Digital Commons Network^™

Rates And Perceptions Of Covid-19 Vaccination From University Of Mississippi Students, Josie Parham

Honors Theses

The trials, tribulations and triumphs of the global COVID-19 pandemic are impacted by and are a product of behaviors that occur at the level of nations, states, cities and, ultimately, communities. In the wake of the development of safe and effective vaccines against SARS-CoV2, the virus responsible for the pandemic, the significance of the vaccine is closely linked to the number of individuals that receive the vaccine. To date, surveys have measured sizable variations in vaccination rates between nations, states, cities, and communities. Focusing on events that have transpired in one such local community, the present study (i) measured the …

Body Image Perceptions Reflected In Social Media: A Guatemalan Instagram Study, Sarah Harris

Honors Theses

Guatemala has faced a long battle with colonialism, civil war, and an ensuing, rapid urbanization. Still today, the country exhibits high levels of malnourishment while also facing an ascending obesity epidemic. This project seeks to explore how the obesity epidemic has changed body image perceptions in the region. Through the use of social media accounts on Instagram, I aim to analyze how Guatemalan influencers use their platform to explore notions of varying body image perceptions in a country where food is culturally significant, malnutrition has plagued many communities, and obesity is growing in prevalence daily. This thesis aims to answer …

Th1, Th2, And Th17 Inflammatory Pathways Predict Cardiometabolic Protein Expression In Serum Of Covid-19 Patients, James Richard Michels

Honors Theses

A predominant source of complications in SARS-CoV-2 patients arises from severe systemic inflammation contributed to by Helper T-cell associated cytokines, potentially leading to tissue damage and organ failure. The high inflammatory burden of this viral infection often results in cardiovascular comorbidities. A better understanding of the interaction between the cytokine storm and cardiovascular proteins might inform medical decisions and therapeutic approaches. We hypothesized that all major helper T-cell inflammatory pathways (Helper T 1, Helper T 2 and Helper T 17) synergistically contribute to cardiometabolic pathways in serum of COVID-19 patients, and that both of these factors correlate to COVID-19 severity. …

Ageism, Eldercare, And Healthcare: An Examination Of Growing Old In Costa Rica, Akshaya Vijayasankar

Honors Theses

The world’s aging population and the Covid-19 pandemic have revealed the high level of ageism against older adults around the globe, which has resulted in an overall decreased quality of life for elders. Societies are now faced with the challenge of creating a suitable and equitable model of care to support their aging population. Despite the recent publication of the World Health Organization's Global Report on Ageism, there is still a large gap in the literature regarding ageism. This paper addresses the issues of institutional ageism in the eldercare and healthcare sector. I argue that Costa Rica serves as a …

Measles And Migration In Colombia And Brazil: Determinants Of Differential Disease Impact Resulting From The Venezuelan Crisis, Kaylen Hisle

Honors Theses

This thesis investigates the 2018 measles outbreaks that occurred in Colombia and Brazil as a result of importation from Venezuela, seeking to uncover underlying factors contributing to significantly greater case numbers in Brazil than in Colombia. It analyzes vaccination coverage, migrant integration, and migration policy, using a mixed-methods approach to compare the two countries. Qualitative analysis of the border zones, migration policies, health systems, and progression of the outbreaks in each country reveals that geographical and socioeconomic differences at the borders, heterogeneity of vaccination coverage, timeliness of policy responses, and disease tracing capabilities could all be possible contributors to greater …

Food Insecurity In Collegiate Athletes During Covid-19, Elizabeth Swindell

Honors Theses

A study done by Georgetown University in 2019 found that one-fourth of NCAA, D1 collegiate athletes experience food insecurity. The study purpose was to examine food security levels in student athletes at a southern university and the impact of the COVID-19 pandemic on food security in these students. A survey was completed by student athletes to determine their food security levels during the 2020 academic year at the onset of the COVID-19 pandemic. The survey included questions relating to food security based on the USDA’s food insecurity module as well as questions specifically related to the impact of food security …

