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Development And Validation Of An Oral Health Values Scale, Cierra B. Edwards Jan 2017

Development And Validation Of An Oral Health Values Scale, Cierra B. Edwards

Graduate Theses, Dissertations, and Problem Reports (ETD)

Oral health values, the degree to which one demonstrates investment in improving or maintaining one's dental status, are believed to vary across individuals. Oral health values may contribute to dental treatment utilization. By assessing differences in oral health values, researchers may be better able to explain differences in dental care treatment-seeking patterns. There is limited research, however, on measuring and evaluating oral health values. This study developed and validated a new Oral Health Values Scale (OHVS) that may be used in future research efforts to understand psychosocial barriers to treatment. The study provided evidence of content validity by having experts …


A Discussion Of Art Therapy Approaches Used In Classroom Activities To Help Students With Emotional And Behavioral Issues, Ashley Nichol Elliott Jan 2017

A Discussion Of Art Therapy Approaches Used In Classroom Activities To Help Students With Emotional And Behavioral Issues, Ashley Nichol Elliott

Graduate Theses, Dissertations, and Problem Reports (ETD)

The purpose of this paper was to inform the reader of the benefits of using art therapy activities in art lessons as a way to help students' process emotional and behavioral issues. New and future art educators are not equipped to handle the wide range of issues that students face everyday. This is especially true for the students in the West Virginia public school system. As in larger, more urban locations, many students here deal with drugs, violence, bullying, abuse, and others contemporary social stressors. In this paper, I utilized my own personal experiences, literary research, experimentation, and observations of …


Elementary Educators' Attitudes About The Utility Of Educational Robotics And Their Ability And Intent To Use It With Students, Todd I. Ensign Jan 2017

Elementary Educators' Attitudes About The Utility Of Educational Robotics And Their Ability And Intent To Use It With Students, Todd I. Ensign

Graduate Theses, Dissertations, and Problem Reports (ETD)

Educational robotics (ER) combines accessible and age-appropriate building materials, programmable interfaces, and computer coding to teach science and mathematics using the engineering design process. ER has been shown to increase K-12 students' understanding of STEM concepts, and can develop students' self-confidence and interest in STEM. As educators struggle to adapt their current science teaching practices to meet the new interdisciplinary nature of the Next Generation Science Standards, ER has the potential to simultaneously integrate STEM disciplines, engage and inspire students in mathematics and science, and build connections to STEM careers. One challenge is a lack of documented models for preparing …


Naval Diplomacy And The Making Of An Unwritten Alliance: United States-Brazilian Naval Relations, 1893-1930, Karina Faria Garcia Esposito Jan 2017

Naval Diplomacy And The Making Of An Unwritten Alliance: United States-Brazilian Naval Relations, 1893-1930, Karina Faria Garcia Esposito

Graduate Theses, Dissertations, and Problem Reports (ETD)

This dissertation explores U.S.-Brazilian relations through the prism of naval diplomacy between 1893 and 1930. Broadly, this dissertation explains the growth of U.S. naval involvement in Brazil, emphasizing the motives of Brazilian and American policymakers, and the role of naval officers in strengthening bilateral relations. This study begins by examining the Brazilian Navy Revolt of 1893-94, contextualizing it within the formative years of the Brazilian Republic, while discussing U.S. naval intervention in the conflict. It then explores U.S.-Brazilian naval relations in the early twentieth century, explaining the growing association between the two countries' navies after the turn of the century. …


Spread Of False News Stories On Facebook: An Assessment Of Credibility Cues And Personality, Lacie Geary Jan 2017

Spread Of False News Stories On Facebook: An Assessment Of Credibility Cues And Personality, Lacie Geary

Graduate Theses, Dissertations, and Problem Reports (ETD)

