Digital Commons Network^™

Metal Nanomaterials: Immune Effects And Implications Of Physicochemical Properties On Sensitization, Elicitation, And Augmentation Of Allergic Disease, Katherine Adair Roach

Graduate Theses, Dissertations, and Problem Reports (ETD)

Many allergenic metals are being manufactured in nanoparticulate forms. Although the decreased size profile of metal nanomaterials has been consistently associated with more pronounced lung toxicity compared to larger materials, it is unclear if metal-induced immunotoxic effects exhibit a similar size-dependency.

The central hypothesis of these studies was that metal nanoparticles cause more pronounced immunomodulatory effects on allergic processes than larger forms of respective metals. Moreover, it was anticipated that, similar to their inflammatory potential in airways, the magnitude of these responses would correlate best with the dose metric of surface area.

The first set of studies utilized fine and …

Discrimination And Behavioral Responses To Communication Signals Compared Across Apteronotids., Danielle Leigh Dillon-Seeger

Graduate Theses, Dissertations, and Problem Reports (ETD)

Sensory systems are often uniquely tailored to encode behaviorally relevant signals and comparative studies across species can thus reveal how evolutionary changes shape sensory functions. The structure of communication signals varies widely between ghost knifefish species. Recent findings suggest that the nervous system co-adapted to the various signal structures observed across species to support different sensory behaviors. The aim for this thesis was to compare the sensory behavior of 3 species of ghost knifefish to contrast their behavioral performance with the known differences in neurophysiology. We hypothesize that for the different signal types and species, the ability to discriminate small …

Low-Power Reconfigurable Sensing Circuitry For The Internet-Of-Things Paradigm, Alexander Dilello

Graduate Theses, Dissertations, and Problem Reports (ETD)

With ubiquitous wireless communication via Wi-Fi and nascent 5th Generation mobile communications, more devices -- both smart and traditionally "dumb" -- will be interconnected than ever before. This burgeoning trend is referred to as the Internet-of-Things. These new sensing opportunities place a larger burden on the underlying circuitry that must operate on finite battery power and/or within energy-constrained environments. New developments of low-power reconfigurable analog sensing platforms like field-programmable analog arrays (FPAAs) present an attractive sensing solution by processing data in the analog domain while staying flexible in design. This work addresses some of the contemporary challenges of low-power wireless …

Browsing Via Sonification, Taylor C. Cutlip

Graduate Theses, Dissertations, and Problem Reports (ETD)

Based on unexpected results in her previous research, Dr. Frances Van Scoy became inspired to develop a tool that allows the user to navigate spaces using auditory instead of visual cues to detect objects or anomalies in a given space in an effort to overcome the encountered obstacles. This problem report details the work of one of her grad students in exploring different open source software for developing the tool as well as research into gestures and other considerations when furthering this research into the third dimension at a future date.

Design Of Geothermal District Heating And Cooling System For The West Virginia University, Oluwasogo Bolaji Alonge

Graduate Theses, Dissertations, and Problem Reports (ETD)

Recent Appalachian Basin Geothermal Play Fairway Analysis estimated elevated heat flows in north-central West Virginia. This region provides an optimal and unique combination of elevated temperatures and flow necessary for geothermal development along with year-round surface demand for heating and cooling on the campus. Therefore, West Virginia University’s (WVU’s) Morgantown campus has been identified as a prime location in the eastern United States for the development of a geothermal direct-use heating and cooling application. The objective of this study was to perform a feasibility analysis for the development of a geothermal district heating and cooling (GDHC) system for WVU campus …

Cash For Consideration? An Examination Of Academics, Demographics, And Student Socioeconomics In The Provisioning Of Institutional Aid., Matthew G. Matyasovsky

Graduate Theses, Dissertations, and Problem Reports (ETD)

This dissertation is an empirical investigation of student level observations of 11 cohorts of first-time full-time freshmen from a public, land-grant, research university in Appalachia. Complete with student financial aid offerings, socioeconomic status, and pre-college academic characteristics such as standardized test scores and high school GPA, I investigate the data to examine institutional behavior constrained by resource dependence. The variable of interest is institutional financial aid. Institutional financial aid awards are monetary concessions presented to students as a means to discount the overall price a student pays to enroll. As institutional aid is a direct mechanism through which the institution …

