Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

Graduate Theses, Dissertations, and Problem Reports (ETD)

Discipline
Keyword
Publication Year
File Type

Articles 271 - 300 of 2809

Full-Text Articles in Entire DC Network

Examination Of The Time Course Effects Of Electronic Cigarettes On The Thoracic Aorta, Madison Robinson Jan 2024

Examination Of The Time Course Effects Of Electronic Cigarettes On The Thoracic Aorta, Madison Robinson

Graduate Theses, Dissertations, and Problem Reports (ETD)

Endothelial dysfunction is a critical early marker of the pathogenesis of cardiovascular disease and a pathological biomarker in cigarette smokers. Emerging evidence finds similar cardiovascular risks resulting from electronic cigarettes (E-cig) as that seen from smoking. Logically, the time or length of exposure to E-cigs will likely influence the development of vascular dysfunction, however, the length of exposure that causes permanent damage is unknown. The goal of this study was to determine the potential window of chronic E-cig exposure that results in vascular dysfunction, which is marked by endothelial dysfunction, microvascular dysfunction, and stiffening of arteries. Based on prior chronic …


Lgbtq+ Clothing Habits In Appalachia, Kirstyn Korte Jan 2024

Lgbtq+ Clothing Habits In Appalachia, Kirstyn Korte

Graduate Theses, Dissertations, and Problem Reports (ETD)

This study investigated clothing preferences among cisgender queer women within Appalachia and whether they used these preferences to identify their own peers. It also further investigated whether they use clothing as a tool to conceal or reveal their own LGBTQ+ identity. Participants were invited for two interviews each. Between interviews, there was a one-week rumination period for each woman. The women reported themes of using clothing to blend in with their hetero-normative surroundings as they grew up and now lean into a more alternative style and less narrow-minded view of clothing. Perspectives gained from interviewees lined up with current knowledge …


Studies In Nonlinear Chemical Dynamics Of Propagating Precipitation Waves, Md Boshir Ahmed Jan 2024

Studies In Nonlinear Chemical Dynamics Of Propagating Precipitation Waves, Md Boshir Ahmed

Graduate Theses, Dissertations, and Problem Reports (ETD)

This dissertation explores the intricate dynamics of pattern formation in nonlinear chemical systems, specifically focusing on the phenomena of propagating waves and Liesegang patterns in aluminum and zinc hydroxide systems. Through a combination of experimental setups and theoretical models, the study delves into the mechanisms driving these patterns, providing insights into their formation, evolution, and underlying principles.

The research begins with an introduction to nonlinear dynamics and pattern formation, emphasizing the significance of these concepts in understanding complex natural systems. It then moves into a detailed examination of Liesegang bands, discussing classical and reverse systems, and introducing the redissolution process …


Historical Evolution Of The Late 20th-Century Maritime Claims, The Concept Of The Nine-Dash Line, And The Dispute In The South China Sea, Kamil Nowak Jan 2024

Historical Evolution Of The Late 20th-Century Maritime Claims, The Concept Of The Nine-Dash Line, And The Dispute In The South China Sea, Kamil Nowak

Graduate Theses, Dissertations, and Problem Reports (ETD)

This study discusses the origins and development of the South China Sea dispute. It briefly analyzes the overlapping maritime claims, their justifications and legal aspects, and key clashes between the actors across the second half of the 20th century. It uses a historical perspective to assess the present-day conflict. The study discusses the impact of international agreements, national policies, claimants' domestic factors, and external influences connected to the geopolitical situation of the period to determine how they influenced the dispute. The analysis reveals that amidst more pressing global events, the South China Sea issue was frequently overlooked by the international …


Extracting Meaning: Museums, Power, And Shaping The Story Of Coal, Danielle Marie Petrak Jan 2024

Extracting Meaning: Museums, Power, And Shaping The Story Of Coal, Danielle Marie Petrak

Graduate Theses, Dissertations, and Problem Reports (ETD)

Organized into four case studies, this dissertation investigates how longstanding power relationships in the Central Appalachian coalfields have shaped the preservation and presentation of mining history at museums and historic sites. It contributes to scholarship in the fields of public history and Appalachian history by exploring how apolitical, noncritical, and biased narratives at mining history sites have obstructed the public’s acknowledgement of larger forces and systems that govern Appalachian society and often bring harm and misinformation to coalfield residents. To present more exhaustive, nuanced, and innovative interpretations of bituminous coal mining’s past and present, museums and historic sites must redirect …


