Digital Commons Network^™

Bves And Ndrg4 Regulate Directional Epicardial Cell Migration Through Autocrine Extracellular Matrix Deposition, Emily C. Benesh, Paul M. Miller, Elise R. Pfaltzgraff, Nathan E. Grega-Larson, Hillary A. Hager, Bong Hwan Sung, Xianghu Qu, H. Scott Baldwin, Alissa M. Weaver, David M. Bader

Open Access Publications

No abstract provided.

Evidence For Transgenerational Metabolic Programming In Drosophila, Jessica L. Buescher, Laura P. Musselman, Christina A. Wilson, Tieming Lang, Madeline Keleher, Thomas J. Baranski, Jennifer G. Duncan

Open Access Publications

No abstract provided.

Molecular Characterization Of Articular Cartilage From Young Adults With Femoroacetabular Impingement, Shingo Hashimoto, Muhammad Farooq Rai, Corey S. Gill, Zhiqi Zhang, Linda J. Sandell, John C. Clohisy

Open Access Publications

No abstract provided.

Mapping Functional Transcription Factor Networks From Gene Expression Data, Brian C. Haynes, Ezekiel J. Maier, Michael H. Kramer, Patricia I. Wang, Holly Brown, Michael R. Brent

Open Access Publications

No abstract provided.

Relationships Among Hiv Infection, Metabolic Risk Factors, And Left Ventricular Structure And Function, William Todd Cade, Edgar Turner Overton, Kristin Mondy, Lisa De Las Fuentes, Victor G. Davila-Roman, Alan D. Waggoner, Dominic N. Reeds, Sherry Lassa-Claxton, Melissa J. Krauss, Linda R. Peterson, Keven E. Yarasheski

Open Access Publications

No abstract provided.

Interscalene Brachial Plexus Block For Arthroscopic Shoulder Surgery: A Systematic Review, Michael S. Hughes, Matthew J. Matava, Rick W. Wright, Robert H. Brophy, Matthew V. Smith

Open Access Publications

No abstract provided.

What's New In Orthopaedic Trauma, William M. Ricci, Andre Spiguel, Christopher Mcandrew, Michael Gardner

Open Access Publications

No abstract provided.

Progression Of Foot Deformity In Charcot Neuropathic Osteoarthropathy, Mary K. Hastings, Jeffrey E. Johnson, Michael J. Strube, Charles F. Hildebolt, Kathryn L. Bohnert, Fred W. Prior, David R. Sinacore

Open Access Publications

No abstract provided.

What's New In Spine Surgery, Keith H. Bridwell, Paul A. Anderson, Scott D. Boden, Alexander R. Vaccaro, Jeffrey C. Wang

Open Access Publications

No abstract provided.

Differential Lymph Node Retrieval In Rectal Cancer: Associated Factors And Effect On Survival, Cedrek Mcfadden, Brian Mckinley, Brian Greenwell, Kaylee Knuckolls, Patrick Culumovic, David Schammel, Christine Schammel, Steven D. Trocha

Open Access Publications

BACKGROUND: Recent publications have identified positive associations between numbers of lymph nodes pathologically examined and five-year overall survival (5-yr OS) in colon cancer. However, focused examinations of relationships between survival of rectal cancer and lymph node counts are less common. We conducted a single institution, retrospective review of rectal cancer resections to determine whether lymph node counts correlated with 5-yr OS and to explore the relationship between lymph node counts and various clinical and pathologic factors.

METHODS: A retrospective review of our institutional tumor registry identified 159 patients with AJCC Stage 1, 2, or 3 rectal cancers that underwent surgical …

Global Analysis Of Drosophila Cys2-His2 Zinc Finger Proteins Reveals A Multitude Of Novel Recognition Motifs And Binding Determinants, Ryan G. Christensen, Gary D. Stormo, Et Al

Open Access Publications

No abstract provided.

Obesity Is Associated With Poor Surgical Outcome In Crohn's Disease, Talha Malik, Ashish Manne, Robert Oster, Austin Eckhoff, Seidu Inusah, Alexandra M Gutierrez

Open Access Publications

BACKGROUND: Published data suggest a link between obesity and adverse outcomes in Crohn's disease (CD). We aimed to test the hypothesis that obese CD patients would be more likely than non-obese CD patients to have poor surgical outcome when undergoing surgery for a complication of CD.

