Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

Articles 1951 - 1980 of 3983

Full-Text Articles in Entire DC Network

An Optimized, Broadly Applicable Piggybac Transposon Induction System, Zongtai Qi, Michael Nathaniel Wilkinson, Xuhua Chen, Sumithra Sankararaman, David Mayhew, Robi David Mitra Jan 2017

An Optimized, Broadly Applicable Piggybac Transposon Induction System, Zongtai Qi, Michael Nathaniel Wilkinson, Xuhua Chen, Sumithra Sankararaman, David Mayhew, Robi David Mitra

Open Access Publications

No abstract provided.


Human Ribonuclease H1 Resolves R-Loops And Thereby Enables Progression Of The Dna Replication Fork, Shankar Parajuli, Daniel C. Teasley, Bhavna Murali, Jessica Jackson, Alessandro Vindigni, Sheila A. Stewart Jan 2017

Human Ribonuclease H1 Resolves R-Loops And Thereby Enables Progression Of The Dna Replication Fork, Shankar Parajuli, Daniel C. Teasley, Bhavna Murali, Jessica Jackson, Alessandro Vindigni, Sheila A. Stewart

Open Access Publications

No abstract provided.


A Method For Quantifying Upper Limb Performance In Daily Life Using Accelerometers, Catherine E. Lang, Kimberly J. Waddell, Joseph W. Klaesner, Marghuretta D. Bland Jan 2017

A Method For Quantifying Upper Limb Performance In Daily Life Using Accelerometers, Catherine E. Lang, Kimberly J. Waddell, Joseph W. Klaesner, Marghuretta D. Bland

Open Access Publications

No abstract provided.


Cerebrospinal Fluid Aβ42/40 Corresponds Better Than Aβ42 To Amyloid Pet In Alzheimer’S Disease, Piotr Lewczuk, Anja Matzen, Kaj Blennow, Lucilla Parnetti, Jose Luis Molinuevo, Paolo Eusebi, Johannes Kornhuber, John C. Morris, Anne M. Fagan Jan 2017

Cerebrospinal Fluid Aβ42/40 Corresponds Better Than Aβ42 To Amyloid Pet In Alzheimer’S Disease, Piotr Lewczuk, Anja Matzen, Kaj Blennow, Lucilla Parnetti, Jose Luis Molinuevo, Paolo Eusebi, Johannes Kornhuber, John C. Morris, Anne M. Fagan

Open Access Publications

No abstract provided.


The Emergence Of Network Inefficiencies In Infants With Autism Spectrum Disorder, John R. Pruett Jr., Kelly N. Botteron, Robert C. Mckinstry, Et Al Jan 2017

The Emergence Of Network Inefficiencies In Infants With Autism Spectrum Disorder, John R. Pruett Jr., Kelly N. Botteron, Robert C. Mckinstry, Et Al

Open Access Publications

No abstract provided.


Recombinant Adeno-Associated Viral Integration And Genotoxicity: Insights From Animal Models, Randy J. Chandler, Mark S. Sands, Charles P. Venditti Jan 2017

Recombinant Adeno-Associated Viral Integration And Genotoxicity: Insights From Animal Models, Randy J. Chandler, Mark S. Sands, Charles P. Venditti

Open Access Publications

No abstract provided.


Aav-Mediated Expression Of Anti-Tau Scfvs Decreases Tau Accumulation In A Mouse Model Of Tauopathy, Christina Ising, Gilbert Gallardo, Cheryl E.G. Leyns, Connie H. Wong, Hong Jiang, Floy Stewart, Lauren J. Koscal, Joseph Roh, Grace O. Robinson, Javier Remolina Serrano, David M. Holtzman Jan 2017

Aav-Mediated Expression Of Anti-Tau Scfvs Decreases Tau Accumulation In A Mouse Model Of Tauopathy, Christina Ising, Gilbert Gallardo, Cheryl E.G. Leyns, Connie H. Wong, Hong Jiang, Floy Stewart, Lauren J. Koscal, Joseph Roh, Grace O. Robinson, Javier Remolina Serrano, David M. Holtzman

Open Access Publications

Tauopathies are characterized by the progressive accumulation of hyperphosphorylated, aggregated forms of tau. Our laboratory has previously demonstrated that passive immunization with an anti-tau antibody, HJ8.5, decreased accumulation of pathological tau in a human P301S tau-expressing transgenic (P301S-tg) mouse model of frontotemporal dementia/tauopathy. To investigate whether the F