How Does Locality Impact The Sales And Purchases Of Textiles And Apparel? Exploring Retailers' And Consumers' Perspectives In The U.S., Md Rokibul Hasan Jan 2024

How Does Locality Impact The Sales And Purchases Of Textiles And Apparel? Exploring Retailers' And Consumers' Perspectives In The U.S., Md Rokibul Hasan

Graduate Theses, Dissertations, and Problem Reports (ETD)

The revival of U.S. textile and apparel (T&A) manufacturing is largely attributed to rising consumer interest in locally-produced goods, the pursuit of economic sustainability, and the need to mitigate environmental impacts. This study aims to fill a critical research gap by examining the perceptions and behaviors of both U.S. retailers and consumers regarding locally-made T&A products. Utilizing the theory of planned behavior (TPB) as a theoretical framework, the research explores the constructs of attitudes, subjective norms, and perceived behavioral control to elucidate the factors affecting local T&A sales and purchases. The study employs semi-structured interviews with nine U.S. retailers and …


Parental Socialization Of General And Domain-Specific Self-Control In Adolescents, Matty Johnston Jan 2024

Parental Socialization Of General And Domain-Specific Self-Control In Adolescents, Matty Johnston

Graduate Theses, Dissertations, and Problem Reports (ETD)

Adolescent self-control appears to be an important competency to develop. It has pervasive links with various outcomes (e.g., educational, financial, and interpersonal) both during adolescence and into adulthood (Allemand et al., 2019, Moffitt et al., 2011). Adolescents often report lower self-control compared to adults, although individual levels of self-control vary widely between adolescents (Allemand et al., 2019, Romer et al., 2010). Despite its importance, very little is known about how self-control develops. Thus, the current study aims to examine the relationship between parents’ self-control and that of their teen children. To further understand how adolescents' self-control may be socialized by …


Pepperoni Roll Studios: Prototype Design For Creating And Operating A Podcast And Audio Production Student Organization At West Virginia University, Nicholas Kirk Kratsas Jan 2024

Pepperoni Roll Studios: Prototype Design For Creating And Operating A Podcast And Audio Production Student Organization At West Virginia University, Nicholas Kirk Kratsas

Graduate Theses, Dissertations, and Problem Reports (ETD)

As technology and audience demand change the traditional media landscape, student organizations at the university level, such as West Virginia University’s Student Media, are looking for ways to expand experiential learning opportunities for their students. This professional project seeks to address this need at West Virginia University by proposing and developing a prototype for a stand-alone community of practice for podcasting and audio editing as a student organization under the management of an advisor and professional staff. This project will not only justify the importance and timeliness of an experiential learning environment centered on podcasting but also culminate in generating …


Seeing Red: Hostile Attribution Bias, Aggression, And Antisocial Personality Disorder Traits, Kaley Potter Jan 2024

Seeing Red: Hostile Attribution Bias, Aggression, And Antisocial Personality Disorder Traits, Kaley Potter

Graduate Theses, Dissertations, and Problem Reports (ETD)

Antisocial personality disorder (ASPD) is a destructive and severe mental illness that costs the U.S. trillions of dollars annually. Although ASPD is significantly correlated with acts of aggression, violence, and imprisonment, not all individuals with ASPD are aggressive. In samples without ASPD, increased aggression has been linked to an error in social information processing, which is referred to as hostile attribution bias (HAB).

The current study tested the extent to which HABs, or the tendency to attribute hostility to neutral or ambiguous stimuli, predicted aggression above and beyond ASPD traits in participants with a history of incarceration. Participants (N = …


Reimagining The Refugee Figure: Survival Migration And Its After-Affects, Gabriella Pishotti Jan 2024

Reimagining The Refugee Figure: Survival Migration And Its After-Affects, Gabriella Pishotti

Graduate Theses, Dissertations, and Problem Reports (ETD)

As the refugee crisis continues to worsen, so too will the field of refugee literature continue to expand into new directions to account for shifts in the refugee figure and developing concerns of survival migrant writers. Drawing from the foundational work of scholars such as Sianne Ngai and Sara Ahmed, I use affect theory as an intervention into these contemporary refugee texts to posit a rethinking of how we analyze refugee stories as narratives of crisis. I employ an affective approach to demonstrate how the emergency of forced migration can be narratively depicted in an embodied way that fosters connection …


