Digital Commons Network^™

Carboxypeptidase O Expression In Ku812 Basophil Cells Decreases Upon Degranulation, Etien Balorda

Honors Theses

Basophils are leukocytes that mediate inflammatory responses through the exocytosis of granules containing enzymes and inflammatory mediators. Carboxypeptidase O (CPO) is a protease with Cterminal acidic amino acid specificity and is expressed in basophils. CPO expression and localization were assessed in KU812 basophil cells via Western blotting and immunocytochemistry. CPO expression decreased upon degranulation and is localized to cytosolic puncta. These data suggest that CPO may be localized in basophil granules and released upon degranulation.

The Ethical Limits Of Physician Autonomy In Reproductive Medicine, Isabel Martens

Honors Theses

In vitro fertilization is a relatively new medical practice that helps people who face infertility be able to reproduce. Reproductive medicine providers face ethical dilemmas often in their field, only some of which have standards of care. There are questions in the medical landscape pertaining to physician autonomy versus patient autonomy, which heavily apply to reproductive medicine providers. Patient autonomy is highly valued in medical ethics; however, physician autonomy should also be considered. When a physician decides who can and cannot reproduce, ethical considerations must be followed to maintain the practice of reproductive autonomy. Limited policies exist that manage reproductive …

Environmental Degradation And Food Systems In Ghana: Gold Mining And Synthetic Pesticides, Da'mirah Vinson

Honors Theses

This research examines the relationship between environmental degradation and food systems in Ghana. Although sociological research has explored how extractive practices like gold mining dispossesses farmers of land (Gilbert and Albert 2016; Agariga 2021; Kwang and Blagogie 2025), the consequences for food sovereignty and security remain understudied. Research that considers food and land from a sociocultural perspective is even more limited. My research addresses these gaps by asking: How do environmental degradation practices—specifically gold mining and chemical use—affect food production, distribution, and security in Ghana? And how does the decline of arable land reshape cultural food identity? To explore these …

The Effects Of Low-Frequency, Low-Intensity Ultrasound On Gene Expression In Macrophage-Endothelial Cell Co-Culture, Evelyn Hergenhan

Honors Theses

Introduction

Low-frequency, low-intensity ultrasound (LFLI US) has been shown to be a promising treatment for noninvasive accelerated chronic wound healing. However, the biological mechanisms of this ultrasound-assisted healing are not yet understood, limiting clinical adoption. The objective of this study is to characterize the effects of LFLI US on gene expression in a simulated chronic wound environment to gain a better understanding of the biological mechanisms underlying this therapeutic.

Methods

A simulated chronic wound environment consisting of endothelial cells and inflammatory M1 macrophages co-cultured in 3D was subject to LFLI US at 50, 100, or 150 mW/cm² Spatial-Peak, Temporal-Peak …

Always Green, Ever Living, Anna Plante

Honors Theses

The Creative Honors Thesis, “Always Green, Ever Living," is an experimental essay film that explores the complexities and contradictions of environmental conservation, up against the contemporary climate crisis. The film is centered on Muir Woods National Monument and follows a young girl's relationship with nature. The film reflects on how protected natural spaces are influenced by systems of funding, access, and interpretation, as well as broader environmental pressures. Using a combination of archival footage, original imagery, narration, and ambient sound, the project adopts the essayistic structure that prioritizes reflection over linear storytelling.

Toward Completeness Theorem For Guarded Kleene Algebra With Tests, Hung Pham

Honors Theses

Code refactoring is a fundamental practice in software engineering, in which a program is restructured without changing the actions it performs and the results it produces. To carry out refactoring with confidence, one requires a formal method for verifying that two programs are equivalent. Guarded Kleene Algebra with Tests (GKAT) provides such a framework, an algebraic system designed to reason about a natural class of programs, namely those in which every branch and loop is governed by a Boolean condition, such as if–else and while statements. Central to GKAT is a finite set of algebraic axioms for deriving program equivalences. …

Temperature-Dependent Optical Properties Characterization Of Thermophotovoltaic Selective Emitter (4h– Sic, Aln Ceramic, And Aln/Al2o3), Po-Chao Huang

