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Hyposense: Multimodal Physiologic And Voc Wearable For Early Hypoglycemia Detection, Nidhi R. Patel

Honors Theses

Hypoglycemia remains a significant safety concern for insulin-dependent individuals, especially when blood glucose declines rapidly during exercise, sleep, or periods of impaired hypoglycemia awareness. Current continuous glucose monitors and automated insulin delivery systems have helped to improve diabetes management, but these technologies primarily respond to glucose trends after they have already started and may not actually provide sufficient warning before symptoms occur. This thesis describes the development of HypoSense, a noninvasive wrist worn wearable concept that is designed to support earlier hypoglycemia risk detection through multimodal physiologic and volatile organic compound emission sensing. HypoSense combines volatile organic compounds/gas sensing with …

Learning Through Play: The Effects Of Play-Based Instruction On Literacy Development, Jherica Goodgame

Honors Theses

This thesis explores the role of play-based learning in early literacy development, emphasizing its impact on student engagement, executive functioning, and overall academic success. Drawing from research and personal experience, it argues that play is not separate from learning but a critical component of it. This thesis also highlights the benefits of play for diverse learners and examines the challenges teachers face in implementing play-based instruction. It provides numerous examples of play-based instruction practiced in a real classroom setting with 17 students who are varying from early kindergarten to late kindergarten levels. This thesis seeks to demonstrate the importance of …

Bax Activation Through The N-Terminal Bh3-Like Domains Of Vdac1 And Vdac2, Autumn A. Peters

Honors Theses

Voltage-dependent anion channels (VDACs) are central to mitochondrial function by mediating metabolite diffusion across the mitochondrial outer membrane (MOM). Two isoforms­­­­­­­­­­­,­­­­­­­­­­­­­­­­­­­­­­­­­­­­ VDACs 1 and 2, are also implicated in apoptosis based on interactions with Bcl-2 family proteins that control this process, including Bax and Bcl-xL. Activation of the pro-apoptotic protein Bax by interaction with ‘BH3-only’ proteins, such as Bim or Bid, induces MOM permeabilization to signal apoptosis, yet accumulating evidence indicates VDACs 1 and 2 may also affect Bax. We discovered that the VDAC N-terminal domains contain high sequence similarity to the conserved BH3 domains within Bcl-2 family members that …

The Design And Optimization Of A Styrene Production Plant, Kaylee Hardenstein, Amanda Anderson

Honors Theses

This thesis presents the design and economic optimization of a Styrene Production Plant targeting a capacity of 100,000 tonnes/yr at a product purity of 99.8 wt%. The process relies on the dehydrogenation of ethylbenzene in a packed-bed reactor system. Downstream separation is achieved through a series of cooling, phase separation, and distillation operations to recover styrene while recycling unreacted ethylbenzene and recovering valuable byproducts.

A base case design was developed and evaluated using a process simulation software, Aspen Plus V14, and an economic analysis. Sensitivity analysis identified the styrene market price and ethylbenzene raw material cost as the dominant factors …

Impacts Of Salinity On Microbial Enzyme Activity In Coastal Waters, Natali Ariyoshi

Honors Theses

Microbial extracellular enzymes are critical for the breakdown of organic matter and nutrient cycling in aquatic ecosystems. Extracellular enzyme activity serves as an indicator of nutrient turnover rates, metabolic states, and nutrient limitations within an ecosystem. Coastal ecosystems are especially dynamic as the influx of freshwater from inland runoff or seawater intrusion from storm surges can lead to fluctuations in salinity which can restructure microbial communities and alter enzymatic activity. Despite the ecological significance of these changes, few studies have explored the effects of short-term salinity shifts on microbial extracellular enzyme activity in coastal waters. This study investigated the effects …

A Survey Of Lichen Native To Three Of Mississippi’S National Forests, William S. Granberry Iii

Honors Theses

Lichens are a major part of the environment for telling the air quality and the impact humans have on the environment. These signs go into how many species of lichen are present in a general area, and there has been a lack of a list of lichens that call Mississippi their home. The goal of this research is to help create this list through a survey of lichen in three of Mississippi’s National Forests: DeSoto, Homochitto, and Holly Springs. These three forests are ideal because they cover differing ecosystems and are in different parts of the state, heightening the chance …