Rural Student Postsecondary Decision-Making: Navigating Narratives Of The Purpose And Value Of Higher Education, Ashley Renee Leggett-Bradley Jan 2024

Rural Student Postsecondary Decision-Making: Navigating Narratives Of The Purpose And Value Of Higher Education, Ashley Renee Leggett-Bradley

Graduate Theses, Dissertations, and Problem Reports (ETD)

The narrative surrounding the purpose and place of higher education has shifted dramatically over the past few decades, despite the persistent perceptions of the necessity of an educated society. With these shifts and conflicting narratives comes the question of how students are influenced by these narratives as they make their postsecondary decisions. This study seeks to illuminate the unique way that rural students receive, understand, and are influenced by these potentially conflicting narratives through a qualitative multi-site case study. All three sites are located within the North Central Appalachian portion of the state of West Virginia, and encompass a range …


Encouraging Equity Through Rural Elementary Professional Learning, Jana K. Stone Jan 2024

Encouraging Equity Through Rural Elementary Professional Learning, Jana K. Stone

Graduate Theses, Dissertations, and Problem Reports (ETD)

This study employed design-based research to explore the efficacy of professional learning materials and approaches in developing social justice advocacy with rural elementary teachers in Appalachia. Bronfenbrenner’s (2005) bioecological theory and Boler’s (1999) pedagogy of discomfort formed the theoretical framework for the design, implementation, and analysis. Mid-way through the study, Allport’s (1954) contact hypothesis was included to inform the revision of intervention approaches. Four elementary teachers attended seven in-person informational discussion meetings over five months. During this time, these teachers also read two books and completed journal responses and surveys. The qualitative data was analyzed using Braun and Clark’s (2006) …


Leds For Controlled Environment Agriculture: Leveraging Light To Optimize Crops, Tristan D. Sanders Jan 2024

Leds For Controlled Environment Agriculture: Leveraging Light To Optimize Crops, Tristan D. Sanders

Graduate Theses, Dissertations, and Problem Reports (ETD)

Indoor agriculture is a growing industry with many of its benefits being recognized. Light emitting diodes (LEDs) reduce production costs compared to traditional light sources. LEDs emit narrow bandwidths of light that allow growers to easily change the wavelengths plants are being grown under by using different combinations of wavelengths. Manipulating the light that plants are grown under is a method to change their physiology which is the basis of this thesis. The goal of the first two studies was to investigate how different light spectra can be used to enhance the nutrition content, growth, and morphology of kale and …


Assessing The Impact Of Olive Oil And Flaxseed Oil Supplementation On Hypertension And Inflammation In Healthy And At-Risk Adults, Tara Bess Mcnabb Jan 2024

Assessing The Impact Of Olive Oil And Flaxseed Oil Supplementation On Hypertension And Inflammation In Healthy And At-Risk Adults, Tara Bess Mcnabb

Graduate Theses, Dissertations, and Problem Reports (ETD)

Background: Supplementation of olive oil and flaxseed oil and their impacts on hypertension and inflammation have been reported for healthy and hypertensive adults. However, a comprehensive systematic literature review and meta-analysis on the preventive benefit of plant oil supplementation in healthy adults and adults at risk of inflammation inducing hypertension is lacking.

Objective: to evaluate human clinical trials assessing the impact of olive oil and flaxseed oil capsules on systolic blood pressure (SBP) and diastolic blood pressure (DBP) and select inflammatory markers in non-hypertensive and at-risk adults of hypertension.

Data sources: Four databases were searched in October 2023 …


Implementing Unmanned Aerial Vehicles To Collect Human Gait Data At Distance And Altitude For Identification And Re-Identification, Donn E. Bartram Jan 2024

Implementing Unmanned Aerial Vehicles To Collect Human Gait Data At Distance And Altitude For Identification And Re-Identification, Donn E. Bartram

Graduate Theses, Dissertations, and Problem Reports (ETD)

Gait patterns are a class of biometric information pertaining to the way a person moves and poses. Gait information is unique to each person and can be used to identify and reidentify people. Historically, this task has been achieved through the use of multiple ground-based imaging sensors. However, as Unmanned Aerial Vehicles (UAVs) advance, they present the opportunity to evolve the process of persons identification and re-identification. Collecting human gait data using UAVs at distances ranging from 20m to 500m and altitudes ranging from 0m to 120m is a challenging task. The current biometric data collection methods, primarily designed for …


