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Epigenetic Dysregulation Of Enhancers In Neurons Is Associated With Alzheimer’S Disease Pathology And Cognitive Symptoms, Peipei Li, Lee Marshall, Gabriel Oh, Jennifer L. Jakubowski, Daniel Groot, Yu He, Ting Wang, Arturas Petronis, Viviane Labrie Jan 2019

Epigenetic Dysregulation Of Enhancers In Neurons Is Associated With Alzheimer’S Disease Pathology And Cognitive Symptoms, Peipei Li, Lee Marshall, Gabriel Oh, Jennifer L. Jakubowski, Daniel Groot, Yu He, Ting Wang, Arturas Petronis, Viviane Labrie

Open Access Publications

No abstract provided.


Lncrna Malat1 Gene Polymorphisms In Coronary Artery Disease: A Case-Control Study In A Chinese Population, Weina Hu, Hanxi Ding, An Ouyang, Xiaohong Zhang, Qian Xu, Yunan Han, Xueying Zhang, Yuanzhe Jin Jan 2019

Lncrna Malat1 Gene Polymorphisms In Coronary Artery Disease: A Case-Control Study In A Chinese Population, Weina Hu, Hanxi Ding, An Ouyang, Xiaohong Zhang, Qian Xu, Yunan Han, Xueying Zhang, Yuanzhe Jin

Open Access Publications

No abstract provided.


The Peptide Hormone Adropin Regulates Signal Transduction Pathways Controlling Hepatic Glucose Metabolism In A Mouse Model Of Diet-Induced Obesity, Su Gao, Sarbani Ghoshal, Liyan Zhang, Joseph R. Stevens, Kyle S. Mccommis, Brian N. Finck, Gary D. Lopaschuk, Andrew A. Butler Jan 2019

The Peptide Hormone Adropin Regulates Signal Transduction Pathways Controlling Hepatic Glucose Metabolism In A Mouse Model Of Diet-Induced Obesity, Su Gao, Sarbani Ghoshal, Liyan Zhang, Joseph R. Stevens, Kyle S. Mccommis, Brian N. Finck, Gary D. Lopaschuk, Andrew A. Butler

Open Access Publications

No abstract provided.


Adaptation Of Translational Machinery In Malaria Parasites To Accommodate Translation Of Poly-Adenosine Stretches Throughout Its Life Cycle, Jessey Erath, Sergej Djuranovic, Slavica Pavlovic Djuranovic Jan 2019

Adaptation Of Translational Machinery In Malaria Parasites To Accommodate Translation Of Poly-Adenosine Stretches Throughout Its Life Cycle, Jessey Erath, Sergej Djuranovic, Slavica Pavlovic Djuranovic

Open Access Publications

Malaria is caused by unicellular apicomplexan parasites of the genus


Automation And Simplification: Drivers Of Innovative Collection And Use Of Patient-Reported Outcomes Data, Jason M. Guattery, Jimmy Johnson, Ryan P. Calfee Jan 2019

Automation And Simplification: Drivers Of Innovative Collection And Use Of Patient-Reported Outcomes Data, Jason M. Guattery, Jimmy Johnson, Ryan P. Calfee

Open Access Publications

No abstract provided.


Neuroinflammation And White Matter Alterations In Obesity Assessed By Diffusion Basis Spectrum Imaging, Amjad Samara, Tatianna Murphy, Jeremy Strain, Jerrel Rutlin, Peng Sun, Olga Neyman, Nitya Sreevalsan, Joshua S Shimony, Beau M Ances, Sheng-Kwei Song, Tamara Hershey, Sarah A Eisenstein Jan 2019

Neuroinflammation And White Matter Alterations In Obesity Assessed By Diffusion Basis Spectrum Imaging, Amjad Samara, Tatianna Murphy, Jeremy Strain, Jerrel Rutlin, Peng Sun, Olga Neyman, Nitya Sreevalsan, Joshua S Shimony, Beau M Ances, Sheng-Kwei Song, Tamara Hershey, Sarah A Eisenstein

