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Lack Of Association Between A Biallelic Polymorphism In The Adducin Gene And Blood Pressure In Whites And African Americans, Nicholas J. Schork, Aravinda Chakravarti, Bonnie Thiel, Myriam Fornage, Howard J. Jacob, Robin Cai, Charles N. Rotimi, Richard S. Cooper, Alan B. Weder Jan 2000

Lack Of Association Between A Biallelic Polymorphism In The Adducin Gene And Blood Pressure In Whites And African Americans, Nicholas J. Schork, Aravinda Chakravarti, Bonnie Thiel, Myriam Fornage, Howard J. Jacob, Robin Cai, Charles N. Rotimi, Richard S. Cooper, Alan B. Weder

Faculty Publications

Population-based candidate gene association analyses are becoming increasingly popular as a result of a greater number of genes and gene polymorphisms having been identified for which some functional information is available. Because many biochemical and physiologic systems impact blood pressure regulation and hypertension susceptibility, many of these identified genes and polymorphisms are candidates for population-level association studies involving blood pressure levels or hypertension status. Recent studies have suggested that the α-adducin gene may harbor polymorphisms that influence blood pressure level. Therefore, we embarked on a study to test one such polymorphism in two large US samples: one from an urban …


Effect Of Silicon Rate And Host Resistance On Blast, Scald, And Yield Of Upland Price, K. W. Seebold, L. E. Datnoff, F. J. Correa-Victoria, T. A. Kucharek, G. H. Snyder Jan 2000

Effect Of Silicon Rate And Host Resistance On Blast, Scald, And Yield Of Upland Price, K. W. Seebold, L. E. Datnoff, F. J. Correa-Victoria, T. A. Kucharek, G. H. Snyder

Faculty Publications

Blast-resistant, partially resistant, and susceptible cultivars of rice were planted in soil amended with Si at 0, 500, or 1,000 kg/ha at two locations in eastern Colombia to assess differential responses to leaf blast, neck blast, and leaf scald, and to examine the quantity and quality of grains harvested. Leaf and neck blast on partially resistant and susceptible cultivars were reduced by Si as the rate of Si was increased. Depending on the location, the level of severity of leaf and neck blast on partially resistant cultivars, when fertilized with Si at 500 or 1,000 kg/ha, was lowered to that …


Movement And Territoriality Of Wintering Hermit Thrushes In Southeastern Louisiana, David R. Brown, Philip C. Stouffer, Cheryl M. Strong Jan 2000

Movement And Territoriality Of Wintering Hermit Thrushes In Southeastern Louisiana, David R. Brown, Philip C. Stouffer, Cheryl M. Strong

Faculty Publications

We describe the spatial organization and social behavior of Hermit Thrushes (Catharus guttatus) wintering in pine plantations and an adjacent hardwood forest in Tangipahoa Parish, Louisiana over three winters. We used point counts (n = 403) to collect data on agonistic behaviors and relative abundance within the study area. We used mist-netting to study site fidelity on four 9-ha plots within and among years. We used radio-telemetry to measure Hermit Thrushes' movements and territoriality (n = 50). We found that Hermit Thrushes saturated suitable patches within the study area. Most Hermit Thrushes actively defended small [mean = 0.55 ± 0.03 …


Acifluorfen Sorption, Degradation, And Mobility In A Mississippi Delta Soil, L. A. Gaston, M. A. Locke Jan 2000

Acifluorfen Sorption, Degradation, And Mobility In A Mississippi Delta Soil, L. A. Gaston, M. A. Locke

Faculty Publications

Potential surface water and groundwater contaminants include herbicides that are applied postemergence. Although applied to the plant canopy, a portion of any application reaches the soil either directly or via subsequent foliar washoff. This study examined sorption, degradation, and mobility of the postemergence herbicide acifluorfen (5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitrobenzoic acid) in Dundee silty clay loam (fine-silty, mixed, thermic, Aeric Ochraqualf) taken from conventional till (CT) and no-till (NT) field plots. Homogeneous surface and subsurface samples were used in the sorption and degradation studies; intact soil columns (30 cm long and 10 cm diam.) were used in the mobility study. Batch sorption isotherms were …


