Digital Commons Network^™

The Effect Of Sars-Cov-2 On Bacterial Diversity And Abundance In Community Wastewater, Joshua Lambert

Graduate Theses, Dissertations, and Problem Reports (ETD)

Severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) enters human respiratory cells through binding of its spike (S) protein to the ACE-2 receptor, which is highly expressed in lung cells, but is also found in over 150 other cell types encompassing major organs including GI enterocytes. SARS-CoV-2 causes gut dysbiosis in infected individuals and patients with COVID-19 and also coincides with lower alpha diversity of the individual’s gut microbiome. Certain gut microbiome-associated genera are lower in abundance in COVID-19 patients including Lachnospira, Prevetolla, Roseburia, Bifidobacterium, and Faecalibacterium while genera such as Bacteroides, Enterococcus and Proteobacteria are increased during a SARS-CoV-2 …

Synthetic Data–Driven Early Prediction Framework For Acute Kidney Injury In Patients Receiving Vancomycin And Ceftazidime/Avibactam, Maryam Ramazani

Graduate Theses, Dissertations, and Problem Reports (ETD)

Background: The nephrotoxic risks of combining ceftazidime/avibactam (AVI) with vancomycin (VAN) remain underexplored, despite both agents independently being linked to acute kidney injury (AKI). This study assessed the risk of AKI associated with concurrent VAN and ceftazidime/avibactam (VAN-AVI) therapy and developed synthetic data models to enable early prediction of AKI.

Methods: We conducted a retrospective analysis using electronic health record data from hospitalized adults between 2015 and 2022. The incidence of AKI was compared among patients receiving VAN-AVI or VAN in combination with piperacillin/tazobactam (VAN-TPZ) versus VAN monotherapy. AKI was defined as a composite of de novo and recurrent AKI …

Dynamic Force Feedback Controller Improves Metrics Of Stepping In A Biomimetic Robot Leg, Isabella Mae Kudyba

Graduate Theses, Dissertations, and Problem Reports (ETD)

Force feedback is a type of robotic control where forces are measured, fed back into the control system, and actuation is adjusted to compensate for environmental forces, with the goal of quick and precise limb positioning in walking. Robots of today use single force sensors (e.g. pressure sensitive pads, load cells) per leg which are often bulky, expensive, and susceptible to crosstalk. Walking robots often employ model predictive controllers or policy controllers trained through reinforcement learning (RL) to actuate their limbs, but these methods are time and energy consuming. Biomimetic robots offer an alternative approach, investigating biological theories with the …

Modeling And Simulation Of A Process For Upcycling Of Low-Density Polyethylene Plastic Waste To Ethylene, Xiaoyan Wang

Graduate Theses, Dissertations, and Problem Reports (ETD)

Ethylene is one of the most widely produced petrochemicals, with an estimated global output of 180 million metric tons in 2022. Approximately 82 million metric tons of ethylene are used annually for plastic production, primarily for polyethylene (PE), as well as polypropylene (PP) and polyvinyl chloride (PVC). The CO₂ emissions associated with PE production were approximately 14 million metric tons in 2022. Globally, an estimated 70 million metric tons of PE are produced and consumed each year, with the majority (~79%) ending up in landfills or the environment.

This project proposes a novel process in which waste low-density polyethylene (LDPE) …

The Position Of The United States Of America Vis-A-Vis The Question Of Western Sahara: Assessing The Role Of Think Tanks In The Conflict, Hamid Baadeche

Graduate Theses, Dissertations, and Problem Reports (ETD)

ABSTRACT

The Position of the United States of America Vis-à-vis the Question of Western Sahara: Assessing the Role of Think Tanks in the Conflict

Hamid Baadeche

Think tank organizations, particularly in the United States, have become a prominent feature of the political landscape. They act as advocates for specific policies that they consider beneficial for the country or a particular societal group. They function as a primary source of information, which they then aim to transform into well-informed policies and sound decisions. They are referred to as "the revolving doors," "idea brokers," and "idea factory." As such, their foremost objective …

Characterization Of Properties And Defects Of Alternative Matrix Materials For 3d Printed Continuous Carbon Fiber Reinforced Composites, Noah Darren Osborne

Graduate Theses, Dissertations, and Problem Reports (ETD)