Enhancing The Thermoelectric Performance Of Calcium Cobaltite Ca3co4o9 Through Single And Dual Elements Doping, Cesar Octavio Romo De La Cruz

Graduate Theses, Dissertations, and Problem Reports (ETD)

Worldwide energy consumption losses more than 60% of the energy after its conversion, most of these losses are in the form of waste heat. Therefore, it is a matter of utmost importance to harness waste heat and reutilize this energy source to improve the overall conversion efficiency. Thermoelectric (TE) technology is one of the rising alternatives to harvest the excessive amount of energy lost as waste heat for a better and sustainable energy future. TE materials can utilize waste heat to improve efficiency in the ever-increasing demand for energy by converting a temperature difference directly into electricity due to the …

Experimental And Numerical Study Of The Stirling Engine Robust Foil Regenerator, Koji Yanaga

Graduate Theses, Dissertations, and Problem Reports (ETD)

The regenerator is located between the heat accepter and the heat rejecter of the Stirling engine. It works as a thermal energy storage component in the engine. Most of the regenerators are made of woven screen or random fiber. However, the flow going through the woven screen or random fiber is similar to the cylinders in crossflow which has flow separation. To achieve higher engine efficiency, it is required to design a regenerator which has higher convective heat transfer, lower pressure drops. Therefore, a parallel channel regenerator called a robust foil regenerator was designed and manufactured.

In this study, a …

Low Power Voltage Reference Cells For Sensing Applications, Kody Ray Tucker

Graduate Theses, Dissertations, and Problem Reports (ETD)

Two low-power voltage reference cells for a system on-chip design are presented in this report. Both cells utilize a combination of standard transistors to produce an output voltage near 1 volt. Choosing the appropriate design procedures can aid in minimizing the temperature coefficient (TC) of the output reference voltage coming out of the cell. One circuit, covered first, is currently being fabricated on a standard 0.5 µm chip complementary metal oxide semiconductor (CMOS) process, while the other is still in the designing stage. The first one has a TC of 86 ppm/◦C with a reference voltage of 1.10 V while …

Hyperscales: Analysis, Historical Uses, And Possible Applications In Contemporary Music Composition, Douglas Wayne Brown

Graduate Theses, Dissertations, and Problem Reports (ETD)

This paper introduces the hyperscale, defines terminology that is new or potentially ambiguous, examines historical scales which may be a hyperscale or not (with examples when available), introduces two synthetic hyperscales created by the author, tells the story behind their creation through an analysis of an original piece by the author that uses both scales, compares the scale characteristics and composition techniques used in the piece with those of another piece written by a contemporary composer, and finally offers some concluding thoughts on the future of the hyperscale in art music. Because relatively little scholarship exists for this topic, this …

The Evaluation Of The Rapidhittm 200 On Degraded Biological Samples, Alice Kim

Graduate Theses, Dissertations, and Problem Reports (ETD)

DNA (deoxyribonucleic acid) has become an integral part of forensic science in the last couple of decades since its discovery to this application by Alec Jeffreys. Although there have been many advances throughout the years, the time it takes to obtain a DNA profile using conventional methods in a laboratory setting is approximately 24 to 72 hours. Due to this length of time and the increase in demand for DNA testing, it has caused a tremendous amount of backlog throughout the country. In 2009, the FBI (Federal Bureau of Investigation) in collaboration with the US Department of Defense of Homeland …

Artificial Immune System For Unmanned Aerial Vehicle Abnormal Condition Detection And Identification, Ryan G. Mclaughlin

Graduate Theses, Dissertations, and Problem Reports (ETD)

A detection and identification scheme for abnormal conditions was developed for an unmanned aerial vehicle (UAV) based on the artificial immune system (AIS) paradigm. This technique involves establishing a body of data to represent normal conditions referred to as “self” and differentiating these conditions from abnormal conditions, referred to as “non-self”. Data collected from simulation of the UAV attempting to autonomously fly a pre-decided trajectory were used to develop and test a scheme that was able to detect and identify aircraft sensor and actuator faults. These faults included aerodynamic control surface locks and damages and angular rate sensor biases. The …

