Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Social and Behavioral Sciences (469)
- Medicine and Health Sciences (458)
- Life Sciences (328)
- Engineering (283)
- Psychology (208)
-
- Physical Sciences and Mathematics (137)
- Education (129)
- Arts and Humanities (118)
- Public Health (81)
- Nursing (79)
- Civil and Environmental Engineering (58)
- Diseases (57)
- Dentistry (56)
- Communication (55)
- Medical Sciences (55)
- Clinical Psychology (54)
- Animal Sciences (53)
- Environmental Sciences (53)
- Mechanical Engineering (51)
- Rehabilitation and Therapy (51)
- Medical Specialties (50)
- Business (45)
- Economics (44)
- Operations Research, Systems Engineering and Industrial Engineering (42)
- Sociology (42)
- Chemistry (41)
- Higher Education (41)
- Biochemistry, Biophysics, and Structural Biology (40)
- Forest Sciences (39)
- Health Psychology (38)
- Keyword
-
- Mechanical engineering (148)
- Clinical psychology (132)
- Public health (90)
- Forestry (68)
- Nutrition (66)
-
- Behavioral psychology (65)
- Animal sciences (63)
- Developmental psychology (63)
- Higher education (63)
- Nursing (62)
- Environmental engineering (57)
- Electrical engineering (51)
- Environmental science (49)
- Industrial engineering (49)
- Kinesiology (48)
- Aquatic sciences (47)
- Social psychology (47)
- Civil engineering (45)
- Dentistry (45)
- Ecology (44)
- Educational psychology (44)
- Economics (42)
- Agricultural education (40)
- Education (40)
- Microbiology (40)
- Mining engineering (40)
- Physical education (39)
- Automotive engineering (38)
- Physiology (38)
- West Virginia (37)
- Publication Year
- File Type
Articles 931 - 960 of 5148
Full-Text Articles in Entire DC Network
Mtdna Heteroplasmy In Hair Shafts Versus Buccal Swabs For Forensic Applications, Sara R. Bodnar
Mtdna Heteroplasmy In Hair Shafts Versus Buccal Swabs For Forensic Applications, Sara R. Bodnar
Graduate Theses, Dissertations, and Problem Reports (ETD)
Mitochondrial DNA (mtDNA) analysis has several forensic applications such as criminal investigations, identification of human remains, and missing person investigations. It is also the only type of DNA that is available from certain sample types such as hair shafts. The presence of mtDNA heteroplasmy within and between tissue types can lead to mtDNA sequence differences when comparing samples originating from the same individual. Studies on mtDNA heteroplasmy are increasingly being carried out for their implications in forensic interpretation of mtDNA sequences. Specifically, mtDNA in buccal swabs compared to hair samples from one individual may show differences in sequence due to …
Framing Fashion Sustainability In Fashion Magazines, Kristen Ann Mohammadi
Framing Fashion Sustainability In Fashion Magazines, Kristen Ann Mohammadi
Graduate Theses, Dissertations, and Problem Reports (ETD)
This study explores the framing, dominant frame, story focus, and tone of sustainable fashion coverage in prominent fashion magazines, Vogue and Refinery29, seeking to understand if the publications frame their coverage differently and if the framing changes after the emergence of COVID-19. To do so, this study uses a sample consisting of articles from summer months (May-August) spanning three years (2019, 2020, and 2021), as COVID-19 was first discovered in the United States in 2020. This study uses content analysis methodology to analyze a total of 206 articles. This kind of research is important, as environmental and social issues stemming …
Association Of Early Life Stressors With Deficits In Child And Adolescent Cognitive Functioning, Emily M. Deming
Association Of Early Life Stressors With Deficits In Child And Adolescent Cognitive Functioning, Emily M. Deming
Graduate Theses, Dissertations, and Problem Reports (ETD)
The purpose of this study was to determine whether the ACEs questionnaire could be a viable screener tool for identifying children in need of neuropsychological testing. This study consisted of a sample of child participants aged 8-17 years (N=53) who were divided into a no ACEs group or the ACEs group (1 or more ACEs) depending on parental responses to the ACEs questionnaire. Participants completed a series of virtual neuropsychological tests that assessed overall neurocognitive functioning, memory, and attention. No significant differences between the no ACEs group and the ACEs group in performance of the overall Neurocognitive Index, …
Adherence To Dietary Recommendations For Adolescents With Cystic Fibrosis, Kristine M. Durkin
Adherence To Dietary Recommendations For Adolescents With Cystic Fibrosis, Kristine M. Durkin
Graduate Theses, Dissertations, and Problem Reports (ETD)
Background: Adhering to dietary recommendations and nutritional supplements to ensure adequate absorption of nutrients and malnutrition plays an important role in the health of patients with cystic fibrosis (CF). Non-adherence to the CF care regimen, including nutritional recommendations, is high in adolescents. Therefore, the overall goal of this study was to identify factors related to adherence to nutritional recommendations in adolescents with CF.
