Synthetic Data–Driven Early Prediction Framework For Acute Kidney Injury In Patients Receiving Vancomycin And Ceftazidime/Avibactam, Maryam Ramazani

Graduate Theses, Dissertations, and Problem Reports (ETD)

Background: The nephrotoxic risks of combining ceftazidime/avibactam (AVI) with vancomycin (VAN) remain underexplored, despite both agents independently being linked to acute kidney injury (AKI). This study assessed the risk of AKI associated with concurrent VAN and ceftazidime/avibactam (VAN-AVI) therapy and developed synthetic data models to enable early prediction of AKI.

Methods: We conducted a retrospective analysis using electronic health record data from hospitalized adults between 2015 and 2022. The incidence of AKI was compared among patients receiving VAN-AVI or VAN in combination with piperacillin/tazobactam (VAN-TPZ) versus VAN monotherapy. AKI was defined as a composite of de novo and recurrent AKI …

Parametric Analysis Of Proppant Selection Impact On The Hydraulic Fracture And Productivity Of Extended-Reach Marcellus Shale Wells, Nicholas Hunter Lapinski

Graduate Theses, Dissertations, and Problem Reports (ETD)

Hydraulic Fracture Proppant is the gateway to reservoir connectivity, allowing for decades of natural gas production from hydraulically fractured wells in the Marcellus Shale. The proper selection of proppant can have major ramifications on the productivity of the extended-reach Marcellus shale wells. The proppant penetration into the induced fracture attempts to close the gap between the realistic non-uniform fracture conductivity and the idealistic uniform fracture conductivity. Consequently, the more proppant residing within these fractures, the more likely the proppant is to resist crushing due to the compaction. Phenomena, Advancements have been made to create more durable proppant types or proppant …

The Effects Of Operatic Voice Type On Singer Identity, Adelaide J. Mcdonald

Graduate Theses, Dissertations, and Problem Reports (ETD)

Within Western art music, voices are typically classified using the Fach system, which is based upon vocal characteristics and separates singers into the categories of soprano, mezzo soprano, contralto, counter tenor, tenor, bass, and baritone. Over time, these categories have become embedded with social and cultural meaning within the operatic world, leading to the development of stereotypes and expectations surrounding singers, as well as social categories and identities, referred to in this study as “sociocultural vocal categories” and “sociocultural vocal identity,” respectively. Currently, there are limited explorations of the sociocultural vocal categories and their associated stereotypes, with research on singer …

Recovery Of Iron And Aluminum From Acid Mine Drainage For Beneficial Uses, Katelyn Renee Pepe

Graduate Theses, Dissertations, and Problem Reports (ETD)

Acid mine drainage (AMD) is a widespread issue across the globe, in which some of the most critical cases are created by the mining industry. Researchers have investigated ways to derive benefits from AMD, such as precipitating rare earth elements (REEs) to generate potential revenue from AMD treatment and supplement market demand. However, the bulk of precipitated sludge is composed of iron and aluminum, which also have market value but are discarded in current practice.

Using the Omega site in West Virginia (WV) as a representative AMD source, the objectives of this study are (1) to determine a replicable precipitation …

Raman Spectroscopy For Rapid Quantification Of Macronutrients In Heirloom Beans, K. Chandler Williams

Graduate Theses, Dissertations, and Problem Reports (ETD)

Quantification of macronutrients in food requires a large investment in facilities and instrumentation as well as ongoing expenses of labor, reagents, and hazardous waste disposal. These costs pose a significant barrier to determining macronutrient quantities in the thousands of uncharacterized landrace and heirloom crops and discourage traditional crop breeding projects from ensuring that their selected crops maintain desirable macronutrient profiles in addition to target agronomic traits. Our objective was to test whether a hand-held Raman spectrometer—a technology which has found use in plant disease diagnostics but remains largely overlooked in nutrient quantification-- could provide a feasible means for quantifying the …

A Learning History Of A State Physical Activity Plan, Jessica Nicole Riffee

Graduate Theses, Dissertations, and Problem Reports (ETD)

Physical inactivity remains a persistent public health concern in the United States, disproportionately affecting rural populations like West Virginia. To address statewide physical activity challenges, West Virginia developed one of the nation’s first state level physical activity plans, ActiveWV: 2015, that was revised to ActiveWV: 2030. Limited research has investigated how statewide physical activity plans unfold over time or how stakeholder learning can drive improvement.

