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High-Throughput Functional Testing Of Encode Segmentation Predictions, Jamie C. Kwasnieski, Christopher Fiore, Hemangi G. Chaudhari, Barak A. Cohen Jan 2014

High-Throughput Functional Testing Of Encode Segmentation Predictions, Jamie C. Kwasnieski, Christopher Fiore, Hemangi G. Chaudhari, Barak A. Cohen

Open Access Publications

No abstract provided.


Clinical Presentation And Disease Characteristics Of Femoroacetabular Impingement Are Sex-Dependent, Jeffrey J. Nepple, Cassandra N. Riggs, James R. Ross, John C. Clohisy Jan 2014

Clinical Presentation And Disease Characteristics Of Femoroacetabular Impingement Are Sex-Dependent, Jeffrey J. Nepple, Cassandra N. Riggs, James R. Ross, John C. Clohisy

Open Access Publications

No abstract provided.


Allele-Specific Network Reveals Combinatorial Interaction That Transcends Small Effects In Psoriasis Gwas, Sharlee Climer, Alan R. Templeton, Weixiong Zhang Jan 2014

Allele-Specific Network Reveals Combinatorial Interaction That Transcends Small Effects In Psoriasis Gwas, Sharlee Climer, Alan R. Templeton, Weixiong Zhang

Open Access Publications

No abstract provided.


Ecog High Gamma Activity Reveals Distinct Cortical Representations Of Lyrics Passages, Harmonic And Timbre-Related Changes In A Rock Song, Irene Sturm, Benjamin Blankertz, Cristhian Potes, Gerwin Schalk, Gabriel Curio Jan 2014

Ecog High Gamma Activity Reveals Distinct Cortical Representations Of Lyrics Passages, Harmonic And Timbre-Related Changes In A Rock Song, Irene Sturm, Benjamin Blankertz, Cristhian Potes, Gerwin Schalk, Gabriel Curio

Open Access Publications

No abstract provided.


Functional Status After Blast-Plus-Impact Complex Concussive Traumatic Brain Injury In Evacuated United States Military Personnel, Christine L. Macdonald, Ann M. Johnson, Elliot C. Nelson, Nicole J. Werner, Raymond Fang, Stephen F. Flaherty, David L. Brody Jan 2014

Functional Status After Blast-Plus-Impact Complex Concussive Traumatic Brain Injury In Evacuated United States Military Personnel, Christine L. Macdonald, Ann M. Johnson, Elliot C. Nelson, Nicole J. Werner, Raymond Fang, Stephen F. Flaherty, David L. Brody

Open Access Publications

No abstract provided.


Sex Dependent Risk Factors For Mortality After Myocardial Infarction: Individual Patient Data Meta-Analysis, Robert M. Carney, Kenneth E. Freedland, Et Al Jan 2014

Sex Dependent Risk Factors For Mortality After Myocardial Infarction: Individual Patient Data Meta-Analysis, Robert M. Carney, Kenneth E. Freedland, Et Al

Open Access Publications

No abstract provided.


Variants Near Chrnb3-Chrna6 Are Associated With Dsm-5 Cocaine Use Disorder: Evidence For Pleiotropy, Brooke Sadler, Gabe Haller, Arpana Agrawal, Rob Culverhouse, Kathleen Bucholz, Andy Brooks, Jay Tischfield, Eric O. Johnson, Howard Edenberg, Marc Schuckit, Nancy Saccone, Laura Bierut, Alison Goate Jan 2014

Variants Near Chrnb3-Chrna6 Are Associated With Dsm-5 Cocaine Use Disorder: Evidence For Pleiotropy, Brooke Sadler, Gabe Haller, Arpana Agrawal, Rob Culverhouse, Kathleen Bucholz, Andy Brooks, Jay Tischfield, Eric O. Johnson, Howard Edenberg, Marc Schuckit, Nancy Saccone, Laura Bierut, Alison Goate

Open Access Publications

No abstract provided.


Potential Role Of Orexin And Sleep Modulation In The Pathogenesis Of Alzheimer's Disease, Jee Hoon Roh, Hong Jiang, Mary Beth Finn, Floy R. Stewart, Thomas E. Mahan, John R. Cirrito, Ashish Heda, B. Joy Snider, Mingjie Li, Masashi Yanagisawa, Luis De Lecea, David M. Holtzman Jan 2014

Potential Role Of Orexin And Sleep Modulation In The Pathogenesis Of Alzheimer's Disease, Jee Hoon Roh, Hong Jiang, Mary Beth Finn, Floy R. Stewart, Thomas E. Mahan, John R. Cirrito, Ashish Heda, B. Joy Snider, Mingjie Li, Masashi Yanagisawa, Luis De Lecea, David M. Holtzman