Functionalized Nanodiamonds As Binding Platforms For Single-Stranded Dna, Mallory A. Chapman

Honors Theses

Nanodiamonds (NDs) offer a promising platform for biomolecular applications due to their stability, biocompatibility, and three-dimensional structure. This study focused on developing a nanodiamond–DNA complex in which streptavidin-functionalized NDs would form a protective shell around biotinylated single-stranded DNA (ssDNA), creating a core–shell system like an “M&M” candy with DNA at the center and a protective coating on the outside. DNA has many uses in nanotechnology, including DNA origami, nanomachines, and drug delivery systems, but its degradation limits its practical use, making protective strategies essential.

ND–DNA conjugates were prepared using biotin–streptavidin interactions and analyzed using gel electrophoresis. Initial separation on agarose …

Inside The World Of Probation Officers: Challenges, Perspectives, And Purpose, Achilles A.C. Beumel

Honors Theses

In the United States, probation is the most commonly imposed criminal sentence, necessitating an abundance of probation officers (POs) to serve the system. Given high rates of failed reentry in tandem with high rates of recidivism, there have been calls for a reevaluation of post-conviction supervision systems and strategies, including the PO. The PO is the final form of assistance provided by the criminal justice system to those facing reentry and can heavily impact a client’s likelihood of recidivism. Despite years of research and attempted reform, more studies are still needed to determine strategies for successful reentry outcomes. This study …

Brachial Macroparasite Loads In Estuarine Young-Of-Year Striped Mullet (Mugil Cephalus), Triston Rice

Honors Theses

Climate change is a growing threat to marine habitats globally. One ecological impact that warming water temperatures poses is the increased metabolic rate of many parasite species. Their promoted reproductive and feeding rates could pose a threat to the stability of many host populations. Parasites of the gills, or brachial parasites, are especially concerning to fish populations globally. As parasitism is not limited to a specific taxon and comprises a large diversity of ecomorphs and behaviors, geographically distinct areas may be differentially affected by the changing prevalence of parasites. This study aimed to survey current brachial parasite abundance and prevalence …

Neuroprotective Effects Of Estradiol And Genistein And Interactions With Aromatase Inhibitions Post Cerebellar Lesion In Male Zebra Finches, Grace E. Thompson, Anthony P. Irovic

Honors Theses

Across vertebrates, peripheral and brain-derived estradiol (E₂) promotes neuroplasticity. After injury, E₂ can be derived locally from testosterone via aromatase (AROM), an enzyme that is upregulated in glia at the site of neural injury. E₂disrupts testicular function and elevates cancer and stroke risk, primarily via binding to estrogen receptor alpha (ER α). Genistein (GEN), a phytoestrogen, is similar to E₂ but binds preferentially to estrogen receptor beta (ER β). It may offer neuroprotection without adverse effects of E₂. We used adult male zebra finches (ZF) to model neuroprotective effects of E_{2 …}

Barriers And Opportunities In Women-Led Dental Entrepreneurship, Eliza Grace Ulmer

Honors Theses

Barriers and Opportunities in Women-Led Dental Entrepreneurship

This research examines the barriers that women encounter when attempting to open their own business. Specifically, this research will concentrate in the dental field and health care industry. Attaining the education, skills, knowledge and criteria to become a licensed dentist is extremely difficult. Adding the licensed dentist opening their own practice adds another layer of difficulty. These challenges are further compounded when the practitioner is a woman.

This research interviewed women dentists in the business as well as entrepreneurs that opened their own health practice. These interviews showed the process and requirements needed …

Listen To Your Parents: An Exploration Into Why Mississippi Foster Parents Enter, Stay In, And Exit The System, Howell D. Jenkins Iii

Honors Theses

Like many states across the country, Mississippi’s foster care system has faced a shrinking pool of foster parents to care for the state’s most vulnerable children. When states do not have adequate numbers of foster parents, children are susceptible to negative outcomes such as developmental delays, broken attachments with adults, and extended stays in the system. This thesis seeks to understand what motivates individuals to become foster parents, how they experience the system, and what pressures influence their decision to remain fostering or close their doors. To place this research within the appropriate contexts, the thesis draws on literature from …