Immunomagnetic Beads Coupled With Anti-Ph-20 Antibodies To Isolate Sperm From Dna Mixtures For Sexual Assault Kit Application, Kayla Becks

Graduate Theses, Dissertations, and Problem Reports (ETD)

Sexual Assault Kits (SAKs) account for a large portion of DNA mixture samples that are processed within a forensic laboratory, most commonly in the form of vaginal swabs. A typical vaginal swab from a SAK contains the female victim's epithelial cells and varying concentrations of sperm cells left by the perpetrator. The key to analyzing these types of samples is to separate the mixture into male and female fractions. As such, there is a demand to develop novel techniques that have the capability of recovering as much of the male fraction as possible, specifically in cases where there is a …

A Biomimetic Approach To Controlling Restorative Robotics, Matthew T. Boots

Graduate Theses, Dissertations, and Problem Reports (ETD)

Movement is the only way a person can interact with the world around them. When trauma to the neuromuscular systems disrupts the control of movement, quality of life suffers. To restore limb functionality, active robotic interventions and/or rehabilitation are required. Unfortunately, the primary obstacle in a person’s recovery is the limited robustness of the human-machine interfaces. Current systems rely on control approaches that rely on the person to learn how the system works instead of the system being more intuitive and working with the person naturally. My research goal is to design intuitive control mechanisms based on biological processes termed …

Improving Broiler Performance Utilizing Modern Feed Additives, Niles Rourke Ridgeway

Graduate Theses, Dissertations, and Problem Reports (ETD)

Modern broiler production strives to make modest improvements regarding broiler performance. This remains a goal as global population increases thusly increasing the quantity of an affordable, high quality source of protein. In recent years, an added stressor to achieving prior goals is mostly related to consciousness of environmental and consumer health. For decades, integrators have utilized minimal amounts of antibiotics as a barrier to most pathogens affecting the microbiome of a broiler’s gastrointestinal tract. Regulatory efforts have now prohibited most of previous sub-therapeutic medicine and started an in-depth scope of broiler gut health and interaction with antibiotic alternatives. In an …

Rule Extraction And Insertion To Improve The Performance Of A Dynamic Cell Structure Neural Network, Osama Amhamed Elsarrar

Graduate Theses, Dissertations, and Problem Reports (ETD)

Artificial Neural Networks are extremely useful machine learning tools. They are used for many purposes, such as prediction, classification, pattern recognition, etc. Although neural networks have been used for decades, they are still often not completely understood or trusted, especially in safety and mission critical situations. Typically, neural networks are trained on data sets that are representative of what needs to be learned. Sometimes training sets are constructed in order to train the neural network in a certain way, in order to embed appropriate knowledge. The purpose of this research is to determine if there is another method that can …

Virtual Morphology As A Method Of Robotic Control, Conner Todd Castle

Graduate Theses, Dissertations, and Problem Reports (ETD)

This thesis presents Virtual Morphology (VM), a method that explores a different perspective on the design of robot autonomy using inspiration from morphological computing and programmed computation. Morphological computation offers physical solutions that solve complex tasks, like robotic grasping of unknown objects, with relative ease. Unfortunately, these physical solutions are difficult to adjust post-development, and are usually designed to complete only one or a few specific tasks. Programmed computational approaches are more flexible because they can be implemented and adjusted through software, but unfortunately, these approaches can become rather complex as tasks become more difficult. This thesis explores the potential …

Investigation And Development Of Exhaust Flow Rate Estimation Methodologies For Heavy-Duty Vehicles, Chakradhar Reddy Vardhireddy

Graduate Theses, Dissertations, and Problem Reports (ETD)

Exhaust gas flow rate from a vehicle tailpipe has a great influence on emission mass rate calculations, as the emission fractions of individual gases in the exhaust are calculated by using the measured exhaust flow rate. The development of high-end sensor technologies and emission pollutant measurement instruments, which can give instantaneous values of volume concentration of pollutants flowing out of the engine are gaining importance because of their ease of operation. The volume concentrations measured can then be used with the instantaneous exhaust flow rate values to obtain mass flow rates of pollutants.

