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Full-Text Articles in Entire DC Network
A Novel Approach To Competency-Based Education For Pediatric Nurse Practitioners: Bringing Clarity To Competencies, Kristina L. Banks, Carol L. Savrin
A Novel Approach To Competency-Based Education For Pediatric Nurse Practitioners: Bringing Clarity To Competencies, Kristina L. Banks, Carol L. Savrin
Faculty Scholarship
Introduction: Guidance for Pediatric Nurse Practitioner (PNP) competency-based education (CBE) is provided by the National Organization of Nurse Practitioner Faculties (NONPF) and the American Association of Colleges of Nursing (AACN) The Essentials: Core Competencies for Professional Nursing Education (“Essentials”). The 2021 AACN Essentials update prompted a significant shift from traditional to (CBE)for Nurse Practitioner (NP) faculty. NONPF has responded, updating its NP Role Core Competencies and domains to be congruent with the AACN 2021 Essentials, but NONPF's population-specific competencies remain unchanged since 2013. Methods: Two PNP faculty conducted a multistep crosswalk between the NONPF 2013 population-based competencies for Primary and …
Movement Disorders In Relapsing And Progressive Ms: A Comprehensive Prospective Evaluation Of A Large Real-Life Cohort, Hannah Kelly, Rongyi Sun, Mohamed Elkasaby, Alexander Wang, Hesham Abboud
Movement Disorders In Relapsing And Progressive Ms: A Comprehensive Prospective Evaluation Of A Large Real-Life Cohort, Hannah Kelly, Rongyi Sun, Mohamed Elkasaby, Alexander Wang, Hesham Abboud
Faculty Scholarship
Background: Recent studies suggest that movement disorders are common in early MS. However, the frequency and clinical characteristics of movement disorders at all stages of MS remain unknown. Objectives: To evaluate the frequency, clinical characteristics, and anatomical generators of movement disorders in relapsing and progressive MS. Methods: We conducted a prospective study of adult MS patients from 2016 to 2022 at a neuroimmunology clinic. Patients were evaluated for demyelination-related movement disorders via a survey and focused examination. We classified movement disorders based on phenomenology and identified anatomic correlates according to lesion locations and relation to relapses. Findings were compared between …
Examining The Effects Of Mental Health And Parent–Youth Relationship On The Associations Between Childhood Violence Exposure And Adolescent Dating Violence Perpetration, Laura A. Voith
Faculty Scholarship
Background/objectives: Adolescent dating violence (ADV) is a serious public health concern affecting youth worldwide. Potential risk factors of ADV include child maltreatment (CM) and intimate partner violence exposure (eIPV), though existing research on ADV perpetration specifically is inconsistent. There is limited research on co-occurring eIPV and CM, despite co-occurrence in 30–60% of homes where there is one. This study aims to address these gaps by testing the impact of childhood violence exposure on ADV perpetration and assessing two potential, theory-informed mitigating factors—mental health and parent–youth relationship. Methods: This study utilizes moderated-mediation structural equation modeling with longitudinal data from a sample …
Cgas/Sting-Independent Induction Of Type I Interferon By Inhibitors Of The Histone Methylase Kdm5b, Monica M. Montano, I. Ju Yeh, Wannarasmi Ketchart
Cgas/Sting-Independent Induction Of Type I Interferon By Inhibitors Of The Histone Methylase Kdm5b, Monica M. Montano, I. Ju Yeh, Wannarasmi Ketchart
Faculty Scholarship
Studies support the role of hexamethylene bis-acetamide [HMBA] induced protein 1 (HEXIM1) as a tumor suppressor. We previously reported that the histone demethylase, KDM5B, inhibits the expression of HEXIM1, and KDM5B inhibitors (KDM5Bi) upregulate HEXIM1 expression. As a consequence, KDM5Bi inhibited cell proliferation, induced differentiation, potentiated sensitivity to cancer chemotherapy, and inhibited breast tumor metastasis. HEXIM1 is crucial for the regulation of triple-negative breast cancer (TNBC) phenotype by KDM5Bi. Type I Interferon (IFN-I) employs the immune system in the tumor microenvironment to restrict tumor growth. Moreover, therapeutic approaches (including mainstay chemotherapy) engage IFN-I signaling. We report herein that HEXIM1 and …
