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Improved Performance Of A Rapid Immunochromatographic Assay For Detection Of Pbp2a In Non-Staphylococcus Aureus Staphylococcal Species, Matthew C. Canver, Mark D. Gonzalez, Bradley A. Ford, Amanda R. Arnold, Sara D. Lawhon, Carey-Ann D. Burnham, Stephen G. Jenkins, Eileen M. Burd, Lars F. Westblade Jan 2019

Improved Performance Of A Rapid Immunochromatographic Assay For Detection Of Pbp2a In Non-Staphylococcus Aureus Staphylococcal Species, Matthew C. Canver, Mark D. Gonzalez, Bradley A. Ford, Amanda R. Arnold, Sara D. Lawhon, Carey-Ann D. Burnham, Stephen G. Jenkins, Eileen M. Burd, Lars F. Westblade

Open Access Publications

No abstract provided.


L-Wrn Conditioned Medium For Gastrointestinal Epithelial Stem Cell Culture Shows Replicable Batch-To-Batch Activity Levels Across Multiple Research Teams, Kelli L. Vandussen, Naomi M. Sonnek, Thaddeus S. Stappenbeck Jan 2019

L-Wrn Conditioned Medium For Gastrointestinal Epithelial Stem Cell Culture Shows Replicable Batch-To-Batch Activity Levels Across Multiple Research Teams, Kelli L. Vandussen, Naomi M. Sonnek, Thaddeus S. Stappenbeck

Open Access Publications

No abstract provided.


Enhanced Delivery Of Oncolytic Adenovirus By Neural Stem Cells For Treatment Of Metastatic Ovarian Cancer, Rachael Mooney, Asma Abdul Majid, Jennifer Batalla-Covello, Diana Machado, Xueli Liu, Joanna Gonzaga, Revathiswari Tirughana, Mohamed Hammad, Thanh H. Dellinger, Maciej S. Lesniak, David T. Curiel, Karen S. Aboody Jan 2019

Enhanced Delivery Of Oncolytic Adenovirus By Neural Stem Cells For Treatment Of Metastatic Ovarian Cancer, Rachael Mooney, Asma Abdul Majid, Jennifer Batalla-Covello, Diana Machado, Xueli Liu, Joanna Gonzaga, Revathiswari Tirughana, Mohamed Hammad, Thanh H. Dellinger, Maciej S. Lesniak, David T. Curiel, Karen S. Aboody

Open Access Publications

No abstract provided.


Pancreatic Stone Protein/ Regenerating Protein Is A Potential Biomarker For Endoplasmic Reticulum Stress In Beta Cells, Stephen Stone, Damien Abreu, Jana Mahadevan, Rie Asada, Kelly Kries, Rolf Graf, Bess A. Marshall, Tamara Hershey, Fumihiko Urano Jan 2019

Pancreatic Stone Protein/ Regenerating Protein Is A Potential Biomarker For Endoplasmic Reticulum Stress In Beta Cells, Stephen Stone, Damien Abreu, Jana Mahadevan, Rie Asada, Kelly Kries, Rolf Graf, Bess A. Marshall, Tamara Hershey, Fumihiko Urano

Open Access Publications

No abstract provided.


P5rhh Nanoparticle-Mediated Delivery Of Axl Sirna Inhibits Metastasis Of Ovarian And Uterine Cancer Cells In Mouse Xenografts, Kathryn A. Mills, Jeanne M. Quinn, S. Tanner Roach, Marguerite Palisoul, Mai Nguyen, Hollie Noia, Lei Guo, Jawad Fazal, David G. Mutch, Samuel A. Wickline, Hua Pan, Katherine C. Fuh Jan 2019

P5rhh Nanoparticle-Mediated Delivery Of Axl Sirna Inhibits Metastasis Of Ovarian And Uterine Cancer Cells In Mouse Xenografts, Kathryn A. Mills, Jeanne M. Quinn, S. Tanner Roach, Marguerite Palisoul, Mai Nguyen, Hollie Noia, Lei Guo, Jawad Fazal, David G. Mutch, Samuel A. Wickline, Hua Pan, Katherine C. Fuh

Open Access Publications

No abstract provided.


