Digital Commons Network^™

Onshore Habitat Use As A Driver Of Diet, Contaminant Exposure, And Immune Function Of Southern Beaufort Sea Polar Bears (Ursus Maritimus), Jennifer Bourque

Master's Theses

No abstract provided.

A Survey Of New England Sheep Producers, Arielle L. Halpern

Master's Theses

No abstract provided.

Predicting Children Missed By An Early Autism Screener, Cara Cordeaux

Master's Theses

Recent clinical best-practice guidelines from the American Academy of Pediatrics recommend that all children be screened for ASD at 18 and 24 months of age (Johnson & Myers, 2007), and those have contributed to an emphasis on early screening and diagnosis. However, no screening instrument can identify all cases at 18-24 months. This study examined profiles of 135 children who participated in validation studies of the Modified Checklist for Autism in Toddlers (MCHAT, MCHAT-R/F), an ASD specific screening instrument. Participants were screened at 18-24 months (Time 1) and again at 36-48 months (Time 2). Children who screened negative at 18-24 …

The Impact Of Junk Food Marketing Regulations On Food Sales: An Ecological Study, Yumi Kovic

Master's Theses

Objectives. To evaluate the impact of junk food marketing policies implemented worldwide from 2003 through 2014 on nationwide junk food sales and to identify the most effective policy characteristics in reducing junk food sales.

Methods. Junk food marketing policy data were obtained and categorized through a thorough literature review. These data were analyzed using a repeated measures design against EuroMonitor junk food sales data from 2002 and 2016.

Results. Countries with junk food marketing policies saw a decrease in junk food sales after implementation, while those without said policies saw an increase in sales. Countries with statutory policies saw a …

Reanalysis Of The Usher Syndrome Type 2 Carrier As “Phenotype-Free”, Peter Perrino

Master's Theses

No abstract provided.

Thermophysical Properties And Characterization Of Diamond Silicon Carbide, Alexandra Merkouriou

Master's Theses

No abstract provided.

Small Rna Sequencing And Rt-Qpcr Validation Of Forensically Relevant Body Fluids, Karly Johannsen

Master's Theses

Body fluid identification is an important aspect of forensic investigations because it assists with the reconstruction of crime scenes and can refute and/or support witness statements. Currently, there is no universal method for body fluid identification. Each body fluid has several tests for its identification, both presumptive and confirmatory. A universal method for body fluid identification that is sensitive, specific, efficient, and minimally destructive is necessary.

In recent years miRNAs have been heralded as novel biomarkers for the identification of body fluids. Several research groups across the US and internationally have been formed to determine which miRNAs are suitable for …

Naatm1: Examining The Mechanism Of A Heavy-Metal Abc Exporter, Dennis Hicks

Master's Theses

ATP-Binding Cassette (ABC) Transporters are a superfamily of integral membrane proteins that have been found embedded in both the cellular membranes and internal organelles of all species yet analyzed (1). This extreme conservation throughout the tree of life is due to their vitally critical and broad task of transporting all manner of things into and out of the cell and related organelles. This broadness of responsibility has led to an abundant diversity of this family, which in turn, has allowed life to adapt to the many environments found on Earth. While the importance and variability of this family is abundantly …

Construction Of A Reference Allelic Ladder For An Odocoileus Str Multiplex, Jolene Strand

Master's Theses

Odocoileus is a genus of Cervidae (deer) consisting of white-tailed deer (Odocoileus virginianus, Zimmerman, 1780), mule deer (Odocoileus hemionus, Rafinesque, 1817) and blacktailed deer (Odocoileus hemionus hemionus, Rafinesque, 1817). Hunting Odocoileus is only legal with proper permits according to laws that dictate when, where, how, and what can be hunted. Anything outside the legal limits is considered to be poaching. A useful tool for investigating poaching cases is Short Tandem Repeat (STR) DNA analysis. This is commonly used in human forensic casework to link DNA evidence found at crime scenes to either victims or suspects. In poaching cases, it can …

Effect Of Bio-Augmentation Product Biowish® Septic Rescue On The Wastewater Treatment Performance Of Residential Septic Tanks, Kimberly Michelle Lamar Merilles

Master's Theses

Residential septic systems provide reliable wastewater treatment for over 26 million homes and facilities in the United States, and many more worldwide. When properly maintained, these systems are reliable, low-cost, and long-term treatments for residential wastewater. When neglected, septic systems can fail and lead to health concerns and ecological harm to soil and groundwater contamination through the improperly treated wastewater effluent.

