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The Role Of Geography, Demographics, Bandwidth Speed And Internet Availability In Rural West Virginia Communities: A Multiple Case Study Of The 2012 Cards Of Hope Fundraiser, Rebecca Diehm May 2013

The Role Of Geography, Demographics, Bandwidth Speed And Internet Availability In Rural West Virginia Communities: A Multiple Case Study Of The 2012 Cards Of Hope Fundraiser, Rebecca Diehm

Graduate Theses, Dissertations, and Problem Reports (ETD)

Today, social media has become a popular public relations tool in the promotion of campaigns and fundraisers. While this new addition may be a key tool in the promotion of certain fundraisers and campaigns, this study was designed to focus on what public relations methods successfully promote events, campaigns and fundraisers in rural areas, such as those in West Virginia. The objective of this master's thesis is to support the notion that press releases are still the foundation of public relations methods not only in West Virginia, but in rural communities throughout the United States. In order to support this …


Distributed Location Estimation Of A Moving Target Characterized By A Spatial Poisson Field, Fathi Masoud May 2013

Distributed Location Estimation Of A Moving Target Characterized By A Spatial Poisson Field, Fathi Masoud

Graduate Theses, Dissertations, and Problem Reports (ETD)

Wireless Sensor Networks (WSNs) are traditionally employed to collect spatial and temporal data characterizing various events. These data are then used to solve inference problems such as object detection, counting, classification, estimation and tracking. Distributed solutions provided by WSNs are often cost effective and characterized by high performance indices.;In this work, we model and simulate a distributed sensor network composed of radiation detectors and analyze its ability to make inferences. Radiation detectors are deployed over a known area. A radiological point source is positioned in the interior of the area. Detectors take measurements of the field generated by the point …


Parent Civic Behavior And Observed Civic Messages: Associations With Adolescent Civic Behavior And Prioritization, Benjamin J. Oosterhoff May 2013

Parent Civic Behavior And Observed Civic Messages: Associations With Adolescent Civic Behavior And Prioritization, Benjamin J. Oosterhoff

Graduate Theses, Dissertations, and Problem Reports (ETD)

The current study employed observational and multi-informant survey methodology to explore associations among parents' civic behaviors, observed parent and adolescent messages about civic obligation, and adolescents' civic behavior and prioritization (should) judgments. A sample of 160 adolescents (Mage = 14.42, range = 12-18) and their parents (144 mothers and 52 fathers), participated in video-recorded, structured, dyadic interaction tasks in which they discussed citizenship and civic duty. Parents and adolescents also completed questionnaires assessing civic behavior and civic prioritization judgments. Within distinct civic activities, parents' report of civic behavior was positively associated with adolescents' report of civic behavior and prioritization judgments. …


Evaluating The Intra-Variability And Inter-Variability Of Fibers In Cotton T-Shirts Using Microspectrophotometry, Brianne Miller May 2013

Evaluating The Intra-Variability And Inter-Variability Of Fibers In Cotton T-Shirts Using Microspectrophotometry, Brianne Miller

Graduate Theses, Dissertations, and Problem Reports (ETD)

The objective of this study was to evaluate and compare the differentiation of cotton fibers by the means of intra-garment and inter-garment comparison while utilizing Microspectrophotometry. Five different colors of cotton fibers were used: gold, kelly green, orange, red and royal. Ten t-shirts of each color were used in this study. Phase I of this study involved using the CRAICRTM QDI QDS II(TM) Stereomicrospectrophotometer to produce a spectrum of the front, back, sleeve and armpit of the t-shirt. These sections were then compared to the color chips in the Munsell Book of Color by observing them with the naked eye. …


Predictors Of Distress During The Breast Diagnostic Period, Mariann M. Harding May 2013

Predictors Of Distress During The Breast Diagnostic Period, Mariann M. Harding

Graduate Theses, Dissertations, and Problem Reports (ETD)

Breast cancer is the most common cancer diagnosed in women and the leading cause of cancer deaths among women worldwide (Warner, 2011). Mortality from breast cancer in the United States has been decreasing in part due to advances in therapy and the detection of the disease at earlier stages. As a result, more than 1.6 million U.S. women will undergo a breast biopsy in 2013 with approximately 232,340 of these being diagnosed with cancer. Although distress in women undergoing a breast diagnostic evaluation has been recognized as having the potential to alter treatment outcomes in those diagnosed with cancer, few …