Surface-Electromyography Characteristics Of Clonic Seizures With No Scalp-Eeg Correlate: A Comparative Analysis With Tremors, Akshaya R. Sivaji, Shwetank Singh, Zachary Scicchitano, Roohi Katyal, Neel Fotedar
Surface-Electromyography Characteristics Of Clonic Seizures With No Scalp-Eeg Correlate: A Comparative Analysis With Tremors, Akshaya R. Sivaji, Shwetank Singh, Zachary Scicchitano, Roohi Katyal, Neel Fotedar
Faculty Scholarship
Introduction: Clonic seizures are characterized by twitching movements at a frequency of 0.2–5 Hz. The clonic “twitch” is produced by a brief synchronized contraction of agonist and antagonist muscles, followed by a synchronized silent period. In this study, we aimed to compare the surface-electromyography (sEMG) characteristics of scalp-EEG negative clonic seizures with those of nonepileptic movements like tremors that can resemble clonic seizures. Methods: We retrospectively identified patients who were diagnosed with scalp-EEG negative clonic seizures or tremors. We only included patients (n = 6) who were monitored simultaneously with video-EEG and sEMG electrodes. sEMG was placed on agonist and …
The Diverse Roles Of Complex Glycans In Synapse Development And Function, Peng Zhang
The Diverse Roles Of Complex Glycans In Synapse Development And Function, Peng Zhang
Faculty Scholarship
Protein glycosylation is a critical post-translational modification that mediates a myriad of biological functions, including neuronal development in the brain. Stages of neuronal development include neurogenesis, neuronal migration, axonal guidance, synapse formation, and activity-dependent synaptic remodeling and plasticity. Among these, synapse formation and plasticity are essential to establish and maintain neuronal circuits for proper brain function. Yet, the physiological role of glycans at synapses remains poorly understood. This is especially true for complex glycans, known for decades to be present on the cell surface or extracellular matrix, including the microenvironment around synapses. In this review, we highlight recent examples of …
Apolipoprotein E (Apoe) And Alzheimer's Disease Risk In A Ugandan Population: A Pilot Case-Control Study, Martha Sajatovic
Apolipoprotein E (Apoe) And Alzheimer's Disease Risk In A Ugandan Population: A Pilot Case-Control Study, Martha Sajatovic
Faculty Scholarship
Alzheimer's disease (AD) is a neurodegenerative disorder that is characterized by cognitive decline and progressive functional impairment. The Apolipoprotein E (APOE) gene, particularly its ϵ2, ϵ3, and ϵ4 alleles, plays a crucial role in lipid metabolism, and has been implicated in AD pathogenesis. Although the APOE ϵ4 status is associated with an increased risk of AD, its impact varies across populations. This study investigated the prevalence of and association between APOE alleles and AD risk in a Ugandan cohort. This case-control study was conducted in Uganda, and included 87 participants (45 patients with AD and 42 healthy controls). Cognitive assessment …
Congress Of Neurological Surgeons Systematic Review And Evidence-Based Guidelines For The Role Of Imaging In Newly Diagnosed Who Grade Ii Diffuse Glioma In Adults: Update, Chaitra Badve, Abraham Nirappel
Congress Of Neurological Surgeons Systematic Review And Evidence-Based Guidelines For The Role Of Imaging In Newly Diagnosed Who Grade Ii Diffuse Glioma In Adults: Update, Chaitra Badve, Abraham Nirappel
Faculty Scholarship
Target population: Adult patients with suspected or histologically proven WHO Grade II diffuse glioma. Question 1: In adult patients with suspected or histologically proven WHO Grade II diffuse glioma, do advanced MRI techniques using magnetic resonance spectroscopy, perfusion weighted imaging or diffusion weighted imaging provide superior assessment of tumor grade, margins, progression, treatment-related effects, and prognosis compared to standard neuroimaging? Recommendation: Level II: The use of diffusion imaging and dynamic susceptibility contrast (DSC), dynamic contrast enhancement (DCE) and arterial spin labeling (ASL) sequences are suggested to differentiate WHO Grade II diffuse glioma from higher grade gliomas when this is not …