Open Access Publications

Human obesity is associated with low-grade chronic systemic inflammation, alterations in brain structure and function, and cognitive impairment. Rodent models of obesity show that high-calorie diets cause brain inflammation (neuroinflammation) in multiple regions, including the hippocampus, and impairments in hippocampal-dependent memory tasks. To determine if similar effects exist in humans with obesity, we applied Diffusion Basis Spectrum Imaging (DBSI) to evaluate neuroinflammation and axonal integrity. We examined diffusion-weighted magnetic resonance imaging (MRI) data in two independent cohorts of obese and non-obese individuals (Cohort 1: 25 obese/21 non-obese; Cohort 2: 18 obese/41 non-obese). We applied Tract-based Spatial Statistics (TBSS) to allow …


A Fully Magnetically Levitated Left Ventricular Assist Device — Final Report, G.A. Ewald, A. Itoh Jan 2019

A Fully Magnetically Levitated Left Ventricular Assist Device — Final Report, G.A. Ewald, A. Itoh

Open Access Publications

No abstract provided.


Quantitative 18f-Av1451 Brain Tau Pet Imaging In Cognitively Normal Older Adults, Mild Cognitive Impairment, And Alzheimer's Disease Patients, Qian Zhao, Min Liu, Lingxia Ha, Yun Zhou, Alzheimer's Disease Neuroimaging Initiative Jan 2019

Quantitative 18f-Av1451 Brain Tau Pet Imaging In Cognitively Normal Older Adults, Mild Cognitive Impairment, And Alzheimer's Disease Patients, Qian Zhao, Min Liu, Lingxia Ha, Yun Zhou, Alzheimer's Disease Neuroimaging Initiative

Open Access Publications

No abstract provided.


Kiaa1549-Braf Expression Establishes A Permissive Tumor Microenvironment Through Nfκb-Mediated Ccl2 Production, Ran Chen, Chanel Keoni, Christopher A. Waker, Robert M. Lober, David H. Gutmann Jan 2019

Kiaa1549-Braf Expression Establishes A Permissive Tumor Microenvironment Through Nfκb-Mediated Ccl2 Production, Ran Chen, Chanel Keoni, Christopher A. Waker, Robert M. Lober, David H. Gutmann

Open Access Publications

No abstract provided.


Genetic Basis Of Variation In Heat And Ethanol Tolerance In Saccharomyces Cerevisiae, Linda Riles, Justin C. Fay Jan 2019

Genetic Basis Of Variation In Heat And Ethanol Tolerance In Saccharomyces Cerevisiae, Linda Riles, Justin C. Fay

Open Access Publications

No abstract provided.


Endothelial Glycocalyx: Role In Body Fluid Homeostasis And Fluid Management, Pankaj Kundra, Shreya Goswami Jan 2019

Endothelial Glycocalyx: Role In Body Fluid Homeostasis And Fluid Management, Pankaj Kundra, Shreya Goswami

Open Access Publications

No abstract provided.


Independent Associations Of Tomm40 And Apoe Variants With Body Mass Index, Alexander M. Kulminski, Yury Loika, Irina Culminskaya, Jian Huang, Konstantin G. Arbeev, Olivia Bagley, Mary F. Feitosa, Joseph M. Zmuda, Kaare Christensen, Anatoliy I. Yashin, Long Life Family Study Research Group Jan 2019

Independent Associations Of Tomm40 And Apoe Variants With Body Mass Index, Alexander M. Kulminski, Yury Loika, Irina Culminskaya, Jian Huang, Konstantin G. Arbeev, Olivia Bagley, Mary F. Feitosa, Joseph M. Zmuda, Kaare Christensen, Anatoliy I. Yashin, Long Life Family Study Research Group

Open Access Publications

No abstract provided.


