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Fine Structure Of Viral Dsdna Encapsidation, Shawn Walker, Javier Arsuaga, Lindsey Hiltner, M. Carme Calderer, Mariel Vázquez Feb 2020

Fine Structure Of Viral Dsdna Encapsidation, Shawn Walker, Javier Arsuaga, Lindsey Hiltner, M. Carme Calderer, Mariel Vázquez

Faculty Publications

Unraveling the mechanisms of packing of DNA inside viral capsids is of fundamental importance to understanding the spread of viruses. It could also help develop new applications to targeted drug delivery devices for a large range of therapies. In this article, we present a robust, predictive mathematical model and its numerical implementation to aid the study and design of bacteriophage viruses for application purposes. Exploiting the analogies between the columnar hexagonal chromonic phases of encapsidated viral DNA and chromonic aggregates formed by plank-shaped molecular compounds, we develop a first-principles effective mechanical model of DNA packing in a viral capsid. The …

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Agricultural And Finance Intervention Increased Dietary Intake And Weight Of Children Living In Hiv-Affected Households In Western Kenya, Lisa M. Butler, Shiva Bhandari, Phelgona Otieno, Sheri D. Weiser, Craig R. Cohen, Edward A. Frongillo Jr. Feb 2020

Agricultural And Finance Intervention Increased Dietary Intake And Weight Of Children Living In Hiv-Affected Households In Western Kenya, Lisa M. Butler, Shiva Bhandari, Phelgona Otieno, Sheri D. Weiser, Craig R. Cohen, Edward A. Frongillo Jr.

Faculty Publications

We tested whether a multisectoral household agricultural and finance intervention increased the dietary intake and improved the nutritional status of HIV-affected children. Two hospitals in rural Kenya were randomly assigned to be either the intervention or the control arm. The intervention comprised a human-powered water pump, microfinance loan for farm commodities, and training in sustainable farming practices and financial management. In each arm, 100 children (0-59 mo of age) were enrolled from households with HIV-infected adults 18-49 y old. Children were assessed beginning in April 2012 and every 3 mo for 1 y for dietary intake and anthropometry. Children in …

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Energetic And Environmental Constraints On The Community Structure Of Benthic Microbial Mats In Lake Fryxell, Antarctica, Megan L. Dillon, Ian Hawes, Anne D. Jungblut, Tyler J. Mackey, Jonathan A. Eisen, Peter T. Doran, Dawn Y. Sumner Feb 2020

Energetic And Environmental Constraints On The Community Structure Of Benthic Microbial Mats In Lake Fryxell, Antarctica, Megan L. Dillon, Ian Hawes, Anne D. Jungblut, Tyler J. Mackey, Jonathan A. Eisen, Peter T. Doran, Dawn Y. Sumner

Faculty Publications

© 2020 FEMS 2020. Ecological communities are regulated by the flow of energy through environments. Energy flow is typically limited by access to photosynthetically active radiation (PAR) and oxygen concentration (O2). The microbial mats growing on the bottom of Lake Fryxell, Antarctica, have well-defined environmental gradients in PAR and (O2). We analyzed the metagenomes of layers from these microbial mats to test the extent to which access to oxygen and light controls community structure. We found variation in the diversity and relative abundances of Archaea, Bacteria and Eukaryotes across three (O2) and PAR conditions: high (O2) and maximum PAR, variable …

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Improving Construction Work Zone Safety Using Technology: A Systematic Review Of Applicable Technologies, Chukwuma Nnaji, John Gambatese, Hyun Woo Lee, Fan Zhang Feb 2020

Improving Construction Work Zone Safety Using Technology: A Systematic Review Of Applicable Technologies, Chukwuma Nnaji, John Gambatese, Hyun Woo Lee, Fan Zhang

Faculty Publications

© 2019 The Authors Once considered conventional, the construction industry is gradually increasing its reliance on innovations such as the application of technologies in safety management. Given the growing literature on technology applications in safety management and the varying opinions on the utility of applied technologies, a systematic review that streamlines findings from past studies is indispensable to construction stakeholders. Although a number of review studies are available in the building construction sector, the level of fragmentation and uniqueness within the construction industry necessitates a review study specifically targeting the heavy civil sector. In response, the present study applies a …

