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The Persistence Of Radiation-Induced Chromosome Aberrations In Mice., Michelle Denise Spruill Jan 1997

The Persistence Of Radiation-Induced Chromosome Aberrations In Mice., Michelle Denise Spruill

Graduate Theses, Dissertations, and Problem Reports (ETD)

As translocations increase in popularity for use as a biodosimeter for prior radiation exposure, information on the possible decline of these 'stable' aberrations over time is desperately needed. This study is the first to assess the stability of radiation-induced chromosome aberrations in vivo over the life span of a rodent model. C57BL/6 female mice were given an acute dose of 0, 1, 2, 3 or 4 Gy {dollar}\\sp{lcub}137{rcub}{dollar}Cs of 8 weeks of age. Metaphase chromosome preparations were made from peripheral blood and bone marrow samples which were taken from 4 mice in each dose group at 1, 8, 15 and …

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The Ecology Of Darters In The Elk River, West Virginia., Stuart Andrew Welsh Jan 1997

The Ecology Of Darters In The Elk River, West Virginia., Stuart Andrew Welsh

Graduate Theses, Dissertations, and Problem Reports (ETD)

The darter fauna in the Elk River, West Virginia, is extremely diverse (18 species); however, few studies exist on its ecology. This dissertation, which consists of three manuscripts, provides data on the ecology of darters within the Elk River. In the first manuscript, I estimated allozyme variation in the Tippecanoe (Etheostoma tippecanoe) and golden (Etheostoma denoncourti) darters, fishes with extremely fragmented distributions. Despite our findings of low variation at 22 loci, frequency differences at Pgm and Pgdh separated E. tippecanoe and E. denoncourti. The second manuscript is a study of microhabitat use and partitioning in ten darter species. While snorkeling, …

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Physical, Chemical, And Microbial Analysis Of Domestic Wastewater Treated By Small Constructed Wetlands Designed For Individual Households., Keith R. Hench Jan 1997

Physical, Chemical, And Microbial Analysis Of Domestic Wastewater Treated By Small Constructed Wetlands Designed For Individual Households., Keith R. Hench

Graduate Theses, Dissertations, and Problem Reports (ETD)

Many small communities located in rural areas of the United States lack adequate domestic wastewater treatment plants. Constructed wetlands are being promoted as low-cost, low-maintenance systems for treatment of domestic wastewater in areas where standard septic tanks fail. In order to evaluate the efficacy of small constructed wetlands, 20 small-scale wetlands mesocosms (100 gal each) containing five plant treatments (no plants/control, Typha, Scirpus, and Juncus monocultures, and all three species combined) were planted into pea gravel at either 18 or 24 inches in depth. Each mesocosm received 5 gal/day of primary-treated domestic sewage. Mesocosms were monitored on a monthly basis …

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Modulation Of Nociception By The Opioid Peptide Beta-Endorphin In The Periaqueductal Gray., Alyssa A. Hawranko Jan 1997

Modulation Of Nociception By The Opioid Peptide Beta-Endorphin In The Periaqueductal Gray., Alyssa A. Hawranko

Graduate Theses, Dissertations, and Problem Reports (ETD)

Antinociceptive and nociceptive responses can be elicited by the administration of endorphin within the periaqueductal gray region of the midbrain. The pain inhibitory and facilitory systems exist in a state of balance such that under most conditions, the combined activation of these processes by the administration of -endorphin results in the expression of antinociception. However, during other situations, such as stress, the delicate balance between these endogenous systems is disrupted and alterations in the overall response to opioids occurs. When stress is minimized the contribution of the -endorphin dependent pain facilitory systems is minimal and cannot be discriminated unless a …

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Computer Programming: Science, Art, Or Both?, Sandra Trent Gum Jan 1997

Computer Programming: Science, Art, Or Both?, Sandra Trent Gum

Graduate Theses, Dissertations, and Problem Reports (ETD)

