Digital Commons Network^™

Improving Access To Treatment For Alcohol Use Disorder For Veterans: An Evidence-Based Practice Policy Analysis, Mary Rizzo

Graduate Theses, Dissertations, and Problem Reports (ETD)

Introduction: Alcohol use disorder (AUD) is common among veterans and is associated with poor health outcomes. Although extended-release naltrexone (XR-NTX) is an effective treatment, maintenance injections at the VA Pittsburgh Healthcare System are only available at the main medical center, requiring many veterans to travel long distances each month.

Purpose: The purpose of this evidence-based practice policy analysis was to evaluate the feasibility of offering XR-NTX injections at Community-Based Outpatient Clinics (CBOC) and develop a policy recommendation to improve access to care.

Intervention: This project examined the current XR-NTX administration process and compared it with alternative approaches used within the …

The Histamine-3 Receptor In Cardiac Fibrosis: A Novel Role In Fibroblast Function, Heather Linsky

Graduate Theses, Dissertations, and Problem Reports (ETD)

In the United States, heart failure affects approximately 6.7 million individuals. Despite a number of available therapies, heart failure prevalence continues to grow, suggesting the need for a broader range of effective therapies. More specifically, heart failure with preserved ejection fraction comprises approximately 50% of all heart failure cases and, as the name suggests, is a disease of diastolic dysfunction as opposed to systolic dysfunction. A hallmark of heart failure with preserved ejection fraction is myocardial fibrosis, which is a key contributor to diastolic dysfunction, and is the major focus of this dissertation work. In the heart, histamine-3 receptor activation …

Factors Influencing Eastern Wild Turkey (Meleagris Gallopavo Silvestris) Productivity And Nesting Chronology In West Virginia, Kirstin Palumbo

Graduate Theses, Dissertations, and Problem Reports (ETD)

Identifying drivers of variation in the timing of breeding behaviors, such as courtship activities and nesting chronology, is important for the effective management of avian species. Likewise, productivity is an important component of game bird population dynamics and can be broken up into multiple components such as the probability of nesting, clutch size, and nest success. One species that experiences a relatively long reproductive season is the Eastern wild turkey (Meleagris gallopavo silvestris). Contemporary research in the southeastern United States has raised concerns regarding declines in both wild turkey populations and overall productivity. West Virginia, however, is unique …

Multimodal Representation Learning For Face Understanding: From Caption Supervision To Foundation Model Adaptation, Md Mahedi Hasan

Graduate Theses, Dissertations, and Problem Reports (ETD)

The rapid advancement of intelligent surveillance systems and the increasing demand for reliable biometric identification in border security, public safety, and digital forensics require robust face understanding under unconstrained conditions, including low resolution, pose variation, and occlusion. While Vision Transformer (ViT)-based foundation models have greatly improved visual representation learning, their patch-based tokenization and lack of spatial inductive bias limit their ability to capture fine-grained details in low-resolution inputs. This dissertation investigates multimodal representation learning for face understanding through natural language supervision, large-scale face-caption pre-training, and parameter-efficient foundation model adaptation. It hypothesizes that textual supervision provides complementary semantic cues that improve …

Multi-Timescale Monitoring And Modeling For Resilient Smart Grids: Pmu Anomaly Detection And Battery Digital Twins, Muhammad Imran Hossain

Graduate Theses, Dissertations, and Problem Reports (ETD)

Modern power systems face failures at very different timescales. Cyber-physical disturbances may emerge within seconds, while battery degradation develops over hundreds of operating cycles. Both monitoring problems share the same underlying difficulty: power systems produce measurement data in abundance, but reliably labeled examples of abnormal or degraded operation are scarce. Rare grid events are difficult to label, and battery degradation data are heterogeneous across cells, cycling protocols, and chemistries. This thesis addresses these challenges through two complementary domain-informed learning frameworks that constrain representation learning using information specific to each physical problem.