Method: A total of 42 adolescents (ages 12-18) were recruited from 5 CF centers across the US. Adolescents completed surveys measuring body image/satisfaction, health literacy, perceived barriers to enzyme use, and self-efficacy, as well as the quality …
Effects Of Depression And Stress On Oral Self-Care Among Perinatal Women In Appalachia: A Longitudinal Study, Jeongwi An
Effects Of Depression And Stress On Oral Self-Care Among Perinatal Women In Appalachia: A Longitudinal Study, Jeongwi An
Graduate Theses, Dissertations, and Problem Reports (ETD)
Oral health during the perinatal period has an impact on the health of women and their offspring. Oral self-care behaviors are preventive methods that can be employed to maintain or improve oral health but may be compromised during the perinatal period. Identifying factors affecting oral self-care behaviors might provide direction on how to intervene in oral health during and after pregnancy. The purpose of this study was to investigate independent and interactive effects of depression and stress on oral self-care behaviors of perinatal women in Appalachia, given the burden of oral disease in this region. A total of 1,172 women …
Feed Conditioning Effects On Enzymes, Amino Acids, And Subsequent Broiler Performance, Elizabeth Ann Lynch
Feed Conditioning Effects On Enzymes, Amino Acids, And Subsequent Broiler Performance, Elizabeth Ann Lynch
Graduate Theses, Dissertations, and Problem Reports (ETD)
There are many things that can be done to improve broiler performance including, but not limited to, pelleting, proper Lys inclusion, and exogenous enzyme supplementation. Pelleting has the ability to improve feed form, reduce wastage, improve bird performance metrics, and decrease pathogens within the feed. Pathogen reduction can be further reduced by hygienic pelleting practices which include an increase in temperature or retention time within a conditioner or hygieniser. However, hygienic pelleting can degrade valuable AA and enzymes (more specifically for the current thesis research Lys and phytase) and make them unavailable to the animal. Supplementing Lys to account for …
Carbon Emissions, Abatement, And Natural Disasters: Politics And Social Institutions, Ritika Khurana
Carbon Emissions, Abatement, And Natural Disasters: Politics And Social Institutions, Ritika Khurana
Graduate Theses, Dissertations, and Problem Reports (ETD)
This dissertation empirically examines three issues related to renewable energy and international development: 1) The Political Economy of Solar Initiatives in the Sunshine State; 2) Climate Change, Natural disasters, and Institutional Integrity; and 3) Institutional Integrity and Carbon emissions.
