Digital Commons Network^™

Exploring The Potential Of Martian Agriculture: Assessing Viability And Nutritional Composition Of Plants Cultivated In Martian Regolith, Abigail Ross

Honors Theses

In addition to sunlight and water, plants can utilize a small number of nutrients from the soil to biosynthesize all the materials that are needed for growth and development. However, plants require an environment where they are able to obtain those nutrients, such as iron, magnesium, potassium, sulfur, and nitrogen. Environmental factors determine the types and accessibility of nutrients available to plants. Plants then take up these nutrients from the soil to aid in biological mechanisms and the synthesis of important molecules needed for growth and development. Ascorbic acid, commonly known as Vitamin C, is a vital molecule that is …

Redefining Resistance: Las Madres De La Plaza De Mayo, Echoes Of Trauma And Memory In Argentina, Elizabeth J. Kaye

Honors Theses

Argentina's "Dirty War" (1976–1983) stands as one of the darkest and most painful periods in the nation’s history. During these years, the military dictatorship, known as the "Proceso de Reorganización Nacional," implemented a systematic campaign of state terrorism, targeting suspected political protesters, activists, intellectuals, and ordinary citizens. Widespread kidnappings, illegal detentions, and forced disappearances became routine, with an estimated 30,000 people vanishing without a trace. Families were left in despair, searching for answers that the government refused to provide. In response, a group of determined mothers, known as “Las Madres de la Plaza de Mayo”, formed a powerful movement demanding …

Investigating The Mechanisms By Which Gut Microbiome Dysbiosis Contributes To The Autoimmune Response In Multiple Sclerosis, Abigail Houtrouw

Honors Theses

This literature review explores the multifaceted relationship between gut microbiome (GM) dysbiosis and multiple sclerosis (MS), highlighting key themes that advance understanding of disease pathogenesis and therapeutic potential for treatments targeting the gut. The review underscores the immune system dysregulation in MS, emphasizing the roles of T cells, B cells, and microglia in neuroinflammation and demyelination. Historically, MS pathogenesis was thought to be driven mainly by T-cell dysregulation, but current research highlights the additional roles of B-cells and microglia, the resident immune cells of the central nervous system (CNS). Additionally, this literature review identifies GM alterations and dysbiosis as critical …

Synthesis Of Antibody Functionalized Polyaniline/Polystyrene/N-Gqds Composite Fibermats For Sweat Based Cortisol Biosensing Applications, Ashwin James

Honors Theses

Noninvasive, wearable biosensors capable of detecting stress biomarkers in sweat require electrodes that are flexible, conductive, insoluble in water, and highly sensitive at low concentrations of analyte. In this work, bovine serum albumin blocked and anti-cmab immobilized nitrogen doped graphene quantum dots integrated polyaniline/polystyrene composite fibermat electrodes (BSA/Anti-Cmab/N-GQDs/PANI/PS electrodes) were synthesized and evaluated as a potential platform for an electrochemical cortisol biosensor in sweat based systems. Polyaniline was utilized in order to provide electrical conductivity, while polystyrene served as a carrying polymer for mechanical support and its hydrophobicity. Composite fibermats were manufactured through Forcespinning™, followed by a secondary polyaniline graft …

Exploring The Relationship Between Exercise, Social Support, And Mental Health, Emma Anderson

Honors Theses

This study explored the relationship between exercise, social support, and mental health in college students. Mental health issues such as depression, anxiety, and stress are prevalent among college students. The two components that are experimented with for their potential in decreasing the effects of negative mental health are exercise and social support. This project executed a cross-sectional design by surveying three groups of college students: cycle class participants, independent exercisers, and non-active students. The recruitment process for the three groups of participants were key in measuring the physical activity levels. The participants were individually asked if they completed a specific …

Losing Control: Evaluative Access And The Limits Of Attributability In Angela Smith’S Theory Of Moral Responsibility, Henry Kissam

Honors Theses

The unwilling addict agent archetype–who wholeheartedly resolves to abstain from taking a drug but takes it regardless–is important to moral responsibility theorists for many reasons, but two in particular stand head-and-shoulders above the rest. The first is the frequency with which the archetype must be reckoned with through our everyday practices of moral assessment. It is not an idle thought experiment, pushing nothing but the theoretical limits of a particular theory. It is a near-ubiquitous presence in real, practical moral assessment. The second reason is a consequence of the first. Because we deal with the archetype frequently, we morally assess …

