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Articles 2251 - 2280 of 4253
Full-Text Articles in Entire DC Network
A Clickable Analogue Of Ketamine Retains Nmda Receptor Activity, Psychoactivity, And Accumulates In Neurons, Christine Emnett, Hairong Li, Xiaoping Jiang, Ann Benz, Joseph Boggiano, Sara Conyers, David F. Wozniak, Charles F. Zorumski, David E. Reichert, Steven Mennerick
A Clickable Analogue Of Ketamine Retains Nmda Receptor Activity, Psychoactivity, And Accumulates In Neurons, Christine Emnett, Hairong Li, Xiaoping Jiang, Ann Benz, Joseph Boggiano, Sara Conyers, David F. Wozniak, Charles F. Zorumski, David E. Reichert, Steven Mennerick
Open Access Publications
No abstract provided.
Soluble Amyloid-Beta Aggregates From Human Alzheimer's Disease Brains, Thomas J. Esparza, Norelle C. Wildburger, Hao Jiang, Mihika Gangolli, Nigel J. Cairns, Randall J. Bateman, David L. Brody
Soluble Amyloid-Beta Aggregates From Human Alzheimer's Disease Brains, Thomas J. Esparza, Norelle C. Wildburger, Hao Jiang, Mihika Gangolli, Nigel J. Cairns, Randall J. Bateman, David L. Brody
Open Access Publications
No abstract provided.
Cox-2 Inhibition Reduces Brucella Bacterial Burden In Draining Lymph Nodes, Aurelie Gagnaire, Laurent Gorvel, Alexia Papadopoulos, Kristine Von Bargen, Jean-Louis Mege, Jean-Pierre Gorvel
Cox-2 Inhibition Reduces Brucella Bacterial Burden In Draining Lymph Nodes, Aurelie Gagnaire, Laurent Gorvel, Alexia Papadopoulos, Kristine Von Bargen, Jean-Louis Mege, Jean-Pierre Gorvel
Open Access Publications
No abstract provided.
Atg16l1 Governs Placental Infection Risk And Preterm Birth In Mice And Women, Bin Cao, Colin Macones, Indira U. Mysorekar
Atg16l1 Governs Placental Infection Risk And Preterm Birth In Mice And Women, Bin Cao, Colin Macones, Indira U. Mysorekar
Open Access Publications
No abstract provided.
Regenerated Sciatic Nerve Axons Stimulated Through A Chronically Implanted Macro-Sieve Electrode, Matthew R. Macewan, Erik R. Zellmer, Jesse J. Wheeler, Harold Burton, Daniel W. Moran
Regenerated Sciatic Nerve Axons Stimulated Through A Chronically Implanted Macro-Sieve Electrode, Matthew R. Macewan, Erik R. Zellmer, Jesse J. Wheeler, Harold Burton, Daniel W. Moran
Open Access Publications
No abstract provided.
Rpl13a Small Nucleolar Rnas Regulate Systemic Glucose Metabolism, Jiyeon Lee, Alexis N. Harris, Christopher L. Holley, Jana Mahadevan, Kelly D. Pyles, Zeno Lavagnino, David E. Scherrer, Hideji Fujiwara, Rohini Sidhu, Jessie Zhang, Stanley Ching-Cheng Huang, David W. Piston, Maria S. Remedi, Fumihiko Urano, Daniel S. Ory, Jean E. Schaffer
Rpl13a Small Nucleolar Rnas Regulate Systemic Glucose Metabolism, Jiyeon Lee, Alexis N. Harris, Christopher L. Holley, Jana Mahadevan, Kelly D. Pyles, Zeno Lavagnino, David E. Scherrer, Hideji Fujiwara, Rohini Sidhu, Jessie Zhang, Stanley Ching-Cheng Huang, David W. Piston, Maria S. Remedi, Fumihiko Urano, Daniel S. Ory, Jean E. Schaffer
Open Access Publications
No abstract provided.
Somatic Variants In The Human Lens Epithelium: A Preliminary Assessment, Rosana Mesa, Manoj Tyagi, George Harocopos, David Vollman, Steven Bassnett
Somatic Variants In The Human Lens Epithelium: A Preliminary Assessment, Rosana Mesa, Manoj Tyagi, George Harocopos, David Vollman, Steven Bassnett
Open Access Publications
No abstract provided.