First, at the system level, T-BiGAN, a Transformer-augmented bidirectional …

A Mixed Methods Study Of The Transition To Adult Health Care For Sexual Minority Young Adults With Chronic Pain: Understanding The Impact Of Stigma, Cecily Newel Conour

Graduate Theses, Dissertations, and Problem Reports (ETD)

Sexual minorities with chronic pain are likely to experience stigma stemming from their sexual identity and chronic pain. Pain stigma and sexual minority stigma are associated with increased health disparities and differences in health care utilization, particularly for adults. The transition to the adult health care system appears to be a critical point to understand the impact of stigma on health care utilization to then improve outcomes. With a sample of 48 sexual minority young adults with chronic pain, the current study investigated transition experiences using an explanatory, sequential mixed-methods design that was both observational and cross-sectional. Participants completed quantitative …

A New Parsimony-Based Method For Reconstructing Sequences Of Developmental Events And Estimating Rates Of Intraspecific Variation, With Applications To Trilobites, Alexander Benjamin Bradley

Graduate Theses, Dissertations, and Problem Reports (ETD)

Ontogenetic Sequence Analysis (OSA) is a method for reconstructing multiple sequences of abrupt phenotypic transformations (developmental events) for sampled populations of any kind of organism. It makes use of cladistic parsimony software to produce a network, or graph, whose vertices represent unique phenotypes at different stages of maturity (“semaphoronts”) and whose edges describe the developmental events occurring between semaphoronts. It is a powerful tool for constraining the range of developmental variation possible for a given species and generating sample statistics capable of identifying both the most common and the outlier ontogenetic sequences. However, OSA has seen little use since its …

Development Of Novel Methods For Investigative Leads In Firearm And Explosive Related Incidents, Addio Joseph Fiordigigli Jr.

Graduate Theses, Dissertations, and Problem Reports (ETD)

Criminal outbreaks and gun violence persist as a multifaceted global crisis, marked by escalating rates of homicide, suicide, and terrorism that destabilize communities and strain public resources. The proliferation of illicit firearms and homemade explosive devices, along with the complexity of modern criminal networks, necessitates innovative scientific tools to strengthen preventive intelligence operations and ensure that the legal process is grounded in physical evidence. More efficient detection of traces left behind at a crime scene can help prevent further harm or injury from follow-up attacks. This study aims to develop and evaluate new triage methods for characterizing gunshot residues (GSR) …

Optimization Of The Cmc Algorithm, Christopher Joseph Moner

Graduate Theses, Dissertations, and Problem Reports (ETD)

Cartridge cases recovered from discharged firearms contain tool marks produced by the internal mechanisms of said firearm. Firearm and tool mark examiners com pare these marks to determine whether two cartridge cases originated from the same firearm. Traditional comparison methods have been criticized for their subjective nature and reliance on examiner interpretation rather than objective decision thresholds. The Congruent Matching Cells (CMC) algorithm was developed as a quantitative, objective method for tool mark comparison. CMC is a surface topography correlation algorithm that partitions a tool mark into small regions, or cells, and evaluates their similarity using the areal cross-correlation function …

Student Support In Civil And Environmental Engineering, Heather Marie Rice

Graduate Theses, Dissertations, and Problem Reports (ETD)

Many student support services target first-year engineering students to help improve their transition from high school to college and to reach first-year retention goals. These opportunities are communicated to students through a variety of ways. The objectives of this work are to evaluate student perspectives of student services support factors in a civil and environmental engineering program and investigate how student support services and opportunities are communicated to students in a civil and environmental engineering program. The media identified for student support service outreach were the fundamentals of engineering program newsletters, academic advising newsletters, Statler eNews newsletters, and the bulletin …

Global Weak Solutions Of Optical Variational Wave System, Shahrazad Hamed Alnafie

Graduate Theses, Dissertations, and Problem Reports (ETD)

The coupling of a variational wave equation with Maxwell’s equations gives rise to the optical variational wave system, a hyperbolic PDE system that models the director field of the nematic liquid crystals. This system presents unique analytical challenges that have not been addressed in the existing literature. In this dissertation, we study the one-dimensional case of this system.