Evidence For Altered Neurodevelopment And Neurodegeneration In Wolfram Syndrome Using Longitudinal Morphometry, Heather M. Lugar, Jonathan M. Koller, Jerrel Rutlin, Sarah A. Eisenstein, Olga Neyman, Anagha Narayanan, Ling Chen, Joshua S. Shimony, Tamara Hershey Jan 2019

Evidence For Altered Neurodevelopment And Neurodegeneration In Wolfram Syndrome Using Longitudinal Morphometry, Heather M. Lugar, Jonathan M. Koller, Jerrel Rutlin, Sarah A. Eisenstein, Olga Neyman, Anagha Narayanan, Ling Chen, Joshua S. Shimony, Tamara Hershey

Open Access Publications

No abstract provided.


Genome Organization Of Canada Goose Coronavirus, A Novel Species Identified In A Mass Die-Off Of Canada Geese, Amber Papineau, Yohannes Berhane, Todd N. Wylie, Kristine M. Wylie, Samuel Sharpe, Oliver Lung Jan 2019

Genome Organization Of Canada Goose Coronavirus, A Novel Species Identified In A Mass Die-Off Of Canada Geese, Amber Papineau, Yohannes Berhane, Todd N. Wylie, Kristine M. Wylie, Samuel Sharpe, Oliver Lung

Open Access Publications

No abstract provided.


Hepatic Arginase 2 (Arg2) Is Sufficient To Convey The Therapeutic Metabolic Effects Of Fasting, Yiming Zhang, Cassandra B. Higgins, Hannah M. Fortune, Phillip Chen, Alicyn I. Stothard, Allyson L. Mayer, Benjamin M. Swarts, Brian J. Debosch Jan 2019

Hepatic Arginase 2 (Arg2) Is Sufficient To Convey The Therapeutic Metabolic Effects Of Fasting, Yiming Zhang, Cassandra B. Higgins, Hannah M. Fortune, Phillip Chen, Alicyn I. Stothard, Allyson L. Mayer, Benjamin M. Swarts, Brian J. Debosch

Open Access Publications

No abstract provided.


The Bin1 Rs744373 Snp Is Associated With Increased Tau-Pet Levels And Impaired Memory, N Franzmeier, A Rubinski, J Neitzel, M Ewers, John Morris, Marcus Raichle, David Holtzman, Nigel J. Cairns, Erin Householder, Lisa Taylor-Reinwald, Beau Ances, Maria Carroll, Sue Leon, Mark A. Mintun, Stacy Schneider, Angela Oliver Jan 2019

The Bin1 Rs744373 Snp Is Associated With Increased Tau-Pet Levels And Impaired Memory, N Franzmeier, A Rubinski, J Neitzel, M Ewers, John Morris, Marcus Raichle, David Holtzman, Nigel J. Cairns, Erin Householder, Lisa Taylor-Reinwald, Beau Ances, Maria Carroll, Sue Leon, Mark A. Mintun, Stacy Schneider, Angela Oliver

Open Access Publications

No abstract provided.


Prediction Of Functional Microrna Targets By Integrative Modeling Of Microrna Binding And Target Expression Data, Weijun Liu, Xiaowei Wang Jan 2019

Prediction Of Functional Microrna Targets By Integrative Modeling Of Microrna Binding And Target Expression Data, Weijun Liu, Xiaowei Wang

Open Access Publications

No abstract provided.