Crxrdy Cat: A Large Animal Model For Crx-Associated Leber Congenital Amaurosis, Laurence M. Occelli, Nicholas M. Tran, Kristina Narfstrom, Shiming Chen, Simon M. Peteresen-Jones
Crxrdy Cat: A Large Animal Model For Crx-Associated Leber Congenital Amaurosis, Laurence M. Occelli, Nicholas M. Tran, Kristina Narfstrom, Shiming Chen, Simon M. Peteresen-Jones
Open Access Publications
No abstract provided.
Full-Thickness Wound Healing Using 3d Bioprinted Gelatin-Alginate Scaffolds In Mice: A Histopathological Study, Jing Liu, Jinghua Chi, Kaixi Wang, Xiaoping Liu, Jie Liu, Fang Gu
Full-Thickness Wound Healing Using 3d Bioprinted Gelatin-Alginate Scaffolds In Mice: A Histopathological Study, Jing Liu, Jinghua Chi, Kaixi Wang, Xiaoping Liu, Jie Liu, Fang Gu
Open Access Publications
No abstract provided.
Blood Lipids And Prostate Cancer: A Mendelian Randomization Analysis, Adam S. Kibel, Et Al
Blood Lipids And Prostate Cancer: A Mendelian Randomization Analysis, Adam S. Kibel, Et Al
Open Access Publications
No abstract provided.
Dendritic Mitochondria Reach Stable Positions During Circuit Development, Michelle C. Faits, Chunmeng Zhang, Florentina Soto, Daniel Kerschensteiner
Dendritic Mitochondria Reach Stable Positions During Circuit Development, Michelle C. Faits, Chunmeng Zhang, Florentina Soto, Daniel Kerschensteiner
Open Access Publications
No abstract provided.
Drh1, A P68-Related Rna Helicase Gene, Is Required For Chromosome Breakage In Tetrahymena, Stephen L. Mcdaniel, Erica Zweifel, Peter K. W. Harris, Meng-Chao Yao, Eric S. Cole, Douglas L. Chalker
Drh1, A P68-Related Rna Helicase Gene, Is Required For Chromosome Breakage In Tetrahymena, Stephen L. Mcdaniel, Erica Zweifel, Peter K. W. Harris, Meng-Chao Yao, Eric S. Cole, Douglas L. Chalker
Open Access Publications
No abstract provided.
Polarization Of Macrophages Toward M2 Phenotype Is Favored By Reduction In Ipla2Β (Group Via Phospholipase A2)*, Jason W. Ashley, William D. Hancock, Alexander J. Nelson, Robert N. Bone, Hubert M. Tse, Mary Wohltmann, John Turk, Sasanka Ramanadham
Polarization Of Macrophages Toward M2 Phenotype Is Favored By Reduction In Ipla2Β (Group Via Phospholipase A2)*, Jason W. Ashley, William D. Hancock, Alexander J. Nelson, Robert N. Bone, Hubert M. Tse, Mary Wohltmann, John Turk, Sasanka Ramanadham
Open Access Publications
No abstract provided.
Major Role Of Adipocyte Prostaglandin E2 In Lipolysis-Induced Macrophage Recruitment, Xiaoqian Hu, Vincenza Cifarelli, Shishuo Sun, Ondrej Kuda, Nada A. Abumrad, Xiong Su
Major Role Of Adipocyte Prostaglandin E2 In Lipolysis-Induced Macrophage Recruitment, Xiaoqian Hu, Vincenza Cifarelli, Shishuo Sun, Ondrej Kuda, Nada A. Abumrad, Xiong Su
Open Access Publications
No abstract provided.
Sevoflurane Alters Spatiotemporal Functional Connectivity Motifs That Link Resting-State Networks During Wakefulness, Mohammadmehdi Kafashan, Shinung Ching, Ben J.A. Palanca
Sevoflurane Alters Spatiotemporal Functional Connectivity Motifs That Link Resting-State Networks During Wakefulness, Mohammadmehdi Kafashan, Shinung Ching, Ben J.A. Palanca
Open Access Publications
No abstract provided.
