Digital Commons Network^™

Conflict Management Training In Video-Based Teams, Alexis Ward

Master's Theses

In the wake of an emerging economy that demands organizational agility, globalization and an increasing number of independent contractors, corporations have exponentially incorporated virtual teams in their organizations. However, despite their financial and geographical convenience, research has indicated that virtual teams have consistently experienced more conflict and lowered performance and satisfaction levels than that of their traditional counterparts. The present study sought to examine whether conflict management training could help video based virtual teams demonstrate more positive conflict handling techniques and less negative techniques, which would result in higher group process and group outcome satisfaction. This study did not find …

California Livestock Owners: An Assessment Of Familiarity With New Antimicrobial Rules And Access To Educational Outreach, Philip Theodor Paulson

Master's Theses

The purpose of this research is to support the California Department of Food & Agriculture (CDFA) with education and outreach about recent changes regarding antimicrobial use in livestock, and to enhance their emergency communications network. This was done by characterizing a population of small-scale livestock owners underserved with regards to educational outreach about animal health issues, such as antimicrobial use rules. The project also seeks to enhance public understanding of the importance of responsible antimicrobial use in animal and human health.

To accomplish this, the study used a survey administered in person at local farm supply stores and online to …

Habitat Associations And Community Interactions Of Non-Native Species In The Southern Basin Of Lake Michigan, Erin O'Shaughnessey

Master's Theses

Non-native crayfishes, mollusks, and macrophytes can have large impacts on biodiversity and damage ecosystem services in freshwaters. In 2015 we discovered an established population of the globally widespread invader red swamp crayfish (Procambarus clarkii) in the North Shore Channel of the Chicago Area Waterway System. This population overlaps with a population of rusty crayfish (Faxonius rusticus), a previous invader that is widely distributed and usually the dominant crayfish species across the Great Lakes region. I studied the interactions between these two species while directly competing over shelter and food. In the field, each species was studied to determine the rate …

Opioid Misuse Detection In Hospitalized Patients Using Convolutional Neural Networks, Brihat Sharma

Master's Theses

Opioid misuse is a major public health problem in the world. In 2016, 11.3 million people were reported to misuse opioids in the US only. Opioid-related inpatient and emergency department visits have increased by 64 percent and the rate of opioid-related visits has nearly doubled between 2009 and 2014. It is thus critical for healthcare systems to detect opioid misuse cases. Patients hospitalized for consequences of their opioid misuse present an opportunity for intervention but better screening and surveillance methods are needed to guide providers. The current screening methods with self-report questionnaire data are time-consuming and difficult to perform in …

Role Of Daxx As A Predictive Biomarker In Breast Cancer, Michelle Lucia Fernandez

Master's Theses

Breast cancer is the most commonly diagnosed form of cancer in women, besides skin cancer, and second only to lung cancer for cause of mortality. It is divided into three subtypes, depending on different molecular or pathologic characteristics, including estrogen or progesterone receptor-positive (ER/PR+), human epidermal growth factor receptor-2-positive (HER2+) and triple negative breast cancer (TNBC). There are several therapies used to target these subtypes, but there is still a chance that the cancer will recur into a more aggressive, resistant form even if the therapies were successful before. This recurrence is believed to be due to the Cancer Stem …

Molecular And Biochemical Phenotypes Underlying Reactive Astrocytosis In Primary Optic Nerve Head Astrocytes, Anita Kirti Ghosh

Master's Theses

Glaucoma is a progressive optic neuropathy that manifests in a pathological triad of optic nerve head remodeling, damage to optic nerve axons, and retinal ganglion cell death. Optic nerve head astrocytes (ONHAs) are the primary cell type in the optic nerve head. ONHAs undergo reactive astrocytosis, an activated phenotype characterized by altered gene and protein expression and increased cell migration and proliferation, early in the disease pathology. Reactive astrocytosis is thought to underlie optic nerve head remodeling. The first goal of this thesis was to determine if exposure of primary adult rat ONHAs to hyperbaric pressure (25-30 mm Hg above …

Longitudinal Urinary Microbiome Studies: A Need To Transition To Voided Urine, Baylie Hochstedler

Master's Theses

It is now established that the bladder is not sterile; it contains communities of microbes (microbiota). While the healthy bladder microbiota have been defined using expanded quantitative urine culture (EQUC) and urines obtained by transurethral catheterization (TUC), longitudinal and population studies have not previously been possible. These studies cannot be done using TUC urines, as it would be impractical to catheterize participants daily. Instead, we must transition to using voided urines.In order to make this switch, we have addressed three main issues raised by using voided urine. First, we showed that EQUC out performs standard urine culture on voided urines …