With the recent promulgation of real world …

The Politics Of Drug Courts, Jeffrey Chris Moss

Graduate Theses, Dissertations, and Problem Reports (ETD)

This study examined drug courts from a public policy and political science perspective. The first portion of the study focused on the history of sentencing policy from the 1970s through the drug court movement. The second chapter addressed gaps in the policy literature about how drug courts were created and how they evolved. Another focal point was determining how state-level actors such as legislators, state supreme courts, and bureaucratic agencies regulated drug court policy in each particular state. From this data, a continuum was formed to determine which states operated from a top-down management style for drug courts and which …

The Marvel Sonic Narrative: A Study Of The Film Music In Marvel's The Avengers, Avengers: Infinity War, And Avengers: Endgame, Anthony Walker

Graduate Theses, Dissertations, and Problem Reports (ETD)

This document explores the music of three films in the Marvel Avengers enterprise: Marvel’s The Avengers, Avengers: Infinity War, and Avengers: Endgame. It does not examine the second film of the series, Avengers: Age of Ultron. The document seeks to uncover and further understand the music’s function in each film and to determine its continuity throughout all three films. This study uses a combination of film music studies and theory-based analysis to support the findings with the aim of identifying connecting musical elements that stretch throughout these three films. This includes the use of leitmotif/themes, previously …

Evaluating The Consistency Of A Breathing Flow Recording Device Across Different Elastomeric Half-Mask Respirators, Samuel Jennings Munnis

Graduate Theses, Dissertations, and Problem Reports (ETD)

The National Institute of Occupational Safety and Health (NIOSH) is the organization in charge of approving respiratory devices in the United States, as permitted by 42 CFR Part 84. Standards that NIOSH uses to certify powered air-purifying respirators (PAPRs) are based on respiratory data collected before the 21^st century. With new technologies, it is possible to gain a more accurate understanding of breathing flow of healthcare workers (HCWs). A new portable breathing flow recording device developed by The S.E.A. Group was intended for use with a Sundström SR100 mask with a P100 filter. This study tests the device with …

Phased Array Feed Beamforming And Its Application In Mapping Extended Sources, Gargi Roy

Graduate Theses, Dissertations, and Problem Reports (ETD)

Ever since the detection of radio signals, technology has strived to improve the performance of the hardware associated with detecting and observing faint radio sources by improving signal processing and detection techniques. Phased array feeds (PAFs) for radio telescopes can yield in an increase in the survey speed and field of view for reflector antennas. Beamforming, calibration, and imaging are some of the challenges that need to be addressed in order to further the development of PAFs. There is a trade-off between achieving high sensitivity and maintaining a stable clean beam pattern when it comes to beamforming design strategies. A …

Pain Relief Knowledge, History, And Expectations Among Emergency Dental Patients, Daniel C. Brawley

Graduate Theses, Dissertations, and Problem Reports (ETD)

Introduction

Dentists frequently treat and manage patients with acute dental pain. Patients often seek care to treat their pain. As a part of that treatment, it is common for providers to use both prescription and non-prescription medications in the management of the patient’s dental pain. This study focused on understanding the patient’s knowledge, history and expectations regarding prescription and non-prescription medication in the management of their dental pain.

Methods

A self-report survey was developed, using Likert-type scales, consisting of 32 items, including standardized, psychometrically-tested instruments. The survey was administered to 108 adult outpatients who reported to the West Virginia University …

Review Of Water Allocation Models For West Virginia, Madison Lee Alexis Thompson

Graduate Theses, Dissertations, and Problem Reports (ETD)

Modeling river basins started gaining in popularity and usage in the western part of the United States in large part due to its extreme droughts. Planning is necessary to sustain the population, industries, and recreational water use year-round. Water allocation modeling is a tool used to aid in the issues that come from managing water resources. This work considers the continuous models that synthesized the hydrologic processes that occur and provides a simulation of past, current, or future conditions.