Fibroblast Bioenergetics To Classify Amyotrophic Lateral Sclerosis Patients, Csaba Konrad, Hibiki Kawamata, Kirsten G. Bredvik, Andrea J. Arreguin, Steven A. Cajamarca, Jonathan C. Hupf, John M. Ravits, Timothy M. Miller, Nicholas J. Maragakis, Chadwick M. Hales, Jonathan D. Glass, Steven Gross, Hiroshi Mitsumoto, Giovanni Manfredi Jan 2017

Fibroblast Bioenergetics To Classify Amyotrophic Lateral Sclerosis Patients, Csaba Konrad, Hibiki Kawamata, Kirsten G. Bredvik, Andrea J. Arreguin, Steven A. Cajamarca, Jonathan C. Hupf, John M. Ravits, Timothy M. Miller, Nicholas J. Maragakis, Chadwick M. Hales, Jonathan D. Glass, Steven Gross, Hiroshi Mitsumoto, Giovanni Manfredi

Open Access Publications

No abstract provided.


Structured Illumination Diffuse Optical Tomography For Noninvasive Functional Neuroimaging In Mice, Matthew D. Reisman, Zachary E. Markow, Adam Q. Bauer, Joseph P. Culver Jan 2017

Structured Illumination Diffuse Optical Tomography For Noninvasive Functional Neuroimaging In Mice, Matthew D. Reisman, Zachary E. Markow, Adam Q. Bauer, Joseph P. Culver

Open Access Publications

No abstract provided.


Mutant U2af1-Expressing Cells Are Sensitive To Pharmacological Modulation Of The Spliceosome, Cara Lunn Shirai, Brian S. White, Manorama Tripathi, Roberto Tapia, James N. Ley, Matthew Ndonwi, Sanghyun Kim, Jin Shao, Alexa Carver, Borja Saez, Robert S. Fulton, Catrina Fronick, Michelle O’Laughlin, Chandraiah Lagisetti, Thomas R. Webb, Timothy A. Graubert, Matthew J. Walter Jan 2017

Mutant U2af1-Expressing Cells Are Sensitive To Pharmacological Modulation Of The Spliceosome, Cara Lunn Shirai, Brian S. White, Manorama Tripathi, Roberto Tapia, James N. Ley, Matthew Ndonwi, Sanghyun Kim, Jin Shao, Alexa Carver, Borja Saez, Robert S. Fulton, Catrina Fronick, Michelle O’Laughlin, Chandraiah Lagisetti, Thomas R. Webb, Timothy A. Graubert, Matthew J. Walter

Open Access Publications

No abstract provided.


Declines In Prevalence Of Adolescent Substance Use Disorders And Delinquent Behaviors In The Usa: A Unitary Trend?, R. A. Grucza, R. F. Krueger, Arpana Agrawal, A. D. Plunk, M. J. Krauss, J. Bongu, P. A. Cavazos-Rehg, L. J. Bierut Jan 2017

Declines In Prevalence Of Adolescent Substance Use Disorders And Delinquent Behaviors In The Usa: A Unitary Trend?, R. A. Grucza, R. F. Krueger, Arpana Agrawal, A. D. Plunk, M. J. Krauss, J. Bongu, P. A. Cavazos-Rehg, L. J. Bierut

Open Access Publications

No abstract provided.


Familial Screening For Left-Sided Congenital Heart Disease: What Is The Evidence? What Is The Cost?, Daniel J. Perry, Connor R. Mullen, Horacio G. Carvajal, Anoop K. Brar, Pirooz Eghtesady Jan 2017

Familial Screening For Left-Sided Congenital Heart Disease: What Is The Evidence? What Is The Cost?, Daniel J. Perry, Connor R. Mullen, Horacio G. Carvajal, Anoop K. Brar, Pirooz Eghtesady

Open Access Publications

No abstract provided.


Brain Structure In Pediatric Tourette Syndrome, D. J. Greene, A. C. Williams Iii, J. M. Koller, B. L. Schlaggar, K. J. Black, The Tourette Association Of America Neuroimaging Consortium Jan 2017

Brain Structure In Pediatric Tourette Syndrome, D. J. Greene, A. C. Williams Iii, J. M. Koller, B. L. Schlaggar, K. J. Black, The Tourette Association Of America Neuroimaging Consortium

Open Access Publications

No abstract provided.