Synthesis And Screening Of Novel Hybrid Benzothiazoles In U-87 Mg Glioblastoma Cell Line, Priscilla Kyi

Master's Theses

Benzothiazole is a heteroaromatic compound known for its wide range of bioactivities including anti-cancer, anti-viral, anti-microbial, anti-inflammatory, anti-convulsant, anti-diabetic, anti-helminthic, and anti-tubercular activities. Research has shown that derivatives of benzothiazole exhibit inhibition of proliferation via apoptosis in various human cancer cell lines, such as liver cancer (Wang, et. al., 2011). In this study, a series of novel hybrid benzothiazole α-cyanostilbene derivatives and styrylbenzothiazole derivatives containing boronic acid and non-boronic acid pharmacophores were synthesized. The anti-cancer and anti-invasive properties of selected benzothiazole α-cyanostilbene derivatives on U-87MG glioblastoma cells were investigated in vitro.

U-87MG cells were incubated with synthesized novel hybrid compounds …

The Mission And Role Of Women In Graeco-Roman And Judeo-Christian Contexts, Fabienne Liana Maslet

Master's Theses

The place of women in the world has changed and progressed in the past decades. When I was a young girl, women were not really valued in the Church and in the service for God. There were always excuses not to allow them to serve God and they were rejected in a lot of areas in the Church service. However, the worse thing is that frequently women are the ones who are belittling themselves, who denigrate themselves, who undermine themselves or the capacities that God gave them to be used in Church. This occurs because they had been educated this …

Assessment Of Eastern Massasauga Rattlesnakes (Sistrurus Catenatus) In Berrien County Historical Sites, Roshelle M. Hall

Master's Theses

The Eastern Massasauga rattlesnake (Sistrurus catenatus; EMR) is a small robust pit viper currently found in nine states and the province of Ontario, Canada. Wetland habitats have experienced significant destruction and fragmentation by humans; as a result, the current distribution of the EMR is a fraction of its historic distribution. For this reason, the EMR has been federally listed as threatened. In general, little is known about the current distribution of this rattlesnake (in the southwest corner of Michigan, the size of local populations or their stability and genetic diversity. Much of this knowledge is based upon historical data. My …

Assay Development For The Identification Of Species And Bioactive Compounds Of Morinda Citrifolia (Noni) In Dietary Supplements By Rt-Qpcr, Dna Sanger Sequencing And Spectroscopy (Uv-Vis/Ftir), Ricardo L. Fernandez Walker

Master's Theses

Regulation standards for dietary supplements lack greatly. Due to this, fraud during the manufacturing of these products might be committed. Previous investigations on herbal dietary supplements have shown that the main ingredient was not present in most of the herbal supplements tested and that these products also contained other substances not stated in the label The purpose of this study was to develop a fluorescent qPCR assay for the identification of Morinda citrifolia herbal species in dietary supplements. Primers for genetic regions rbcL and matK of M. citrifolia were designed. The potential of novel matK primer showed discrimination potential …

Infection Control In Total Knee Replacement Prosthesis Using Nitric Oxide Releasing Biomaterials, Ashley Widing

Master's Theses

Replacing a weight-bearing joint is accompanied by long procedures, even longer recovery times, and intensive monitoring. This burden increases after infection; a complication requiring revision surgeries and therefore extensive additional recovery time. Infection can present itself at any time during the process, making it hard to predict. Currently, a two-part revision surgery is completed by removing all infected tissue and implanting an antibiotic spacer. The spacer fills the joint gap and is removed prior to the revision total knee replacement. A revision total knee replacement follows the same procedure as the initial surgery. Not only is this detrimental to patient …

Mllt3 Regulates Expression Of Genes Critical To Liver Metabolic Homeostasis, Jonathan Richard Dixit

Master's Theses

Hepatic steatosis (fatty liver) is increasingly prevalent in the US, and is characterized by triglyceride accumulation within hepatocytes. This is a direct result of an imbalance between lipid import, export, de novo lipogenesis, and beta oxidation. Hepatic steatosis can also progress to nonalcoholic steatohepatitis (NASH) which is characterized by increased hepatocyte damage, inflammation, and fibrosis. Further progression can lead to liver failure or hepatocellular carcinoma, requiring liver transplant or causing death. Our lab recently created Mllt3 conditional whole body knockout mice. These mice developed hepatic steatosis and NASH following Mllt3 deletion. MLLT3 is a master gene regulator that is part …