METHODS: We designed a retrospective cohort study to test our hypothesis. The population comprised of adult CD patients who underwent CD related surgery at a tertiary referral center. The exposed and unexposed cohorts were represented by patients who were obese vs. non-obese at the pre-op visit respectively. Outcome was represented by successful vs. unsuccessful …

Ulnar Collateral Ligament Injuries Of The Thumb: Phalangeal Translation During Valgus Stress In Human Cadavera, Kathleen E. Mckeon, Richard H. Gelberman, Ryan P. Calfee

Open Access Publications

No abstract provided.

Protective Effect Of Surfactant Protein D In Pulmonary Vaccinia Virus Infection: Implication Of A27 Viral Protein, Julien Perino, Nicole M. Thielens, Erika Crouch, Danièle Spehner, Jean-Marc Crance, Anne-Laure Favier

Open Access Publications

No abstract provided.

Somatic Neurofibromatosis Type 1 (Nf1) Inactivation Characterizes Nf1-Associated Pilocytic Astrocytoma, David H. Gutmann, Michael D. Mclellan, Ibrahim Hussain, John W. Wallis, Lucinda L. Fulton, Robert S. Fulton, Vincent Magrini, Ryan Demeter, Todd Wylie, Cyriac Kandoth, Jeffrey R. Leonard, Abhijit Guha, Christopher A. Miller, Li Ding, Elaine R. Mardis

Open Access Publications

No abstract provided.

Evolutionarily Novel Functional Networks In The Human Brain?, Dante Mantini, Maurizio Corbetta, Gian Luca Romani, Guy A. Orban, Wim Vanduffel

Open Access Publications

Primate evolution has been accompanied by complex reorganizations in brain anatomy and function. Little is known, however, about the relationship between anatomical and functional changes induced through primate evolution. Using functional magnetic resonance imaging, we assessed spatial and temporal correspondences of cortical networks in humans and monkeys. We provided evidence for topologically and functionally correspondent networks in sensory-motor and attention regions. More specifically, we revealed a possible monkey equivalent of the human ventral attention network. For other human networks, such as the language and the default-mode networks, we detected topological correspondent networks in the monkey, but with different functional signatures. …

Fatty Acid Transport Protein 4 (Fatp4) Prevents Light-Induced Degeneration Of Cone And Rod Photoreceptors By Inhibiting Rpe65 Isomerase, Songhua Li, Jungsoo Lee, Yongdong Zhou, William C. Gordon, James M. Hill, Nicolas G. Bazan, Jeffrey H. Miner, Minghao Jin

Open Access Publications

Although rhodopsin is essential for sensing light for vision, it also mediates light-induced apoptosis of photoreceptors in mouse. RPE65, which catalyzes isomerization of all-trans retinyl fatty acid esters to 11-cis-retinol (11cROL) in the visual cycle, controls the rhodopsin regeneration rate and photoreceptor susceptibility to light-induced degeneration. Mutations in RPE65 have been linked to blindness in affected children. Despite such importance, the mechanism that regulates RPE65 function remains unclear. Through unbiased expression screening of a bovine retinal pigment epithelium (RPE) cDNA library, we have identified elongation of very long-chain fatty acids-like 1 (ELOVL1) and fatty acid transport protein 4 (FATP4), which …

The Disruption Of Celf6, A Gene Identified By Translational Profiling Of Serotonergic Neurons, Results In Autism-Related Behaviors, Joseph D. Dougherty, Susan E. Maloney, David F. Wozniak, Michael A. Rieger, Lisa Sonnenblick, Giovanni Coppola, Nathaniel G. Mahieu, Juliet Zhang, Jinlu Cai, Gary J. Patti, Brett S. Abrahams, Daniel H. Geschwind, Nathaniel Heintz