Parkinson's Disease And Multiple System Atrophy Have Distinct Α-Synuclein Seed Characteristics, Tritia R. Yamasaki, Brandon B. Holmes, Jennifer L. Furman, Dhruva D. Dhavale, Bryant W. Su, Eun-Suk Song, Nigel J. Cairns, Paul T. Kotzbauer, Marc I. Diamond Jan 2019

Parkinson's Disease And Multiple System Atrophy Have Distinct Α-Synuclein Seed Characteristics, Tritia R. Yamasaki, Brandon B. Holmes, Jennifer L. Furman, Dhruva D. Dhavale, Bryant W. Su, Eun-Suk Song, Nigel J. Cairns, Paul T. Kotzbauer, Marc I. Diamond

Open Access Publications

No abstract provided.


Doubled Lifespan And Patient‐Like Pathologies In Progeria Mice Fed High‐Fat Diet, Ray Kreienkamp, Cyrielle Billon, Gonzalo Bedia-Diaz, Carolyn J. Albert, Zacharie Toth, Andrew A. Butler, Sara Mcbride-Gagyi, David A. Ford, Angel Baldan, Thomas P. Burris, Susana Gonzalo Jan 2019

Doubled Lifespan And Patient‐Like Pathologies In Progeria Mice Fed High‐Fat Diet, Ray Kreienkamp, Cyrielle Billon, Gonzalo Bedia-Diaz, Carolyn J. Albert, Zacharie Toth, Andrew A. Butler, Sara Mcbride-Gagyi, David A. Ford, Angel Baldan, Thomas P. Burris, Susana Gonzalo

Open Access Publications

No abstract provided.


Persistent Metabolic Youth In The Aging Female Brain, Manu S. Goyal, Tyler M. Blazey, Yi Su, Lars E. Couture, Tony J. Durbin, Randall J. Bateman, Tammie L.-S. Benzinger, John C. Morris, Marcus E. Raichle, Andrei G. Vlassenko Jan 2019

Persistent Metabolic Youth In The Aging Female Brain, Manu S. Goyal, Tyler M. Blazey, Yi Su, Lars E. Couture, Tony J. Durbin, Randall J. Bateman, Tammie L.-S. Benzinger, John C. Morris, Marcus E. Raichle, Andrei G. Vlassenko

Open Access Publications

No abstract provided.


Cells Exhibiting Strong P16ink4a Promoter Activation In Vivo Display Features Of Senescence, Jie-Yu Liu, George P. Souroullas, Brian O. Diekman, Janakiraman Krishnamurthy, Brandon M. Hall, Jessica A. Sorrentino, Joel S. Parker, Garrett A. Sessions, Andrei V. Gudkov, Norman E. Sharpless Jan 2019

Cells Exhibiting Strong P16ink4a Promoter Activation In Vivo Display Features Of Senescence, Jie-Yu Liu, George P. Souroullas, Brian O. Diekman, Janakiraman Krishnamurthy, Brandon M. Hall, Jessica A. Sorrentino, Joel S. Parker, Garrett A. Sessions, Andrei V. Gudkov, Norman E. Sharpless

Open Access Publications

No abstract provided.


Guide Positioning Sequencing Identifies Aberrant Dna Methylation Patterns That Alter Cell Identity And Tumor-Immune Surveillance Networks, Ting Wang, Et Al Jan 2019

Guide Positioning Sequencing Identifies Aberrant Dna Methylation Patterns That Alter Cell Identity And Tumor-Immune Surveillance Networks, Ting Wang, Et Al

Open Access Publications

No abstract provided.


Baseline And Interim Functional Imaging With Pet Effectively Risk Stratifies Patients With Peripheral T-Cell Lymphoma, Neha Mehta-Shah, Kimiteru Ito, Kurt Bantilan, Alison J. Moskowitz, Craig Sauter, Steven M. Horwitz, Heiko Schoder Jan 2019

Baseline And Interim Functional Imaging With Pet Effectively Risk Stratifies Patients With Peripheral T-Cell Lymphoma, Neha Mehta-Shah, Kimiteru Ito, Kurt Bantilan, Alison J. Moskowitz, Craig Sauter, Steven M. Horwitz, Heiko Schoder

Open Access Publications

No abstract provided.