This dissertation employed a learning history action research methodology to construct a collective narrative of the development, dissemination, implementation, and evaluation activities across both iterations of the West Virginia Physical Activity Plan. Reflective interviews with …

Motivation And Well-Being: A Study Of Wvu Extension Volunteers, Amber Renae Goff

Graduate Theses, Dissertations, and Problem Reports (ETD)

Volunteers are the heart of the land-grant outreach model. They bring education and resources to communities across West Virginia. Volunteers have been relied upon in many aspects of Extension programming and current budget conditions have reduced the level of staffing within WVU Extension. There may be an increased demand for volunteers to help with programming. The purpose of this study was to investigate the relationship between motivation and the perceived level of well-being within the WVU Extension volunteer programs. The study yielded 464 responses from a descriptive survey. Based on the results, WVU Extension volunteers are motivated based on their …

Performance Is In The Eye Of The Beholder: Exploring The Moderating Role Of Psychological Perspective Distancing Within Thought Self-Leadership In An Organizational Context, Christopher Bryton Neck

Graduate Theses, Dissertations, and Problem Reports (ETD)

Self-leadership, or the process through which individuals perform various cognitive and behavioral strategies to attain the self-direction and self-motivation necessary to perform in desired ways, has consistently been evidenced to enhance individuals’ performance through promoting a variety of positive individual cognitions, such as self-efficacy, positive affect, and engagement and through diminishing key threatening mental states such as stress, negative affect, and dysfunctional thinking (Harari et al., 2021; Knotts et al., 2022). The cognitive component of self-leadership, thought self-leadership (TSL) has been found to be particularly impactful, aiding the individual to modify and adapt their dysfunctional thinking to be more constructive …

The Dark Tetrad And The Intention To Invest In Cryptocurrency, Amy Bauer-Sinicin

Graduate Theses, Dissertations, and Problem Reports (ETD)

The Dark Tetrad comprises four distinct negative personality traits with some overlapping qualities: narcissism, Machiavellianism, psychopathy, and sadism. Characterized as being risky and speculative, cryptocurrencies are not backed by government banks like fiat currencies, nor do they offer the same privacy when engaging in transactions.

Narcissists may view cryptocurrency investment as an opportunity to showcase their financial acumen, reinforcing their self-image. Machiavellians see the decentralized, loosely regulated market as ideal for exploiting opportunities through strategic manipulation. Psychopaths, drawn by the market’s volatility, may engage in exploitative schemes for personal gain. Sadists may find satisfaction in the power and control they …

The Effects Of Strip Clearcutting On Natural And Artificial Northern Red Oak Regeneration In A Central Appalachian Hardwood Stand, Patrick Aaron Plaugher

Graduate Theses, Dissertations, and Problem Reports (ETD)

There are well-known difficulties associated with regenerating oak stands throughout the Central Hardwoods region. To successfully regenerate oak, competitive sources of advance reproduction are required ahead of harvesting—a condition that is rarely present, especially on productive sites. While treatments that enhance seedling competitiveness (e.g., midstory removals, burning, vegetation control) are available, in practice, these are rarely implemented and/or effective because of large treatment costs and/or because they require delaying harvest.

As a potential alternative practice, we report the 10-yr results of a strip clearcut regeneration method. This method removes alternating 45-m wide strips across a mixed Appalachian hardwood …

Abundance Estimates And Habitat Use Of The Candy Darter In The Critical Habitat Designation Of The Gauley River National Recreation Area, David Cole Hoffman

Graduate Theses, Dissertations, and Problem Reports (ETD)

This thesis includes (1) a literature review chapter and (2) a research chapter that examines the abundance and habitat use of Candy Darters (Etheostoma osburni) in the Gauley River National Recreation Area (GARI). The Candy Darter, a small-bodied fish in the family Percidae, is an endemic and a federally endangered species in the New River drainage of West Virginia and Virginia. One of the critical habitat designations for this species is located within GARI, a reach of the river impacted by didymo (Didymosphenia geminata), where snorkeling and underwater observations were conducted to assess species abundance and …

The Professional Backgrounds And Experiences Of Higher Education Trustees And Its Influence On Decision Making, Jade J. Irving

Graduate Theses, Dissertations, and Problem Reports (ETD)

There are many complex decisions that must be made among the board of governors within institutions of higher education. Recent headlines on the decisions of trustees regarding campus closures and consolidations, program cuts, and presidential appointments have put a spotlight on the individuals responsible for making such decisions. This study examined how trustees of public 4-year institutions in the state of West Virginia perceive the value of their professional backgrounds and experiences in fulfilling their governance responsibilities. Using an explanatory sequential design, this study investigated how trustees’ professional experiences shape their decision-making processes through the theoretical lenses of sensemaking theory …