The Internal Wave Dynamics Of Barkley Submarine Canyon, Drew Arlen Burrier

Master's Theses

Submarine canyons are prominent bathymetric features in the ocean and in addition to being interesting geological regions, submarine canyons are associated with important physical processes in the ocean. Internal wave reflection from sloping boundaries can cause strong mixing in the turbulent boundary layers near sloping topography. Boundary mixing driven by internal waves may account for a significant portion of the overall oceanic vertical mixing. By observing internal waves using three cabled ADCPs at three sites in and around Barkley Submarine Canyon in spring pre-upwelling, and summer upwelling periods, this thesis has established a strong canyon effect on the internal wave …

Synthesis And Evaluation Of Novel Silica Hydride-Based Stationary Phases For Bioanalytical Applications, Seiichiro Watanabe

Master's Theses

Most HPLC columns are packed with silanol (Si-OH)-rich type-B silica that often participates in undesired electrostatic interactions with sample solutes and produces a poor analyte peak shape. These silanols are also known to facilitate the surface hydration required for HILIC mode to retain polar analytes. However, the hydrated surface composition can easily fluctuate, which results in poor reproducibility and requires a lengthy equilibration step. In this study, four novel stationary phases have been developed by using the TYPE-C™ silica material, in which up to 95% of the surface silanols have been replaced with Si-H group. One of the advantages of …

Phreatomagmatic Eruption Deposits On The Seafloor Record Cataclysmic Caldera Formation On Axial Seamount, Juan De Fuca Mid-Ocean Ridge, Jacob Danielsen

Master's Theses

The physical and compositional characteristics of a unique ash-rich hydrothermal sediment, hydrothermal muddy tuff (HMT), on Axial Seamount, Juan de Fuca Ridge, suggest that it formed by phreatomagmatic eruptions during caldera formation. Deposit thickness trends away from the seamount summit and the presence of 68% primary volcaniclasts and 32% secondary lithics suggest a source from along caldera ring-faults deep in the crust. Lithic geothermometry indicates that the source was subject to low-temperature (<150 >°C) alteration, consistent with a provenance as deep as 600 – 800 m below the seafloor. At this depth, just above the critical point of seawater, the …

Microplastic In Aquatic Food Webs: Museum Specimens And Ingestion Experiments Reveal Controls On Microplastic Ingestion By Freshwater Fish, Loren Hou

Master's Theses

Plastic is pervasive in modern economies and ecosystems. Early research suggests freshwater fish commonly ingest microplastic (particles < 5 mm), which may influence fish digestive tissues, but no studies have examined historical patterns in microplastic consumption or rates of microplastic retention in fish. We measured microplastic in digestive tissue of specimens collected and preserved over the last century (Field Museum, Chicago). We selected Micropterus salmoides (largemouth bass), Notropis stramineus (sand shiner), Ictalurus punctatus (channel catfish), and Neogobius melanostomus (round goby) because each was well represented in the museum collection, with specimens from urban rivers. Specimens from 1900-2018 showed increases in microplastic concentration from the 1950's to present. in a second project, we collected round gobies from Lake Michigan in Chicago to conduct feeding experiments to measure microplastic ingestion and retention rates. the majority of microplastic was excreted within 72 hours of ingestion. Results will aid in understanding ecological interactions of microplastic and freshwater fish, informing further work on the movement of microplastic in aquatic food webs.

Seasonal Diet Variation In Thirteen-Lined Ground Squirrel (Ictidomys Tridecemlineatus) In Southernwestern Michigan, Austin Menzmer

Master's Theses

Thirteen-lined ground squirrels (Ictidomys tridecemlineatus) are omnivorous ground squirrels that range from Texas to Alberta and from Michigan to Utah. The amount and type of both animal and plant matter in their diet may vary both geographically and seasonally. The present study was motivated by prior work, based on δ13C analysis of incisor enamel of thirteen-lined ground squirrels from a colony in southwestern Michigan, suggesting that these animals underwent a pronounced, late-season shift in diet from predominantly C3 to C4 plants. However, this inferred dietary shift was not directly demonstrated. Here, I tracked diet of thirteen-lined ground squirrels in southwestern …

Investigating The Anti-Cancer Properties Of Novel Hybrid 1,4-Dihydropyridine Derivatives In U-87mg Glioblastoma Cell, Tendai Hunyenyiwa