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230Th Normalization: New Insights On An Essential Tool For Quantifying Sedimentary Fluxes In The Modern And Quaternary Ocean, Kassandra M. Costa, Christopher T. Hayes, Robert F. Anderson, Frank J. Pavia, Alexandra Bausch, Feifei Deng, Jean Claude Dutay, Walter Geibert, Christoph Heinze, Gideon Henderson, Claude Hillaire-Marcel, Sharon Hoffmann, Samuel L. Jaccard, Allison W. Jacobel, Stephanie S. Kienast, Lauren Kipp, Paul Lerner, Jörg Lippold, David Lund, Franco Marcantonio, David Mcgee, Jerry F. Mcmanus, Figen Mekik, Jennifer L. Middleton, Lise Missiaen, Christelle Not, Sylvain Pichat, Laura F. Robinson, George H. Rowland, Matthieu Roy-Barman, Alessandro Tagliabue, Adi Torfstein, Gisela Winckler, Yuxin Zhou Feb 2020

230Th Normalization: New Insights On An Essential Tool For Quantifying Sedimentary Fluxes In The Modern And Quaternary Ocean, Kassandra M. Costa, Christopher T. Hayes, Robert F. Anderson, Frank J. Pavia, Alexandra Bausch, Feifei Deng, Jean Claude Dutay, Walter Geibert, Christoph Heinze, Gideon Henderson, Claude Hillaire-Marcel, Sharon Hoffmann, Samuel L. Jaccard, Allison W. Jacobel, Stephanie S. Kienast, Lauren Kipp, Paul Lerner, Jörg Lippold, David Lund, Franco Marcantonio, David Mcgee, Jerry F. Mcmanus, Figen Mekik, Jennifer L. Middleton, Lise Missiaen, Christelle Not, Sylvain Pichat, Laura F. Robinson, George H. Rowland, Matthieu Roy-Barman, Alessandro Tagliabue, Adi Torfstein, Gisela Winckler, Yuxin Zhou

Faculty Publications

230Th normalization is a valuable paleoceanographic tool for reconstructing high‐resolution sediment fluxes during the late Pleistocene (last ~500,000 years). As its application has expanded to ever more diverse marine environments, the nuances of 230Th systematics, with regard to particle type, particle size, lateral advective/diffusive redistribution, and other processes, have emerged. We synthesized over 1000 sedimentary records of 230Th from across the global ocean at two time slices, the late Holocene (0–5,000 years ago, or 0–5 ka) and the Last Glacial Maximum (18.5–23.5 ka), and investigated the spatial structure of 230Th‐normalized mass fluxes. On a global scale, …

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Experimental Determination Of The Role Of Increased Surface Area In Pool Boiling From Nanostructured Surfaces, Brendon Doran, Bin Zhang, Abigail Walker, Pratik Kc, W. J. Meng, Arden L. Moore Feb 2020

Experimental Determination Of The Role Of Increased Surface Area In Pool Boiling From Nanostructured Surfaces, Brendon Doran, Bin Zhang, Abigail Walker, Pratik Kc, W. J. Meng, Arden L. Moore

Faculty Publications

The use of nanostructured surfaces to enhance pool boiling heat transfer performance has previously been demonstrated for a variety of outwardly-projecting nanostructures such as nanowires and nanotubes. Such enhancement has been attributed to a variety of factors, including greater surface area, improved wickability, and superior nucleation site density as compared to unmodified surfaces. However, since these three phenomena are inherently interlinked with the presence of the nanostructures, isolating each one for independent study to truly understand its relative importance in enhancing pool boiling heat transfer has remained a challenge. In this work, nanoporous anodized aluminum oxide (AAO) films on metallic …

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Effect Of Alloying Elements On The Γ’ Antiphase Boundary Energy In Ni-Base Superalloys, M. Dodaran, A. Hemmasian Ettefagh, S. M. Guo, M. M. Khonsari, W. J. Meng, N. Shamsaei, S. Shao Feb 2020