The purpose of this study was to determine if spatial intelligence contributes to a student's success in a computer science major or if mathematical-logical intelligence is sufficient data on which to base a prediction of success. The study was performed at a small university. The sample consisted of 15 computer science (CS) majors, enrolled in a computer science class, and 15 non-CS-majors, enrolled in a statistics class. Seven of the CS-majors were considered advanced and seven were considered less advanced. The independent measures were: the mathematics and the English scores from the ACT/SAT (CS-majors); a questionnaire to obtain personal information; …

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Regulation Of The Rpos Sigma Factor In Salmonella Typhimurium By Host Factor I, A Small Rna Binding Protein Encoded By Thehfq Gene., Larissa Carol Brown Jan 1997

Regulation Of The Rpos Sigma Factor In Salmonella Typhimurium By Host Factor I, A Small Rna Binding Protein Encoded By Thehfq Gene., Larissa Carol Brown

Graduate Theses, Dissertations, and Problem Reports (ETD)

We have found that Host Factor I (HF-I), the product of the hfq gene, is required for efficient expression of the RpoS stationary phase sigma factor in Salmonella typhimurium. HF-I is an RNA-binding protein originally characterized for its role in replication of phage Q{dollar}\\beta{dollar} of E. coli. Its role in the uninfected bacterial cell has previously been unknown. Assays of {dollar}\\beta{dollar}-galactosidase in strains with rpoS-lac fusions, Western blot analysis, and pulse-labeling and immunoprecipitation of both fusion proteins and native RpoS show that an hfq mutant has a four- to seven-fold reduction in the translation of rpoS. Suppressor mutations were isolated …

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The Control Of Human Placental Vascular Tone: I. The Effects Of Caffeine And Nicotine. Ii. The Role Of Progesterone., Rolando Juan Ramirez Jan 1997

The Control Of Human Placental Vascular Tone: I. The Effects Of Caffeine And Nicotine. Ii. The Role Of Progesterone., Rolando Juan Ramirez

Graduate Theses, Dissertations, and Problem Reports (ETD)

This dissertation is composed of two topics that share the focus of placental vascular tone control. In the first investigations, we looked at the effect of caffeine (Caff; 10nmol/L-10{dollar}\\mu{dollar}mol/L), nicotine (Nic), and cotinine (Cot) (1nmol/L-100{dollar}\\mu{dollar}mol/L for both) administration on isolated placental blood vessels, to see if these substances altered placental vascular tone. We found that moderate relaxations were initiated by all three alkaloids in precontracted placental blood vessels. We also found that pretreatment of placental blood vessels and Caff, Nic, and Cot did not alter responses to a variety of contractile agents. In conclusion, it would seem that the adverse …

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The Immunotoxic Effects Of A Herbicide, 3,4-Dichloropropionanilide, On Murine Macrophage Cytokine Production., Yilin Cindy Xie Jan 1997

The Immunotoxic Effects Of A Herbicide, 3,4-Dichloropropionanilide, On Murine Macrophage Cytokine Production., Yilin Cindy Xie

Graduate Theses, Dissertations, and Problem Reports (ETD)

Propanil (3,4-dichloropropionanilide) is a herbicide that is used for post-emergence control of weeds on rice, wheat, and potato production in the United States. The first hypothesis of our study is: propanil significantly inhibits cytokine production by macrophages which may contribute to its overall immunotoxicity. We demonstrate that i.p. propanil exposure significantly inhibited IL-6, TNF-{dollar}\\alpha{dollar} and IL-1{dollar}\\beta{dollar} production by macrophages. Acute oral exposure with propanil demonstrates that both 3 and 7 day post-exposure cytokine production by macrophages was reduced. However, only 7 day post-exposure with the primary metabolite of propanil, 3,4-dichloroaniline (DCA), resulted in the inhibition of cytokine production. Therefore, we …

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Changes In Arteriolar Structure And Function During Rapid Juvenile Growth., James Russell Linderman Jan 1997

Changes In Arteriolar Structure And Function During Rapid Juvenile Growth., James Russell Linderman

Graduate Theses, Dissertations, and Problem Reports (ETD)

