Digital Commons Network^™

Characterization Of P38alpha And Nitric Oxide Synthase 3 Binding, Gillyan M. Jewett

Master's Theses

P38alpha is a member of the mitogen activated protein kinase (MAPK) family. This family is important for mediating signal transduction pathways through phosphorylation of downstream substrates. Previous work has described the ability of p38alpha to bind and phosphorylate nitric oxide synthase 3 (NOS3) at two sites, the autoinhibitory loop (AI) at S600 and the N-terminal MAPK binding site (NtMAP) at S114. P38alpha has two substrate binding domains, the common docking groove (CD-groove) and a hydrophobic pocket (DEF) that are important in binding and phosphorylating various substrates specific to each pocket. Utilizing biolayer interferometry, this work describes the importance of both …

The Doctrine Of The Trinity In Southern African Seventh-Day Adventism: A Historical-Theological Study, 1887-1974, Grant Lottering

Master's Theses

The Topic

The doctrine of the Trinity in the history of the Seventh-day Adventist Church has often been viewed with suspicion, largely because many early Adventist pioneers expressed seemingly anti-Trinitarian sentiments. However, a review of Seventh-day Adventist publications reveals that early Adventists actually rejected Modalism, a misunderstood variation of Trinitarianism, rather than the biblical concept of the Trinity. When Seventh-day Adventist missionaries arrived in Africa in 1887, the earliest converts had a Dutch Reformed background and were already Trinitarian. Seventh-day Adventists found that their understanding of the Trinity aligned with these converts’ beliefs, and thus, they never needed to correct …

The Divine Call: Theophanies Of Athena And Yhwh In Comparative Perspective, Kenny Gomes Ebinger

Master's Theses

Problem

While parallels between Ancient Near East (ANE) literature and the Hebrew Bible are well established in contemporaneous scholarship, the Greek corpus has received little attention in recent studies. This paper addresses this gap by investigating a theophany scene from each corpus, in order to compare how the human-deity encounter is presented in Exodus 3:1–4:17 and Odyssey 1:96–324.

Method

The textual analysis of each scene employs a narratological framework. It takes both texts synchronically and grounds its comparison on the narrative formal elements, structures, and functions. The similarities and differences between each theophany are presented by their emerging themes and …

Coding The Greek New Testament In The Text-Fabric Open Source Environment, Saulo De Oliveira Cantanhêde

Master's Theses

Problem

Over the centuries, the Bible has been reproduced in various forms, from scrolls to codex, handwritten codex to printed books, and, more recently, the digital Bible. However, proprietary software tools lack in providing a more rigorous approach to advanced research in data-driven linguistic and exegetical studies.

Method

I report the final implementation of a data conversion project to convert an existing open source Nestle 1904 Greek New Testament encoded in XML format through Text-Fabric software (N1904-TF). The data was converted using Python packages and made available in a GitHub repository for programmers and non-programmers. Also, I developed over 60 …

A Comparative Analysis Of Current Understandings Of The High Priestly Ministry Of Jesus In The Heavenly Sanctuary, Samuel Amirtharaj

Master's Theses

Problem

Seventh-day Adventists consider the subject of the sanctuary to be the kingpin that interconnects all of the other doctrines. Both Adventists and non-Adventists agree that it is the Adventist understanding of the sanctuary that sets them apart from other Christian denominations. Almost since the inception of the Church, there have been many critics of the Adventist doctrine of the sanctuary and its associated teachings, both from within and from without the Church. Former Adventists and non-Adventists alike have discredited the significance of the sanctuary. However, numerous books on the sanctuary have been published recently by Christian scholars; these books …

The State Of Man In Romans 7:22-25: Historical And Exegetical Approaches, J Daniel Miranda

Master's Theses

Problem

This thesis addresses the question as to the identity of “I” in Romans 7 and the related spiritual experience. Romans 7 is a very complex chapter that has elicited multiple discussions, which still do not answer the theological problems satisfactorily. Such theological pluralism has also led to various views regarding sin and salvation. Since understanding sin and redemption are fundamental to one’s salvation, there are strong feelings related to the different positions taken. This has also been the case in Adventism, and, unfortunately, this has affected the unity of the church. Part of the problem is seeing the regenerate-unregenerate …

Genetic Influences On Individual Variability In Western Lowland Gorilla (Gorilla Gorilla Gorilla) Social Behavior, Hadley Mueller-Hill