Honors Theses

Thermophotovoltaic (TPV) systems convert thermal radiation into electricity, and their efficiency depends strongly on the temperature-dependent optical response of the emitter materials. To support the design of high-temperature selective emitters, we characterized the thermo-optical properties of aluminum nitride ceramic (AlN), silicon carbide (4H– SiC), and aluminum oxide on aluminum nitride (AlN/Al2O3) thin film/substrate pairs, as a promising example of a bilayer emitter. Spectroscopic ellipsometry measurements from 240 nm to 2500 nm were performed while heating samples from room temperature to 600 °C. Using general oscillators modeling, we established accurate temperature dependent optical models consistent with literature values. Increasing temperature revealed …

Leveraging Machine Learning Techniques To Identify Catastrophic Outliers In Photometric Redshift Estimates, Jason Yoo

Honors Theses

Leveraging the unprecedented data volumes from modern astronomical surveys, this work addresses the critical challenge of identifying catastrophic outliers (COs) in photometric redshift (photo-z) estimates. Reliable redshift estimation is essential for precision cosmology, yet COs (galaxies with severely erroneous photo-z) can introduce significant systematic bias. We develop and evaluate two machine learning approaches for robust CO identification: a multilayer perceptron (MLP) utilizing photo-z point estimates and probability distributions, and a convolutional neural network (CNN) leveraging raw 5-band photometric images. Using datasets emulating LSST conditions, we demonstrate that the MLP model achieves high accuracy and stability across redshift bins, correctly identifying …

Hegemonic Microtonality: Decolonizing The Soundscape Of Music Theory Pedagogy, Ash K. Wetty

Honors Theses

This thesis examines how Western music theory pedagogy—long organized around tonal and twelve-tone equal-temperament frameworks—structures both what is taught and how students are trained to listen. Through a literature review tracing the historical construction of tonal universality in undergraduate curricula, the project argues that dominant models of music theory reproduce broader epistemic hierarchies inherited from Western conservatory traditions. Situating these histories within my own experience as a student navigating institutional listening norms, the thesis combines critical self-reflection with ethnographic research conducted across five liberal arts institutions, including the CBB consortium and JanPlan research at Wesleyan University and Amherst College. Rather …

Metamorphosed Components In Cv Chondrites Camel Donga 003 And Camel Donga 040 As Evidence For Varying Degrees Of Metamorphism Within The Parent Body, Kathryn E. Stone

Honors Theses

The CV carbonaceous chondrites are a group of primitive stony meteorites that record early solar-system evolution processes. They are typically of low metamorphic grade, though some metamorphosed CVs have recently been found. Two CV chondrite breccias, Camel Donga 003 (CD 003) and Camel Donga 040 (CD 040) consist of multiple lithologies. CD 003 consists of three lithologies, one of which – Lithology C – has been metamorphosed to petrologic type ~3.7 (Alevy et al. 2025). CD 040 consists of two lithologies, one of which is metamorphosed to petrologic type 3.7 (Dunn and Alevy, 2024; Dunn et al. unpublished). Both samples …

Climate Change And Species Interactions Jointly Shape Migration Timing And Growth At A Critical Ontogenetic Transition In Juvenile Sockeye Salmon, Margaret E. Veatch

Honors Theses

Climate change is shifting the timing of biological events globally, but the mechanisms linking environmental variation to phenological changes are poorly understood in many systems, particularly those where individuals undergo ontogenetic habitat shifts. Here, I examined the join influence of climate-driven environmental variability and species interactions migration timing and body size at migration in juvenile sockeye salmon (Oncorhynchus nerka) in Lake Aleknagik, Alaska, using a multi-decadal dataset (1967–2024). Migration timing varied widely among years and was best explained by a combination of ice-out phenology, epilimnetic temperature, and fish densities in littoral habitats. Juvenile sockeye salmon migrated earlier in …

From Sorochyntsi To St. Petersburg: National Identity In The Works Of Nikolai Gogol, Gary Jay Kogoy Jr.