Tnf-Α-Driven Changes In Polarized Egf Receptor Trafficking Facilitate Phosphatidylinositol 3-Kinase/Protein Kinase B Signaling From The Apical Surface Of Mdck Epithelial Cells, Syntyche Ngalula, Cathleen R. Carlin
Tnf-Α-Driven Changes In Polarized Egf Receptor Trafficking Facilitate Phosphatidylinositol 3-Kinase/Protein Kinase B Signaling From The Apical Surface Of Mdck Epithelial Cells, Syntyche Ngalula, Cathleen R. Carlin
Faculty Scholarship
This manuscript describes a novel unconventional secretory pathway that facilitates EGF receptor (EGFR) signaling from apical membranes in polarized epithelial cells responding to immune cell mediators. Epithelial tissues provide a physical barrier between our bodies and the external environment and share an intimate relationship with circulating and local immune cells. Our studies describe an unexpected connection between the proinflammatory cytokine tumor necrosis factor-alpha (TNF-α) and EGFR typically localized to basolateral membranes in polarized epithelial cells. These two molecules sit atop complex biological networks with a long history of shared investigative interest from the vantage point of signaling pathway interactions. We …
On Metric Choice In Dimension Reduction For Fréchet Regression, Abdul Nasah Soale, Congli Ma, Siyu Chen
On Metric Choice In Dimension Reduction For Fréchet Regression, Abdul Nasah Soale, Congli Ma, Siyu Chen
Faculty Scholarship
Fréchet regression is becoming a mainstay in modern data analysis for analysing non-traditional data types belonging to general metric spaces. This novel regression method is especially useful in the analysis of complex health data such as continuous monitoring and imaging data. Fréchet regression utilises the pairwise distances between the random objects, which makes the choice of metric crucial in the estimation. In this paper, existing dimension reduction methods for Fréchet regression are reviewed, and the effect of metric choice on the estimation of the dimension reduction subspace is explored for the regression between random responses and Euclidean predictors. An extensive …
Predicting Sorption Of Diverse Organic Compounds In Soil-Water Systems: Meta-Analysis, Machine Learning Modeling, And Global Soil Mapping, Jiachun Sun, Kai Zhang, Huichun Zhang
Predicting Sorption Of Diverse Organic Compounds In Soil-Water Systems: Meta-Analysis, Machine Learning Modeling, And Global Soil Mapping, Jiachun Sun, Kai Zhang, Huichun Zhang
Faculty Scholarship
In recent decades, the environmental detection of various organic compounds (OCs) has highlighted the limitations of conventional soil-water sorption models, which simplify complex experimental conditions and often overlook OCs with polyfunctional and ionizable structures. To address these shortcomings, we compiled a comprehensive soil-water sorption dataset encompassing 20,945 data points for 419 OCs with various functional groups and 1037 different soils. Meta-analysis of the dataset revealed the trends of soil sorption associated with OC substructures, soil properties, and solution conditions. Machine learning models employing the XGBoost algorithm, in conjunction with MACCS fingerprints and experimental conditions, were developed to cover the entire …
The Rising Returns To R&D: Ideas Are Not Getting Harder To Find, Yoshiki Ando, James Bessen, Xiupeng Wang
The Rising Returns To R&D: Ideas Are Not Getting Harder To Find, Yoshiki Ando, James Bessen, Xiupeng Wang
Faculty Scholarship
R&D investment has grown robustly, yet aggregate productivity growth has stagnated. Is this because “ideas are getting harder to find”? This paper uses micro-data from the US Census Bureau to explore the relationship between R&D and productivity in the manufacturing sector from 1976 to 2018. We find that both the elasticity of output (TFP) with respect to R&D and the marginal returns to R&D have risen sharply. Exploring factors affecting returns, we conclude that R&D obsolescence rates must have risen. Using a novel estimation approach, we find consistent evidence of sharply rising technological rivalry. These findings suggest that R&D has …
Breaking New Ground: Division Directly In Memory, M. Hassan Najafi, Mehran Shoushtari Moghadam
Breaking New Ground: Division Directly In Memory, M. Hassan Najafi, Mehran Shoushtari Moghadam