This study used a 2 x 2 method to examine the effectiveness of credibility cues on Facebook and how the personality traits neuroticism and openness impact sharing behaviors across cues of different shapes and colors. Findings suggested the color red increased cue noticeability, however, overall a low number of participants noticed any of the four varying cues across conditions, indicating that the fast-paced scrolling nature of online mediums prevents users from noticing credibility cues. Future research should examine the differences in pace of scrolling and information intake across different generations. This information might be useful to media outlets to help …


Open-Access Crime Maps As Digital Rhetoric And Crime Reporting In Chicago: Using New Aesthetic Overlaps To Change Journalism And Citizen Interaction, Aaron Geiger Jan 2017

Open-Access Crime Maps As Digital Rhetoric And Crime Reporting In Chicago: Using New Aesthetic Overlaps To Change Journalism And Citizen Interaction, Aaron Geiger

Graduate Theses, Dissertations, and Problem Reports (ETD)

When data mining meets the rhetoric of maps and crowdsourcing in the age of digital journalism, we can use the abundance of data to change, modify or reinforce particular reporting behaviors or journalism policies. We also live in an age of overlapping boundaries of technologies, algorithms and human interfaces---it is within these overlaps that we find anomalies, "glitches", and digital errata that can expose different perceptions of the same artifacts and algorithms. The overlapping of the heterogeneous network, as James Bridle calls it, is known as The New Aesthetic. It is not a movement, but "a series of artifacts ... …


The Effect Of A Leader's Emotional Intelligence On The Subordinate's Intention To Whistleblow, Xin Geng Jan 2017

The Effect Of A Leader's Emotional Intelligence On The Subordinate's Intention To Whistleblow, Xin Geng

Graduate Theses, Dissertations, and Problem Reports (ETD)

Two experiments in this dissertation examine the effect of a leader's emotional intelligence and its interaction with other constructs on the subordinate's intention to whistleblow. Results from the primary experiment indicate that when the leader is not involved in the observed accounting fraud, the subordinate is more likely to whistleblow to the leader if the leader has high emotional intelligence or high group prototypicality. The relationship between leader emotional intelligence and subordinate whistleblowing intention is stronger when the leader has high group prototypicality and is mediated by the subordinate's perceived leader-member exchange, trust in the leader, and job satisfaction. These …


Core Flight System Cryptography Library, John Patrick Lucas Jan 2017

Core Flight System Cryptography Library, John Patrick Lucas

Graduate Theses, Dissertations, and Problem Reports (ETD)

The NASA Independent Verification and Validation (IV&V) Program has been tasked with performing testing for the Consultative Committee for Space Data Systems (CCSDS) Space Data Link Security (SDLS) Extended Procedure (EP) protocol. This testing has allowed for both the expansion of inter-agency collaboration and the publishing of the SDLS-EP Standard. This protocol is a "data processing method for space missions that need to apply authentication and/or confidentiality to the contents of Transfer Frames used by the Space Data Link Protocols over a space link" (CCSDS) . The interest for security on satellites stems from threats including but not limited to …


Think Twice Before Hitting 'Send': The Strategic Uses Of Information In Marketing Channels, Pui Ying Tong Jan 2017

Think Twice Before Hitting 'Send': The Strategic Uses Of Information In Marketing Channels, Pui Ying Tong

Graduate Theses, Dissertations, and Problem Reports (ETD)

This dissertation examines the growing problem of information overload in the context of marketing channels. Information overload occurs when shared information requires more mental resources to process than the mental resources available to the receiver. This research offers strategies to attenuate information overload and examines the impact of information overload on channel outcomes. Strategic uses of information are proposed and conceptualized as a sender's alteration of information volume, content, and/or timing to assist a receiver in processing information. Hypotheses are developed based on the normative perspective of communication from the organizational communication literature. Data from 244 salespeople are analyzed using …


Biochemical Characterization Of The Release Of Fak Autoinhibition, Jessica E. Hall Jan 2017

Biochemical Characterization Of The Release Of Fak Autoinhibition, Jessica E. Hall