In Chapter 2, I empirically examine the outcomes of two solar energy amendments that were on the ballot in Florida in 2016. One amendment exempts solar energy devices from ad valorem taxation of real estate property, effectively decreasing the cost of solar energy for those who adopt solar photovoltaic panels. The other amendment reaffirms the right of property owners to install …
Exploring Cyberterrorism, Topic Models And Social Networks Of Jihadists Dark Web Forums: A Computational Social Science Approach, Vivian Fiona Guetler
Exploring Cyberterrorism, Topic Models And Social Networks Of Jihadists Dark Web Forums: A Computational Social Science Approach, Vivian Fiona Guetler
Graduate Theses, Dissertations, and Problem Reports (ETD)
This three-article dissertation focuses on cyber-related topics on terrorist groups, specifically Jihadists’ use of technology, the application of natural language processing, and social networks in analyzing text data derived from terrorists' Dark Web forums. The first article explores cybercrime and cyberterrorism. As technology progresses, it facilitates new forms of behavior, including tech-related crimes known as cybercrime and cyberterrorism. In this article, I provide an analysis of the problems of cybercrime and cyberterrorism within the field of criminology by reviewing existing literature focusing on (a) the issues in defining terrorism, cybercrime, and cyberterrorism, (b) ways that cybercriminals commit a crime in …
The Effects Of Feed Additives And The Use Of A Novel Wood Boiler Heat Exchanger On Litter Quality, Broiler Performance, And Immune Status, Victoria Ayres
The Effects Of Feed Additives And The Use Of A Novel Wood Boiler Heat Exchanger On Litter Quality, Broiler Performance, And Immune Status, Victoria Ayres
Graduate Theses, Dissertations, and Problem Reports (ETD)
Experiments were conducted to investigate the effects of varying feed ingredients and heating systems on boiler performance metrics. Chapter Two investigated the effects of two corn-expressed phytases, differing in enzyme concentration within the grain (3,000 or 9,677 FTU/g), on broiler performance and tibia mineralization, when used as a component in pelleted feed. Dietary treatments included a positive control (PC), with industry-recommended levels of calcium and phosphorous, and a negative control (NC), lower in calcium and non-phytate phosphorous. Six diets containing corn-expressed phytase at high or low grain concentrations, formulated to 3,000, 6,000, or 9,000 FTU/kg, were …
The U.S. Coal Industry: Market Structure & Implications, Sara Elizabeth Guffey
The U.S. Coal Industry: Market Structure & Implications, Sara Elizabeth Guffey
Graduate Theses, Dissertations, and Problem Reports (ETD)
The U.S. coal mining industry was once a booming industry which created and defined communities, particularly in Appalachia. The industry has, however, transformed significantly in the last couple of decades with the passage of environmental policies, with competition from the Shale Revolution, from changes in company ownership, and from mine safety regulation. Overall, the coal industry during this time has experienced a massive decline in production and employment. This dissertation is composed of three papers that investigate these mechanisms and their role in understanding market structure, coal transactions and prices, and mine safety outcomes. Motivated by the shutdowns of U.S. …
“The Illusion Of Collaboration”: An Integrated Examination Of The Antecedents, Processes, And Consequences Of Online Group Work, Jill Cathleen Woods
“The Illusion Of Collaboration”: An Integrated Examination Of The Antecedents, Processes, And Consequences Of Online Group Work, Jill Cathleen Woods
Graduate Theses, Dissertations, and Problem Reports (ETD)
Computer-supported collaborative learning (CSCL) presents postsecondary educators with a conundrum: how to design and support small-group activities without stifling deep and meaningful learning. The literature indicates that students are not consistently practicing higher-order cognitive activities, educators are not reliably designing or facilitating them, and/or researchers are not locating or identifying them where they are occurring. The aim of this dissertation is to explore these deficits by identifying the antecedent conditions that most affect collaboration. Specifically, I answer the question, how do learner’s prior knowledge, characteristics, and experiences manifest in their collaborative processes. Addressing a gap in the literature, this study …