Effect Of Alloying Elements On The Γ’ Antiphase Boundary Energy In Ni-Base Superalloys, M. Dodaran, A. Hemmasian Ettefagh, S. M. Guo, M. M. Khonsari, W. J. Meng, N. Shamsaei, S. Shao

Faculty Publications

Mechanical and fatigue performance of γ-γ′ Ni-base superalloys are strongly affected by the antiphase boundary energy (APBE) of the γ′ precipitates which, in turn, is dictated by the alloy's composition. Due to the multicomponent character of these alloys, establishing composition-APBE relationships are challenging, even though the qualitative effect of individual solutes on the APBE may be known. This work attempts to utilize density functional theory-based cluster expansion calculations to systematically assess the effect of composition on the APBE of the γ′ phases in Ni-base superalloys. We aim to elucidate the influence of not only one single element but also multiple …

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Investigation Of Microwave-Assisted Pyrolysis Of Biomass With Char In A Rectangular Waveguide Applicator With Built-In Phase-Shifting, Candice Raffaela Ellison, Ryan Hoff, Cosmin Mărculescu, Dorin Boldor Feb 2020

Investigation Of Microwave-Assisted Pyrolysis Of Biomass With Char In A Rectangular Waveguide Applicator With Built-In Phase-Shifting, Candice Raffaela Ellison, Ryan Hoff, Cosmin Mărculescu, Dorin Boldor

Faculty Publications

Fast biomass pyrolysis is a promising technique for thermochemical conversion of biomass into chemicals and biofuels (bio-oil and syngas). Microwave heating can increase process efficiency. The effect of microwave absorber and microwave power level are studied for their effect on pyrolysis process temperature, product yields, and product composition. A novel microwave system was designed with a continuous sliding short enabling phase shifting to mitigate standing wave effects in the low loss load. Pyrolysis experiments on pine sawdust were carried out at varying microwave input powers (600, 900, 1200, and 1500 W) and with varying amounts of biochar added to the …

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Hydromechanical Modelling To Evaluate Impact Of Fault Structure On Co2 Migration In Stacked Storage System, Muhammad Zulqarnain, Mehdi Zeidouni, Richard G. Hughes Feb 2020

Hydromechanical Modelling To Evaluate Impact Of Fault Structure On Co2 Migration In Stacked Storage System, Muhammad Zulqarnain, Mehdi Zeidouni, Richard G. Hughes

Faculty Publications

Faulting processes produce a complex fault damage zone (FDZ) having permeability variations over several orders of magnitude within a very short distance. In this study we use an example normal fault system from a depleted oil field in southern Louisiana with multiple stacked sand beds along the fault structure. Geostatistical techniques are used to introduce heterogeneities of several orders of magnitude over very short distances that honor the across- and along-fault architecture of the system. A total of 15 cases are simulated to account for the impact of a fragmented core, an intact core and a naturally fractured core on …

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Research In Progress: Applied Linguistics At Northern Arizona University, Usa, Brett James Hashimoto, Daniel Keller, Ekaterina Sudina, Katherine Yaw, Jesse Egbert, Luke Plonsky Feb 2020

Research In Progress: Applied Linguistics At Northern Arizona University, Usa, Brett James Hashimoto, Daniel Keller, Ekaterina Sudina, Katherine Yaw, Jesse Egbert, Luke Plonsky

Faculty Publications

Founded in 1990, the Applied Linguistics program at Northern Arizona University (NAU) represents a staple of scholarly activity and graduate training in the field. Indeed, the program, which consists of ten core faculty members and approximately 30 Ph.D. students has been and remains highly active and vibrant in terms of professional/societal involvement and, of course, research. This article highlights recent and current projects carried out by the students and faculty members in the program, divided into five focal areas: corpus linguistics, second language (L2) speech, research methods, second language acquisition (SLA), and psycholinguistics.

