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Graduate Theses, Dissertations, and Problem Reports (ETD)

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Exposure To Perfluoroalkyl Chemicals And Its Relation To Serum Lipids, Serum Uric Acid, And Blood Pressure Levels In Children., Sarah Dee Geiger Jan 2012

Exposure To Perfluoroalkyl Chemicals And Its Relation To Serum Lipids, Serum Uric Acid, And Blood Pressure Levels In Children., Sarah Dee Geiger

Graduate Theses, Dissertations, and Problem Reports (ETD)

Introduction: PFCs are manmade chemicals that are very pervasive in the US. They have been found to be present in the blood of more than 98% of Americans and have a long half-life. Studies have shown that perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) have endocrine-disrupting properties and exposure is positively associated with serum lipids, serum uric acid, reproductive effects, low birth weight and cancers, among other negative health effects. Cardiovascular disease is a leading cause of death worldwide and risk factors include dyslipidemia, hyperuricemia, and hypertension. In this context, we examined the association between PFOA and PFOS and serum …


Effects Of D-Amphetamine On Delay Discounting With Different Response Requirements In Rats., Sally L. Huskinson Jan 2012

Effects Of D-Amphetamine On Delay Discounting With Different Response Requirements In Rats., Sally L. Huskinson

Graduate Theses, Dissertations, and Problem Reports (ETD)

Impulsive choice is often examined using a delay-discounting procedure where choice is between two reinforcers that differ in amount and delay. Impulsive choice can be influenced by many factors, including drug administration or the addition of a constant delay to the smaller, more immediate and larger, more delayed reinforcer. Little research has examined whether increasing the number of responses (fixed-ratio) or amount of time (fixed-interval) required to earn the smaller, more immediate and larger, more delayed reinforcers would decrease impulsive choice. The current experiments used a modified Evenden and Ryan (1996) procedure, and choice was examined under conditions where the …


Part I - Evaluating Effects Of Oligomer Formation On Cytochrome P450 2c9 Electron Transfer And Drug Metabolism, Part Ii - Utilizing Molecular Modeling Techniques To Study The Src-Interacting Proteins Actin Filament Associated Protein Of 110 Kda (Afap-110) And Cortactin., John Edward Jett Jan 2012

Part I - Evaluating Effects Of Oligomer Formation On Cytochrome P450 2c9 Electron Transfer And Drug Metabolism, Part Ii - Utilizing Molecular Modeling Techniques To Study The Src-Interacting Proteins Actin Filament Associated Protein Of 110 Kda (Afap-110) And Cortactin., John Edward Jett

Graduate Theses, Dissertations, and Problem Reports (ETD)

The dissertation has been divided into two parts to accurately reflect the two distinct areas of interest pursued during my matriculation in the School of Pharmacy at West Virginia University. In Part I, I discuss research probing the nature of electron transfer in the Cytochrome P450 family of proteins, a group of proteins well-known for their role in drug metabolism. In Part II, I focus on in silico and in vitro work developed in concert to probe protein structure and protein-protein interactions involved in actin filament reorganization and cellular motility. Part I. Cytochrome P450s (P450s) are an important class of …


Perceptions And Needs Of Agricultural Teachers On Classroom Diversity And Inclusion., Hari K. Vommi Jan 2012

Perceptions And Needs Of Agricultural Teachers On Classroom Diversity And Inclusion., Hari K. Vommi

Graduate Theses, Dissertations, and Problem Reports (ETD)

Classrooms in the United States are more diverse than ever. It is predicted that nearly half of the public education students in the United States will be other than White by 2019. Teachers should have positive attitudes towards classroom diversity and inclusion. They should be well prepared to teach effectively in a diverse classroom. The purpose of the study was to examine the perceptions, the perceived confidence levels, and the perceived needs of agricultural teachers on classroom diversity, inclusion and multicultural education. The study also assessed the willingness of the teachers to participate in college courses and/or professional trainings on …