This study tested the effect of the bio-augmentation product BiOWiSH® Septic Rescue of BiOWiSH® Technologies International, Inc. (hereafter referred to as BiOWiSH) on the biological treatment of residential septic tanks. BiOWiSH is meant to act as a bio-augmentation product …

Indoor Air Monitoring Of Ethanol And Benzene In A Pilot Winery Using Active Sampling, Andrew I. Kaneda

Master's Theses

Acute indoor concentrations of benzene and ethanol were evaluated in the California Polytechnic State University San Luis Obispo’s pilot winery workroom. Air samples were collected during four different wine-making activities: fermentation, fermentation with Brix content testing, post-alcoholic fermentation pressing, and storage/finishing. Average workroom benzene concentrations ranged from 0.05 to 0.12 mg/m³. Ethanol concentrations in the winery workroom varied with the activity, ranging from 0.9 to 12 mg/m³. Pressing and fermentation with Brix content testing both led to higher indoor ethanol concentrations than fermentation without Brix content testing and storage/finishing.

Tracer gas decay air exchange tests were …

The Effect Of Alcohol And Bitterness Levels On Brewing Yeast Viability, Nichole Elizabeth Bryant

Master's Theses

Two of the most popular beer styles within the craft brewing industry are India Pale Ales (IPA’s) and those with high alcohol by volume (ABV). Production of these styles requires high gravity fermentation and high amounts of bittering hops in order to reach the required values for ABV and International Bitterness units (IBU) respectively. The aim of this study was to determine the impact of high gravity fermentation and high IBU levels on yeast viability and repitching cycles.

An initial experiment on high gravity fermentations was done in order to assess the effects this variable had alone. Successive five day …

Perturbation Based Decomposition Of Semg Signals, Rachel Huettinger

Master's Theses

Surface electromyography records the motor unit action potential signals in the vicinity of the electrode to reveal information on muscle activation. Decomposition of sEMG signals for characterization of constituent motor unit action potentials in terms of amplitude and firing times is useful for clinical research as well as diagnosis of neurological disorders. Successful decomposition of sEMG signals would allow for pertinent motor unit action potential information to be acquired without discomfort to the subject or the need for a well-trained operator (compared with intramuscular EMG). To determine amplitudes and firing times for motor unit action potentials in an sEMG recording, …

Wastewater Treatment And Nitrogen Removal In Bench-Scale Photobioreactors Operated With Solids Recycling, Erik Hoffnagle

Master's Theses

This thesis examines the effect of solids recycling on nitrification, organic carbon removal, and algal-bacterial productivity in bench-scale photobioreactors (PBRs) simulating winter pond conditions in San Luis Obispo, California and a 6-acre raceway system in Delhi, California. Two sets of duplicate photobioreactors operated with or without solids recycling were fed primary clarifier effluent (1^oEff) for the first experiment, and facultative pond effluent (FAC) for the second experiment.

In both experiments mean productivity was lower in solids recycled PBRs (3.67 and 2.3 g/m²-day), than in controls without solids recycling (4.15 and 3.9 g/m²-day). When fed …

Avian Use Of A Bottomland Hardwood Afforestation Site In The Red River Alluvial Valley, Colby W. Sharp

Master's Theses

Bottomland hardwood forests (BHF) cover about 2.8 million hectares of the original 10 million hectares that once existed in the southeastern United States. These losses have led to an emphasis on afforestation of retired agricultural land. Research was needed to evaluate changes in wildlife communities as these afforested stands progress through succession. To assess the avian community at this 25-year-old afforested BHF, I conducted point count surveys at 28 point locations across seven forest types, six times during the 2016–2018 avian breeding seasons. My research objectives were to determine: (1) if avian density and diversity varied among the dominant forest …

Effectiveness Of Windrow Composting Methodology In Killing A Thermo-Tolerant Species Of Salmonella During Mortality Composting, Spencer Gabriel Myers

Master's Theses

In a large agricultural operation, such as the one at Cal Poly San Luis Obispo, disposal of deceased animals is an immense issue. The cost of transporting and rendering every dead animal is inhibitory to the general function of the agricultural operations and their thin budget. Therefore, we propose that composting mortalities could be an economical alternative. Composting is a recognized method for taking animal waste products along with carbon waste and turning it into a pathogen-free, nutrient-rich topsoil. Carcass composting is in fact performed in other countries and states to varying degrees of success. However, the California EPA limits …