Faculty Scholarship
In-memory computing (IMC) has emerged as a promising paradigm for overcoming the limitations of traditional von Neumann architectures by reducing data movement and enhancing computational efficiency. Despite significant advancements in this area, implementing complex arithmetic operations, such as division, directly within memory has remained an elusive challenge. This paper introduces a pioneering technique for performing division operations directly in memory, representing the first successful integration of such functionality into the IMC framework. Our approach leverages an innovative circuit based on an unconventional model of computing–stochastic computing (SC). Our technique extends the computational capabilities of IMC systems and paves the way …
The Built Environment And Adverse Cardiovascular Events In Us Veterans With Cardiovascular Disease, Skanda Moorthy, Zhuo Chen, Tong Zhang, Sai Rahul Ponnana, Santosh Kumar Sirasapalli, Kanimozhi Shivanantham, Haitham Khraishah, Jean Eudes Dazard, Sadeer G. Al-Kindi, Salil V. Deo, Sanjay Rajagopalan
The Built Environment And Adverse Cardiovascular Events In Us Veterans With Cardiovascular Disease, Skanda Moorthy, Zhuo Chen, Tong Zhang, Sai Rahul Ponnana, Santosh Kumar Sirasapalli, Kanimozhi Shivanantham, Haitham Khraishah, Jean Eudes Dazard, Sadeer G. Al-Kindi, Salil V. Deo, Sanjay Rajagopalan
Faculty Scholarship
Question: Can AI-extracted interpretable built environment features predict major adverse cardiovascular events (MACE) in a national veteran population? Findings: In this cohort study of 770,990 U.S. veterans, seven built environment features were significantly associated with an increased risk of MACE. Two features, old/dilapidated buildings and visible wire, were associated with a decreased risk. Greenery was only linked to increased risk in higher social deprivation index quartiles. Meaning: Built environment features can serve as predictors of MACE, highlighting the potential role of neighborhood characteristics in cardiovascular risk stratification beyond traditional factors. Importance: The relationship between built environment features and major adverse …
Role Of Fluid-Structure Interactions In Mechanosensation During Hovering Flapping Flight, Menglong Lei, Chengyu Li
Role Of Fluid-Structure Interactions In Mechanosensation During Hovering Flapping Flight, Menglong Lei, Chengyu Li
Faculty Scholarship
Insect wings, known for their intricate structure and function, inherently deform during flapping motion. These deformations can be classified into chordwise cambering, spanwise bending, and root-to-tip twisting, arising from non-uniform venation distribution, aerodynamic loading, and wing inertia. Crucially, such deformations play a vital role in enhancing both aerodynamic performance and mechanosensory function. To investigate the complex interplay between wing structure, unsteady aerodynamics, and mechanosensation, we developed a fully coupled three-dimensional fluid-structure interaction (FSI) solver. This framework integrates an in-house Navier-Stokes equations solver for resolving the flow field with the open-source Vega FEM code to solve the solid structure dynamics. Our …
A Continuous-Heat-Flux Phase Change Model For Simulating Realistic Two-Phase Unsaturated Evaporation Processes, Thanh Hoang Phan, Cho Ning Huang, Chirag R. Kharangate
A Continuous-Heat-Flux Phase Change Model For Simulating Realistic Two-Phase Unsaturated Evaporation Processes, Thanh Hoang Phan, Cho Ning Huang, Chirag R. Kharangate
Faculty Scholarship
Accurately modeling liquid-vapor mass transfer rates is essential for optimizing cryogenic fluid management processes critical to advancing future space missions. This study introduces a continuous-heat-flux phase change model proposed to simulate conditions observed in realistic two-phase unsaturated evaporation phenomena. The mass transfer rate across the two-phase interface is calculated directly based on the local interfacial continuous heat flux on both liquid and vapor phases, effectively accounting for superheated, saturated, and subcooled liquid effects without requiring any empirical tuning parameters. Moreover, phase change occurs exclusively within interfacial cells, ensuring the sharp representation of deformed evaporating interfaces with high accuracy. The proposed …