We establish the global existence of conservative weak solutions to the associated Cauchy problem. The hyperbolic system is derived using the energy variational method. Through a sequence of suitable coordinate transformations, we reformulate the system while preserving its hyperbolicity. Due to degeneracy …

Survival, Cause-Specific Mortality, Resource Selection, Movement Rates, And Population Dynamics Of White-Tailed Deer (Odocoileus Virginianus) In West Virginia, Usa, Brett P. Skelly

Graduate Theses, Dissertations, and Problem Reports (ETD)

White-tailed deer (Odocoileus virginianus) are one of the most culturally and economically important big game species in the United States. At the turn of the 20th century white-tailed deer were almost extirpated due to market hunting and unsustainable forestry practices that destroyed habitat. The creation of game laws that eliminated market hunting and created seasons and bag limits for deer hunting along with restocking efforts by sportsmen’s groups and state wildlife agencies aided in deer population recovery. These efforts have led to the abundant deer populations that are currently enjoyed by hunters and wildlife viewers. Deer populations require …

The Hidden Costs Of Consumption: A Multi-Context Investigation On Stigma And Social Judgment, Siti Nuraisyah Suwanda

Graduate Theses, Dissertations, and Problem Reports (ETD)

Consumption is not always as simple as an exchange of value between a buyer and a seller. In many contexts, what individuals choose to consume or not consume can carry social meaning, leading to judgment and devaluation. While prior research has explored stigma broadly in marketing and consumer behavior, less attention has been given to stigma that caused specifically by consumption choices. This dissertation addresses this gap by examining how consumption becomes socially evaluated and judged across different contexts, with the goal of advancing both theoretical understanding and practical insights into socially sensitive consumption.

Essay One develops the foundation by …

Disaster Exposure, The Perception Of Physiological Pain, And Psychological Distress Across Adulthood, Esha Azhar

Graduate Theses, Dissertations, and Problem Reports (ETD)

Climate change brings with it an increase in the occurrence of natural disasters, such as hurricanes, wildfires, severe storms, etc. In the aftermath, afflicted individuals may suffer adversely, especially in their physical and mental health. Previous research has found older adults to be faring better after experiencing a disaster compared to younger adults, which has been attributed to their better mental health associated with aging and gaining experience with adversities (Strough et al., 2023; 2025). The current study examined the psychological distress and physiological pain of individuals across the adult lifespan after experiencing a disaster. Participants were part of the …

Resilience And Reactivity: The Relation Between John Henryism And Cardiovascular Responses To Laboratory Stressors In An Appalachian Sample, Emma Raycher Thompson

Graduate Theses, Dissertations, and Problem Reports (ETD)

John Henryism active coping (JHAC), named for folk hero John Henry, is defined as the perception that one can overcome stressors through hard work (James et al., 1983). This construct has been tied to numerous health outcomes, showing a negative influence on cardiovascular health (Bennett et al., 2004). Many researchers have examined the relation between JHAC and cardiovascular reactivity to stress, though findings are mixed. Further, despite the legend of John Henry occurring in Appalachia, and traits associated with John Henryism, such as resilience, being prominent within this region, no study has examined the relation between JHAC and reactivity in …

I Think, Therefore I Can: Self-Efficacy, Self-Regulation, And Sense Of Belonging In Introductory Physics, Danielle Christine Maldonado

Graduate Theses, Dissertations, and Problem Reports (ETD)