Additive manufacturing, commonly known as 3D printing, has the potential to transform the production of end-use parts by facilitating the creation of complex shaped, low-volume components that are expensive to manufacture using traditional methods. However, thermoplastic polymer matrices currently utilized in 3D printing of carbon fiber composites, often lack the mechanical properties needed for aerospace applications. To address this issue, researchers have developed fiber-reinforced 3D-printed composites using an innovative two-step process which involves printing 3D preforms using fused deposition modeling, followed by compression molding. However, most previous work involves the use of nylon-based polymer matrices while there are a number …

Evaluation Of Small Unmanned Tailsitter Hybrid Air Vehicles Via Full Flight Simulation, Andrew Spencer Winters

Graduate Theses, Dissertations, and Problem Reports (ETD)

Small Unmanned Aerial Vehicles have exploded in popularity in the past 15 years among researchers and for industrial uses such as agriculture, search and rescue, and infrastructure inspection. Fixed wing and multirotor designs present two major paths that can be taken with these technologies. Fixed wing platforms have superior aerodynamic efficiency but require large areas for takeoff/landing and cannot hold a constant position in space, limiting their use. Multirotor configurations offer a more versatile platform that can maneuver in 3 dimensions independently but lack the endurance of fixed wing vehicles. This thesis analyses a quadrotor biplane and a variable wingspan …

Recovery Of Iron And Aluminum From Acid Mine Drainage For Beneficial Uses, Katelyn Renee Pepe

Graduate Theses, Dissertations, and Problem Reports (ETD)

Acid mine drainage (AMD) is a widespread issue across the globe, in which some of the most critical cases are created by the mining industry. Researchers have investigated ways to derive benefits from AMD, such as precipitating rare earth elements (REEs) to generate potential revenue from AMD treatment and supplement market demand. However, the bulk of precipitated sludge is composed of iron and aluminum, which also have market value but are discarded in current practice.

Using the Omega site in West Virginia (WV) as a representative AMD source, the objectives of this study are (1) to determine a replicable precipitation …

Novel Design And Fabrication Of A High-Speed Transient Heat Flux Sensor For Application To Rotating Detonation Engines, Zachary Todd Tallman

Graduate Theses, Dissertations, and Problem Reports (ETD)

Rotating detonation engine (RDE) combustion systems have been a topic of interest in the pressure gain combustion community for their benefits over traditional gas turbine engine combustors. However, cooling requirements for these engines are significantly higher and less predictable than those of non-detonating engines. To understand and quantify the high-speed heat transfer dynamics within an RDE, a novel high-frequency heat flux sensor is presented. This study aims to design a robust, single-sided sensor that can withstand the high temperature and harsh environment of an RDE for extended durations. Screen printing is used to deposit a layered, platinum-yttria-stabilized zirconia (YSZ) film …

Imitation Learning In Robotic Manipulation Using Diffusion Models, Marlon Domingues De Oliveira

Graduate Theses, Dissertations, and Problem Reports (ETD)

This work deals with the problem of teaching robots by demonstration, also known by imitation learning. The main objective of this area of research is to enable the autonomous execution of complex robotic tasks using neural networks trained on expert-generated data, thus allowing the transfer of human knowledge to machines. To this end, this thesis describes an experimental setup especially designed for the study of imitation learning in robotic manipulation tasks and the adaptation and evaluation of a previously published technique to this setup. The experimental setup developed in this work is based on the Franka Emika Research 3 manipulator, …

Characterizing Nursery Habitat For Juvenile Invasive Carp (Hypophthalmichthys Spp.) On The Ohio River, Rebecca Hiller

Graduate Theses, Dissertations, and Problem Reports (ETD)

Since their introduction to US waters, Silver Carp (Hypophthalmichthys molitrix) and Bighead Carp (H. nobilis) have rapidly spread throughout the Mississippi River basin and its major tributaries, but their invasion has stalled within the Ohio River. Recent research has suggested this slowed spread could be due to a lack of suitable nursery habitat in the Ohio River, affecting recruitment of invasive carp. This study aims to characterize the habitats juvenile carp are utilizing by investigating three main lines of inquiry: that juvenile carp habitat use is limited by (1) the flow regime of the Ohio River …

Novel Phenomena In Chiral And Disordered Crystals, Zachary Louis Romestan

Graduate Theses, Dissertations, and Problem Reports (ETD)

The concept of symmetry is central to our understanding of the physical world. Core symmetries—comprising time reversal, charge conjugation, spatial inversion, and rotation—are integral in maintaining essential conservation laws. They also play a critical role in the manifestation of new quantum phases that arise when these symmetries are disrupted. At the heart of contemporary research in condensed matter physics is the exploration of how basic symmetries interact with material imperfections. This examination delves deeply into the ways that inherent symmetrical properties and structural anomalies within materials influence each other, providing crucial insights into the field. This dissertation presents an investigation …