Using a combination of in-vitro and in-vivo experimental techniques, the maturational changes in arteriolar structure and blood flow regulation were explored in the spinotrapezius muscle of weanling, juvenile and mature rats. In the first study, morphometric analysis of the arteriolar network architecture revealed that mean arcade segment length and arcade loop circumference had significantly increased from weanling to mature groups, whereas total number of arcade arteriole segments remained fairly constant. The number of transverse arteriole subnetworks per muscle remained constant from weanling to mature rats, but there were significant increases in total number of vessels in each branch order, total …

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Post-Soviet Transitions In Policy And Management Of Zapovedniki And Lespromkhozi In Central Siberia., David Miller Ostergren Jan 1997

Post-Soviet Transitions In Policy And Management Of Zapovedniki And Lespromkhozi In Central Siberia., David Miller Ostergren

Graduate Theses, Dissertations, and Problem Reports (ETD)

Dissolution of the Soviet Union in 1991 changed the government bureaucracy and dismantled the centrally controlled economic system. Directors of zapovedniki (strict nature preserves) and lespromkhozi (forest industry dependent communities) are experiencing a challenge to their ability to manage, protect and/or study the lands under their supervision. This study investigates how changes in the social-political system have affected the forests and protected areas in Central Siberia, and how managers have adapted to the current political and social climate. This investigation used case study methodology and three sources of empirical data; open-ended interviews, documentation from archival and secondary sources, and personal …

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Monte Carlo Studies Of Instabilities In Solids Under External Strains And Stresses., Anatoli M. Peredera Jan 1997

Monte Carlo Studies Of Instabilities In Solids Under External Strains And Stresses., Anatoli M. Peredera

Graduate Theses, Dissertations, and Problem Reports (ETD)

We use dynamical Monte Carlo simulations to investigate instabilities of solids in the presence of externally applied stresses or strains. One of the instabilities is the classical Euler buckling instability of compressed rods. We address, for the first time, the dynamical aspects of this instability, that is, we study how an initially straight flexible chain reaches the final buckled configuration at long times. We find that this process has much in common with coarsening phenomena such as the spinodal decomposition or unstable mound growth in molecular beam epitaxy. Evolving chain's profile is like a wave with a wavelength which grows, …

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Conceptual Knowledge Of A Normative Life Event: The Impact Of Intellectual Ability, Age, Experience And Attachment On The Concept Of Death., Elizabeth Rooney Levelle Jan 1997

Conceptual Knowledge Of A Normative Life Event: The Impact Of Intellectual Ability, Age, Experience And Attachment On The Concept Of Death., Elizabeth Rooney Levelle

Graduate Theses, Dissertations, and Problem Reports (ETD)

The present study investigated differences in the conceptualization of death among children and adults with and without mental retardation (MR). Thirty-five adults (17 adults without MR, 18 adults with MR) and 29 children (21 children without MR, 8 children with MR) participated in the study. The study employed a 2 x 2 design with Age and MR as the factors. Participants completed several questionnaires, cognitive developmental tasks, and intelligence assessments. Results indicated that diagnosis of mental retardation was slightly more influential than chronological age in determining participants' responses about death. This effect was evident for the Universality and Causality components …

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The Effect Of Estrogen On The Transcriptional Regulation And The Chromatin Remodeling Of The Very Low Density Apolipoprotein Ii Gene., Elizabeth Mambo Jan 1997

The Effect Of Estrogen On The Transcriptional Regulation And The Chromatin Remodeling Of The Very Low Density Apolipoprotein Ii Gene., Elizabeth Mambo

Graduate Theses, Dissertations, and Problem Reports (ETD)

The chicken very low density apolipoprotein II (apoVLDLII) gene encodes an egg yolk protein that is synthesized in the liver in response to estrogen. Regulation of this gene is mediated by the estrogen receptor via two estrogen response elements (EREs) located in the promoter. Following the administration of estrogen, there is a four hour lag period prior to the detection of apoVLDLII mRNA. To examine the events that occur during this lag period, in vivo footprinting and run-on transcription assays were performed. Time courses of the transcription of the apoVLDLII gene were done using the transcription run-on assay. The antisense …

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A Neural Network Based Inference Engine Generator For Comprehension And Translation Of English And Spanish Commands To Unix "E-Mail" And "Vi" Editor., Mohammad Reza Moozoun Jan 1997