Open Access Publications

Age-related aggregation of amyloid-β (Aβ) is an upstream pathological event in Alzheimer's disease (AD) pathogenesis, and it disrupts the sleep-wake cycle. The amount of sleep declines with aging and to a greater extent in AD. Poor sleep quality and insufficient amounts of sleep have been noted in humans with preclinical evidence of AD. However, how the amount and quality of sleep affects Aβ aggregation is not yet well understood. Orexins (hypocretins) initiate and maintain wakefulness, and loss of orexin-producing neurons causes narcolepsy. We tried to determine whether orexin release or secondary changes in sleep via orexin modulation affect Aβ pathology. …


Tumor-Induced Stat3 Activation In Monocytic Myeloid-Derived Suppressor Cells Enhances Stemness And Mesenchymal Properties In Human Pancreatic Cancer, Roheena Z. Panni, Dominic E. Sanford, Brian A. Belt, Jonathan B. Mitchem, Lori A. Worley, Brian D. Goetz, Pinku Mukherjee, Andrea Wang-Gillam, Daniel C. Link, David G. Denardo, S. Peter Goedegebuure, David C. Linehan Jan 2014

Tumor-Induced Stat3 Activation In Monocytic Myeloid-Derived Suppressor Cells Enhances Stemness And Mesenchymal Properties In Human Pancreatic Cancer, Roheena Z. Panni, Dominic E. Sanford, Brian A. Belt, Jonathan B. Mitchem, Lori A. Worley, Brian D. Goetz, Pinku Mukherjee, Andrea Wang-Gillam, Daniel C. Link, David G. Denardo, S. Peter Goedegebuure, David C. Linehan

Open Access Publications

No abstract provided.


How Local Excitation-Inhibition Ratio Impacts The Whole Brain Dynamics, Gustavo Deco, Adrian Ponce-Alvarez, Patric Hagmann, Gian Luca Romani, Dante Mantini, Maurizio Corbetta Jan 2014

How Local Excitation-Inhibition Ratio Impacts The Whole Brain Dynamics, Gustavo Deco, Adrian Ponce-Alvarez, Patric Hagmann, Gian Luca Romani, Dante Mantini, Maurizio Corbetta

Open Access Publications

No abstract provided.


Key Issues And Opportunities In The Evolving Health-Care Marketplace: Aoa Critical Issues, Kristin Olds Glavin, Daniel B. Murrey, Joel C. Porter, Donald Brunn, Rick W. Wright Jan 2014

Key Issues And Opportunities In The Evolving Health-Care Marketplace: Aoa Critical Issues, Kristin Olds Glavin, Daniel B. Murrey, Joel C. Porter, Donald Brunn, Rick W. Wright

Open Access Publications

No abstract provided.


Morphologic And Molecular Evaluation Of Chlamydia Trachomatis Growth In Human Endocervix Reveals Distinct Growth Patterns, Wandy L. Beatty, Et Al Jan 2014

Morphologic And Molecular Evaluation Of Chlamydia Trachomatis Growth In Human Endocervix Reveals Distinct Growth Patterns, Wandy L. Beatty, Et Al

Open Access Publications

No abstract provided.


Spatial Reorganization Of Putaminal Dopamine D2-Like Receptors In Cranial And Hand Dystonia, Kevin J. Black, Abraham Z. Snyder, Jonathan W. Mink, Veeral N. Tolia, Fredy J. Revilla, Stephen M. Moerlein, Joel S. Perlmutter Jan 2014

Spatial Reorganization Of Putaminal Dopamine D2-Like Receptors In Cranial And Hand Dystonia, Kevin J. Black, Abraham Z. Snyder, Jonathan W. Mink, Veeral N. Tolia, Fredy J. Revilla, Stephen M. Moerlein, Joel S. Perlmutter

Open Access Publications

No abstract provided.


The Changing Immune System In Sepsis: Is Individualized Immuno-Modulatory Therapy The Answer?, Jonathan S. Boomer, Jonathan M. Green, Richard S. Hotchkiss Jan 2014

The Changing Immune System In Sepsis: Is Individualized Immuno-Modulatory Therapy The Answer?, Jonathan S. Boomer, Jonathan M. Green, Richard S. Hotchkiss

Open Access Publications

No abstract provided.


Genetic Predisposition To Increased Blood Cholesterol And Triglyceride Lipid Levels And Risk Of Alzheimer Disease: A Mendelian Randomization Analysis, Alison Goate, Carlos Cruchaga, Petra Nowotny, John C. Morris, Kevin Mayo, Et Al Jan 2014

Genetic Predisposition To Increased Blood Cholesterol And Triglyceride Lipid Levels And Risk Of Alzheimer Disease: A Mendelian Randomization Analysis, Alison Goate, Carlos Cruchaga, Petra Nowotny, John C. Morris, Kevin Mayo, Et Al

Open Access Publications

No abstract provided.