Rab43 Facilitates Cross-Presentation Of Cell-Associated Antigens By Cd8 Alpha(+) Dendritic Cells, Nicole M. Kretzer, Derek J. Theisen, Roxane Tussiwand, Carlos G. Briseno, Gary E. Grajales-Reyes, Xiaodi Wu, Vivek Durai, Jorn Albring, Prachi Bagadia, Theresa L. Murphy, Kenneth M. Murphy
Rab43 Facilitates Cross-Presentation Of Cell-Associated Antigens By Cd8 Alpha(+) Dendritic Cells, Nicole M. Kretzer, Derek J. Theisen, Roxane Tussiwand, Carlos G. Briseno, Gary E. Grajales-Reyes, Xiaodi Wu, Vivek Durai, Jorn Albring, Prachi Bagadia, Theresa L. Murphy, Kenneth M. Murphy
Open Access Publications
No abstract provided.
Elevated Fibroblast Growth Factor Signaling Is Critical For The Pathogenesis Of The Dwarfism In Evc2/Limbin Mutant Mice, Honghao Zhang, Nobuhiro Kamiya, Takehito Tsuji, Haruko Takeda, Greg Scott, Sudha Rajderkar, Manas K. Ray, Yoshiyuki Mochida, Benjamin Allen, Veronique Lefebvre, Irene H. Hung, David M. Omitz, Tetsuo Kunieda, Yuji Mishina
Elevated Fibroblast Growth Factor Signaling Is Critical For The Pathogenesis Of The Dwarfism In Evc2/Limbin Mutant Mice, Honghao Zhang, Nobuhiro Kamiya, Takehito Tsuji, Haruko Takeda, Greg Scott, Sudha Rajderkar, Manas K. Ray, Yoshiyuki Mochida, Benjamin Allen, Veronique Lefebvre, Irene H. Hung, David M. Omitz, Tetsuo Kunieda, Yuji Mishina
Open Access Publications
No abstract provided.
Distinct Firing Properties Of Vasoactive Intestinal Peptide-Expressing Neurons In The Suprachiasmatic Nucleus, Tracey O. Hermanstyne, Carrie L. Simms, Yarimar Carrasquillo, Erik D. Herzog, Jeanne M. Nerbonne
Distinct Firing Properties Of Vasoactive Intestinal Peptide-Expressing Neurons In The Suprachiasmatic Nucleus, Tracey O. Hermanstyne, Carrie L. Simms, Yarimar Carrasquillo, Erik D. Herzog, Jeanne M. Nerbonne
Open Access Publications
No abstract provided.
Cmtm2 Is Essential For Spermiogenesis In Mice, Xiaowei Zhang, Zhe Chen, Nannan Huang, Ling Kuang, Huaqi Yin, Ke Lan, Qing Li, Yongping Zhao, Kite Brandes, Tao Xu
Cmtm2 Is Essential For Spermiogenesis In Mice, Xiaowei Zhang, Zhe Chen, Nannan Huang, Ling Kuang, Huaqi Yin, Ke Lan, Qing Li, Yongping Zhao, Kite Brandes, Tao Xu
Open Access Publications
No abstract provided.
A Critical Review Of Perfluorooctanoate And Perfluorooctanesulfonate Exposure And Immunological Health Conditions In Humans, Ellen T. Chang, Hans-Olov Adami, Paolo Boffetta, H. James Wedner, Jack S. Mandel
A Critical Review Of Perfluorooctanoate And Perfluorooctanesulfonate Exposure And Immunological Health Conditions In Humans, Ellen T. Chang, Hans-Olov Adami, Paolo Boffetta, H. James Wedner, Jack S. Mandel
Open Access Publications
No abstract provided.
Pilot Clinical Observations Between Food And Drug Seeking Derived From Fifty Cases Attending An Eating Disorder Clinic, Harriet Beitscher-Campbell, Kenneth Blum, Marcelo Febo, Margaret A. Madigan, John Giordano, Rajendra D. Badgaiyan, Eric R. Braverman, Kristina Dushaj, Mona Li, Mark S. Gold
Pilot Clinical Observations Between Food And Drug Seeking Derived From Fifty Cases Attending An Eating Disorder Clinic, Harriet Beitscher-Campbell, Kenneth Blum, Marcelo Febo, Margaret A. Madigan, John Giordano, Rajendra D. Badgaiyan, Eric R. Braverman, Kristina Dushaj, Mona Li, Mark S. Gold
Open Access Publications
No abstract provided.
Advances In Cholangiocarcinoma Research: Report From The Third Cholangiocarcinoma Foundation Annual Conference, William Chapman, Et Al
Advances In Cholangiocarcinoma Research: Report From The Third Cholangiocarcinoma Foundation Annual Conference, William Chapman, Et Al
Open Access Publications
No abstract provided.
