Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

Faculty Publications

Discipline
Institution
Keyword
Publication Year
File Type

Articles 4831 - 4860 of 10802

Full-Text Articles in Entire DC Network

Stability And Controlled Release Of Lutein Loaded In Zein Nanoparticles With And Without Lecithin And Pluronic F127 Surfactants, Thanida Chuacharoen, Cristina M. Sabliov Aug 2016

Stability And Controlled Release Of Lutein Loaded In Zein Nanoparticles With And Without Lecithin And Pluronic F127 Surfactants, Thanida Chuacharoen, Cristina M. Sabliov

Faculty Publications

The ability of zein nanoparticles, made with and without surfactants, to protect lutein from oxidation and to control its release was studied under various conditions. A combination of lecithin and pluronic F127 as surfactants was used to promote physicochemical stability of the nanoparticles and entrapped bioactives. Surfactant use resulted in an increased size, improved polydispersity index, decreased zeta potential, and improved entrapment efficiency. A two-phase lutein release profile was observed in phosphate-buffered saline (PBS) that consisted of an initial-burst release at 24 h, decreased in the presence of surfactants, followed by a gradual zero-order release profile for both systems. Lutein …

Go to article

Developmental Functions Of Mir156-Regulated Squamosa Promoter Binding Protein-Like (Spl) Genes In Arabidopsis Thaliana, Mingli Xu, Tieqiang Hu, Jianfei Zhao, Mee-Yeon Park, Keith W. Earley, Gang Wu, Li Yang, R. Scott Poethig Aug 2016

Developmental Functions Of Mir156-Regulated Squamosa Promoter Binding Protein-Like (Spl) Genes In Arabidopsis Thaliana, Mingli Xu, Tieqiang Hu, Jianfei Zhao, Mee-Yeon Park, Keith W. Earley, Gang Wu, Li Yang, R. Scott Poethig

Faculty Publications

Correct developmental timing is essential for plant fitness and reproductive success. Two important transitions in shoot development—the juvenile-to-adult vegetative transition and the vegetative-to-reproductive transition—are mediated by a group of genes targeted by miR156, SQUAMOSA PROMOTER BINDING PROTEIN (SBP) genes. To determine the developmental functions of these genes in Arabidopsis thaliana, we characterized their expression patterns, and their gain-of-function and loss-of-function phenotypes. Our results reveal that SBP-LIKE (SPL) genes in Arabidopsis can be divided into three functionally distinct groups: 1) SPL2, SPL9, SPL10, SPL11, SPL13 and SPL15 contribute to both the juvenile-to-adult vegetative transition …

Go to article

Five Years Later: An Update On The Status Of Collections Of Endemic Gulf Of Mexico Fishes Put At Risk By The 2010 Oil Spill, Prosanta Chakrabarty, Glynn A. O'Neill, Brannon Hardy, Brandon Ballengee Aug 2016

Five Years Later: An Update On The Status Of Collections Of Endemic Gulf Of Mexico Fishes Put At Risk By The 2010 Oil Spill, Prosanta Chakrabarty, Glynn A. O'Neill, Brannon Hardy, Brandon Ballengee

Faculty Publications

© Chakrabarty P et al. Background The 2010 Gulf of Mexico Oil Spill took place over 180,000 square kilometers during a 12- week period over five years ago; however, this event continues to influence the development and distribution of organisms in and around the region of the disaster. Here we examine fish species that may have been most affected by noting their past distribution in the region of the spill and examining data of known collecting events over the last 10 years (five years prior to the spill, five years post spill). New information We found that more than half …

Go to article

Loss Of Oncostatin M Signaling In Adipocytes Induces Insulin Resistance And Adipose Tissue Inflammation In Vivo∗, Carrie M. Elks, Peng Zha, Ryan W. Grant, Hardy Hang, Jennifer L. Bailey, David H. Burk, Margaret A. Mcnulty, Randall L. Mynatt, Jacqueline M. Stephens Aug 2016

Loss Of Oncostatin M Signaling In Adipocytes Induces Insulin Resistance And Adipose Tissue Inflammation In Vivo∗, Carrie M. Elks, Peng Zha, Ryan W. Grant, Hardy Hang, Jennifer L. Bailey, David H. Burk, Margaret A. Mcnulty, Randall L. Mynatt, Jacqueline M. Stephens

Faculty Publications

© 2016 by The American Society for Biochemistry and Molecular Biology, Inc. Oncostatin M (OSM) is a multifunctional gp130 cytokine. Although OSM is produced in adipose tissue, it is not produced by adipocytes. OSM expression is significantly induced in adipose tissue from obese mice and humans. The OSM-specific receptor, OSM receptor ô (OSMR), is expressed in adipocytes, but its function remains largely unknown. To better understand the effects of OSM in adipose tissue, we knocked down Osmr expression in adipocytes in vitro using siRNA. In vivo, we generated a mouse line lacking Osmr in adiponectin-expressing cells (OSMRFKO mice). The effects …

Go to article

Eleven Years Of Crop Diversification Alters Decomposition Dynamics Of Litter Mixtures Incubated With Soil, M. D. Mcdaniel, A. Stuart Grandy, Lisa K. Tiemann, Michael N. Weintraub Aug 2016

Eleven Years Of Crop Diversification Alters Decomposition Dynamics Of Litter Mixtures Incubated With Soil, M. D. Mcdaniel, A. Stuart Grandy, Lisa K. Tiemann, Michael N. Weintraub