Differences In Early Childhood Environmental Rating Scale Scores In Collaborative And Non-Collaborative West Virginia Pre-K Classrooms Located In Child Care Facilities, Jessica S. Day May 2013

Differences In Early Childhood Environmental Rating Scale Scores In Collaborative And Non-Collaborative West Virginia Pre-K Classrooms Located In Child Care Facilities, Jessica S. Day

Graduate Theses, Dissertations, and Problem Reports (ETD)

Quality of pre-k collaborative and non-collaborative classrooms was investigated for differences in environmental quality between the two types of classrooms. Data was collected through the West Virginia Department of Health and Human Resources grant titled, "Quality Rating and Improvement for West Virginia Child Care." Quality was measured using the Early Childhood Environmental Rating Scale-Revised (ECERS-R), which has 43 items across seven subscales: Space and Furnishings, Personal Care Routines, Language-Reasoning, Activities, Interaction, Program Structure, and Parents and Staff. Thirty-six pre-k collaborative programs participated and 136 non-collaborative programs participated in the study. Non-collaborative pre-k classrooms had lower mean scores on all subscales …


The Effects Of Currency And Imports Restrictions On Luxury Advertising In Argentina: Content Analysis Of Ads In Argentine Fashion Magazines, Juan F. Mundel May 2013

The Effects Of Currency And Imports Restrictions On Luxury Advertising In Argentina: Content Analysis Of Ads In Argentine Fashion Magazines, Juan F. Mundel

Graduate Theses, Dissertations, and Problem Reports (ETD)

While many scholars have examined the relationships between public policies and advertising, few have studied such relationships in Latin America. This study explores how the limitations on foreign exchange transactions in Argentina affect the advertising strategies implemented by luxury brand advertising. A content analysis of 398 luxury brand ads placed in fashion magazines in Argentina was conducted to investigate changes in the luxury ads in the wake of the currency and import restrictions in Argentina. The analysis indicates that, during the restrictions, ads were less likely to convey strong emotional messages than before. Also, the result suggests that the creative …


Remembering 1989: Post-Communist Commemorations In Berlin And Warsaw, Kyle Jordan Meadows May 2013

Remembering 1989: Post-Communist Commemorations In Berlin And Warsaw, Kyle Jordan Meadows

Graduate Theses, Dissertations, and Problem Reports (ETD)

Germany and Poland since 1989 have become lands of contested memory, as reflected by their attempts to commemorate the series of reforms that led to the end of their Communist regimes. This study is an attempt to analyze the various modes of commemoration dedicated to the transition from communism that have taken place in the intervening years between 1989 and the present. Included amongst these efforts are events occurring in public spaces, such as official remembrance ceremonies like Berlin's Festival of Freedom in 2009, physical monuments, and institutions dedicated to preserving memory, specifically the Gauck Authority in Germany and the …


Appalachian Alter-Natives: The Back-To-The-Land Migration And Community Change In Appalachia, 1970--2000, Jinny A. Turman May 2013

Appalachian Alter-Natives: The Back-To-The-Land Migration And Community Change In Appalachia, 1970--2000, Jinny A. Turman

Graduate Theses, Dissertations, and Problem Reports (ETD)

Beginning in the late 1960s and continuing through the 1970s, thousands of people migrated from America's cities to the countryside to establish communes and independent homesteads on small plots of land. By working the land they hoped to achieve autonomy, self-sufficiency, and closeness with nature. Cheap land, mild climate, beautiful scenery, and folk culture drew many of these predominately young, white, well educated, and affluent migrants to Appalachia. During the earliest years of the back-to-the-land migration suspicion and occasionally conflict surfaced as natives and newcomers navigated different lifestyle preferences and worldviews, for many of the back-to-the-landers, or "alter-natives," had identified …


How Do They Think Differently?: A Social Media Advertising Attitude Survey On Chinese Students In China And Chinese Students In America, Anan Wan May 2013

How Do They Think Differently?: A Social Media Advertising Attitude Survey On Chinese Students In China And Chinese Students In America, Anan Wan

Graduate Theses, Dissertations, and Problem Reports (ETD)

This study explored whether Chinese students in both China and in America had different attitudes toward social media advertising, and how their attitudes are different, through a survey of Chinese students in these two countries. The survey determined how they used social media, whether the different social media networks in the two countries affected their social media use, and what their attitudes are about social media advertising in terms of sources, content, and level of trustworthiness. It also tested the relationship between the students' the social media diet (amount, frequency, and duration) and attitude toward social media advertising.