A Neural Network Based Inference Engine Generator For Comprehension And Translation Of English And Spanish Commands To Unix "E-Mail" And "Vi" Editor., Mohammad Reza Moozoun

Graduate Theses, Dissertations, and Problem Reports (ETD)

Since the advent of computers, scientists have tried to use the human languages for communication with computers. This pursuit has led several scientists, such as Chomsky to establish that there must be a specific part of the brain adapted to language learning and processing genetically, namely the "language organ". Humans are able to understand and produce sentences that they may have never heard. This leads to the understanding that language must follow some strict rules of processing which is referred to as "grammar of a language". The Artificial Neural Networks (NN) inspired by the neural networks of biological systems have …

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A Proposed Animal Model Of Clomipramine-Induced Posttraumatic Stress Disorder., Linda Louise Beeler Jan 1997

A Proposed Animal Model Of Clomipramine-Induced Posttraumatic Stress Disorder., Linda Louise Beeler

Graduate Theses, Dissertations, and Problem Reports (ETD)

Clomipramine (CLI) administered to neonatal rats has been purported to induce behavioral abnormalities in adulthood analogous to human endogenous depression (Vogel et al., 1990). Based on recent findings (e.g., Beeler, 1994; Goodman, Beeler, & Birkle, 1995), wherein CLI animals were shown to have neurobiological correlates distinct to humans diagnosed with posttraumatic stress disorder (PTSD), the current study was proposed to investigate whether CLI induced alterations might be more analogous to, and a model for, PTSD. The activity of CLI and saline control (SAL) rats across late adolescence through early adulthood (i.e., 2-, 4-, and 6 months of age) was examined …

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Effects Of Pattern Of Fsh On Follicular Growth And Ovulation And Relationships Between Histamine And Plasminogen Activator In The Ovulatory Process Of Gilts., David Jeffrey Wright Jan 1997

Effects Of Pattern Of Fsh On Follicular Growth And Ovulation And Relationships Between Histamine And Plasminogen Activator In The Ovulatory Process Of Gilts., David Jeffrey Wright

Graduate Theses, Dissertations, and Problem Reports (ETD)

Whether growth of large, ovulatory follicles differed after different modes of stimulation with FSH and whether growth was enhanced by exogenous LH were examined in prepubertal gilts. Gilts received either a single injection of 2 mg FSH at 0 h (SUPER-OV; AUSA International, Inc., Tyler, TX) or injections every 8 h (18 mg over 64 h) and either 10 {dollar}\\mu{dollar}g porcine LH (USDA-pLH-B2; Animal Hormone Program, Beltsville, MD.) with the first injection of FSH (n = 4 and 3, respectively) or no LH (n = 3 each). Number of follicles {dollar}\\geq{dollar}7 mm in diameter and ovarian weight did not differ …

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A Comparative Study Of The Development Of Educational Psychology In China And America., Huiping Liu Cervenka Jan 1997

A Comparative Study Of The Development Of Educational Psychology In China And America., Huiping Liu Cervenka

Graduate Theses, Dissertations, and Problem Reports (ETD)

Some people argue that Western psychology and Asian psychology are fundamentally different and irreconcilable. Western psychology is scientific and analytic-reductionistic, while Asian psychology is concerned with man's harmony{dollar}\\...{dollar} (in Paranjpe et al, 1988, p18). This study examines and compares the scientific roots of Western psychology and the humanistic roots of Asian psychology in an attempt to determine commonality between Chinese and American educational psychology. A historical comparative method is used in this study. Two approaches, the personalistic and the naturalistic are employed to examine the development of educational psychology in China and America. Results show that Western psychology has been …

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Aclassical Features Of Propranolol Pharmacokinetics., Carol Lynn Cronenberger Jan 1997

Aclassical Features Of Propranolol Pharmacokinetics., Carol Lynn Cronenberger

Graduate Theses, Dissertations, and Problem Reports (ETD)

