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Articles 31 - 33 of 33
Full-Text Articles in Entire DC Network
Insulin Sensitivity Effects On Peripheral Vascular Responses To Fmd In Metabolic Syndrome Women., Ariel Gomez, Klaudia Szych, Annajita A. Rubio, Shannon Jackson, Matthew A. Barlow
Insulin Sensitivity Effects On Peripheral Vascular Responses To Fmd In Metabolic Syndrome Women., Ariel Gomez, Klaudia Szych, Annajita A. Rubio, Shannon Jackson, Matthew A. Barlow
International Journal of Exercise Science: Conference Proceedings
Sedentary populations with obesity and metabolic syndrome (MetSyn) have presented with impaired vascular dysfunction, including vasodilation reduced 40-50%. The mechanisms of vascular endothelial dysfunction has also been associated to the bioavailability of nitric oxide levels and in metabolic compromised individuals the diminished content of endothelial NO are a prime mechanistic target for study. PURPOSE: We hypothesize that decreased reactive hyperemia observed in MetSyn compared to age matched-control patients are primarily due to mechanistic dysfunction of the eNOS pathway and lower Insulin Sensitivity Index (ISI). METHODS: 30 participants (10 MetSyn and 20 Controls) completed brachial FMD testing and vascular …
The Effect Of Sedentary Behavior On Arterial Stiffness In Healthy And Metabolic Syndrome Women, Annajita A. Rubio, Ariel Gomez, Klaudia Szych, Matthew A. Barlow
The Effect Of Sedentary Behavior On Arterial Stiffness In Healthy And Metabolic Syndrome Women, Annajita A. Rubio, Ariel Gomez, Klaudia Szych, Matthew A. Barlow
International Journal of Exercise Science: Conference Proceedings
Overweight and obese physical stature has been associated with increased endothelial dysfunction and the development of cardiovascular disease. This dysfunction may further be progressed as this population develops Metabolic Syndrome and Diabetes. To understand the mechanisms responsible for the vascular dysfunction in the Metabolic Syndrome participants in our research study, we aimed to identify if there is a difference in the Pulse Wave Velocity (PWV) as an effective measurement of peripheral arterial stiffness. Previous studies show that adults with higher superficial femoral artery stiffness experienced greater perceived fatigue and thus are less likely to continue daily physical activity. PURPOSE: …
Quantification Of Sympathetic Transduction In Type 2 Diabetes Patients, Ben E. Young, Jennifer R. Vranish, Seth W. Holwerda, David M. Keller, Paul J. Fadel
Quantification Of Sympathetic Transduction In Type 2 Diabetes Patients, Ben E. Young, Jennifer R. Vranish, Seth W. Holwerda, David M. Keller, Paul J. Fadel
International Journal of Exercise Science: Conference Proceedings
Type 2 Diabetes patients (T2D) have been shown to have greater alpha-adrenergic sensitivity. How this impacts the transduction of muscle sympathetic nerve activity (MSNA) to arterial blood pressure under resting conditions using spontaneous fluctuations in MSNA, as well as during stressors known to elicit sympatho-excitation (e.g., cold pressor test (CPT)) is unclear. PURPOSE: We tested the hypothesis that T2D patients would exhibit greater sympathetic transduction compared to age and BMI-matched, healthy controls. METHODS: MSNA (microneurography), heart rate (ECG), and beat-to-beat arterial blood pressure (finger photoplethysmography) were continuously recorded during a 10 minute baseline period, and in response to a 2minute …