Resource Affluence And Sustainable Consumer Behavior, Liguo Liu

Graduate Theses, Dissertations, and Problem Reports (ETD)

While resource affluence is desired by most individuals, it may not always be advantageous for a collective group. Recent research documents some “dark side” effects associated with resource affluence, such as reducing people’s willingness to help others or leading to unethical behaviors (e.g., Piff et al. 2012; Vohs et al. 2016). Building on this body of work and advances in sustainability research, this study investigates the impact of financial affluence on sustainable consumer behavior. Using a multi-method approach (archival data and experiments), this study demonstrates that financial affluence leads to less sustainable consumer behaviors compared to a control group, across …

Contracture Management For Acute Burn Injury Patients, Brianna Paige Pestrosky

Graduate Theses, Dissertations, and Problem Reports (ETD)

Background: The Occupational Therapists working within the burn unit at West Penn Hospital assess and treat patients utilizing the biomechanical approach FOR, as well as the support from MOHO and PEOP. The patients seen within the burn unit encompass a variety of injuries and occupational deficits that require an individualized and holistic approach to care.

Purpose: The purpose of the contracture management project is to provide an interdisciplinary approach to improve carryover and patient care within and out of the hospital.

Theoretical framework: The contracture management project is guided using the biomechanical frame of reference as well as supporting constructs …

Comparison Between Coronally Advanced Flap With Sub-Epithelial Connective Tissue Graft And Tunnel Technique With Sub-Epithelial Connective Tissue Graft In Achieving Mean Root Coverage At Multiple Recession Defects: A Retrospective Study, Christian Daniel Davila

Graduate Theses, Dissertations, and Problem Reports (ETD)

Aim: The primary objective is to retrospectively compare the mean root coverage (MRC) achieved using a coronally advanced flap and sub-epithelial connective tissue graft (CAF + CTG) with that achieved using the tunnelling technique and sub-epithelial connective tissue graft (TUN + CTG) for the treatment of multiple recession defects. The secondary objectives are to compare the proportion of complete root coverage (CRC) achieved with CAF + CTG compared to TUN + CTG, compare the proportion of CRC achieved in these two techniques with respect to level of training (American board-certified periodontist or Graduate periodontics residents) and to evaluate the …

Puberty-Associated Changes In Kiss1r, Mc3r, And Mc4r In The Ewe, Ashleigh Caitlyn Thomson

Graduate Theses, Dissertations, and Problem Reports (ETD)

The neural mechanisms that control the onset of puberty are not completely understood. In livestock, the onset of puberty relies on an increase in gonadotropin releasing hormone (GnRH) and luteinizing hormone (LH). Kisspeptin, neurokinin B, and dynorphin neurons (KNDy) and their receptors, Kiss1r, NK3R, and KOR, respectively, are important regulators of puberty. Previous data from our laboratory has shown that KNDy neurons may be responding to other inputs, including the melanocortin system, that will affect the timing of puberty. Given this, we examined kisspeptin receptor (Kiss1r) mRNA expression in GnRH neurons as well as examining melanocortin 3 and 4 receptor …

A Randomized Need-Supportive Intervention With U.S. Youth Hockey Coaches, Diane Benish

Graduate Theses, Dissertations, and Problem Reports (ETD)

Coach behaviors impact several essential athlete factors such as the quality of athlete motivation and psychological functioning and yet, many youth coaches remain untrained in motivation and athlete-centered principles. This study’s aim was to explore the efficacy of a need-supportive intervention on youth hockey coaches’ attitudes toward, and reported use of, need-supportive and/or need-thwarting approaches. Participants included 25 youth hockey coaches randomly assigned to an intervention or delayed control condition. Grounded in Self-Determination Theory, the intervention included four sessions within which coaches learned how to adopt need-supportive coaching strategies and reduce need-thwarting tactics. A mixed-methods approach guided the evaluation of …

Examining Invalid Brief Child Abuse Potential Inventory Profiles Within A Randomized Controlled Trial For Toddler-Aged Children And Their Parents, Lindsay Rebecca Druskin