Repetitive Concussive And Subconcussive Injury In A Human Tau Mouse Model Results In Chronic Cognitive Dysfunction And Disruption Of White Matter Tracts, But Not Tau Pathology, Mihika Gangolli, Joseph Benetatos, Thomas J. Esparza, Emeka M. Fountain, Shamilka Seneviratne, David L. Brody Jan 2019

Repetitive Concussive And Subconcussive Injury In A Human Tau Mouse Model Results In Chronic Cognitive Dysfunction And Disruption Of White Matter Tracts, But Not Tau Pathology, Mihika Gangolli, Joseph Benetatos, Thomas J. Esparza, Emeka M. Fountain, Shamilka Seneviratne, David L. Brody

Open Access Publications

No abstract provided.


Defining A Murine Ovarian Cancer Model For The Evaluation Of Conditionally-Replicative Adenovirus (Crad) Virotherapy Agents, Rebeca Gonzalez-Pastor, Ahmad Mohammad Ashshi, Adel Galal El-Shemi, Igor P. Dmitriev, Elena A. Kashentseva, Zhi Hong Lu, S. Peter Goedegebuure, Osvaldo L. Podhajcer, David T. Curiel Jan 2019

Defining A Murine Ovarian Cancer Model For The Evaluation Of Conditionally-Replicative Adenovirus (Crad) Virotherapy Agents, Rebeca Gonzalez-Pastor, Ahmad Mohammad Ashshi, Adel Galal El-Shemi, Igor P. Dmitriev, Elena A. Kashentseva, Zhi Hong Lu, S. Peter Goedegebuure, Osvaldo L. Podhajcer, David T. Curiel

Open Access Publications

No abstract provided.


Repetitive Transcranial Magnetic Stimulation With Resting-State Network Targeting For Treatment-Resistant Depression In Traumatic Brain Injury: A Randomized, Controlled, Double-Blinded Pilot Study, Shan H. Siddiqi, Nicholas T. Trapp, Carl D. Hacker, Timothy O. Laumann, Sridhar Kandala, Xin Hong, Ludwig Trillo, Pashtun Shahim, Eric C. Leuthardt, Alexandre R. Carter, David L. Brody Jan 2019

Repetitive Transcranial Magnetic Stimulation With Resting-State Network Targeting For Treatment-Resistant Depression In Traumatic Brain Injury: A Randomized, Controlled, Double-Blinded Pilot Study, Shan H. Siddiqi, Nicholas T. Trapp, Carl D. Hacker, Timothy O. Laumann, Sridhar Kandala, Xin Hong, Ludwig Trillo, Pashtun Shahim, Eric C. Leuthardt, Alexandre R. Carter, David L. Brody

Open Access Publications

No abstract provided.


Fatty Acid Oxidation Promotes Cardiomyocyte Proliferation Rate But Does Not Change Cardiomyocyte Number In Infant Mice, Tongtong Cao, Daniela Liccardo, Ryan Lacanna, Xiaoying Zhang, Rong Lu, Brian N. Finck, Tani Leigh, Xiongwen Chen, Konstantinos Drosatos, Ying Tian Jan 2019

Fatty Acid Oxidation Promotes Cardiomyocyte Proliferation Rate But Does Not Change Cardiomyocyte Number In Infant Mice, Tongtong Cao, Daniela Liccardo, Ryan Lacanna, Xiaoying Zhang, Rong Lu, Brian N. Finck, Tani Leigh, Xiongwen Chen, Konstantinos Drosatos, Ying Tian

Open Access Publications

No abstract provided.


The Macaque Cerebellar Flocculus Outputs A Forward Model Of Eye Movement, Gyutae Kim, Jean Laurens, Tatyana A. Yakusheva, Pablo M. Blazquez Jan 2019

The Macaque Cerebellar Flocculus Outputs A Forward Model Of Eye Movement, Gyutae Kim, Jean Laurens, Tatyana A. Yakusheva, Pablo M. Blazquez

Open Access Publications

No abstract provided.