Framework For Development Environment Selection In Digital Twin Applications, Carlos Dodero Fernandez

Graduate Theses, Dissertations, and Problem Reports (ETD)

Digital Twin (DT) technology, a cornerstone of Industry 4.0, facilitates real-time synchronization between virtual models and physical manufacturing systems, enhancing operational efficiency and decision-making. However, its widespread adoption is hindered by the absence of standardized methods for selecting Development Environments (DEs) for DTs, compounded by challenges in cost, interoperability, and connectivity with Industrial Internet of Things (IIoT) protocols. This thesis proposes a Systematic Selection Framework to address this gap, offering a structured methodology to evaluate DEs based-on visualization quality, scalability, interoperability, and cost-effectiveness for manufacturing applications. The framework categorizes and compares sixteen DEs into Game Engines, Robotics Engines, and Simulation …

Investigation Of Protein-Ligand Binding Interactions Through The Computational Methods Of Molecular Dynamics And Graph Neural Networks, Alexander Benjamin Wroe

Graduate Theses, Dissertations, and Problem Reports (ETD)

Studies in protein ligand binding are a significant focus in the field of medicinal chemistry

and biochemistry, facilitating a greater understanding of the structure-function relationship

of the protein and controlling function via drug development. In this research, we identify

new binding sites for lipids on the microbial membrane protein, proteorhodopsin, and apply

machine learning approaches to accelerate the generation of binding affinity-like data for the

use in the identification of potential small molecule drugs. The platelet activating factor

receptor. Cardiolipin, a lipid in membranes, and proteorhodopsin, a microbial proton pump,

are both commonly found in microbial membranes, but little is …

Assessing The Feasibility Of The Virtual Reality Training Protocol For Sport, Jarad A. Lewellen

Graduate Theses, Dissertations, and Problem Reports (ETD)

Research has supported the use of virtual reality (VR) in sport to train skills such as decision-making and anticipation, as well as aid in injury rehabilitation. Despite this, VR is not commonly used as a training tool in sport. Barriers to its adoption include a lack of understanding, low awareness, and risk of cybersickness. As such, there is a critical need to address these barriers and promote acceptance of VR in sport. The purpose of this single-arm, non-randomized, mixed-methods feasibility trial was to examine the feasibility and acceptability of the Virtual Reality Training Protocol for Sport (VRTPS), which was designed …

Delineating Underground Geological Formations: An Integrated Lidar And Camera-Based Approach For Enhanced Feature Identification In Poorly Lit Mining Environments, Timothy James Batchler

Graduate Theses, Dissertations, and Problem Reports (ETD)

Underground mining environments present challenges in accurately identifying geological formations and potential hazards due to poor lighting conditions and confined spaces. Traditional imaging methods often fall short, making it difficult to detect critical geological features such as limestone, shale, and other rock formations. This research addresses these challenges by integrating camera imagery with Light Detection and Ranging (LiDAR) data to improve geological formation detection in poorly lit mining settings.

LiDAR, with its ability to generate high-resolution three-dimensional models in low-light or dark conditions, offers a promising solution to these limitations. By combining LiDAR’s precise 3D models with camera imagery, the …

Physics-Informed Neural Network Based Aerodynamic Modeling Framework, Nathaniel E. Michek

Graduate Theses, Dissertations, and Problem Reports (ETD)

Significant advances have been made in developing aerodynamic models over the years. While these advances span many modeling techniques and data collection methods, certain aerodynamic regimes still pose significant challenges. These regimes commonly occur when an aerodynamic body is under extreme flight conditions. Many of these conditions occur simultaneously in the rare and poorly understood case of a tumbling aerodynamic body. The flight of a tumbling aerodynamic body goes through the entire range of aerodynamic angles, alpha and beta, causing significant non-linearities and time-dependent effects associated with flow separation. During tumbling, the aerodynamic body simultaneously rotates about all three axes …

Evaluating The Adaptation Of Taro (Colocasia Esculenta) To West Virginia Climatic Conditions, Kayode Joseph Ajayi

Graduate Theses, Dissertations, and Problem Reports (ETD)

Climate change impacts agriculture and food security across the globe, therefore higher temperatures could increase in the length of the growing period and new crops would take advantages of. Research was conducted in Morgantown, WV in 2022 and 2023 to understand the growth pattern of Taro in West Virginia, and to analyzing the chemical composition of the Taro plant. The experiment was a completely randomized design in direct planting-low tunnel technology (2 replications, and 10- plants/plot), and two fertilization treatments (fertilized and non-fertilized). Spacing was 1 m within and between rows. Data were subjected to ANOVA using SAS. Dependent variables …

