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Structure Of Cellular Escrt-Iii Spirals And Their Relationship To Hiv Budding, Anil G. Cashikar, Soomin Shim, Robyn Roth, Michael R. Maldazys, John E. Heuser, Phyllis I. Hanson Jan 2014

Structure Of Cellular Escrt-Iii Spirals And Their Relationship To Hiv Budding, Anil G. Cashikar, Soomin Shim, Robyn Roth, Michael R. Maldazys, John E. Heuser, Phyllis I. Hanson

Open Access Publications

No abstract provided.


Invariance And Plasticity In The Drosophila Melanogaster Metabolomic Network In Response To Temperature, Ramkumar Hariharan, Jessica M. Hoffman, Ariel S. Thomas, Quinlyn A. Soltow, Dean P. Jones, Daniel E.L. Promislow Jan 2014

Invariance And Plasticity In The Drosophila Melanogaster Metabolomic Network In Response To Temperature, Ramkumar Hariharan, Jessica M. Hoffman, Ariel S. Thomas, Quinlyn A. Soltow, Dean P. Jones, Daniel E.L. Promislow

Open Access Publications

No abstract provided.


Missed Opportunities: Racial And Neighborhood Socioeconomic Disparities In Emergency Colorectal Cancer Diagnosis And Surgery, Sandi L. Pruitt, Nicholas O. Davidson, Samir Gupta, Yan Yan, Mario Schootman Jan 2014

Missed Opportunities: Racial And Neighborhood Socioeconomic Disparities In Emergency Colorectal Cancer Diagnosis And Surgery, Sandi L. Pruitt, Nicholas O. Davidson, Samir Gupta, Yan Yan, Mario Schootman

Open Access Publications

No abstract provided.


Short Communication: The Veterans Aging Cohort Study Index Is An Effective Tool To Assess Baseline Frailty Status In A Contemporary Cohort Of Hiv-Infected Persons, Gerome V. Escota, Pragna Patel, John T. Brooks, Tim Bush, Lois Conley, Jason Baker, Erna M. Kojic, John Hammer, Nur F. Önen Jan 2014

Short Communication: The Veterans Aging Cohort Study Index Is An Effective Tool To Assess Baseline Frailty Status In A Contemporary Cohort Of Hiv-Infected Persons, Gerome V. Escota, Pragna Patel, John T. Brooks, Tim Bush, Lois Conley, Jason Baker, Erna M. Kojic, John Hammer, Nur F. Önen

Open Access Publications

No abstract provided.


Dynamometer-Based Measure Of Spasticity Confirms Limited Association Between Plantarflexor Spasticity And Walking Function In Persons With Multiple Sclerosis, Theodore R. Kremer, Linda R. Van Dillen, Joanne M. Wagner Jan 2014

Dynamometer-Based Measure Of Spasticity Confirms Limited Association Between Plantarflexor Spasticity And Walking Function In Persons With Multiple Sclerosis, Theodore R. Kremer, Linda R. Van Dillen, Joanne M. Wagner

Open Access Publications

No abstract provided.


Adrenal Myelolipoma: Operative Indications And Outcomes, Victoria M. Gershuni, James G. Bittner Iv, Jeffrey F. Moley, L. Michael Brunt Dec 2013

Adrenal Myelolipoma: Operative Indications And Outcomes, Victoria M. Gershuni, James G. Bittner Iv, Jeffrey F. Moley, L. Michael Brunt

Open Access Publications

No abstract provided.


Renal Cryoablation Versus Robot-Assisted Partial Nephrectomy: Washington University Long-Term Experience, Youssef S. Tanagho, Sam B. Bhayani, Eric H. Kim, R. Sherburne Figenshau Dec 2013

Renal Cryoablation Versus Robot-Assisted Partial Nephrectomy: Washington University Long-Term Experience, Youssef S. Tanagho, Sam B. Bhayani, Eric H. Kim, R. Sherburne Figenshau

Open Access Publications

No abstract provided.