Master's Theses

Glioblastoma is the most devastating of brain cancers with a very high death rate and a low survival rate of less than 15 months after diagnosis. Glioblastoma is a cancer of astrocytes which are the majority of the brain glial cells that support neurons and help create the blood-brain barrier among other functions. The current approach to treating this disease is surgical removal of the main tumor, followed by radiotherapy and limited chemical intervention by the use of temozolomide (TMZ). This disease is characterized by high invasion and recurrence after surgical removal of the main tumor as a result of …

Predicting Spatial Distributions Of Demersal Fishes Off Central California, Anne Catherine Tagini

Master's Theses

Seafloor maps are often used in species distribution modeling (SDM), where maps are paired with fish observations to create models predicting habitat suitability, species density, or species biomass. Problems with the current use of SDM include limited understanding of species relationships with benthic morphology, lack of practical model testing, and deficiency of information on the effects of map resolution on population estimates. A drop camera was used to gather observations of fishes along Central California and paired with remotely sensed bathymetry to create predictive models and maps of species density and biomass. I found that relationships with remotely sensed habitat …

The Whiteness Of The Elephant In The Room: How White Guilt, White Fragility, And Colorblind Racial Ideology Shape Environmental And Social Justice Activism In Santa Cruz County, Robert Michael Foran

Master's Theses

Using frameworks from critical race theory, social movement theory, and community-based activism, this thesis explores the phenomena of white fragility, white guilt, and colorblind racial ideology and how they impact the ways predominantly white-identified social and environmental justice organizations approach, build, and maintain solidarity with communities of color in Santa Cruz County, California. A qualitative approach was employed to investigate the experiences of white-identified activists and how they attempt to engage in this constantly challenging process. Using twenty-two semi-structured interviews and eight group observations, I explored how white-identified individuals negotiate the transformation from ‘moral passivity’ to meaningful, personal relationships with …

Assessment Of Peregrine Falcon (Falco Peregrinus Anatum) Nesting Habitat In The San Francisco Bay Area, Prabha Venu

Master's Theses

Human encroachment into natural environments fragments and degrades the habitat for many species and raptors such as the peregrine falcon (Falco peregrinus) have adapted to the urban environment, co-existing with humans and other wildlife. The habitat preference of the American peregrine falcon subpopulation, F. p. anatum was investigated in the densely urbanized San Francisco Bay Area. In this research, Geographic Information Systems (GIS) applications to evaluate ten environmental attributes and their influence on 47 nesting sites were used. Distances from peregrine falcon nesting sites to two federally listed prey species the California least tern (Sterna antillarum browni) and the western …

Diversity Training Outcomes: Assessing Impact Of Diversity Training On Attitudes Towards Societal Diversity And Cognitive Empathy, Iris Lenette Smith

Master's Theses

Understanding the perspectives of others and appreciating their differences are important due to diversity increasing in society. However, research on diversity has seldom examined the ineffectiveness of diversity training on attitudes towards societal diversity and cognitive empathy. The present study was conducted to examine how diversity training affects one’s attitudes toward societal diversity and cognitive empathy. It was hypothesized that attitudes towards societal diversity and cognitive empathy would improve as a result of diversity training. Gender and ethnicity were also hypothesized to interact with diversity training such that women and ethnic minorities would show more positive attitudes towards societal diversity …

Hes1 Notch Response Elements And Their Roles In Rbpj-K Binding, Michael Majid Khayat

Master's Theses

The Notch signaling pathway is a one of few fundamentally conserved signal transduction pathways critical for metazoan cellular development. Upon ligand activation, the Notch intracellular domain (NICD) translocates to the nucleus and forms a transcription complex with C-binding promoter factor-1 (RBPJ-k/CBF-1/Suppressor of Hairless) and Mastermind-like protein (MAM). The DNA-binding factor, RBPJ-k, binds to a response element containing a consensus sequence of RTGRGAR (where R is G or A). When RBPJ-k interacts with the NICD and MAM, Notch target genes are activated. The most well-characterized gene for Notch is Hes1. Hes1 contains four Notch response elements (NREs), labeled NRE 1-4. Of …

Reproductive Performance, Foraging Effort, And Diet Of An Apex Predator, The Common Murre, At One Of The Largest Nesting Colonies In The California Current System, Stephanie Rianne Schneider