Post Hoc Analyses Of Surrogate Markers Of Non-Alcoholic Fatty Liver Disease (Nafld) And Liver Fibrosis In Patients With Type 2 Diabetes In A Digitally Supported Continuous Care Intervention: An Open-Label, Non-Randomised Controlled Study, Eduardo Vilar-Gomez, Shaminie J. Athinarayanan, Rebecca N. Adams, Sarah J. Hallberg, Nasir H. Bhanpuri, Amy L. Mckenzie, Wayne W. Campbell, James P. Mccarter, Stephen D. Phinney, Jeff S. Volek, Naga Chalasani Jan 2019

Post Hoc Analyses Of Surrogate Markers Of Non-Alcoholic Fatty Liver Disease (Nafld) And Liver Fibrosis In Patients With Type 2 Diabetes In A Digitally Supported Continuous Care Intervention: An Open-Label, Non-Randomised Controlled Study, Eduardo Vilar-Gomez, Shaminie J. Athinarayanan, Rebecca N. Adams, Sarah J. Hallberg, Nasir H. Bhanpuri, Amy L. Mckenzie, Wayne W. Campbell, James P. Mccarter, Stephen D. Phinney, Jeff S. Volek, Naga Chalasani

Open Access Publications

No abstract provided.


Transcription Factor Eb Activation Rescues Advanced Αb-Crystallin Mutation-Induced Cardiomyopathy By Normalizing Desmin Localization, Xiucui Ma, Kartik Mani, Haiyan Liu, Attila Kovacs, John T. Murphy, Layla Foroughi, Brent A. French, Carla J. Weinheimer, Aldi Kraja, Ivor J. Benjamin, Joseph A. Hill, Ali Javeheri, Abhinav Diwan Jan 2019

Transcription Factor Eb Activation Rescues Advanced Αb-Crystallin Mutation-Induced Cardiomyopathy By Normalizing Desmin Localization, Xiucui Ma, Kartik Mani, Haiyan Liu, Attila Kovacs, John T. Murphy, Layla Foroughi, Brent A. French, Carla J. Weinheimer, Aldi Kraja, Ivor J. Benjamin, Joseph A. Hill, Ali Javeheri, Abhinav Diwan

Open Access Publications

No abstract provided.


Symbiotic Organs Shaped By Distinct Modes Of Genome Evolution In Cephalopods, Patrick Minx Jan 2019

Symbiotic Organs Shaped By Distinct Modes Of Genome Evolution In Cephalopods, Patrick Minx

Open Access Publications

No abstract provided.


Implementation Of The Healthy Workplace Participatory Program In A Retail Setting: A Feasibility Study And Framework For Evaluation, Jaime R. Strickland, Anna M. Kinghorn, Bradley A. Evanoff, Ann M. Dale Jan 2019

Implementation Of The Healthy Workplace Participatory Program In A Retail Setting: A Feasibility Study And Framework For Evaluation, Jaime R. Strickland, Anna M. Kinghorn, Bradley A. Evanoff, Ann M. Dale

Open Access Publications

No abstract provided.


Consumption Of Animal-Source Protein Is Associated With Improved Height-For-Age Z Scores In Rural Malawian Children Aged 12–36 Months, Yankho Kaimila, Oscar Divala, Sophia E. Agapova, Kevin B. Stephenson, Chrissie Thakwalakwa, Indi Trehan, Mark J. Manary, Kenneth M. Maleta Jan 2019

Consumption Of Animal-Source Protein Is Associated With Improved Height-For-Age Z Scores In Rural Malawian Children Aged 12–36 Months, Yankho Kaimila, Oscar Divala, Sophia E. Agapova, Kevin B. Stephenson, Chrissie Thakwalakwa, Indi Trehan, Mark J. Manary, Kenneth M. Maleta

Open Access Publications

No abstract provided.