Propranolol is a {dollar}\\beta{dollar}-adrenergic receptor blocking agent that has traditionally been administered for a number of clinical conditions. Although not as commonplace today, it still has significant clinical relevance. More importantly, however, is the large body of knowledge that has been generated which addresses the pharmacokinetic and pharmacodynamic characteristics of this {dollar}\\beta{dollar}-blocker. Indeed, propranolol has often been considered a model compound representative of other basic, lipophilic drugs which include narcotic analgesics, calcium-channel blockers, phenothiazines, and tricyclic antidepressants. For these reasons, we used propranolol in the studies reported in this disseration. One of our goals was to examine the capacity of …

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Herbicide Cross Resistance In Atrazine-Resistant Velvetleaf (Abutilon Theophrasti) And Redroot Pigweed (Amaranthus Retroflexus)., M Essam Dabaan Jan 1997

Herbicide Cross Resistance In Atrazine-Resistant Velvetleaf (Abutilon Theophrasti) And Redroot Pigweed (Amaranthus Retroflexus)., M Essam Dabaan

Graduate Theses, Dissertations, and Problem Reports (ETD)

Plant species that develop resistance to one herbicide (e.g., s-triazine) may simultaneously exhibit resistance to other herbicides to which they have never been exposed. The objectives of this study were to compare the response of atrazine resistant and susceptible biotypes of redroot pigweed (Amaranthus retroflexus L.) and velvetleaf (Abutilon theophrasti Medic.) to the herbicides alachlor (2-chloro-N-(2,6-diethylphenyl-N-(methoxymethyl) acetamide), atrazine (6-chloro-N-ethyl-{dollar}N\\sp\\prime{dollar}-(1-methyl-ethyl)-1,3,5-triazine-2, 4-diamine), linuron ({dollar}N\\sp\\prime{dollar}-(3,4-dichloro-phenyl)-N-methoxy-N-methylurea), and metribuzin (4-amino-6-(1,1-dimethylethyl)-3-(methylthio)-1,2,4-triazin-5 (4H)-one). Cross-resistance and competitive fitness were also determined, with and without the herbicides. Three experiments were conducted with resistant and susceptible biotypes of each species under controlled conditions. First, seeds were germinated at 3 temperatures …

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Cell-Specific Regulation Of Transcription Of The Malic Enzyme Gene. Characterization Of The Cis-Acting Elements That Modulate Nuclear T3 Receptor Activity., Xuexun Fang Jan 1997

Cell-Specific Regulation Of Transcription Of The Malic Enzyme Gene. Characterization Of The Cis-Acting Elements That Modulate Nuclear T3 Receptor Activity., Xuexun Fang

Graduate Theses, Dissertations, and Problem Reports (ETD)

Stimulation of malic enzyme transcription by triiodothyronine (T3) is robust ({dollar}>{dollar}60-fold) in chick embryo hepatocytes, weak (5-fold) in chick embryo fibroblasts that stably overexpress the nuclear T3 receptor-{dollar}\\alpha,{dollar} and still weaker (1-fold) in chick embryo fibroblasts which contain nuclear T3 receptor levels that are similar to those of CEH. Directed by the DNase I hypersensitive regions in the malic enzyme gene, functional transfection and in vitro DNA-binding analyses were performed and four cis-acting elements were identified in the malic enzyme 5{dollar}\\sp\\prime{dollar}-flanking DNA. These four cis-acting elements confer differences in nuclear T3 receptor activity between chick embryo hepatocytes and chick …

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Oligopsony Elements In The Recycled Wastepaper Market: Existence And Implications., Aref Aghaei-Hervani Jan 1997

Oligopsony Elements In The Recycled Wastepaper Market: Existence And Implications., Aref Aghaei-Hervani

Graduate Theses, Dissertations, and Problem Reports (ETD)

Old newspaper (ONP) is the largest single component (14%) of total U.S. Municipal Solid Waste (MSW). The rising problems associated with disposal of MSW in landfills can be dealt with if the volume of the waste stream is reduced by recycling. The wastepaper recycling market, in particular ONP, has not been successful in utilizing the ONP generated. The existence of high sunk costs for entry into deinking market, along with the small numbers of buyers in the ONP market were identified as reasons that the ONP market had oligopsony elements. This research examined oligopsony in the ONP market and its …