Integrating Pre-Colonial Indigenous Australian Art Into Global Art History, Allison Bell, James Hutson
Integrating Pre-Colonial Indigenous Australian Art Into Global Art History, Allison Bell, James Hutson
Faculty Scholarship
Art history as a discipline remains dominated historically through Eurocentric frameworks, systematically marginalizing Indigenous artistic traditions, particularly pre-colonial Australian Aboriginal art. Despite evidence of profound antiquity and cultural richness, such art often occupies peripheral spaces in global narratives. This article addresses these limitations through an interdisciplinary approach, integrating precise archaeological dating methods—including radiocarbon analysis of mud wasp nests and uranium-series dating—with detailed art historical inquiry. Case studies focus specifically on landmark findings, such as the Gwion Gwion rock paintings in the Kimberley region (over 16,000 years old) and Australia’s oldest known in-situ kangaroo painting, dated approximately 17,300 years old. Comparative …
Eviction Sealing: A Lifeline In The Fight For Housing Justice, Allison Freedman
Eviction Sealing: A Lifeline In The Fight For Housing Justice, Allison Freedman
Faculty Scholarship
In January 2023, the White House released a Blueprint for a Renters Bill of Rights. The Blueprint called for immediate sealing of eviction case filings to reduce the likelihood that tenants would be locked out of future housing opportunities without the chance to defend themselves. Shortly thereafter, the Federal Trade Commission and the Consumer Financial Protection Bureau issued a request for public comment on how the use of eviction records and screening algorithms may affect tenant housing opportunities and drive discriminatory outcomes. The eviction crisis, its discriminatory effects, and the idea that sealing eviction records may provide a solution to …
Building Layered Defenses To Reduce Illegal Gun Violence, Samuel Kan
Building Layered Defenses To Reduce Illegal Gun Violence, Samuel Kan
Faculty Scholarship
This article examines a multifaceted approach to reducing illegal gun violence in the United States through the implementation of layered defense strategies. While acknowledging the constitutional protections afforded by the Second Amendment, the author argues that targeted legislative and community-based interventions can effectively reduce gun violence without infringing on lawful gun ownership rights. The analysis explores several key defensive measures, including extreme risk laws (risk protection orders), which allow for temporary firearm removal from individuals posing credible threats to themselves or others—a practice recently upheld by the Supreme Court in United States v. Rahimi. The article further examines the constitutional …
The Right To Grow Old, Jamal Greene
The Right To Grow Old, Jamal Greene
Faculty Scholarship
This chapter considers the status of a constitutional “right to grow old” under the US Constitution. Understood as a “positive” right – ensuring a certain minimum quality of life to people as they face the challenges of aging – such a right may seem unavailing given the austerity in respect to such rights that many lawyers associate with the US constitutional tradition. This chapter shows this view to be premature, at least. Unlike the kinds of positive rights overtly rejected in prior cases, such as rights to certain forms of social welfare or to racial equality, a right to grow …
Toward A Dynamic View Of Corporate Purpose, Dorothy S. Lund
Toward A Dynamic View Of Corporate Purpose, Dorothy S. Lund
Faculty Scholarship
Scholars debating the corporation’s role in society generally advance the view that there is only one desirable orientation for corporations and their management. Specifically, proponents of a stakeholder governance model contend that focusing management on a broad set of corporate constituents maximizes overall welfare, while advocates of a shareholder-centric directive counter that prioritizing shareholders creates social welfare by rendering the firm most profitable. This Article offers another view: It suggests that the welfare-maximizing purpose for corporations could change depending on external economic conditions, which both of these positions assume away. Specifically, shareholder primacy is likely to promote welfare in a …
