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Honors Theses

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Tendencies Of Young Adults To Receive Follow-Up Care, Abby Smith Apr 2013

Tendencies Of Young Adults To Receive Follow-Up Care, Abby Smith

Honors Theses

The following proposal outlines the planning, implementation, and follow-up regarding an organized health fair that aims to promote healthy lifestyle in a minority population. The health fair will be conducted on October 9, 2012 at Climax Scott’s Alternative High School. The populations addressed through this project include: 60 students ranging from 16-19 years of age, 30 individuals 19 years or older and 10 teachers. The health fair will be organized by three senior-level Bronson School of Nursing students: Alexandra Scheidt, Abby Smith, and Kaelyn Monroe. The thesis project committee consists of: Dr. Sally Vliem, Professor Wendy Kershner, and Professor …


What Is Your Informatics Skill Level? The Reliability Of An Informatics Competency Measurement Tool Developed From Kaminski's Assessment Tool., Xiaomeng Sun Apr 2013

What Is Your Informatics Skill Level? The Reliability Of An Informatics Competency Measurement Tool Developed From Kaminski's Assessment Tool., Xiaomeng Sun

Honors Theses

Objectives: To determine the reliability of the nursing informatics self- assessment tool which was developed and extended from Kaminski’s assessment tool among health care students. It was hypothesized that there would be no significant difference in participant responses for a test/retest survey completed by nursing students. Methods: A survey was administered (N = 25) via a test/retest methodology at Western Michigan University. Results: For the majority of the statements, there were no significant differences between test and retest responses (p>0.05). Conclusions: The study showed that the majority of the statements were reliable. Recommendations related to the study were discussed.


The Gluten-Free Diet: An Effective Treatment For Autistic Spectrum Disorders?, Susanna Zammit Apr 2013

The Gluten-Free Diet: An Effective Treatment For Autistic Spectrum Disorders?, Susanna Zammit

Honors Theses

In 2006, autism was recognized as a national problem due to a sharp increase in the prevalence of autism spectrum disorders (ASD). Characteristics of autism include impairments in the areas of social interaction, communication, and play, while demonstrating restricted or repetitive interests and activities. Children diagnosed with ASDs may also develop angry outbursts or feeding difficulties. An estimated one-third of autistic children have a gastrointestinal (GI) disorder. Theories as to why GI distress is common with autism have resulted in the research of different therapeutic treatments. Most notably, researchers have completed studies on the gluten-free, casein-free (GFCF) diet as a …


The Future Of Geography In Health Policy : The Applicability Of The Dartmouth Atlas To Health Reform In The United States, Catherine Chase Eager Apr 2013

The Future Of Geography In Health Policy : The Applicability Of The Dartmouth Atlas To Health Reform In The United States, Catherine Chase Eager

Honors Theses

Regardless of political ideology, most policy makers agree that the United States health care system is severely flawed and significant reform is crucial.1 However, consensus ends there. Numerous reform efforts have been made over the past few decades, but the only major successful reform has been through the passage of the Patient Protection and Affordable Care Act in March 2010.2 With each reform effort there are many conflicting proposals considered and much controversy arises. The Affordable Care Act, as the law is more commonly called, is a controversial law and does not have unanimous support.3 However, to many, this landmark …


Effect Of Behavioral Intervention Training On Parents' Stress, Parenting Behaviors And Self-Efficacy, Emily Schworer Apr 2013

Effect Of Behavioral Intervention Training On Parents' Stress, Parenting Behaviors And Self-Efficacy, Emily Schworer

Honors Theses

For children with Autism Spectrum Disorders (ASDs), early intervention is incredibly important. In order for a behavioral intervention to be fully effective, it needs to be followed at all times of the day, not just during school hours. Because of this, a key factor during intervention is the involvement of parents of the child with the disorder. Parents/caregivers of children with Autism Spectrum Disorders participating in behavioral interventions at the Faison School for Autism were surveyed in order to find out more about strategies used when implementing a child’s behavioral plan at home, and also their overall understanding of the …