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Portrayal Of Teacher Image: An Exploration Of Perceptions And Behaviors Of Healthcare Educators., Carole Shockey Thomassy Jan 1997

Portrayal Of Teacher Image: An Exploration Of Perceptions And Behaviors Of Healthcare Educators., Carole Shockey Thomassy

Graduate Theses, Dissertations, and Problem Reports (ETD)

The purpose of this study was to explore and describe the image healthcare educators believed they portrayed as a teacher and the behaviors they believed actualized the image. A pilot study was completed to evaluate the data collection techniques. A purposive sample of healthcare educators participated in one-to-one semi-standardized interviews and was observed in a teaching situation for demonstration of self-identified behaviors they believed actualized their image. Thematic analysis of the data resulted in five categories: coming to the role, perceptions held by subjects regarding image, people who may have influenced the image, behaviors that actualized the image and self-perceived …

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Drug-Loaded Tumor Cells For Lung Cancer Chemotherapy., Jun Shao Jan 1997

Drug-Loaded Tumor Cells For Lung Cancer Chemotherapy., Jun Shao

Graduate Theses, Dissertations, and Problem Reports (ETD)

Objective. To develop a targeting delivery system for lung cancer prevention and treatment using tumor cells as the drug carrier. Methods. Doxorubicin has been loaded into B16-F10 murine melanoma. This drug-loaded tumor cell system (DLTC) has been characterized, and its anticancer activity evaluated on C57BL/6J mice bearing pulmonary B16-F10 melanoma. Results. Up to 96 {dollar}\\rm\\mu g{dollar} of doxorubicin could be loaded into {dollar}10\\sp6{dollar} cells. The release of drug from the DLTC was both cell concentration and temperature dependent. Over a six-month storage at {dollar}\\rm 4\\sp\\circ C,{dollar} there was a 25% loss of intracellular drug and 8% loss of the carrier …

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Studies On Molecular Mechanisms Of The Immunotoxic Effects Of Propanil On T Cell Development And Cytokine Production., Wei Zhao Jan 1996

Studies On Molecular Mechanisms Of The Immunotoxic Effects Of Propanil On T Cell Development And Cytokine Production., Wei Zhao

Graduate Theses, Dissertations, and Problem Reports (ETD)

Propanil is a post-emergent herbicide which has been extensively used for control of weeds in rice and wheat field. Acute exposure to propanil central nervous system depression, loss of a righting reflex, and cyanosis. The immunotoxic effects of propanil on animals include reduction of thymus weight and cellularity with increase of spleen weight and cellularity, inhibition of humoral and cell-mediated immune response and alteration NK cell activity and macrophage cytotoxicity. The overall goal of this project is to investigate the mechanism and recovery of propanil induced thymic atrophy and the effect of propanil on T cell cytokine production. Using cell …

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Katelyn's Emergent Literacy Story: A Case Study And Consolidated Literature Review Of The Development Of Literacy From Birth To Three Years., Sherrie Kimberly Wampler Jan 1996

Katelyn's Emergent Literacy Story: A Case Study And Consolidated Literature Review Of The Development Of Literacy From Birth To Three Years., Sherrie Kimberly Wampler

Graduate Theses, Dissertations, and Problem Reports (ETD)

By definition, the study of emergent literacy must address the literacy development of children from "birth" to "conventional literacy." In actuality, studies of the literacy development of children between the ages of 2 and 4 have become common, while studies regarding literacy development of 1-year-olds is extremely limited and studies beginning at birth even fewer. Through this study, data regarding the language, reading, and writing behaviors of children from birth to three years is identified, consolidated, and confirmed. Two research questions guided this study: (1) What are the emergent literacy behaviors of a child from birth to three years? (2) …

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A Cellular Model For Automatic Transport Systems., Yang Cai Jan 1996

A Cellular Model For Automatic Transport Systems., Yang Cai

Graduate Theses, Dissertations, and Problem Reports (ETD)

In this study, the Transit Automata (TA) model, a Cellular Automata (CA) based spatial model, has been developed. It includes a set of cells, states, rules, events, and a system clock. In contrast to CA, a TA model fragments the problem space along restricted routes. All cells on the routes are treated as equal and controlled by rules. Like CA models, an initial configuration of a TA model can be embedded and can be dynamically changed during the runtime. Furthermore, user-controlled events and stochastic events are used to trigger the discrete events of the model. A TA model is a …

