleckenstein
Contribution Of Noncanonical Antigens To Virulence And Adaptive Immunity In Human Infection With Enterotoxigenic E. Coli, F.M. Kuhlmann, R.O. Laine, S. Afrin, R. Nakajima, M. Akhtar, T. Vickers, K. Parker, N.N. Nizam, V. Grigura, C.W. Goss, P. L. Felgner, D. A. Rasko, F. Qadri, J. M. Fleckenstein
Open Access Publications
No abstract provided.
Dnmt3a Deficiency In The Skin Causes Focal, Canonical Dna Hypomethylation And A Cellular Proliferation Phenotype, David Y. Chen, Ian M. Ferguson, Krista A. Braun, Leslie A. Sutton, Nichole M. Helton, Sai Mukund Ramakrishnan, Amanda M. Smith, Christopher A. Miller, Timothy J. Ley
Dnmt3a Deficiency In The Skin Causes Focal, Canonical Dna Hypomethylation And A Cellular Proliferation Phenotype, David Y. Chen, Ian M. Ferguson, Krista A. Braun, Leslie A. Sutton, Nichole M. Helton, Sai Mukund Ramakrishnan, Amanda M. Smith, Christopher A. Miller, Timothy J. Ley
Open Access Publications
No abstract provided.
Calcium Carbonate Nanoparticles Stimulate Cancer Cell Reprogramming To Suppress Tumor Growth And Invasion In An Organ‑On‑A‑Chip System, Sandra F. Lam, Kevin W. Bishop, Rachel Mintz, Lei Fang, Samuel Achilefu
Calcium Carbonate Nanoparticles Stimulate Cancer Cell Reprogramming To Suppress Tumor Growth And Invasion In An Organ‑On‑A‑Chip System, Sandra F. Lam, Kevin W. Bishop, Rachel Mintz, Lei Fang, Samuel Achilefu
Open Access Publications
No abstract provided.
Single-Cell Analyses Of Crohn’S Disease Tissues Reveal Intestinal Intraepithelial T Cells Heterogeneity And Altered Subset Distributions, Natalia Jaeger, Ramya Gamini, Marina Cella, Jorge L. Schettini, Mattia Bugatti, Shanrong Zhao, Charles V. Rosadini, Ekaterina Esaulova, Blanda Di Luccia, Baylee Kinnett, William Vermi, Maxim N. Artyomov, Thomas A. Wynn, Ramnik J. Xavier, Scott A. Jelinsky, Marco Colonna
Single-Cell Analyses Of Crohn’S Disease Tissues Reveal Intestinal Intraepithelial T Cells Heterogeneity And Altered Subset Distributions, Natalia Jaeger, Ramya Gamini, Marina Cella, Jorge L. Schettini, Mattia Bugatti, Shanrong Zhao, Charles V. Rosadini, Ekaterina Esaulova, Blanda Di Luccia, Baylee Kinnett, William Vermi, Maxim N. Artyomov, Thomas A. Wynn, Ramnik J. Xavier, Scott A. Jelinsky, Marco Colonna
Open Access Publications
No abstract provided.
The Impact Of Covid-19 On Dual-Physician Couples: A Disproportionate Burden On Women Physicians, Andrea Soares, Prashanth Thakker, Elena Deych, Shikha Jain, Rakhee K. Bhayani
The Impact Of Covid-19 On Dual-Physician Couples: A Disproportionate Burden On Women Physicians, Andrea Soares, Prashanth Thakker, Elena Deych, Shikha Jain, Rakhee K. Bhayani
Open Access Publications
No abstract provided.
Monocyte Progenitors Give Rise To Multinucleated Giant Cells, Anne Kathrin Lösslein, Micah D. Dunlap, Shabaana A. Khader, Et Al.
Monocyte Progenitors Give Rise To Multinucleated Giant Cells, Anne Kathrin Lösslein, Micah D. Dunlap, Shabaana A. Khader, Et Al.
Open Access Publications
No abstract provided.
Old Vaccines For New Infections: Exploiting Innate Immunity To Control Covid-19 And Prevent Future Pandemics, Konstantin Chumakov, Michael S. Avidan, Christine S. Benn, Stefano M. Bertozzi, Lawrence Blatt, Angela Y. Chang, Dean T. Jamison, Shabaana A. Khader, Shyam Kottilil, Mihai G. Netea, Annie Sparrow, Robert C. Gallo
Old Vaccines For New Infections: Exploiting Innate Immunity To Control Covid-19 And Prevent Future Pandemics, Konstantin Chumakov, Michael S. Avidan, Christine S. Benn, Stefano M. Bertozzi, Lawrence Blatt, Angela Y. Chang, Dean T. Jamison, Shabaana A. Khader, Shyam Kottilil, Mihai G. Netea, Annie Sparrow, Robert C. Gallo
Open Access Publications
No abstract provided.