Neuronal Clearance Of Amyloid-Β By Endocytic Receptor Lrp1, Takahisa Kanekiyo, John R. Cirrito, Chia-Chen Liu, Mitsuru Shinohara, Jie Li, Dorothy R. Schuler, Motoko Shinohara, David M. Holtzman, Guojun Bu Dec 2013

Neuronal Clearance Of Amyloid-Β By Endocytic Receptor Lrp1, Takahisa Kanekiyo, John R. Cirrito, Chia-Chen Liu, Mitsuru Shinohara, Jie Li, Dorothy R. Schuler, Motoko Shinohara, David M. Holtzman, Guojun Bu

Open Access Publications

Alzheimer's disease (AD) is the most prevalent form of dementia in the elderly population. Accumulation, aggregation, and deposition of amyloid-β (Aβ) peptides generated through proteolytic cleavage of amyloid precursor protein (APP) are likely initiating events in the pathogenesis of AD. While Aβ production is accelerated in familial AD, increasing evidence indicates that impaired clearance of Aβ is responsible for late-onset AD. Because Aβ is mainly generated in neurons, these cells are predicted to have the highest risk of encountering Aβ among all cell types in the brain. However, it is still unclear whether they are also involved in Aβ clearance. …


The Fc Region Of An Antibody Impacts The Neutralization Of West Nile Viruses In Different Maturation States, Phong D. Lee, Swati Mukherjee, Melissa A. Edeling, Kimberly A. Dowd, S. Kyle Austin, Carolyn J. Manhart, Michael S. Diamond, Daved H. Fremont, Theodore C. Pierson Dec 2013

The Fc Region Of An Antibody Impacts The Neutralization Of West Nile Viruses In Different Maturation States, Phong D. Lee, Swati Mukherjee, Melissa A. Edeling, Kimberly A. Dowd, S. Kyle Austin, Carolyn J. Manhart, Michael S. Diamond, Daved H. Fremont, Theodore C. Pierson

Open Access Publications

No abstract provided.


Chronic Joint Disease Caused By Persistent Chikungunya Virus Infection Is Controlled By The Adaptive Immune Response, David W. Hawman, Kristina A. Stoermer, Stephanie A. Montgomery, Pankaj Pal, Lauren Oko, Michael S. Diamond, Thomas E. Morrison Dec 2013

Chronic Joint Disease Caused By Persistent Chikungunya Virus Infection Is Controlled By The Adaptive Immune Response, David W. Hawman, Kristina A. Stoermer, Stephanie A. Montgomery, Pankaj Pal, Lauren Oko, Michael S. Diamond, Thomas E. Morrison

Open Access Publications

No abstract provided.


Dietary Protein Restriction Inhibits Tumor Growth In Human Xenograft Models Of Prostate And Breast Cancer, Luigi Fontana, Remi M. Adelaiye, Antonella L. Rastelli, Kiersten Marie Miles, Eric Ciamporcero, Valter D. Longo, Holly Nguyen, Robert Vessella, Roberto Pili Dec 2013

Dietary Protein Restriction Inhibits Tumor Growth In Human Xenograft Models Of Prostate And Breast Cancer, Luigi Fontana, Remi M. Adelaiye, Antonella L. Rastelli, Kiersten Marie Miles, Eric Ciamporcero, Valter D. Longo, Holly Nguyen, Robert Vessella, Roberto Pili

Open Access Publications

No abstract provided.


Loss Of The Spectraplakin Short Stop Activates The Dlk Injury Response Pathway In Drosophila, Vera Valakh, Lauren J. Walker, James B. Skeath, Aaron Diantonio Nov 2013

Loss Of The Spectraplakin Short Stop Activates The Dlk Injury Response Pathway In Drosophila, Vera Valakh, Lauren J. Walker, James B. Skeath, Aaron Diantonio

Open Access Publications

No abstract provided.