Master's Theses

Common Murre (Uria aalge) are the most abundant avian apex predator nesting in the California Current System (CCS) and nesting is the most energetically demanding phase of their lifecycle. The preyscape within flight distance of their nesting colony determines whether murres produce young, how hard they must work to do so, and what prey types are available to them. This study characterized the reproductive performance, foraging effort, and prey composition of murres nesting at a previously unstudied and large nesting colony in the CCS, Castle Rock National Wildlife Refuge, over an 11-year period (2007 - 2017) intended to capture a …

The Effects Of Parathyroid Hormone And Bisphosphonate On The Cartilage And Subchondral Bone Of The Temporomandibular Joint, Alexandro De Araujo Lima

Master's Theses

Introduction:Parathyroid hormone increases bone strength primarily by stimulating bone formation, whereas Bisphosphonate, an antiresorptive drug, reduce bone resorption by blocking osteoclast activity. Here we examined the effects of alendronate (ALN), a type of bisphosphonate, and we also examine the effects of parathyroid hormone (PTH), which has an anabolic effect and increases bone remodeling when treated intermittently (I-PTH). I-PTH treatment leads to increased bone volume fraction, tissue density and trabecular thickness of the subchondral bone. I-PTH treatment also increases proteoglycan synthesis with a concomitant increase in mineralization of the Mandibular Condyle Cartilage (MCC). We hypothesize that combined treatment of I-PTH …

Low Plasma Hdl Cholesterol Is Associated With Greater Risk For Cardiovascular Disease In Subjects With Metabolic Syndrome, Hana M. Alyousef

Master's Theses

Low plasma HDL cholesterol (HDL-c) has been recognized as a biomarker of cardiovascular disease (CVD) and diabetes. Also, low HDL-c is one of the characteristics of metabolic syndrome (MetS).

Objective: To assess whether low HDL-c and/or low HDL functionality are associated with higher risk for CVD in subjects classified with MetS.

Methods: Forty-subjects with MetS (11 men /29 women, 52.4 ± 9.5 years participated in the study. Anthropometric data [weight, height, BMI, waist circumference (WC), blood pressure (BP)], fasting plasma biomarkers [lipids, glucose, liver enzymes: alanine aminotransferase (ALT), and aspartate aminotransferase (AST), plasma insulin, and glycosylated hemoglobin (HbA1c)], biomarkers of …

Sex-Specific Hatch And Growth Patterns In Young-Of-The-Year Atlantic Silversides (Menidia Menidia, Atherinopsidae) From Mumford Cove, Connecticut, Julie W. Pringle

Master's Theses

The Atlantic silverside (Menidia menidia) is an important semelparous forage fish along the North American Atlantic coast and a well-known model for experimental studies. However, ecological and evolutionary theories, such as the adaptive significance of temperature-dependent sex determination (TSD), have yet to be tested using M. menidia juveniles from their natural habitat. Additionally, how the characteristics of survivors at the end of their growing season are shaped by growth and mortality is insufficiently understood. This study used otolith microstructure analysis to determine sex-specific size-at-age, growth, and hatch date distributions in young-of-the-year juveniles sampled monthly between October-December 2015 in …

Adaptations Of 3d Printing Technology To Microfluidics Systems For The Detection Of Multi-Protein Cancer Biomarkers, Ketki Bhalerao

Master's Theses

The overall goal of research in our group has been to develop devices and use techniques for rapid, easy detection that would also be fully automated, highly sensitive, cost effective and involves multi-protein detection with moderate to high throughput with respect to the increasing need in clinical diagnostics of today. The devices used are developed using 3D printing technology and the methodology used was based on the generation of chemiluminescence (CL), which is obtained by applying a fixed voltage and then measured with a CCD (Charge Coupled Device) camera as a detector. The chemiluminiscense replaces the colorimetric detection of proteins …

Tall Tales Of Danger And Security: How A Critical Human Security Approach Can Address Major Contradictions Revealed Through A Critical Narrative Analysis Of Dominant U.S. Security Strategies, Stephen Schneider

Master's Theses

Over many generations, humans have developed many perspectives and practices regarding the best ways to recognize and address what they perceive to be dangerous. Stories are used to help shape and narrate perceptions about the world, and they serve to pass on vital information that impacts how a society responds to threats and vulnerabilities. These narratives of danger and security are subjective to the experiences and political intentions of society, and therefore in many ways are partial and biased in their assessments and policies. This results in flawed security practices that may actually exacerbate threats or create new insecurities. What …