The Sars-Cov-2 Nucleocapsid Protein Is Dynamic, Disordered, And Phase Separates With Rna, Jasmine Cubuk, Jhullian J. Alston, J. Jeremías Incicco, Sukrit Singh, Melissa D. Stuchell-Brereton, Michael D. Ward, Maxwell I. Zimmerman, Neha Vithani, Daniel Griffith, Jason A. Wagoner, Gregory R. Bowman, Kathleen B. Hall, Andrea Soranno, Alex S. Holehouse
The Sars-Cov-2 Nucleocapsid Protein Is Dynamic, Disordered, And Phase Separates With Rna, Jasmine Cubuk, Jhullian J. Alston, J. Jeremías Incicco, Sukrit Singh, Melissa D. Stuchell-Brereton, Michael D. Ward, Maxwell I. Zimmerman, Neha Vithani, Daniel Griffith, Jason A. Wagoner, Gregory R. Bowman, Kathleen B. Hall, Andrea Soranno, Alex S. Holehouse
Open Access Publications
No abstract provided.
Crispri Screens Reveal A Dna Methylation-Mediated 3d Genome Dependent Causal Mechanism In Prostate Cancer, Musaddeque Ahmed, Hyung Joo Lee, Ting Wang, Et Al.
Crispri Screens Reveal A Dna Methylation-Mediated 3d Genome Dependent Causal Mechanism In Prostate Cancer, Musaddeque Ahmed, Hyung Joo Lee, Ting Wang, Et Al.
Open Access Publications
No abstract provided.
Paroxysmal Kinesigenic Dyskinesia In Twins With Chromosome 16p11.2 Duplication Syndrome, Keisuke Ueda, Marwan Shinawi, Toni S. Pearson
Paroxysmal Kinesigenic Dyskinesia In Twins With Chromosome 16p11.2 Duplication Syndrome, Keisuke Ueda, Marwan Shinawi, Toni S. Pearson
Open Access Publications
No abstract provided.
Chromosome Xq23 Is Associated With Lower Atherogenic Lipid Concentrations And Favorable Cardiometabolic Indices, Pradeep Natarajan, Lucinda Antonacci-Fulton, Susan K. Dutcher, D.C. Rao, C. Charles Gu, Karen Schwander, Yun Ju Sung, Et Al.
Chromosome Xq23 Is Associated With Lower Atherogenic Lipid Concentrations And Favorable Cardiometabolic Indices, Pradeep Natarajan, Lucinda Antonacci-Fulton, Susan K. Dutcher, D.C. Rao, C. Charles Gu, Karen Schwander, Yun Ju Sung, Et Al.
Open Access Publications
No abstract provided.
Pushing The Needle Of Entrepreneurship And Innovation: Where Do Plastic And Reconstructive Surgeons Stand?, Sumun Khetpal, Alvaro Reátegui, Joseph Lopez, Justin M. Sacks, Adnan Prsic
Pushing The Needle Of Entrepreneurship And Innovation: Where Do Plastic And Reconstructive Surgeons Stand?, Sumun Khetpal, Alvaro Reátegui, Joseph Lopez, Justin M. Sacks, Adnan Prsic
Open Access Publications
No abstract provided.
Role Of Sirt1 In Isoflurane Conditioning-Induced Neurovascular Protection Against Delayed Cerebral Ischemia Secondary To Subarachnoid Hemorrhage, Meizi Liu, Keshav Jayaraman, Tusar Giri, Gregory J Zipfel, Umeshkumar Athiraman
Role Of Sirt1 In Isoflurane Conditioning-Induced Neurovascular Protection Against Delayed Cerebral Ischemia Secondary To Subarachnoid Hemorrhage, Meizi Liu, Keshav Jayaraman, Tusar Giri, Gregory J Zipfel, Umeshkumar Athiraman
Open Access Publications
We recently reported that isoflurane conditioning provided multifaceted protection against subarachnoid hemorrhage (SAH)-induced delayed cerebral ischemia (DCI), and this protection was through the upregulation of endothelial nitric oxide synthase (eNOS). SIRT1, an NAD-dependent deacetylase, was shown to be one of the critical regulators of eNOS. The aim of our current study is to examine the role of SIRT1 in isoflurane conditioning-induced neurovascular protection against SAH-induced DCI. Mice were divided into four groups: sham, SAH, or SAH with isoflurane conditioning (with and without EX-527). Experimental SAH via endovascular perforation was performed. Anesthetic conditioning was performed with isoflurane 2% for 1 h, …