Traumatic Brain Injury Induces Cerebrovascular Dysfunction: Consequences For Ischemia And Cerebral Hypoperfusion, Bailey J. Whitehead

Graduate Theses, Dissertations, and Problem Reports (ETD)

Traumatic brain injury (TBI) is a significant health concern across the United States as well as the broader globe, affecting millions of individuals on an annual basis. While most recover from their TBI and resume their lives normally, some subsets of TBI survivors continue to experience impairments and increased risk for future diseases like cardiovascular disease, stroke, and aging related disease like Alzheimer’s Disease or VCID.

TBI remains a fundamentally difficult neurological injury to pin down mechanistically, due to the variability in severity, timing, and age of patient, among other factors. One significant factor in the pathology has consistently been …

Nasals And Nasalization In Yoruba-Ijebu Dialect, Khadijat Olakintan Abdulrazaq

Graduate Theses, Dissertations, and Problem Reports (ETD)

This thesis focuses on how nasals behave in Yoruba-Ijebu Dialect (YID); YID is one of the dialects of the Yoruba language spoken in Nigeria. The main findings of the thesis are in two parts. The first part discusses local nasalization spreading in a YID CV syllable (sequence of a consonant and a vowel). Three local nasalization spreading rules (simplified to two), which are (i) Nasal spreading from an inherent nasal consonant to an adjacent oral vowel, (ii) Nasal spreading from an inherent nasal vowel to an adjacent sonorant consonant, (iii) Oral (-Nas) spreading from an obstruent to adjacent nasal vowels …

The Impact Of Normal Growth On The Ap Relationships Of The Jaws And Incisors To The Forehead: A Serial Cephalometric Analysis Of Untreated Individuals, Adam Joseph Rudmann Dr

Graduate Theses, Dissertations, and Problem Reports (ETD)

Abstract

The Impact of Normal Growth on the AP Relationships of the Jaws and Incisors to the Forehead: A Serial Cephalometric Analysis of Untreated Individuals

Adam Rudmann D.D.S. M.S.

Background and Objectives

Growth of the craniofacial complex is a critical factor to consider when treatment planning an orthodontic case. The ability to predict how the forehead and jaws will change over time depends on the ability to find predictable landmarks either radiographically or clinically, and use them to gauge the relative growth of various facial structures. This data can then be integrated with other diagnostic information such as occlusion and …

Photoinduced Alpha-Hydroxy C–H Alkylation Of Mono-Alcohols Via Hydrogen Atom Transfer (Hat) Of An Activated Boron-Containing Complex, Courtney Deanna Glenn

Graduate Theses, Dissertations, and Problem Reports (ETD)

Hydroxy (-OH) groups are one of the most abundant functional groups found in natural products and pharmaceuticals with many of these compounds containing multiple alcohol classes. The ability to selectively functionalize a specific α-OH C–H bond in the presence of other competitive sites would provide straightforward access to new, potentially bioactive compounds. In recent literature, photoredox catalysis has been implemented to perform site and stereoselective α-OH C–H functionalization of cis-diol containing substrates. Incorporating an organoboron cocatalyst into these systems have proven to be crucial in decreasing the bond dissociation energy (BDE) and increasing hydricity of the α-OH C–H bond …

E-Cigarette Aerosol’S Effect On The Force Degradation Of Elastomeric Chain: An In Vitro Study, Joshua D. Lokant

Graduate Theses, Dissertations, and Problem Reports (ETD)

Abstract

E-Cigarette Aerosol’s Effect on the Force Degradation of Elastomeric Chain: An in Vitro Study

Joshua Lokant D.D.S.

Background and Objectives

Orthodontic elastomeric chain is used in orthodontic treatment for various applications such as closing spaces, aligning teeth, correcting midlines, promoting even spaces, and retracting teeth. Ideally, this force is light, continuous, and maintains a constant force between orthodontic appointments. There are many companies that manufacture polyurethane power chain, and their proprietary formulas give rise to different force levels and constancy of force. When the power chain is in the mouth, it is subject to food, liquids, temperature changes, pH …

Exploring The Relationship Between Perfectionism And Academic Achievement In College Stem Students, Alexander Joseph Tylka

Graduate Theses, Dissertations, and Problem Reports (ETD)

