Digital Commons Network^™

Immune Genotypes, Immune Responses, And Survival In A Wild Bird Population, Martha J. Nelson-Flower, Leanne A. Grieves, Jane M. Reid, Ryan R. Germain, Savo Lazic, Sabrina S. Taylor, Elizabeth A. Macdougall-Shackleton, Peter Arcese

Faculty Publications

Individuals vary in their immune genotype, inbreeding coefficient f, immune responses, survival to adulthood, and adult longevity. However, whether immune genes predict survival or longevity, whether such relationships are mediated through immune responses, and how f affects immune genotype remain unclear. We use a wild song sparrow (Melospiza melodia) population in which survival to adulthood, adult longevity, and f were measured precisely, and in which immune responses have previously been assessed. We investigate four toll-like receptor (TLR) and the major histocompatibility complex (MHC) class IIB exon 2 genes. We test whether immune genes predict fitness (survival to adulthood or adult …

Molecular Research In Rice, Prasanta K. Subudhi

Faculty Publications

No abstract provided.

A Comparison Of Bat Calls Recorded By Two Acoustic Monitors, Jane M. Kunberger, Ashley M. Long

Faculty Publications

Recent advances in low-cost autonomous recording unit (ARU) technology have made large-scale bat monitoring projects more practical, but several key features of ARUs (e.g., microphone quality and triggering thresholds) can influence their ability to detect and record bats. As such, it is important to quantify and report variation in ARU performance as new recording systems become available. We used the automated classification software SonoBat to compare the numbers of call files, echolocation pulses, and species recorded by a commonly used, full-spectrum bat detector-the Song Meter SM4BAT-FS-and a less expensive, open-source ARU that can detect ultrasound-the AudioMoth. We deployed paired ARUs …

Exploring The Experiences Of Pregnant Women In The U.S. During The First Year Of The Covid-19 Pandemic, Courtney E. Williams, Dana Berkowitz, Heather M. Rackin

Faculty Publications

In this paper, we integrate the stress process model with symbolic interactionism to frame our analysis of interviews with 35 women who were pregnant and/or gave birth during the first year of the Covid-19 pandemic. We detail three stressors, highlight their variation, and discuss how they coped with these stressors. Women reported having to navigate contradictory information about the public health crisis, but Black participants simultaneously endured added strain from a heightened awareness of racialized violence. To cope with an overabundance of precarious and contradictory messages, some women sought out information (i.e., information gatherers), others eschewed information (i.e., information avoiders), …

8(Meso)-Pyridyl-Bodipys: Effects Of 2,6-Substitution With Electron-Withdrawing Nitro, Chloro, And Methoxycarbonyl Groups, Caroline Ndung’U, Petia Bobadova-Parvanova, Daniel J. Lamaster, Dylan Goliber, Frank R. Fronczek, Maria Da Graça H. Vicente

Faculty Publications

The introduction of electron-withdrawing groups on 8(meso)-pyridyl-BODIPYs tends to increase the fluorescence quantum yields of this type of compound due to the decrease in electronic charge density on the BODIPY core. A new series of 8(meso)-pyridyl-BODIPYs bearing a 2-, 3-, or 4-pyridyl group was synthesized and functionalized with nitro and chlorine groups at the 2,6-positions. The 2,6-methoxycarbonyl-8-pyridyl-BODIPYs analogs were also synthesized by condensation of 2,4-dimethyl-3-methoxycarbonyl-pyrrole with 2-, 3-, or 4-formylpyridine followed by oxidation and boron complexation. The structures and spectroscopic properties of the new series of 8(meso)-pyridyl-BODIPYs were investigated both experimentally and computationally. The BODIPYs bearing 2,6-methoxycarbonyl groups showed enhanced …

The Distribution Of Surface Soil Moisture Over Space And Time In Eastern Taylor Valley, Antarctica, Mark R. Salvatore, John E. Barrett, Laura E. Fackrell, Eric R. Sokol, Joseph S. Levy, Lily C. Kuentz, Michael N. Gooseff, Byron J. Adams, Sarah N. Power, J. Paul Knightly, Haley M. Matul, Brian Szutu, Peter T. Doran