Graduate Theses, Dissertations, and Problem Reports (ETD)

Child abuse is a significant public health concern that impacts children worldwide. Efforts to connect at-risk parents with prevention and intervention programs require the use of high-quality measures that evaluate child abuse potential. Researchers frequently use the Child Abuse Potential Inventory (Milner, 1986) and the Brief Child Abuse Potential Inventory (BCAP; Ondersma et al., 2005) which contain Validity indices that evaluate response patterns such as social desirability responding. The measure developers recommended that abuse risk scores from invalid profiles be disregarded in clinical and research settings; however, little is known about factors that may relate to invalid responses and whether …

Characterization Of Host Cell Specific Interactions During Spotted Fever Group Rickettsiae Infection, Emerson Towey

Graduate Theses, Dissertations, and Problem Reports (ETD)

Vector-borne diseases have been increasing over the past few years due to changes in climate and disturbances in the vectors’ natural environment. To mitigate the risks of these diseases, it is necessary to understand pathogen biology and how it interacts with a host to cause disease. Here we focus our attention on the tick-borne pathogen, Rickettsia rickettsii. R. rickettsii is a member of the spotted fever group (SFG) Rickettsiae and is the etiological agent of Rocky Mountain spotted fever (RMSF), a fatal human disease that is lacking an effective vaccine. Members of the bacterial genus Rickettsia are obligate intracellular endoparasites …

Impact Of Tiered Implementation Of Clinical Decision Support System For Acute Kidney Injury And Nephrotoxin Exposure In Cardiac Surgery Patients, Christopher M. Justice Ii

Graduate Theses, Dissertations, and Problem Reports (ETD)

Background: Nephrotoxin exposure may worsen kidney injury and impair kidney recovery if continued in patients with acute kidney injury (AKI).

Objective: To determine if tiered implementation of a clinical decision support system (CDSS) would reduce nephrotoxin use in cardiac surgery patients with AKI.

Methods: We assessed patients admitted to the cardiac surgery intensive care unit at a tertiary care center from January 2020 to December 2021, and August 2022 to September 2023. A passive electronic AKI alert was activated in Jul 2020, followed by an electronic nephrotoxin alert in March 2023. In this alert, active nephrotoxic medication orders resulted in …

Increasing First-Attempt Endotracheal Intubation Success Rates In The Aeromedical Environment, Jared Copeland

Graduate Theses, Dissertations, and Problem Reports (ETD)

Problem Statement: In 2022, the first-attempt endotracheal intubation success rate of an aeromedical agency had steadily declined and was currently below the international average of 88.48%. This decreased success rate potentially placed patients at risk for adverse events that increase morbidity and mortality. Background: Patients who experience a failed first-attempt intubation are at greater risk of intubation related complications. These complications include hypoxemia episodes, severe arrhythmias, pulmonary aspiration, hypotension episodes, cardiac arrest, and death. Literature Review: Preoxygenation, patient positioning, maintenance of oxygenation, drug selection, and device utilization have been found to increase first-attempt endotracheal success rates. Project Aims: The project …

Evaluating The Impact Of Ergonomic Interventions On Reducing Knee Musculoskeletal Disorder Risks During Residential Roof Shingle Installation: A Phase-Level Analysis, Nazia Zerin

Graduate Theses, Dissertations, and Problem Reports (ETD)

The prevalence of knee musculoskeletal disorders (MSDs) among roofers due to awkward kneeling postures during shingle installation is a well-recognized concern. While knee-saving interventions like knee savers (KSs) and knee pads (KPs) have shown the potential to reduce MSD risks, their effectiveness across different phases of shingle installation remains unknown. The objective of this study is to assess how interventions of KSs and KPs alleviate the risks of MSDs in the knees during various phases of shingle installation. These phases include (1) reaching for shingles, (2) placing shingles, (3) grabbing a nail gun, (4) moving to the first nailing position, …

Implementation Of Provider In Triage Guidelines To Improve Emergency Department Throughput: A Quality Improvement Project, Benjamin Adam Klos

Graduate Theses, Dissertations, and Problem Reports (ETD)

Introduction/Background

Emergency department overcrowding is a national problem that causes adverse effects on patients, providers, and healthcare systems. Locally, wait times can be up to six hours. Emergency department census increases yearly without an increase in physical space.