Master's Theses

While primates are considered highly social animals, the evolutionary origins and mechanisms underlying their social behaviors remain unclear. Not only do they exhibit an extensive range of behaviors, but individuals within the same species can also vary widely in their social interactions. Genetics play a significant role in shaping these individual variations in behavior; multiple genetic variants have been associated with differences in social behavior in mammals. Examples of these include MAOA and OXTR genes, which influence the expression of behaviors associated with antisocial and prosocial temperaments. Genetic polymorphisms affect primate interactions, impacting an individual’s ability to maintain its status …

Scans, Carlos D. Leon

Master's Theses

scans is a collection of poems that explore my memories within the small farm town of Soledad, California. This collection examines the intersections of religious experiences, relationships, and core regional identifiers. I believe literature transcends time and works as a capsule for our experiences. This collection looks to examine and elevate the qualities of these experiences, inviting the reader to rediscover their own memories and the minor details lost within them. Separated into four sections, each poem works as a fragmented memory, with the intent of creating a near, complete image of their designated section. I seek to provide an …

Stream Response To A Dam Removal: Mill Creek, Davenport, Ca, Jessica J. Williamson

Master's Theses

Dams have many effects on stream morphology and ecology, including a loss of sediment supply downstream, reduced access to the entire stream for aquatic fauna, and a flooded area upstream of the dam. Dams are a hurdle for migrating organisms such as anadromous fish, which is a group of concern. An over 100-year-old dam on Mill Creek, a stream draining a coastal watershed in central California, was removed in the fall of 2021. The site is in the Santa Cruz Mountains, where endangered salmonids such as steelhead, Oncorhynchus mykiss, have historically lived. To study the change in the stream from …

Separation And Surface Examination Of Spacecraft Cabin Particulates, Grace A. Belancik

Master's Theses

Particulate matter in the atmosphere is a known detriment to human health, but several factors affect any particulate’s particular toxicity including particle size, surface area, and chemical composition. Extensive studies have been conducted to examine particulate hazards on Earth, but in crewed spacecraft, like the International Space Station (ISS), the particulate environment is wholly unique due to both the controlled environment and lack of gravity. Atmospheric sampling studies are underway, but another convenient source of airborne particulates for analysis is the contents of the vacuum bags used by the astronauts to clean the air vents. However, no method currently exists …

Ml Model To Better Identify Instances Of Bullying Faced By Members Of The Lgbtq+ Community, Arslan Bisharat

Master's Theses

Cyberbullying poses a significant threat to online communities, with the LGBTQ+ community facing disproportionately higher rates of harassment. While existing cyberbullying detection systems have made progress in identifying general instances of online harassment, they often fail to capture the nuanced and context-dependent nature of LGBTQ+-targeted bullying. This thesis presents a novel approach to this challenge by developing SpectrumNet, an LGBTQ+-centric transformer-based model for cyberbullying detection. Our research was conducted in two phases. In Phase 1, we evaluated the effectiveness of pre-trained transformer models (RoBERTa, BERT, and GPT-2) in identifying LGBTQ+-related cyberbullying. Building on these findings, Phase 2 introduced SpectrumNet which …

Endocrine Responses To Two Distinct Foraging Contexts In The Bonobo (Pan Paniscus), Lauren Mitchell

Master's Theses

In gregarious animals, a social structure characterized by female dominance is relatively rare. However, bonobos (Pan paniscus), one of the two species most closely related to humans, are characterized by partial female dominance, with females forming close social bonds. In contrast, chimpanzees (Pan troglodytes), a close relative of the bonobo, are characterized by strong male-male bonding and social dominance with female chimpanzees lacking close social bonds. There is a lack of consensus concerning the reasons for these behavioral differences in Pan, specifically, the physiological processes responsible for female dominance in bonobos. The role of hormones …

Fault Box Modeling Of Dip Slip Faults: A Framework For Fault Box Design And Future Studies, Hailey Pressnell

Master's Theses

The behavior of soils during surface fault rupture is a serious concern in the planning and design of infrastructure that may be located within or near a fault zone. Challenges associated with developing mitigation measures for surface fault rupture include the uncertainty of fault rupture and the variability of fault behavior. Current analytical procedures define surface fault rupture according to the type of fault movement (strike slip, normal or reverse), the amount of displacement on the fault, and the mechanics of the material overlying the fault. The purpose of this thesis is to reconfirm analytical solutions and gain a better …