Characterization Of Two Krab-Containing Zinc Finger Transcription Factors In Bovine Preimplantation Embryonic Development, Mingxiang Zhang
Characterization Of Two Krab-Containing Zinc Finger Transcription Factors In Bovine Preimplantation Embryonic Development, Mingxiang Zhang
Graduate Theses, Dissertations, and Problem Reports (ETD)
Oocyte developmental competence or oocyte intrinsic quality describes the capability of oocytes to resume meiosis, cleave and develop to blastocyst stage after fertilization, implant and develop to term in a good health. A growing number of evidences indicate that the majority of embryonic mortality occurs during early embryonic development in different species, including human, horse and cattle primarily due to poor oocyte quality. Maternal effect genes are key aspects of oocyte quality, which are transcribed during the process of oogenesis and folliculogenesis. The maternal factors are accumulated in oocytes, orchestrating various early developmental events including fertilization, epigenetic reprogramming and zygotic …
Narrative Inquiry Of Early Career Teachers’ Experiences Teaching During The Covid-19 Pandemic, Kinsey Ann Wright
Narrative Inquiry Of Early Career Teachers’ Experiences Teaching During The Covid-19 Pandemic, Kinsey Ann Wright
Graduate Theses, Dissertations, and Problem Reports (ETD)
This study utilized narrative inquiry to learn the stories of early career teachers of students with disabilities as they navigated teaching during a global pandemic. Five early career teachers participated in a series of three semi-structured virtual interviews. Interviews were transcribed then analyzed using a six-phase approach to thematic analysis (Braun & Clarke, 2006). Nine themes were identified: Teaching, Communication, Parents, Special Education, Workload, Resources, Training and professional development, job satisfaction, and teacher preparation. Themes were organized and presented to answer the research questions of the study. The findings contribute to understanding pandemic-related challenges faced by early career teachers of …
Similitude, Scaling, And Prediction Of Stream Dissolved Oxygen Across The Contiguous U.S., Aron Gebreslase
Similitude, Scaling, And Prediction Of Stream Dissolved Oxygen Across The Contiguous U.S., Aron Gebreslase
Graduate Theses, Dissertations, and Problem Reports (ETD)
Dissolved oxygen (DO) is a general indicator of stream water quality and ecosystem health. However, the concentration of in-stream DO is controlled by various climatic, land use/cover, hydrologic, biochemical, and ecological drivers. Observational data for stream DO are often unavailable at the desired temporal and spatial scales. Accurate and reliable prediction of stream DO concentration based on a small set of environmental drivers is important to guide the water managers and policymakers to achieve and maintain healthy streams. This dissertation focused on identifying the dominant controls of stream DO and understanding the mechanisms and environmental regimes by employing machine learning, …
Experience Of Parents Caring For A Child With An Acquired Disability, Brad E. Phillips
Experience Of Parents Caring For A Child With An Acquired Disability, Brad E. Phillips
Graduate Theses, Dissertations, and Problem Reports (ETD)
Background: Parents caring for a child with an acquired disability often report a negative impact on physical, psychological, emotional, and spiritual health associated with caregiver burden related to their child’s complex health needs. This is further complicated by additional challenges related to the loss of a previously healthy child. Traditional patterns of loss follow linear, time-bound stages that have been observed to be unrelated to the experiences of these specific parents and their families. Therefore, the concept transforming loss has been developed to better understand how these parents navigate loss and find meaning in spite of their suffering.