Graduate Theses, Dissertations, and Problem Reports (ETD)

Focal adhesion kinase is an essential nonreceptor tyrosine kinase that plays an important role in development, in homeostasis and in the progression of human disease. Multiple stimuli activate FAK, which requires a change in structure from an autoinhibited to activated conformation. In the autoinhibited conformation the FERM domain associates with the catalytic domain of FAK and PI(4,5)P2 binding to the FERM domain plays a role in the release of autoinhibition, activating the enzyme. This work aims to better characterize the residues involved in the release of the autoinhibitory conformation. The first aim was to characterize the effects of point mutations …


Stochastic Geometry Analysis Of A Class Of Cooperative Relaying Protocols, Sri Lakshmi Phani Balineni Jan 2017

Stochastic Geometry Analysis Of A Class Of Cooperative Relaying Protocols, Sri Lakshmi Phani Balineni

Graduate Theses, Dissertations, and Problem Reports (ETD)

This thesis examines wireless relay networks that use hybrid-ARQ protocols. Relays networks efficiently combat fading and exploit the spatial diversity present in the channel. Hybrid-ARQ involves retransmitting the signal if it is not decoded correctly. In conventional HARQ, the retransmission comes from the source, but in cooperative HARQ the retransmission could come from a relay that has successfully decoded the message, thus attaining transmit diversity.;A Markov chain model is conceived and used to compute the effective throughput and outage probability in the presence of Rayleigh fading. The analytical results are validated with simulations. The spatial configuration of the network plays …


Associations Between Sleep, Infant Feeding Methods, Brain Development And Behavior: A Multimodal Approach To Assess Plasticity In The Brain, Christopher Edward Bauer Jan 2017

Associations Between Sleep, Infant Feeding Methods, Brain Development And Behavior: A Multimodal Approach To Assess Plasticity In The Brain, Christopher Edward Bauer

Graduate Theses, Dissertations, and Problem Reports (ETD)

Purpose: Sleep-disordered breathing (SDB) is a spectrum disorder that is estimated to effect a significant proportion of the pediatric population (1-3% in USA). SDB is able to disrupt and fragment sleep through frequent arousals and intermittent hypoxia. In addition, the long term effects of SDB in pediatrics have been well-documented; decreases in intelligence quotient (IQ), executive function, school performance, and alertness have all been observed. Although surgical treatments can be quite effective, there are no widely accepted prophylactic measures to prevent SDB development. Recently, breastfeeding duration in infancy has been demonstrated to be correlated with reduced SDB (lower AHI, RAI, …


Interactions Between Euwallacea Ambrosia Beetles, Their Fungal Symbionts And The Native Trees They Attack In The Eastern United States, Matthew C. Berger Jan 2017

Interactions Between Euwallacea Ambrosia Beetles, Their Fungal Symbionts And The Native Trees They Attack In The Eastern United States, Matthew C. Berger

Graduate Theses, Dissertations, and Problem Reports (ETD)

In a globalized world, wood products are constantly being shipped from one location to another, along with tiny hitchhikers in the form of insects and microorganisms. Euwallacea validus is a fungus-farming ambrosia beetle native to East Asia that likely made its way to the United States in wood packaging materials in the latter half of the twentieth century. E. validus cultivates two fungal symbionts in the U.S., an unnamed Fusarium sp. (AF-4) and Raffaelea subfusca. Fusarium symbionts of Euwallacea ambrosia beetles as well as Raffaelea symbionts of closely related ambrosia beetles have incited widespread disease on more than one-hundred hosts …


Fluid Inclusion Analyses Of Bedded Halite From The Neoproterozoic Browne Formation Of Central Australia To Determine Parent Water Origin And Ph, Jeremiah A. Bernau Jan 2017

Fluid Inclusion Analyses Of Bedded Halite From The Neoproterozoic Browne Formation Of Central Australia To Determine Parent Water Origin And Ph, Jeremiah A. Bernau