A Strategic Infrastructure Improvement Framework For Intermodal Transportation Networks, Ayoub Abusalih

Graduate Theses, Dissertations, and Problem Reports (ETD)

In this research, we propose a novel approach to design infrastructure networks for intermodal freight transportation systems, which incorporates railways, highways, and inland waterways (IWW). The objective of our study is to identify the optimal set of hubs to be built and operated over an extended time, based on the projected domestic cargo demand. Unlike traditional hub location models, our approach introduces hybrid hubs, where hybrid transportation modes are integrated to facilitate cargo handling. This innovative integration enables more efficient intermodal connections, leading to tangible reductions in operating costs, and carbon emissions. Specifically, we propose a mixed integer programming model …

Multifaceted Life Skills Training And Job-Orientation Supports For Individuals In Vocational Rehabilitation Programming, Laura R. Mccray

Graduate Theses, Dissertations, and Problem Reports (ETD)

There is growing support for those with an intellectual or developmental disability (IDD) in the transition process and within the workplace, however, there are areas that need to be addressed to facilitate further inclusion and success in this domain. There are structured institutions within the community that extend support for those transitioning out of high school, focusing on aligning with life training and professional skills while promoting societal integration by delivering services directly and avoiding isolation within traditional service environments (Accardo & Whitman, 2011). Growing research highlights the necessity of providing resources that support individuals with intellectual and developmental disabilities …

Predictors Of Success In Whole-Classroom Narrative Interventions For Elementary School Children, Malia Sayavong

Graduate Theses, Dissertations, and Problem Reports (ETD)

ABSTRACT

Predictors of Success in Whole-Classroom Narrative Interventions for Elementary School Children

Malia Sayavong

Purpose:

Developmental Language Disorder (DLD) is a neurodevelopmental communication disorder that significantly affects a child’s ability to acquire and use language for speaking, listening, reading, and writing. Children with DLD often experience persistent difficulties with vocabulary, grammar, comprehension, and narrative construction, which can interfere with academic achievement and social interaction. Classroom-based narrative interventions have shown promise in supporting language growth in this population, yet not all students benefit equally. Multiple individual characteristics—including language profiles, cognitive abilities, and environmental factors—may influence intervention outcomes. Therefore, the purpose of …

The Effect Of Facial Phenotypes On Differential Performance Of Facial Recognition, Evan R. Garrett

Graduate Theses, Dissertations, and Problem Reports (ETD)

Facial recognition technology is utilized in many facets of life. As the use has become more widespread these systems have improved in reliability and performance approaching the level of human accuracy. With these improvements the problem of bias still remains as a persistent problem. Efforts have been made to minimize the bias prevalent in the systems via studies into various demographic factors, creating training datasets that have a more uniform distribution of subjects, and other methods. As facial recognition is one of the most utilized forms of biometric recognition it is vital to analyze potential causes of bias to help …

Chopin’S Innovation And Influence On The French Piano School: From His Predecessors To His Principal Students And Successors, Wenjun Xia

Graduate Theses, Dissertations, and Problem Reports (ETD)

Chopin’s Innovation and Influence on the French Piano School: From his Predecessors to his Principal Students and Successors

Wenjun Xia

This research explores Frédéric Chopin's (1810–1849) innovations in piano technique, pedagogy, composition, and interpretation, as well as Chopin’s subsequent influence on the French piano school. Before Chopin’s arrival in Paris, the French piano school was primarily influenced by Louis Adam (1758–1848) and Friedrich Kalkbrenner (1785–1849), whose approaches dominated piano pedagogy at the Paris Conservatoire. Early French piano pedagogy centered on finger precision, virtuosity, and clarity, but expressivity was somewhat limited. Chopin initiated Romantic trends that emphasized emotion and natural physical …

The Barbosa Model: Supporting Faculty In Online Course Development Through A Structured Instructional Design Approach, Gabriela Martin Barbosa

Graduate Theses, Dissertations, and Problem Reports (ETD)

The expansion of online education has amplified the need for structured, pedagogically informed faculty development. This study explored the implementation of the Barbosa Model—an instructional design framework developed to support faculty in creating effective, engaging, and well-aligned online courses. Grounded in established instructional theories and tailored to institutional needs, the model guides faculty through five phases: Existing Course, Mapping Structure, Review, Design, and Evaluation.