Prioritizing Amd Impaired Watersheds For Watershed-Scale Restoration Using Multi-Criteria Decision Analysis, James Nicholas Marino

Graduate Theses, Dissertations, and Problem Reports (ETD)

Acid Mine Drainage (AMD) remains a significant environmental challenge in coal-mining and hard rock regions like West Virginia, degrading water quality and ecosystem health. Traditional site-specific remediation efforts often prove inefficient in addressing AMD at large scale. This study explores watershed-scale restoration as a more effective solution, leveraging centralized treatment facilities and multi-source pollution management. This study will follow Multi-criteria Decision Analysis (MCDA), specifically the Analytical Hierarchy Process (AHP), to develop a structured rubric for grading watersheds. The process involves identifying critical criteria, organizing them into a hierarchy, and generating weights for clusters of criteria through collaboration with decision makers. …

Multifaceted Life Skills Training And Job-Orientation Supports For Individuals In Vocational Rehabilitation Programming, Laura R. Mccray

Graduate Theses, Dissertations, and Problem Reports (ETD)

There is growing support for those with an intellectual or developmental disability (IDD) in the transition process and within the workplace, however, there are areas that need to be addressed to facilitate further inclusion and success in this domain. There are structured institutions within the community that extend support for those transitioning out of high school, focusing on aligning with life training and professional skills while promoting societal integration by delivering services directly and avoiding isolation within traditional service environments (Accardo & Whitman, 2011). Growing research highlights the necessity of providing resources that support individuals with intellectual and developmental disabilities …

Experimental And Finite Element Analysis Of Vacuum Infused Frp Composite Π-Joints, Jared Cameron Short

Graduate Theses, Dissertations, and Problem Reports (ETD)

Composite π-joints are valued for their potential to reduce component weight, lower manufacturing costs, and simplify assembly. In aerospace applications, these qualities become even more valuable; however, these advantages must be carefully balanced with the safety requirements. Given the complexity of the π-joint geometry, it is crucial to determine and optimize the mechanical properties to ensure quality, performance, and safety throughout the lifetime of the part.

This thesis aims to investigate the effects of various factors on the mechanical properties of a composite π-joint manufactured using vacuum-assisted resin transfer molding (VARTM) processes. The discussion focuses on the effects of fabric …

Using Visual Prompts To Analyze Ejection Fraction In Echocardiograms, Kevin Reisch

Graduate Theses, Dissertations, and Problem Reports (ETD)

Left ventricular ejection fraction (LVEF) is a critical biomarker for heart failure, but manual estimation from echocardiograms is time-consuming. Artificial intelligence can be used to accelerate this process, allowing clinicians to focus on other critical tasks. Current methods typically train models from scratch on echocardiogram datasets; however, this approach is limited by the scarcity of large medical imaging datasets, which are expensive and difficult to acquire. We present a transfer learning approach that leverages pretrained models from massive datasets, enabling continuous improvement as foundation models advance. Our method employs visual prompting to generate trainable masks for echocardiogram videos, transforming the …

The Effect Of Facial Phenotypes On Differential Performance Of Facial Recognition, Evan R. Garrett

Graduate Theses, Dissertations, and Problem Reports (ETD)

Facial recognition technology is utilized in many facets of life. As the use has become more widespread these systems have improved in reliability and performance approaching the level of human accuracy. With these improvements the problem of bias still remains as a persistent problem. Efforts have been made to minimize the bias prevalent in the systems via studies into various demographic factors, creating training datasets that have a more uniform distribution of subjects, and other methods. As facial recognition is one of the most utilized forms of biometric recognition it is vital to analyze potential causes of bias to help …

Commissioning And Recording Project Of New Works For Saxophone Focused On Promoting Mexican Composers And Educating Future Commissioning Saxophonists, Andres Efrain Santana

Graduate Theses, Dissertations, and Problem Reports (ETD)

This document chronicles my process of commissioning and recording five new works by Mexican composers. To contextualize this experience, I provide a brief introduction of Mexican contemporary music history, an overview of second-hand accounts of the commissioning process, my personal experience of this process, and my assessment of the impact these works could have on the classical saxophone repertoire. As I have reflected on my own experience with historical and contemporary accounts of the commissioning process, it has become clear that personal connections between composers and performers and the patronage or funding linked to those relationships are just as important …

Academic Agency Within The Curricular Reform Of Gateway Stem Courses: A Faculty Perspective, Katie Beck