Vascular Consequences Of Metabolic Syndrome Related Shifts In Cyclooxygenase Mediated Arachidonic Acid Metabolism, Adam G. Goodwill Dec 2011

Vascular Consequences Of Metabolic Syndrome Related Shifts In Cyclooxygenase Mediated Arachidonic Acid Metabolism, Adam G. Goodwill

Graduate Theses, Dissertations, and Problem Reports (ETD)

The metabolic syndrome is a multi-faceted disease state in which the initial pathology of obesity leads to the development of a cadre of comorbidities including, but not limited to, atherogenic dyslipidemia, a prothrombotic state, a proinflammatory state, a pro-oxidant state, hypertension and type II diabetes mellitus. The prevalence of obesity is drastically increasing both nationally and globally, indicating that understanding obesity related disease is more relevant now then ever before. The metabolic syndrome has been demonstrated to result in numerous deleterious consequences for afflicted individuals, not the least of which is peripheral vascular disease. While the study of peripheral vascular …


A Legislative Review Of U.S. Aquaculture: A State Analysis Relating To West Virginia, Ryan M. Benninger Dec 2011

A Legislative Review Of U.S. Aquaculture: A State Analysis Relating To West Virginia, Ryan M. Benninger

Graduate Theses, Dissertations, and Problem Reports (ETD)

This case study was designed and presented to allow a "reader-friendly" environment for aquaculture industry inquiry, specifically to pertain to West Virginia's recent surge in industry development. The sample for this thesis consisted of aquaculture producing states located within the continental U.S. The research design was qualitative descriptive that evaluated the legislative environments for each state aquaculture industry to ultimately pass recommendations for West Virginia. Of the states surveyed, it was found that 26 states enacted development acts for respective industries; 19 states were found to further develop with strategic plans. The greatest constraint discovered during this project was a …


Community Leadership Motivation: Factors That Influence Individuals Holding Leadership Roles In West Virginia Communities, Kelly Nix Dec 2011

Community Leadership Motivation: Factors That Influence Individuals Holding Leadership Roles In West Virginia Communities, Kelly Nix

Graduate Theses, Dissertations, and Problem Reports (ETD)

Community organizations play a vital role in a community's quality of life. Many organizations must count on volunteers to provide core services (Clary, Snyder & Ridge, 1992). Over the years, the volunteer rate has declined in West Virginia (Volunteering in America, 2010). The purpose of this study was to identify the factors that influence individuals holding volunteer leadership roles in communities. The population for the study was 577 members of the West Virginia Regional Planning and Development Council and the West Virginia Economic Development Council. The participants received a mailed survey that included 89 questions. Seventy of the 89 questions …


Characterization Of The Pharmacological Effects Of Digitoxin On Lung Epithelial Cells, Hosam Abdelmonaim Elbaz Dec 2011

Characterization Of The Pharmacological Effects Of Digitoxin On Lung Epithelial Cells, Hosam Abdelmonaim Elbaz

Graduate Theses, Dissertations, and Problem Reports (ETD)

Lung diseases (excluding cancer) account for 9% of all disease related mortalities while lung cancer accounts for 30% of cancer related mortalities. Therapeutic maneuvers, as surgery are usually unfeasible given the extreme vitality of the lung. Developing novel therapeutic alternatives for lung cancer requires a thorough understanding on the lung epithelial cell behavior following exposure to drugs. The goal of this dissertation was to examine how molecular and cellular characteristics, such as morphology and cell viability, of lung cancer cells will be altered upon exposure to digitoxin, a cardiac glycosides (CGs) and a digitoxin synthetic analog. CGs are a large …


Gis Assisted Problem Analysis Of Trail Erosion In Monongahela National Forest, Steven J. Storck Dec 2011

Gis Assisted Problem Analysis Of Trail Erosion In Monongahela National Forest, Steven J. Storck

Graduate Theses, Dissertations, and Problem Reports (ETD)