Faculty Publications

Available soil moisture is thought to be the limiting factor for most ecosystem processes in the cold polar desert of the McMurdo Dry Valleys (MDVs) of Antarctica. Previous studies have shown that microfauna throughout the MDVs are capable of biological activity when sufficient soil moisture is available (~2–10% gravimetric water content), but few studies have attempted to quantify the distribution, abundance, and frequency of soil moisture on scales beyond that of traditional field work or local field investigations. In this study, we present our work to quantify the soil moisture content of soils throughout the Fryxell basin using multispectral satellite …

Effects Of Individual Strategies For Resource Access On Collaboratively Maintained Irrigation Infrastructure, Jordan L. Stern, Afreen Siddiqi, Paul N. Grogan

Faculty Publications

Built infrastructure for water and energy supply, transportation, and other such services underpins human well-being and socioeconomic development. A fundamental understanding of how infrastructure design and user strategies interact can guide important design decisions as well as policy formulation for ensuring long-term infrastructure viability in conjunction with improved individual user benefits. In this work, an agent based model (ABM) is developed to study this issue for the specific case of irrigation canals. Cooperatively maintained irrigation canals serve essential roles in sustaining agriculture-based economies in many regions. Canal system design can strongly affect benefits derived by distributed users, regional agricultural output, …

Active Learning Methodologies In A High Stakes Graduate Nursing Program, Nina Mclain, Mary Jane Collins, Lawanda Baskin

Faculty Publications

Active learning with student engagement has been demonstrated to improve knowledge retention and improve learning in graduate education. Nurse anesthesia education has traditionally been taught using lecture with slide presentations without considering student centered learning. Much attention has been given to active learning strategies to promote student engagement and content retention, yet little information exists regarding student preferences for in higher level graduate nursing courses. This mixed-methods study aimed to examine student learning preferences for seven different instructional methodologies; traditional lecture, a problem-based learning exercise, reading with workbook assignments, development of cognitive aids, game-based learning, practice questions, and a case …

Hierarchical, Porous Hydrogels Demonstrating Structurally Dependent Mechanical Properties, Elisabeth Lloyd, Rami Alhasan, Sujata Dhakal, Svetlana Morozova, Douglas R. Tree, Robert Hickey

Faculty Publications

While hierarchical ordering is a distinctive feature of natural tissues and is directly responsible for their diverse and unique properties, research efforts to synthesize biomaterials have primarily focused on using molecular-based approaches without considering multiscale structure. Here, we report a bottom-up self-assembly process to produce highly porous hydrogels that resemble natural tissues both structurally and mechanically. Randomly oriented, physically crosslinked nanostructured micelles form the walls of aligned, polymer-rich pore walls that surround water-rich cavities. Extremely soft elastic modulus (<  1 kPa), highly stretchability (greater than 12-times), strain-hardening, and completely reversible deformation result from the hierarchical structure. Independent control of nano and macroscales is realized through the combination of polymer macromolecular parameters and processing conditions, directly impacting the resulting phase behavior. Here, we demonstrate precise control of the material structure and structure orientation over many orders of magnitude (e.g., nm – µm), and reveal how the multiscale structure directly impacts mechanical properties.

A Hierarchical Cluster Approach Toward Understanding The Regional Variable In Country Conflict Modeling, Benjamin D. Leiby, Darryl K. Ahner

Faculty Publications

Purpose: This paper aims to examine how the regional variable in country conflict modeling affects forecast accuracy and identifies a methodology to further improve the predictions.

Design/methodology/approach: This paper uses statistical learning methods to both evaluate the quantity of data for clustering countries along with quantifying accuracy according to the number of clusters used.

Findings: This study demonstrates that increasing the number of clusters for modeling improves the ability to predict conflict as long as the models are robust.

Originality/value: This study investigates the quantity of clusters used in conflict modeling, while previous research assumes a specific quantity before …

Contrasting Responses Of Atlantic And Pacific Tropical Cyclone Activity To Atlantic Multidecadal Variability, Huanping Huang, William D. Collins, Christina M. Patricola, Yohan Ruprich-Robert, Paul A. Ullrich, Alexander J. Baker

Faculty Publications

This research assesses the influences of Atlantic Multidecadal Variability (AMV) on global tropical cyclones (TCs) using two large ensembles of idealized global climate model simulations with opposite signs of AMV forcings superimposed (i.e., AMV+ and AMV–). We first detect TCs and then compare TC activity by basin in the two AMV experiments. We find contrasting responses of Atlantic and Pacific TC frequency to the AMV anomalies. Compared to AMV–, AMV+ significantly increases TC frequency in the North Atlantic, including those making landfalls. The increase is explained by warmer sea surface temperature, higher relative humidity, increased relative vorticity, and weaker vertical …