The Coronavirus Pandemic And Participation In The Influencer Economy, Emma Grace Richbourg

Honors Theses

The 2019 coronavirus pandemic, also referred to as the COVID-19 pandemic, altered day-to-day life and has effected the economy quite notably. The aim of this paper is to determine to what extent the COVID-19 pandemic altered consumer behavior and whether these alterations encouraged participation in the influencer economy, which represents social media influencers who create and monetize online content. In order to do so, I administered a survey to 250 respondents to evaluate the reach of influencers during the pandemic and whether social media users felt the presence of influencers was an effective marketing technique. I also conducted an analysis …

How Chinese Media Reports On Infectious Disease Emergence And Human Environmental Interactions, Kai-Shin Newman

Honors Theses

Human activity and behavior, animal consumption and exploitation, and environmental degradation all impact the planet and those living on it. Each can contribute to the creation of favorable conditions in which pathogenic transmission can easily occur, resulting in an increase in infectious disease emergence. Through the One Health concept, an understanding of how human, animal, and environmental health are connected can help reduce these conditions in which infectious diseases can emerge and spread. However, despite being an established concept, the One Health is not widely known or implemented. Even in a country, such as China, that has a large population, …

Efficacy Of Δ-9-Tetrahydrocannabinol For Hiv-Related Neuropathic Pain, Kaia Horne

Honors Theses

Despite the availability and success of antiretroviral therapeutics, ~30% of patients living with HIV experience neuropathic pain that is often intractable. The mechanisms are not known, but there is evidence to support a role for the HIV virotoxins, Tat and/or gp120, which can damage or degenerate neurons and peripheral nerves. One mechanism by which Tat and gp120 promote nerve damage involves the stimulation of proinflammatory cytokine production from immune cells which can damage or kill bystander cells. Notably, compounds found in Cannabis exert anti-inflammatory effects and many studies report HIV patients to consume more marijuana than seronegative individuals. When people …

The Efficacy Of The Covid-19 Vaccine In Mississippi, Ilyse Miriam Levy

Honors Theses

The Efficacy of The COVID-19 Vaccine in Mississippi

(Under the direction of Dr. Xin Dang)

By tracking and analyzing fifty-three weeks of COVID-19 data, this thesis analyzes the efficacy of the COVID-19 vaccine within the State of Mississippi. Over the course of these fifty-three weeks, I have also been able to calculate the confidence intervals for vaccination efficacy and the risk reduction due to vaccination by using data regarding the correlations between deaths and vaccination status, provided to me by the Mississippi Office of Epidemiology. My analysis demonstrates that the COVID-19 vaccine is effective not only in Mississippi but also …

American Goldfinches (Spinus Tristis): Changes In Behavior During Mycoplasma Gallisepticum Infection, Hetal Shingrani

Honors Theses

Animal sickness behavior is an important component of disease ecology and is essential to understanding wildlife diseases and how and where animals allocate resources for survival. This study examines sickness behaviors, the extent of conjunctivitis, and the presence of an antibody response in relation to a Mycoplasma gallisepticum (MG) respiratory infection in American goldfinches. We conducted an experimental infection of American goldfinches and recorded behavior videos, and collected blood samples, throat swabs, eye swelling, and mass data at multiple time points throughout the experiment. An ELISA-serum assay was run after the conclusion of the study to identify the presence of …

Analyzing The Survival Rate Of Clinically Pathogenic Bacteria On Occupational Therapy Devices Used During Full Hip Replacement Rehabilitation, Meredith Rippy

Honors Theses

An increasing concern of the healthcare system has been that of Healthcare-Associated Infections (HAIs). HAIs currently account for approximately 1.7 million infections and 99,000 deaths per year in United States hospitals. HAI’s (formerly called nosocomial infections) are defined as infections that develop in patients who have been in residence in a healthcare facility (i.e., in-patient clinics) for 48 hours or longer and who previously had no evidence of infection prior to admission. Consequences of HAIs include increased length of hospital stay, exposure to high frequency antibiotics, sepsis, and in unfortunate cases, death. In out-patient environments where patients are receiving rehabilitative …