Changes In Medical Errors After Implementation Of A Handoff Program, F. S. Cole, Et Al Jan 2014

Changes In Medical Errors After Implementation Of A Handoff Program, F. S. Cole, Et Al

Open Access Publications

No abstract provided.


Suicide Genes: Monitoring Cells In Patients With A Safety Switch, Linda G. Eissenberg, Michael Rettig, Farrokh Dehdashti, David Piwnica-Worms, John F. Dipersio Jan 2014

Suicide Genes: Monitoring Cells In Patients With A Safety Switch, Linda G. Eissenberg, Michael Rettig, Farrokh Dehdashti, David Piwnica-Worms, John F. Dipersio

Open Access Publications

No abstract provided.


Spread Of Activation And Deactivation In The Brain: Does Age Matter?, Brian A. Gordon, Chun-Yu Tse, Gabriele Gratton, Monica Fabiani Jan 2014

Spread Of Activation And Deactivation In The Brain: Does Age Matter?, Brian A. Gordon, Chun-Yu Tse, Gabriele Gratton, Monica Fabiani

Open Access Publications

No abstract provided.


The Role Of Resting State Networks In Focal Neocortical Seizures, S. Kathleen Bandt, David T. Bundy, Ammar H. Hawasli, Kareem W. Ayoub, Mohit Sharma, Carl D. Hacker, Mrinal Pahwa, Eric C. Leuthardt Jan 2014

The Role Of Resting State Networks In Focal Neocortical Seizures, S. Kathleen Bandt, David T. Bundy, Ammar H. Hawasli, Kareem W. Ayoub, Mohit Sharma, Carl D. Hacker, Mrinal Pahwa, Eric C. Leuthardt

Open Access Publications

No abstract provided.


The Association Of The Vanin-1 N131s Variant With Blood Pressure Is Mediated By Endoplasmic Reticulum-Associated Degradation And Loss Of Function, Ya-Juan Wang, Bamidele O. Tayo, Anupam Bandyopadhyay, Heming Wang, Tao Feng, Nora Franceschini, Hua Tang, Jianmin Gao, Yun Ju Sung, Cogent Bp Consortium, Robert C. Elston, Scott M. Williams, Richard S. Cooper, Ting-Wei Mu, Xiaofeng Zhu Jan 2014

The Association Of The Vanin-1 N131s Variant With Blood Pressure Is Mediated By Endoplasmic Reticulum-Associated Degradation And Loss Of Function, Ya-Juan Wang, Bamidele O. Tayo, Anupam Bandyopadhyay, Heming Wang, Tao Feng, Nora Franceschini, Hua Tang, Jianmin Gao, Yun Ju Sung, Cogent Bp Consortium, Robert C. Elston, Scott M. Williams, Richard S. Cooper, Ting-Wei Mu, Xiaofeng Zhu

Open Access Publications

No abstract provided.


Multi-Drug Resistance, Inappropriate Initial Antibiotic Therapy And Mortality In Gram-Negative Severe Sepsis And Septic Shock: A Retrospective Cohort Study, Marya D. Zilberberg, Andrew F. Shorr, Scott T. Micek, Cristina Vazquez-Guillamet, Marin H. Kollef Jan 2014

Multi-Drug Resistance, Inappropriate Initial Antibiotic Therapy And Mortality In Gram-Negative Severe Sepsis And Septic Shock: A Retrospective Cohort Study, Marya D. Zilberberg, Andrew F. Shorr, Scott T. Micek, Cristina Vazquez-Guillamet, Marin H. Kollef

Open Access Publications

No abstract provided.


Arterial Spin Labeling Versus Bold In Direct Challenge And Drug-Task Interaction Pharmacological Fmri, Stephanie B. Stewart, Jonathan M. Koller, Meghan C. Campbell, Kevin J. Black Jan 2014

Arterial Spin Labeling Versus Bold In Direct Challenge And Drug-Task Interaction Pharmacological Fmri, Stephanie B. Stewart, Jonathan M. Koller, Meghan C. Campbell, Kevin J. Black

Open Access Publications

No abstract provided.


Extensive Error In The Number Of Genes Inferred From Draft Genome Assemblies, James F. Denton, Jose Lugo-Martinez, Abraham E. Tucker, Daniel R. Schrider, Wesley C. Warren, Matthew W. Hahn Jan 2014

Extensive Error In The Number Of Genes Inferred From Draft Genome Assemblies, James F. Denton, Jose Lugo-Martinez, Abraham E. Tucker, Daniel R. Schrider, Wesley C. Warren, Matthew W. Hahn

Open Access Publications

No abstract provided.