Conflict Management Training In Video-Based Teams, Alexis Ward

Master's Theses

In the wake of an emerging economy that demands organizational agility, globalization and an increasing number of independent contractors, corporations have exponentially incorporated virtual teams in their organizations. However, despite their financial and geographical convenience, research has indicated that virtual teams have consistently experienced more conflict and lowered performance and satisfaction levels than that of their traditional counterparts. The present study sought to examine whether conflict management training could help video based virtual teams demonstrate more positive conflict handling techniques and less negative techniques, which would result in higher group process and group outcome satisfaction. This study did not find …

Pro Or Bust: Career Aspirations Of Division I And Community College Basketball Players, Alexander Shahriar Engel

Master's Theses

ABSTRACT

Pro or Bust: Career Aspirations of Division I and Community College Basketball Players

Alexander Shahriar Engel

The purpose of this study was to determine the difference, if any, between Division I and community college basketball players career aspirations. Interviews were held with eleven athletes from the Cal Poly Men’s Basketball team, and ten athletes from the Cuesta College Men’s Basketball team. The interviews were used to determine the impact of different variables on the athletes career aspirations, and to explore themes in the data. To look for themes, both axial and open coding was used. Division I athletes were …

Adolescent Binge Alcohol Exposure Effects On Heart Structure And Function, Lizhuo Ai

Master's Theses

More than 5 million underage Americans report binge drinking at least once per month. While the effects of alcohol consumption on the adult heart have been well studied, the impact to the adolescent heart is almost entirely unknown. Adolescents primarily consume alcohol in a binge pattern, which elevates blood alcohol content (BAC) to 0.08 g/dL within 2 hours. During adolescence the body grows rapidly, and the heart must also grow by cellular hypertrophy to meet this increasing demand. Our goal was to determine the impact of adolescent binge alcohol exposure on the heart, using an outbred rat model. This thesis …

California Livestock Owners: An Assessment Of Familiarity With New Antimicrobial Rules And Access To Educational Outreach, Philip Theodor Paulson

Master's Theses

The purpose of this research is to support the California Department of Food & Agriculture (CDFA) with education and outreach about recent changes regarding antimicrobial use in livestock, and to enhance their emergency communications network. This was done by characterizing a population of small-scale livestock owners underserved with regards to educational outreach about animal health issues, such as antimicrobial use rules. The project also seeks to enhance public understanding of the importance of responsible antimicrobial use in animal and human health.

To accomplish this, the study used a survey administered in person at local farm supply stores and online to …

The Role Of Polyamines In Enteroviral Attachment, Thomas Mckenzie Kicmal

Master's Theses

Polyamines are small polycationic molecules with flexible carbon chains that are found in all eukaryotic cells. Polyamines are involved in the regulation of many host processes and have been shown to be implicated in viral replication. Depletion of polyamine pools in cells with FDA approved drugs restricts replication of diverse RNA viruses. Viruses can exploit host polyamines to facilitate packaging, transcription, translation, and protease activity but other mechanisms remain largely unknown. Picornaviruses, including Coxsackievirus B3 (CVB3), are sensitive to depletion of polyamines and remain a significant public health threat. We employed CVB3 as a model system to investigate a potential …

Dissecting A Role For Polyamines In Rift Valley Fever Virus Infection, Vincent Mastrodomenico

Master's Theses

Bunyaviruses are emerging viral pathogens that cause encephalitis, hemorrhagic fevers, and meningitis. Rift Valley fever virus is a particularly devastating bunyavirus, infecting both humans and livestock with significant morbidity and mortality. By coordinating several host and viral processes Rift Valley fever virus is able to produce infectious virions. Polyamines are small, positively-charged host-derived molecules that play diverse roles in human cells and in infection. We previously demonstrated that polyamines are crucial for RNA viruses; however, the mechanisms by which polyamines function remain unknown. Here, we investigated polyamines' role in the replication of the Rift Valley fever virus (vaccine strain MP-12). …

Habitat Associations And Community Interactions Of Non-Native Species In The Southern Basin Of Lake Michigan, Erin O'Shaughnessey

Master's Theses

Non-native crayfishes, mollusks, and macrophytes can have large impacts on biodiversity and damage ecosystem services in freshwaters. In 2015 we discovered an established population of the globally widespread invader red swamp crayfish (Procambarus clarkii) in the North Shore Channel of the Chicago Area Waterway System. This population overlaps with a population of rusty crayfish (Faxonius rusticus), a previous invader that is widely distributed and usually the dominant crayfish species across the Great Lakes region. I studied the interactions between these two species while directly competing over shelter and food. In the field, each species was studied to determine the rate …

Opioid Misuse Detection In Hospitalized Patients Using Convolutional Neural Networks, Brihat Sharma