Purpose

The project aimed to improve throughput and provide quality care to patients in an emergency department waiting room.

Intervention

A provider in triage guideline was written to improve emergency department throughout metrics and guide care.

Methods

Pre- and post-implementation statistics were compared. The Logic model was used to guide project implementation.

Results

Door to provider and arrival to discharge times decreased …

Comparative Analysis Of Chemical Compounds And Metal Contaminants In Medical Grade Versus Over-The-Counter Sodium Hypochlorite Solutions, Abdulrahman Essaedi

Graduate Theses, Dissertations, and Problem Reports (ETD)

Introduction:

Abstract

Endodontic treatment aims to prevent or address apical periodontitis by reducing intracanal bacterial populations to promote tissue healing, requiring thorough debridement and disinfection of the canal space. This study aims to examine the presence of trace metal elements and chemical compounds in over-the-counter (OTC) and medical-grade sodium hypochlorite (NaOCl) solutions.

Method

Over-the-counter NaOCl brands (Clorox® and Great Value®) and medical grade 6% NaOCl solutions (CanalPro® and Chlor-Xtra®) were purchased, stored in amber glass bottles, and tested in triplicate. Each was analyzed using mass spectrometry, identifying 7881 chemical compounds with statistical comparisons via adjusted p-values, fold-change, and heat maps. …

Dentin-Sealer Bond Strength. A Review: An In-Vitro Comparison Between Guttaflow 2 ®, Endosequence Bc High Flow ®, Tubli-Seal ®, Sealapex ®, And Ah Plus Jet ® Sealers., Zied Diab

Graduate Theses, Dissertations, and Problem Reports (ETD)

Introduction: One objective of non-surgical endodontic therapy is the formation of a hermetic seal with elimination of any portal of entry of bacteria and their byproducts into the root canal space from periapical tissue. Extensive research has been conducted to determine ideal endodontic sealers. Bioceramic sealers have risen to prominence due to reported decreased shrinkage, less toxicity, and superior bond strength to root dentin compared to zinc oxide eugenol, calcium hydroxide, and resin-based sealers. GuttaFlow2®, a new sealer on the market, is composed of calcium silicate in combination with gutta-percha particles. Researchers from Coltene (Altstätten, Switzerland), the manufacturer of GuttaFlow2® …

Investigating Changing Macronutrient Dynamics At A Plant, Microbe And Plant-Microbe Interactions Scale, Emel Kangi

Graduate Theses, Dissertations, and Problem Reports (ETD)

Nutrient limitation drives forest ecosystem processes by altering net primary production, belowground (C) investments, and microbial activity. As such, the availability of essential macronutrients, such as nitrogen (N) and phosphorus (P), can severely impact plant growth, microbial decomposition, and the strength of plant-microbial interactions. However, our understanding of plant and microbe responses to changing nutrient availability, and the extent to which nutrient availability affects plant-microbe interactions, remains somewhat limited. Therefore, in this dissertation, I aimed to investigate nutrient limitation on a plant, microbe, and plant-microbe interaction level. First, to connect the phenotypic responses of nutrient-limited plants to key molecular mechanisms, …

Feminist Pedagogy In The Esl Classroom: A Retrospective Qualitative Case Study, Lindsei Pereira Da Silva

Graduate Theses, Dissertations, and Problem Reports (ETD)

Even though feminist pedagogy in the context of higher education has been widely researched, there is a dearth of scholarship available when it comes to feminist pedagogy in the context of English as a Second Language. The present retrospective qualitative case study investigated the ways in which feminist pedagogy is represented in the teaching philosophies and intended teaching practices of ESL instructors in the Summer 2023 Fulbright Pre-Academic Program. The research findings indicate that feminist pedagogy was represented in the teaching philosophies and intended teaching practices of the ESL instructors in several ways, despite the fact that they had not …