The Choroid Plexus And Cerebrospinal Fluid: Emerging Roles In Development, Disease, And Therapy, Maria K. Lehtinen, Christopher S. Bjornsson, Susan M. Dymecki, Richard J. Gilbertson, David M. Holtzman, Edwin S. Monuki Nov 2013

The Choroid Plexus And Cerebrospinal Fluid: Emerging Roles In Development, Disease, And Therapy, Maria K. Lehtinen, Christopher S. Bjornsson, Susan M. Dymecki, Richard J. Gilbertson, David M. Holtzman, Edwin S. Monuki

Open Access Publications

No abstract provided.


Wormbase 2014: New Views Of Curated Biology, Tamberlyn Bieri, Philip Ozersky, Tim Schedl, John Spieth, Et Al Nov 2013

Wormbase 2014: New Views Of Curated Biology, Tamberlyn Bieri, Philip Ozersky, Tim Schedl, John Spieth, Et Al

Open Access Publications

No abstract provided.


Gpr126 Functions In Schwann Cells To Control Differentiation And Myelination Via G-Protein Activation, Amit Mogha, Andrew E. Benesh, Chinmoy Patra, Felix B. Engel, Torsten Schoneberg, Ines Liebscher, Kelly R. Monk Nov 2013

Gpr126 Functions In Schwann Cells To Control Differentiation And Myelination Via G-Protein Activation, Amit Mogha, Andrew E. Benesh, Chinmoy Patra, Felix B. Engel, Torsten Schoneberg, Ines Liebscher, Kelly R. Monk

Open Access Publications

No abstract provided.


Cd47 Plays A Critical Role In T-Cell Recruitment By Regulation Of Lfa-1 And Vla-4 Integrin Adhesive Functions, Veronica Azcutia, Matthew Routledge, Marcie R. Williams, Gail Newton, William A. Frazier, Andre Manica, Kevin J. Croce, Charles A. Parkos, Angela B. Schmider, Melissa V. Turman, Roy J. Soberman, Francis W. Luscinskas Nov 2013

Cd47 Plays A Critical Role In T-Cell Recruitment By Regulation Of Lfa-1 And Vla-4 Integrin Adhesive Functions, Veronica Azcutia, Matthew Routledge, Marcie R. Williams, Gail Newton, William A. Frazier, Andre Manica, Kevin J. Croce, Charles A. Parkos, Angela B. Schmider, Melissa V. Turman, Roy J. Soberman, Francis W. Luscinskas

Open Access Publications

No abstract provided.


A Novel Hap1-Tsc1 Interaction Regulates Neuronal Mtorc1 Signaling And Morphogenesis In The Brain, Luis A. Mejia, Nadia Litterman, Yoshiho Ikeuchi, Luis De La Torre-Ubieta, Eric J. Bennett, Chi Zhang, J. Wade Harper, Azad Bonni Nov 2013

A Novel Hap1-Tsc1 Interaction Regulates Neuronal Mtorc1 Signaling And Morphogenesis In The Brain, Luis A. Mejia, Nadia Litterman, Yoshiho Ikeuchi, Luis De La Torre-Ubieta, Eric J. Bennett, Chi Zhang, J. Wade Harper, Azad Bonni

Open Access Publications

No abstract provided.


Global Expression Analysis Of The Yeast Lachancea (Saccharomyces) Kluyveri Reveals New Urc Genes Involved In Pyrimidine Catabolism, Anna Andersson Rasmussen, Dineshkumar Kandasamy, Halfdan Beck, Seth D. Crosby, Olof Bjornberg, Klaus D. Schnackerz, Jure Piskur Nov 2013

Global Expression Analysis Of The Yeast Lachancea (Saccharomyces) Kluyveri Reveals New Urc Genes Involved In Pyrimidine Catabolism, Anna Andersson Rasmussen, Dineshkumar Kandasamy, Halfdan Beck, Seth D. Crosby, Olof Bjornberg, Klaus D. Schnackerz, Jure Piskur

Open Access Publications

No abstract provided.