Do Forensic Interviewing Methods Or The Presentation Of Research Findings Effect Juror's Perceptions Of Child Witnesses?, Pamela Tessier Jan 2013

Do Forensic Interviewing Methods Or The Presentation Of Research Findings Effect Juror's Perceptions Of Child Witnesses?, Pamela Tessier

Graduate Theses, Dissertations, and Problem Reports (ETD)

It is not uncommon for children to be called to testify as eyewitnesses in court cases. In cases of child sexual abuse, children are often the only witness to the crime and are thus relied upon for truthful testimony in the case. Given a number of different forensic interviewing techniques, jurors may find themselves looking at some interview techniques as more credible and truth-inducing than others. This study aimed to find how much, if any, influence the type of interview used with the child has on the individual juror. It also aimed to assess the effect that presenting research findings …


Secondary Coal Seam As A Barrier To Co2 Leakage, Zainab Sahib Jawad Jan 2013

Secondary Coal Seam As A Barrier To Co2 Leakage, Zainab Sahib Jawad

Graduate Theses, Dissertations, and Problem Reports (ETD)

Geologic formations, such as unmineable or depleted coal seams, are considered to be potential reservoirs for CO2 storage. Coal seams are naturally fractured reservoirs which consist of primary and secondary cleat networks. During production, coalbed methane (CBM) is desorbed from the coal surface and flows through the cleat network. When carbon dioxide (CO2) is injected into a coal seam, large amount of the injected CO2 is sorbed on the coal surface due to the greater affinity of CO2 towards coal than methane. This provides two advantages: potential CO 2 storage and enhanced coalbed methane recovery. Several pilot studies have been …


Swedish Legislation Targeting Trafficking For Sexual Exploitation And The Possibilities For Implementation In Estonia, Jennifer E. Lyall Jan 2013

Swedish Legislation Targeting Trafficking For Sexual Exploitation And The Possibilities For Implementation In Estonia, Jennifer E. Lyall

Graduate Theses, Dissertations, and Problem Reports (ETD)

Human trafficking is a human rights problem affecting all regions of the world. Various approaches have been utilized in attempts to eliminate the trade in human beings. In 1999, Sweden instituted a law to ban the purchase of sexual services, viewing prostitution as inherently violent and a contributing factor of human trafficking for sexual exploitation. This thesis determines that banning the purchase of sex is a legitimate and effective measure in combatting human trafficking for sexual exploitation. This thesis then discusses the Estonian sex industry and the possibilities for implementation of a similar sex purchase ban. Obstacles include Estonia's historical …


Reservoir Simulation For Production Of Methane From Gas Hydrate Reservoirs Using Carbon Dioxide/Carbon Dioxide+Nitrogen By Hydrateressim., Nagasree Garapati Jan 2013

Reservoir Simulation For Production Of Methane From Gas Hydrate Reservoirs Using Carbon Dioxide/Carbon Dioxide+Nitrogen By Hydrateressim., Nagasree Garapati

Graduate Theses, Dissertations, and Problem Reports (ETD)

Natural gas hydrate reservoirs are likely to contain more carbon than in all other fossil fuel reserves combined. Different techniques currently being proposed for production of CH4 from hydrate deposits include depressurization, thermal stimulation and inhibitor injection. These processes involve the dissociation of hydrate and the release of significant volumes of water, which may cause geomechanical stress on the reservoir leading to subsidence. A series of experimental studies over the decade reviewed the feasibility of using CO2/CO2+N2 gas mixtures to recover CH4 gas from the hydrates, which serves the dual purpose of CO2 sequestration and production of CH4 while maintaining …


The Production, Value, And Reduction Responsibility Of Carbon Emissions Through Electricity Consumption Of Manufacturing Industries In South Korea And Thailand, Medhawin Kitikun Jan 2013

The Production, Value, And Reduction Responsibility Of Carbon Emissions Through Electricity Consumption Of Manufacturing Industries In South Korea And Thailand, Medhawin Kitikun

Graduate Theses, Dissertations, and Problem Reports (ETD)

This dissertation provides a new method of measuring efforts by manufacturing industries to reduce their emissions by curtailing electricity consumption. Employing comprehensive firm-level data from the National Manufacture Annual Surveys of South Korea and Thailand, I construct the measure from estimates of revenue functions by industry. The data consists of firms from more than 20 industries in each year from 1982 to 2005 for Korea and from 2001 to 2008 for Thailand. With a total of more than two million observations, I estimate revenue functions for each industry and year. Here, I use three inputs: number of employees(L), fixed asset …