Simulating Chill: Exploring The Cognitive And Therapeutic Potential Of Cold Vr Environments, Jessica Turner, Piper Hutson, James Hutson
Simulating Chill: Exploring The Cognitive And Therapeutic Potential Of Cold Vr Environments, Jessica Turner, Piper Hutson, James Hutson
Faculty Scholarship
This study investigates the cognitive and therapeutic potential of immersive virtual reality (VR) environments designed to simulate cold conditions. Through the engagement of participants through multisensory stimuli—including vivid visual representations of the Athabasca Glacier, auditory effects of icy winds, and corresponding haptic feedback—the research evaluates neurological and physiological responses associated with attention, emotional regulation, and stress modulation. Participants experienced virtual scenarios featuring icy winds and snow, activating specific neurological pathways involving the occipital lobe, primary visual cortex, superior colliculus, and insula, thus reinforcing sensory integration. Through predictive coding, the anterior insula and hypothalamus were engaged, prompting thermoregulatory simulations and subconscious …
1785 Parisian Salon Project: New Methods And Practical Innovations In Digital Heritage Reconstruction, James Hutson, Charles O'Brien, Wesley Wolfe, Kayla Kraff, Trent Olsen
1785 Parisian Salon Project: New Methods And Practical Innovations In Digital Heritage Reconstruction, James Hutson, Charles O'Brien, Wesley Wolfe, Kayla Kraff, Trent Olsen
Faculty Scholarship
The 1785 Salon Unreal Engine Reconstruction Project represents a significant advance in digital heritage and immersive art historical research by combining generative AI-based asset creation, modular user experience (UX) design, and historically informed workflows. During the Spring 2025 phase, the project achieved major milestones, including the successful development of a replicable pipeline for transforming 2D reference images into period-accurate 3D sculpture models using generative AI and digital sculpting tools. Simultaneously, a robust and adaptable Inspection System was engineered within Unreal Engine, offering granular interaction controls, bilingual (English/French) content integration, dynamic metadata display, and enhanced accessibility. These innovations collectively enabled historically …
Current Standards And Future Directions Of Duchenne Muscular Dystrophy Respiratory Care: The Ppmd Italy Meeting Report, Jane Black, David J. Birnkrant
Current Standards And Future Directions Of Duchenne Muscular Dystrophy Respiratory Care: The Ppmd Italy Meeting Report, Jane Black, David J. Birnkrant
Faculty Scholarship
Objective: This report summarizes key discussions from the meeting “Current Standards and Future Directions of Respiratory Assessment and Management of Duchenne Muscular Dystrophy (DMD),” organized by Parent Project Muscular Dystrophy (PPMD) Italy and the United States to address current challenges and opportunities in DMD respiratory care. Methods: The meeting brought together researchers, clinicians, and patient advocates who shared experiences, discussed advancements in DMD respiratory management, and identified areas of debate that require further research. Results: The speakers emphasized routine assessment of pulmonary function and of breathing during sleep to achieve timely diagnosis of respiratory complications. Therapeutic discussions focused on airway …
Pv Backsheets Survey Protocol: A Framework For Geo-Spatial Field Surveys For Bulk Material Characterization And Reliability Analysis Applied Across 41 Pv Systems, Raymond J. Wieser, Zelin Li, Xuanji Yu, Laura S. Bruckman
Pv Backsheets Survey Protocol: A Framework For Geo-Spatial Field Surveys For Bulk Material Characterization And Reliability Analysis Applied Across 41 Pv Systems, Raymond J. Wieser, Zelin Li, Xuanji Yu, Laura S. Bruckman
Faculty Scholarship