Analyzing The Safety Effects Of Edge Lane Roads For Motor Vehicle Users, John Yang

Master's Theses

This thesis builds upon a prior study that analyzed the safety effects of Edge Lane Roads (ELRs) within the U.S. context, addressing gaps related to collision, traffic volume, and speed data. An ELR is a roadway configuration that accommodates two-way automobile traffic within a single center lane while providing edge lanes for vulnerable road users (VRUs), i.e., bicyclists or pedestrians. Although the concept of a single shared lane for opposing traffic often raises safety concerns among the public, ELRs have demonstrated potential to control speeds, optimize roadway space, and improve traffic operations on low-volume roads.

To evaluate safety outcomes, this …

The Radical Oxidation Of Hydroxyacetone: An Insight Into The Reaction Mechanism And Potential Tetraoxide Intermediates, Edward Buck

Master's Theses

This thesis presents the reaction of hydroxyacetone, a common volatile organic compound (VOC), with chlorine radicals in the presence of oxygen. Chapter one explores VOCs and their specific reactions and how tetraoxide intermediates could be formed from them. Chapter two analyses the experimental and computational methods used and the key theoretical concepts behind these methods. Experimental data was collected using multiplexed photoionization mass spectrometry at the Advanced Light Source Chemical Transformations Beamline, Lawrence Berkeley National laboratory. This data is combined with theoretical data using the CBS-QB3 composite method to determine the key reaction intermediates and mechanisms.

The main chapter of …

Indigenous Metal: Rage, Rejects, And The Reconstruction Of Culture, Louis W. Asbury

Master's Theses

Metal music’s latest frontier is Indigenous metal, combining explorations of Indigenous identity with the heavy and aggressive stylings of the music genre. To explore this new subgenre, this study asks to what extent can metal music be used as a political tool and what are some of the broader effects of metal bands working to better their communities. This thesis utilizes case studies of two notable Indigenous metal scenes, the Rez metal scene in the Navajo Nation and the Māori metal scene in Aotearoa. By collecting data from these scenes, including lyrics, videos, interviews, and audience interactions, this thesis thoroughly …

សត្វកង្ហែនប្រាជ្ញានិងសត្វចាបពូកនិយាយ : The Wise Treeshrew And A Talking Sparrow, Jacob Liechty

Master's Theses

រួមដើរជាមួយ ច័ន្ទត្រា វុធ្ទ វាសនា និងចេក្ខាប់ ក្នុងបេលយើងធ្វើដំណើរទៅស្រុកថៃ លើក ទី២ ទី២ ទី១០០ និង ទី១។ ជួបបងប្អូនខ្មែរនិងជនកម្ពុជា ក្នុងចំនួនមួយលានដែលរស់នៅក្នុងថៃ នៅចំការនិងក្រុង គង់នៅដោយផ្លាស់ពីកន្លែងថ្លៃខ្ពស់និងធ្វើការខ្លាំងគ្រោះ។ រៀនពីប៉ាវុធ្ទ រៀងប្រវត្តិលំបាក មកពីសម័យទាហានអាមេរិកចូលនិងទម្លាក់គ្រាប់បែក និងសង្គ្រាមគ្នាឯង និងការភៀសខ្លួន និងការបាត់បង់ផ្ទះទឹកដីក្នុងស្រុកខ្មែរ។ សង្ឈឹមអំពីអនាគត ដោយរកឃើញចិត្តសាសនា ពិនិត្យកំហុសខ្ញុំ និងយល់ឫសឡើងវេញ៕

Join Chandra, Voth, Viasna, and Jacob in Cambodia as we travel to Thailand for the second, second, hundredth, and first time. Meet Khmer and Cambodian brethren, out of the million living in Thai farms and cities, surviving via costly migration and precarious labor. Learn, from Pa Voth, a challenging history spanning back to the United States occupation and bombing, through civil war and refugee crises, and the loss of home and environment for Cambodians …

Connecting Through Screens: A Case Study On Student Engagement In Online Esol Classes In The Post Pandemic Era, Meral Kacar

Master's Theses

The sudden shift to emergency online education during the global pandemic affected various academic fields, including English language teaching. While many schools faced challenges, some successfully implemented online educational programs. Despite the large impact of the global pandemic on education, there is limited research that examines the effectiveness of online ESOL programs with a focus on the key factors that contribute to student engagement. This thesis explores the factors contributing to effective online ESOL instruction, focusing on fostering engagement and improving teaching practices in the post-pandemic era. The study for this thesis employs an instrumental case study methodology, focusing on …