Chromosome 17 Aneusomy Detected By Fluorescence In Situ Hybridization In Vulvar Squamous Cell Carcinomas And Synchronous Vulvar Skin, J. Andrew Carlson, Kara Healy, Tien Anh Tran, John Malfetano, Vincent L. Wilson, Angela Rohwedder, Jeffrey S. Ross Jan 2000

Chromosome 17 Aneusomy Detected By Fluorescence In Situ Hybridization In Vulvar Squamous Cell Carcinomas And Synchronous Vulvar Skin, J. Andrew Carlson, Kara Healy, Tien Anh Tran, John Malfetano, Vincent L. Wilson, Angela Rohwedder, Jeffrey S. Ross

Faculty Publications

Vulvar squamous cell carcinoma (SCC) affects a spectrum of women with granulomatous vulvar diseases, human papillomavirus (HPV) infections, and chronic inflammatory vulvar dermatoses. To determine whether there is evidence of chromosomal instability occurring in synchronous skin surrounding vulvar SCCs, we investigated abnormalities in chromosome 17 copy number. Samples of SCC, vulvar intraepithelial neoplasia (VIN), and surrounding vulvar skin were obtained from all vulvar excisions performed for squamous neoplasia at Albany Medical College from 1996 to 1997. Histological categorization, fluorescent in situ hybridization (FISH) for the α satellite region of chromosome 17, DNA content by image analysis, and Ki-67 labeling were …


Regulating Consenseual Sex With Minors: Defining A Role For Statutory Rape, Michelle Oberman Jan 2000

Regulating Consenseual Sex With Minors: Defining A Role For Statutory Rape, Michelle Oberman

Faculty Publications

No abstract provided.


Conceptual Clarification And Policy-Related Science: The Case Of Chemical Hormesis, Kevin C. Elliott Jan 2000

Conceptual Clarification And Policy-Related Science: The Case Of Chemical Hormesis, Kevin C. Elliott

Faculty Publications

This paper examines the epistemological warrant for a toxicological phenomenon known as chemical hormesis. First, it argues that conceptual confusion contributes significantly to current disagreements about the status of chemical hormesis as a biological hypothesis. Second, it analyzes seven distinct concepts of chemical hormesis, arguing that none are completely satisfactory. Finally, it suggests three ramifications of this analysis for ongoing debates about the epistemological status of chemical hormesis. This serves as a case study supporting the value of philosophical methodologies such as conceptual clarification for addressing contemporary scientific disputes, including policy-related scientific disputes that may be heavily influencedby social and …


More Sorry Than Safe: Assessing The Precautionary Principle And The Proposed International Biosafety Protocol, Jonathan H. Adler Jan 2000

More Sorry Than Safe: Assessing The Precautionary Principle And The Proposed International Biosafety Protocol, Jonathan H. Adler

Faculty Publications

Part I of this paper provides a brief overview of the development of biotechnology, its regulation and its use, with a particular emphasis on agricultural biotechnology. Part II outlines the United Nations Convention on Biological Diversity, which provides an international legal framework for a biosafety protocol and summarizes the results of recent protocol negotiations, such as those conducted in Cartagena, Colombia in February 1999, which continued in Montreal in January 2000. Part III explains why the proposed protocol embodies a variant of the precautionary principle and why such policies may do more harm than good. This paper concludes with some …


The Pathology Of Property Norms: Living Within Nature's Boundaries, Lynda L. Butler Jan 2000

The Pathology Of Property Norms: Living Within Nature's Boundaries, Lynda L. Butler

Faculty Publications

No abstract provided.