West Virginia, located on the eastern side of the United States, does not have an extreme drought problem as seen in …

Fundamental Mechanism Of Time Dependent Failure In Shale, Neel Gupta

Graduate Theses, Dissertations, and Problem Reports (ETD)

In underground coal mines, mining activity disturbs the natural equilibrium state of in-situ stresses. The induced and in-situ stresses deform the rockmass surrounding the mine openings. Primary roof supports impede the deformation of the rockmass overlying the entries. However, failure can occur in the bolted rockmass, causing fatalities and injuries. The rockmass failure is erratic, and its occurrence often varies from a few days to months and years after the opening of the entry. One of the often-neglected factors in this process is the effect of time on the stability of mine openings, which can often be observed in the …

Promoting Cognitive And Fine Motor Development In The Art Room For Young Students With Exposure To Trauma: An Exploratory Case Study., Tiffany Marie Minuci

Graduate Theses, Dissertations, and Problem Reports (ETD)

Despite the overwhelming research that suggests visual artmaking experiences can produce positive outcomes for individuals, many state art education policies fail to implement and integrate the arts into core academic curriculums. Specifically in the state of West Virginia, kindergarten through twelfth grade students often lack the access to a quality and consistent art education. With high teacher-pupil ratios and inclusive learning environments, educators face the difficult task of meeting all the individual needs of their students’ in the classroom. This not only affects whole student populations, but also poses risks for children who have been exposed to trauma. Traumatic experiences …

Utilization Of Scale In Keypoint Detection And Feature Description, Andrew P. Rhodes

Graduate Theses, Dissertations, and Problem Reports (ETD)

Ubiquitous availability of inexpensive three dimensional (3D) sensors has led to an abundance of keypoint detection and feature description techniques for point-clouds. While some recent methods utilize color along with geometric information, most only implicitly discuss -- if not completely disregard -- the information provided by scale. Scale is an inherent characteristic of any keypoint or feature that describes its physical size or region of support.

Exploiting information provided by scale facilitates the processes of keypoint detection and feature description. A 3D scale-space, extended from robust and popular 2D methods, is constructed to diffuse a signal on triangulated meshes. Methods …

Enabling Robust State Estimation Through Covariance Adaptation, Ryan Magnum Watson

Graduate Theses, Dissertations, and Problem Reports (ETD)

Several robust state estimation frameworks have been proposed over the previous decades. Underpinning all of these robust frameworks is one dubious assumption. Specifically, the assumption that an accurate a priori measurement uncertainty model can be provided. As systems become more autonomous, this assumption becomes less valid (i.e., as systems start operating in novel environments, there is no guarantee that the assumed a priori measurement uncertainty model characterizes the sensors current observation uncertainty).

In an attempt to relax this assumption, a novel robust state estimation framework is proposed. The proposed framework enables robust state estimation through the iterative adaptation of the …

Dispositional Empathy And Autonomic Reactivity During A Comfort Interaction, Alaina G. Tiani

Graduate Theses, Dissertations, and Problem Reports (ETD)

The purpose of the current study was to examine the association between dispositional (trait) empathy and autonomic reactivity during dyadic interactions among women enrolled in undergraduate psychology courses. The primary research question was: do individuals who are deemed higher in dispositional empathy according to self-report exhibit differential autonomic reactivity patterns during a task in which they are asked to comfort another student experiencing emotional distress than those who are deemed lower in dispositional empathy? The literature on this relation has been mixed and has utilized photos or videos to evoke emotion; thus this study sought to examine the relation between …

Folk-Song To Formal Performance: Interpreting The Songs Of Jean Ritchie For Voice Recital, Julianne E. Laird

Graduate Theses, Dissertations, and Problem Reports (ETD)

The purpose of this study was to identify the value of incorporating American folk-song into a formal voice recital program, specifically the collections and compositions of Jean Ritchie. This qualitative study identified criteria for choosing specific folk-songs to include in formal recital, assessed quality in a folk-song arrangement, discussed suitable instrumentation for accompaniment, and suggested appropriate performance practices for concert performance. New folk-song literature was discovered through accessing original unpublished sources in the American Folklife Center of the Library of Congress. Finally, a format and program for incorporating the collected and composed folk-songs of Jean Ritchie in formal recital was …