Higher education practitioners and researchers in the STEM field continue seeking ways to effectively identify and understand student challenges as part of an effort to support student success, retention, and persistence. These efforts have led researchers to explore non-cognitive personality factors such as perfectionism as a way of understanding students’ thoughts, feelings, behaviors, and outcomes. This research explores two fundamental research questions regarding the ability of perfectionism to predict end-of-term GPA. First, does perfectionism predict end-of-term GPA using the 2x2 model of dispositional perfectionism? The hypotheses associated with the 2x2 model were used to address this question, and the results …

The Perceived Effects Of Peer-Assisted Learning In A Collegiate Instrumental Pedagogy Classroom, Hannah Wagoner

Graduate Theses, Dissertations, and Problem Reports (ETD)

Peer-assisted learning (PAL) is an approach that teachers can use in the classroom to increase students’ ownership of their learning. Besides increased autonomy, PAL can provide several other academic and social benefits, such as increased achievement and fostering a sense of community. This study aimed to examine the effects of PAL on college students’ performance on a secondary instrument. Five students in a collegiate instrumental pedagogy course experienced PAL activities in class while learning secondary instruments. After a statistical and content analysis of all the data, results showed that 1) all but one of the participants improved in their performance …

Rural Student Postsecondary Decision-Making: Navigating Narratives Of The Purpose And Value Of Higher Education, Ashley Renee Leggett-Bradley

Graduate Theses, Dissertations, and Problem Reports (ETD)

The narrative surrounding the purpose and place of higher education has shifted dramatically over the past few decades, despite the persistent perceptions of the necessity of an educated society. With these shifts and conflicting narratives comes the question of how students are influenced by these narratives as they make their postsecondary decisions. This study seeks to illuminate the unique way that rural students receive, understand, and are influenced by these potentially conflicting narratives through a qualitative multi-site case study. All three sites are located within the North Central Appalachian portion of the state of West Virginia, and encompass a range …

Isabella: An Eternal Badass An Actor’S Exploration On Healing, Forgiveness, And Learning To Embrace The Messiness Through Isabella In William Shakespeare’S Measure For Measure, Shelby E. Garrett

Graduate Theses, Dissertations, and Problem Reports (ETD)

This thesis not only delves into the acting methods used to portray Shakespeare's Isabella in West Virginia University's spring 2023 production of Measure for Measure, but also examines the innovative approach of interpreting the character through the perspective of an older actor. It will examine acting techniques such as Meisner, Fitzmaurice Voicework®, yoga, and chakra work, detailing their influence on character development. From audition to performance, this document will track my journey, capturing personal insights through journal entries, sound bites, and images that helped in shaping a more mature Isabella. Additionally, it explores how actors navigate personal challenges during …

Evaluating Land Cover Change And Opportunities For Bioenergy Crop Development On Surface Mine Sites In West Virginia, U.S.A., Kenzie D. Kohrs

Graduate Theses, Dissertations, and Problem Reports (ETD)

Surface mining can impact land cover, forests, and water quality. Current reclamation strategies include revegetation with herbaceous species due to the ease and speed of cover establishment. Herbaceous and woody biomass crops have been used in various studies to reclaim surface mines and act as an alternative to nonrenewable energy sources. The objectives of this study were to quantify the state of vegetation growth on former surface mines in West Virginia over a 9-year period and identify suitable acreage for bioenergy production. During 2011 to 2020, we found that over 40,000 acres had been converted to forest and 40,000 acres …

Essays On Urban Transportation And Health Economics, Alexander P. Tsiukes

Graduate Theses, Dissertations, and Problem Reports (ETD)

The first chapter analyzes how Premier League games in London impact demand for the city’s bike-sharing system. Bike-sharing systems affect mode choice for within-city transportation. Using bike rental data from Transport for London, this chapter exploits the plausibly-exogenous timing of Premier League games to identify how proximity to stadiums affects demand for London’s bike-sharing system. Results indicate games at Stamford Bridge (stadium) cause a 24.36% increase in the number of bike trips arriving within 0.5km of the stadium, with effects diminishing as distance increases. In contrast, games at London Stadium decrease nearby bike-sharing use and may actually crowd out would-be …

A Test Of The Extended Theoretical Model Of Communal Coping Among Graduate Students: Investigating The Influence Of Communal Coping On Graduate Students’ Psychological Well-Being, Rebekah M. Chiasson

Graduate Theses, Dissertations, and Problem Reports (ETD)

The purpose of this dissertation was to test the extended theoretical model of communal coping (T. Afifi et al., 2020) in a graduate student sample by exploring predictors and outcomes of communal coping processes among 554 graduate students. The extended theoretical model of communal coping specifies that communal coping occurs when individuals within a community—such as graduate students within an academic program—perceive stressors as shared and are willing to take joint action to overcome those stressors. Results of this dissertation provided evidence that graduate students’ academic stress and the severity of individual academic stressors negatively impacted their psychological well-being. The …