Fate And Transport Of Per- And Polyfluoroalkyl Substances (Pfas) At Aqueous Film Forming Foam (Afff) Discharge Sites: A Review, Jeffery T. Mcgarr, Eric G. Mbonimpa, Drew C. Mcavoy, Mohamad R. Soltanian

Faculty Publications

Per- and polyfluorinated alkyl substances (PFAS) are an environmentally persistent group of chemicals that can pose an imminent threat to human health through groundwater and surface water contamination. In this review, we evaluate the subsurface behavior of a variety of PFAS chemicals with a focus on aqueous film forming foam (AFFF) discharge sites. AFFF is the primary PFAS contamination risk at sites such as airports and military bases due to use as a fire extinguisher. Understanding the fate and transport of PFAS in the subsurface environment is a multifaceted issue. This review focuses on the role of adsorbent, adsorbate, and …

The Coralhydro2k Database: A Global, Actively Curated Compilation Of Coral Δ18o And Sr/Ca Proxy Records Of Tropical Ocean Hydrology And Temperature For The Common Era, Rachel M. Walter, Hussein R. Sayani, Thomas Felis, Kim M. Cobb, Nerilie J. Abram, Ariella K. Arzey, Alyssa R. Atwood, Logan D. Brenner, Émilie P. Dassié, Kristine L. Delong, Bethany Ellis, Julien Emile-Geay, Matthew J. Fischer, Nathalie F. Goodkin, Jessica A. Hargreaves, K. Halimeda Kilbourne, Hedwig Krawczyk, Nicholas P. Mckay, Andrea L. Moore, Sujata A. Murty, Maria Rosabelle Ong, Riovie D. Ramos, Emma V. Reed, Dhrubajyoti Samanta, Sara C. Sanchez, Jens Zinke

Faculty Publications

The response of the hydrological cycle to anthropogenic climate change, especially across the tropical oceans, remains poorly understood due to the scarcity of long instrumental temperature and hydrological records. Massive shallow-water corals are ideally suited to reconstructing past oceanic variability as they are widely distributed across the tropics, rapidly deposit calcium carbonate skeletons that continuously record ambient environmental conditions, and can be sampled at monthly to annual resolution. Climate reconstructions based on corals primarily use the stable oxygen isotope composition (δ18O), which acts as a proxy for sea surface temperature (SST), and the oxygen isotope composition of seawater (δ18Osw), a …

Microbial Carbon Use Efficiency Promotes Global Soil Carbon Storage, Feng Tao, Yuanyuan Huang, Bruce A. Hungate, Stefano Manzoni, Serita D. Frey, Michael W. I. Schmidt, Markus Reichstein, Nuno Carvalhais, Philippe Ciais, Lifen Jiang, Johannes Lehmann, Ying-Ping Wang, Benjamin Z. Houlton, Bernhard Ahrens, Umakant Mishra, Gustaf Hugelius, Toby D. Hocking, Xingjie Lu, Zheng Shi, Kostiantyn Viatkin, Ronald Vargas, Yusuf Yigini, Christian Omuto, Ashish A. Malik, Guillermo Peralta, Rosa Cuevas-Corona, Luciano E. Di Paolo, Isabel Luotto, Cuijuan Liao, Yi-Shuang Liang, Vinisa S. Saynes, Xiaomeng Huang, Yiqi Luo

Faculty Publications

Soils store more carbon than other terrestrial ecosystems1,2. How soil organic carbon (SOC) forms and persists remains uncertain1,3, which makes it challenging to understand how it will respond to climatic change3,4. It has been suggested that soil microorganisms play an important role in SOC formation, preservation and loss5,6,7. Although microorganisms affect the accumulation and loss of soil organic matter through many pathways4,6,8,9,10,11, microbial carbon use efficiency (CUE) is an integrative metric that can capture the balance of these processes12,13. Although CUE has the potential to act as a predictor of variation in SOC storage, the role of CUE in SOC …

A Deeper Understanding Of Noise Effects On Cetaceans, Jason N. Bruck

Faculty Publications

Recent research with cetaceans under human care is illuminating just how dolphins are affected by human-made noise both in terms of their ability to cooperate as well as their ability to habituate to such noise. This research is providing granular detail to regulators assessing the problems associated with anthropogenic effects and is highlighting a role for behavior/cognition research in conservation.