This research investigates the frequency and patterns of trail erosion on purposefully selected natural surface trails in Monongahela National Forest. Trail erosion is considered a non-self-limiting process which degrades trail beds making them unattractive, difficult to travel on, and has the potential to impact local streams with the introduction of silt. Recreation ecology research delineates factors which influence the rate of erosion on a trail into three broad categories: recreational use, environmental conditions, and managerial actions. This study tests the relationship of variables from each of these categories to the local patterns of erosion. Three sampling strategies are used to …


Land Use Pressure And Climate Impacts On Fire Regimes And Forest Regeneration In The Upper Tuul River Watershed, Mongolia, Thomas M. Saladyga Dec 2011

Land Use Pressure And Climate Impacts On Fire Regimes And Forest Regeneration In The Upper Tuul River Watershed, Mongolia, Thomas M. Saladyga

Graduate Theses, Dissertations, and Problem Reports (ETD)

This dissertation is composed of three chapters addressing the broad issues of land use, climate variability, and wildfire in central Mongolia. The first chapter describes a GIS model developed to map human impacts in the Upper Tuul River watershed. Forest establishment data were used to validate the application of the model with results indicating a high level of correspondence with a field assessment of human disturbance. Chapter two is a tree-ring based reconstruction of Palmer Drought Severity Index (PDSI) for the central Khan Khentii Mountains from 1675-2000. Changes in moisture availability were more frequent during the 20th century than any …


Behavior That Hurts: Theoretical Orientation, Terminology, And Diagnosis Of Self-Injury, Susannah C. Rowan Flamm Dec 2011

Behavior That Hurts: Theoretical Orientation, Terminology, And Diagnosis Of Self-Injury, Susannah C. Rowan Flamm

Graduate Theses, Dissertations, and Problem Reports (ETD)

Self-injurious behavior prevalence continues to rise in both adolescent and adult non-clinical populations and within adolescent and adult clinical populations. Despite a large volume of literature regarding the antecedents and functions of self-injury, exploration of clinician factors in regard to these clients is sparse. This study examined the associations among 346 doctoral level clinicians' theoretical orientations, preferred terminology to describe self-injurious behaviors, and preferred diagnoses for clients who engage in self-injury. Therapist variables such as age, years in practice, and gender were examined for their association with terminology and diagnostic preferences. Chi-square analyses were conducted for the two-way interactions and …


Avian Assemblages And Red-Eyed Vireo Nest Survival Within Mineland Forest, Jeremy Mizel Dec 2011

Avian Assemblages And Red-Eyed Vireo Nest Survival Within Mineland Forest, Jeremy Mizel

Graduate Theses, Dissertations, and Problem Reports (ETD)

Since the passage of the Surface Mining Control and Reclamation Act (SMCRA) in 1977, mined lands have generally been reclaimed to an environment characterized by severely compacted minesoils, a growth medium comprised largely of unweathered materials, and a predominance of aggressive groundcovers that inhibit native species colonization. Under these conditions, succession is arrested. Within landscapes that are fragmented by traditionally reclaimed surface mines, forest patches are smaller and forest cover on the landscape scale is reduced. As a result, forest songbirds that require large, continuous blocks of forest are negatively affected.;Some pre-SMCRA abandoned minelands contain areas of uncompacted minesoils on …


Issues In The Care Of Farm Animals: Current History Of The Movement In Selected States, Jennifer N. Dunn Dec 2011

Issues In The Care Of Farm Animals: Current History Of The Movement In Selected States, Jennifer N. Dunn

Graduate Theses, Dissertations, and Problem Reports (ETD)

Many animal care practices commonly accepted as a regular part of the agricultural industry are being questioned by organizations advocating for the care of farm and companion animals. The use of gestation crates for pregnant sows, veal crates for veal calves, and battery cages for egg-laying hens are being banned in some states in the United States. While appearing to be a modern phenomenon, animal rights/animal welfare issues actually can be found throughout history. The purpose of the study was to trace the history of the care of farm and companion animals movement in the United States. This included the …


Response Elimination, Reinforcement Rate And Resurgence Of Operant Behavior, Carlos Renato Xavier Cancado Dec 2011