Coercion Or Influence? Ethical Strategies Leaders Should Use To Increase Covid-19 Vaccination Uptake, Olivia Podber

Honors Theses

The COVID-19 pandemic, which has led to millions of cases and deaths around the world, persists, in large part, due to vaccine hesitancy. Through interrogating the harm principle and exploring ethical justifications of influence, this thesis seeks to determine justifiable strategies leaders should use to increase COVID-19 vaccination uptake. I will argue that lesser forms of coercion—such as vaccine mandates—are justifiable, in principle, but ought not to be used by agents due to concerns for liberty and trust, and the presence of less restrictive alternatives. Thus, leaders should use influence strategies to motivate behavior change from the vaccine hesitant.

The Socioeconomic & Environmental Factors Influencing Prevalence Of Zoonotic Pathogens In Rats: A Meta-Analysis, Katelyn Wing

Honors Theses

Background/Question/Methods

Global rat populations are increasing at an alarming rate across the world. In turn, this increases the risk of human-rat interactions and the potential spread of zoonotic pathogens and parasites. Rats are the second most common host of disease and can have detrimental effects in urban ecosystems. Rattus rattus and R. norvegicus are the two most abundantly distributed species of rats and are the target organism for this study. The aim of this study is to understand the connection between environmental and socioeconomic factors that influence the rate of zoonotic disease in rats. We developed two hypotheses to gain …

Patient Knowledge Of Family History Of Cardiac Events And Risk Factors: Potential For Increase In Preventative Care Of Cardiovascular Diseases, Joseph Marentette

Honors Theses

The following literature review regards the preventative care of cardiovascular disease (CVD) patients with the knowledge of familial cardiac events and personal cardiac risk factors, particularly in younger populations ranging from ages 18 to 39, and develop potential preventative care measures. CVD is preventable with early reduction of risk factors. People can lower the impact of cardiac risk factors through the modification of their current lifestyle and behavioral habits. However, this is limited to the education and motivation of the person. Primary emphasis must be placed on community education and physician-patient interactions regarding CVD and cardiac risk factors. Physicians need …

The Effects Of Covid-19 On Well-Being Of Healthcare Workers, Hannah Meissner

Honors Theses

The development of the new coronavirus disease, COVID-19, led to the spread of turmoil across the United States and further around the globe. With the virus creating uncertainty among the population, the evidence began to demonstrate that individuals could have devastating health effects, including death. Healthcare workers are among those who were on the frontlines in order to care for the infected, ultimately increasing their own chances of acquiring the virus and putting their health at risk. These workers have experienced a direct impact due to this exposure in the form of isolation, anxiety, depression, suicide, and sleep disturbances. With …

Substituent Effect Analysis Of The Synthesis Of 1-Azabicyclo[2.2.1]Heptan-2-One Using Diels-Alder Reactions, Vida Robertson

Honors Theses

No abstract provided.

Healthcare Access Barriers And Proposed Solutions For Limited English-Proficient (Lep) Latinx Patients In Southwest Michigan, Carmen Vinkemulder

Honors Theses

This research study explores the circumstances and experiences of LatinX patients with limited English proficiency (LEP) when seeking treatment in the healthcare system of Southwest Michigan, in addition to proposing solutions to better facilitate this population’s access. The terminology used in this research, LatinX, is an American English neologism used as a genderinclusive term used interchangeably with Latino/a and/or Hispanic. This research provides an overview of the current socio-political legislature and climate of the American healthcare system as it pertains to the LatinX population to spread awareness and identify the barriers existing in our current healthcare model. This study will …

Examining An Intersection Of Environmental Justice And Covid-19 Risk Assessment: A Review, Ashley Ellis