Adenovirus Type 5 Virions Asymmetrically Lose Icosahedral Structure At Low Phs Of Endosomes, Jennifer Marie Jarboe Apr 2013

Adenovirus Type 5 Virions Asymmetrically Lose Icosahedral Structure At Low Phs Of Endosomes, Jennifer Marie Jarboe

Honors Theses

After receptor mediated endocytosis into an endosome, human Adenovirus Type 5 (Ad5) undergoes structural changes that allow the virus to release a viral protein, pVI, that lyses the endosome and releases the virus core into the cytosol, where it travels to the nucleus to insert its genome. Structural studies of Ad5 at a range of pHs typical of endosomes (7.5-4.5) using a transmission electron microscope show that Ad5 undergoes asymmetrical loss of proteins from vertex regions at the pH of the late endosome (pH5.15). Following further acidification, Ad5 ejects core material preferentially through one vertex—indicating an asymmetry at one vertex …


Generic Medicine Price Discrimination In The Emerging Market, Amy Mcmahon Apr 2013

Generic Medicine Price Discrimination In The Emerging Market, Amy Mcmahon

Honors Theses

This paper studies price discrimination in forty emerging markets for forty-nine generic drugs for the therapeutic areas of cardiovascular diseases and infectious diseases. This paper studies how the age of a drug and how income distribution in a country affect the price discrimination of that drug in the country. Price data comes from the World Health Organization and Health Action International database. This paper shows that: (1) the longer the drug has been on the market, the less price discrimination that is present; and (2) the greater the income inequality in a country, the more price discrimination that is present. …


The Effect Of Oral Contraceptives On Performance In Sexually Dimorphic Cognitive Tasks, Kathryn Sears Apr 2013

The Effect Of Oral Contraceptives On Performance In Sexually Dimorphic Cognitive Tasks, Kathryn Sears

Honors Theses

The goal of the current study was to further extend limited research assessing the effects of sex, menstrual phase, and oral contraceptive use on sexually dimorphic cognitive tasks, as well as emotional regulation. Studies have found that menstrual cycle phases have cognitive and physiological effects on women’s brains depending on the concentration of female sex hormones, progesterone and estrogen (Epting & Overman, 1998). Oral Contraceptive pills (OC) contain a concentration of these female sex hormones that have been shown to alter gray matter volume to resemble men’s brains in areas associated with learning, memory, spatial navigation, and emotional regulation (Pletzer …


Differential Diagnosis Of Adhd And Bipolar Disorder : An Analogue Study, Sarah Yurinich Apr 2013

Differential Diagnosis Of Adhd And Bipolar Disorder : An Analogue Study, Sarah Yurinich

Honors Theses

Bipolar disorder (BD) and attention deficit/hyperactivity disorder (ADHD) share an overlapping number of symptoms. These shared symptoms may result in the misdiagnosis or over diagnosis of these two disorders. The purpose of this study was to look at the diagnostic practices of clinicians and clinicians-in-training to see what diagnosis they would give to a hypothetical patient who presents with ambiguously ADHD and bipolar disorder symptoms. Clinicians and clinicians-in-training (N = 40) read two vignettes, one child and one adult, where the patient presented with both ADHD and BD overlapping symptoms, and then were asked to provide one primary DSM-IV diagnosis, …


A Comparison Of Mindfulness And Incremental Theory Based Interventions, Kelsey Greenfield Apr 2013

A Comparison Of Mindfulness And Incremental Theory Based Interventions, Kelsey Greenfield

Honors Theses

In only a span of 20 years, the prevalence of obesity has dramatically increased in the United States. Thirty five percent of adults and seventeen percent of children are obese. Every state has an obesity prevalence of over twenty percent (CDC, 2013). The Center for Disease Control and Prevention defines obesity as having a body mass index (BMI) of 30 or greater. A person's weight and height are used to calculate BMI, which indicates level of body fatness that may lead to health problems (CDC, 2013). From the economy to healthcare, this weight trend has turned into a phenomenon that …