A Survey Of Journalism Schools' Online Publication Of Student Content, Sarah E. Moore Jan 2013

A Survey Of Journalism Schools' Online Publication Of Student Content, Sarah E. Moore

Graduate Theses, Dissertations, and Problem Reports (ETD)

Journalism in the digital age has changed dramatically as the needs and demands of journalism consumers have changed. In turn, the institutions preparing journalists to enter the field must adapt their methods. How can a school of journalism effectively integrate the web into their daily practices and equip students for post-graduation employment through the publication of an online magazine? This paper explores the broadly divergent methods and philosophies of three journalism schools and offers suggestions for schools developing their own online publication based on these observations.


The Effects Of Student Behavior Alteration Techniques On Student Motives To Communicate, Student Talk, And Student Learning, Christopher J. Claus Jan 2013

The Effects Of Student Behavior Alteration Techniques On Student Motives To Communicate, Student Talk, And Student Learning, Christopher J. Claus

Graduate Theses, Dissertations, and Problem Reports (ETD)

This dissertation addressed the effects of students' perceived effectiveness of and likelihood to use student behavior alteration techniques (BATs) on students' motives to communicate with their instructors, student talk (i.e., willingness to talk, out-of-class communication), and student learning (i.e., cognitive learning, affective learning, state motivation, and student communication satisfaction). Results revealed that student perceived effectiveness of, and likelihood to use, student BATs did not influence, student talk or student learning, but indicated some significant relationships with the students' motives to communicate with their instructors. Specifically, the relational, functional, participatory, and sycophancy motives were generally related to the perceived likelihood to …


Selling 'Fracking': Legitimation Of High Speed Oil And Gas Extraction In The Marcellus Shale Region, Jacob R. Matz Jan 2013

Selling 'Fracking': Legitimation Of High Speed Oil And Gas Extraction In The Marcellus Shale Region, Jacob R. Matz

Graduate Theses, Dissertations, and Problem Reports (ETD)

The advent of horizontal hydraulic fracture drilling, or 'fracking,' a technology used to access oil and natural gas deposits, has allowed for the extraction of deep, unconventional shale gas and oil deposits in various shale seams throughout the United States and world. One such shale seam, the Marcellus shale, extends from New York State, across Pennsylvania, and throughout West Virginia, where shale gas development has significantly increased within the last decade. This boom has created a massive amount of economic activity surrounding the energy industry, creating jobs for workers, income from leases and royalties for landowners, and profits for energy …


Characterization And Application Of Self-Assembled Nano-Materials For Fluid Steering And Separation In Microfluidics, Xingwei Wu Jan 2013

Characterization And Application Of Self-Assembled Nano-Materials For Fluid Steering And Separation In Microfluidics, Xingwei Wu

Graduate Theses, Dissertations, and Problem Reports (ETD)

Aqueous phospholipid preparations comprised of 1,2-dimyristoyl- sn-glycero-3- phosphocholine (DMPC) and 1,2-dihexanoyl-sn-glycero-3-phosphocholine (DHPC) are prevalent materials for biological characterization. The viscosity behavior of DMPC/DHPC was characterized as a function of q value (q= [DMPC]/[DHPC] ), hydration as well as temperature firstly on bench-top and then in microfluidic chip. The rheology of 20% phospholipid preparations of [DMPC]/[DHPC] = 2.5 reveals that, under conditions utilized for fluid steering, the materials are shear-thinning power-law fluids with a power-law index ranging from 0.30 through 0.90. Phospholipid preparations are utilized to steer fluids in microfluidic chips and support hydrodynamic delivery of sample across a double T …


Determining Faculty Perception Of Ownership Rights Of Online Course Content In Higher Education, Carrie J. White Jan 2013

Determining Faculty Perception Of Ownership Rights Of Online Course Content In Higher Education, Carrie J. White

Graduate Theses, Dissertations, and Problem Reports (ETD)

With the ever increasing growth in the number of online courses offered by institutions of higher education, determining ownership of the content of these courses is becoming an important consideration. Many institutions have intellectual property policies in place that are either vague, outdated or non-existent when determining copyright ownership to online courses. Faculty members who are creating these courses are many times investing their own intellect into the course content, which would traditionally invoke copyright ownership over that content. However, courses being offered to students in an online format have created some confusion as to ownership rights over those courses. …