Nucleotide-Driven Molecular Sensing Of Monkeypox Virus Through Hierarchical Self-Assembly Of 2d Hafnium Disulfide Nanoplatelets And Gold Nanospheres, Parikshit Moitra, Maria Iftesum, David Skrodzki, Priyanka Paul, Elnaz Sheikh, Jennifer Lynn Gray, Ketan Dighe, Zach Sheffield, Manas Ranjan Gartia, Dipanjan Pan

Faculty Publications

Liquid interfaces facilitate the organization of nanometer-scale biomaterials with plasmonic properties suitable for molecular diagnostics. Using hierarchical assemblage of 2D hafnium disulfide nanoplatelets and zero-dimensional spherical gold nanoparticles, the design of a multifunctional material is reported. When the target analyte is present, the nanocomposites’ self-assembling pattern changes, altering their plasmonic response. Using monkeypox virus (MPXV) as an example, the findings reveal that adding genomic DNA to the nanocomposite surface increases the agglomeration between gold nanoparticles and decreases the π-stacking distance between hafnium disulfide nanoplatelets. Further, this self-assembled nanomaterial is found to have minimal cross-reactivity toward other pathogens and a limit …

Jurisdictional Conflicts In Adult Guardianship, David M. English

Faculty Publications

The case of Britney Spears has shined a spotlight on guardianship, a subject area in which there has been increasing interest in recent years. The events surrounding Ms. Spears s case all occurred in a single jurisdiction, California. But with Americas increasingly mobile population, an individual for whom a guardianship is sought may have contacts with multiple states and, in some cases, foreign countries. Furthermore, following the appointment of a guardian, the guardian or individual subject to guardianship may move to another jurisdiction; it may become necessary to transfer the guardianship proceeding to another jurisdiction or seek ratification of a …

Bayesian Order Constrained Adaptive Design For Phase Ii Clinical Trials Evaluating Subgroup-Specific Treatment Effect, Mu Shan, Beibei Guo, Hao Liu, Qian Li, Yong Zang

Faculty Publications

The “one-size-fits-all’’ paradigm is inappropriate for phase II clinical trials evaluating biotherapies, which are often expected to have substantial heterogeneous treatment effects among different subgroups defined by biomarker. For these biotherapies, the objective of phase II clinical trials is often to evaluate subgroup-specific treatment effects. In this article, we propose a simple yet efficient Bayesian adaptive phase II biomarker-guided design, referred to as the Bayesian-order constrained adaptive design, to detect the subgroup-specific treatment effects of biotherapies. The Bayesian order constrained adaptive design combines the features of the enrichment design and sequential design. It starts with a “all-comers” stage, and subsequently …

Mathematics Library News, Aaron Lercher

Faculty Publications

Mathematics Library News is an LSU Libraries newsletter for members of the Mathematics and Experimental Statistics Departments, published roughly once each semester.

Niche Specialization And Community Niche Space Increase With Species Richness In Filter-Feeder Assemblages, Irene Sánchez González, Garrett W. Hopper, Jamie R. Bucholz, Megan E. Kubala, Jeffrey D. Lozier, Carla L. Atkinson

Faculty Publications

Ecological theory posits that higher species richness should be associated with greater exploitation of resources and niche packing resulting from either increasing species niche overlap or specialization of species' niches. Research evaluating niche theory in animals tends to focus on organisms among functional feeding guilds, while resource partitioning might be more critical within functional groups. Freshwater mussels (Family: Unionidae) are a diverse and imperiled group of animals that are ideal models to test niche occupancy due to their functional similarity as filter-feeders and their occurrence in spatially and temporally stable multispecies aggregations. We evaluated the relationship between species richness and …

Latino Paradox Or Black Exception? Race, Ethnicity, And Crime In The 21st Century, Edward S. Shihadeh, Raymond E. Barranco

Faculty Publications

George Floyd’s murder by a Minnesota police officer sparked outrage, protests, and a re-evaluation of racial inequities in America. Within criminology, we argue, that re-evaluation should include the Latino Paradox, the idea that Latino communities are an exception—a paradox—in that, while they face economic deprivation, they also possess a magical something that makes them resistant to social problems like crime. Unfortunately, this compels the more delicate question; what is the deficiency in Black communities that makes them so vulnerable to crime? However, as we argue here, the Latino Paradox forces a false comparison. Its assumptions with respect to crime are …

