Digital Commons Network^™

Foucault's Pendulum, A Classical Analog For The Electron Spin State, Rebecca Linck

Master's Theses

Spin has long been regarded as a fundamentally quantum phenomena that is incapable of being described classically. To bridge the gap and show that aspects of spin's quantum nature can be described classically, this work uses a classical Lagrangian based on the coupled oscillations of Foucault's pendulum as an analog for the electron spin state in an external magnetic field. With this analog it is possible to demonstrate that Foucault's pendulum not only serves as a basis for explaining geometric phase, but is also a basis for reproducing a broad range of behavior from Zeeman-like frequency splitting to precession of …

The Effects Of Indoor Climbing Route Rating Manipulation On Participant Climbing Self-Efficacy, Phillip James Sandlin

Master's Theses

This quantitative study utilized a classical experiment design to explore the

effects of manipulation of indoor climbing route ratings on the climbing self-efficacy of 90 indoor rock climbers. Controversy surrounding the accuracy of the assigned ratings of indoor climbing routes is commonplace at indoor climbing facilities. For indoor rock climbers to accurately assess their abilities, set appropriate goals, and monitor their progress, they must be able to choose climbs that accurately represent their desired level of challenge. Statistical analysis of the data did not support a relationship between manipulation of climbing route ratings and any changes in participant climbing self-efficacy. …

Future Work Selves And Work-Related Outcomes: The Role Of Perceived Supervisor Support, Shama Arakeri

Master's Theses

The purpose of this study was to examine the relationships between future work selves and work-related outcomes such as proactive career behaviors, self-development organizational citizenship behaviors (OCBs), and work engagement. Future work self salience was used to capture employee work selves that could be easily and clearly recalled into memory. An additional purpose of the current study was to examine whether perceived supervisor support would moderate each of the three relationships. A total of 123 employees participated. Future work self salience was positively related to proactive career behaviors, self-development OCBs, and work engagement. Furthermore, perceived supervisor support was found to …

The Effect Of Dietary Methylmercury On Na+, K+, -Atpase Activity And Growth In Fall-Run Chinook Salmon (O. Tshawytscha), John Negrey

Master's Theses

Hatchery reared Chinook salmon from California's Central Valley were fed for 67 days (Apr-Jun, 2008) on fish pellets mixed with either 0, 1, 3, or 5 µg*g-1 methylmercury hydroxide. Weight, fork length, condition factor, and Na+,K+- ATPase measurements were determined every two weeks and a 96-h seawater challenge was conducted at the conclusion of the experiment.

Results from two-way ANOVA, with treatment and date as independent variables, indicated no significant differences for weight (F3, 32 = 1.38; P = 0.280), length (F3, 32 = 0.986; P = 0.412) and condition factor (F3, 32 = 0.239; P = 0.869). Post-hoc analysis …

Hydrogen/Deuterium Exchange Mass Spectrometry For The Study Of Methanol-Induced Conformational Transitions In Ubiquitin, Steven Raul Rocha

Master's Theses

In aqueous solutions with high concentrations of methanol at low pH, the global conformation of ubiquitin denatures to a structure of increased helical character at 50% methanol to a highly helical denatured structure at 90% methanol. Circular dichroism analysis and hydrogen/deuterium exchange mass spectrometry experiments have been reported for the monitoring of alcohol-induced conformational transitions of ubiquitin upon exposure to increasing concentrations of methanol. A bottom-up analysis of deuterium labeled ubiquitin was used in this study to examine the local conformational transitions of ubiquitin upon exposure to solutions of varying concentrations of methanol. Analysis of ubiquitin and nine peptide fragments, …

Behavior And Ecosystem Effects Of The Invasive Asian Clam (Corbicula Fluminea) In Urban Streams, Kayla Turek

Master's Theses

Invasive species can be detrimental to freshwater ecosystems. By completing laboratory and field studies to observe processes and behaviors of the invasive Asian Clam (Corbicula fluminea), I documented pathways whereby this invasive species impacts aquatic ecosystems under conditions typical of urbanized streams I found. The predominant pathways by which clams impacted nitrogen (N) cycling was through excretion thus increasing ammonium (NH4+) flux out of sediment and through bioturbation, which increased nitrate (NO3-) diffusion to the sediment and dinitrogen gas (N2) production (i.e., denitrification). The effect was greater under urban conditions, where C. fluminea population density and water column NO3- were …