Curing The Obesity Epidemic : The Government's Obligation To Regulate Food, Victoria Lyon Apr 2013

Curing The Obesity Epidemic : The Government's Obligation To Regulate Food, Victoria Lyon

Honors Theses

The first chapter demonstrates the impact of the obesity epidemic in the United States. The epidemic affects obese individual directly, and burdens all US citizens. The second chapter is an argument as to why the obesity epidemic should be addressed by government intervention. The US regulates risky substances such as consumption of alcohol, tobacco, and marijuana, and risky behaviors such as driving. This work explores why food is morally equal to other risky substances. The final chapter explores several food regulation policy options.


Factors Of Cultural Perception Of Depression: An Analysis Of Students At The University Of Tennessee At Chattanooga, Rachel Brosius Mar 2013

Factors Of Cultural Perception Of Depression: An Analysis Of Students At The University Of Tennessee At Chattanooga, Rachel Brosius

Honors Theses

This study focuses on the perceptions and beliefs of a population of students from the University of Tennessee at Chattanooga toward depression and the contributing cultural factors behind its high prevalence. The study is broken into eight sections that contribute to the overall understanding of depression in Tennessee. First, the current literature on depression and stigmata related to mental illness is examined to catalogue the findings ofresearchers with similar interests. Following this the data collection methods I took to gain the data used in this study are explained as well as the demographic elements of the study. Next the data …


Following The Glory Cloud: Bethel Church & Maintenance Of The Revival Church, Jenny Edwards Mar 2013

Following The Glory Cloud: Bethel Church & Maintenance Of The Revival Church, Jenny Edwards

Honors Theses

This departmental honors project examines the effects of routinization of charisma upon Bethel Church in Redding, California. As a movement related to both the Assemblies of God and the Toronto Blessing of the 1990s, Bethel has begun to declare an eternal revival based in their city. To prevent the movement from routinizing and dissipating, the leadership has instituted several structures within the church. The overall corporate hierarchy, the recent policy of inclusion within the hierarchy regardless of gender, the involvement of the congregation in performing miraculous acts, and the discipleship of future generations of participants and leaders through established ministry …


Identification Of A Human Myofibril-Inducing Rna, Ashley Moses Feb 2013

Identification Of A Human Myofibril-Inducing Rna, Ashley Moses

Honors Theses

No abstract provided.


Treatment Of Food Selectivity In Children With Autism: A Review Of Literature And Introduction To Holistic Treatment Approach, Tara Swodzinski Jan 2013

Treatment Of Food Selectivity In Children With Autism: A Review Of Literature And Introduction To Holistic Treatment Approach, Tara Swodzinski

Honors Theses

Food selectivity is a problem in many of the lives of children with autism. Limited food repertoires can negatively affect nutritional status and the quality of life for these children and their families. The precise cause of this food selectivity is unknown although a number of reasons have been posited. This inability to pinpoint an exact cause has lead to a debate between researchers about whether behavioral or physiological issues are to blame. This paper first explores both of these options. Then, a new clinical program at WMU OT Unified Clinics is described that focuses on a holistic approach used …


White Female Criminals In Civil War Richmond, 1860-1865, Frances Sisson Jan 2013

White Female Criminals In Civil War Richmond, 1860-1865, Frances Sisson

Honors Theses

This study tells the story of white female criminals and addresses the problem of the white female criminality and the resulting reaction of the patriarchal society in Richmond, Virginia during the Civil War, specifically the years 1861-1864. During the Civil War, white female criminality became a daily occurrence because of the wartime conditions in Richmond, such as inflation and overpopulation. Because of the established patriarchal society and the lack of emphasis on the women's rights movement in the South, the female involvement in crime during the war was extremely shocking to the male driven society. The judicial system struggled with …