Dilution Factor Of Quantitative Bacterial Cultures Obtained By Bronchoalveolar Lavage In Patients With Ventilator-Associated Bacterial Pneumonia, Marin H. Kollef, Lisa Mayfield, Ann Doyle, Et Al Jan 2017

Dilution Factor Of Quantitative Bacterial Cultures Obtained By Bronchoalveolar Lavage In Patients With Ventilator-Associated Bacterial Pneumonia, Marin H. Kollef, Lisa Mayfield, Ann Doyle, Et Al

Open Access Publications

No abstract provided.


Preclinical Pet Imaging Of Glycoprotein Non-Metastatic Melanoma B In Triple Negative Breast Cancer: Feasibility Of An Antibody-Based Companion Diagnostic Agent, Bernadette V. Marquez-Nostra, Supum Lee, Richard Laforest, Laura Vitale, Xingyu Nie, Krzysztof Hyrc, Tibor Keler, Thomas Hawthorne, Jeremy Hoog, Shunqiang Li, Farrokh Dehdashti, Cynthia X. Ma, Suzanne E. Lapi Jan 2017

Preclinical Pet Imaging Of Glycoprotein Non-Metastatic Melanoma B In Triple Negative Breast Cancer: Feasibility Of An Antibody-Based Companion Diagnostic Agent, Bernadette V. Marquez-Nostra, Supum Lee, Richard Laforest, Laura Vitale, Xingyu Nie, Krzysztof Hyrc, Tibor Keler, Thomas Hawthorne, Jeremy Hoog, Shunqiang Li, Farrokh Dehdashti, Cynthia X. Ma, Suzanne E. Lapi

Open Access Publications

No abstract provided.


Prediction Of New Stabilizing Mutations Based On Mechanistic Insights From Markov State Models, Maxwell I. Zimmerman, Kathryn M. Hart, Carrie A. Sibbald, Thomas E. Frederick, John R. Jimah, Catherine R. Knoverek, Niraj H. Tolia, Gregory R. Bowman Jan 2017

Prediction Of New Stabilizing Mutations Based On Mechanistic Insights From Markov State Models, Maxwell I. Zimmerman, Kathryn M. Hart, Carrie A. Sibbald, Thomas E. Frederick, John R. Jimah, Catherine R. Knoverek, Niraj H. Tolia, Gregory R. Bowman

Open Access Publications

No abstract provided.


Nuclear Export Factor 3 Regulates Localization Of Small Nucleolar Rnas, Melissa W. Li, Arthur C. Sletten, Jiyeon Lee, Kelly D. Pyles, Scot J. Matkovich, Daniel S. Ory, Jean E. Schaffer Jan 2017

Nuclear Export Factor 3 Regulates Localization Of Small Nucleolar Rnas, Melissa W. Li, Arthur C. Sletten, Jiyeon Lee, Kelly D. Pyles, Scot J. Matkovich, Daniel S. Ory, Jean E. Schaffer

Open Access Publications

No abstract provided.


Use Of A Novel Portable Three-Dimensional Imaging System To Measure Limb Volume And Circumference In Patients With Filarial Lymphedema, Channa Yahathugoda, Michael J. Weiler, Ramakrishna Rao, Lalindi De Silva, J. Brandon Dixon, Mirani V. Weerasooriya, Gary J. Weil, Philip J. Budge Jan 2017

Use Of A Novel Portable Three-Dimensional Imaging System To Measure Limb Volume And Circumference In Patients With Filarial Lymphedema, Channa Yahathugoda, Michael J. Weiler, Ramakrishna Rao, Lalindi De Silva, J. Brandon Dixon, Mirani V. Weerasooriya, Gary J. Weil, Philip J. Budge

Open Access Publications

No abstract provided.


Relationships Between Consumption Of Ultra-Processed Foods, Gestational Weight Gain And Neonatal Outcomes In A Sample Of Us Pregnant Women, Karthik W. Rohatgi, Rachel A. Tinius, W. Todd Cade, Euridice Martinez Steele, Alison G. Cahill, Diana C. Parra Jan 2017

Relationships Between Consumption Of Ultra-Processed Foods, Gestational Weight Gain And Neonatal Outcomes In A Sample Of Us Pregnant Women, Karthik W. Rohatgi, Rachel A. Tinius, W. Todd Cade, Euridice Martinez Steele, Alison G. Cahill, Diana C. Parra

Open Access Publications

No abstract provided.