Treading Identities: Second-Generation Christian Indian Americans Negotiating Race, Ethnicity And Religion In America, Soulit Chacko

Master's Theses

In this master's thesis, I examine the lives of young second generation Malayalee Christian Indian Americans. I focus on their religion, racial as well as their ethnic identities. My main findings centers on the thesis that my participants as brown Indians are dually marginalized not only because of their race as brown Indian Americans but also because of their presumed religious identity of being a Hindu. Drawing from detail interviews and participant observation with thirty young second generation Malayalee Christian Indian Americans, I find that my participants are struggling to frame their Christian identity in America. Participants described being racially …

Seeking Modernity, Brain Gain, And Brain Drain: The Historical Evolution Of Chinese Students' Overseas Education In The United States Since Modern China, Di Luo

Master's Theses

This thesis is an historical research project that examines major waves of Chinese students studying in the United States since the mid-nineteenth century, as well as the impact of returned, American-educated Chinese students to the modernization of Chinese society. It also discusses the trend and pattern of the current wave after 1978 and compare it with previous waves. The analysis and examination of this thesis is based on a wide variety of written documents in both Chinese and English, including historical literatures, academic articles, dissertations, surveys, government publications, statistical data from both primary and secondary sources, as well as educational …

Login To Learn: A Content Analysis Of Southeast Asian Policies On Technology And Education, Laura D. Pasley

Master's Theses

In the following thesis, using Aucoin's (2011) theoretical framework, I juxtapose the discourses neoliberalism and humanitarian "access" as they relate to describing the potential outcomes of ICT adoption in education. Through a content analysis, I sought to answer the research question: To what extent have the discourses of neoliberalism and "access" used in regional ASEAN policies influenced ICT policymaking at the national level of its member states? The findings demonstrated a slight difference between ICT policies published prior to the 2011 ASEAN policy, but those published "after" were all also published in 2011 which may point to forces outside of …

Supporting Minority Students Through Mentoring: Best Practices For Formal Mentoring Programs, Elizabeth Stockslager

Master's Theses

Approaches such as universal education, state and national standards, and reform acts have sought to ensure that all students in America receive the same level of education. However, education systems are limited by institutionalized racism. An analysis of the education system through the lens of Critical Race Theory highlights the need to look outside of the traditional school setting, while Culturally Relevant Pedagogy gives insights for understanding the best practices in meeting the needs of minority students. This research considers how mentoring provides support and success for minority students by working with students outside of the school structure. Using the …

The Effect Of Work-Related Programs On Dropout Rates: A Meta-Analysis, Jill Young

Master's Theses

One in four students drop out of school, which has long-lasting implications for the individual, employers, and society at large. Work-related programs, such as those that include career exploration or vocational training, are often employed by schools and communities to reduce school dropout rates. This thesis provides an update to a meta-analysis of experimental and quasi-experimental evaluations of dropout prevention programs conducted by Wilson, Tanner-Smith, Lipsey, Morrison, and Steinka-Frey in 2011, focusing on work-related dropout prevention programs. This study determined through meta-analysis of the logged odds-ratios that work-related programs have an odds-ratio of 1.66, indicating that work-related programs significantly reduce …

Alpha-Synuclein Aggregates Activate The Nlrp3 Inflammasome Following Vesicle Rupture, Rudy Orlando Cedillos

Master's Theses

Parkinson's disease (PD) and related synucleinopathies are progressive neurodegenerative disorders that feature the accumulation of intracellular inclusions known as Lewy bodies (LBs) in the brain. The presynaptic protein α-synuclein is the primary constituent of LBs and has been documented to play a major role in the pathogenesis of synucleinopathies. Recently, aggregated α-synuclein has been implicated in prompting microglia-mediated inflammation, a process associated with the progression of neuronal death in neurodegenerative disorders. Although the mechanisms surrounding the induction of neuroinflammation are not well understood, the recently discovered inflammasome-forming NLR proteins have emerged as regulators of inflammation. In this study, we sought …

Snail Induces Mesenchymal Transition And Promotes Egfr Tki Resistance In Nsclc Cells Harboring Efgr Kinase Domain Mutations, Rutu Gandhi