Decolonial Possibilities For Non-Indigenous Environmental Educators, Emeric Bisbee

Master's Theses

Non-Indigenous environmental educators must incorporate Indigenous knowledges and worldviews to successfully teach about contemporary environmental problems such as sustainability. However, there are several barriers for non-Indigenous environmental educators to incorporate Indigenous knowledges, such as (a) Western science as the primary epistemology of environmental education, delegitimizing Indigenous ways of knowing, (b) non-Indigenous peoples’ reliance on the privileges gained by settler colonialism which works to erase and replace Indigenous peoples and knowledges, and (c) the historical and current injustices experienced by Indigenous peoples in schools because of settler colonialism. This study explored how experienced non-Indigenous environmental educators who incorporate Indigenous knowledges and …

Closed Domain Question Answering With Language Models: Application Of Retrieval-Augmented Generation And Parameter Efficient Fine-Tuning In Healthcare, Aaron Cummings

Master's Theses

Dementia care presents significant challenges for informal caregivers, particularly in managing behavioral symptoms that affect over 90% of individuals with Alzheimer’s Disease and Related Dementias (ADRD) during the moderate-to-severe stages. These symptoms, including agitation, wandering, and repetitive activities, impose emotional and physical burdens on caregivers, often exacerbated by a lack of reliable, accessible, and personalized resources. Non-pharmacological interventions, while evidence-based, are underutilized due to knowledge gaps and the inefficiency of traditional training and information retrieval methods.

This research explores the adaptation of large language models (LLMs) to address these challenges by developing a framework for closed-domain Question Answering (QA) systems, …

Design, Synthesis, And Nmr-Guided Characterization Of A Targeted Covalent Inhibitor-Like Molecule Against Ivyp1 From P. Aeruginosa, Samuel Taylor Moore

Master's Theses

Multi-drug resistance poses a serious threat to future generations and historical antibiotic pipelines; consequently, the medical and economic burdens associated with treating multidrug-resistant bacteria are substantiated. In this context, P. aeruginosa (PA) emerges as one of the most significant healthcare challenges, being a leading cause of resistance-associated mortality worldwide. Despite modern efforts to combat these poor outcomes, drug-resistant cases continue to rise, and the need for novel antibiotic treatment is apparent. To this end, we investigated relevant resistance mechanisms and past antibiotic targets within PA, and in doing so, we identified relationships between peptidoglycan biology and a periplasmic protein, Inhibitor …

Real-Time Feedback-Driven Framework For Automated Cybersickness Mitigation, Md Jahirul Islam

Master's Theses

As technologies are becoming more advanced day by day, the embracement of virtual reality (VR) technology among users is also increasing in daily activities for various purposes, and subsequently, the barrier between the real and virtual world is fading. Despite the versatile uses, cybersickness (CS) is a major problem which is induced among users due to the immersive VR experience. There is a plethora of research findings and methods to measure the users’ CS such as virtual reality sickness questionnaire (VRSQ), simulator sickness questionnaire (SSQ), fast motion scale questionnaire (FMS), and others. Recently, machine learning approaches have also been adopted …

Reframing And Reclaiming Poetry In The Esl Classroom, Rebecca C. Eagleson

Master's Theses

The debate over using poetry as an authentic text in the ESOL classroom has persisted for nearly a century. However, emerging research from an EFL context suggests that reconsidering poetry in the ESL classroom may be timely. This literature review examines the origins of the controversy by highlighting the intersections of linguistics and literary criticism and how they shaped current ESOL approaches to poetry. It then outlines the standard points and counterpoints of the ESOL controversy over poetry. Finally, it evaluates recent case studies and methodological reviews from EFL contexts that have reignited new interest and research into utilizing poetry …

Measuring Gait Of Total Knee Arthroplasty Patients Pre-Op And Post-Op Using A Smartphone, Celeste A. Thai

Master's Theses

Motion capture technology is a tool often used in orthopedic applications, including measuring gait dysfunctions. However, gait analysis research focused on total knee arthroplasty (TKA) patients is limited, especially using motion capture systems. This may be due to a multitude of factors, such as inaccessibility to gait labs to the general public, difficulty of travel post-surgery, and overall costs of care and maintenance of motion lab equipment. New emerging novel methods use wearable devices such as smartphones and inertial measurement devices (IMUs) to perform gait assessment and are becoming favorable due to their increasingly ubiquitous nature. One such method using …