The Lab Management Practices Of “Research Exemplars” That Foster Research Rigor And Regulatory Compliance: A Qualitative Study Of Successful Principal Investigators, Alison L. Antes, Ashley Kuykendall, James M. Dubois Jan 2019

The Lab Management Practices Of “Research Exemplars” That Foster Research Rigor And Regulatory Compliance: A Qualitative Study Of Successful Principal Investigators, Alison L. Antes, Ashley Kuykendall, James M. Dubois

Open Access Publications

No abstract provided.


Achieving Tight Control Of A Photoactivatable Cre Recombinase Gene Switch: New Design Strategies And Functional Characterization In Mammalian Cells And Rodent, Kyle Meador, Christina L. Wysoczynski, Aaron J. Norris, Jason Aoto, Michael R. Bruchas, Chandra L. Tucker Jan 2019

Achieving Tight Control Of A Photoactivatable Cre Recombinase Gene Switch: New Design Strategies And Functional Characterization In Mammalian Cells And Rodent, Kyle Meador, Christina L. Wysoczynski, Aaron J. Norris, Jason Aoto, Michael R. Bruchas, Chandra L. Tucker

Open Access Publications

No abstract provided.


Delineating And Validating Higher-Order Dimensions Of Psychopathology In The Adolescent Brain Cognitive Development (Abcd) Study, Giorgia Michelini, Deanna M. Barch, Yuan Tian, David Watson, Daniel N. Klein, Roman Kotov Jan 2019

Delineating And Validating Higher-Order Dimensions Of Psychopathology In The Adolescent Brain Cognitive Development (Abcd) Study, Giorgia Michelini, Deanna M. Barch, Yuan Tian, David Watson, Daniel N. Klein, Roman Kotov

Open Access Publications

No abstract provided.


Steady-State Activation Of The High-Affinity Isoform Of The Α4Β2Δ Gabaa Receptor, Spencer R. Pierce, Thomas C. Senneff, Allison L. Germann, Gustav Akk Jan 2019

Steady-State Activation Of The High-Affinity Isoform Of The Α4Β2Δ Gabaa Receptor, Spencer R. Pierce, Thomas C. Senneff, Allison L. Germann, Gustav Akk

Open Access Publications

No abstract provided.


Zbtb32 Restrains Antibody Responses To Murine Cytomegalovirus Infections, But Not Other Repetitive Challenges, Arijita Jash, You W. Zhou, Diana K. Gerardo, Tyler J. Ripperger, Bijal A. Parikh, Sytse Piersma, Deepa R. Jamwal, Pawel R. Kiela, Adrianus C. M. Boon, Wayne M. Yokoyama, Chyi S. Hsieh, Deepta Bhattacharya Jan 2019

Zbtb32 Restrains Antibody Responses To Murine Cytomegalovirus Infections, But Not Other Repetitive Challenges, Arijita Jash, You W. Zhou, Diana K. Gerardo, Tyler J. Ripperger, Bijal A. Parikh, Sytse Piersma, Deepa R. Jamwal, Pawel R. Kiela, Adrianus C. M. Boon, Wayne M. Yokoyama, Chyi S. Hsieh, Deepta Bhattacharya

Open Access Publications

No abstract provided.


Effect Of Native And Acetylated Dietary Resistant Starches On Intestinal Fermentative Capacity Of Normal And Stunted Children In Southern India, Ramadass Balamurugan, Srinivasan Pugazhendhi, Gowri M Balachander, Tamilselvan Dharmalingam, Elissa K Mortimer, Geetha L Gopalsamy, Richard J Woodman, Rosie Meng, David H Alpers, Mark Manary, Henry J Binder, Ian L Brown, Graeme P Young, Balakrishnan S Ramakrishna Jan 2019