Response Elimination, Reinforcement Rate And Resurgence Of Operant Behavior, Carlos Renato Xavier Cancado

Graduate Theses, Dissertations, and Problem Reports (ETD)

The effects of reinforcement rates of alternative responding on resurgence were studied in six experiments with pigeons. In Experiment 1A, key pecking was maintained on a multiple variable-interval (VI) VI schedule during the first, Training, phase. In the second, Response-Elimination, phase, variable differential-reinforcement-of-other-behavior (DRO) schedules were in effect in each component and reinforcement rates were equal and then, higher in one (rich) component, and lower in the other (lean), than in the Training phase. In the third, Resurgence, phase, reinforcers were discontinued and more resurgence occurred in the lean than in the rich component. Differences in Training-phase response rates between …


Bioelectrical Impedance Analysis Methods For Prediction Of Brook Trout Salvelinus Fontinalis Percent Dry Weight, Andrew William Hafs Dec 2011

Bioelectrical Impedance Analysis Methods For Prediction Of Brook Trout Salvelinus Fontinalis Percent Dry Weight, Andrew William Hafs

Graduate Theses, Dissertations, and Problem Reports (ETD)

Reliable fish condition estimates are valued by fisheries ecologists and managers. Fish condition is used as an indicator of ecosystem health or to assess the population status for a species of interest. In aquaculture, proximate composition estimates are often wanted because of their relationship to fillet quality. Past researchers have used bioelectrical impedance analysis (BIA) to provide nonlethal mass based estimates of proximate composition for fish. Percent dry weight (PDW) of a fish is highly correlated to proximate composition values and energy density, therefore reliable predictions of PDW would eliminate the need for costly and laboratory analyses lethal to the …


Repression Of Phlpp By Mir-190 Contributes To Arsenic-Induced Akt Activation And Carcinogenesis, Kevin John Beezhold Dec 2011

Repression Of Phlpp By Mir-190 Contributes To Arsenic-Induced Akt Activation And Carcinogenesis, Kevin John Beezhold

Graduate Theses, Dissertations, and Problem Reports (ETD)

Arsenic is a well-studied human carcinogen. The mechanism by which arsenic induces cancer, however, is not fully understood. It is known that as a general stress inducer, arsenic can activate kinases, such as mitogen-activated protein kinases, leading to over activation of transcription factors. These transcription factors, including AP-1, NF-kB and Myc, are known to regulate the expression of early response genes, and likely to regulate miRNAs. The expression of miRNAs is often altered in cancer and other proliferative disorders. It is highly probable that miRNAs whose expressions are altered by arsenic will play a significant role in carcinogenesis. To test …


Efficient Design Of Biological Experiments For Dose-Response Modeling In Nanomaterial Toxicology Studies, Kai Wang Dec 2011

Efficient Design Of Biological Experiments For Dose-Response Modeling In Nanomaterial Toxicology Studies, Kai Wang

Graduate Theses, Dissertations, and Problem Reports (ETD)

This thesis is concerned with developing two-stage Bayesian optimum design procedure in nanotoxicology with simulation experiments. The proposed design method adopts suitable nonlinear dose response curve and non-constant variance model in experimental modeling, which more adequately represents the desirable properties of bioassay-experiment. A multiple objective genetic algorithm were used to select best set of non-dominated experiments on Pareto front. The proposed approach has been shown to provide better design than traditional experiment method in terms of D-optimum design and A-optimum design.