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Metrics To Meet Security & Privacy Requirements With Agile Software Development Methods In A Regulated Environment, Torrey J. Wagner, Thomas C. Ford Feb 2020

Metrics To Meet Security & Privacy Requirements With Agile Software Development Methods In A Regulated Environment, Torrey J. Wagner, Thomas C. Ford

Faculty Publications

This work examines metrics that can be used to measure the ability of agile software development methods to meet security and privacy requirements of communications applications. Many implementations of communication protocols, including those in vehicular networks, occur within regulated environments where agile development methods are traditionally discouraged. We propose a framework and metrics to measure adherence to security, quality and software effectiveness regulations if developers desire the cost and schedule benefits of agile methods. After providing an overview of specific challenges that a regulated environment imposes on communications software development, we proceed to examine the 12 agile principles and how …

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Radiation-Induced Electron And Hole Traps In Ge1-XSnX (X = 0-0.094), Michael R. Hogsed, Kevin K. Choe, Norman Miguel, Buguo Wang, John Kouvetakis Feb 2020

Radiation-Induced Electron And Hole Traps In Ge1-XSnX (X = 0-0.094), Michael R. Hogsed, Kevin K. Choe, Norman Miguel, Buguo Wang, John Kouvetakis

Faculty Publications

The band structure of germanium changes significantly when alloyed with a few percent concentrations of tin, and while much work has been done to characterize and exploit these changes, the corresponding deep-level defect characteristics are largely unknown. In this paper, we investigate the dominant deep-level defects created by 2 MeV proton irradiation in Ge1 -xSnx (x = 0.0, 0.020, 0.053, 0.069, and 0.094) diodes and determine how the ionization energies of these defects change with tin concentrations. Deep-level transient spectroscopy measurements approximate the ionization energies associated with electron transitions to/from the valence band (hole traps) and conduction band (electron traps) …

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An Ultra-Sparse Approximation Of Kinetic Solutions To Spatially Homogeneous Flows Of Non-Continuum Gas, Alexander Alekseenko, Amy Grandilli, Aihua W. Wood Feb 2020

An Ultra-Sparse Approximation Of Kinetic Solutions To Spatially Homogeneous Flows Of Non-Continuum Gas, Alexander Alekseenko, Amy Grandilli, Aihua W. Wood

Faculty Publications

We consider a compact approximation of the kinetic velocity distribution function by a sum of isotropic Gaussian densities in the problem of spatially homogeneous relaxation. Derivatives of the macroscopic parameters of the approximating Gaussians are obtained as solutions to a linear least squares problem derived from the Boltzmann equation with full collision integral. Our model performs well for flows obtained by mixing upstream and downstream conditions of normal shock wave with Mach number 3. The model was applied to explore the process of approaching equilibrium in a spatially homogeneous flow of gas. Convergence of solutions with respect to the model …

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Harmonic Equiangular Tight Frames Comprised Of Regular Simplices, Matthew C. Fickus, Courtney A. Schmitt Feb 2020

Harmonic Equiangular Tight Frames Comprised Of Regular Simplices, Matthew C. Fickus, Courtney A. Schmitt

Faculty Publications

An equiangular tight frame (ETF) is a sequence of unit-norm vectors in a Euclidean space whose coherence achieves equality in the Welch bound, and thus yields an optimal packing in a projective space. A regular simplex is a simple type of ETF in which the number of vectors is one more than the dimension of the underlying space. More sophisticated examples include harmonic ETFs which equate to difference sets in finite abelian groups. Recently, it was shown that some harmonic ETFs are comprised of regular simplices. In this paper, we continue the investigation into these special harmonic ETFs. We begin …

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Disruptive Innovation: Impact For Practice, Policy, And Academia, Heather V. Nelson-Brantley, K. David Bailey, Joyce Batcheller, Laura Caramanica, Bret Lyman, Francine Snow Feb 2020

Disruptive Innovation: Impact For Practice, Policy, And Academia, Heather V. Nelson-Brantley, K. David Bailey, Joyce Batcheller, Laura Caramanica, Bret Lyman, Francine Snow

Faculty Publications

The 2019 Association for Leadership Science in Nursing International Conference, Disruptive Innovation, was held in Los Angeles, California, with attendees from 30 US States, Canada, Brazil, and China. Presenters discussed the need for nurse leaders to advocate for health equity, lead evidence-based innovation, how robots and other technology are generating disruptive innovations in healthcare, and building strong academic-practice partnerships to address nursing workforce challenges. This article will report on these important insights.