Linkage, Whole Genome Sequence, And Biological Data Implicate Variants In Rab10 In Alzheimer’S Disease Resilience, Celeste M. Karch, Simon Hsu, Anna R. Damato, Oscar Harari, Victoria M. Fernandez, Carlos Cruchaga, Et Al Jan 2017

Linkage, Whole Genome Sequence, And Biological Data Implicate Variants In Rab10 In Alzheimer’S Disease Resilience, Celeste M. Karch, Simon Hsu, Anna R. Damato, Oscar Harari, Victoria M. Fernandez, Carlos Cruchaga, Et Al

Open Access Publications

No abstract provided.


Assessment Of Healthcare Worker Protocol Deviations And Self-Contamination During Personal Protective Equipment Donning And Doffing, Jennie H. Kwon, Carey-Ann D. Burnham, Kimberly A. Reske, Stephen Y. Liang, Tiffany Hink, Meghan A. Wallace, Angela Shupe, Sondra Seiler, Candice Cass, Victoria J. Fraser, Erik R. Dubberke Jan 2017

Assessment Of Healthcare Worker Protocol Deviations And Self-Contamination During Personal Protective Equipment Donning And Doffing, Jennie H. Kwon, Carey-Ann D. Burnham, Kimberly A. Reske, Stephen Y. Liang, Tiffany Hink, Meghan A. Wallace, Angela Shupe, Sondra Seiler, Candice Cass, Victoria J. Fraser, Erik R. Dubberke

Open Access Publications

No abstract provided.


The Genome And Adult Somatic Transcriptome Of The Mormyrid Electric Fish Paramormyrops Kingsleyae, Jason R. Gallant, Mauricio Losilla, Chad Tomlinson, Wesley C. Warren Jan 2017

The Genome And Adult Somatic Transcriptome Of The Mormyrid Electric Fish Paramormyrops Kingsleyae, Jason R. Gallant, Mauricio Losilla, Chad Tomlinson, Wesley C. Warren

Open Access Publications

No abstract provided.


Contralateral Inhibition Of Click- And Chirp-Evoked Human Compound Action Potentials, Spencer B. Smith, Jeffery T. Lichtenhan, Barbara K. Cone Jan 2017

Contralateral Inhibition Of Click- And Chirp-Evoked Human Compound Action Potentials, Spencer B. Smith, Jeffery T. Lichtenhan, Barbara K. Cone

Open Access Publications

No abstract provided.


Nipple‑Sparing Mastectomies: Clinical Outcomes From A Single Academic Institution, Barbara Dull, Leah Conant, Terence Myckatyn, Marissa Tenenbaum, Amy Cyr, Julie A. Margenthaler Jan 2017

Nipple‑Sparing Mastectomies: Clinical Outcomes From A Single Academic Institution, Barbara Dull, Leah Conant, Terence Myckatyn, Marissa Tenenbaum, Amy Cyr, Julie A. Margenthaler

Open Access Publications

No abstract provided.


Loss Of Navβ4-Mediated Regulation Of Sodium Currents In Adult Purkinje Neurons Disrupts Firing And Impairs Motor Coordination And Balance, Joseph L. Ransdell, Edward Dranoff, Brandon Lau, Wan-Lin Lo, David L. Donermeyer, Paul M. Allen, Jeanne M. Nerbonne Jan 2017

Loss Of Navβ4-Mediated Regulation Of Sodium Currents In Adult Purkinje Neurons Disrupts Firing And Impairs Motor Coordination And Balance, Joseph L. Ransdell, Edward Dranoff, Brandon Lau, Wan-Lin Lo, David L. Donermeyer, Paul M. Allen, Jeanne M. Nerbonne

Open Access Publications

No abstract provided.


Stress-Induced Reinstatement Of Nicotine Preference Requires Dynorphin/Kappa Opioid Activity In The Basolateral Amygdala, Stephanie K. Nygard, Nicholas J. Hourguettes, Gabe G. Sobczak, William A. Carlezon, Michael R. Bruchas Sep 2016

Stress-Induced Reinstatement Of Nicotine Preference Requires Dynorphin/Kappa Opioid Activity In The Basolateral Amygdala, Stephanie K. Nygard, Nicholas J. Hourguettes, Gabe G. Sobczak, William A. Carlezon, Michael R. Bruchas