Purpose: The …
The Heart Of Everything In The Middle Of Nowhere: The Role Of Rural Identity In The Formation And Deployment Of Political Attitudes In Pennsylvania, Mikaela G. Zimmerman
The Heart Of Everything In The Middle Of Nowhere: The Role Of Rural Identity In The Formation And Deployment Of Political Attitudes In Pennsylvania, Mikaela G. Zimmerman
Graduate Theses, Dissertations, and Problem Reports (ETD)
The world of American politics continues to infiltrate households across the United States as technological advancement extends the reach of breaking news and government action. With this expanding reach, communities all over the country are digesting and contemplating their place in national politics more fervently than ever. At the crux of this discussion is the backbone of political engagement and action—identity and its resulting political attitudes. For decades, partisanship has been a point of contention amongst American citizens. Cities across the nation showcase protests, demonstrations, town hall meetings, and more illustrating citizens’ care for their democratized input in government affairs. …
Medicaid In The Orthodontic Community: Provider Trends And Perceptions, Miranda L. Fabrega
Medicaid In The Orthodontic Community: Provider Trends And Perceptions, Miranda L. Fabrega
Graduate Theses, Dissertations, and Problem Reports (ETD)
Background and Objectives: Medicaid is a federal and state insurance program aimed at helping economically disadvantaged individuals and families with gaining access to health care. Lack of provider participation in the Medicaid program leaves many Medicaid-eligible individuals with the inability to obtain certain medical services, such as orthodontic care. The objective of this study was to use an electronic survey to better understand the beliefs and behaviors of orthodontists in regard to participation in the Medicaid program, and to determine if differences exist between Medicaid providers and non-Medicaid providers. Experimental Design and Methods: Survey: Requests to participate in an electronic …
Cbct Use In Orthodontic Residency Programs In Usa, Su Min Han
Cbct Use In Orthodontic Residency Programs In Usa, Su Min Han
Graduate Theses, Dissertations, and Problem Reports (ETD)
Background and Objectives: Cone beam computed tomography (CBCT) scans in dentistry have been up and coming forms of x-ray technology that allows cross-sectional images to form a comprehensive 3-dimensional representation of the mouth. While the typical use for CBCT imaging is reported to be for implant dentistry, there are many contexts in which it is indicated in orthodontics. There are various schools of thought regarding when CBCT is indicated for specific diagnosis of problems or general use in the collection of initial, progress and post-treatment orthodontic records. There are programs that follow the Radiology guidelines for taking CBCT scans10 and …
Critical Perspectives On Produce Prescription Programs & Us Federal Nutrition Policy, Alanna K. Higgins
Critical Perspectives On Produce Prescription Programs & Us Federal Nutrition Policy, Alanna K. Higgins
Graduate Theses, Dissertations, and Problem Reports (ETD)
Produce prescription programs, interventions operating at the intersection of food access and public health, are steadily increasing in number across the United States since 2010. I leverage key informant interviews, participant observations, and event ethnographies to form a four-year institutional ethnography of the implementation of produce prescriptions within West Virginia alongside a legal-policy archaeology methodology to understand how produce prescriptions have been institutionalized and funded within the US Farm Bill. While much of produce prescription program growth is attributed to an expansion of federal funding starting in 2014, this dissertation demonstrates that these programs and the federal legislation which has …
Novel Modes Of Synchronization And Extreme Events In Coupled Chemical Oscillators, David Allen Mersing
Novel Modes Of Synchronization And Extreme Events In Coupled Chemical Oscillators, David Allen Mersing
Graduate Theses, Dissertations, and Problem Reports (ETD)
We experimentally and computationally investigate dynamical behaviors in coupled chemical oscillators. These networks of chemical oscillators are created using catalytic Ru(bpy)32+ loaded cation exchange beads submerged in catalyst-free Belousov-Zhabotinsky (BZ) solutions. Various network structures are created by utilizing the photosensitive nature of the Ru(bpy) 32+ catalyst. The response of the oscillators due to light stimuli can be characterized by constructing a phase response curve (PRC). The PRC quantifies the excitatory and inhibitory responses of BZ oscillators due to applied light perturbations as a function of the oscillators' phase. Different initial concentrations of reactants in the BZ reaction …
A Shock To The System: Analyzing Ethnocentric Populist Support Before And After Crises, Kyu Chul Shin