Finely Tuned Temporal And Spatial Delivery Of Gdnf Promotes Enhanced Nerve Regeneration In A Long Nerve Defect Model, Laura M. Marquardt, Xueping Ee, Nisha Iyer, Daniel Hunter, Susan E. Mackinnon, Matthew D. Wood, Shelly E. Sakiyama-Elbert
Finely Tuned Temporal And Spatial Delivery Of Gdnf Promotes Enhanced Nerve Regeneration In A Long Nerve Defect Model, Laura M. Marquardt, Xueping Ee, Nisha Iyer, Daniel Hunter, Susan E. Mackinnon, Matthew D. Wood, Shelly E. Sakiyama-Elbert
Open Access Publications
No abstract provided.
Progressive Hearing Loss In Mice Carrying A Mutation In Usp53, Marcin Kazmierczak, Suzan L. Harris, Piotr Kazmierczak, Prahar Shah, Valentin Starovoytov, Kevin K. Ohlemiller, Martin Schwander
Progressive Hearing Loss In Mice Carrying A Mutation In Usp53, Marcin Kazmierczak, Suzan L. Harris, Piotr Kazmierczak, Prahar Shah, Valentin Starovoytov, Kevin K. Ohlemiller, Martin Schwander
Open Access Publications
UNLABELLED: Disordered protein ubiquitination has been linked to neurodegenerative disease, yet its role in inner ear homeostasis and hearing loss is essentially unknown. Here we show that progressive hearing loss in the ethylnitrosourea-generated mambo mouse line is caused by a mutation in Usp53, a member of the deubiquitinating enzyme family. USP53 contains a catalytically inactive ubiquitin-specific protease domain and is expressed in cochlear hair cells and a subset of supporting cells. Although hair cell differentiation is unaffected in mambo mice, outer hair cells degenerate rapidly after the first postnatal week. USP53 colocalizes and interacts with the tight junction scaffolding proteins …
In Vivo Evaluation Of Adipose-Derived Stromal Cells Delivered With A Nanofiber Scaffold For Tendon-To-Bone Repair, Justin Lipner, Hua Shen, Leonardo Cavinatto, Wenying Liu, Necat Havlioglu, Younan Xia, Leesa M. Galatz, Stavros Thomopoulos
In Vivo Evaluation Of Adipose-Derived Stromal Cells Delivered With A Nanofiber Scaffold For Tendon-To-Bone Repair, Justin Lipner, Hua Shen, Leonardo Cavinatto, Wenying Liu, Necat Havlioglu, Younan Xia, Leesa M. Galatz, Stavros Thomopoulos
Open Access Publications
No abstract provided.
Propagated Infra-Slow Intrinsic Brain Activity Reorganizes Across Wake And Slow Wave Sleep, Anish Mitra, Abraham Z. Snyder, Enzo Tagliazucchi, Helmut Laufs, Marcus E. Raichle
Propagated Infra-Slow Intrinsic Brain Activity Reorganizes Across Wake And Slow Wave Sleep, Anish Mitra, Abraham Z. Snyder, Enzo Tagliazucchi, Helmut Laufs, Marcus E. Raichle
Open Access Publications
Propagation of slow intrinsic brain activity has been widely observed in electrophysiogical studies of slow wave sleep (SWS). However, in human resting state fMRI (rs-fMRI), intrinsic activity has been understood predominantly in terms of zero-lag temporal synchrony (functional connectivity) within systems known as resting state networks (RSNs). Prior rs-fMRI studies have found that RSNs are generally preserved across wake and sleep. Here, we use a recently developed analysis technique to study propagation of infra-slow intrinsic blood oxygen level dependent (BOLD) signals in normal adults during wake and SWS. This analysis reveals marked changes in propagation patterns in SWS vs. wake. …
Human And Murine Ifit1 Proteins Do Not Restrict Infection Of Negative-Sense Rna Viruses Of The Orthomyxoviridae, Bunyaviridae, And Filoviridae Families, Amelia K. Pinto, Graham D. Williams, Kristy J. Szretter, James P. White, José Luiz Proença-Módena, Gai Liu, Judith Olejnik, James D. Brien, Hideki Ebihara, Elke Mühlberger, Gaya Amarasinghe, Michael S. Diamond, Adrianus C.M. Boon
Human And Murine Ifit1 Proteins Do Not Restrict Infection Of Negative-Sense Rna Viruses Of The Orthomyxoviridae, Bunyaviridae, And Filoviridae Families, Amelia K. Pinto, Graham D. Williams, Kristy J. Szretter, James P. White, José Luiz Proença-Módena, Gai Liu, Judith Olejnik, James D. Brien, Hideki Ebihara, Elke Mühlberger, Gaya Amarasinghe, Michael S. Diamond, Adrianus C.M. Boon