Improving Patient Self-Advocacy And Communication With Providers Through Diabetes Self-Management Education: Analyses From A Randomized Controlled Trial, Brenna Owens Kirk

Graduate Theses, Dissertations, and Problem Reports (ETD)

Background: West Virginia (WV), a rural state in Appalachia, has the highest type 2 diabetes mellitus (T2DM) prevalence in the United States. Open communication in the patient-provider relationship is an integral part of comprehensive chronic disease management. This is especially true for patients living with T2DM, a disease that requires many complex, daily self-management activities and is associated with increased emotional distress. However, patients living with T2DM are often reluctant to openly share their concerns regarding self-care with their provider. This study aimed to test the effectiveness of the Diabetes and Hypertension Self-Management Program (DHSMP), a 12-week group lifestyle …

Risk Of Parasiticides To Dung-Associated Beetles In West Virginia, Haylie J. Brown

Graduate Theses, Dissertations, and Problem Reports (ETD)

Ecosystem services provided by dung-associated beetles, such as reducing pasture fouling, parasite suppression, supporting nutrient recycling, and increasing water infiltration, contribute to animal and pasture health. However, parasiticides used to manage cattle parasites, particularly flies and helminths, in West Virginia, can adversely affect these non-target beetles. We assessed the exposure and impact of some parasiticides used in WV including Clarifly^® (active ingredient [a.i.] diflubenzuron), Cydectin^® (a.i. moxidectin), LongRange^® (a.i. eprinomectin), and Safe-guard^® (a.i. fenbendazole). In Chapter 1, we review the use of parasiticides in the US and their non-target effects on beneficial dung-associated beetles. In Chapter …

Development Of Probabilistic Dynamic Model Building And Bayesian Machine Learning Approaches, Samuel Oladayo Adeyemo

Graduate Theses, Dissertations, and Problem Reports (ETD)

Abstract

Development of Probabilistic Dynamic Model Building and Bayesian Machine Learning Approaches

Samuel Adeyemo

The recent years have seen a tremendous increase in the use of artificial intelligence (AI) and machine learning (ML) for the development of data-driven mathematical models needed for performing real-time optimization, model-based control, performance optimization, dynamic data reconciliation, and process performance monitoring. However, the development of data-driven models is faced with some challenges including lack of model interpretability, sensitivity of algorithm to noise in training data, limited extrapolation capabilities and violation of conservation laws. Drawing motivation from these existing gaps, this work aims to develop robust …

Implementing A Nurse-Driven Clostridium Difficile Screening Protocol, Sandrela Magnuson

Graduate Theses, Dissertations, and Problem Reports (ETD)

ABSTRACT

Background: Clostridium difficile infection (CDI) is a prevalent infection often contracted in hospitals. CDI is also increasingly originating from community settings. In addition to the health risks associated with CDI, diagnosis of a hospital-acquired CDI can have a significant financial impact on hospital systems. When hospital acquired, hospital systems are no longer reimbursed by payers. Secondary to the increasing prevalence of community-acquired CDI, mechanisms for early detection and isolation are warranted.

Local Problem: J.W. Ruby Memorial Hospital has an integrated Clostridium difficile (C. difficile) electronic health record (EHR) screening questionnaire that requires updating to align with current guidelines.

Purpose: …

Role Of Β4b-Tubulin (Tubb4b) In The Sensory System And Spermatogenesis, Urikhan Sanzhaeva

Graduate Theses, Dissertations, and Problem Reports (ETD)

Microtubules are ubiquitous cytoskeletal filaments essential in the function of eukaryotic cells. These polymers, comprised of αβ-tubulin heterodimers, are critical for cell division, intracellular transport, and formation of the axonemes of cilia and flagella. This functional diversity of microtubules is attributed to the incorporation of various α- and β-tubulin isotypes encoded by different genes. Indeed, mutations in human tubulin genes have been linked to various tissue-specific diseases, suggesting a unique function for each tubulin isotype. Mutations in the β4B-tubulin gene (TUBB4B) are associated with sensorineural hearing loss, Leber Congenital Amaurosis (LCA), a severe childhood blindness, and primary ciliary dyskinesia …

Advanced Techniques In Time Series Forecasting: From Deterministic Models To Deep Learning, Xue Bai

Graduate Theses, Dissertations, and Problem Reports (ETD)

This dissertation discusses three instances of temporal prediction, applied to population dynamics and deep learning.