Master's Theses

Lung cancer is the leading cause of cancer related death, accounting for one third of all deaths from cancer worldwide. About 85-90% of lung cancers are non-small cell lung cancers (NSCLCs). Molecular targeted therapies such as epidermal growth factor receptor tyrosine kinase inhibitors (EGFR TKIs) provide an effective treatment option for oncogene addicted NSCLC. However, the development of resistance to EGFR TKIs continues to be the major limitation in the treatment of NSCLC. Resistance to EGFR TKIs has been associated with the loss of canonical epithelial protein E-cadherin, suggesting involvement of epithelial to mesenchymal transition (EMT) in conferring EGFR TKI …

Identifying And Characterizing The Degradative Pathway Of The Retroviral Restriction Factor Rhtrim5Α, Rachel Nelson

Master's Theses

Human immunodeficiency virus 1 (HIV-1) is a lentivirus that progresses to acquired immunodeficiency syndrome (AIDS). The protein TRIM5alpha from rhesus macaques (rhTRIM5alpha) restricts HIV-1 by blocking infection after entry of the virion into cells. Treatment of rhTRIM5alpha expressing cells with inhibitors to a cellular degradation pathway, the proteasome, partially relieves restriction but does not inhibit rhTRIM5alpha protein turnover. The role of a second degradation pathway, the autophagy-lysosomal pathway, in TRIM5alpha mediated restriction has not been explored.

In the present study, we demonstrate that rhTRIM5alpha is degraded by chaperone mediated autophagy (CMA). Inhibition of CMA alters rhTRIM5alpha localization and turnover, while …

Development Of Cell Based Reporter Assay To Measure Pkc-Delta Promoter Activity, Kushal Prajapati

Master's Theses

Protein kinase C- δ (PKC-δ) acts as a tumor suppressor in skin cancer and is lost in 30% of human Squamous Cell Carcinoma (SCC). This loss is at the transcriptional level and involves the pathway leading to PKC-δ promoter repression after activation of Ras,PI3K,Fyn, and NF-κB. We proposed development of a high throughput, cell-based luciferase reporter assay on Ras transformed keratinocyte cell line, HaCaT-Ras to screen compounds having potential to inhibit this pathway and re-induce PKC-δ expression. First we developed a stable, PKC-δ promoter-reporter transfected HaCaT-Ras cell line. Next, we tested 13 compounds for their abilities to induce PKC-δ …

Social-Environmental Predictors Of Health-Related Quality Of Life In Youth With Spina Bifida, Caitlin Beth Murray

Master's Theses

Health-related quality of life (HRQOL) is a multidimensional construct including an individual's physical and mental health and psychosocial well-being (De Civita et al., 2005), and the measurement of HRQOL has been recognized as a key marker of health outcomes in pediatric populations (Eiser & Jenney, 2007). Due to medical and technological advances, an increasing number of individuals with chronic illnesses are living longer. As such, research that investigates improvements in HRQOL in youth with chronic illnesses has become essential. Indeed, the number of studies examining HRQOL in pediatric populations has increased markedly; spina bifida (SB) is one among several chronic …

Conspiratorial Thinking: How Worldview And Mortality Salience Affect Belief, Eric James Anderson

Master's Theses

Conspiratorial thinking is widespread throughout the world, though the major social sciences have thus far chosen not to study them for a variety of reasons. This study attempts to understand what, in fact, makes individuals believe in conspiracy theories. Using aspects of terror management theory, Kruglanski's theory of lay epistemology, participants' political worldviews, and conspiracy type, this paper will explore what triggers conspiracy-prone individuals to see the world the way they do. It is anticipated that individuals who have thoughts of their death primed in their consciousness will structure the world more rigidly, cling to their worldviews and respond to …

Evidence For Renewal And Reconstitution Of Marginal Zone Macrophages In Young And Aged Mice, Erika Bahamon

Master's Theses

Aging in humans and mice correlates with decline in immune health, affecting both innate and adaptive immunity. Response against blood-borne bacterial pathogens is compromised because of the deterioration of the marginal zones of the spleen and decrease in frequency of marginal zone macrophages (MZM). This thesis asked if low cell turnover is the cause for the decrease of MZM, using cell proliferation to indicate cell turnover in spleens of mice. First, evidence showed MZM proliferation occurred in spleens of young mice and was decreased in the MZM from aged mice. Second, transfer of young bone marrow into old mice replenished …