Distinct Balance Of Excitation And Inhibition In An Interareal Feedforward And Feedback Circuit Of Mouse Visual Cortex, Weiguo Yang, Yarimar Carrasquillo, Bryan M. Hooks, Jeanne M. Nerbonne, Andreas Burkhalter Oct 2013

Distinct Balance Of Excitation And Inhibition In An Interareal Feedforward And Feedback Circuit Of Mouse Visual Cortex, Weiguo Yang, Yarimar Carrasquillo, Bryan M. Hooks, Jeanne M. Nerbonne, Andreas Burkhalter

Open Access Publications

No abstract provided.


The Major Brain Cholesterol Metabolite 24(S)-Hydroxycholesterol Is A Potent Allosteric Modulator Of N-Methyl-D-Aspartate Receptors, Steven M. Paul, James J. Doherty, Albert J. Robichaud, Gabriel M. Belfort, Brian Y. Chow, Rebecca S. Hammond, Devon C. Crawford, Andrew J. Linsenbardt, Hong-Jin Shu, Yukitoshi Izumi, Steven J. Mennerick, Charles F. Zorumski Oct 2013

The Major Brain Cholesterol Metabolite 24(S)-Hydroxycholesterol Is A Potent Allosteric Modulator Of N-Methyl-D-Aspartate Receptors, Steven M. Paul, James J. Doherty, Albert J. Robichaud, Gabriel M. Belfort, Brian Y. Chow, Rebecca S. Hammond, Devon C. Crawford, Andrew J. Linsenbardt, Hong-Jin Shu, Yukitoshi Izumi, Steven J. Mennerick, Charles F. Zorumski

Open Access Publications

No abstract provided.


Dopamine-Dependent Compensation Maintains Motor Behavior In Mice With Developmental Ablation Of Dopaminergic Neurons, Judith P. Golden, Joseph A. Demaro Iii, Amanda Knoten, Masato Hoshi, Elizabeth Pehek, Eugene M. Johnson Jr, Robert W. Gereau Iv, Sanjay Jain Oct 2013

Dopamine-Dependent Compensation Maintains Motor Behavior In Mice With Developmental Ablation Of Dopaminergic Neurons, Judith P. Golden, Joseph A. Demaro Iii, Amanda Knoten, Masato Hoshi, Elizabeth Pehek, Eugene M. Johnson Jr, Robert W. Gereau Iv, Sanjay Jain

Open Access Publications

No abstract provided.


Pathogenic Cd4+ T Cells Recognizing An Unstable Peptide Of Insulin Are Directly Recruited Into Islets Bypassing Local Lymph Nodes, James F. Mohan, Boris Calderon, Mark S. Anderson, Emil R. Unanue Oct 2013

Pathogenic Cd4+ T Cells Recognizing An Unstable Peptide Of Insulin Are Directly Recruited Into Islets Bypassing Local Lymph Nodes, James F. Mohan, Boris Calderon, Mark S. Anderson, Emil R. Unanue

Open Access Publications

No abstract provided.


Nanoscale Protein Architecture Of The Kidney Glomerular Basement Membrane, Hani Suleiman, Lei Zhang, Robyn Roth, John E. Heuser, Jeffrey H. Miner, Andrey S. Shaw, Adish Dani Oct 2013

Nanoscale Protein Architecture Of The Kidney Glomerular Basement Membrane, Hani Suleiman, Lei Zhang, Robyn Roth, John E. Heuser, Jeffrey H. Miner, Andrey S. Shaw, Adish Dani

Open Access Publications

No abstract provided.