In population modeling, dynamic processes are frequently represented by systems of differential equations, allowing for the analysis of various phenomena. The first application explores modeling cloned hematopoiesis in chronic myeloid leukemia (CML) via a nonlinear system of differential equations. By tracking the evolution of different cell compartments, including cycling and quiescent stem cells, progenitor cells, differentiated cells, and terminally differentiated cells, the model captures the transition from normal hematopoiesis to the chronic and accelerated-acute phases of CML. Three distinct non-zero steady states are identified, representing …

The Effects Of Diet-Induced Obesity On Cerebral Microvascular Bioenergetics, Alec Anthony Hanshew

Graduate Theses, Dissertations, and Problem Reports (ETD)

Obesity is a worldwide epidemic but is especially a concern in the United States with over 40% of the population being obese. Obesity is known to cause increased metabolic demand, systemic inflammation, peripheral vascular dysfunction, and increased levels of oxidative stress and reactive oxygen species (ROS). However, the role of obesity on cerebrovascular bioenergetic function has not been fully elucidated. This study aimed to determine the impact of diet-induced obesity on cerebrovascular bioenergetics. 72, 6-month-old C57Bl/6 male and female mice were randomized into control and HFD groups. Control mice were subjected to the feeding of standard chow (18% fat, 24% …

Translational Approaches To Address The Metastatic/Resistant (Mr) Phenotype Of Non-Small Cell Lung Cancer Brain Metastases, Kent L. Marshall

Graduate Theses, Dissertations, and Problem Reports (ETD)

Lung cancer remains the most frequently diagnosed malignant neoplasm shared in men and women worldwide, second only to the sexually dimorphic prostate cancer in men and breast cancer in women. Overall, lung cancer was responsible for 12.5% of new cancer cases globally in the year 2022. Of these cases, 80-85% are non-small cell lung cancer (NSCLC), a highly genotypically diverse sub-type of lung cancer. Over the past three decades, extraordinary improvement in screening, smoking cessation, early diagnosis and targeted therapy have been made, improving NSCLC survival markedly. However, as patients are surviving their primary disease better, there is a temporal …

Developing And Adapting An Art Therapy Mask Creation (Atmc) Intervention For Individuals With Traumatic Brain Injury (Tbi) Across Select Clinical And Non-Clinical Settings, Stephen John Heck

Graduate Theses, Dissertations, and Problem Reports (ETD)

The study aimed to explore the feasibility and adaptation of the Art Therapy Mask Creation (ATMC) technique in select clinical and non-clinical settings for individuals with traumatic brain injuries (TBIs). Utilizing the Consolidated Framework for Implementation Research (CFIR), qualitative interviews were conducted to assess barriers, facilitators, and feasibility of implementing the ATMC. Major findings included the ATMC’s adaptability across diverse settings, the flexibility and accessibility of art therapy as an intervention, and the significance of addressing emotional and psychological needs in individuals with TBIs. These insights contributed to understanding evolving healthcare practices, the role of technology, the importance of human …

The Identification And Characterization Of Novel And Improved Antigens For Next-Generation Pertussis Vaccines, Gage Michael Pyles

Graduate Theses, Dissertations, and Problem Reports (ETD)

Whooping cough, or pertussis, is a highly infectious respiratory disease caused by infection with the Gram-negative bacterial pathogen Bordetella pertussis. Pertussis affects all age groups and populations; however, it is most severe in infants who are too young to receive vaccinations and remains a global health concern with more than­­­­ 200,000 cases reported globally in 2023. Vaccines against pertussis have been available in the United States since the 1940’s with the development and widespread use of whole cell pertussis vaccines. Following their introduction, the incidence of pertussis was controlled and limited to fewer than 5,000 cases per year. Despite …