Honors Theses

This study views the risks associated with the novel coronavirus (COVID-19) as an environmental injustice issue due to the connection between existing environmental disparities and the disproportional negative impacts brought upon by the virus. The social and health determinants attributed to those environmental disparities have traditionally been evaluated as individual risk factors, an approach that fails to gauge the complexity of an environmental injustice issue. This study employs the emerging theory of intersectionality, a belief that phenomena cannot be linked to one principal cause but instead an interconnected web of influences, in order to synthesize the multitude of factors believed …

The Role Of A-Layer In Polyunsaturated Fatty Acid (Pufa)-Mediated Effects On Aeromonas Salmonicida Subsp. Salmonicida, Allen Lin

Honors Theses

Aeromonas salmonicida subsp. salmonicida is a Gram-negative bacterium that infects salmonids and non-salmonids worldwide leading to an infection known as furunculosis, which is characterized by skin lesions and hemorrhages of the fish epidermis. This infection is carried out by a A+ (virulent strain) of A. salmonicida containing an important virulent factor known as the A-layer, which is a 2D paracrystalline structure that binds to the basement membrane and functions to promote adherence to host membranes and resistance to host defense. The purpose of this study was to examine the ability of the A+ A. salmonicida to incorporate exogenous fatty acids …

Assessing The Impact Of Covid-19 Restrictions On The Perinatal Experience In Mississippi, Baylee Grimsley

Honors Theses

The purpose of this study is to assess how COVID-19 restrictions affected the perinatal experience of women in Mississippi. A flyer detailing the purpose and inclusion criteria of the study was sent via social media platforms. Five postpartum women from the Hattiesburg, Mississippi area participated in this study. Eight open-ended questions were asked in an interview format, and a seven-question demographic survey was given to each participant at the conclusion of the interview. Five restrictions related to COVID-19 were identified: visitor restrictions in the hospital, mask requirements in healthcare facilities, screening of patients upon admission to the Labor and Delivery …

The Toll Of Our New Reality: Analyzing College Students’ Health In A Pandemic & Attitudes Towards Covid-19 Vaccinations, Ciara M. Ochoa

Honors Theses

Since the beginning of March 2020, the COVID-19 pandemic has affected several populations in the United States with many different hardships. With COVID-19 came the threat of a new disease, job insecurity affecting a large amount of our population, increased financial instability, and misinformation surrounding the new COVID-19 virus, the pandemic left an overwhelming majority of the United States population feeling mentally, physically, and overall exhausted. This study focuses on the already vulnerable and often overlooked population that is college students, and the aim of this study is to better assess the physical and mental impacts of the COVID-19 pandemic …

Calibration Study Of A Bacterial Quantification Technique Using Transport Swabs And Line Inoculations On Agar Growth Medium, Seth Larue

Honors Theses

Enumeration of bacteria has been the subject of research for over a century. Some of the techniques that have been developed include viable plate counts, the most probable number assessment, and more modern molecular techniques. Many of the newer molecular-based techniques provide little or no information about the viability of the cells being counted, and are generally not quantitative. Having quantitative data for potentially pathogenic bacteria on surfaces can be very useful in many settings, particularly in healthcare facilities. Knowing the numbers of bacterial cells present on surfaces within healthcare facilities may be important to attempt to study the cause …

What’S In An Ace: The Role Of Ace2 In Covid-19’S Tissue Damaging Effects, Christian White

Honors Theses

Coronavirus disease of 2019 (COVID-19) is the disease state caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for the current pandemic. SARS-CoV-2 infects cells via the membrane bound form of angiotensin converting enzyme 2 (ACE2). Aside from its role in viral entry, the role of ACE2 in the morbidity and mortality of severe COVID-19 is often overlooked. ACE2 functions as a member of the renin-angiotensin system (RAS) by cleaving the angiotensin II into angiotensin (1-7). Angiotensin II increases inflammation, thrombosis, and inflammation, whereas angiotensin (1-7) decreases these phenomena, making ACE2 an important balancing agent. ACE2 is …

Trading Addiction: An Analysis Of Prescription And Non-Prescription Opioid Abuse, Jordan Brock, Lisa S. Middleton