Network Dynamics, Synchronization, And Self-Propelled Particles In Chemical Systems, Hua Ke Jan 2013

Network Dynamics, Synchronization, And Self-Propelled Particles In Chemical Systems, Hua Ke

Graduate Theses, Dissertations, and Problem Reports (ETD)

Neural networks are a class of biological networks of great importance. They are a key component of the central nervous system that coordinates body functions. The exploration of the detailed mechanism of biological neural networks remains extremely active. Inspired by the structure of biological neural networks, artificial neural networks have been designed to solve a variety of problems in pattern recognition, prediction, optimization and control. However, few studies have been reported that explore the dynamics of biological neural networks using chemical systems. As part of this thesis, an experimentally trainable network based on the photosensitive Belousov-Zhabotinsky reaction is developed, where …


Characterization Of The Unique Flagellar Hook Structure Of The Spirochetes Borrelia Burgdorferi And Treponema Denticola, Kelly Ann Heintzelman Miller Jan 2013

Characterization Of The Unique Flagellar Hook Structure Of The Spirochetes Borrelia Burgdorferi And Treponema Denticola, Kelly Ann Heintzelman Miller

Graduate Theses, Dissertations, and Problem Reports (ETD)

The long-term goal of this project is to better understand Borrelia burgdorferi and Treponema denticola motility as it relates to pathogenesis. The structure of the spirochete periplasmic flagella is unique when compared to externally located flagella. One unusual characteristic is the flagellar hook, which serves as a universal joint coupling rotation of the membrane bound motor complex to the flagellar filament. The hook is composed of approximately 120 FlgE monomers, and in bacteria with externally located flagella, these structures readily disassociate into monomers (~50 kDa) when treated with heat and detergent. However, in spirochetes the FlgE monomers form a large …


Characterizing The Variability In Particulate Mass Emissions From Current Model Year Diesel And Natural Gas Engines, Pragalath Thiruvengadam Padmavathy Jan 2013

Characterizing The Variability In Particulate Mass Emissions From Current Model Year Diesel And Natural Gas Engines, Pragalath Thiruvengadam Padmavathy

Graduate Theses, Dissertations, and Problem Reports (ETD)

The objective of this study is to discern and characterize the factors contributing to the variability in Particulate Matter (PM) mass emissions from current model year diesel and natural gas engines observed during in-use chassis dynamometer testing and compare it with an alternate method of mass measurement involving instantaneous particle size distribution and number count. The study involves the analysis of engine and chassis dynamometer data collected from different engine technologies and chassis dynamometer test cycles in order compare the variability in gravimetric PM mass as well as the PM mass estimated by number-concentration.;PM and oxides of nitrogen (NOx) have …


Tuning The Electrical And Thermal Conductivities Of Thermoelectric Oxides Through Impurity Doping, Maria A. Torres Arango Jan 2013

Tuning The Electrical And Thermal Conductivities Of Thermoelectric Oxides Through Impurity Doping, Maria A. Torres Arango

Graduate Theses, Dissertations, and Problem Reports (ETD)

Waste heat and thermal gradients available at power plants can be harvested to power wireless networks and sensors by using thermoelectric (TE) generators that directly transform temperature differentials into electrical power. Oxide materials are promising for TE applications in harsh industrial environments for waste heat recovery at high temperatures in air, because they are lightweight, cheaply produced, highly efficient, and stable at high temperatures in air. Ca3Co4O9(CCO) with layered structure is a promising p-type thermoelectric oxide with extrapolated ZT value of 0.87 in single crystal form [1]. However the ZT values for the polycrystalline ceramics remain low of ∼0.1-0.3. In …


Attitude Of Saudi Female Math Teachers Toward Integrating E-Learning In Teaching Math At High Schools In Saudi Arabia, Aishah M. Albalawi Jan 2013

Attitude Of Saudi Female Math Teachers Toward Integrating E-Learning In Teaching Math At High Schools In Saudi Arabia, Aishah M. Albalawi

Graduate Theses, Dissertations, and Problem Reports (ETD)

Leaders in government and education have launched an extensive program to reform general education in Saudi Arabia. This initiative was designed to achieve many goals with a major emphasis being the enhancement of the Saudi curriculum to take advantage of the use of technology to improve education. A goal of this project was for e-learning to be a part of public education in an attempt to improve student learning and to make education accessible to all citizens.;This study was designed to examine high school female math teachers' attitudes toward the use of e-learning in teaching mathematics in selected high schools …