Cognitive and affective beliefs in physics classrooms are important indicators of student success beyond traditional measurements of academic performance. This body of work explores major beliefs and processes, including self-efficacy, self-regulation, and sense of belonging, as they relate to academic achievement among introductory undergraduate physics students. First, this dissertation explores the development of physics self-efficacy and physics sense of belonging, two highly correlated variables. This work identifies unique sources of physics self-efficacy and sense of belonging development from current and prior academic experiences, personality factors, and demographic variables. Then, relationships between early- semester self-efficacy and sense of belonging, mid-semester …

Electronic Cigarettes Increase Blood-Brain And Blood-Tumor Barrier Drug Efflux In A Preclinical Lung Cancer Model Of Brain Metastasis, Cullen Parker Wolford

Graduate Theses, Dissertations, and Problem Reports (ETD)

This dissertation (a) provided a comprehensive review of the known therapeutic challenges in nicotine delivery system users with lung cancer and (b) investigated the impact of electronic cigarettes on blood-brain/blood-tumor barrier function and efficacy of small molecule KRAS inhibitors in a syngeneic lung cancer brain metastasis model. The blood-brain barrier is a physiochemical barrier that limits systemic delivery of therapeutics into brain. When tumors invade the central nervous system, the blood-brain barrier is disrupted and subsequently forms a blood-tumor barrier. Despite the inherent leakiness and variable permeability of the blood-tumor barrier, it continues to restrict anti-cancer drugs from accumulating at …

Ai-Based Smart Proxy Models For Flow Assurance, Integrating Oil Rate Prediction, Pipeline Monitoring, And Leak Detection, Ali Sajedian

Graduate Theses, Dissertations, and Problem Reports (ETD)

Oil and gas pipeline networks operate under complex multiphase flow conditions and dynamic transient regimes that present significant challenges for traditional monitoring, anomaly detection, and operational decision-making methodologies. Many existing monitoring approaches rely on high-fidelity physics-based transient flow simulations to accurately represent system behavior. However, these models are computationally intensive and therefore difficult to implement in real-time operational environments.

This dissertation presents a physics-guided artificial intelligence framework for intelligent pipeline monitoring and integrity management based on the concept of Smart Proxy Modeling. By integrating first principles engineering knowledge with machine learning techniques, the proposed framework develops computationally efficient surrogate models …

Revival Through Resilience In The Post-Mined Landscape: Demonstrating The Socio-Economic Context Of Appalachia And Exploring How Community Infrastructure And Cultural Tourism Can Be Catalysts For Economic Regeneration In Appalachian Communities, Azita Tasnim Ritu

Graduate Theses, Dissertations, and Problem Reports (ETD)

Post-industrial communities across Appalachia continue to experience economic and environmental challenges following the decline of coal mining and related industries. Towns such as Smithers and Montgomery, West Virginia, reflect these conditions through economic stagnation, population loss, aging infrastructure, and degraded landscapes, creating an urgent need for sustainable redevelopment strategies.

The Appalachian Regional Commission emphasizes economic diversification, infrastructure investment, and community revitalization as critical components for improving regional quality of life. However, many former mining communities continue to struggle with underutilized heritage assets, degraded landscapes, and limited economic alternatives. Cultural landscapes and local identity remain significant but often overlooked resources that …

Studying The Mechanism For Ricin-Induced Growth Suppression, Daniel Judge

Graduate Theses, Dissertations, and Problem Reports (ETD)

This study focuses on ribosome-inactivating proteins (RIPs), a class of potent toxins that includes ricin, α-sarcin, and shiga toxin, which irreversibly damage large subunit rRNA. Although the catalytic activity of ricin toxin A chain (RTA) is well characterized, the precise mechanisms linking ribosome damage to altered cellular morphology remain poorly understood. In this study, we engineered a tetracycline-regulatable expression system to express RTA in Saccharomyces cerevisiae. We characterized the effects of RTA expression on yeast growth, viability, and reproductive potential. We demonstrated that our expression system produced rapid and robust RTA expression and ribosome depurination within less than one …

Evaluation Of Potential Factors Limiting The Expansion Of Invasive Carp (Hypophthalmichthys Spp.) In The Ohio River Basin, Erin Shepta