Impacts Of Community Food Outreach Programs On Low-Income Families: St. Ursula’S Food Outreach Program In Pursglove Monongalia, West Virginia, United States As A Case Study, Oluwafunke Abeleje

Graduate Theses, Dissertations, and Problem Reports (ETD)

ABSTRACT

Impacts Of Community Food Outreach Programs on Low-Income Families: St. Ursula’s Food Outreach Program in Pursglove Monongalia, West Virginia as A Case Study

Abeleje Oluwafunke Rebecca

According to previous research studies as stated by Fatka (2023), in 2014, 14% of households in the United States had levels of food insecurity. Also, as noted by Pitts, 2020, food insecurity rates rose across the board in the United States during the early COVID-19 epidemic and tripled among families with children. Compared to other industrialized countries, the United States had very high rates of food insecurity before the outbreak (Poblacion et al., …

Assessing The Impact Of Olive Oil And Flaxseed Oil Supplementation On Hypertension And Inflammation In Healthy And At-Risk Adults, Tara Bess Mcnabb

Graduate Theses, Dissertations, and Problem Reports (ETD)

Background: Supplementation of olive oil and flaxseed oil and their impacts on hypertension and inflammation have been reported for healthy and hypertensive adults. However, a comprehensive systematic literature review and meta-analysis on the preventive benefit of plant oil supplementation in healthy adults and adults at risk of inflammation inducing hypertension is lacking.

Objective: to evaluate human clinical trials assessing the impact of olive oil and flaxseed oil capsules on systolic blood pressure (SBP) and diastolic blood pressure (DBP) and select inflammatory markers in non-hypertensive and at-risk adults of hypertension.

Data sources: Four databases were searched in October 2023 …

The Sex Chromosome Complement And Gut Microbiome Act Independently And Collaboratively To Impart Sex Dimorphisms In Humoral Immunity, Carly J. Amato-Menker

Graduate Theses, Dissertations, and Problem Reports (ETD)

Sex dimorphisms in immunity are well-documented and have significant clinical implications. While the immunomodulatory effects of sex hormones have been extensively documented, recent recognition of the nuanced contributions of the sex chromosome complement (XX vs. XY) and the gut microbiome to immune sex dimorphisms underscores the need for a more comprehensive understanding. Within this context, the work herein focuses on unraveling the individual and collaborative impacts of the sex chromosome complement and gut microbiota on humoral immune activation. We assessed humoral immune responses to immunization with heat-killed Streptococcus pneumoniae (HKSP) in Four Core Genotype (FCG) mice and found elevated IgM-secreting …

The Influence Of Faculty Mentorship On Graduate Student Development Through The Lens Of Self-Efficacy, Connor Lynn Ferguson

Graduate Theses, Dissertations, and Problem Reports (ETD)

This exploratory sequential mixed-methods case study explores the relationship between perceived self-efficacy and faculty mentorship with biomedical sciences graduate students. The intent of the study was to understand the extent at which faculty mentorship contributes to self-efficacy development in the population of biomedical sciences doctoral students enrolled at a mid-Atlantic R1 institution. Data collected consisted of a survey assessing perceived self-efficacy and mentoring, interviews and documents. Data analysis explored themes related to the perceived academic and professional development of the students through their responses. The research highlights the significance of the mentor-mentee relationship and influence of the mentor on the …

Does It Sound Like I'M Talking?, Justin E. Borak

Graduate Theses, Dissertations, and Problem Reports (ETD)

Jean-Baptiste Poquelin, better known by his stage name, Molière, was widely known as one of the greatest writers in France. His biting satirical thoughts on French hypocrisy, as well as the brilliance in his verse, will be investigated through one of his most popular plays, The Misanthrope. Throughout these pages, I will explore this by diving into the character of Philinte, the trusted best friend of Alceste, the misanthrope, and take a deeper look into the empathetic character who is desperately trying to walk the line of truth and bootlicking. I will accomplish this by researching Molière himself, his specific …

Investigating Birds As Dispersal Vectors Of Litylenchus Crenatae Subsp. Mccannii (Anguinidae), The Nematode Associated With Beech Leaf Disease, Spencer Rock Parkinson

Graduate Theses, Dissertations, and Problem Reports (ETD)