Community Composition Of Antibiotic-Resistant Bacteria On The Mississippi Gulf Coast, Marisa Martin, Colin Jackson

Honors Theses

The Mississippi Gulf Coast is an important resource for transportation, economic development, and recreation. Given its economic and cultural importance, it is crucial to maintain clean and safe conditions along the coast for public health, but other than routine beach monitoring, few studies have examined microbial contamination of coastal waters in this region. This study aimed to determine the quantity, composition, and distribution of bacteria resistant to six different antibiotics (Vancomycin, Kanamycin, Tetracycline, Ciprofloxacin, Erythromycin, or Amoxicillin) in seawater at seven public beaches along the Mississippi Gulf Coast. No bacteria resistant to Ciprofloxacin were detected, and bacteria resistant to Kanamycin …

Lifestyle And Activity Patterns Of The Classic Period Maya From Chac Balam And San Juan, Ambergris Caye, Belize, Abigail L. Hornbeck

Honors Theses

Bioarchaeological research often uses skeletal remains to reconstruct patterns of activity and labor in past populations. This study examines potential sex-based differences in long bone morphology among individuals from the Classic Maya sites of Chac Balam and San Juan on Ambergris Caye, Belize. These coastal communities participated in maritime trade networks, and daily activities such as cargo transport, canoe travel, and fishing may have placed distinctive mechanical stresses on the skeleton. The goal of this study was to evaluate whether measurable differences in bone structure between males and females reflect differences in habitual activity patterns.

Two complementary methods were used …

The Associations Between Problematic Social Media Use, Social Media Appearance Preoccupation, And Sleep Quality Among Emerging Adults, Lily Gisclair

Honors Theses

Emerging adulthood is a critical developmental window in which significant transitions increase vulnerability to mental health challenges. Additionally, emerging adults are spending large amounts of time on social media sites. Recent literature suggests that problematic social media use and social media appearance preoccupation could all play a role in increased anxiety, depression, and poorer sleep outcomes in young people. However, to our knowledge, few studies have directly examined the associations among all of these variables specifically in the emerging adult population. The current study was designed to examine these associations among 178 emerging adults between the ages of 18 and …

Biochemical Characterization Of Luciferase In Omphalotus Olearius, James H. Martin

Honors Theses

The overall goal of this thesis was to investigate the genetic basis of bioluminescence in Omphalotus olearius, a bioluminescent mushroom. The project initially focused on growing fungal cultures under controlled laboratory conditions and using molecular techniques such as DNA extraction, PCR, and gel electrophoresis to identify the organism and isolate the gene responsible for light production. The main objective was to insert this gene into a bacterial system to confirm its function through observable bioluminescence. However, repeated difficulties in maintaining viable fungal cultures and errors in molecular procedures resulted in inconclusive results, preventing successful gene identification. Due to these …

Ectomycorrhizal Fungal Identity Strongly Influences Soil Properties Relative To Pine Presence And Soil History In A Pine–Eucalyptus System, Braedan Watters

Honors Theses

Invasive Pinus radiata has increasingly spread into native ecosystems in the Southern Hemisphere, including Eucalyptus forests in Australia, where it forms novel hybrid forest systems in which invasive and native tree species coexist. The success of these invasions is closely tied to ectomycorrhizal fungi (EMF) such as Rhizopogon spp., yet the relative roles of pines versus their fungal symbionts in altering soil properties remain poorly understood. This study investigated the independent and interactive effects of soil history (Pinus or Eucalyptus), EMF identity, and pine presence on soil properties using a controlled factorial experiment. Soil from beneath either Pinus …

Beyond The Bug: How The Covid-19 Pandemic Exposed Longstanding Systemic Failures In The United States Workforce And Economy, Abbey M. Markley

Honors Theses

The purpose of this thesis is to investigate and discuss how longstanding systemic failures in the United States exacerbated the effects the COVID-19 pandemic had on the American economy, essential healthcare workers, and overall public trust in institutions. A review of the existing literature surrounding this topic and the subsequent results of various studies were used to compose this thesis. The United States has a painful lack of worker protections and tends to view members of its workforce as expendable, even in times such as pandemic when they are deemed essential. Healthcare workers in particular faced increasing threats to their …