Whole-Genome Sequencing Of Klebsiella Pneumoniae Isolates To Track Strain Progression In A Single Patient With Recurrent Urinary Tract Infection, Kristine M. Wylie, Todd N. Wylie, Patrick J. Minx, David A. Rosen Jan 2019

Whole-Genome Sequencing Of Klebsiella Pneumoniae Isolates To Track Strain Progression In A Single Patient With Recurrent Urinary Tract Infection, Kristine M. Wylie, Todd N. Wylie, Patrick J. Minx, David A. Rosen

Open Access Publications

No abstract provided.


A Hypothesis-Generating Study Of The Combination Of Aspirin Plus Macrolides In Patients With Severe Community-Acquired Pneumonia, Christopher Jones, Marin Kollef, Et Al Jan 2019

A Hypothesis-Generating Study Of The Combination Of Aspirin Plus Macrolides In Patients With Severe Community-Acquired Pneumonia, Christopher Jones, Marin Kollef, Et Al

Open Access Publications

No abstract provided.


Predictive Role Of Symptom Duration Before The Initial Clinical Presentation Of Adolescents With Capitellar Osteochondritis Dissecans On Preoperative And Postoperative Measures: A Systematic Review, Christopher Cheng, Matthew D. Milewski, Jeffrey J. Nepple, Hannah S. Reuman, Carl W. Nissen Jan 2019

Predictive Role Of Symptom Duration Before The Initial Clinical Presentation Of Adolescents With Capitellar Osteochondritis Dissecans On Preoperative And Postoperative Measures: A Systematic Review, Christopher Cheng, Matthew D. Milewski, Jeffrey J. Nepple, Hannah S. Reuman, Carl W. Nissen

Open Access Publications

No abstract provided.


The Comparative Genomics And Complex Population History Of Papio Baboons, Jane Phillips-Conroy, Et Al Jan 2019

The Comparative Genomics And Complex Population History Of Papio Baboons, Jane Phillips-Conroy, Et Al

Open Access Publications

No abstract provided.


Mitochondrial Dna And Temperature Tolerance In Lager Yeasts, Emilyclare P. Baker, David Peris, Ryan V. Moriarty, Xueying C. Li, Justin C. Fay, Chris T. Hittinger Jan 2019

Mitochondrial Dna And Temperature Tolerance In Lager Yeasts, Emilyclare P. Baker, David Peris, Ryan V. Moriarty, Xueying C. Li, Justin C. Fay, Chris T. Hittinger

Open Access Publications

No abstract provided.


Operative Versus Nonoperative Treatment For Adult Symptomatic Lumbar Scoliosis, Michael P. Kelly, Elizabeth L. Yanik, Christine R. Baldus, Jacob M. Buchowski, Munish C. Gupta, Lukas P. Zebala, Keith H. Bridwell, Et Al Jan 2019

Operative Versus Nonoperative Treatment For Adult Symptomatic Lumbar Scoliosis, Michael P. Kelly, Elizabeth L. Yanik, Christine R. Baldus, Jacob M. Buchowski, Munish C. Gupta, Lukas P. Zebala, Keith H. Bridwell, Et Al

Open Access Publications

No abstract provided.


Single-Nucleotide Human Disease Mutation Inactivates A Blood-Regenerative Gata2 Enhancer, Alexandra A. Soukup, Ye Zheng, Charu Mahta, Jun Wu, Peng Liu, Miao Cao, Inga Hofmann, Yun Zhou, Jing Zhang, Kirby D. Johnson, Kyunghee Choi, Sunduz Keles, Emery H. Bresnick Jan 2019

Single-Nucleotide Human Disease Mutation Inactivates A Blood-Regenerative Gata2 Enhancer, Alexandra A. Soukup, Ye Zheng, Charu Mahta, Jun Wu, Peng Liu, Miao Cao, Inga Hofmann, Yun Zhou, Jing Zhang, Kirby D. Johnson, Kyunghee Choi, Sunduz Keles, Emery H. Bresnick

Open Access Publications

No abstract provided.