Investigating The Effects Of Bag3 Knockdown On The Cytotoxicity Of The Anticancer Drug Laromustine, Kayla Gross Jan 2013

Investigating The Effects Of Bag3 Knockdown On The Cytotoxicity Of The Anticancer Drug Laromustine, Kayla Gross

Honors Theses

Laromustine is a sulfonylhydrazine anticancer prodrug whose cytotoxicity results from the formation of interstrand cross-links caused by the synergistic action of co- generated 2-chloroethylating and carbamoylating species. The cytotoxic activities of Laromustine involve the induction of apoptosis. Described herein is an investigation into this drug’s effects on apoptotic gene expression in HL-60 cells using qRT-PCR. Significant changes in the expression levels of 13 genes were observed, most dramatically in the upregulation of the bcl2-associated athanogene 3 (BAG3) gene. Given the pro-survival role of BAG3 in the cell, this investigation sought to decrease BAG3 mRNA levels in HL-60 cells using transient …


Metallic Mineral Mining In Maine, Kaitlyn Bernard Jan 2013

Metallic Mineral Mining In Maine, Kaitlyn Bernard

Honors Theses

In 2012 the Maine State Legislature passed a bill directing the Maine Department of Environmental Protection (DEP) to rewrite the regulations governing metallic mineral mining in Maine. The bill was introduced after pressure from Maine’s largest private land owner and timber company, J.D. Irving, Limited. The company has a lucrative mineral deposit on one of their landholdings in northern Maine and is interested in pursuing a mining development project. The bill aimed to streamline the regulatory framework around mining operations and make the permitting process more conducive to mineral development throughout the state. The 2012 Maine Metallic Mineral Mining Act …


Development Of A Standard And Functional Tactical Emergency Medical Curriculum -- Tems Medic, Benjamin Hannon Jan 2013

Development Of A Standard And Functional Tactical Emergency Medical Curriculum -- Tems Medic, Benjamin Hannon

Honors Theses

Violent crime causes death and injury regularly in the United States. Some events such as the Newtown shootings, the Oklahoma City bombings, or the Washington, DC sniper case acutely focus the entire nation’s attention while other, less contemporary events fade away. The public safety apparatus – police, fire, and emergency medical services – always respond to save lives. On December 11, 2012 a man opened fire at a mall in Clackamas County, Oregon. The 9-1-1 dispatchers sent units to a shooting at the mall and then quickly reported that the shooter was still firing in the mall. One of the …


Aiding Or Abetting? An Analysis Of Medical Humanitarian Aid In Complex Humanitarian Emergencies, Claire Dunn Jan 2013

Aiding Or Abetting? An Analysis Of Medical Humanitarian Aid In Complex Humanitarian Emergencies, Claire Dunn

Honors Theses

Medical humanitarianism is generally viewed very positively by society. Selfless humanitarians are going to war-torn, disaster-affected, or otherwise undesirable locations to provide medical care to those who are in need. However, when considered more carefully, it becomes clear that there are many problematic aspects of humanitarian aid. That is not to say that humanitarian aid is unnecessary, but rather that humanitarian actions are likely to have some unintended consequences or fail to live up to their potential no matter how well-meaning the intentions. Acknowledging that medical humanitarianism is but a single component of the response to complex humanitarian emergencies and …


An Unexpected Verdict: Exploring The Economic Implications Of An Expanding Chinese Presence In Dakar's Informal Market, Georgina Hurst Jan 2013

An Unexpected Verdict: Exploring The Economic Implications Of An Expanding Chinese Presence In Dakar's Informal Market, Georgina Hurst

Honors Theses

Through examination of literature, statistical analysis, and field research in Dakar, Senegal, this study explores the economic implications of an expanding Chinese presence on Senegalese retailers in the informal market of Dakar, and on Senegalese consumers of cheap goods that shop primarily in this market. Since the early 1990s, a neighborhood of Chinese storefronts selling cheap goods has developed in the Centenaire region of downtown Dakar. The Chinese entrepreneurs, primarily in Dakar for wholesale, have adapted to the demands of low-end Senegalese retailers and consumers, focusing their products on basic necessities, such as clothing, and imitation commodities, such as Islamic …