Performance And Physiological Impacts Of Branched-Chain Amino Acid And Tryptophan Ratio Variations In Turkey Starter Diets Utilizing Concentrated Corn Proteins, Emily Blair Estanich

Graduate Theses, Dissertations, and Problem Reports (ETD)

In Chapter 2, a study was designed to evaluate the effects of varying dietary branched-chain amino acids (BCAA) ratio in corn and soybean meal-based turkey starter diets. The BCAA leucine, isoleucine, and valine are considered indispensable amino acids needed for energy and stimulation of muscle protein synthesis via the mammalian target of rapamycin (mTOR) pathway. Imbalanced BCAA ratios can lead to antagonism and degradation of limiting BCAA, particularly in diets with excess leucine. Concentrated corn proteins contain high levels of leucine and can alter BCAA requirements; however, crystalline BCAA may be added to correct these ratios. This study aimed to …

Examining The Online Marketing Of Sport Psychology Services By Certified Mental Performance Consultants: A Rhetorical Analysis, Jaxson S. Judkins

Graduate Theses, Dissertations, and Problem Reports (ETD)

In recent years, Certified Mental Performance Consultants (CMPCs) have increased their footprint in social media to connect with those that seek sport psychology services (Cotterill & Symes, 2014). The aim of this study was to identify what social media platforms are most used among CMPCs and what persuasive elements are used to draw in potential clients. All active CMPCs from 1992 to 2023 were examined to determine the most popular social media platforms used, followed by an analysis of 219 CMPCs based on their ownership of a LinkedIn account and professional website. Results indicated that LinkedIn and the consultants’ custom …

Pathways To Health: Linking Accessible Green Space To Improved Health And Well‐Being In Rural Appalachia., Udday Shankur Datta

Graduate Theses, Dissertations, and Problem Reports (ETD)

Green spaces are essential for our physical health. The quality of its green space often determines the health of a community. The presence of green space in our lives is associated with reduced stress levels, better sleep, and increased feelings of safety. Lack of access to green space can lead to many health issues, such as high blood pressure, diabetes, and cardiovascular diseases, and has been linked to obesity and physical inactivity.

The Appalachian Regional Commission (ARC) defines Appalachia as a region covering 420 counties across 13 states in the eastern United States. A large part of this region is …

Cell-Type-Specific Effects Of Synaptic Zinc In Mouse Auditory Cortex, Mason Mccollum

Graduate Theses, Dissertations, and Problem Reports (ETD)

Synaptic zinc signaling modulates synaptic activity and is present in specific populations of cortical neurons, suggesting that synaptic zinc contributes to the diversity of intracortical synaptic microcircuits and their auditory tuning properties. Stimulus-specific adaptation is a hallmark of sensory processing in which a repeated stimulus results in diminished successive neuronal responses, but a deviant stimulus will still elicit robust responses from the same neurons. Recent work has established that synaptically released zinc is an endogenous mechanism that shapes neuronal responses to sounds in the auditory cortex. Here, to understand the role of zinc signaling in the auditory cortex and the …

The Effects Of Forgetting And Disclosure On Mock Jurors' Perceptions Of An Alleged Rape, Johnathan Meier

Graduate Theses, Dissertations, and Problem Reports (ETD)

Memory recall and forgetting is a complex process. Memories can be completely forgotten (e.g., Ebbinghaus, 1885/1964; Murre, 2015) or repressed and recovered at a later time (e.g., Key et al., 1996; Foster-Lee et al., 1999). Instances of sexual assault may be disclosed to a close acquaintance or medical professional at the time of the event or kept secret until the time of reporting to authorities (e.g., Pica et al., 2020a). In the current study, mock jurors’ perceptions of credibility and guilt, as well as the amount of compensation awarded to the plaintiff, will be assessed in response to testimony depicting …