The study conducted at West Liberty University used pre- and post-interviews, faculty reflections, and thematic analysis to evaluate the model’s influence on faculty perceptions, instructional strategies, and professional growth. Findings revealed that while faculty perceptions of …

Academic Agency Within The Curricular Reform Of Gateway Stem Courses: A Faculty Perspective, Katie Beck

Graduate Theses, Dissertations, and Problem Reports (ETD)

The research regarding faculty agency during curricular reform is a burgeoning field within higher education as the faculty perspective within the current research concerning curriculum reform is limited. This study seeks to illuminate the faculty perspective of the curricular reform process of gateway STEM courses and how faculty experienced the reform process through a qualitative case study. The site of the case study is a public four-year institution on the eastern coast of the United States that has undergone and continues to undergo significant academic restructuring. The research utilized a structured survey and semi-structured interviews with seven total participants from …

A Quality Improvement Project To Assess The Impact Of A Patient Acuity Tool On Nurse Satisfaction In Equitable Patient Assignments In Nurse Workload And Perceived Quality Care Provided, Claire Alexandra Rodgers

Graduate Theses, Dissertations, and Problem Reports (ETD)

Background: Traditional nursing staffing models used to create patient-care assignments do not account for patient acuity. As patient acuity increases, nurse workload increases. When patient-care assignments do not account for acuity, nurses are unable to provide quality care to patients. Utilizing a patient acuity tool (PAT) has been shown to improve nurse satisfaction and equity in assignments while also enhancing the ability for nurses to provide quality care.

Purpose: The project aims to assess the impact of a PAT to improve nurse satisfaction in equitable patient assignments based on nurse workload and perception of quality of care provided to patients …

Identifying Factors Associated With Time To Diagnosis For Symptomatic Intestinal Malrotation In Pediatric Patients, Katie E. Corcoran

Graduate Theses, Dissertations, and Problem Reports (ETD)

Intestinal malrotation is a rare condition in which the intestines rotate improperly during embryonic development. Intestinal malrotation is typically diagnosed in pediatric patients with an upper gastrointestinal imaging (UGI) series. Longer time to diagnosis of intestinal malrotation increases the risk of mortality and severe morbidity. While the need for timely diagnosis is well-established in the literature, the correlates of time to diagnosis are largely unknown. The classic medical presentation for intestinal malrotation is an infant presenting with green bilious emesis. I hypothesize that time to diagnosis of intestinal malrotation will be longer in symptomatic pediatric patients when they present differently …

Improving Neuromuscular Blockade Surveillance In Anesthesia Care With Quantitative Train Of Four Monitoring, Carley S. Blair

Graduate Theses, Dissertations, and Problem Reports (ETD)

Problem Statement: Despite the availability of quantitative train of four (TOF) monitoring, anesthesia providers more frequently rely on tactile (qualitative) TOF monitoring, which is associated with underestimation of recovery from muscle relaxation. Inadequate recovery from muscle relaxants results in residual weakness and its associated complications in the postoperative period, including compromised respiratory function (Thilen et al., 2023).

Background: Neuromuscular blockade (NMB) drugs are required to facilitate endotracheal intubation and allow for surgical manipulation. When these drugs are used, train of four (TOF) stimulations are used to monitor and assess the depth and recovery from NMB. TwitchView monitors (quantitative monitoring) is …

Code Blue Narrator Documentation: An Evidence Based Quality Improvement Initiative, Stefanie A. Benvenuto

Graduate Theses, Dissertations, and Problem Reports (ETD)

Background: The code documenter plays a crucial role in ensuring accurate, real-time documentation during Code Blue events, which is critical for patient care and compliance with established guidelines and protocols. However, nurses have reported discomfort with the Code Narrator tool in EPIC, which has hindered effective documentation during these high-pressure situations.

Purpose: The lack of comfort in using the Code Narrator tool has led to inconsistent and inaccurate documentation during Code Blue events, potentially impacting the effectiveness of the response and patient outcomes, such as the achievement of return of spontaneous circulation (ROSC).

Intervention: An educational competency …

Role Of Interpretation Bias Related To Pain In A Dental Setting, Jeongwi An

Graduate Theses, Dissertations, and Problem Reports (ETD)

Studies of interpretation bias related to pain have consistently shown that patients with pain are more likely to interpret ambiguous stimuli as related to pain than healthy control participants. This phenomenon is associated with pain and related outcomes, including depression, anxiety, and avoidance behaviors, suggesting a potential target in pain management. This study aimed to examine whether the association between interpretation bias, pain, and emotional status can be replicated in a dental care population. The relation of interpretation bias to pain experience was tested in a naturalistic anxiety and pain-provoking setting (i.e., root canal treatment, RCT). A total of 82 …