Factors In Destination Decisions For Cuban Study Abroad, Kari Beall

Master's Theses

In January of 2011, the Obama Administration loosened the regulations on academic travel to Cuba, allowing students to travel to this island nation as part of an academic program. These changes have created an ideal environment in which to study the factors that influence the institutional decision to create a new study abroad program. This is an area that has seen very little if any previous research. This study hopes to investigate the connection between the goals of education abroad as a whole and the reasons a study abroad program, in this case to Cuba, is actually created. Studying the …

Aquatic Macroinvertebrate Response To Invasion And Subsequent Removal Of Typha × Glauca From Great Lakes Coastal Marshes, Kimberly Anne Greene

Master's Theses

Aquatic macroinvertebrates are important in wetland ecosystems; many fish and wildlife species depend upon them for food resources and they aid in nutrient cycling. Wetland macroinvertebrate communities are influenced by plant community composition; as such, this study examined two implications of invasive hybrid cattail, Typha × glauca (Typha), on aquatic macroinvertebrate communities in northern Great Lakes coastal wetlands: 1) how the presence of nearly monotypic stands of Typha alters wetland aquatic macroinvertebrate communities and 2) how manual removal of Typha, via mowing and manual tilling, impacts these invertebrate communities along with wetland plant communities. I found that …

Legislating The Risk Of Light Teachers In 1950s And 1970s America, Kevin Vincent Heffernan

Master's Theses

The existence of gay and lesbian teachers remains for many a dangerous notion. Indeed, education and schooling are terrains in which homosexuality has historically been highly charged. Underlying this are problematic assumptions about the suitability of gays and lesbians as school workers, assumptions that feed into larger questions about gays and lesbians in general. This thesis will explore these assumptions - and their consequences for gay and lesbian teachers - against the backdrop of both the 1950s, when the burgeoning Cold War created an "age of anxiety," and the 1970s, when the rise of the religious right began to transform …

I Am Relieved To Discover My Symptoms Are Normal For My Condition: An Analysis Of Two Irritable Bowel Syndrome Support Communities, Erin Hvizdak

Master's Theses

Symptoms of Irritable Bowel Syndrome (IBS), a "medically unexplained illness," are present in up to 20% of the United States population. Individuals experiencing symptoms of IBS often report that physicians dismiss their experiential and embodied knowledge, leading to a sense of isolation and frustration. Many of these individuals attempt to diminish isolation and also exchange their knowledge in a community setting. In order to enable a more complete understanding of IBS, a survey about community participation was sent to members of a large online support group for IBS located on Facebook, with 81 completed surveys received. Further, an open-ended questionnaire …

Characterization Of Inducible Regulatory T Cells: An Umbilical Cord Blood Model, Rebecca Anne Krier

Master's Theses

The immune system is a group of structures and processes that protect us from disease. To function properly it must recognize a wide variety of pathogens such as viruses and bacteria. T cells play a crucial role in an immune response; however, an overactive immune response can lead to autoimmune diseases, therefore it is important that the immune system has the ability to negatively regulate an immune response. In the periphery, regulatory T cells (CD4⁺CD25⁺Foxp3⁺) are involved in the maintenance of self-tolerance and immune homeostasis. Mechanisms involved in the induction of iTregs from naïve …

The Independent Influences Of Relational And Physical Victimization On Subsequent Physical Aggression In Middle School Children, Michelle D. Mioduszewski

Master's Theses

Using Agnew's strain (1992) and integrative (2005) theory, this study hypothesized that relational and physical victimization would be independently associated with self-reported physical aggression at six months and one year after victimization. Secondary data analysis was conducted using three waves of a longitudinal multisite dataset used for the "Outcome Evaluation of the Teens, Crime, and the Community/Community Works (TCC/CW) Training Program, 2004-2005." Independent variables at wave one were relational victimization occurring none or one time (56.2%), or two or more times (43.8%), and physical victimization occurring none or one time (77.8%), or two or more times (22.2%). The dependent variables …

Identifying Student Perspectives: Addressing The Financial Barriers Facing Low-Income Students In Study Abroad, Lauren Miranda