Graduate Theses, Dissertations, and Problem Reports (ETD)

The depositional origin of the Neoproterozoic Browne Formation of Australia is unclear. The Browne Formation consists of red-siliciclastic mudstone and siltstone (red beds), bedded and displacive halite and gypsum, and dolomitized stromatolites. Environmental interpretations of the Browne Formation range from a marginal marine lagoon to a playa lake deposit (Grey and Blake, 1999; Hill et al., 2000; Haines et al., 2004; Spear, 2013).;Primary fluid inclusions in Browne Formation bedded halite are the oldest known surface water remnants (Spear et al., 2014). Prior major-ion ratio analysis of these inclusions indicates that the Browne Formation formed from waters with unusually low sulfate …


A Low-Power Optoelectronic Characterizer For Cubesat: Locc And Iii-V Nitride Based Leds, Matthew J. Pachol Jan 2017

A Low-Power Optoelectronic Characterizer For Cubesat: Locc And Iii-V Nitride Based Leds, Matthew J. Pachol

Graduate Theses, Dissertations, and Problem Reports (ETD)

III-V semiconductor materials exhibit robustness and natural hardness when exposed to ionizing radiation and temperature swings. With these characteristics in mind, III-V Nitride Light Emitting Diodes (LEDs) are ideal devices for space-based applications and missions. The effects of ionizing radiation on optoelectronic devices comprised of III-V materials have been studied, but results have been obtained through experiments performed in terrestrial laboratories. While these laboratory tests may lend insight into device lifetimes, performance degradation, etc., they are no substitute for similar measurements and characterization performed in space.;Interest in small satellite applications have grown over the past decade. These solutions range from …


Are Title V Grants And Educational Expenditures Associated With Educational Attainment Of Latinasos At Hispanic Serving Institutions? = Estan Las Subvenciones Del Program Federal Title V Y Gastos En Educacion (Instruccion, Apoyo Academico, Y Servicios A Lasos Estudiantes) Relacionados Con Los Logros Educacionales De Lasos Latinasos En Las Instituciones De Estudios Superiores Que Serving A Lasos Latinasos (Hsi)?, Ligia Perez Jan 2017

Are Title V Grants And Educational Expenditures Associated With Educational Attainment Of Latinasos At Hispanic Serving Institutions? = Estan Las Subvenciones Del Program Federal Title V Y Gastos En Educacion (Instruccion, Apoyo Academico, Y Servicios A Lasos Estudiantes) Relacionados Con Los Logros Educacionales De Lasos Latinasos En Las Instituciones De Estudios Superiores Que Serving A Lasos Latinasos (Hsi)?, Ligia Perez

Graduate Theses, Dissertations, and Problem Reports (ETD)

The purpose of this study is to determine if Title V HSI grants and expenditures in instruction, academic support, and student services at 4-year Hispanic Serving Institutions (HSIs) account for observed differences in the graduation rates of Latinas/os and the percent of bachelor's degree completions of Latina/o students, and whether HSIs are equitable in the proportion of bachelor's degrees awarded to Latinas/os. HSIs are colleges and universities that enroll 25% or more full time equivalent (FTE) undergraduate Latina/o students. In general, the purpose of the federal Title V HSI grant is to fund programs to enhance the educational attainment of …


Exploring Concentration And Duration Dependence In Hormesis, Maren S. Prediger Jan 2017

Exploring Concentration And Duration Dependence In Hormesis, Maren S. Prediger

Graduate Theses, Dissertations, and Problem Reports (ETD)

The phenomenon of hormesis, characterized by beneficial low-exposure stress-protective effects, has experienced increasing interest by the scientific community. Elucidating the underlying cellular signaling pathways that lead to a new homeostatic state can provide crucial information about new therapeutic targets to prevent and treat diseases. Commonly investigated for hormetic behavior are plant-based substances (phytochemicals), such as quercetin, epigallocatechin gallate, curcumin, and resveratrol. The polyphenol resveratrol, found in peanuts, grapes, and subsequently in wine, is known for a variety of effects---beneficial and detrimental---depending on the investigated cell type and concentration. In HepG2 cells, an increase in proliferation has been observed previously at …