Identifying Barriers For Community Pharmacies As Vaccines For Children (Vfc) Providers In Rural Alabama: Opportunities For Solutions, Myra Bajwa

Honors Theses

Significant Human papillomavirus (HPV) vaccination disparities exist between rural and urban areas in the US. A primary contributor is low access to preventive care in rural areas. Among the most promising strategies to overcome this is increasing access through offering HPV vaccination in non-traditional, convenient health settings such as pharmacies. In rural areas, community pharmacies are trusted, convenient pillars of the community. In Alabama, community pharmacies are eligible for enrollment in the Vaccines for Children (VFC) Program, a federally-funded program that provides free vaccines to children and adolescents under 18 years old who are uninsured, underinsured, American Indian, or Alaska …

Analyzing The Impact Of Diet On Dusky Gopher Frog (Lithobates Sevosus) Development In Head Start Programs, Mckalyn Nelson

Honors Theses

Species are constantly impacted by human activity, directly or indirectly. One critically endangered species under investigation is the dusky gopher frog (Lithobates sevosus), which is an endemic species of frog found in the southeastern United States. Historically found from Louisiana to Alabama, a drought in 2002 narrowed the dusky gopher frog range even further. Head start programs have been shown to be effective in increasing population numbers; however, there is not much published data on the effectiveness of captive rearing diets for these programs. The dusky gopher frog head start program at the University of Southern Mississippi’s Lake …

Near-Infrared-Spectroscopy-Derived Oxygen Desaturation Rates During Post-Exercise Circulatory Occlusion As Predictors Of Cardiorespiratory Fitness Markers, Carstell Lee

Honors Theses

Cardiorespiratory fitness, measured as maximal oxygen consumption (VO₂max) is a critical predictor of all-cause mortality and overall cardiovascular health. Metabolic carts are the current gold standard for evaluation of VO₂max, but are inaccessible to most facilities and individuals, and are expensive ($20,000+). Near-Infrared spectroscopy (NIRS) has emerged as an accessible and affordable ($5,000-$10,000) alternative for evaluating skeletal muscle oxygenation kinetics and mitochondrial oxidative capacity. However, there is limited research in examining whether NIRS-derived oxygen desaturation rates can be a predictor of cardiorespiratory fitness markers (such as VO₂max and peak power output [PPO]), and whether these measurements show a superior predictive …

Expression, Purification And Characterization Of Full Length Tdp-43, Danya Abouzaid

Honors Theses

TAR DNA-binding protein 43 (TDP-43) is a 43 kDa RNA-binding protein linked to several neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and Alzheimer’s disease. 5-7,28,30,33 Studying full-length TDP-43 has been difficult because of its intrinsic instability and tendency to aggregate.19,25,28,33,36 In this study, we focused on overcoming the difficulties to express full-length TDP-43 in E. coli recombinantly. We focused on expressing full-length TDP-43 as a fusion construct with a maltose-binding protein (MBP) to improve solubility and stability. Our strategy was to purify TDP-43-MBP fusion and make biomolecular condensates with RNA before cleaving the tag with thrombin protease. …

An Assessment Of The Relationship Between Stress And Glucose Levels In Medical Laboratory Science Students, Jayla Edwards

Honors Theses

Stress is prevalent among college students. Prolonged, unmanaged stress can affect physiological processes such as glucose metabolism. This study aimed to examine the effects of stress on glucose levels of medical laboratory science (MLS) students at the University of Southern Mississippi (USM). To achieve this, the participants’ perceived stress levels and glucose levels were measured at the beginning of the semester and during finals week, a period when college students typically experience the most stress. There were nineteen MLS students that participated. Data was collected at two phases: phase 1 at the beginning of the semester and phase 2 during …

Beyond The Classroom: The Role Of Cultural Capital In College-To-Career Transitions, Keynijah Sullivan