Nesting Biology Of Osmia Cornifrons: Implications For Population Management, Matthew Mckinney Dec 2011

Nesting Biology Of Osmia Cornifrons: Implications For Population Management, Matthew Mckinney

Graduate Theses, Dissertations, and Problem Reports (ETD)

The Japanese hornfaced bee, Osmia cornifrons (Hymenoptera: Megachilidae) is a palearctic mason bee managed for the pollination of early season fruit crops such as apple and blueberry. Since its adoption as a managed pollinator in Japan during the 1940s, a large body of literature has amassed with the goal of enhancing O. cornifrons management practices. This research makes important contributions to that literature in two ways. First, the research describes the in-nest relationship of O. cornifrons and the cleptoparasitic mite pest Chaetodactylus krombeini. Distribution of male and female O. cornifrons and of C. krombeini was determined using linear and non-linear …


Characterization Of M-Cadherin's Role In Regulating Apoptosis And Myogenic Differentiation Of Myoblasts By Interacting With Key Components Of Canonical Wnt Signaling, Yan Wang Dec 2011

Characterization Of M-Cadherin's Role In Regulating Apoptosis And Myogenic Differentiation Of Myoblasts By Interacting With Key Components Of Canonical Wnt Signaling, Yan Wang

Graduate Theses, Dissertations, and Problem Reports (ETD)

Activation, proliferation, and differentiation of satellite cells are the basic means for adult muscle regeneration. Apoptosis is concurrent to differentiation of satellite cells and dysregulated apoptosis contributes to the occurrence and progression of certain muscular dystrophies. This study investigated the role of M-cadherin-mediated signaling in regulating apoptosis versus survival of myoblasts during the process of myogenic differentiation. Inhibition of M-cadherin expression by RNAi (RNA interference) in confluent C2C12 myoblasts sensitized the cells to mitochondria-associated intrinsic apoptosis induced by either cell confluence or serum starvation. Manipulation of M-cadherin signaling regulated the Glycogen Synthase Kinase-3beta (GSK-3beta) activity via phosphoinositide-3 kinase (PI3K)/Akt pathway. …


Effects Of Delay Order And D-Amphetamine On Delay Discounting In Rats, Shana R. Bailey Dec 2011

Effects Of Delay Order And D-Amphetamine On Delay Discounting In Rats, Shana R. Bailey

Graduate Theses, Dissertations, and Problem Reports (ETD)

Impulsive choice is defined as choice for a smaller, more immediate reinforcer over a larger, more delayed reinforcer, whereas self-controlled choice is defined as choice for a larger, more delayed reinforcer over a smaller, more immediate reinforcer. Determinants of impulsive and self-controlled choices may be studied by employing delay-discounting procedures. When using a discrete-trials delay-discounting procedure, a difference in delay discounting as a function of order of presentation of delays to larger-reinforcer delivery was reported by one previous study, whereas another study reported no differences. In both studies, subjects had a history of exposure to both ascending and descending order …


The Effects Of Genetic Strain And Finisher Diet Non-Phytate Phosphorus Level On Performance, Lysine Degradation And Litter Composition Of Large Tom Turkeys, Brittany Nicholle Swiger Aug 2011

The Effects Of Genetic Strain And Finisher Diet Non-Phytate Phosphorus Level On Performance, Lysine Degradation And Litter Composition Of Large Tom Turkeys, Brittany Nicholle Swiger

Graduate Theses, Dissertations, and Problem Reports (ETD)

Successful commercial turkey production requires proper genetic strain selection to optimize live performance and profit. In addition, sustainable practices relative to manure disposal are essential due to perceptions that land application of poultry manure is a primary contributor to watershed eutrophication. The objective of our research was to assess genetic strain and finisher diet non-phytate phosphorus (nPP) level effects on large tom performance and litter composition using a research facility that mimics commercial production. Experiments were 2x2 factorial designs utilizing 2 strains (Nicholas and Hybrid) and 2 levels of dietary nPP (normal and low) in finishing diets. Two experiments of …


Encoding Of Temporal Sound Features In The Rodent Superior Paraolivary Nucleus, Richard A. Felix Ii Aug 2011

Encoding Of Temporal Sound Features In The Rodent Superior Paraolivary Nucleus, Richard A. Felix Ii

Graduate Theses, Dissertations, and Problem Reports (ETD)