Honors Theses

Nikolai Gogol's extant works depict a man torn between his birthplace of Ukraine and the nineteenth-century milieu of Imperial Russia. Notably, he did not reveal his name for some time after publishing his first story collection Evenings on a Farm Near Dikanka; as a result, readers attributed the tales of Ukrainian life within not to Gogol, but to the charming "Ukrainian jester" persona of Rudy Panko. Even after revealing his identity and garnering respect in the St. Petersburg literary scene, his contemporaries often viewed him as sly and suspicious because of his ancestry. Perhaps due to external doubts regarding …

"It's A Dance": Examining Midwives As Choreographers Of Reproduction In Maine, Annie Goldstein

Honors Theses

This thesis examines the contemporary work of community-based Maine midwives through the theoretical framework of choreography. In the context of this work, choreography can be understood as the well-thought-out, purposeful undertaking of a process during which negotiation, coordination, and improvisation are required to adapt to constantly changing circumstances. Using choreography, this thesis attempts to understand how Maine midwives navigate global market processes and practice under authoritative forms of biomedicine, ultimately linking them to other midwives across various global sites. Situated within Maine’s maternal health landscape that is characterized by the ongoing closure of labor and delivery units and rural hospitals, …

Ultra-Processed Or Ultra-Addictive? A Demand-Based Redefinition Of Ultra-Processed Foods, Braden Jondro

Honors Theses

Ultra-processed foods now comprise the majority of the U.S. food supply and have been directly associated with 32 chronic diseases including obesity, cardiovascular disease, cancer, and diabetes. Current classification systems such as NOVA provide a useful framework for identifying food processing, but rely on broad and subjective categorizations that may not capture the mechanisms most closely associated with promoting persistent overconsumption. In particular, existing classification systems remain limited in their ability to evaluate addiction-like behaviors associated with highly processed foods, including persistent purchasing patterns, reinforcement effects, and substitution responses. This paper introduces the Ultra-Processed Food Intensity (UPFI) index, an objective, …

Between Commodity And Culture: Tea Advertising As A Site Of Imperial Ideology And Anti-Colonial Resistance In India, Sydney Pascal

Honors Theses

Between the late nineteenth century and Indian independence in 1947, tea advertising became a key site through which imperial authority and Indian nationalism were negotiated. Drawing on advertisements, trade journals, and visual marketing campaigns produced from the 1880s through the 1950s, this honors thesis argues that tea advertising was a cultural and political mechanism through which the British Empire attempted to normalize imperial consumption and legitimize colonial authority. British campaigns framed tea as modern and routine while obscuring the exploitative labor systems and landscape transformations that sustained plantation production in Assam. As nationalist movements expanded in the early twentieth century, …

Blood And Belonging: Remembering Massacres Of The American West In The Twentieth Century, Mountain Meadows And Sand Creek, Kenzie Burns

Honors Theses

The late nineteenth and early twentieth centuries marked a turning point in mainstream America’s sense of national identity. A wave of nostalgia for the American Frontier enshrined the region’s idealized nineteenth-century past as myth. A key part of the story is romanticized violence—often depicted through cultural imagery of cowboys, gunfights, and battles with American Indians. This project seeks to understand more about how violence is represented in the cultural memory of the American Western past. Within the past twenty years, scholars of the American West have begun to incorporate the study of memory into their scholarship, frequently with how cultural …

Brewing Resilience: Cooperatives, Micro-Mills, And The Quest For Survival In Costa Rica's Changing Coffee Landscape, Leila N. Iredell

Honors Theses

This thesis examines how different organizational models in Costa Rica's coffee sector shape producers’ ability to capture value, build resilience, and sustain rural livelihoods in a rapidly changing global market. In comparing traditional cooperatives and new micro-mills, I examine specifically how control over the value chain, access to markets, and social infrastructure differ across models and what these differences mean for the farmers who depend on them. This project analyzes how the collapse of international price agreements and decades of market volatility drove producers toward new strategies, from independent processing and direct trade to coffee tourism. Costa Rica stands as …

Sexual Politics Of The Anglo-American Relationship In 1942: A Case Study Of The United States V. Travis Hammond Court-Martial, Catherine Campbell

Honors Theses

On August 10, 1942, American private, Travis B. Hammond, was on trial for accusations of rape against a 16-year-old British girl, Maureen Thomson. This would mark the first American court martial case tried on British soil. This trial was preceded by the issuing of the United States (Visiting Forces) Act of 1942 (VFA) on August 6, 1942, which granted the United States military exclusive jurisdiction over their soldiers. When the Act was first given to Parliament, it was looked at in disdain as being wholly without precedent and antithetical to the norms within Britain. However, the importance of maintaining a …