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Kinetic Alfvénwaves Frommagnetotail To The Ionosphere In Global Hybrid Simulation Associated With Fast Flows, Lei Cheng, Yu Lin, J. D. Perez, Jay R. Johnson, Xueyi Wang Feb 2020

Kinetic Alfvénwaves Frommagnetotail To The Ionosphere In Global Hybrid Simulation Associated With Fast Flows, Lei Cheng, Yu Lin, J. D. Perez, Jay R. Johnson, Xueyi Wang

Faculty Publications

We have used the Auburn Global Hybrid Code in 3‐D to study the generation, dynamics, and global structure of kinetic Alfvén waves (KAWs) from the magnetotail to the ionosphere. Our results show that KAWs are generated in magnetic reconnection in the plasma sheet, located around fast flows, and carrying transverse electromagnetic perturbations, parallel Poynting fluxes, parallel currents, and parallel electric field. Overall, shear Alfvénic turbulent spectrum is found in the plasma sheet. The KAWs are shear Alfvén waves possessing short perpendicular wavelength with , where is the perpendicular wave number and the ion Larmor radius. The KAWs are identified by …

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Emerging Decolonialized Research Collaboration: The Max Planck Society And The Leibniz Association In Latin America, Pedro Pineda, Gustavo Gregorutti, Bernhard Streitwieser Feb 2020

Emerging Decolonialized Research Collaboration: The Max Planck Society And The Leibniz Association In Latin America, Pedro Pineda, Gustavo Gregorutti, Bernhard Streitwieser

Faculty Publications

Analyzing the number of publications and proportion of corresponding authors of Latin American scholars and scholars from the German Max Planck Society (MPS) and the Leibniz Association (LA; 1954–2018), this article asks if North–South partnerships continue to represent power imbalances. Our bibliometric analysis indicates that (a) in comparison with the LA, the MPS’s scientists published more articles with Latin American countries, led by Brazil, Chile, Argentina, and Mexico; (b) researchers from the MPS and the LA frequently took the role of corresponding author; (c) researchers from Brazil, Chile, Argentina, and Mexico primarily controlled their region’s productivity, but (d) Brazil built …

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A Sequential Partial Information Bomber‐Defender Shooting Problem, Krishna Kalyanam, David W. Casbeer, Meir Pachter Feb 2020

A Sequential Partial Information Bomber‐Defender Shooting Problem, Krishna Kalyanam, David W. Casbeer, Meir Pachter

Faculty Publications

No abstract provided.

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Community Sentiment Following The Deepwater Horizon Oil Spill Disaster: A Test Of Time, Systemic Community, And Corrosive Community Models, Michael R. Cope, Tim Slack, Jorden E. Jackson, Vanessa Parks Feb 2020

Community Sentiment Following The Deepwater Horizon Oil Spill Disaster: A Test Of Time, Systemic Community, And Corrosive Community Models, Michael R. Cope, Tim Slack, Jorden E. Jackson, Vanessa Parks

Faculty Publications

A fundamental concern in the social science scholarship on disasters is understanding community impacts and recovery as a social process. This study examines community sentiment in the aftermath 2010 BP Deepwater Horizon oil spill (DHOS), including the influence of time and the explanatory utility of two major theoretical perspectives—the systemic community model and the corrosive community model—in predicting community sentiment in the context of this disaster. Specifically, our objectives are to assess how community sentiment in the wake of the DHOS: 1) changes over time; 2) is related to the systemic model; and 3) is related to the corrosive model. …

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The Washington State Second Chance Expungement Gap, Colleen Chien, Zuyan Huang, Jacob Kuykendall, Katie Rabago Jan 2020

The Washington State Second Chance Expungement Gap, Colleen Chien, Zuyan Huang, Jacob Kuykendall, Katie Rabago

Faculty Publications

Every time a person is convicted of a crime, this event is memorialized in the person’s criminal record in perpetuity, setting off thousands of potential collateral consequences, including being penalized in searches for employment, housing and volunteer opportunities. To remove these harmful consequences, Washington law allows people whose criminal records meet certain conditions to vacate their records. However, the Second Chance Gap in Washington “expungements” - the share of people who aren’t accessing the vacation remedy because of hurdles in the petition process - we suspect is large. To estimate it, we used research and practice expertise to approximately model …