Effects Of Stereotype Threat On Adolescents' Math And Visual-Spatial Performance., Lisa M. Didonato Jan 2013

Effects Of Stereotype Threat On Adolescents' Math And Visual-Spatial Performance., Lisa M. Didonato

Graduate Theses, Dissertations, and Problem Reports (ETD)

Recent research suggests that the gender gap in math performance is closing (Else-Quest, Hyde, & Linn, 2010; Hyde, Lindberg, Linn, Ellis, & Williams, 2008). However, negative stereotypes about girls’ math abilities are still widely held (Bhanot & Jovanovic, 2005; Bleeker & Jacobs, 2004). The gender gap in visual-spatial skills, or the ability to reason about and manipulate mental pictures, still exists in that boys outperform girls on visual-spatial tasks. The current study drew from literature on stereotype threat (i.e., the risk of confirming negative stereotypes about a specific group; Steele, 1997) to investigate the impact of negative math stereotypes on …


Evaluating Biodegradable Containers As Alternatives To Plastic Pots, Renee L. Conneway Jan 2013

Evaluating Biodegradable Containers As Alternatives To Plastic Pots, Renee L. Conneway

Graduate Theses, Dissertations, and Problem Reports (ETD)

Marked improvements in the sustainability of the horticulture industry have occurred over the last few decades. Movement towards better management practices in areas such as pesticide (IPM), fertilizer application and water usage characterizes today's industry. However, several obstacles have to be overcome for true long-term sustainability of the ornamental horticulture industry. One of these obstacles is the abundant use of plastics in the horticulture industry. This research focused on reducing the industry's plastic waste stream by evaluating the effects of biodegradable pots on plant growth parameters and substrate chemistry, as well as characteristics of biodegradable pots such as strength and …


Beaumont Glass Site In Morgantown, Wv. Sustainable Urban Redevelopment Through Interpretive Design, Brownfield Reclamation And Mixed Uses., Maria Juliana Lloreda Jan 2013

Beaumont Glass Site In Morgantown, Wv. Sustainable Urban Redevelopment Through Interpretive Design, Brownfield Reclamation And Mixed Uses., Maria Juliana Lloreda

Graduate Theses, Dissertations, and Problem Reports (ETD)

This thesis project consists of a design approach to the former Beaumont Glass site and the adjacent sites, a total of 14.6 acres. The city of Morgantown and its downtown area are in need of demonstrations of sustainable development practices and mixed use design. The project design and development focus on site inventory and analysis, historic quality of the site, needs of the community, and stakeholder expectations. The applied design strategies are based on sustainable development, interpretive design, brownfield reclamation, phytoremediation technologies, and stormwater management. The vision of this project is the creation of an overall conceptual masterplan based on …


Evaluation Of A Pilot Project To Validate Self-Reported Weights In Adult Patients Undergoing Surgical Interventions., Joanna Fletcher Jan 2013

Evaluation Of A Pilot Project To Validate Self-Reported Weights In Adult Patients Undergoing Surgical Interventions., Joanna Fletcher

Graduate Theses, Dissertations, and Problem Reports (ETD)

Many adults are unaware of their actual body weight, and those who are aware have a tendency to inaccurately report. Anesthetic drugs, like many other drugs, are weight based, some on ideal and some on actual body weight, depending upon the drug. There is a risk of inaccurately dosing medications during the anesthetic event if the medications are dosed based upon an inaccurate body weight. Literature indicates that self-reported patient weights are inaccurate for many reasons. Additionally, estimates of patient weight by healthcare providers are inaccurate. The majority of drugs used in anesthesia are weight based. It is very clear …


The Role Of Focal Adhesion Kinase In Nonmuscle Cell Contraction, Kimberly M. Arnold Jan 2013

The Role Of Focal Adhesion Kinase In Nonmuscle Cell Contraction, Kimberly M. Arnold

Graduate Theses, Dissertations, and Problem Reports (ETD)

Focal adhesions are specialized cell contact sites of distinct molecular composition and structure that bridge the actin cytoskeleton to the extracellular matrix and provide for efficient bidirectional transmission of biochemical and mechanical signals between the intra- and extracellular compartment. Many proteins within the focal adhesion have been discovered to be an integral component of the adhesion structure and function; however, a key molecule in the organization and physiological activity of focal adhesions is focal adhesion kinase (FAK). FAK is a nonreceptor tyrosine kinase that is essential for cell processes including cell migration, growth, and survival. Due to its connection between …