Murine Cytomegalovirus Protein Pm92 Is A Conserved Regulator Of Viral Late Gene Expression, Travis J. Chapa, Yi-Cheih Perng, Anthony R. French, Dong Yu Oct 2013

Murine Cytomegalovirus Protein Pm92 Is A Conserved Regulator Of Viral Late Gene Expression, Travis J. Chapa, Yi-Cheih Perng, Anthony R. French, Dong Yu

Open Access Publications

No abstract provided.


Isolation And Characterization Of The Herpes Simplex Virus 1 Terminase Complex, Jason D. Heming, Jamie B. Huffman, Lisa M. Jones, Fred L. Homa Oct 2013

Isolation And Characterization Of The Herpes Simplex Virus 1 Terminase Complex, Jason D. Heming, Jamie B. Huffman, Lisa M. Jones, Fred L. Homa

Open Access Publications

No abstract provided.


Meta-Analyses Of Studies Of The Human Microbiota, Catherine A. Lozupone, Jesse Stombaugh, Antonio Gonzalez, Gail Ackermann, Doug Wendel, Yoshiki Vázquez-Baeza, Janet K. Jansson, Jeffrey I. Gordon Oct 2013

Meta-Analyses Of Studies Of The Human Microbiota, Catherine A. Lozupone, Jesse Stombaugh, Antonio Gonzalez, Gail Ackermann, Doug Wendel, Yoshiki Vázquez-Baeza, Janet K. Jansson, Jeffrey I. Gordon

Open Access Publications

No abstract provided.


Blackops: Increasing Confidence In Variant Detection Through Mappability Filtering, Christopher R. Cabanski, Matthew D. Wilkerson, Matthew Soloway, Joel S. Parker, Jinze Liu, Jan F. Prins, J S. Marron, Charles M. Perou, D Neil Hayes Oct 2013

Blackops: Increasing Confidence In Variant Detection Through Mappability Filtering, Christopher R. Cabanski, Matthew D. Wilkerson, Matthew Soloway, Joel S. Parker, Jinze Liu, Jan F. Prins, J S. Marron, Charles M. Perou, D Neil Hayes

Open Access Publications

No abstract provided.


Latent Gammaherpesvirus 68 Infection Induces Distinct Transcriptional Changes In Different Organs, Susan P. Canny, Gautam Goel, Tiffany A. Reese, Xin Zhang, Ramnik Xavier, Herbert W. Virgin Oct 2013

Latent Gammaherpesvirus 68 Infection Induces Distinct Transcriptional Changes In Different Organs, Susan P. Canny, Gautam Goel, Tiffany A. Reese, Xin Zhang, Ramnik Xavier, Herbert W. Virgin

Open Access Publications

No abstract provided.


Continuous Cyclic Mechanical Tension Increases Ank Expression In Endplate Chondrocytes Through The Tgf-Β1 And P38 Pathway, H Xu, X Zhang, H Wang, Y Zhang, Y Shi, X Zhang Sep 2013

Continuous Cyclic Mechanical Tension Increases Ank Expression In Endplate Chondrocytes Through The Tgf-Β1 And P38 Pathway, H Xu, X Zhang, H Wang, Y Zhang, Y Shi, X Zhang

Open Access Publications

The normal ANK protein has a strong influence on anti-calcification. It is known that TGF-β1 is also able to induce extracellular inorganic pyrophosphate (ePPi) elaboration via the TGF-β1-induced ank gene expression and the mitogen-activated protein kinase (MAPK) signaling acts as a downstream effector of TGF-β1. We hypothesized that the expression of the ank gene is regulated by mechanics through TGF-β1-p38 pathway. In this study, we investigated the mechanism of short-time mechanical tension-induced ank gene expression. We found that the continuous cyclic mechanical tension (CCMT) increased the ank gene expression in the endplate chondrocytes, and there was an increase in the …


Policies On Worksite Lactation Support Within States And Organizations, Safina Abdulloeva, Amy A. Eyler Sep 2013

Policies On Worksite Lactation Support Within States And Organizations, Safina Abdulloeva, Amy A. Eyler

Open Access Publications

No abstract provided.