Graduate Theses, Dissertations, and Problem Reports (ETD)

The research regarding faculty agency during curricular reform is a burgeoning field within higher education as the faculty perspective within the current research concerning curriculum reform is limited. This study seeks to illuminate the faculty perspective of the curricular reform process of gateway STEM courses and how faculty experienced the reform process through a qualitative case study. The site of the case study is a public four-year institution on the eastern coast of the United States that has undergone and continues to undergo significant academic restructuring. The research utilized a structured survey and semi-structured interviews with seven total participants from …

La2nio4+Δ-Based Solid Oxide Electrolysis Cell (Soecs) Electrodes Enhanced With Complex Perovskite Nanocatalyst Processed By Surfactant-Enabled Infiltration, Cole Samuel Klemstine

Graduate Theses, Dissertations, and Problem Reports (ETD)

As the world seeks to reduce its reliance on hydrocarbons, the demand for sustainable hydrogen production methods has become increasingly critical. Hydrogen is a versatile energy carrier that can be produced from various sources, including water, natural gas, and biomass. Replacing the burning of hydrocarbons with hydrogen could significantly reduce greenhouse gas emissions, contributing to global climate goals like those set by the US H2NEW program. The joint technologies of solid oxide fuel and electrolysis cells present the ability to both produce and process clean hydrogen to meet these goals. Development into solid oxide fuel cells has been met with …

Reuse Of Calcium Carbonate (Caco3) Recovered From Discarded Carpets As Filler In Fiber-Reinforced Polymer (Frp) Composites, Roshan Devkota

Graduate Theses, Dissertations, and Problem Reports (ETD)

Over four billion pounds of carpet are discarded annually in the United States, making carpet waste a significant environmental concern. Calcium carbonate (CaCo₃) constitutes up to 45% of the mass of most synthetic carpets. Reusing this CaCo₃ as a filler in the rapidly growing fiber-reinforced polymer (FRP) industry, which is projected to reach USD 10.38 billion, presents a low-cost, practical approach to developing a market-based solution to post-consumer carpet waste.

This study investigates the reuse of CaCo₃ recovered from discarded carpet backing as a filler in FRP composites, focusing on its mechanical viability in comparison to virgin CaCo₃. The methodology …

All-Terrain Vehicle Injuries Among Youth: A Multidimensional Analysis Of Injury Patterns In West Virginia And Safety Laws Across High-Fatality States, Sabrina Chyann Beal

Graduate Theses, Dissertations, and Problem Reports (ETD)

All-terrain vehicles (ATVs) pose significant injury risks, particularly among youth. These powerful machines are widely used across recreational and rural settings. West Virginia consistently ranks among the top five states for ATV-related deaths and injuries. Safety equipment and requirements are often not followed nor enforced, causing children and adolescents to be the most vulnerable group because they tend to not wear safety equipment such as helmets, ride on roadways, carry passengers, and operate oversized ATVS. This study examined ATV injury patterns from the WVU Medicine Trauma Registry and ATV laws across the five states with the highest reported fatalities. This …

Exploring Long-Term Patterns: Black Bass Tournament Fishery And Population Trends In West Virginia's Navigable Rivers, Alex J. Benecke

Graduate Theses, Dissertations, and Problem Reports (ETD)

Black bass Micropterus spp. are popular sport fish in West Virginia’s navigable rivers. In recent years, anglers have expressed concerns about a potential decline in fishery quality. To investigate these claims, we evaluated whether fishery quality has declined compared to earlier periods and whether population trends correspond to angler catch rates. Specifically, we aimed to (1) examine changes in species catch over time and during key periods, such as tournament and spawning seasons; (2) describe the distribution of black bass species across pools and habitat types; and (3) assess the outcomes of previous stocking efforts. To address these objectives, we …

Investigating The Role Of Spinal Motoneuron Organization In Human Motor Control, Rachel I. Taitano

Graduate Theses, Dissertations, and Problem Reports (ETD)

Mechanisms of voluntary motor control are complex and require inputs via cortical centers, peripheral sensory systems, and spinal inputs such as central pattern generators. It is hypothesized that control is simplified via utilization of motor primitives, which may rely on structures within the spinal cord, however this remains unknown in both human and non-human primates. The goal of this dissertation is to characterize muscle activity in the upper extremity in relation to the corresponding anatomical organization of spinal motoneurons to provide insight into how primitives are both organized and activated to produce movement.