Determining The Relatedness Of Simian Varicella Virus Strains Using Polymerase Chain Reactions And Delta Herpesvirus-Dervied Primers, Ellyn M. Waits

Honors Theses

This study examines genetic variation among strains of Simian Varicella Virus (SVV) using genomic analysis. The primary goal of this experiment was to observe potential genomic differences among the Liverpool vervet virus (LVV), the Tsukuba herpesvirus, and the Delta herpesvirus (DHV) strains using primer sets developed from the fully sequenced DHV strain. SVV strains were initially cultivated in Vero cell cultures to begin viral propagation. Viral proliferation in these cell cultures enables DNA isolation via standard purification methods. The extracted viral DNA is subjected to polymerase chain reaction (PCR) amplification targeting specific regions of open reading frames (ORFs) in the …

Antibiotic Resistance Patterns In Bacterial Isolates From Mississippi Gulf Coastal Environments, Lawler F. Horn

Honors Theses

Coastal environments host diverse microbial communities that play essential ecological roles but may also serve as reservoirs for antibiotic-resistant bacteria. This study investigated patterns of antibiotic resistance in microbial isolates collected from public beaches along the Mississippi Gulf Coast. A total of 143 bacterial isolates exhibited growth and were included in antibiotic susceptibility screening. High levels of antibiotic resistance were observed, with 137 of 143 isolates showing growth on vancomycin, 124 on amoxicillin, and 102 on erythromycin. Resistance to kanamycin (19/143 isolates) and tetracycline (33/143) was less common. Multidrug resistance was widespread, with 101 isolates (70.6%) resistant to three or …

Belonging, Participation, And Student Success: Evaluating The Academic Impact Of The Biology Mentor Program At The University Of Mississippi, Cole B. Davidson

Honors Theses

This thesis examines whether students’ sense of belonging within the biology department and their participation in the University of Mississippi Biology Mentor Program are associated with success in introductory biology. The project used de-identified departmental survey data and program records collected across multiple semesters in the broader archive from fall 2020 through spring 2025. For the final analyses, course outcome records, mentor attendance records, and survey based belonging records were merged by student code and semester. After removing nonbinary outcome labels and retaining cases with usable belonging data, the analytic sample included 4,299 student-semester records. The primary outcome was a …

Synthesis Of Novel Tetrafluorinated Alcohols Through The Dimerization Of Difluoromethyl Ketones For Use In Drug Development, Abigail A. Ryan

Honors Theses

As the most electronegative element, fluorine has unique applications and properties. The carbon-fluorine bond is known to be one of the strongest bonds in organic chemistry. As a result of fluorine’s high C–F bond strength, fluorine chemistry has become an interdisciplinary field of chemistry, pharmacy, physics, geology, and ecology. In pharmaceuticals for example, current estimates indicate that about 15–20% of FDA approved small-molecule drugs include at least one fluorine atom. The incorporation of fluorine atoms into organic molecules has become a powerful strategy in modern drug development, as fluorination can enhance metabolic stability, lipophilicity, and biological activity. Despite these advantages, …

Seasonal Variation And Size Distribution Of Particulate Matter In The Mississippi Delta: Implications For Source Attribution, Abigail E. Barnett

Honors Theses

This study examines seasonal patterns of particulate matter in the Mississippi Delta using data from PurpleAir sensors, with a focus on particle size distributions across PM₁.₀, PM₂.₅, and PM₁₀. The purpose of this research is to evaluate whether particulate trends in the region reflect signatures consistent with wildfire smoke or are better explained by local environmental and agricultural factors.

Daily average concentrations were analyzed and grouped by season to compare spring and summer conditions. Results show that all particle size fractions increased from spring to summer. However, PM₁₀ concentrations remained consistently higher than PM₂.₅ in both seasons. The PM₂.₅/PM₁₀ ratio …

A.I. And Education: The Relationship Between Policy And A.I. Implementation In Louisiana K-12 Schools, Johnny R. Moore Jr

Honors Theses

This research focuses on A.I. policies in Louisiana K-12 education, trying to figure out what the best possible policies would be to ensure that students are using A.I. as a tool rather than a crutch to rely on. This goes through the history and background of technology implementation and educational policies in Louisiana. The research focuses on current A.I. policies in the state, if any, and then evaluates other states policies around the country. Teachers and administrators from around the state were surveyed on this and were also asked on their opinions on A.I. in the classroom.