Amazonian Birds In More Dynamic Habitats Have Less Population Genetic Structure And Higher Gene Flow, Oscar Johnson, Camila C. Ribas, Alexandre Aleixo, Luciano N. Naka, Michael G. Harvey, Robb T. Brumfield

Faculty Publications

Understanding the factors that govern variation in genetic structure across species is key to the study of speciation and population genetics. Genetic structure has been linked to several aspects of life history, such as foraging strategy, habitat association, migration distance, and dispersal ability, all of which might influence dispersal and gene flow. Comparative studies of population genetic data from species with differing life histories provide opportunities to tease apart the role of dispersal in shaping gene flow and population genetic structure. Here, we examine population genetic data from sets of bird species specialized on a series of Amazonian habitat types …

Handling And Restraint Induce A Significant Increase In Plasma Corticosterone In Hispaniolan Amazon Parrots (Amazona Ventralis), Shelby N. Parks, Thomas N. Tully, Aspen L. Settle, Christine R. Lattin

Faculty Publications

OBJECTIVE: To measure baseline plasma corticosterone levels in Hispaniolan Amazon parrots (Amazona ventralis) and assess the effects of handling and restraint on corticosterone levels over 1 hour, reflective of what parrots might experience during veterinary care. ANIMALS: 10 male and 12 female Hispaniolan Amazon parrots. PROCEDURES: Each parrot was removed from its cage and wrapped in a towel for restraint similar to that performed in a clinical setting. An initial baseline blood sample was collected in < 3 minutes upon entrance into the parrot room, after which blood samples were taken every 15 minutes for 1 hour (a total of 5 blood samples). An enzyme-linked immunoassay was validated for Hispaniolan Amazon parrots and used to determine concentrations of plasma corticosterone. RESULTS: On average, parrots showed a significant increase in corticosterone between baseline samples and all subsequent postrestraint time points (average baseline corticosterone ± SD: 0.51 ± 0.65 ng/mL). Females, on average, displayed significantly higher corticosterone levels than males after 30, 45, and 60 minutes of restraint (P = .016, P = .0099, and P = .015, respectively). Birds with feather-destructive behavior did not have significantly higher corticosterone levels than birds without the condition (P = .38). CLINICAL RELEVANCE: Understanding the physiological stress response in companion psittacine birds during routine handling will allow clinicians to better evaluate how this may affect the patient's condition and diagnostic test results. Assessing how corticosterone correlates to behavioral conditions such as feather-destructive behavior will provide clinicians with the potential to develop treatment options.

Predictors And Barriers To Vaccination Among Older Syrian Refugees In Lebanon: A Cross-Sectional Analysis Of A Multi-Wave Longitudinal Study, Berthe Abi Zeid, Tanya El Khoury, Hala Ghattas Ph.D., Marwan F. Alawieh, Zeinab Ramadan, Sirine Anouti, Sawsan Abdulrahim, Stephen J. Mccall

Faculty Publications

Background:

Vaccination is important to prevent morbidity and mortality due to COVID-19 among older Syrian refugees. We aimed to elucidate the predictors of COVID-19 vaccine uptake among Syrian refugees aged 50 years or older in Lebanon and to understand their main reasons for not receiving the vaccine.

Methods:

This was a cross-sectional analysis of a five-wave longitudinal study, conducted through telephone interviews between Sept 22, 2020, and March 14, 2022, in Lebanon. For this analysis, data were extracted from wave 3 (Jan 21–April 23, 2021), which included a question on vaccine safety and on whether participants intended to receive the …

Covid-19 Challenges, Responses, And Resilience Among Rural Black Women: A Study Protocol, Fanghui Shi, Jiajia Zhang Ph.D., Chengbo Zeng, Xiaowen Sun, Zhenlong Li, Xueying Yang, Sharon Weissman, Bankole Olatosi Ph.D., Xiaoming Li Ph.D.

Faculty Publications

Background

Timely linkage to care (LTC) is key in the HIV care continuum, as it enables people newly diagnosed with HIV (PNWH) to benefit from HIV treatment at the earliest stage. Previous studies have found LTC disparities by individual factors, but data are limited beyond the individual level, especially at the county level. This study examined the temporal and geographic variations of county-level LTC status across 46 counties in South Carolina (SC) from 2010 to 2018 and the association of county-level characteristics with LTC status.