Honors Theses

For many college students, the transition into the workforce is shaped not only by academic knowledge, but also by access to less visible resources, often referred to as cultural capital. Research has been done in the past that discusses how cultural capital is transferred through families, its role in academic settings, and its impact on employability. However, there is a gap in research focusing on the role of cultural capital in college-to-career transitions. This study uses qualitative methods, specifically semi-structured interviews with junior and senior undergraduates at the University of Southern Mississippi. The purpose of this study is to better …

Influence Of Depressive Symptomatology On Vocal Production, Olivia Taylor

Honors Theses

Language has been widely recognized as a crucial form of social connection, providing both contextual and semantic information, including intonation, pitch, rate of speech, and pauses. As mental health conditions begin to rise while mental health providers begin to decrease, research in psychology has focused on investigating other factors that may aid in the diagnosis of mental health disorders. Research has indicated that physiological factors, including vocal production, may highlight specific shifts in speech patterns or vocal characteristics. Limited research has been conducted to investigate the possible implications for the emerging adult population, despite the group obtaining the highest prevalence …

Transcription Factors And Regulatory Proteins In The Control Of Eukaryotic Gene Expression, Maya M. Minkara

Honors Theses

Transcription factors (TFs) function as precision switches that integrate signaling inputs, chromatin state, and protein homeostasis to control gene expression. This thesis unites three interconnected research themes: (1) mechanistic studies of the ubiquitin-proteasome system (UPS) in regulating eukaryotic TFs, focusing on polymerase-associated Factor 1 (Paf1) and TATA-box binding protein-associated factor 2 (Taf2); (2) identification of biomarker genes within odor-related TF networks; and (3) integration of published undergraduate research linking molecular regulation, bioinformatics, and synthetic biology. These themes are purposefully structured so that mechanistic insight into TF control sets up network-level discovery and, in turn, motivates applied and translational directions. In …

“If He Be Mr.Hyde…I Shall Be Mr.Seek”: Crime, Surveillance, And Narrative Structure In The Strange Case Of Dr. Jekyll And Mr. Hyde, Haley N. Durrett

Honors Theses

This research seeks to situate Robert Louis Stevenson's novella, The Strange Case of Dr. Jekyll and Mr. Hyde into the historical context of the time period using 19th century criminal-typing, policing structures, and the genre of detective fiction. Focusing on the representation of the criminal, Edward Hyde, the layout of the detective novel, and narrative structure, the novel creates an implicit desire for the police, that is not fulfilled throughout the novel's unraveling.

Cultural Roots Of Eating: A Comparative Analysis Of Organic Discourse And Marketing Practices In China And The United States, Zubing (Jane) Guo

Honors Theses

This thesis examines how cultural frameworks influence the development of the organic food market and shape individual attitudes towards the label “organic” in the U.S. and China. While the popularity of organic food has increased in recent years, cognitive and behavioral reactions toward the label “organic” have differed across societies. In the U.S., healthy eating discourse aligns closely with the individualistic culture and atomistic cognitive style, highlighting the importance of salient elements such as specific nutrients or chemical use. In contrast, Chinese healthy eating discourse is based on balance and harmony, which is directly related to traditional Chinese culture of …

Investigating The Cardiovascular And Autonomic Responses To Energy Drink Consumption: The Role Of Energy And Calorie Content, Sophia Schmidt

Honors Theses

Energy drinks (EDs) are among the most consumed functional beverages, often marketed to enhance focus, alertness, and physical performance. Despite their popularity, the combined cardiovascular and autonomic effects of caffeine and sugar during exercise remain poorly understood. The purpose of this study was to examine the acute cardiovascular, metabolic, and autonomic responses to sugar-sweetened (ED-S), non-nutritive sweetened (ED-NNS), and placebo beverages during submaximal cycling in healthy young males.