Beech leaf disease (BLD) is an emerging forest pathogen primarily affecting American beech (Fagus grandifolia, Ehrh.) in North America and has been attributed to tree mortality of sapling sized trees within five to seven years of infection. Symptoms typically occur in regenerating American beech thickets sprouting from roots of trees killed by beech bark disease. Scientists first observed BLD in Ohio in 2012 and currently has spread to 15 states in the USA and one Canadian province. The nematode Litylenchus crenatae subsp. mccannii (Lcm) is highly associated with BLD symptoms, interveinal chlorosis and defoliation of leaves, and is currently …

Usage Of Peer Mentoring Workbooks: Enhancing The Transition Of College Students With Intellectual And Developmental Disabilities, Taylor Nicole Grout

Graduate Theses, Dissertations, and Problem Reports (ETD)

This doctoral capstone project assesses the impact and effectiveness of using peer mentoring workbooks as a tool to enhance the transition of college students with intellectual and developmental disabilities. A peer mentoring workbook was developed using theoretical frameworks to guide its design and identification of primary occupations, roles, and routines of college students. From here, four domains of college student life (dorm living, college social life, classroom management and participation, and community engagement and transportation) were developed to act as a framework for the workbook. Through the usage of Participatory Action Research, key stakeholders provided essential feedback that allowed for …

Forest Management Alters The Quantity And Apparent Stability Of Soil Carbon, Dominick Cifelli

Graduate Theses, Dissertations, and Problem Reports (ETD)

Forest carbon (C) credit markets have emerged as a tool to mitigate climate change by offsetting C emissions through improved forest management. However, the models used to estimate C gains in response to shifts in forest management focus on aboveground C pools while neglecting the role of changes in soil organic matter (SOM) pool. This absence of SOM dynamics in forest C markets is concerning given that soil holds nearly double the amount of C compared to vegetation. In addition, most research on the impacts of forest management on soil C has focused on bulk SOM concentrations. This focus overlooks …

From Class To Craft: An Investigation Into The Practice Of Acting Techniques Applied To Angelo In Shakespeare’S Measure For Measure, Charles Wesley Meeks

Graduate Theses, Dissertations, and Problem Reports (ETD)

This document examines the character development and performance process of Angelo in Measure for Measure by William Shakespeare. This production was directed by Professor Jerry McGonigle and performed in the mainstage season of 2022-2023 School of Theatre & Dance at West Virginia University. The ensuing text will outline the production process from the actor’s point of view including preparations, auditions, casting, rehearsals, performances, and final reflection. This text will include historical research, personal and directorial notes, textual analysis, table work and discussion, acting techniques, training, and education applied throughout the production period, and reflections of these experiences and discoveries.

Effectiveness Of Peer Support Groups For Mothers At Risk For Postpartum Depression, Natalie Paige Gates

Graduate Theses, Dissertations, and Problem Reports (ETD)

Motherhood requires a role transition, new maternal responsibilities, and changes in everyday life, which can impact the mother’s mental health, possibly leading to postpartum depression. Postpartum depression can, in turn, create additional challenges for the mother in engaging in her daily routines and occupations. Therefore, a peer support group for mothers at risk for postpartum depression was developed in hopes of improving the mothers’ management of routines, ultimately improving maternal mental health. The effectiveness of the peer support group was measured through quantitative and qualitative online self-report surveys, where the mothers reported their current mental health status, self-efficacy, and occupational …

Adverse Childhood Experiences Predict Mortality Risk: The Role Of Social Support & Social Strain, Meredith A. Willard

Graduate Theses, Dissertations, and Problem Reports (ETD)

Childhood adversity has long-lasting negative effects across the lifespan including increased mortality risk. The love and support individuals receive from others, also known as social support, has shown to be a protective factor against ACEs. However, little research has investigated the amplifying effects of social conflict and strain that often accompanies social relationships. Utilizing data from the Midlife Development in the U.S. (MIDUS) study, I tested whether higher levels of social support would buffer the negative effects of adverse childhood experiences on mortality risk, and whether higher levels of social strain would amplify these associations. The sample included 6,150 participants …

Tragedy Personified: Crafting The Role Of Carol In Alice Birch's Anatomy Of A Suicide, Josey Miller

Graduate Theses, Dissertations, and Problem Reports (ETD)

The purpose of the document is to chronicle the character creation of Carol in West Virginia University’s fall 2023 production of Alice Birch’s Anatomy of a Suicide. The following text will provide a detailed look at research on the playwright and my personal textual analysis in tandem with consultations with mental health professionals. It will also describe how those resources in collaboration with imaginative work via the techniques of Sanford Meisner, Fitzmaurice Voicework®, and intentional intimacy choreography were utilized in the rehearsal and performance process. In summation, it will also include post-production evaluations from loved ones and mentors as well …