Methods

All adults newly diagnosed with HIV from 2010 to 2018 in SC were included …

Decision Support Issues In Automated Driving Systems, William N. Caballero, David Ríos Insua, David Banks

Faculty Publications

Machine learning and computational processing have advanced such that automated driving systems (ADSs) are no longer a distant reality. Many automobile manufacturers have developed prototypes; however, there exist numerous decision support issues requiring resolution to ensure mass ADS adoption. In the coming decades, it is likely that production ADSs will only be partially autonomous. Such ADSs operate within predetermined conditions and require driver intervention when they are violated. Since forecasts of their 20-year market penetration are relatively low, ADSs will likely operate in heterogeneous traffic characterized by vehicles of varying autonomy levels. Under these conditions, effective decision support must consider …

Environment Knowledge-Driven Generic Models To Detect Coughs From Audio Recordings, Sudip Vhaduri, Sayanton V. Dibbo, Yugyeong Kim

Faculty Publications

Goal: Millions of people are dying due to res- piratory diseases, such as COVID-19 and asthma, which are often characterized by some common symptoms, including coughing. Therefore, objective reporting of cough symp- toms utilizing environment-adaptive machine-learning models with microphone sensing can directly contribute to respiratory disease diagnosis and patient care. Methods: In this work, we present three generic modeling approaches – unguided, semi-guided, and guided approaches consid- ering three potential scenarios, i.e., when a user has no prior knowledge, some knowledge, and detailed knowledge about the environments, respectively. Results: From detailed analysis with three datasets, we find that guided models …

Caveat Emptor: Scan Quality Of Elsevier’S Digital Backfile Pdf Collection, Gregory M. Nelson, Paul Kj Robbins, Dennis L. Eggett

Faculty Publications

Scans of journal articles originally published in print, otherwise known as digital journal backfiles, benefit library patrons by providing near instantaneous access to important older information and full-text searchability. Digital backfiles can serve as a reliable surrogate for their corresponding print journals which could be removed from the library, freeing up space for other patron services. Both benefits are realized when the scanned articles are of sufficient clarity to replace the print versions. Several studies have analyzed small and subject-narrow sections of Elsevier’s digital backfile. This article contains a scan-quality analysis from 1578 journals that contain nearly four million articles …

Kinetic And Chemical Effects Of Clays And Other Fillers In The Preparation Of Epoxy-Vinyl Ether Composites Using Radical-Induced Cationic Frontal Polymerization, Brecklyn R. Groce, Emma E. Lane, Daniel P. Gary, Douglas T. Ngo, Dylan T. Ngo, Fahima Shaon, Jorge A. Belgodere, John A. Pojman

Faculty Publications

Addition of fillers to formulations can generate composites with improved mechanical properties and lower the overall cost through a reduction of chemicals needed. In this study, fillers were added to resin systems consisting of epoxies and vinyl ethers that frontally polymerized through a radical-induced cationic frontal polymerization (RICFP) mechanism. Different clays, along with inert fumed silica, were added to increase the viscosity and reduce the convection, results of which did not follow many trends present in free-radical frontal polymerization. The clays were found to reduce the front velocity of RICFP systems overall compared to systems with only fumed silica. It …

Injectable Antioxidant And Oxygen-Releasing Lignin Composites To Promote Wound Healing, Swathi Balaji, Walker D. Short, Benjamin W. Padon, Jorge A. Belgodere, Sarah E. Jimenez, Naresh T. Deoli, Anna C. Guidry, Justin C. Green, Tanuj J. Prajapati, Fayiz Farouk, Aditya Kaul, Dongwan Son, Olivia S. Jung, Carlos E. Astete, Myungwoong Kim, Jangwook P. Jung

Faculty Publications

The application of engineered biomaterials for wound healing has been pursued since the beginning of tissue engineering. Here, we attempt to apply functionalized lignin to confer antioxidation to the extracellular microenvironments of wounds and to deliver oxygen from the dissociation of calcium peroxide for enhanced vascularization and healing responses without eliciting inflammatory responses. Elemental analysis showed 17 times higher quantity of calcium in the oxygen-releasing nanoparticles. Lignin composites including the oxygen-generating nanoparticles released around 700 ppm oxygen per day at least for 7 days. By modulating the concentration of the methacrylated gelatin, we were able to maintain the injectability of …