Far-Field Ground Strain Failure Mode Assessment For Mineral Extraction Near Dams, Harold Russell Jan 2017

Far-Field Ground Strain Failure Mode Assessment For Mineral Extraction Near Dams, Harold Russell

Graduate Theses, Dissertations, and Problem Reports (ETD)

Steeply sloped, high relief landforms with fractured sedimentary geology in proximity to underground mine voids have the potential to produce far-field ground strains which initiate strain failure modes for cross valley dams. The Ryerson Station Dam breach in 2005 brought attention to the possibility of increased hazard to dams due to far-field ground strain phenomena from underground mining.;The mapping study found that three United States Army Corps of Engineers (U.S.ACE) owned and operated dams were within the 1-mile buffer radius, and four within the 2.7-mile buffer radius of mine permits in West Virginia. Some U.S.ACE dams can be very large …


The Potential Impact Of Art Therapy Approaches In An Alternative Learning School Setting In Urban West Virginia, Brianna Saddler Jan 2017

The Potential Impact Of Art Therapy Approaches In An Alternative Learning School Setting In Urban West Virginia, Brianna Saddler

Graduate Theses, Dissertations, and Problem Reports (ETD)

Now more than ever American adolescents are suffering from severe anxiety (Lewis, 2017). In the past, over-achieving students were those parents least worried about when it came to experiencing anxiety but now studies show these students are just as likely to experience anxiety as those learners considered to be underachievers. The purpose of this paper is to inform the reader how art therapy approaches embedded into daily lesson plans could be used in alternative learning school settings to help students deal with anxiety. Through my own experiences as a practicing art teacher in both general education art classrooms and alternative …


Effect Of The Cpap-Saver Intervention On Adherence Among Adults With Newly Diagnosed Obstructive Sleep Apnea, April L. Shapiro Jan 2017

Effect Of The Cpap-Saver Intervention On Adherence Among Adults With Newly Diagnosed Obstructive Sleep Apnea, April L. Shapiro

Graduate Theses, Dissertations, and Problem Reports (ETD)

Introduction: Obstructive sleep apnea (OSA) affects 25 million adults in the United States. Continuous positive airway pressure (CPAP) is the treatment of choice, but adherence is poor. Many previous CPAP adherence interventions were not theory based, tended to impose time and cost burden, and did not focus on OSA airway-brain mechanism education or OSA-CPAP performance feedback. A new, multidimensional intervention, known as CPAP-SAVER, was developed, based on the Theory of Planned Behavior (TPB), knowledge of CPAP facilitators and barriers, characteristics of CPAP adherers and nonadherers, and behavior change techniques. The purpose of this study was to examine the effect of …


North-East Indian Monsoon Rainfall Variability Over Southeastern Peninsular India, Jothiganesh Shanmugasundaram Jan 2017

North-East Indian Monsoon Rainfall Variability Over Southeastern Peninsular India, Jothiganesh Shanmugasundaram

Graduate Theses, Dissertations, and Problem Reports (ETD)

North-East Indian Monsoon rainfall (NEIMR) during October-December is of immense socio-economic importance to the agriculture dependent population in the southeastern peninsular India. NEIMR is subject to extreme year-to-year and intra-seasonal variability that needs to be understood to enhance climate resilience. An understanding of NEIMR variability and the physical processes behind this variability would help to improve the predictability of NEIMR variation over the southeastern peninsular of India. An insight into past societal responses to monsoon variability would be a great lesson for adapting to future climate challenges. This dissertation seeks to examine the intra-seasonal variability of NEIMR and its driving …


Substrate Nanotopography And Stiffness Modulation Of Cell Behaviors For Disease Detection And Modeling, Lin Shi Jan 2017