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Intensity Of Systemic Alarms In Content-Specific Fear Conditioning Comparing 20 Percent Vs. 13 Percent Carbon Dioxide-Enriched Air As Ucss., John Patrick Forsyth Jan 1996

Intensity Of Systemic Alarms In Content-Specific Fear Conditioning Comparing 20 Percent Vs. 13 Percent Carbon Dioxide-Enriched Air As Ucss., John Patrick Forsyth

Graduate Theses, Dissertations, and Problem Reports (ETD)

To examine the relation between the intensity of systemic bodily events and content-specific fear conditioning to stimuli that are fear-relevant or prepared for such associations, the present study involved a direct comparison between the conditioning effects produced by 20% and 13% CO{dollar}\\sb2{dollar}-enriched air (UCSs) to three CS types: external fear-relevant (snake moving toward viewer), internal fear-irrelevant (human heart beating arrhythmically), or neutral control (flowers swaying in the wind). Sex-balanced groups of undergraduate participants (N = 96) were assigned to one of the three CSs, and within each CS, to either 20% or 13% CO{dollar}\\sb2{dollar}-enriched air (UCSs). A variety of autonomic …

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Development And Assessment Of A Standard Dissolution Methodology For Protein-Based Injectable Suspensions., Sunil Prabhu Jan 1996

Development And Assessment Of A Standard Dissolution Methodology For Protein-Based Injectable Suspensions., Sunil Prabhu

Graduate Theses, Dissertations, and Problem Reports (ETD)

To date, no standard dissolution methodology is recognized in the official compendia for protein-based injectable suspensions. Development of a sensitive dissolution method would have utility as an in vitro quality control tool and an indicator of associated in vivo product performance. Using the spin-filter as the dissolution device of choice, the objective of these studies was to develop a standard dissolution methodology for protein-based suspensions. Secondarily, the objective was to elucidate the steps which critically influence ion-complexed protein dissolution, and assess the magnitude of their effect. In Phase I of dissolution methodology development, studies of the device hydrodynamics concluded that …

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Analysis Of Regulatory Regions Within The First Intron Of The Estrogen-Inducible Chicken Very Low Density Apolipoprotein Ii Gene., Franklin David Shuler Jan 1996

Analysis Of Regulatory Regions Within The First Intron Of The Estrogen-Inducible Chicken Very Low Density Apolipoprotein Ii Gene., Franklin David Shuler

Graduate Theses, Dissertations, and Problem Reports (ETD)

During periods of egg laying in the chicken, when circulating levels of estrogen are increased, the liver-specific estrogen-dependent very low density apolipoprotein II (apoVLDL II) gene is expressed. Transcription is accompanied by estrogen-dependent, liver-specific changes in the chromatin conformation within and surrounding the gene. One of the regions that changes in conformation is in the promoter where the estrogen receptor along with multiple liver-specific and ubiquitous transcription factors interact in a cooperative manner to assemble a functional transcriptional initiation complex. However, the apoVLDL II gene is expressed at higher levels when the first intron is added to the promoter. Since …

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The Interrelation Of Gypsy Culture And School Culture: An Ethnography Study Of Interactions., Marina Izquierdo Carter Jan 1996

The Interrelation Of Gypsy Culture And School Culture: An Ethnography Study Of Interactions., Marina Izquierdo Carter

Graduate Theses, Dissertations, and Problem Reports (ETD)

The purposes of this study were to gain an understanding of the Gypsy culture and to discover the relationship, within the school domain, between the Gypsy children and the non-Gypsy teachers. The study was conducted in Malaga, Spain and lasted two and a half months. The research design for this study was qualitative. Data for this ethnographic research were gathered using three strategies: (1) participant observations, (2) interviews, (3) collecting school magazines. Three models of analysis for collected data were used: Domain analysis, Cultural Themes analysis, and Code Analysis. The Gypsy participants were part of the population of the Gypsy …

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