Nine male participants (age 22.2 ± 2.4 yrs; BMI 26.2 ± 2.9 kg/m²) completed three experimental visits in a randomized, repeated-measures design. Each visit involved ingestion of one drink (ED-S, ED-NNS, or …

A Story Of Life Through Death: An Osteobiography Of Two Individuals From The Late Saxon Period, Isabella Ragazzi

Honors Theses

The Anglo-Saxons were the most influential inhabitants of the British Isles in the years AD 450-1066, reigning during a time marked by much warfare, pestilence, and famine. Their impact on British history is still seen through archival materials as well as the archeological and bioarchaeological records. A recent development in the field of bioarchaeology is the osteobiography, which places skeletal analysis in context of the overall culture to create the most complete interpretation of the individual and their life history. Involving both traditional bioarchaeological evaluation and isotopic analysis, this method was applied to two Anglo-Saxon skulls donated to the University …

Neural Rrp6 Depletion Drives Circrna Accumulation And Motor Impairment In Drosophila Melanogaster Neurons, Joseph Serio

Honors Theses

Circular RNAs (circRNAs) are a class of ubiquitous eukaryotic RNAs created by back splicing. These noncoding RNAs can modulate gene expression and are implicated in aging and neurodegenerative diseases. To limit the contribution of circRNAs to aging and pathobiology, it is essential to understand how turnover of these molecules is regulated, as it is not clear which enzymes are chiefly responsible for degrading circRNAs in neurons. This study evaluates the roles of ribonucleases potentially involved in neural circRNA turnover using the model fly Drosophila melanogaster. A mifepristone-activated GAL4/UAS GeneSwitch expressed RNAi transgenes and inactivated the ribonucleases. Flies were evaluated on …

Implementation And Assessment Of The Openbci Platform As An Accessible Brain- Computer Interface, Jewell Norris

Honors Theses

OpenBCI is a low-cost, open-source platform for alternative brain-computer interface (BCI) software and hardware. This thesis evaluates OpenBCI’s electroencephalogram (EEG) and electromyography (EMG) capabilities by constructing and testing a 16-channel EEG system using the Ultracortex Mark IV headset and Cyton + Daisy biosensing board. The viability of the system was assessed through real-time BCI control and comparison to a clinical-grade EEG system. Real-time BCI control of an online falling-block game was tested via the use of eye blinks EMG (channels Fp1/Fp2) and head-tilt accelerometer inputs. The BCI game demonstrated reliable control despite minor latency and artifact sensitivity. For clinical comparison, …

The Inner Workings Of The Flipped Classroom, Kimberly Y. Resendiz

Honors Theses

This paper will be exploring what a flipped classroom is; specifically how teachers use the flipped classroom. First, it is important to note that the flipped classroom is a relatively new method that has popped up as early as the early 2000s. In general, this method allows for teachers to switch the environments in which learning the concepts and doing an activity are switched. The purpose of this paper is to explore the implementation of the four pillars of the flipped classroom, as well as the benefits and challenges STEM teachers face when using flipped classrooms. I have collected data …

Postmortem Vitreous Humor As An Alternative Matrix To Peripheral Blood For Benzodiazepine Detection, Sara Bussey

Honors Theses

Benzodiazepines are commonly prescribed secondary drugs of abuse that cause Central Nervous System depression through the neurotransmitter gamma aminobutyric acid. While not commonly fatal on their own, benzodiazepines have a minor risk for physical dependence and abuse. They also can have cumulative effects with other medications that can lead to overdose situations; thus, they are considered secondary drugs of abuse. While peripheral blood is considered the standard for xenobiotic detection in postmortem forensic toxicology, it is important to consider the validity of alternative matrices that could be analyzed in the event that blood was not available due to circumstances like …

Level Up: How Video Games Can Be Beneficial And Spark Creative Imagination In Players, Makendra M. Phipps

Honors Theses

Since the 2010’s, a technological trend has been flourishing: the development and enhancement of video games across different platforms. The early 1970s began the evolution of video game systems, from Atari and Magnavox Odyssey (1972) to Game Boy (1989) to Nintendo Switch 2 (2025) today. Video games themselves have also evolved, from the first basic computer games of the 1950s (such as OXO and Tennis for Two), to the introduction of arcade games in the 1970s (Pong, Space Invaders, PAC-Man), to the popular video games of today (Grand Theft Auto, Minecraft, Fortnite, R.E.P.O., to name …

From Chaos To Calm: How Ferappease Shapes Calf Behavior And Eases Weaning Woes, Rinna Tarter