Quantifying Genetic Diversity In Nematode Feeding Rate, Jacob King

Honors Theses

Understanding how populations persist under changing environmental conditions is a central question in ecology and evolutionary biology. Variation in traits related to resource acquisition may play a key role in determining population survival when resources are limited or fluctuate over time. In this study, I investigated how variation in feeding-related traits influences population persistence using a combination of computational modeling and laboratory experiments. I developed a stochastic, individual-based consumer–resource model to simulate population dynamics across varying levels of trait variance and resource regimes. Across 60,000 simulated populations, increased trait variation consistently reduced extinction risk and extended persistence time, although the …

Not An Afterthought: Addressing The Academic And Social Challenges That Create Barriers To Belonging For Transfer Students, Brooke Jankowsky

Honors Theses

This thesis examines the academic and social barriers to belonging for transfer students at four-year institutions, with particular attention to the University of Mississippi. The goal is to bring attention to the issues that surround transfer student populations in general by identifying some of the most pressing structural and interpersonal challenges that shape their experiences. A qualitative approach was used, drawing on existing literature, prior unpublished research at the community college level, and reflective analysis to explore themes such as transfer shock, creating and maintaining social networks, and gaps in institutional support. Findings suggest that transfer students often face a …

The Effects Of Mississippi Mandated Testing On Students And Teachers, Christopher I. Goss

Honors Theses

This thesis concerns the direct impacts of the Mississippi mandated standardized testing, used for graduation, on Mississippi public school teachers and students. To collect appropriate data, I used the Qualtrics survey platform to fit in the parameters needed for IRB approval. This survey provided individuals an opportunity to express their opinions on certain statements, ideas, and beliefs about the current mandated standardized testing system, while also collecting background information for comparing data such as differences between how much someone from a D ranked school would support standardized testing compared to someone from an A ranked school. Most teachers and faculty …

The Mystery Of The Epstein-Barr Virus: How To Detect An Undetectable Virus, Paris Lange

Honors Theses

The Epstein-Barr Virus (EBV) is a latent virus that stays in the body after the initial acute infection. In severe cases, this virus can lead to viral myocarditis and can cause life-threatening health issues. One reason this virus is impactful is its ability to suppress the intrinsic apoptotic response through a gene called BHRF1. This gene is an early lytic gene that encodes a homolog of a human pro-survival protein named Bcl-2. This allows the gene to act as an anti-apoptotic survival factor, facilitating the viral persistence inside the host without premature death of the host’s cells. Here, the BHRF1 …

Descriptive Analysis: Effects Of Insufficient Sleep Among College Students Ages 18-22, Divine Ighalo

Honors Theses

Background: Not getting enough sleep is common among college students and is often linked to habits such as screen time, caffeine intake, stress, and irregular routines. This study examined how these lifestyle factors are associated with insufficient sleep among college students ages 18-22 and how poor sleep affects their overall wellbeing. Methods: This study used a cross-sectional survey design and collected data through an anonymous 25 question online Qualtrics questionnaire. This was completed by 150 participants. The survey was designed to be completed in about 5-7 minutes. It included a mix of multiplechoice questions, frequency-based responses and select all that …

From Crops To Kilowatts: The Growing Energy Potential Of Modern Agriculture, Karlee M. Crowe

Honors Theses

Agriculture has traditionally been defined as merely the production of food, fiber, and raw materials. Growing global challenges such as rising energy demand, resource depletion, and environmental degradation are reshaping the agricultural industry. This paper argues that modern agriculture has the potential to expand beyond its conventional roles by integrating renewable energy production—specifically through agrivoltaics and biomass generation—into existing agricultural practices. By focusing on these two main systems, this study highlights how the agriculture industry can implement energy production into already existing practices. Drawing on scientific literature and government sources, this study analyzes the environmental, economic, and social implications of …