Soldiers In The Sideshows: The 409th Infantry Regiment In World War Ii, Nicholas Garrett

Master's Theses

In the European Theater of World War II certain battlefields or campaigns such as Operation Overlord, Operation Market Garden, and the Battle of the Bulge are core aspects of American memory. However, the men of the 409^th Infantry Regiment of the 103^rd Infantry Division do not fall into this image. This unit fought as part of the U.S. Seventh Army across eastern France through the Vosges Mountains, defended against the German Operation Nordwind and broke through the Siegfried Line into southeastern Germany. Though the 409^th represents a small portion of the men of the 103^rd, …

Just Deserts: The Moral Foundations Of Antagonistic Personality In Social Aggression, Summer Steely

Master's Theses

Social aggression is associated with adverse psychosocial consequences such as anxiety, depression, isolation, reciprocal violence, and suicidality (Zhu et al., 2024). Psychopathic personality traits and moral deficits have been linked to antisocial behavior, including social aggression; however, the role of moral value systems and trait moral disengagement in the context of social aggression is less clear. A more granular analysis of their utility may illuminate new pathways toward intervention. To advance this goal, the present study explored the relationships between the values of Moral Foundations Theory and social aggression among college students (N = 301). Two moral foundations (i.e., care …

Host Response To Implantation Of A Poly N-Isopropylarylamide Injectable Cell Therapy Vehicle, Cole Matthew Burk

Master's Theses

There is a need to develop novel and effective therapies targeting end-stage peripheral arterial occlusive disease (PAOD). Inducing collateral arteriogenesis is a possible novel treatment that produces a natural bypass for blood flow, a promising solution to the long-term issues seen with current treatments. Regenerative therapies, and progenitor cells specifically, have demonstrated great promise in repair after injury and disease. While most progenitor or stem cells have poor efficacy in this context, muscle progenitor cells, or myoblasts, have encouraging results. Myoblasts enhance arteriogenesis and secrete cytokines or chemokines that recruit monocytes to injury sites. Implanting these adherent cells in a …

Design And Testing Of A Prototype Prosthesis For Pediatric Upper-Limb Transradial Amputees To Provide Adjustable Size And Modular Characteristics, Paul Heli

Master's Theses

This study was conducted to develop a financially accessible body-powered upper-limb prosthetic socket that can be adjusted to maintain fit and function for a growing child with a transradial amputation. The main objectives of the study were to design, manufacture, and test a device that was comfortable, functional, affordable, and adjustable. The socket was designed to be comfortable using global variables controlling the computer-aided design (CAD) model size with user-specific measurements. Comfort was also incorporated using shape-forming of the socket for specific residual limb features. The device was designed to perform the two main functions of suspension, or attachment to …

Development Of A Pressure Sensing System Coupled With Deployable Machine Learning Models For Assessing Residual Limb Fit In Lower Limb Prosthetics, Maxwell D. Lewter

Master's Theses

Lower limb amputations pose significant challenges for patients, with over 150,000 cases annually in the U.S., leading to a high demand for effective prosthetics. However, only 43% of lower limb prosthetic users report satisfaction, primarily due to issues with socket fit, which is critical for comfort, stability, and preventing injury. This study presents a deployable sensing system for potentially real-time monitoring of prosthetic socket fit by using pressure sensors and convolutional neural networks (CNNs) to analyze the pressure distribution within the socket. A novel CNN architecture, utilizing both dilated and strided convolutions, is proposed to effectively capture spatial-temporal patterns in …

Thermal Modeling Of Cooling Time Of Submarine Dacite Lapilli Tuff: Brothers Volcano, Kermadec Arc, Kyler Byrd

Master's Theses

Little is known about submarine volcanoes' eruptive histories and styles, even though they are essential to developing island arc systems and represent the second largest volcanic systems on Earth. Scientific drilling allows for the opportunity to study these systems. This study focused on two drill sites on Brothers volcano from IODP Expedition 376: Site U1528, located on the resurgent cone, and Site U1530, located on the caldera rim. Expedition researchers analyzed samples for clast radius, density, thermal conductivity, and specific heat. This data was then entered into the heat transfer equation of a sphere to create a cooling curve model …