The World Trade Constitution, John O. Mcginnis, Mark L. Movsesian Jan 2000

The World Trade Constitution, John O. Mcginnis, Mark L. Movsesian

Faculty Publications

Conventional wisdom holds that the World Trade Organization (WTO) necessarily poses a threat to sovereignty and representative government within its member nations. Professors McGinnis and Movsesian refute this view. They argue that the WTO can be understood as a constitutive structure that, by reducing the power of protectionist interest groups, can simultaneously promote international trade and domestic democracy. Indeed, in promoting both free trade and accountable government, the WTO reflects many of the insights that inform our own Madisonian Constitution. Professors McGinnis and Movsesian reject recent proposals to grant the WTO regulatory authority, endorsing instead the WTO's limited adjudicative power …


Reclaiming The "Creatures Of The State": Contracting For Child Custody Decisionmaking In The Best Interests Of The Family, E. Gary Spitko Jan 2000

Reclaiming The "Creatures Of The State": Contracting For Child Custody Decisionmaking In The Best Interests Of The Family, E. Gary Spitko

Faculty Publications

Arbitration has great potential utility for promoting family autonomy. Parents in a fracturing family might utilize arbitration to select both the decisionmaker and the legal standards to guide that decisionmaker in resolving their child custody and visitation dispute. In this way, the parents can seek to ensure that the resolution of their child custody and visitation dispute is governed by the values that the family has cherished and lived by.

The present dominant judicial approaches to the enforcement of arbitration agreements and awards with respect to child custody, however, greatly undermine arbitration's utility for promoting family autonomy. Pursuant to the …


Parental Rights Termination Jurisprudence: Questioning The Framework, Jennifer Wriggins Jan 2000

Parental Rights Termination Jurisprudence: Questioning The Framework, Jennifer Wriggins

Faculty Publications

The article analyzes the Supreme Court’s decision in M.L.B. v. S.L.J., 519 U.S. 102 (1996), which held that where a state provides an appeal from a judgment terminating parental rights, it must, under the due process and equal protection clauses provide indigent appellants with a transcript if a transcript is necessary to review the decision. In doing so, it questions the framework used to analyze parental rights termination decisions. Specifically, it questions the sharp line drawn between cases concerning termination of parental rights (in which parents have certain constitutional protections) and cases concerning child custody (in which parents lack those …


Girls In The Master's House: Of Protection, Patriarchy And The Potential For Using The Master's Tools To Reconfigure Statutory Rape Law, Michelle Oberman Jan 2000

Girls In The Master's House: Of Protection, Patriarchy And The Potential For Using The Master's Tools To Reconfigure Statutory Rape Law, Michelle Oberman

Faculty Publications

No abstract provided.


Threatened Fishes Of The World: Chasmistes Liorus Jordan, 1878 (Catostomidae), Mike Whitney, Mark C. Belk Jan 2000

Threatened Fishes Of The World: Chasmistes Liorus Jordan, 1878 (Catostomidae), Mike Whitney, Mark C. Belk

Faculty Publications

Common name: June sucker.


Spatio-Temporal Distribution Of Larval Gobiosoma Bosc In Waters Adjacent To Natural And Altered Marsh-Edge Habitats Of Mississippi Coastal Waters, J. Read Hendon, Mark S. Peterson, Bruce H. Comyns Jan 2000

Spatio-Temporal Distribution Of Larval Gobiosoma Bosc In Waters Adjacent To Natural And Altered Marsh-Edge Habitats Of Mississippi Coastal Waters, J. Read Hendon, Mark S. Peterson, Bruce H. Comyns

Faculty Publications

Larval naked gobies, Gobiosoma bose, were collected monthly from October 1995 to September 1997 by beam plankton trawl from waters adjacent to natural Juncus/Spartina marsh-edge, natural sandy beach and altered Juncus/Spartina marsh-edge habitats in Mississippi coastal waters. Altered marsh habitats consisted of two bulkheaded stations and one stretch of riprap. Abundances were significantly higher in waters adjacent to natural marsh-edge habitats than in those adjacent to altered habitats in year one (P = 0.011), suggesting that the physical nature of alteration may have caused reduced habitat suitability. Abundances also varied seasonally, with summer conditions of high water temperature, increasing tide …