The superior paraolivary nucleus (SPON) is a prominent cell group in the mammalian brainstem. SPON neurons are part of a monaural circuit that encodes temporal sound features in the ascending auditory pathway. Such attributes of acoustic signals are critical for speech perception in humans and likely equally as important in animal communication. While basic properties of SPON neurons have been characterized in some detail, a comprehensive examination of mechanisms that underlie their ability to precisely represent temporal information is lacking. Furthermore, little is known of how the SPON impacts its primary target, the inferior colliculus. Combinations of electrophysiological, pharmacological and …


Fragipan Influence On Hydropedological Properties Of Benchmark Soilscapes In West Virginia, John F. Beck Aug 2011

Fragipan Influence On Hydropedological Properties Of Benchmark Soilscapes In West Virginia, John F. Beck

Graduate Theses, Dissertations, and Problem Reports (ETD)

Soil wetness and the interactions between soil and water influence the potential uses of soil and must be considered when making decisions regarding soil use and management. The strategic placement of hydrologic monitoring instrumentation on a benchmark soilscape is critical toward providing the users of soil information with reliable predictability of water movement at the soil-water interface.;A hydropedologically significant study site that satisfies the benchmark soilscape criteria as defined by the Natural Resources Conservation Service (NRCS) was selected for this research. Because of the high cost of performing investigations and research, benchmark soils are targeted and the information gleaned from …


The Association Of Markers Of Endothelial Dysfunction And Incident Diabetes Mellitus, Hypertension, Chronic Kidney Disease And Cardiovascular Mortality, Loretta Rena Cain Aug 2011

The Association Of Markers Of Endothelial Dysfunction And Incident Diabetes Mellitus, Hypertension, Chronic Kidney Disease And Cardiovascular Mortality, Loretta Rena Cain

Graduate Theses, Dissertations, and Problem Reports (ETD)

In recent years several mechanistic animal studies have proposed new insights, including the role of endothelial dysfunction, in the pathogenesis of common cardiometabolic disorders such as diabetes mellitus, hypertension, chronic kidney disease (CKD) and cardiovascular disease (CVD). However, few studies in humans have followed up these emerging leads from animal models. Because traditional risk factors have been shown not to completely explain all the observed risk of cardiometabolic outcomes in the general population, there is a need to examine novel mechanisms such as endothelial dysfunction in population-based studies, so as to identify new ways of preventing and/or treating these diseases. …


Effect Of Intravenous Treatment With The Oxytocin Antagonist Atosiban On Circulating Progesterone In The Ewe, Todd M. Ramboldt Aug 2011

Effect Of Intravenous Treatment With The Oxytocin Antagonist Atosiban On Circulating Progesterone In The Ewe, Todd M. Ramboldt

Graduate Theses, Dissertations, and Problem Reports (ETD)

Effects of oxytocin on the ovine corpus luteum have been controversial for a number of years. The present study investigated the effects of atosiban, a combined oxytocin and vasopressin 1A antagonist, administered systemically to ewes on post estrus day 8 to 10. Atosiban was given in four bolus intravenous injections at 0, 60, 120 and 180 minutes with blood sampling every 15 minutes from -60 through 480 minutes. Concentrations of serum progesterone ng/ml were measured via radioimmunoassay. A log10 transformation of progesterone values was conducted to account for the heterogeneity of variance of the values. During the treatment interval (0 …


The Effect Of Conjugated Linoleic Acid (Cla) On Feed Efficiency And Carcass Composition In Barrows, Natasha R. Winslow Aug 2011

The Effect Of Conjugated Linoleic Acid (Cla) On Feed Efficiency And Carcass Composition In Barrows, Natasha R. Winslow

Graduate Theses, Dissertations, and Problem Reports (ETD)

The purpose of this study was to determine if conjugated linoleic acid (CLA) would have an effect on feeding efficiency and carcass composition of 20 finishing barrows obtained from the West Virginia University Animal Science Farm. A posttest experimental design was used to obtain data for the study. The barrows were matched for weight and placed two in a pen. The pens were randomly assigned to a diet consisting of either a 1% CLA oil or 1% soybean oil. The six week study found that weight gain, average daily feed intake, muscle lipids, loin eye area, and color were not …