Pay Gaps At The Top: How Ceo–Executive Compensation Disparity Affect Firm Performance, Anh Que Diep

Honors Theses

This paper examines the relationship between executive compensation disparity and firm performance using S&P 500 firms. CEO Pay Slice (CPS) is used to measure pay disparity, and firm performance is measured by Tobin’s Q and ROA. The results from fixed effects models show an inverted U-shaped relationship between CPS and firm performance, with performance maximized at approximately a 60% CEO Pay Slice. Further analysis decomposes CPS into fixed and performance-based components. The results show that fixed compensation disparity is positively and consistently associated with firm performance, while performance-based disparity has weaker and less robust effects. Taken together, the findings suggest …

A Critical Discourse Analysis Of Racial Justice In Virginia Higher Education, Abigail Green

Honors Theses

This honors thesis examines the extent to which public Virginia higher education institutions engage their institutional histories in leadership rhetoric when responding to the Trump administration’s anti-diversity, equity, and inclusion (DEI) policies. Employing a Critical Discourse Analysis (CDA) following Mullet’s (2018) seven-step framework with an inductive coding approach and grounded in rhetorical history theory, this study analyzes official statements from the Offices of the President and Provost across four case study institutions: the University of Virginia (UVA), George Mason University (GMU), the College of William & Mary (W&M), and Longwood University (LU). Data sources span two time periods: May 2020 …

Pursuer Evader Surveillance Game Control Theory And Motion Planning, Zijie Mu

Honors Theses

This thesis studies the pursuer evader surveillance game with a triangular obstacle in the short-term. In the game, the pursuer aims to maintain surveillance of the evader as long as possible while the evader aims to break surveillance in a finite time. We classify the player strategies into ideal ones and best admissible ones. The outcome of the game is determined by line of sight. We reduce the 4D game to a 3D game with an upward motion for a small time interval to terminate the game. When the evader starts outside the threshold, we show that there exists an …

Crafting The “Greatest Classics” Of Girlhood: Advice Columns, Diaries, And The Emotional Lives Of American Teenage Girls, 1918-1939, Kylee Violet King

Honors Theses

“Crafting the ‘Greatest Classics’ of Girlhood: Advice Columns, Diaries, and the Emotional Lives of American Teenage Girls, 1918-1939” explores how American teenage girls who came of age between 1918 and 1939 used writing as a form of expression. As a response to the heightened anxieties—the “storm and the stress”—that was caused by the social structure of the era, teenage girls used writing in advice column letters and diaries as a form of self-fashioning, self-reflection, and self-therapy to discuss courtship, dating, and romantic relationships. Additionally, depending on the medium, writing acted as a form of advice seeking and community support. Writing …

From Shock To Routine: The Evolving Impact Of Shutdown-Related Sentiment On Stock Markets, Yiran Shao

Honors Theses

To address gaps in existing research, this paper selects two U.S. government shutdown periods, 2018-2019 and 2025, as research samples to explore the effect of policy uncertainty on sentiment. This paper primarily analyzes the following two research questions.

First, what is the correlation between government shutdown-related sentiment during the shutdown period and daily market fluctuations? Specifically, can the sentiment index constructed from shutdown-related news effectively predict the next-day stock return during the event period?

Second, does the market have a learning effect? That is, between 2018-2019 and 2025, has the relationship between shutdown-related emotions and market outcomes weakened, shortened the …

Borrowing By Committee: An Analysis Of The Link Between Government Type And Sovereign Debt, René Polanco

Honors Theses

Previous literature is divided about the impact of democracy on sovereign debt. In the context of the third wave of autocratization (Lührmann & Lindberg, 2019), this paper uses a new dataset (the Episodes of Regime Transformation) focused on regime transitions to analyze the impact of democracy and regime change on the levels of sovereign debt for a panel of 167 nations between 2008 and 2024. I examine how democracy impacts debt level, borrowing, and debt service and dovetail these results with analogous ones regarding how states of transition impact the same measures. By including this extra wrinkle of government transition, …

Formal Vs. Informal Disclosure Of Campus Sexual Assault: Social Reactions, Institutional Responses, And Associated Posttraumatic Stress, Karyna Fowler