Master's Theses

Opioid misuse is a major public health problem in the world. In 2016, 11.3 million people were reported to misuse opioids in the US only. Opioid-related inpatient and emergency department visits have increased by 64 percent and the rate of opioid-related visits has nearly doubled between 2009 and 2014. It is thus critical for healthcare systems to detect opioid misuse cases. Patients hospitalized for consequences of their opioid misuse present an opportunity for intervention but better screening and surveillance methods are needed to guide providers. The current screening methods with self-report questionnaire data are time-consuming and difficult to perform in …

Zero Tolerance And Self Image: A Systematic Literature Review, Caitlyn Todd

Master's Theses

The use of zero tolerance disciplinary policies in schools have numerous, lasting impacts on children, particularly African American students. This study relies on the use of a systematic literature review to analyze prior data on what these effects are. The study found that the effects include, but are not limited to, destruction of self confidence, increased recidivism, and lastly further psychological issues, all of which contribute to the likelihood of having a poor self image. These findings play are role in the discussion of other, more equitable, styles of discipline, such as restorative justice, as a way to help remedy …

A Possible Role Of Clostridium Difficile Association With The Gi Tract In Relapsing Clostridium Difficile Infection, Asiyya Ashraf

Master's Theses

Clostridium difficile infection (CDI), caused by the anaerobic spore-former C. difficile, is a major cause of health-care associated morbidity. CDI occurs in individuals that have a disrupted GI tract microbiota, typically in patients who are on antibiotic therapy. After recovery from an episode of CDI, approximately, 15-30% of patients experience relapse of disease. The mechanism of relapse is not well understood. It is plausible for relapse to occur if C. difficile cells and spores associate with the GI tract mucosa during infection and persist after infection. However, little is known about the association of cells and spores with the GI …

Assessing The Role Of A Putative Peptidase In The Processing And Transport Of Aip In The Agr Quorum Sensing System Of Staphylococcus Aureus, Chance Joseph Cosgriff

Master's Theses

Staphylococcus aureus infections are a global burden on human health. The wide rangeof infectious diseases caused by S. aureus stem from the production of myriad virulence factors that manipulate host immune responses and promote bacterial survival. These virulence traits, coupled with the rise in antibiotic resistance, demonstrate a need for novel therapeutics to control infection. Many current therapeutic initiatives focus on targeting the virulence factors produced by S. aureus or the regulatory systems that control their expression such as the Accessory gene regulatory system, Agr.Initial characterization of a putative S. aureus peptidase MroQ indicates a major role in regulation of …

Modulation Of Coxsackievirus Protease Activity By Polyamines, Courtney Noelle Dial

Master's Theses

Coxsackievirus type B (CVB3) is one of the six serotypes of the Coxsackievirus family of non-enveloped, linear, and positive-sense single-stranded RNA viruses. It is a pathogenic enterovirus that belongs to the same genus as the notable pathogen poliovirus. CVB3 can cause a range of illnesses from a fever to gastrointestinal distress but is most noteworthy for the ability to cause viral myocarditis, a swelling of the heart muscle. Coxsackievirus, like all RNA viruses, tends to develop mutations rapidly due to its error prone polymerase and lack of proofreading activity. These mutations can be advantageous for the virus, allowing it to …

Molecular And Biochemical Phenotypes Underlying Reactive Astrocytosis In Primary Optic Nerve Head Astrocytes, Anita Kirti Ghosh

Master's Theses

Glaucoma is a progressive optic neuropathy that manifests in a pathological triad of optic nerve head remodeling, damage to optic nerve axons, and retinal ganglion cell death. Optic nerve head astrocytes (ONHAs) are the primary cell type in the optic nerve head. ONHAs undergo reactive astrocytosis, an activated phenotype characterized by altered gene and protein expression and increased cell migration and proliferation, early in the disease pathology. Reactive astrocytosis is thought to underlie optic nerve head remodeling. The first goal of this thesis was to determine if exposure of primary adult rat ONHAs to hyperbaric pressure (25-30 mm Hg above …

A Comparison Of The Relationship Between Gender Adherence, Sex, And Attitudes Toward Individuals With A Mental Illness, Brooke Reimer

Master's Theses

Attitudes toward persons with a mental illness consist of four main dimensions: Authoritarianism, benevolence, social restrictiveness, and community mental health ideology. Attitude differences on these dimensions have been found among many types of groups, including age, race, and educational attainment. Sex and gender adherence have been cited as other such factors, but two major issues are present: past researchers have reported inconsistent findings regarding attitude differences and the terms are used interchangeably in research literature despite conceptual differences. Using data from 187 individuals from a survey, the current study tested sex differences and gender adherence differences in attitude toward mental …