Immune Outcomes Affected By Selection For Parasite Resistance In Katahdin Sheep, Kelsey Lynne Bentley Jan 2024

Immune Outcomes Affected By Selection For Parasite Resistance In Katahdin Sheep, Kelsey Lynne Bentley

Graduate Theses, Dissertations, and Problem Reports (ETD)

Our understanding of the complex connection between selection for parasite resistance and the overall health outcomes in livestock is unclear. This study investigates the impact of post-weaning fecal egg count (PFEC) estimated breeding values (EBV) on health outcomes and immune responses in Katahdin sheep. Selection for PFEC, favoring Low-PFEC lambs, not only affects survivability to weaning but also suggests broader implications for immunity beyond parasite resistance. The effect of PFEC EBV on antibody production in response to vaccination against Clostridium perfringens type C&D and tetanus toxoid (CD&T) revealed a stepwise decrease in immunoglobin (IgG) from Low-PFEC to High-PFEC groups upon …


Effectiveness Of Peer Support Groups For Mothers At Risk For Postpartum Depression, Natalie Paige Gates Jan 2024

Effectiveness Of Peer Support Groups For Mothers At Risk For Postpartum Depression, Natalie Paige Gates

Graduate Theses, Dissertations, and Problem Reports (ETD)

Motherhood requires a role transition, new maternal responsibilities, and changes in everyday life, which can impact the mother’s mental health, possibly leading to postpartum depression. Postpartum depression can, in turn, create additional challenges for the mother in engaging in her daily routines and occupations. Therefore, a peer support group for mothers at risk for postpartum depression was developed in hopes of improving the mothers’ management of routines, ultimately improving maternal mental health. The effectiveness of the peer support group was measured through quantitative and qualitative online self-report surveys, where the mothers reported their current mental health status, self-efficacy, and occupational …


Three Essays On Misinformation, Mistrust And Their Influence On Public Health Policy, Eli Kochersperger Jan 2024

Three Essays On Misinformation, Mistrust And Their Influence On Public Health Policy, Eli Kochersperger

Graduate Theses, Dissertations, and Problem Reports (ETD)

In the first chapter I identify the impact of fentanyl exposure misinformation- namely, the erroneous belief that momentary, passive contact with the potent opioid fentanyl can be seriously harmful- on first responder behavior during overdose events, and on overall opioid-related mortality. I examine changes in opioid-related mortality following one particularly well-covered episode involving an Ohio police officer in 2017, wherein the officer appeared to experience an acute opioid overdose after touching what was believed to be fentanyl. Employing a synthetic differences-in-differences identification strategy, I find areas with greater media exposure to this misinformation exhibit marked increases in opioid overdose deaths; …


Analysis Of Mutations In Protein Kinase Ck2 Linked To Okur-Chung’S Neuropathy, Shivani Maan Jan 2024

Analysis Of Mutations In Protein Kinase Ck2 Linked To Okur-Chung’S Neuropathy, Shivani Maan

Graduate Theses, Dissertations, and Problem Reports (ETD)

The studies described here focus on mutations in protein kinase CK2 linked to ‘Okur-Chung’s Neuropathy’ (OCN), a neurodevelopmental disorder that involves 10 distinct mutations in the catalytic subunit CK2α. It has, however, remained unresolved if these mutations impair CK2α activity or if they also impair association with the regulatory CK2β subunit, which is necessary for assembly of the α2β2 holoenzyme. I describe efforts to resolve these questions for two mutations, Y50S and D175G. The former is thought to reside at the CK2α-CK2β interface, whereas the latter is located proximal to the active site. I therefore hypothesized that Y50S should perturb …


Understanding Learners' Perception Of Virtual Reality-Assisted Learning In Engineering Education, Mohammad Samin Mansur Jan 2024

Understanding Learners' Perception Of Virtual Reality-Assisted Learning In Engineering Education, Mohammad Samin Mansur

Graduate Theses, Dissertations, and Problem Reports (ETD)