Open Access Publications

The immense molecular diversity of neurons challenges our ability to understand the genetic and cellular etiology of neuropsychiatric disorders. Leveraging knowledge from neurobiology may help parse the genetic complexity: identifying genes important for a circuit that mediates a particular symptom of a disease may help identify polymorphisms that contribute to risk for the disease as a whole. The serotonergic system has long been suspected in disorders that have symptoms of repetitive behaviors and resistance to change, including autism. We generated a bacTRAP mouse line to permit translational profiling of serotonergic neurons. From this, we identified several thousand serotonergic-cell expressed transcripts, …

Management Of Chronic Pain In Elderly Frail Patients Finding A Suitable Personalized Method Of Control, Rahul Rastogi, Brian D. Meek

Open Access Publications

No abstract provided.

Identification Of A Pan-Cancer Oncogenic Microrna Superfamily Anchored By A Central Core Seed Motif, Mark P. Hamilton, Kimal Rajapakshe, Sean M. Hartig, Boris Reva, Michael D. Mclellan, Cyriac Kandoth, Li Ding, Travis I. Zack, Preethi H. Gunaratne, David A. Wheeler, Cristian Coarfa, Sean E. Mcguire

Open Access Publications

No abstract provided.

Rapid-Selex For Rna Aptamers, Kylan Szeto, David R. Latulippe, Abdullah Ozer, John M. Pagano, Brian S. White, David Shalloway, John T. Lis, Harold G. Craighead

Open Access Publications

No abstract provided.

Adaptive Evolution Of The Streptococcus Pyogenes Regulatory Aldolase Lacd.1, Zachary Cusumano, Michael Caparon

Open Access Publications

No abstract provided.

Clostridium Difficile Ribotype Diversity At Six Health Care Institutions In The United States, Sheila Waslawski, Eugene S. Lo, Sarah A. Ewing, Vincent B. Young, David M. Aronoff, Susan E. Sharp, Susan M. Novak-Weekley, Arthur E. Crist Jr, W. Michael Dunne, Joan Hoppe-Bauer, Michelle Johnson, Stephen M. Brecher, Duane W. Newton, Seth T. Walk

Open Access Publications

No abstract provided.

Role Of Trem1-Dap12 In Renal Inflammation During Obstructive Nephropathy, Alessandra Tammaro, Ingrid Stroo, Elena Rampanelli, Froilan Blank, Loes M. Butter, Nike Claessen, Toshiyuki Takai, Marco Colonna, Jaklien C. Leemans, Sandrine Florquin, Mark C. Dessing

Open Access Publications

No abstract provided.

Functional Intersection Of Atm And Dna-Dependent Protein Kinase Catalytic Subunit In Coding End Joining During V(D)J Recombination, Baeck-Seung Lee, Eric J. Gapud, Yair Dorsett, Andrea Bredemeyer, Rosmy George, Oleg Osipovich, Eugene M. Oltz, Barry P. Sleckman, Et Al

Open Access Publications

No abstract provided.

Acute Ebv Infection Masquerading As "In-Situ Follicular Lymphoma": A Pitfall In The Differential Diagnosis Of This Entity, Alejandro A. Gru, Friederike Kreisel, Eric Duncavage, Tudung T. Nguyen, Anjum Hassan, John L. Frater

Open Access Publications

No abstract provided.

Observer Ratings Of Neighborhoods: Comparison Of Two Methods, Elena M. Andresen, Theodore K. Malmstrom, Mario Schootman, Fredric D. Wolinsky, J. Philip Miller, Douglas K. Miller

Open Access Publications

No abstract provided.

An Emerging Place For Lung Cancer Genomics In 2013, Marissa G. Daniels, Rayleen V. Bowman, Ian A. Yang, Ramaswamy Govindan, Kwun M. Fong

Open Access Publications

No abstract provided.

A Phase 2 Trial Of Ponatinib In Philadelphia Chromosome-Positive Leukemias, J. Dipersio, Et Al

Open Access Publications

No abstract provided.

Prolonged Systemic Inflammation Persistently Modifies Synaptic Plasticity In The Hippocampus: Modulation By The Stress Hormones, Nicola Maggio, Efrat Shavit-Stein, Amir Dori, Ilan Blatt, Joab Chapman

Open Access Publications

No abstract provided.