On Children And Dual Nationality: Sabet And The Islamic Republic Of Iran, Nancy Amoury Combs Jan 2000

On Children And Dual Nationality: Sabet And The Islamic Republic Of Iran, Nancy Amoury Combs

Faculty Publications

The Iran-United States Claims Tribunal's recent decision in Sabet and The Islamic Republic of Iran sheds new light on difficult issues concerning the dual nationality of minors. In particular, the case was the first in which the Tribunal determined minor dual national claimants to have a dominant and effective nationality different from that of either of their parents. Further, the Tribunal broke new ground in its analysis of 'the caveat,' an equitable doctrine that can bar the claims of dual nationals. This article applauds the Tribunal's advances in its caveat jurisprudence and develops a new approach that would further those …


A Mathematical Model For Spatially Varying Extracellular Matrix, J. C. Dallon, J. A. Sherratt Jan 2000

A Mathematical Model For Spatially Varying Extracellular Matrix, J. C. Dallon, J. A. Sherratt

Faculty Publications

Orientation of extracellular matrix fibers in the skin is a key ingredient of tissue appearance and function, and differences in fiber alignment are one of the main distinctions between scar tissue and normal skin. In this paper, the authors develop a mathematical model for alignment of collagen fibers and the fibroblast cells that remodel them; the model extends previous work in which spatial variation was excluded. Numerical simulations of the model are presented, which show spatial variations in alignment over long transients, but with spatially uniform behavior in the long term. This is investigated further via asymptotic analysis, using the …


Proclamation-Based Principles Of Parenting And Supportive Scholarship, Craig H. Hart, Lloyd D. Newell, Lisa L. Sine Jan 2000

Proclamation-Based Principles Of Parenting And Supportive Scholarship, Craig H. Hart, Lloyd D. Newell, Lisa L. Sine

Faculty Publications

How parents view the nature of a child and their own role as parents has great influence over the life of that child. Many perspectives about the nature of children have arisen in the course of Western Civilization that have shaped childrearing practices for centuries, including the increasingly accepted scholarly view that parents matter relatively little in children’s lives. (2) This chapter emphasizes inspired, eternal principles that are supported by empirical and conceptual scholarship, which suggests that optimal parenting does indeed matter in children’s lives.


Diet Of Gambelia Wislizenii From Chihuahua, Mexico, J. A. Lemos-Espinal, Geoffrey R. Smith, H. M. Smith, R. E. Ballinger Jan 2000

Diet Of Gambelia Wislizenii From Chihuahua, Mexico, J. A. Lemos-Espinal, Geoffrey R. Smith, H. M. Smith, R. E. Ballinger

Faculty Publications

No abstract provided.


Effects Of Age And Group Size On Habitat Selection And Activity Level In Xenopus Laevis Tadpoles, D. R. Golden, Geoffrey R. Smith, Jessica E. Rettig Jan 2000

Effects Of Age And Group Size On Habitat Selection And Activity Level In Xenopus Laevis Tadpoles, D. R. Golden, Geoffrey R. Smith, Jessica E. Rettig

Faculty Publications

No abstract provided.


A Biblical Theology Of The Flood, Richard M. Davidson Jan 2000

A Biblical Theology Of The Flood, Richard M. Davidson

Faculty Publications

No abstract provided.


The Effects Of Forest Fragment Size, Isolation, And Microhabitat Variables On Nest Box Use By Southern Flying Squirrels (Glaucomys Volans) In Southern Illinois, Catherine Wong, Eric K. Bollinger, Thomas A. Nelson Jan 2000

The Effects Of Forest Fragment Size, Isolation, And Microhabitat Variables On Nest Box Use By Southern Flying Squirrels (Glaucomys Volans) In Southern Illinois, Catherine Wong, Eric K. Bollinger, Thomas A. Nelson

Faculty Publications

We studied the effects of forest fragmentation on southern flying squirrels (Glaucomys volans) in southern Illinois, and examined factors influencing nest box use. Ten nest boxes were placed in each of 30 oak-hickory forest fragments. Nest boxes were checked monthly after installation. We measured habitat variables that described the nest box tree, the microhabitat surrounding the nest box tree, and landscape level characteristics of the fragments (isolation and area). Overall, 78% of the 300 nest boxes were used. Glaucomys volans was captured in 24 of the 30 forest fragments, and evidence of squirrel use was found in 4 additional fragments. …


Zooarchaeology, Susan L. Scott Jan 2000

Zooarchaeology, Susan L. Scott

Faculty Publications

No abstract provided.