Virtual reality (VR)-assisted learning may facilitate an immersive and interactive learning environment and enable learners to explore and interact with learning content at their own pace and interest. However, it is still unknown how well VR is received in engineering learning while empowering autonomy and personalization. The objective of this study is to investigate learners' perceptions of VR-assisted learning in engineering education while allowing learners to learn at their own pace, driven by their personal preference. To this end, experiments were conducted, in which thirty engineering students were recruited and immersed in a VR setting designed to deliver an interactive …


Zoo Communication: A Study Of Stewardship With Animal Conservation In Zoos Across The United States, Abby Rachelle Lester Jan 2024

Zoo Communication: A Study Of Stewardship With Animal Conservation In Zoos Across The United States, Abby Rachelle Lester

Graduate Theses, Dissertations, and Problem Reports (ETD)

This thesis investigates the communication strategies employed by zoo professionals to promote engagement and advanec animal conservation education. Through in-depth interviews with zoo experts, the stidy explores the intricate connections between communication practices and stewardship princliples within zoo facilities. Findings from this study contribute to the understanding of effective communication in the realm of animal conservation, with implications for both zoo practitioners and conservation educators. The study delves into the effective strategies for identifying and fostering relationships with environmental stewards, alongside encouraging their involvement in zoo-based animal conservation initiatives. The theoretical implications highlight gaps in existing models, emphasizing the need …


You Belong With Me: What Communication Professionals Can Learn From Swifties, Rachel Belle Johnson Jan 2024

You Belong With Me: What Communication Professionals Can Learn From Swifties, Rachel Belle Johnson

Graduate Theses, Dissertations, and Problem Reports (ETD)

Pop powerhouse Taylor Swift has managed to create a dedicated fanbase that has the power to disrupt national sporting leagues and boost the American economy. Her Swifties are an exemplar in the world of fandom. Taylor Swift’s online interactions with fans, especially in the early days of her career, are partially responsible for her success in creating and maintaining this fanbase. Using principles of social informational processing theory (SIPT), this research examines what aspects of Taylor Swift’s computer-mediated communication with fans have fostered such intense feelings of community in her fandom of Swifties. Using in-depth interviews to explore the relationships …


The Impact Of Occupational Therapy In Lactation Services, Sarah Adrienne Mcaninch Jan 2024

The Impact Of Occupational Therapy In Lactation Services, Sarah Adrienne Mcaninch

Graduate Theses, Dissertations, and Problem Reports (ETD)

Many benefits to breastfeeding exist for both mothers and infants, yet exclusive breastfeeding rates remain low across the nation. These benefits include decreased chance of infections for infants, low infant mortality, and decreased chances of breast and ovarian cancers for mothers (Binns et al., 2016; CDC, 2023). Education strategies have recently become imperative for health organizations to help mothers sustain their ability to breastfeed within the recommended six-month timeframe. Current literature on education supports that women who receive education at some point in their lactation journey are more likely to reach the six-month period and have more confidence in their …


Estradiol’S Role In Timely Puberty Onset In The Ewe, Eliana Gerardine Aerts Jan 2024

Estradiol’S Role In Timely Puberty Onset In The Ewe, Eliana Gerardine Aerts

Graduate Theses, Dissertations, and Problem Reports (ETD)

In female sheep, the release of gonadotropin-releasing hormone (GnRH) from the hypothalamus triggers luteinizing hormone (LH) to be released from the pituitary. Luteinizing hormone, in turn, acts on the ovaries to elicit estradiol (E2) release. E2 acts in a negative feedback manner to control the amount of LH released. The increase in LH release that drives puberty onset results from a decrease in sensitivity to E2 as the animal ages. However, the neural mechanisms mediating this change in sensitivity are not known, as is where in the hypothalamus E2-negative feedback occurs. In the arcuate …


Using Critical Place-Based Pedagogy To Build A Bridge Between College Students’ Home Literacies And Their Academic Literacies In A Composition Class In West Virginia, Michael Vozniak Jan 2024

Using Critical Place-Based Pedagogy To Build A Bridge Between College Students’ Home Literacies And Their Academic Literacies In A Composition Class In West Virginia, Michael Vozniak

Graduate Theses, Dissertations, and Problem Reports (ETD)

This dissertation explores the use of place-based pedagogy as a tool for teaching for transfer in a college composition class in West Virginia. Although existing composition scholarship indicates that themed classes (such as a place-based class) are unlikely to facilitate transfer among the students, this is mostly due to instructors of themed classes not explicitly teaching for transfer. The literature suggests that the most effective way to facilitate transfer is to encourage students to reflect on how what they learned in one situation is similar to and different from what they need to learn in another situation. The aim of …