Characterizing Textural Attributes Of Rainbow Trout, Oncorhynchus Mykiss, Fillets As Affected By Age, Sterility, And Storage Regimen, Aunchalee Aussanasuwannakul Aug 2011

Characterizing Textural Attributes Of Rainbow Trout, Oncorhynchus Mykiss, Fillets As Affected By Age, Sterility, And Storage Regimen, Aunchalee Aussanasuwannakul

Graduate Theses, Dissertations, and Problem Reports (ETD)

Trout fillets, subjected to refrigeration (4°C; 3 or 7 d) by frozen storage (-25°C; 0 or 30 d) combinations, were cooked; texture, determined by a novel, variable-blade (VB) attachment, was compared with a widely-used Allo-Kramer shear (AK) attachment to determined its sensitivity in detecting variation in fillet texture. Instrumental texture was related to sensory measurements to determine attachments' accuracy in assessing cooked fillet texture. Weight of raw fillets decreased after 30-d frozen storage. Fillet weight further decreased after cooking. Moisture content decreased while fat content remained constant. The AK attachment detected differences in energy of shear, which decreased after 30-d …


Characterization And Genetic Manipulation Of Ergot Pathway Inefficiency In Fungi, Prashanthi Mulinti Aug 2011

Characterization And Genetic Manipulation Of Ergot Pathway Inefficiency In Fungi, Prashanthi Mulinti

Graduate Theses, Dissertations, and Problem Reports (ETD)

Ergot alkaloids are mycotoxins that negatively affect humans and animals but also have useful pharmaceutical properties. Ergot alkaloids have been extensively studied in Claviceps purpurea, and also have been reported in other fungi, such as certain Penicillium spp., Aspergillus fumigatus, and several Neotyphodium spp. that are endophytes of grasses. There is a high degree of variation in the production of ergot alkaloids within an individual species and among producers from different taxa, which means different fungi accumulate different profiles of ergot alkaloids rather than a single pathway end product. These varied profiles result, in part, from inefficiency in the pathway …


Effects Of Age And Early Life Ozone Exposure On The Developmental Dynamics Of Afferent Airway Neurons In Postnatal Rats, Leor C. Zellner Aug 2011

Effects Of Age And Early Life Ozone Exposure On The Developmental Dynamics Of Afferent Airway Neurons In Postnatal Rats, Leor C. Zellner

Graduate Theses, Dissertations, and Problem Reports (ETD)

The environmental irritant ozone (O3) plays a role in airway inflammation and is known to cause airway hyperresponisiveness especially in susceptible populations such as asthmatics and young children. O3 exposure increases nerve growth fact (NGF) mRNA and protein levels in the airways, and alters the expression of substance P (SP) in nodose and jugular afferent airway neurons and in sensory nerve fibers in the airways. The growth and development of vagal afferent neurons is in part regulated by NGF, and because these sensory neurons continue to develop throughout postnatal life O3 exposures during this period may adversely affect their development. …


Relationships Among Fish Assemblages, Hydroperiods, Drought, And American Alligators Within Palustrine Wetlands Of The Blackjack Peninsula, Aransas National Wildlife Refuge, Texas, Darrin M. Welchert Aug 2011

Relationships Among Fish Assemblages, Hydroperiods, Drought, And American Alligators Within Palustrine Wetlands Of The Blackjack Peninsula, Aransas National Wildlife Refuge, Texas, Darrin M. Welchert

Graduate Theses, Dissertations, and Problem Reports (ETD)

The following thesis contains two chapters. In Chapter 1, I have reviewed and summarized literature pertaining to fishes and habitats of palustrine wetlands, the influence of hydroperiods on wetland fishes, the impacts of drought on wetland fishes, the importance of American alligators as ecological engineers of fish habitats within wetlands, and fish sampling within wetland habitats. Chapter 2 is a manuscript representing my thesis research. In this study, primary focus is placed on how fish diversity and how fish abundances of palustrine wetlands are influenced by drought conditions within the Blackjack Peninsula of the Aransas National Wildlife Refuge in southwestern …