A Kind Of Burr: The Fantastic Lucio In Measure For Measure, Matt Frye

Graduate Theses, Dissertations, and Problem Reports (ETD)

The purpose of this document is to detail the process of developing the role of Lucio in West Virginia University’s spring 2023 production of William Shakespeare’s Measure for Measure. This document looks at the process and methods with which I crafted my role, as well as the research I used to build a well-defined world of the play. It will explain the rehearsal process, including text analysis and design aspects which affected the creation of the role, focusing on clarity through the use of scansion and interpretations of the references in the text. To conclude, I discuss my personal experience …

Three Essays On Misinformation, Mistrust And Their Influence On Public Health Policy, Eli Kochersperger

Graduate Theses, Dissertations, and Problem Reports (ETD)

In the first chapter I identify the impact of fentanyl exposure misinformation- namely, the erroneous belief that momentary, passive contact with the potent opioid fentanyl can be seriously harmful- on first responder behavior during overdose events, and on overall opioid-related mortality. I examine changes in opioid-related mortality following one particularly well-covered episode involving an Ohio police officer in 2017, wherein the officer appeared to experience an acute opioid overdose after touching what was believed to be fentanyl. Employing a synthetic differences-in-differences identification strategy, I find areas with greater media exposure to this misinformation exhibit marked increases in opioid overdose deaths; …

Analysis Of Mutations In Protein Kinase Ck2 Linked To Okur-Chung’S Neuropathy, Shivani Maan

Graduate Theses, Dissertations, and Problem Reports (ETD)

The studies described here focus on mutations in protein kinase CK2 linked to ‘Okur-Chung’s Neuropathy’ (OCN), a neurodevelopmental disorder that involves 10 distinct mutations in the catalytic subunit CK2α. It has, however, remained unresolved if these mutations impair CK2α activity or if they also impair association with the regulatory CK2β subunit, which is necessary for assembly of the α2β2 holoenzyme. I describe efforts to resolve these questions for two mutations, Y50S and D175G. The former is thought to reside at the CK2α-CK2β interface, whereas the latter is located proximal to the active site. I therefore hypothesized that Y50S should perturb …

Dance Intervention For Stroke Rehabilitation: Restoring Occupational Performance Through Creative Movement, Olivia Paige Allen

Graduate Theses, Dissertations, and Problem Reports (ETD)

Thousands of individuals are affected by cerebral vascular accidents, (CVA), also known as strokes in the United States each year, (CDC, 2023). Cerebral vascular accidents are one of the leading causes of death among the elderly population in the U.S. each year, (NIH et al., 2023). The deficits caused by a CVA can be global, from hemiparetic limbs and sensory loss to psychosocial impacts on an individual and their support system. In occupational therapy, the goal is to regain as much function and independence as possible for the individual who has experienced a CVA. Although many evidence-based intervention tools are …

Estimating Inorganic Carbon Flux From Coal Mining Discharge Portals In The Bituminous Coal Field Region Of Pennsylvania, Lauren J. Rockwell

Graduate Theses, Dissertations, and Problem Reports (ETD)

A fundamental driver of the adverse effects associated with coal mining is the interplay of water and oxygen within mined sites, leading to the creation of coal mine drainage (CMD). One often overlooked consequence of CMD is the release of geologically-bound carbon as carbon dioxide (CO₂). The interaction of CMD with carbonate rocks, specifically the presence of sulfuric acid driving the dissolution of these rocks, leads to the release of dissolved inorganic carbon (DIC). This study examined 25 CMD locations in an approximately 2,370 km² area within the bituminous coal field region of Pennsylvania (PA), specifically in …

(Non-) Recovery Of An Agricultural Stream From Straightening And Dredging, Aras Anderson Mann

Graduate Theses, Dissertations, and Problem Reports (ETD)

In recent history, natural, meandering streams have been straightened and dredged to reduce flooding. While this practice can be effective in reducing flooding locally, it often results in the degradation of stream water quality and aquatic ecosystems. A straighter channel inherently increases the stream gradient, which could increase flow velocity, shear stress, and potentially downstream sediment yield. Studies have shown that straightened, channelized streams often begin to return to a meandering pattern 35-50 years post-channelization. Yet cross-sectional surveys and air photo analysis of the stream reach in this study, Deckers Creek, indicate little to no observable trend of the stream …