Investigating The Role Of Epibiotic Bacteria In Defense Against Chytridiomycosis In The Green Frog, Lithobates Clamitans, Sarah Nalven Jan 2013

Investigating The Role Of Epibiotic Bacteria In Defense Against Chytridiomycosis In The Green Frog, Lithobates Clamitans, Sarah Nalven

Honors Theses

Amphibian populations have been declining for several decades, in part due to the emerging fungal skin disease, chytridiomycosis, caused by the chytrid fungus Batrachochytrium dendrobatidis (Bd). Chytridiomycosis has caused extinctions and extirpations in many parts of the world, but its influence varies across species, populations, and individuals. The Green Frog (Lithobates clamitans), which inhabits the eastern half of the United States, seems capable of sustaining Bd infections without experiencing die-offs. It is possible that the Green Frog's epibiotic bacteria are contributing to its defense against Bd as the epibiotic bacteria of several amphibian species are known to play …


Through The Eyes Of Urban Students: Educational Inequality And Socioeconomic Disparities In Santiago, Chile, Hillary Sapanski Jan 2013

Through The Eyes Of Urban Students: Educational Inequality And Socioeconomic Disparities In Santiago, Chile, Hillary Sapanski

Honors Theses

This project explores student perceptions of educational inequality in Santiago, Chile. Educational inequality in Santiago is statistically well documented; this study is novel in that it gives voice to the students. Despite a major emerging middle class, across all classes there is an overwhelming awareness of inequality. The results in this study are two-fold: not only do the diverse student experiences illustrate the stark divisions in the Chilean education system and society, but their experiences also demonstrate the development of a critical consciousness empowering students to act. Although there are limitations, student contributions to the ongoing conversation about inequality and …


Remapping Nature: Motherhood, Autonomy, And Anti-Mining Activism In Íntag, Ecuador, Ellicott K. Dandy Jan 2013

Remapping Nature: Motherhood, Autonomy, And Anti-Mining Activism In Íntag, Ecuador, Ellicott K. Dandy

Honors Theses

This honors thesis explores the social changes that women engaged in anti-mining activism bring to a region in rural Ecuador. I discuss the ways in which they incorporate their activist techniques into everyday life, using their status as mothers to access public discourses of environmentalism, and ultimately rewrite gender roles locally. Framing the mining conflict as a catalyst for social change, I draw parallels between this movement and indigenous politics in Ecuador, propose new interpretations of the mestizo ethnic identity and assimilation in the Spanish Empire, and finally, make the case for a nature-centric cultural analysis in anthropology.


Relationship Of Cross-Linking Potential To Mechanism Of Cell Death, Adam N. Spierer Jan 2013

Relationship Of Cross-Linking Potential To Mechanism Of Cell Death, Adam N. Spierer

Honors Theses

Mechlorethamine (HN2), a nitrogen derivative of mustard gas, was the first synthetic anti-tumor chemotherapeutic because it forms covalent cross-links between strands of duplex DNA. HN2 represents a class of bifunctional alkylating agents that are both chemotherapeutic and carcinogenic: diepoxybutane (DEB), the active form of the pro-drug treosulfan, and epichlorohydrin (ECH), a structural hybrid of HN2 and DEB, also form covalent cross-links between DNA. While HN2 and DEB are clinically used as anti-tumor chemotherapeutics, ECH is a structural hybrid of these two compounds not used in a clinical setting. Accordingly, we aimed to understand the relationship between the cross-linking potential of …


Does Exchange Market React To Central Bank Governor Replacements: Evidence From A New Dataset Using Narrative Approach, Siyang Xu Jan 2013

Does Exchange Market React To Central Bank Governor Replacements: Evidence From A New Dataset Using Narrative Approach, Siyang Xu