Evaluations Of Frp Composite Coupons Under Impact And Puncture, Lekhnath Bhandari Jan 2023

Evaluations Of Frp Composite Coupons Under Impact And Puncture, Lekhnath Bhandari

Graduate Theses, Dissertations, and Problem Reports (ETD)

Evaluations of FRP Composite Coupons Under Impact and Puncture

Lekhnath Bhandari

Railroad tank cars are the main mode of transportation for carrying flammable liquids and other hazardous materials, in any mode of ground transportation system. These tank cars, if punctured during derailments may explode releasing large amounts of hazardous materials and posing serious threats to human life and leading to economic losses. To minimize such catastrophes, in 2015, United States Department of Transportation (USDOT) proposed to improve the thermal and puncture performances of these tank cars and introduced two new design specifications: DOT-117 and DOT-117R. Tank cars with 9/16 inches …


Estimate Of The Random Match Frequency Of Acquired Characteristics In A Forensic Footwear Database, Alyssa N. Smale Jan 2023

Estimate Of The Random Match Frequency Of Acquired Characteristics In A Forensic Footwear Database, Alyssa N. Smale

Graduate Theses, Dissertations, and Problem Reports (ETD)

When analyzing footwear impression evidence, one of the goals of an examiner is to determine if an exemplar shoe could be the source of an impression found at a crime scene. This opinion is based on an assessment of the similarity of class characteristics and randomly acquired characteristics (RACs) between the known and questioned impressions, as well as the rarity of the observed characteristics. The primary aim of this research was to estimate the random match frequency of randomly acquired characteristics (RAC-RMF) within a forensic footwear database to determine the frequency of RACs with geometric similarity occurring in the same …


Levantine Immigration And Community Building In Charleston, West Virginia, 1900-1930, George P. Jacobs Ii Jan 2023

Levantine Immigration And Community Building In Charleston, West Virginia, 1900-1930, George P. Jacobs Ii

Graduate Theses, Dissertations, and Problem Reports (ETD)

Immigrants from the Levant, a region of the middle east made up of Syria, Lebanon, Jordan, and Palestine, settled in the United States in large numbers between 1890 and 1920. Many eventually decided to make Charleston, West Virginia their permanent home. When they arrived in Charleston, most Levantine immigrants worked as peddlers, selling modern wares and household goods to families that needed them. This research explains the context for this immigration wave, the important economic niche Levantine immigrants satisfied in the developing economy of southern West Virginia, and how over time Charleston’s Levantine community contributed significantly to the city’s culture.


Attachment Issues: Microbes, Minerals, And The Persistence Of Soil Organic Matter, Md Shafiul Islam Rion Jan 2023

Attachment Issues: Microbes, Minerals, And The Persistence Of Soil Organic Matter, Md Shafiul Islam Rion

Graduate Theses, Dissertations, and Problem Reports (ETD)

The remnants of microorganisms are now understood to account for the majority of organic matter in many mineral soils. Despite the significance of this microbial necromass for soil carbon storage, we know relatively little about how the traits of microorganisms interact with soil minerals to determine the stability of microbe derived carbon in soil. Soil minerals differ in their surface area and chemistry potentially influencing microbial attachment, biofilm formation, and the persistence of microbial necromass. To address this knowledge gap, we grew twelve bacterial species from four broad groups of varying cell wall morphology (Gram positive, Gram negative, filamentous actinobacteria, …


Specialized Metabolism In Retina, Retinal Pigmented Epithelium, And Testis, Siyan Zhu Jan 2023

Specialized Metabolism In Retina, Retinal Pigmented Epithelium, And Testis, Siyan Zhu

Graduate Theses, Dissertations, and Problem Reports (ETD)

The retina and its neighboring retinal pigmented epithelium (RPE) are high energy-demanding and metabolically active tissues with specialized and complementary metabolism. They are metabolically interdependent and impact each other’s viability. Interestingly, many of the metabolic features in the retina and RPE are shared with the testis. For example, testis is also energy costly due to continuous sperm differentiation and it has similar metabolic inter-dependence between different testis cells. Both the retina and testis are vulnerable to mitochondrial metabolic impairments.

We conducted three research projects to understand 1) the nutrient utilization and communication in retina and RPE; 2) The profiling of …