A Biblical Theology Of Creation, Richard M. Davidson Jan 2000

A Biblical Theology Of Creation, Richard M. Davidson

Faculty Publications

No abstract provided.


Sensitivity Of A High‐Elevation Rocky Mountain Watershed To Altered Climate And Co2, Jill S. Baron, Melannie D. Hartman, L. E. Band, Richard B. Lammers Jan 2000

Sensitivity Of A High‐Elevation Rocky Mountain Watershed To Altered Climate And Co2, Jill S. Baron, Melannie D. Hartman, L. E. Band, Richard B. Lammers

Faculty Publications

We explored the hydrologic and ecological responses of a headwater mountain catchment, Loch Vale watershed, to climate change and doubling of atmospheric CO2 scenarios using the Regional Hydro‐Ecological Simulation System (RHESSys). A slight (2°C) cooling, comparable to conditions observed over the past 40 years, led to greater snowpack and slightly less runoff, evaporation, transpiration, and plant productivity. An increase of 2°C yielded the opposite response, but model output for an increase of 4°C showed dramatic changes in timing of hydrologic responses. The snowpack was reduced by 50%, and runoff and soil water increased and occurred 4–5 weeks earlier with 4°C …


Food Resources Of Stream Macroinvertebrates Determined By Natural-Abundance Stable C And N Isotopes And A 15n Tracer Addition, Patrick J. Mulholland, Jennifer L. Tank, Diane M. Sanzone, Wilfred M. Wollheim, Bruce J. Peterson, Jackson R. Webster, Judy L. Meyer Jan 2000

Food Resources Of Stream Macroinvertebrates Determined By Natural-Abundance Stable C And N Isotopes And A 15n Tracer Addition, Patrick J. Mulholland, Jennifer L. Tank, Diane M. Sanzone, Wilfred M. Wollheim, Bruce J. Peterson, Jackson R. Webster, Judy L. Meyer

Faculty Publications

Trophic relationships were examined using natural-abundance 13C and 15N analyses and a 15N-tracer addition experiment in Walker Branch, a 1st-order forested stream in eastern Tennessee. In the 15N-tracer addition experiment, we added 15NH4, to stream water over a 6-wk period In early spring, and measured 15N:14N ratios in different taxa and biomass compartments over distance and time. Samples collected from a station upstream from the 15N addition provided data on natural-abundance 13C:12C and 15N:14N ratios. The natural-abundance 15N analysis proved to be of limited value in identifying food resources of macroinvertebrates because 15N values were not greatly different among food …


Effect Of Smoking On The Body Mass Index-Mortality Relation: Empirical Evidence From 15 Studies, V. Hawthorne, V. Hawthorne, D. Kozarevic, N. Vojvodic, C. R. Gillis, D. Hole, C. Hart, T. Jorgensen, T. Thomsen, M. Davidson, U. Goldbourt, S. Yaari, G. Cao, R. Cooper, R. Durazo-Arvizu, Z. Li, Y. Liao, D. Mcgee, T. E. Prewitt, C. Sempos Dec 1999

Effect Of Smoking On The Body Mass Index-Mortality Relation: Empirical Evidence From 15 Studies, V. Hawthorne, V. Hawthorne, D. Kozarevic, N. Vojvodic, C. R. Gillis, D. Hole, C. Hart, T. Jorgensen, T. Thomsen, M. Davidson, U. Goldbourt, S. Yaari, G. Cao, R. Cooper, R. Durazo-Arvizu, Z. Li, Y. Liao, D. Mcgee, T. E. Prewitt, C. Sempos