Effect Of Native And Acetylated Dietary Resistant Starches On Intestinal Fermentative Capacity Of Normal And Stunted Children In Southern India, Ramadass Balamurugan, Srinivasan Pugazhendhi, Gowri M Balachander, Tamilselvan Dharmalingam, Elissa K Mortimer, Geetha L Gopalsamy, Richard J Woodman, Rosie Meng, David H Alpers, Mark Manary, Henry J Binder, Ian L Brown, Graeme P Young, Balakrishnan S Ramakrishna

Open Access Publications

The health benefits of dietary amylase resistant starch (RS) arise from intestinal microbial fermentation and generation of short chain fatty acids (SCFA). We compared the intestinal fermentative capability of stunted and nonstunted ('healthy') children in southern India using two types of RS: high amylose maize starch (HAMS) and acetylated HAMS (HAMSA). Twenty children (10 stunted and 10 healthy) aged 2 to 5 years were fed biscuits containing HAMS (10 g/day) for two weeks followed by a 2-week washout and then HAMSA biscuits (10 g/day) for 2 weeks. Fecal samples were collected at 3-4 day intervals and pH and SCFA analyzed. …


Transdermal Fluorescence Detection Of A Dual Fluorophore System For Noninvasive Point-Of-Care Gastrointestinal Permeability Measurement, Richard B Dorshow, J R Johnson, Martin P Debreczeny, I Rochelle Riley, Jeng-Jong Shieh, Thomas E Rogers, Carla Hall-Moore, Nurmohammad Shaikh, L Colleen Rouggly-Nickless, Phillip I Tarr Jan 2019

Transdermal Fluorescence Detection Of A Dual Fluorophore System For Noninvasive Point-Of-Care Gastrointestinal Permeability Measurement, Richard B Dorshow, J R Johnson, Martin P Debreczeny, I Rochelle Riley, Jeng-Jong Shieh, Thomas E Rogers, Carla Hall-Moore, Nurmohammad Shaikh, L Colleen Rouggly-Nickless, Phillip I Tarr

Open Access Publications

The intestinal mucosal barrier prevents macromolecules and pathogens from entering the circulatory stream. Tight junctions in this barrier are compromised in inflammatory bowel diseases, environmental enteropathy, and enteric dysfunction. Dual sugar absorption tests are a standard method for measuring gastrointestinal integrity, however, these are not clinically amenable. Herein, we report on a dual fluorophore system and fluorescence detection instrumentation for which gastrointestinal permeability is determined in a rat small bowel disease model from the longitudinal measured transdermal fluorescence of each fluorophore. This fluorophore technology enables a specimen-free, noninvasive, point-of-care gastrointestinal permeability measurement which should be translatable to human clinical studies.


Mechanism Of Microtubule Plus-End Tracking By The Plant-Specific Spr1 Protein And Its Development As A Versatile Plus-End Marker, Rachappa Balkunde, Layla Foroughi, Eric Ewan, Ryan Emenecker, Valeria Cavalli, Ram Dixit Jan 2019

Mechanism Of Microtubule Plus-End Tracking By The Plant-Specific Spr1 Protein And Its Development As A Versatile Plus-End Marker, Rachappa Balkunde, Layla Foroughi, Eric Ewan, Ryan Emenecker, Valeria Cavalli, Ram Dixit

Open Access Publications

No abstract provided.


Myeloid Acat1/Soat1 Ko Attenuates Pro-Inflammatory Responses In Macrophages And Protects Against Atherosclerosis In A Model Of Advanced Lesions, Elaina M. Melton, Haibo Li, Jalen Benson, Paul Sohn, Li-Hao Huang, Bao-Liang Song, Bo-Liang Li, Catherine C.Y. Chang, Ta-Yuan Chang Jan 2019

Myeloid Acat1/Soat1 Ko Attenuates Pro-Inflammatory Responses In Macrophages And Protects Against Atherosclerosis In A Model Of Advanced Lesions, Elaina M. Melton, Haibo Li, Jalen Benson, Paul Sohn, Li-Hao Huang, Bao-Liang Song, Bo-Liang Li, Catherine C.Y. Chang, Ta-Yuan Chang

Open Access Publications

No abstract provided.