Graduate Theses, Dissertations, and Problem Reports (ETD)

The introduction of aquatic invasive species is one of the greatest threats to freshwater biodiversity around the world. Two species of invasive carp, bighead carp (Hypophthalmichthys nobilis) and silver carp (H. molitrix) have spread throughout much of the Mississippi River Basin, resulting in serious ecological impacts to native communities. Their spread in the Ohio River, a major tributary of the Mississippi River, appears to have slowed, with limited evidence of upstream advancements. Here, we investigated abiotic and biotic factors that may be contributing to the reduced spread of invasive carp in the Ohio River Basin. Generally, …

Constructing The 'Other': A Cda Of Social Actor Representation And Agency Attribution In The New York Times Reporting On Palestine And Israel (2023–2025), Faithlyn H. Graham

Graduate Theses, Dissertations, and Problem Reports (ETD)

Media organizations play a central role in shaping public understanding of international conflict. Following the publication of a leaked internal editorial memorandum from The New York Times in 2024 advising reporters to avoid terms such as "genocide," "ethnic cleansing," and "occupied territory," questions emerged regarding institutional influence and ideological framing in coverage of the Palestinian and Israeli conflict. This study examined how The New York Times discursively constructed the conflict between October 7, 2023, and October 10, 2025, using Critical Discourse Analysis (CDA) informed by KhosraviNik's (2010) three-level analytical framework. A purposive sample of 119 hard-news articles was analyzed using …

Evaluation Of Acid Mine Drainage Treatment In The Upper Deckers Creek Watershed, Sarah E. Nelson

Graduate Theses, Dissertations, and Problem Reports (ETD)

Acid mine drainage (AMD) is a legacy contaminant, impairing Appalachian watersheds despite decades of regulatory work and investment in remediation. This study analyzes and evaluates the performance of seven AMD treatment systems (5 passive and 2 active) as well as thirteen untreated sources in the headwaters of Deckers Creek. Monthly influent and effluent samples measuring pH, major metals, and acidity were collected from January 2024 through 2026 to assess variability in treatment performance, and engineering site visits were conducted for each treatment system. Based on these two components, recommendations customized for each individual treatment system were made, and the implementation …

Effect Of Yoga On Non-Invasive Measures Of Cardiovascular Functioning And Health, Alexis Nicole Thrower

Graduate Theses, Dissertations, and Problem Reports (ETD)

Introduction: Cardiovascular disease (CVD) has been the number one cause of death worldwide and within the United States (US) for decades. Effective and practical prevention modalities are needed to reduce the burden of this often-preventable condition. Physical activity is an effective and modifiable behavior for CVD risk management; however, only one in four adults meet current physical activity guidelines. Some types of yoga, including vinyasa yoga, are a form of physical activity, and vinyasa yoga efficiently incorporates moderate-intensity aerobic activity, muscular-strengthening movements, and flexibility components. Yet, minimal rigorous research evaluates yoga’s effects on health. The purpose of this dissertation is …

Plant-Wide Process Modeling, Techno-Economic Optimization, And Bayesian Uncertainty Quantification For Manufacturing Value-Added Products From Lignocellulosic Biomass, Poulomi Das

Graduate Theses, Dissertations, and Problem Reports (ETD)

For decades, many chemicals have been produced from fossil resources, contributing to resource depletion, pollution from extraction and refining, and hazardous byproducts. Growing environmental concerns and declining fossil reserves have intensified the search for sustainable sources of fuels, energy, and chemicals. Lignocellulosic biomass, the only abundant renewable carbon source, is therefore being explored as a feedstock for second-generation biofuels and high-value chemicals.