Honors Theses

This paper contributes to the literature that analyzes the exchange market reaction to the event of a central bank governor replacement. In order to solve the endogeneity problem, we develop a narrative approach-based on reports from credible newspapers-that classifies central bank governor replacements by their nature and causes. Using this new dataset on central bank independence for 31 countries over the period 1967-2012, we decompose all replacements into endogenous and exogenous cases with respect to inflation and financial market performance. We find that such a distinction is critical in understanding the exchange market reactions. We show that i) endogenous replacements, …


When The Confederates Terrorized Maine: The Battle Of Portland Harbor, Carter Stevens Jan 2013

When The Confederates Terrorized Maine: The Battle Of Portland Harbor, Carter Stevens

Honors Theses

Saturday, June 27, 1863, dawned brightly over Portland, Maine. As the city’s residents began to go about their weekend business, they suddenly realized that the Caleb Cushing, the United States Revenue Cutter (U.S.R.C.) which had been stationed in Portland Harbor on and off again since 1853, was missing. Rumors flew about a traitorous Southerner on board, the work of pirates on the coast, and more. Before the day was over, the revenue cutter would be destroyed and the Casco Bay area would be transformed forever, a victim of one of the northernmost events of the Civil War on the periphery. …


Finite To Fail, Infinite To Venture: Interactivism And Relational Ethics, Rachel A. Rosenbaum Jan 2013

Finite To Fail, Infinite To Venture: Interactivism And Relational Ethics, Rachel A. Rosenbaum

Honors Theses

This project tells the story of a group of anonymous activists at Colby College that I call 'The EDFC.' To tell the story of The EDFC I build a theory of activism that I call 'Interactivism as Anarchism' that reveals how certain structures and processes affect activism. My goals are to highlight the subjectivity of the members of the group, the creation of the collective, and the process of our activism in ways that reveal the broader implications that this group has on: 1) what makes activism effective, 2) what inhibits and incites activism at Colby, and 3) what does …


Precision And Accuracy: Omnipod Pdm® (O-Pdm) Versus Freestyle Lite Meter® (Fsl Meter) Utilizing Freestyle Lite (Fsl)® Test Strips In Multiple Patient Situations, Christine M. Hayden Jan 2013

Precision And Accuracy: Omnipod Pdm® (O-Pdm) Versus Freestyle Lite Meter® (Fsl Meter) Utilizing Freestyle Lite (Fsl)® Test Strips In Multiple Patient Situations, Christine M. Hayden

Honors Theses

Today, diabetes mellitus affects 8.3% of the people in the United States and is having detrimental effects on patient populations as well as health care. To this date, there are numerous monitors that all meet specific requirements and industry standards in order to aid patients in self-monitoring of blood glucose (SMBG). There is currently a large market for these monitors and efforts have been made to devise the monitors to be accurate and precise. Through this study, accuracy and precision were studied by evaluating the difference between the O-PDM and FSL meter monitoring systems. It was hypothesized that a difference …


Synthesis Of A New Scytovirin Protein Derivative, Sd1-Sd2-Sd2, To Decrease Hiv-1 Binding Affinity, Alexandra M. Wood Jan 2013

Synthesis Of A New Scytovirin Protein Derivative, Sd1-Sd2-Sd2, To Decrease Hiv-1 Binding Affinity, Alexandra M. Wood

Honors Theses

Scytovirin is a novel anti-viral protein isolated from the cyanobacterium Scytonema varium. This protein has produced great scientific interest for its anti-human immunodeficiency virus (HIV) activity. Scytovirin disrupts the mechanism of HV infection by binding to HIV-1 proteins glycoprotein 120, glycoprotein 160, and glycoprotein 41. It does not bind to the CD4 receptor on human immune cells. The wild-type protein consists of a single 95 amino acid chain. When folded, Scytovirin's amino acid sequence is arranged into two distinct domains, each with a high degree of sequence conservation. This implicates the importance of both domains in anti-HIV activity. Primers were …