Master's Theses

International education today is largely concerned with improving diversity throughout study abroad but despite institutional strategies which seek to address the barriers facing underrepresented students, the overall student profile of study abroad remains unbalanced. Cost is continuously deemed the biggest barrier affecting students' ability to study abroad, a burden that is most likely heavily felt by low-income students. Therefore, the focus of this study is to identify the student perspective in relation to the financial barriers affecting low-income students' intent to study abroad. The results of this study will identify necessary student resources which institutions like Loyola University Chicago can …

Activity Patterns And Spatial Resource Selection Of The Eastern Garter Snake (Thamnophis Sirtalis Sirtalis), Matthew Gregory Most

Master's Theses

Snake species usually exhibit seasonal variations in activity patterns, home-range size and the use of respective habitat. Using mark-recapture protocols I marked 96 individual Thamnophis sirtalis sirtalis specimens in Lake Forest, IL to determine the independent variables that best explained habitat selection in a population of Eastern Garter Snakes (T. s. sirtalis). Specifically, I focused on the relationship between seasonal movement and home range size of male and female garter snakes. I analyzed the habitat preferences and spatial ecology of Eastern Garter Snakes during the 2011 sampling season and modeled the relationship between preferred or avoided habitat, in conjunction with …

Exosomes: Antiviral Agents In The Human Lung, Jennifer Alexandra Novak

Master's Theses

Hundreds of interferon effectors comprise the immediate host response to virus infection. One family of interferon stimulated genes is the IFITM (Interferon-Induced Transmembrane) proteins. IFITM3, in particular, has been shown to block virus cell entry of Influenza A Virus, SARS Coronavirus, and West Nile Virus, among others. IFITM3 has also been identified as an essential factor for host protection against Influenza A Virus in mice and humans. However, the mechanism by which IFITM3 functions remains unclear.

IFITM3 may function both intracellularly and extracellularly to block virus infection in the human lung. The extracellular milieu contains microscopic vesicles termed exosomes which …

Selective Expansion Of B Cells By Intestinal Microbiota, Karina Ochoa

Master's Theses

In rabbits, antibody diversity and B cell expansion are generated in gut-associated lymphoid tissues (GALT), in an antigen- and T cell-independent mechanism, and require interaction with intestinal microbiota. I investigated, in vitro, the mechanism by which commensals drive GALT reactions. Bacteria were isolated from the GALT of rabbits and identified by 16sRNA sequencing. I found that the commensals can bind to Ig, independently of their specificity. In addition, a ~20kDa bacterial molecule was immunoprecipitated with recombinant Ig molecules. Stimulation of B cells with selected bacterial molecules induced the activation of B cells. Stimulation of B cells through TLR2 induced the …

Secure And Insecure High Self-Esteem And Social Identity Affirmation In Response To Belongingness Threats, Reyna Jacqueline Pena

Master's Theses

The objective of this study was to examine the relation between implicit and explicit self-esteem on social identity affirmation among Latinos in response to belonging threats from other ingroup members. We predicted a three-way interaction between implicit self-esteem, explicit self-esteem, and belonging threat condition predicting social identity affirmation (collective self-esteem), compensatory conviction and ingroup bias. We predicted that individuals with insecure self-esteem (high explicit, low implicit) would affirm their social identity more, offer greater conviction and express more ingroup bias in response to recalled threats as compared to a control condition of non-threatened participants. A total of n=174 Latinos participated …

The Interactive Effects Of Coping Strategies, Gender, And Stress In The Prediction Of Internalizing Symptoms In African American Youth: An Application Of The Specificity Model, Cynthia Pierre

Master's Theses

The current study utilized a specificity framework in the examination of interactions among coping strategies, stressor domains, and participant gender in the prediction of depressive and anxiety symptoms. Participants were 273 African American adolescents (6th - 8th; mean age = 12.9; 58% female). Participants completed measures of universal and culturally-relevant coping strategies in response to a stressor. Stressors were coded by raters across dichotomous domains: interpersonality (interpersonal vs. non-interpersonal), duration (acute vs. chronic), controllability (controllable vs. non-controllable), and sexuality (sexual vs. non-sexual). T-tests were conducted to examine differences in reported coping across stress domains. Inconsistent with predictions, mean differences of …