Currently, global wood-panel industry heavily depends on petroleum-derived commercial adhesives like phenol-formaldehyde, urea-formaldehyde, etc. These formaldehyde-based chemicals cause hazards to both human health and environment through emission of toxic volatile organic compounds. Typically, lignin is considered as one …

Hyperglycemia Detection From Single-Lead Ecg Using A Hybrid Cnn & Transformer Model, Adam Ayomikun Ogunjembola

Graduate Theses, Dissertations, and Problem Reports (ETD)

Diabetes Mellitus is known as high blood glucose. This high blood glucose level happens when the body has a problem with producing or using insulin. Insulin is a very important hormone that the pancreas makes to control how much glucose gets into the bloodstream and cells. Diabetes Mellitus has an effect on the body if it is not treated, such as damaging the blood vessels and nerves which can lead to stroke, kidney failure, heart attack and permanent loss of vision. Since people with diabetes need to measure their glucose levels in order to determine how much insulin or medicine …

Social Media Appearance Pressures And Body Dissatisfaction In Collegiate Athletes: Model Refinement, Group Differences, And Exploratory Insights, Hannah Hunter Miller

Graduate Theses, Dissertations, and Problem Reports (ETD)

In considering athletes’ body image, it is necessary to examine the psychosocial factors, and related psychological processes, that influence it. The body-related pressures athletes experience while navigating social media represent a relatively new and increasingly influential factor that warrants further investigation. The purpose of this study was threefold: (1) to replicate and refine Miller and colleagues’ (in press) model; (2) to examine differences in model variables and relationships across demographic and contextual groups; and (3) to explore aspects of social media perceived as contributing to appearance pressures, as well as strategies athletes may use to mitigate these pressures and their …

Feasibility Of Parent-Child Interaction Therapy-Toddler In Community Clinics In The United States And Japan, Sharon T. Phillips

Graduate Theses, Dissertations, and Problem Reports (ETD)

The toddler age (12-36 months) is characterized by a toddler’s increasing desire for autonomy, which can result in caregiver-child conflict and toddler externalizing problems (Kohlhoff & Morgan, 2014). Clinical levels of disruptive behavior in toddlerhood can be predictive of a host of negative outcomes, including problems with academic achievement and delinquency (Copeland et al., 2007; Milledge et al., 2019). High levels of toddler behavior problems also are associated with poor caregiver-child relationships and poor toddler emotion regulation skills (Beijers et al., 2013; Umemura et al., 2022). Thus, interventions targeting toddler behavior problems need to focus on strengthening the caregiver-child relationship …

Enhancing Occupational Engagement And Wellness In Middle-Aged And Retired Adults Through Movement And Mindfulness Program Development, Erin J. Harvey

Graduate Theses, Dissertations, and Problem Reports (ETD)

Occupational imbalance and a diminished sense of purpose are common challenges faced during middle age and the transition into retirement. These issues can contribute to increased burnout, decreased participation in meaningful activities, and an overall decline in health and well-being. Occupational therapy is well-equipped to address these concerns through comprehensive and holistic, occupation-based wellness programs that promote healthy routines and engagement in meaningful roles. This doctoral capstone project involved developing and implementing two community-based wellness programs tailored to different populations. The first program included self-paced wellness modules for middle-aged adults, aiming to encourage healthy lifestyle habits, enhance coping skills, and …

Computer Vision Methods For Rfi Segmentation In Radio Astronomy, Yechan Kweon

Graduate Theses, Dissertations, and Problem Reports (ETD)

Radio Frequency Interference (RFI) increasingly contaminates the radio astronomy spectrum, often exceeding astronomical signal amplitudes by 50–70 dB. Reliable detection and mitigation are therefore essential for studies of faint transient phenomena such as pulsars and fast radio bursts (FRBs). Existing practical methods including Spectral Kurtosis (SK), Median Absolute Deviation (MAD), and SumThreshold perform well in many settings but depend on assumptions about the RFI environment and data statistics, limiting their effectiveness for weak, broadband, or nonstationary interference.

We develop a transform based RFI detection method that requires no prior knowledge of the RFI origin or type. The method operates on …