Honors Theses

Weaning is widely recognized as one of the most stressful practices within the beef industry, as calves are separated from their dams and must manage changes in environment, social structure, and nutrition. This process provides indicators of stress, including increased vocalizations, reduced feed intake, pacing, and a stop in weight gain. Traditional management strategies include fenceline separation, nose flaps, and abrupt separation. Some research has begun to investigate approaches that target the biological mechanisms underlying the physiological stress response. One approach involves the use of a maternal bovine appeasing substance (mBAS), a synthetic analog of pheromones produced naturally by lactating …

Double Lenses: Understanding Adhd–Autism Comorbidity Across Gender And Pathways To Intervention, Grace A. Peak

Honors Theses

Each year, the number of people diagnosed with attention deficit hyperactivity disorder (ADHD) and Autism Spectrum Disorder (ASD) rises. This rising number is due to the abundance of research done on each disorder. Because of this increase in information, many adults and children are getting a comorbid diagnosis, meaning that they are being diagnosed with both disorders at the same time. There is one catch, however; research has shown that ADHD and ASD are spectrums, meaning that they have symptoms that can range in frequency and severity while also affecting each person differently. A large portion of the research conducted …

Maternal Nutritional Status And Immune Regulation In Early Offspring Development, Caroline C. Pagan

Honors Theses

Maternal nutrition, immune function, and microbiome health work together to shape fetal development in ways that influence health across the lifespan and even into future generations. This paper synthesizes evidence from molecular biology, nutrition science, immunology, and public health to show that essential nutrients-such as omega-3 fatty acids, folate, iron, zinc, and vitamin D-directly affect fetal immune programming, neurodevelopment, placental function, and metabolic regulation. Research on the maternal microbiome further demonstrates that microbial diversity and metabolite production modify nutrient absorption, inflammatory balance, and fetal gene expression, underscoring the microbiome’s role as both a mediator and amplifier of nutritional effects. At …

Social Drivers Of Health: Shifting The Focus Of Health Indicators From The Biological Code To The Zip Code, Jenna M. Barlage

Honors Theses

This study explored how healthcare facilities in Kentucky and Ohio are adapting to the Centers for Medicare & Medicaid Services’ (CMS) 2024 mandate requiring the collection and reporting of Social Drivers of Health (SDOH) data. Through literature review and interviews with healthcare administrators responsible for SDOH screening, documentation, and reporting, the research evaluated the central hypothesis: while the mandate has expanded the amount of available SDOH data, healthcare organizations continue to face substantial financial, technological, and organizational barriers in addressing identified patient needs. Findings indicated that many facilities have broadened and standardized their screening practices, leading to clearer early trends …

The Leap Through Reality: The Connections Between Quantum Leap’S Tropes Within Natural Science, Annamarie G. Seamans

Honors Theses

Quantum Leap aired in 1989 and became known for the show's combination of science fiction tropes. The combination of switching consciousness and time travel was an uncommon method for storytelling and stood out among the many science fiction shows released in the 1980s. Time travel has been a storytelling tool for centuries and many scientists have developed theories that allow time travel to be possible in the natural world. Many of the theories developed become improbable due to causality. However, if causality is no longer maintained there are models of time travel that become more likely. Similarly, the science behind …

The Impact Of Environmental Factors On Blood Detection: Effects Of Uv And Temperature On Blood Samples, Delaney Mccarthy

Honors Theses

Biological evidence, such as blood, is one of the most important types of forensic evidence collected from crime scenes. Blood can provide valuable information that can help identify victims, perpetrators, and give insight into what transpired. However, outdoor environments leave biological samples exposed to changing and often harsh weather conditions that can compromise the evidence’s integrity. Ultraviolet (UV) light and variable temperatures are two major factors that can degrade both the physical and chemical properties of blood. This study aimed to determine the effects of UV exposure on the detection and analysis of human blood using presumptive and confirmatory serological …

Native Plants And Water Quality At Coastal Carolina University, Sarah M. Limmer

Honors Theses

Native riparian vegetation is an extremely important part of the natural world as its adaptation to  the local environment and climate offers an increased array of ecosystem services, including soil  stabilization and water filtration. Therefore, while not the only element, native plants are a key  regulator of water quality. This study used quantitative and qualitative analysis methods to  determine how the presence or lack thereof of native vegetation affects water quality in both  landscaped ponds and natural wetlands on Coastal Carolina University’s campus. It was concluded  that there is a slight correlation between the two variables, mainly being in that …