Phosphorylation Of The Hcn Channel Auxiliary Subunit Trip8b Is Altered In An Animal Model Of Temporal Lobe Epilepsy And Modulates Channel Function, Kendall M. Foote, Kyle A. Lyman, Ye Han, Ioannis E. Michailidis, Robert J. Heuermann, Danielle Mandikian, James S. Trimmer, Geoffrey T. Swanson, Dane M. Chetkovich Jan 2019

Phosphorylation Of The Hcn Channel Auxiliary Subunit Trip8b Is Altered In An Animal Model Of Temporal Lobe Epilepsy And Modulates Channel Function, Kendall M. Foote, Kyle A. Lyman, Ye Han, Ioannis E. Michailidis, Robert J. Heuermann, Danielle Mandikian, James S. Trimmer, Geoffrey T. Swanson, Dane M. Chetkovich

Open Access Publications

No abstract provided.


Developmental Pathology Of Congenital Kidney And Urinary Tract Anomalies, Sanjay Jain, Feng Chen Jan 2019

Developmental Pathology Of Congenital Kidney And Urinary Tract Anomalies, Sanjay Jain, Feng Chen

Open Access Publications

No abstract provided.


Test–Retest Performance Of A 1-Hour Multiparametric Mr Image Acquisition Pipeline With Orthotopic Triple-Negative Breast Cancer Patient-Derived Tumor Xenografts, Xia Ge, James D. Quirk, John A. Engelbach, G. Larry Bretthorst, Shunqiang Li, Kooresh I. Shoghi, Joel R. Garbow, Joseph J.H. Ackerman Jan 2019

Test–Retest Performance Of A 1-Hour Multiparametric Mr Image Acquisition Pipeline With Orthotopic Triple-Negative Breast Cancer Patient-Derived Tumor Xenografts, Xia Ge, James D. Quirk, John A. Engelbach, G. Larry Bretthorst, Shunqiang Li, Kooresh I. Shoghi, Joel R. Garbow, Joseph J.H. Ackerman

Open Access Publications

No abstract provided.


Npy2r Signaling Gates Spontaneous And Mechanical, But Not Thermal, Pain Transmission, Sihan Chen, Xian-Yu Liu, Yingfu Jiao, Zhou-Feng Chen, Weifeng Yu Jan 2019

Npy2r Signaling Gates Spontaneous And Mechanical, But Not Thermal, Pain Transmission, Sihan Chen, Xian-Yu Liu, Yingfu Jiao, Zhou-Feng Chen, Weifeng Yu

Open Access Publications

No abstract provided.


Microglia Drive Apoe-Dependent Neurodegeneration In A Tauopathy Mouse Model, Yang Shi, Melissa Manis, Justin Long, Kairuo Wang, Patrick M. Sullivan, Javier Remolina Serrano, Rosa Hoyle, David M. Holtzman Jan 2019

Microglia Drive Apoe-Dependent Neurodegeneration In A Tauopathy Mouse Model, Yang Shi, Melissa Manis, Justin Long, Kairuo Wang, Patrick M. Sullivan, Javier Remolina Serrano, Rosa Hoyle, David M. Holtzman

Open Access Publications

No abstract provided.


Neutralizing Antibodies Against Mayaro Virus Require Fc Effector Functions For Protective Activity, James T. Earnest, Katherine Basore, Vicky Roy, Adam L. Bailey, David Wang, Galit Alter, Daved H. Fremont, Michael S. Diamond Jan 2019

Neutralizing Antibodies Against Mayaro Virus Require Fc Effector Functions For Protective Activity, James T. Earnest, Katherine Basore, Vicky Roy, Adam L. Bailey, David Wang, Galit Alter, Daved H. Fremont, Michael S. Diamond

Open Access Publications

No abstract provided.