Open Access Publications

UNLABELLED: The dynorphin (DYN)/kappa-opioid receptor (KOR) system plays a conserved role in stress-induced reinstatement of drug seeking for prototypical substances of abuse. Due to nicotine's high propensity for stress-induced relapse, we hypothesized that stress would induce reinstatement of nicotine seeking-like behavior in a KOR-dependent manner. Using a conditioned place preference (CPP) reinstatement procedure in mice, we show that both foot-shock stress and the pharmacological stressor yohimbine (2 mg/kg, i.p.) induce reinstatement of nicotine CPP in a norbinaltorphimine (norBNI, a KOR antagonist)-sensitive manner, indicating that KOR activity is necessary for stress-induced nicotine CPP reinstatement. After reinstatement testing, we visualized robust c-fos …


Using Diffusion Tractography To Predict Cortical Connection Strength And Distance: A Quantitative Comparison With Tracers In The Monkey, Chad J. Donahue, Stamatios N. Sotiropoulos, Saad Jbabdi, Moises Hernandez-Fernandez, Timothy E. Behrens, Tim B. Dyrby, Timothy Coalson, Henry Kennedy, Kenneth Knoblauch, David C. Van Essen, Matthew F. Glasser Jun 2016

Using Diffusion Tractography To Predict Cortical Connection Strength And Distance: A Quantitative Comparison With Tracers In The Monkey, Chad J. Donahue, Stamatios N. Sotiropoulos, Saad Jbabdi, Moises Hernandez-Fernandez, Timothy E. Behrens, Tim B. Dyrby, Timothy Coalson, Henry Kennedy, Kenneth Knoblauch, David C. Van Essen, Matthew F. Glasser

Open Access Publications

UNLABELLED: Tractography based on diffusion MRI offers the promise of characterizing many aspects of long-distance connectivity in the brain, but requires quantitative validation to assess its strengths and limitations. Here, we evaluate tractography's ability to estimate the presence and strength of connections between areas of macaque neocortex by comparing its results with published data from retrograde tracer injections. Probabilistic tractography was performed on high-quality postmortem diffusion imaging scans from two Old World monkey brains. Tractography connection weights were estimated using a fractional scaling method based on normalized streamline density. We found a correlation between log-transformed tractography and tracer connection weights …


Asfotase Alfa Therapy For Children With Hypophosphatasia, Michael P. Whyte, Katherine L. Madson, Dawn Phillips, Amy L. Reeves, William H. Mcalister, Amy Yakimoski, Karen E. Mack, Kim Hamilton, Kori Kagan, Kenji P. Fujita, David D. Thompson, Scott Moseley, Tatjana Odrljin, Cheryl Rockman-Greenberg Jun 2016

Asfotase Alfa Therapy For Children With Hypophosphatasia, Michael P. Whyte, Katherine L. Madson, Dawn Phillips, Amy L. Reeves, William H. Mcalister, Amy Yakimoski, Karen E. Mack, Kim Hamilton, Kori Kagan, Kenji P. Fujita, David D. Thompson, Scott Moseley, Tatjana Odrljin, Cheryl Rockman-Greenberg

Open Access Publications

No abstract provided.


Aromatase Inhibition Remodels The Clonal Architecture Of Estrogen-Receptor-Positive Breast Cancers, Christopher A. Miller, Yevgeniy Gindin, Charles Lu, Obi L. Griffith, Malachi Griffith, Dong Shen, Jeremy Hoog, Tiandao Li, David E. Larson, Mark Watson, Sherri R. Davies, Jacqueline Snider, Thomas Walsh, Graham A. Colditz, Katherine Deschryver, Richard K. Wilson, Elaine R. Mardis, Matthew J. Ellis, Et Al Jan 2016

Aromatase Inhibition Remodels The Clonal Architecture Of Estrogen-Receptor-Positive Breast Cancers, Christopher A. Miller, Yevgeniy Gindin, Charles Lu, Obi L. Griffith, Malachi Griffith, Dong Shen, Jeremy Hoog, Tiandao Li, David E. Larson, Mark Watson, Sherri R. Davies, Jacqueline Snider, Thomas Walsh, Graham A. Colditz, Katherine Deschryver, Richard K. Wilson, Elaine R. Mardis, Matthew J. Ellis, Et Al

Open Access Publications

No abstract provided.


The Brief Case: Dyspnea In A Profoundly Immunocompromised Man, Andrej Spec, Carlos A.Q. Santos, Morgan A. Pence Jan 2016

The Brief Case: Dyspnea In A Profoundly Immunocompromised Man, Andrej Spec, Carlos A.Q. Santos, Morgan A. Pence

Open Access Publications

No abstract provided.