Open Access Publications
UNLABELLED: Interferon-induced protein with tetratricopeptide repeats 1 (IFIT1) is a host protein with reported cell-intrinsic antiviral activity against several RNA viruses. The proposed basis for the activity against negative-sense RNA viruses is the binding to exposed 5'-triphosphates (5'-ppp) on the genome of viral RNA. However, recent studies reported relatively low binding affinities of IFIT1 for 5'-ppp RNA, suggesting that IFIT1 may not interact efficiently with this moiety under physiological conditions. To evaluate the ability of IFIT1 to have an impact on negative-sense RNA viruses, we infected Ifit1(-/-) and wild-type control mice and primary cells with four negative-sense RNA viruses (influenza …
Hepatocyte Growth Factor And Met Support Mouse Enteric Nervous System Development, The Peristaltic Response, And Intestinal Epithelial Proliferation In Response To Injury, Marina Avetisyan, Hongtao Wang, Ellen Merrick Schill, Saya Bery, John R. Grider, John A. Hassell, Thaddeus Stappenbeck, Robert O. Heuckeroth
Hepatocyte Growth Factor And Met Support Mouse Enteric Nervous System Development, The Peristaltic Response, And Intestinal Epithelial Proliferation In Response To Injury, Marina Avetisyan, Hongtao Wang, Ellen Merrick Schill, Saya Bery, John R. Grider, John A. Hassell, Thaddeus Stappenbeck, Robert O. Heuckeroth
Open Access Publications
UNLABELLED: Factors providing trophic support to diverse enteric neuron subtypes remain poorly understood. We tested the hypothesis that hepatocyte growth factor (HGF) and the HGF receptor MET might support some types of enteric neurons. HGF and MET are expressed in fetal and adult enteric nervous system. In vitro, HGF increased enteric neuron differentiation and neurite length, but only if vanishingly small amounts (1 pg/ml) of glial cell line-derived neurotrophic factor were included in culture media. HGF effects were blocked by phosphatidylinositol-3 kinase inhibitor and by MET-blocking antibody. Both of these inhibitors and MEK inhibition reduced neurite length. In adult mice, …
Temperatures Achieved In Human And Canine Neocortex During Intraoperative Passive Or Active Focal Cooling, Matthew D. Smyth, Rowland H. Han, Chester K. Yarbrough, Edward E. Patterson, Xiao-Feng Yang, John W. Miller, Steven M. Rothman, Raimondo D'Ambrosio
Temperatures Achieved In Human And Canine Neocortex During Intraoperative Passive Or Active Focal Cooling, Matthew D. Smyth, Rowland H. Han, Chester K. Yarbrough, Edward E. Patterson, Xiao-Feng Yang, John W. Miller, Steven M. Rothman, Raimondo D'Ambrosio
Open Access Publications
No abstract provided.
Selective Deletion Of Cochlear Hair Cells Causes Rapid Age-Dependent Changes In Spiral Ganglion And Cochlear Nucleus Neurons, Ling Tong, Melissa K. Strong, Tejbeer Kaur, Jose M. Juiz, Elizabeth C. Oesterle, Clifford Hume, Mark E. Warchol, Richard D. Palmiter, Edwin W. Rubel
Selective Deletion Of Cochlear Hair Cells Causes Rapid Age-Dependent Changes In Spiral Ganglion And Cochlear Nucleus Neurons, Ling Tong, Melissa K. Strong, Tejbeer Kaur, Jose M. Juiz, Elizabeth C. Oesterle, Clifford Hume, Mark E. Warchol, Richard D. Palmiter, Edwin W. Rubel
Open Access Publications
During nervous system development, critical periods are usually defined as early periods during which manipulations dramatically change neuronal structure or function, whereas the same manipulations in mature animals have little or no effect on the same property. Neurons in the ventral cochlear nucleus (CN) are dependent on excitatory afferent input for survival during a critical period of development. Cochlear removal in young mammals and birds results in rapid death of target neurons in the CN. Cochlear removal in older animals results in little or no neuron death. However, the extent to which hair-cell-specific afferent activity prevents neuronal death in the …