A Shock To The System: Analyzing Ethnocentric Populist Support Before And After Crises, Kyu Chul Shin
Graduate Theses, Dissertations, and Problem Reports (ETD)
Using the question of what is driving the support for populists in the mid-late 2010s in Western Europe and the United States as the starting point, this dissertation attempts to answer a number of different questions related to populists: Were the reasons behind support for populists in countries that saw an increase in support for populisms similar to those that saw a decrease in support? Are the reasons for supporting right-wing populists different from more general ethnocentric populists? Are the reasons that Americans supported Donald Trump similar or different from the reasons behind support for Western European populists? Following migration-related …
The Lived Experiences Of Selected Choral Directors During The Covid-19 Pandemic, Angela Berna Milliren
The Lived Experiences Of Selected Choral Directors During The Covid-19 Pandemic, Angela Berna Milliren
Graduate Theses, Dissertations, and Problem Reports (ETD)
The shift to online education during the COVID-19 pandemic found secondary choral teachers moving traditional performance-based courses to the online venue. The pedagogical changes needed include implementing technology and disseminating information through learning management systems. Relationships between teachers and students, and teachers and colleagues, were challenged with the physical distance of quarantines in the Spring of 2020. This dissertation research project examined the difficulties six teachers faced concerning technology and relationships. I sat down for semi-structured interviews with six colleagues where I asked about their backgrounds, relationships with students and fellow colleagues, and the changes the pandemic brought to their …
Appalachian Adolescents In An Out-Of-School-Time Program: Examining The Role Of Social Support From Family And Friends For Coping Skills And Intellectual Risk-Taking Outcomes, Summer Kuhn
Graduate Theses, Dissertations, and Problem Reports (ETD)
Research on young adults has emphasized the importance of social support for generating positive physical, mental, and academic outcomes. This study aims to understand the impact of social support from family and friends on coping skills and intellectual risk-taking among high school seniors participating in an Out-of-School-Time (OST) program in Appalachia. Data from the program’s annual evaluation (2014-2018) was analyzed to measure associations between perceived social support from family and friends and students’ coping skills and intellectual risk-taking. Moreover, potential differences in these associations across genders were considered. Analyses found a significant association between family-based social support and coping skills, …
Sleep And Cardiovascular Reactivity To An Acute Virtual Stressor, Alaina Grace Tiani
Sleep And Cardiovascular Reactivity To An Acute Virtual Stressor, Alaina Grace Tiani
Graduate Theses, Dissertations, and Problem Reports (ETD)
Inappropriate response and magnitude of cardiovascular reactivity (CVR) to stress is a proposed mechanism through which environmental stressors are linked with poor cardiovascular health outcomes (Chida & Steptoe, 2010; Krantz & Manuck, 1984). Studies of reactivity to various laboratory tasks commonly control for factors known to influence CVR such as smoking, medication use, caffeine intake, and BMI; however, few have considered the influence of sleep on CVR. In order to determine whether sleep characteristics need to be assessed and considered in studies of CVR, this study aimed to examine the association between indices of sleep quality and the magnitude and …
Modeling, Fabrication, And Characterization Of Rf-Based Passive Wireless Sensors Composed Of Refractory Semiconducting Ceramics For High Temperature Applications, Kavin Sivaneri Varadharajan Idhaiam
Modeling, Fabrication, And Characterization Of Rf-Based Passive Wireless Sensors Composed Of Refractory Semiconducting Ceramics For High Temperature Applications, Kavin Sivaneri Varadharajan Idhaiam
Graduate Theses, Dissertations, and Problem Reports (ETD)
Real-time health monitoring of high temperature systems (>500oC) in harsh environments is necessary to prevent catastrophic events caused by structural failures, varying pressure, and chemical reactions. Conventional solid-state temperature sensors such as resistance temperature detectors (RTDs) and thermocouples are restricted by their operating environments, sensor dimensions and often require external power sources for their operation. The current work presents the research and development of RF-based passive wireless sensing technology targeting high temperatures and harsh environmental conditions. Passive wireless devices are generally classified as near-field and far-field devices based on the interrogation distance. Near-field sensors are placed at …