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Highly Active Cationic Cobalt(Ii) Hydroformylation Catalysts, Drew M. Hood, Ryan A. Johnson, Alex E. Carpenter, Jarod M. Younker, David J. Vinyard, George G. Stanley Jan 2020

Highly Active Cationic Cobalt(Ii) Hydroformylation Catalysts, Drew M. Hood, Ryan A. Johnson, Alex E. Carpenter, Jarod M. Younker, David J. Vinyard, George G. Stanley

Faculty Publications

© 2020 American Association for the Advancement of Science. All rights reserved. The cobalt complexes HCo(CO)4 and HCo(CO)3(PR3) were the original industrial catalysts used for the hydroformylation of alkenes through reaction with hydrogen and carbon monoxide to produce aldehydes. More recent and expensive rhodium-phosphine catalysts are hundreds of times more active and operate under considerably lower pressures. Cationic cobalt(II) bisphosphine hydrido-carbonyl catalysts that are far more active than traditional neutral cobalt(I) catalysts and approach rhodium catalysts in activity are reported here. These catalysts have low linear-to-branched (L:B) regioselectivity for simple linear alkenes. However, owing to their high alkene isomerization activity …

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Generating Electromagnetic Dark And Antidark Partially Coherent Sources, Milo W. Hyde Iv Jan 2020

Generating Electromagnetic Dark And Antidark Partially Coherent Sources, Milo W. Hyde Iv

Faculty Publications

We present two methods to generate an electromagnetic dark and antidark partially coherent source. The first generalizes a recently published scalar approach by representing the stochastic electric field vector components as sums of randomly weighted, randomly tilted plane waves. The second method expands the field’s vector components in series of randomly weighted dark and antidark coherent modes. The statistical moments of the random weights—plane waves in the former method, coherent modes in the latter—are found by comparing the resulting means and covariances to those of the desired electromagnetic dark and antidark source. We validate both methods by simulating the generation …

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Γ -Ray Spectroscopy Of Astrophysically Important States In Ca 39, M. R. Hall, D. W. Bardayan, T. Baugher, A. Lepailleur, S. D. Pain, A. Ratkiewicz, S. Ahn, J. M. Allen, J. T. Anderson, A. D. Ayangeakaa, J. C. Blackmon, S. Burcher, M. P. Carpenter, S. M. Cha, K. Y. Chae, K. A. Chipps, J. A. Cizewski, M. Febbraro, O. Hall, J. Hu, C. L. Jiang, K. L. Jones, E. J. Lee, P. D. O'Malley, S. Ota, B. C. Rasco, D. Santiago-Gonzalez, D. Seweryniak, H. Sims, K. Smith, W. P. Tan, P. Thompson, C. Thornsberry Jan 2020

Γ -Ray Spectroscopy Of Astrophysically Important States In Ca 39, M. R. Hall, D. W. Bardayan, T. Baugher, A. Lepailleur, S. D. Pain, A. Ratkiewicz, S. Ahn, J. M. Allen, J. T. Anderson, A. D. Ayangeakaa, J. C. Blackmon, S. Burcher, M. P. Carpenter, S. M. Cha, K. Y. Chae, K. A. Chipps, J. A. Cizewski, M. Febbraro, O. Hall, J. Hu, C. L. Jiang, K. L. Jones, E. J. Lee, P. D. O'Malley, S. Ota, B. C. Rasco, D. Santiago-Gonzalez, D. Seweryniak, H. Sims, K. Smith, W. P. Tan, P. Thompson, C. Thornsberry

Faculty Publications

Background: Nova explosions synthesize elements up to A≃40, and discrepancies exist between calculated and observed abundances of Ar and Ca created in the explosion. The K38(p,γ)Ca39 reaction rate has been shown to be influential on these isotopic abundances at the endpoint of nova nucleosynthesis. The energies of the three most important resonances, corresponding to Jπ=5/2+ excited states in the Ca39 nucleus above the proton separation threshold, are uncertain and one has been measured with conflicting values [Er=679(2) versus Er=701(2) keV] in previous experiments. Purpose: Reducing the uncertainties on the resonance energies would allow for a better understanding of the reaction …