As widespread adoption of photovoltaic (PV) technologies continues, understanding the lifetime of modules is paramount to the viability of the industry as an environmentally conscious alternative to traditional energy generation. Although power degradation can affect the total energy production of a module over its lifetime, module safety failures necessitate the removal of a module leading to a loss of not only the particular asset, but the earning potential of the device. Therefore, it is critical to ensure that the components that provide essential safety functions for PV module operate for their entire rated lifetime. PV backsheets provide necessary electrical insulation …
Letter To The Fda Proposing Major Changes In The Us Clozapine Package Insert Supported By Clozapine Experts Worldwide. Part I A Review Of The Pharmacokinetic Literature And Proposed Changes, Martha Sajatovic
Faculty Scholarship
Purpose/Background: Clozapine was approved in the United States (US) using 1989 regulations and knowledge. After 30 years, many sections of the US package insert (PI) are outdated. Methods: We comprehensively reviewed the literature to propose PI updates. We present the information in 2 articles. In Part I, we focus on basic pharmacology based on 407 relevant articles. Part II focuses on clinical aspects and pharmacovigilance. Findings/Results: Based on more recent expectations of Food and Drug Administration regulations, we reviewed clozapine basic pharmacology including the following: 1) clearance, 2) pharmacokinetics and pharmacodynamics, and 3) monitoring tools. We identified 9 major problems …
Letter To The Fda Proposing Major Changes In The Us Clozapine Package Insert Supported By Clozapine Experts Worldwide. Part Ii A Review Of Fatal Outcomes In Us Pharmacovigilance Data And Proposed Changes, Martha Sajatovic
Faculty Scholarship
Purpose/Background: This is the second part of a 2-part article that proposes improving the United States (US) clozapine package insert. Part II focuses on fatal outcomes and the 5 boxed warnings, 4 specifically for clozapine: severe neutropenia, seizure, orthostatic hypotension and myocarditis, and 1 for all antipsychotics (elderly with dementia). Methods: US reports to the World Health Organization's global pharmacovigilance database were analyzed from clozapine's introduction to January 15, 2023. Findings/Results: The US was the top reporter worldwide for clozapine with 56,003 reports and 9587 associated fatal outcomes. The 4 clozapine boxed warnings were associated with 534 fatal outcomes (218 …
Every Law School Should Have A Poet, Susan Ayres
Every Law School Should Have A Poet, Susan Ayres
Faculty Scholarship
This is an imaginative work that explores gaslighting in the workplace.
The Antitrust–Copyright Interface In The Age Of Generative Artificial Intelligence, Daryl Lim, Peter K. Yu
The Antitrust–Copyright Interface In The Age Of Generative Artificial Intelligence, Daryl Lim, Peter K. Yu
Faculty Scholarship
The U.S. government's antitrust actions against Big Tech have recently surged in response to the growing dominance of Amazon, Apple, Google, Meta, and Microsoft. In fall 2023, the Federal Trade Commission filed a controversial submission in response to the U.S. Copyright Office's request for comments on artificial intelligence (AI) and copyright. This submission hinted at the agency's eagerness to fully deploy its enforcement powers in the AI sector, including targeting AI developers that have used copyrighted works without authorization to train AI models.
This article examines the changing interface of antitrust and copyright law in the age of generative AI. …
The Sec, Fraud, And Cryptocurrencies, Lawrence J. Trautman, Brian Elzweig, Neal F. Newman
The Sec, Fraud, And Cryptocurrencies, Lawrence J. Trautman, Brian Elzweig, Neal F. Newman
Faculty Scholarship
The SEC’s Strategic Plan for Fiscal Years 2022–2026 is focused on the impact of the rapidly developing rate of change in new technologies that provide for markets to be more interconnected and interdependent than ever. Because Congress has yet to give the SEC, or any other agency, express authority to regulate cryptocurrency, the SEC has taken a regulation-by-enforcement approach. The SEC’s recent enforcement efforts relating to crypto asset securities were substantial, with enforcement actions addressing a range of alleged misconduct in the crypto asset securities space, including billion- dollar crypto fraud schemes; unregistered crypto asset offerings, platforms, and intermediaries; and …