Relation Of Child Feeding Behaviors & Caregiver Qualities To Adherence To Nutritional Therapy In Type 1 Diabetes Management, Corrine N. Ahrabi-Nejad
Relation Of Child Feeding Behaviors & Caregiver Qualities To Adherence To Nutritional Therapy In Type 1 Diabetes Management, Corrine N. Ahrabi-Nejad
Graduate Theses, Dissertations, and Problem Reports (ETD)
Type 1 diabetes (T1D) is a chronic illness, typically diagnosed within childhood, that affects the ability of the pancreas to produce insulin. Significant daily self-management behaviors are required to maintain metabolic control for patients with T1D. Nutritional therapy, including adequate intake of macronutrients, is one self-management behavior necessary to optimize health. Adherence to such nutritional guidelines is associated with improved glycemic control, decreased instances of acute health complications (e.g., hyperglycemia, hypoglycemia), and can also prevent insulin resistance. Despite the critical importance of nutritional therapy, adherence to these guidelines remains low within pediatric populations. Therefore, it is important and necessary to …
Playing-Related Medical Injuries And Health Conditions In Collegiate Saxophonists: A Survey Of Saxophonists In North American Universities, Michael Anne Tolan
Playing-Related Medical Injuries And Health Conditions In Collegiate Saxophonists: A Survey Of Saxophonists In North American Universities, Michael Anne Tolan
Graduate Theses, Dissertations, and Problem Reports (ETD)
When compared to other areas of musical performance, medical research on the performing arts is limited when it comes to studies on woodwind players, particularly saxophonists. The gap in research may be attributed to the circumstances surrounding selection processes and identifying subjects for study. For example, saxophonists are not salaried professionals in orchestras, which are commonly pooled for medical research. Establishing contact with saxophonists to conduct studies can prove difficult due to the wide range of genres that utilize the saxophone. Some issues may also be attributed to research methodology. To find the onset of injuries, researchers in previous studies …
Adverse Childhood Experiences And Alcohol Use Trajectories In College Students, Rebekah Lynn Damitz
Adverse Childhood Experiences And Alcohol Use Trajectories In College Students, Rebekah Lynn Damitz
Graduate Theses, Dissertations, and Problem Reports (ETD)
Heavy alcohol use during college can result in numerous negative outcomes (e.g., accidents, worse academics, risky sexual behaviors, etc.). Understanding the risk-factors associated with elevated alcohol use in college are needed so prevention and/or interventions can be implemented to inhibit such dangerous behavior. Adverse childhood experiences have been identified as one key factor in the initiation and escalation of alcohol use, but there is limited research on samples that are in emerging adulthood. Specifically, the transition to college is a time when many students escalate drinking and can form the basis for longer term drinking patterns. It is not yet …
Three Essays In Public Economics, Joylynn Michelle Pruitt
Three Essays In Public Economics, Joylynn Michelle Pruitt
Graduate Theses, Dissertations, and Problem Reports (ETD)
This dissertation presents three chapters related to each other in their application to public economics. In the study of how utility-maximizing or goal-seeking units achieve economic outcomes, this dissertation presents results for a diverse range of agents including prosecutors and liberal arts colleges. Co-authored with Dr. Bryan McCannon of West Virginia University, the first chapter examines an interesting feature of prosecutor elections, where the pool of potential challengers to an incumbent comes primarily from subordinates within the office. We develop a signaling model that analyzes whether entry into the political race by a subordinate provides voters with useful information. In …
Bone Marrow Stroma-Induced Transcriptome Signatures Of Multiple Myeloma As Modulated By Junb, Jasleen Kaur Gandhi
Bone Marrow Stroma-Induced Transcriptome Signatures Of Multiple Myeloma As Modulated By Junb, Jasleen Kaur Gandhi
Graduate Theses, Dissertations, and Problem Reports (ETD)
The bone marrow (BM) microenvironment acts as a breeding ground for drug resistance in multiple myeloma (MM). The interaction with bone marrow stromal cells (BMSCs) confer environment-mediated drug resistance (EMDR) to multiple myeloma. We investigated BM stroma-induced transcriptome signatures of MM cells through a sophisticated analysis of gene expression. In particular, we defined transcription program modulated by JunB, an emerging regulator of MM pathogenesis and a member of the transcription factor superfamily activator protein 1 (AP-1), in response to BM stimulation. The data and results lay down a foundation for future studies to illustrate the regulatory role of JunB in …