Honors Theses

Opioid abuse, addiction, and overdose is a serious public health concern that has plagued the healthcare system for the last thirty years. The compiled research in the following paper explores the rise of the opioid epidemic, the implications of more recent prescription monitoring and pain management programs, the relationship between non-prescription and prescription opioids, and the current face of the epidemic, illicit opioids. Kentucky has, unfortunately, been at the forefront of this epidemic with regard to both prescription and illicit opioids. Policy reformation and preventative action must be taken into consideration in regard to the relationship between prescription and non-prescription …

Simian Varicella Virus Antibody Response In Recombinant Svv-Siv Immunized Primates, Kiser Horne

Honors Theses

Since its emergence in the early 1980’s HIV has killed approximately 32 million people, and continues to kill over half a million people every year. Significant research into potential vaccines and cures for HIV has been ongoing for decades but has been largely unsuccessful. One of the more promising technologies that is being investigated to develop an HIV vaccine is recombinant vaccine technology. The study presented in this thesis aims to use simian varicella virus (SVV) and simian immunodeficiency virus (SIV) to act as a model for recombinant vaccine development. If a recombinant SVV-SIV vaccine can be proven safe and …

Exploring Mental Health & Covid-19: How A Pandemic Could Become America's Next Mental Health Crisis, Ashley D. Shofner

Honors Theses

A pandemic can be described as an epidemic disease that has spread over a large geographical area and has become prevalent in numerous sectors of the globe. In 2020, just over 100 years since our last major pandemic, the 1918 Influenza outbreak, the global community is facing yet another threat: COVID-19. While an individual’s physical health has consistently been of concern, research has failed to adequately consider the other dimensions of health. Among these additional dimensions of health is mental health and psychosocial wellbeing.

Pandemics and emerging infectious diseases have become modern influencers of mental health patterns. By analyzing the …

Development Of Nucleic Acid Aptamers To Inhibit Bacterial Efflux Pumps, Emilie A. Moses

Honors Theses

Multidrug resistance in bacteria, defined as the ability of a bacterial strain to resist the killing effects of more than one antibiotic, represents a major threat to global healthcare. Every year in the United States, two million people are infected with a multidrug resistant strain of bacteria. According to the Center for Disease Control (CDC), out of those two million people, about 35,000 will die from their infection. Thus, these multidrug resistant diseases are considered by the CDC to be the most dangerous diseases in the world. While multidrug resistance can occur through several different mechanisms, a major contributor to …

Examining The Effects Of Exogenous Polyunsaturated Fatty Acids On The Antimicrobial Activity Of Piscidins In Vibrio Cholerae, Elizabeth Allen

Honors Theses

Antimicrobial peptides are found in all organisms and have gained notoriety in recent years for their effectiveness against a variety of pathogens. Piscidins, first isolated from the mast cells of vertebrates, comprise a family of these host defense peptides. Piscidins 1 (P1) and 3 (P3), found in sea bass and other fishes, are isoforms with different modes of action. P1 induces membrane perturbation, while P3 binds DNA to exert antibacterial activity. Each has the ability to bind Cu2+ (P1Cu and P3Cu) which dramatically impacts their antimicrobial characteristics. The purpose of this study was to investigate the activity of metallated and …

Leadership, Job Stress And Uncertainty Among Nurses During The Covid-19 Pandemic: Impacts And Implications In Lieu Of Pertinent Theoretical Constructs, Davis Woodson

Honors Theses

The purpose of this study is to determine the effect of the COVID-19 pandemic on practicing nurses in the United States. The study considered the effect of communication, self-efficacy, intolerance to uncertainty, and life satisfaction on nurses’ job satisfaction; additionally, this study considered the extent to which nurses perceived organizational response efficacy was predicted by their perceptions of communication and perceived threat susceptibility. A total of 191 nurses participated in the online survey. The study revealed that life satisfaction was positively predicted by communication, self-efficacy, and life satisfaction in multiple regression analyses. Perceived communication positively predicted perceived organizational response efficacy …