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Physics Of Nuclei: Key Role Of An Emergent Symmetry, T. Dytrych, K. D. Launey, J. P. Draayer, D. J. Rowe, J. L. Wood, G. Rosensteel, C. Bahri, D. Langr, R. B. Baker Jan 2020

Physics Of Nuclei: Key Role Of An Emergent Symmetry, T. Dytrych, K. D. Launey, J. P. Draayer, D. J. Rowe, J. L. Wood, G. Rosensteel, C. Bahri, D. Langr, R. B. Baker

Faculty Publications

We show through first-principles nuclear structure calculations that the special nature of the strong nuclear force determines highly regular patterns heretofore unrecognized in nuclei that can be tied to an emergent approximate symmetry. This symmetry is ubiquitous and mathematically tracks with a symplectic symmetry group. This, in turn, has important implications for understanding the physics of nuclei: we find that nuclei are made of only a few equilibrium shapes, deformed or not, with associated vibrations and rotations. It also opens the path for ab initio large-scale modeling of open-shell intermediate-mass nuclei without the need for renormalized interactions and effective charges.

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Recombination And Gene Loss Occur Simultaneously During Bacterial Horizontal Gene Transfer, Bert Ely Jan 2020

Recombination And Gene Loss Occur Simultaneously During Bacterial Horizontal Gene Transfer, Bert Ely

Faculty Publications

Bacteria can acquire new genes by incorporating environmental DNA into their genomes, yet genome sizes stay relatively constant. In nature, gene acquisition is a rare event so it is difficult to observe. However, the Caulobacter crescentus CB2A genome contains 114 insertions of genetic material from the closely-related NA1000 strain, providing a unique opportunity to analyze the horizontal transfer of genetic material. Analyses of these insertions led to a new model that involves preferential recombination at non-homologous regions that are flanked by regions of homology and does not involve any mutational processes. The net result is the replacement of segments of …

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Phylogenetic Afficity Of Genolopa (Digenea: Monorchiidae) With Descriptions Of Two New Species, Apryle J. Panyi, Stephen S. Curran, Robin M. Overstreet Jan 2020

Phylogenetic Afficity Of Genolopa (Digenea: Monorchiidae) With Descriptions Of Two New Species, Apryle J. Panyi, Stephen S. Curran, Robin M. Overstreet

Faculty Publications

The validity of Genolopa Linton, 1910 has been controversial because the observation of presently recognized critical diagnostic morphological features (spines in the genital atrium and a bipartite, anteriorly spined terminal organ) were omitted from the original diagnosis, and these features were not universally appreciated as important diagnostic features until 2008. Modern taxonomists have been further challenged by inappropriate fixation techniques that have resulted in various interpretations of morphological features. Consequently, named species in the genus have fluctuated among other monorchiid genera depending on various interpretations by taxonomists, and a modern consensus on classifying these species is lacking. This study …

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Functional And Transcriptomic Characterization Of Cisplatin-Resistant Ags And Mkn-28 Gastric Cancer Cell Lines, Barbara Mora-Lagos, Irene Cartas-Espinel, Ismael Riquelme, Alyssa C. Parker, Stephen R. Piccolo, Tamara Viscarra, Maria Elena Reyes, Louise Zanella, Kurt Buchegger, Carmen Ili, Priscilla Brebi Jan 2020

Functional And Transcriptomic Characterization Of Cisplatin-Resistant Ags And Mkn-28 Gastric Cancer Cell Lines, Barbara Mora-Lagos, Irene Cartas-Espinel, Ismael Riquelme, Alyssa C. Parker, Stephen R. Piccolo, Tamara Viscarra, Maria Elena Reyes, Louise Zanella, Kurt Buchegger, Carmen Ili, Priscilla Brebi