Honors Theses

With research demonstrating increasing rates of sexual victimization on college campuses (Koss et al., 1987; Koss et al., 2022), sexual assault disclosure has become a critical construct with implications for victim-survivors’ posttraumatic stress (PTS) and healing. In the present mixed-methods study, college students (N = 558) at Bucknell University completed a survey assessing sexual victimization, disclosure, peer responses, institutional betrayal and support, and PTS; a subset (n = 9) participated in qualitative interviews examining social reactions, barriers to disclosure, and present functioning. Consistent with hypotheses, women reported significantly higher rates of sexual victimization than men; disclosure was relatively infrequent (26.5%) …

Sangha: Displacement And Memory In Nikkei Dena, Isabella Rae Uriu

Honors Theses

Sangha: Displacement and Memory in Nikkei Dena explores how layered displacements have shaped the Nikkei (Japanese-American) community in Altadena and Pasadena (Dena), CA, and how Nikkei resist forces of displacement and ‘unbelonging’ through cultural practice, community care, and memory-work at the Pasadena Buddhist Temple. This thesis argues that these practices of place-making build belonging and sustain the Nikkei community across displacement; particularly, the forced removal and incarceration of people of Japanese ancestry during World War II, freeway displacement during the mid-century, and most recently, the 2025 Eaton Fire, which has displaced tens of thousands of Denans, including a small, but …

A Psychometric Evaluation Of Obsessive-Compulsive Items In The Hierarchical Taxonomy Of Psychopathology (Hitop)-Self Report Among Caregivers Of Children, Zach Wasserman

Honors Theses

Introduction: The classification and assessment of psychopathology is a crucial part of understanding mental health. The current model, published in the Diagnostic and Statistical Manual of Mental Disorders, with the current 5th edition (DSM-5; American Psychiatric Association, 2022), utilizes a categorical approach to psychopathology (i.e., one has the disorder or they do not). This creates ~300 diagnoses that are understood as theoretically distinct from one another. In reality, categorical diagnoses are often heavily comorbid (Forbes et al., 2024) and within a diagnostic category there are large amounts of heterogeneity (Feczko & Fair, 2020). To address these issues, dimensional models …

An Analysis Of Volcanic Lightning And Its Controlling Factors, Nathan Stamford

Honors Theses

Volcanic lightning, first documented during the 79 AD eruption of Mount Vesuvius, includes any electrical discharge that is generated during a volcanic eruption rather than a thunderstorm. By analyzing individual eruptions and performing laboratory experiments, previous research has identified multiple controlling factors that influence the charging mechanisms and generation of volcanic lightning. While the previous research has made significant discoveries about the phenomenon, the exact relationship between many of these controlling factors and volcanic lightning generation has been poorly quantified. In this study, we investigate these controlling factors and show that they have a wide range of influence over volcanic …

The Divide Of Women’S Health: Systematic Thinking Of Women, Tasfia T. Howlader

Honors Theses

Women’s health has constantly been changing- from public health infrastructure to health policies, and even medical advancements. Yet, the struggles are persistent within the gaps present in women’s health. The Socio-Ecological Model (SEM) explains interactions between different levels of relationships, which result in health outcomes that vary from individual factors to environmental factors. Applying the SEM to describe health disparities can help explain how the relationships an individual has influenced their health. This project serves to exemplify these different levels while discussing the tailoring of services to the needs and the importance of populations based on their experiences. Specifically, adhering …

A Phylogenetic Analysis Of Avian-Associated Ixodes Scapularis & Implications For Lyme Disease, Nora Correiro

Honors Theses

Lyme disease, caused by the bacterium Borrelia burgdorferi and transmitted by the blacklegged tick Ixodes scapularis, is the most common vector-borne illness in the United States. Whereas Lyme disease is concentrated in the northeastern US, I. scapularis exists in the southeast as well, and the ticks in these regions generally separate into northern and southern evolutionary lineages. Although recent analyses suggest unidirectional and limited gene flow from north to south due to behavioral, ecological, and environmental barriers, the mechanisms underlying the persistence of this limited gene flow remain unclear. This study examines whether bird-mediated dispersal may facilitate south-to-north gene …