Substrate Nanotopography And Stiffness Modulation Of Cell Behaviors For Disease Detection And Modeling, Lin Shi

Graduate Theses, Dissertations, and Problem Reports (ETD)

In most living tissue, cells resident in a complex microenvironment where these cells interact with the extracellular matrix (ECM) and the neighboring cells. The interactions between cells and ECM could regulate the cell behavior. Similar to in vivo, in vitro models have been reported that cells have the ability to sense the nanotopography and stiffness of synthetic substrate and, the variation of substrate nanotopography configuration and stiffness could affect cell phenotype and function.;The first project focused on applying nanotopography to capture circulating tumor cells (CTCs) for early cancer detection. CTCs shed from primary tumors, transport through the bloodstream to distant …


Approaches To Supervision In Sport Psychology And Their Influences On Initial Supervisees' Professional Development, Janaina Lima Fogaca Jan 2017

Approaches To Supervision In Sport Psychology And Their Influences On Initial Supervisees' Professional Development, Janaina Lima Fogaca

Graduate Theses, Dissertations, and Problem Reports (ETD)

Supervision is important to foster supervisees' development, protect their clients from harm, and ensure competence. Sport psychology graduate programs in the United States offer a variety of supervision approaches, but there are few official guidelines on how to supervise. This dissertation had the aim of investigating the supervision approaches being used with novice supervisees in applied sport psychology in the United States, and how these approaches relate to supervisees' development of service-delivery competence. Nine supervisor-supervisee dyads were interviewed before and after the academic term in which the supervisees had their first applied experiences. Supervisees completed two journal entries regarding their …


Early Feeding Experiences Of Families Whose Children Were Born With Cleft Lip Andor Palate: A Rural Perspective, Meghan Snyder Jan 2017

Early Feeding Experiences Of Families Whose Children Were Born With Cleft Lip Andor Palate: A Rural Perspective, Meghan Snyder

Graduate Theses, Dissertations, and Problem Reports (ETD)

An initial problem frequently found in children born with cleft palate is difficulty feeding. This problem can be magnified in rural areas where healthcare resources are limited. A 29-item questionnaire was developed and administered to 24 families whose children were born with a cleft palate. Many parents experienced difficulties in both instruction and in feeding their children. It was necessary for them to seek information and assistance from different sources. As a result of the findings, an informational pamphlet was developed and distributed to various rural hospitals located in West Virginia, so that information and sources of instruction for feeding …


Noncoherent Physical-Layer Network Coding With Frequency-Shift Keying Modulation, Terry Ferrett Jan 2017

Noncoherent Physical-Layer Network Coding With Frequency-Shift Keying Modulation, Terry Ferrett

Graduate Theses, Dissertations, and Problem Reports (ETD)

The rapid growth of wireless communication technology has motivated novel approaches into improving performance. A major avenue of research investigates the benefit of relaying, where wireless devices outside radio range of each other communicate by passing information through a device in between. Traditionally, devices communicating through a relay transmit at separate times to avoid interfering with each other. Physical-layer network coding is a recent technique that improves throughput by allowing devices to transmit at the same time to the relay, deliberately interfering. This dissertation develops a system performing physical-layer network coding in the topology where two devices exchange information through …


Black-Legged Tick Distributions, Small Mammal Abundances, Mast Production, And Vegetative Influences On Lyme Disease Apparent Prevalence On Fort Drum Military Installation, New York, Samantha R. Fino Jan 2017

Black-Legged Tick Distributions, Small Mammal Abundances, Mast Production, And Vegetative Influences On Lyme Disease Apparent Prevalence On Fort Drum Military Installation, New York, Samantha R. Fino

Graduate Theses, Dissertations, and Problem Reports (ETD)