Faculty Publications

Gastric cancer (GC) is a significant cancer-related cause of death worldwide. The most used chemotherapeutic regimen in GC is based on platinum drugs such as cisplatin (CDDP). However, CDDP resistance reduces advanced GC survival. In vitro drug-resistant cell model would help in the understanding of molecular mechanisms underlying this drug-resistance phenomenon. The aim of this study was to characterize new models of CDDP-resistant GC cell lines (AGS R-CDDP and MKN-28 R-CDDP) obtained through a stepwise increasing drug doses method, in order to understand the molecular mechanisms underlying chemoresistance as well as identify new therapeutic targets for the treatment of GC. …

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Entanglement And Secret-Key-Agreement Capacities Of Bipartite Quantum Interactions And Read-Only Memory Devices, Siddhartha Das, Stefan Bäuml, Mark M. Wilde Jan 2020

Entanglement And Secret-Key-Agreement Capacities Of Bipartite Quantum Interactions And Read-Only Memory Devices, Siddhartha Das, Stefan Bäuml, Mark M. Wilde

Faculty Publications

A bipartite quantum interaction corresponds to the most general quantum interaction that can occur between two quantum systems in the presence of a bath. In this work, we determine bounds on the capacities of bipartite interactions for entanglement generation and secret-key agreement between two quantum systems. Our upper bound on the entanglement generation capacity of a bipartite quantum interaction is given by a quantity called the bidirectional max-Rains information. Our upper bound on the secret-key-agreement capacity of a bipartite quantum interaction is given by a related quantity called the bidirectional max-relative entropy of entanglement. We also derive tighter upper bounds …

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Green Edge Ice Camp Campaigns: Understanding The Processes Controlling The Under-Ice Arctic Phytoplankton Spring Bloom, Philippe Massicotte, Rémi Amiraux, Marie-Pier Amyot, Philippe Archambault, Mathieu Ardyna, Laurent Arnaud, Lise Artigue, Cyril Aubry, Pierre Ayotte, Guislain Bécu, Simon Bélanger, Ronald Benner, Henry C. Bittig, Annick Bricaud, Éric Brossier, Flavienne Bruyant, Et. Al. Jan 2020

Green Edge Ice Camp Campaigns: Understanding The Processes Controlling The Under-Ice Arctic Phytoplankton Spring Bloom, Philippe Massicotte, Rémi Amiraux, Marie-Pier Amyot, Philippe Archambault, Mathieu Ardyna, Laurent Arnaud, Lise Artigue, Cyril Aubry, Pierre Ayotte, Guislain Bécu, Simon Bélanger, Ronald Benner, Henry C. Bittig, Annick Bricaud, Éric Brossier, Flavienne Bruyant, Et. Al.

Faculty Publications

The Green Edge initiative was developed to investigate the processes controlling the primary productivity and fate of organic matter produced during the Arctic phytoplankton spring bloom (PSB) and to determine its role in the ecosystem. Two field campaigns were conducted in 2015 and 2016 at an ice camp located on landfast sea ice southeast of Qikiqtarjuaq Island in Baffin Bay (67.4797∘ N, 63.7895∘ W). During both expeditions, a large suite of physical, chemical and biological variables was measured beneath a consolidated sea-ice cover from the surface to the bottom (at 360 m depth) to better understand the factors driving the …

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A Transcriptional Regulatory System Of The S. Cerevisiae Ole1 Gene Responds To Fatty Acid Species And Intracellular Amount, And Not Simply Membrane Status, Marshall Willey, Matthew Ochs, Clara Schriemer, Virginia Mcdonough Jan 2020

A Transcriptional Regulatory System Of The S. Cerevisiae Ole1 Gene Responds To Fatty Acid Species And Intracellular Amount, And Not Simply Membrane Status, Marshall Willey, Matthew Ochs, Clara Schriemer, Virginia Mcdonough

Faculty Publications

We examined the effects of unsaturated fatty acid (UFA) species and their concentration on the expression of OLE1, which encodes the stearoyl CoA desaturase, in Saccharomyces cerevisiae. We controlled the amount of UFA taken up by the cell by varying the concentration of tergitol in the medium. When cultured with 1 mM fatty acid in 0.1% tergitol, cells took up much more fatty acid than when cultured with the same concentration of fatty acid at 1% tergitol, although the amount incorporated was dependent on UFA species. For each fatty acid tested, we found that the higher uptake (0.1% tergitol condition) …

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