Clonal Architectures And Driver Mutations In Metastatic Melanomas, Li Ding, Minjung Kim, Krishna L. Kanchi, Nathan D. Dees, Charles Lu, Malachi Griffith, David Fenstermacher, Hyeran Sung, Christopher A. Miller, Brian Goetz, Michael C. Wendl, Obi Griffith, Lynn A. Cornelius, Gerald P. Linette, Joshua F. Mcmichael, Vernon K. Sondak, Ryan C. Fields, Timothy J. Ley, James J. Mule, Richard K. Wilson, Jeffrey S. Weber Jan 2014

Clonal Architectures And Driver Mutations In Metastatic Melanomas, Li Ding, Minjung Kim, Krishna L. Kanchi, Nathan D. Dees, Charles Lu, Malachi Griffith, David Fenstermacher, Hyeran Sung, Christopher A. Miller, Brian Goetz, Michael C. Wendl, Obi Griffith, Lynn A. Cornelius, Gerald P. Linette, Joshua F. Mcmichael, Vernon K. Sondak, Ryan C. Fields, Timothy J. Ley, James J. Mule, Richard K. Wilson, Jeffrey S. Weber

Open Access Publications

No abstract provided.


Glycosylation Variants Of A Β-Glucosidase Secreted By A Taiwanese Fungus, Chaetomella Raphigera, Exhibit Variant-Specific Catalytic And Biochemical Properties, Aki Yoneda, Hsion-Wen David Kuo, Mayumi Ishihara, Parastoo Azadi, Su-May Yu, Tuan-Hua David Ho Jan 2014

Glycosylation Variants Of A Β-Glucosidase Secreted By A Taiwanese Fungus, Chaetomella Raphigera, Exhibit Variant-Specific Catalytic And Biochemical Properties, Aki Yoneda, Hsion-Wen David Kuo, Mayumi Ishihara, Parastoo Azadi, Su-May Yu, Tuan-Hua David Ho

Open Access Publications

No abstract provided.


Α2Β1 Integrin, Gpvi Receptor, And Common Fcrγ Chain On Mouse Platelets Mediate Distinct Responses To Collagen In Models Of Thrombosis, Robin J. Marjoram, Zhengzhi Li, Li He, Douglas M. Tollefsen, Thomas J. Kunicki, S. Kent Dickeson, Samuel A. Santoro, Mary M. Zutter Jan 2014

Α2Β1 Integrin, Gpvi Receptor, And Common Fcrγ Chain On Mouse Platelets Mediate Distinct Responses To Collagen In Models Of Thrombosis, Robin J. Marjoram, Zhengzhi Li, Li He, Douglas M. Tollefsen, Thomas J. Kunicki, S. Kent Dickeson, Samuel A. Santoro, Mary M. Zutter

Open Access Publications

No abstract provided.


Antisense Reduction Of The Protein Tau Attenuates Neuronal Hyper-Excitability And Permits Clearance Of Intraneuronal Tau Accumulations In Vivo, Sarah Devos Jan 2014

Antisense Reduction Of The Protein Tau Attenuates Neuronal Hyper-Excitability And Permits Clearance Of Intraneuronal Tau Accumulations In Vivo, Sarah Devos

Open Access Publications

No abstract provided.


Dna Polymerases Ζ And Rev1 Mediate Error-Prone Bypass Of Non-B Dna Structures, Matthew R. Northam, Elizabeth A. Moore, Tony M. Mertz, Sara K. Binz, Carrie M. Stith, Elena I. Stepchenkova, Kathern L. Wendt, Peter M. J. Burgers, Polina V. Scherbakova Jan 2014

Dna Polymerases Ζ And Rev1 Mediate Error-Prone Bypass Of Non-B Dna Structures, Matthew R. Northam, Elizabeth A. Moore, Tony M. Mertz, Sara K. Binz, Carrie M. Stith, Elena I. Stepchenkova, Kathern L. Wendt, Peter M. J. Burgers, Polina V. Scherbakova

Open Access Publications

No abstract provided.


Electronic Health Record: Integrating Evidence-Based Information At The Point Of Clinical Decision Making, Susan A. Fowler, Lauren H. Yaeger, Feliciano Yu, Dwight Doerhoff, Paul Schoening Jan 2014

Electronic Health Record: Integrating Evidence-Based Information At The Point Of Clinical Decision Making, Susan A. Fowler, Lauren H. Yaeger, Feliciano Yu, Dwight Doerhoff, Paul Schoening

Open Access Publications

No abstract provided.


Over-Expression Of Tresk K(+) Channels Reduces The Excitability Of Trigeminal Ganglion Nociceptors, Zhaohua Guo, Yu-Qing Cao Jan 2014

Over-Expression Of Tresk K(+) Channels Reduces The Excitability Of Trigeminal Ganglion Nociceptors, Zhaohua Guo, Yu-Qing Cao

Open Access Publications

No abstract provided.