Faculty Publications

The authors examined the impact of smoking status on the relation between body mass index (weight (kg)/height (m)2) and mortality across a group of 15 diverse observational studies. The studies included a heterogeneous sample of national samples, cohort studies with mortality follow-up, and clinical trials. Consideration of the data according to natural strata resulted in the formation of 42 analytic cohorts. The authors examined survival through the end of follow-up for each study, as influenced by body mass index, age, and current smoking status at baseline, using a proportional hazards model to describe the relation between body mass index and …


Simulation And Density Functional Study Of A Simple Membrane Separating Two Restricted Primitive Model Electrolytes, Richard L. Rowley, Dezso Boda, Douglas Henderson, Stefan Sokolowski Nov 1999

Simulation And Density Functional Study Of A Simple Membrane Separating Two Restricted Primitive Model Electrolytes, Richard L. Rowley, Dezso Boda, Douglas Henderson, Stefan Sokolowski

Faculty Publications

A simple membrane, supporting charge densities on its inner and outer surfaces, is considered. In addition to the electrostatic potential, the membrane interacts with the surrounding fluid by a short range van der Waals-like potential. The fluid beyond the outer surface is a three-component restricted primitive electrolyte consisting of two cations and one anion. The membrane is impermeable to one of the cations so that the fluid in the membrane and beyond the inner surface is a two-component restricted primitive electrolyte. We use Monte Carlo simulations and density functional theory to study the density profiles of the electrolyte and the …


Regulation Of Signal Transducers And Activators Of Transcription (Stats) By Effectors Of Adipogenesis: Coordinate Regulation Of Stats 1, 5a, And 5b With Peroxisome Proliferator-Activated Receptor-Γ And C/Aaat Enhancer Binding Protein-Α, William C. Stewart, Ron F. Morrison, Sherry L. Young, Jacqueline M. Stephens Nov 1999

Regulation Of Signal Transducers And Activators Of Transcription (Stats) By Effectors Of Adipogenesis: Coordinate Regulation Of Stats 1, 5a, And 5b With Peroxisome Proliferator-Activated Receptor-Γ And C/Aaat Enhancer Binding Protein-Α, William C. Stewart, Ron F. Morrison, Sherry L. Young, Jacqueline M. Stephens

Faculty Publications

We have recently demonstrated that three signal transducers and activators of transcription (STAT) family members are induced during adipocyte differentiation (Stephens et al., J. Biol. Chem. 271 (1996) 10441- 10444). Since STATs 1, 5A, and 5B are induced during adipocyte differentiation, we have examined the ability of these proteins to be regulated by components of the differentiation cocktail. In addition, we have examined the effects of potent effectors of differentiation on STAT protein expression during adipogenesis. A negative effector, tumor necrosis factor-α (TNFα), and a positive effector, a thiazolidinedione, were used in these experiments. Our results demonstrate that the expression …


Regulation Of The Dolichol Pathway In Human Fibroblasts By The Endoplasmic Reticulum Unfolded Protein Response, William T. Doerrler, Mark A. Lehrman Nov 1999

Regulation Of The Dolichol Pathway In Human Fibroblasts By The Endoplasmic Reticulum Unfolded Protein Response, William T. Doerrler, Mark A. Lehrman

Faculty Publications

Accumulation of unfolded proteins within the endoplasmic reticulum (ER) of eukaryotic cells triggers the unfolded protein response (UPR), which activates transcription of several genes encoding ER chaperones and folding enzymes. This study reports that conversion of dolichol-linked Man2-5GIcNAc2 intermediates into mature Glc3Man9GlcNAc2 oligosaccharides in primary human adult dermal fibroblasts is also stimulated by the UPR. This stimulation was not evident in several immortal cell lines and did not require a cytoplasmic stress response. Inhibition of dolichol-linked Glc3Man9GlcNAc2 synthesis by glucose deprivation could be counteracted by the UPR, improving the transfer of Glc3Man9GlcNAc2 to asparagine residues on nascent polypeptides. Glycosidic processing …