Lyme disease is the most common infectious disease spread by black-legged ticks in the Northern Hemisphere. Lyme disease is a vector-borne zoonotic disease typically caused by bacterial spirochetes of the species Borrelia burgdorferi. The primary vector of Lyme disease in the Midwestern and eastern United States is Ixodes scapularis, the deer or black-legged tick. Although there are several preventative measures against ticks that carry Lyme disease, such as public education regarding personal protection (e.g., wearing light colored clothing, tucking pants into socks, wearing repellent, promptly inspecting oneself to remove ticks, getting pets vaccinated) and recommended control measures, it is important …


The Relationship Between Father Involvement And Paternal Emotion Socialization, Kayla E. Forshee Jan 2017

The Relationship Between Father Involvement And Paternal Emotion Socialization, Kayla E. Forshee

Graduate Theses, Dissertations, and Problem Reports (ETD)

The purpose of this study was to examine the relationship between father involvement and emotion socialization. Fathers amount of time and quality of paternal involvement (e.g., engagement in childcare activities, secondary activities, and time spent in children's company) with their preschool aged children was assessed to determine if it influenced how fathers respond to the children's emotion (e.g., disappointment, anger, and anxiety). Heterosexual fathers (M = 39.46 yrs.) of children ages 3-5 years old were recruited from preschools and daycares in the larger metropolitan, D.C. area. Paternal self-report measures were used to measure father's involvement and their socialization strategies. Results …


Development And Evaluation Of A Patient Decision Aid For The West Virginia Physician Order For Scope Of Treatment (Post), Jarred V. Gallegos Jan 2017

Development And Evaluation Of A Patient Decision Aid For The West Virginia Physician Order For Scope Of Treatment (Post), Jarred V. Gallegos

Graduate Theses, Dissertations, and Problem Reports (ETD)

Decision aids have been shown to be helpful for patients making medical decisions. The use of decision aids can increase patient knowledge, decrease decisional conflict, and increase overall satisfaction with the treatment decision made. The purpose of the study was to develop and evaluate a novel video decision aid for the West Virginia Physician Orders for Scope of Treatment (POST). There are no known decision aids developed to assist patients completing POST forms, thus there is a paucity of research investigating the nature, quality, and outcomes of the decision-making process of patients completing a POST form. Fifty English-speaking, community-dwelling older …


Characterization Of The Immune Response To Lipopolysaccharide In Early Pregnant Ewes As A Model To Study Bacterial Infection Induced Embryonic Loss, Jessalyn Marie Hadfield Jan 2017

Characterization Of The Immune Response To Lipopolysaccharide In Early Pregnant Ewes As A Model To Study Bacterial Infection Induced Embryonic Loss, Jessalyn Marie Hadfield

Graduate Theses, Dissertations, and Problem Reports (ETD)

An immunological balance has to be established during pregnancy that protects the mother yet tolerates the semi-allogenic fetus. To understand the innate immune response during bacterial infections that may cause early embryonic loss, a lipopolysaccharide (LPS) treated sheep model was used. Two objectives of this study were to examine if omega-3 PUFAs in the form of supplementary whole flaxseed could reduce the inflammatory response to an LPS challenge and to examine if there is a differential immune response to LPS in Suffolk and Dorset ewes. A total of 3 experiments were conducted; two investigating the effect of supplement and one …


Investigating Stress Response Across Integrated Biological Systems, Alice A. Han Jan 2017

Investigating Stress Response Across Integrated Biological Systems, Alice A. Han

Graduate Theses, Dissertations, and Problem Reports (ETD)

The impact that a stressor has on a living system, whether it is on a cellular, organ, or even a whole organism level, can affect the overall health of the system. Monitoring the biochemical response resulting from a stressful experience offers insight into the numerous potential outcomes ranging on the spectrum of survival and death. Accessing this information not only provides a heightened understanding of the biochemical adaptions that occur, but also allows for the development of prediction models (to assess prospective influences of the stressor) or potential therapeutic treatments (to alleviate adverse effects) using measurable, quantifiable, and comparable metrics. …