The first aim of this work was …

1d Geo-Mechanical Model Analysis Of The Mip 1s And Drilling Process Optimization In The Deep Appalachian Basin, Georges Brown Liwuitekong Dongho

Graduate Theses, Dissertations, and Problem Reports (ETD)

The proposed paper assesses the geological and geomechanical characteristics of the geothermal deep direct-use MIP 1S well in the Appalachian basin. The assessment utilizes a comprehensive suite of well logs, sidewall core analysis, and well injection tests to determine continuous elastic and rock strength properties. Stress and pore pressure profiling are conducted, and a validated 1D-geomechanical model is developed. This model undergoes analysis through wellbore stability assessments and comparisons with drilling events. The 1D-geomechanical model demonstrates a high degree of agreement with wellbore observations, revealing suboptimal execution of drilling practices, particularly utilizing mist air drilling up to 8868 feet. This …

An Integrated Framework For Establishing Long-Term Transportation Management Strategies Promoting Sustainable Urban Growth, M Imtiaz Rahman

Graduate Theses, Dissertations, and Problem Reports (ETD)

Urban land areas are experiencing a more rapid expansion compared to their population growth on a global scale. This phenomenon, known as urban sprawl, is characterized by low-density development in the outskirts of cities. This unplanned urban growth leads to changing urban transportation patterns, posing a threat to sustainable development. In response, government agencies implement growth management practices, with transportation management strategies playing a crucial role in achieving sustainable urban growth. However, developing effective growth management strategies is difficult because of several challenges, including limited understanding of the key influencing factors, the complex interdependencies among these factors, and the uncertainties …

Performance Evaluation Of Composite Utility Structures Under Wildfires And Mitigation Methods, Siddhant Sitoula

Graduate Theses, Dissertations, and Problem Reports (ETD)

The Fiber Reinforced Polymer (FRP) composite utility poles and crossarms have been getting wider attention from the utility industries because of their advantages over the traditional wooden, concrete, and steel poles. Wood is vulnerable to fire, rot, and animal damage. Concrete poles are heavier, increasing both transportation and installation costs of the poles, in addition to limited-service life (40-50 years). Similarly, steel poles have durability and safety concerns because of their inherent corrosive nature and conductivity. These disadvantages are significantly reduced by the use of FRP composites in utility structures because of FRP’s strength, specific gravity, flexibility, non-conductivity and durability …

Interactions Between Myeloid Cells And Neutrophil Extracellular Traps In Pancreatic Ductal Adenocarcinoma, Hillary Gabrielle Pratt

Graduate Theses, Dissertations, and Problem Reports (ETD)

The 5-year-survival rate for pancreatic ductal adenocarcinoma (PDAC) is only 12% due in part to a lack of therapeutic strategies that target the pathophysiology of the disease. The only known curative therapy is surgical resection of the PDAC tumor, but only 20% of patients are eligible at the time of presentation. To improve outcomes for patients, new therapeutic options are needed. The PDAC tumor microenvironment (TME) is uniquely fibrotic and hypoxic, which is in part driven by the immune cell composition in the TME. Myeloid cells are a prominent immune infiltrate within the PDAC TME, so these cells have been …

Engineering Applications Of Artificial Intelligence To Forecast Production Of Shale Wells, Yasir Jassim Alkalby

Graduate Theses, Dissertations, and Problem Reports (ETD)

This study examines the application of artificial intelligence (AI) and supervised machine learning techniques to forecast production from unconventional shale wells, utilizing actual field measurement data over a period of two years. Traditional methods, such as decline curve analysis, offer valuable insights but often fail to fully capture the complex nuances affecting productivity and tend to rely excessively on empirical equations.

In this research, the AI-based Shale Analytics approach, introduced by Mohaghegh in 2017, is employed. This method leverages Big Data Analytics to identify unique patterns from actual field observations, enhancing the evaluation and quantification of various productivity factors, facilitating …

Defining Success For An Introductory Mathematics Non-Stem Pathway Course, Clark D. Metz

Graduate Theses, Dissertations, and Problem Reports (ETD)

The enduring debate surrounding college algebra, traditionally a gateway for STEM pathways, underscores the necessity for curricular evolution in response to the rising popularity of non-STEM majors. This dissertation explores the success of an applied college algebra course designed for non-STEM students. The study aimed to determine whether this alternative course could meet diverse student needs while promoting academic achievement and fostering positive attitudes towards mathematics. Findings revealed through a novel approach of a difference-in-differences analysis that students enrolled in the applied college algebra course exhibited higher pass rates due to the introduction of the new course. The lower failure …