Faculty Publications

Agricultural crop rotations have been shown to increase soil carbon (C), nitrogen (N), and microbial biomass. The mechanisms behind these increases remain unclear, but may be linked to the diversity of crop residue inputs to soil organic matter (SOM). We used a residue mixture incubation to examine how variation in long-term diversity of plant communities in agroecosystems influences decomposition of residue mixtures, thus providing a comparison of the effects of plant diversification on decomposition in the long term (via crop rotation) and short term (via residue mixtures). Three crop residue mixtures, ranging in diversity from two to four species, were …

Go to article

Structural Polymorphism Of Alzheimer's Β-Amyloid Fibrils As Controlled By An E22 Switch: A Solid-State Nmr Study, Matthew R. Elkins, Tuo Wang, Mimi Nick, Hyunil Jo, Thomas Lemmin, Stanley B. Prusiner, William F. Degrado, Jan Stöhr, Mei Hong Aug 2016

Structural Polymorphism Of Alzheimer's Β-Amyloid Fibrils As Controlled By An E22 Switch: A Solid-State Nmr Study, Matthew R. Elkins, Tuo Wang, Mimi Nick, Hyunil Jo, Thomas Lemmin, Stanley B. Prusiner, William F. Degrado, Jan Stöhr, Mei Hong

Faculty Publications

© 2016 American Chemical Society. The amyloid-β (Aβ) peptide of Alzheimer's disease (AD) forms polymorphic fibrils on the micrometer and molecular scales. Various fibril growth conditions have been identified to cause polymorphism, but the intrinsic amino acid sequence basis for this polymorphism has been unclear. Several single-site mutations in the center of the Aβ sequence cause different disease phenotypes and fibrillization properties. The E22G (Arctic) mutant is found in familial AD and forms protofibrils more rapidly than wild-type Aβ. Here, we use solid-state NMR spectroscopy to investigate the structure, dynamics, hydration and morphology of Arctic E22G Aβ40 fibrils. 13C, 15N-labeled …

Go to article

Copper(Ii) Ions Increase Plasminogen Activator Inhibitor Type 1 Dynamics In Key Structural Regions That Govern Stability, Joel C. Bucci, Morten Beck Trelle, Carlee S. Mcclintock, Tihami Qureshi, Thomas J.D. Jørgensen, Cynthia B. Peterson Aug 2016

Copper(Ii) Ions Increase Plasminogen Activator Inhibitor Type 1 Dynamics In Key Structural Regions That Govern Stability, Joel C. Bucci, Morten Beck Trelle, Carlee S. Mcclintock, Tihami Qureshi, Thomas J.D. Jørgensen, Cynthia B. Peterson

Faculty Publications

© 2016 American Chemical Society. Plasminogen activator inhibitor type 1 (PAI-1) regulates the fibrinolysis pathway by inhibiting the protease activity of plasminogen activators. PAI-1 works in concert with vitronectin (VN), an extracellular protein that aids in localization of active PAI-1 to tissues. The Peterson laboratory demonstrated that Cu(II) and other transition metals modulate the stability of PAI-1, exhibiting effects that are dependent on the presence or absence of the somatomedin B (SMB) domain of VN. The study presented here dissects the changes in molecular dynamics underlying the destabilizing effects of Cu(II) on PAI-1. We utilize backbone amide hydrogen/deuterium exchange monitored …

Go to article

Ammonia Binding In The Second Coordination Sphere Of The Oxygen-Evolving Complex Of Photosystem Ii, David J. Vinyard, Mikhail Askerka, Richard J. Debus, Victor S. Batista, Gary W. Brudvig Aug 2016

Ammonia Binding In The Second Coordination Sphere Of The Oxygen-Evolving Complex Of Photosystem Ii, David J. Vinyard, Mikhail Askerka, Richard J. Debus, Victor S. Batista, Gary W. Brudvig

Faculty Publications

© 2016 American Chemical Society. Ammonia binds to two sites in the oxygen-evolving complex (OEC) of Photosystem II (PSII). The first is as a terminal ligand to Mn in the S2 state, and the second is at a site outside the OEC that is competitive with chloride. Binding of ammonia in this latter secondary site results in the S2 state S = 5/2 spin isomer being favored over the S = 1/2 spin isomer. Using electron paramagnetic resonance spectroscopy, we find that ammonia binds to the secondary site in wild-type Synechocystis sp. PCC 6803 PSII, but not in D2-K317A mutated …

Go to article

Modeling Pco2 Variability In The Gulf Of Mexico, Zuo Xue, Ruoying He, Katja Fennel, Wei Jun Cai, Steven Lohrenz, Wei Jen Huang, Hanqin Tian, Wei Ren, Zhengchen Zang Aug 2016

Modeling Pco2 Variability In The Gulf Of Mexico, Zuo Xue, Ruoying He, Katja Fennel, Wei Jun Cai, Steven Lohrenz, Wei Jen Huang, Hanqin Tian, Wei Ren, Zhengchen Zang

Faculty Publications

A three-dimensional coupled physical-biogeochemical model was used to simulate and examine temporal and spatial variability of sea surface pCO2 in the Gulf of Mexico (GoM). The model was driven by realistic atmospheric forcing, open boundary conditions from a dataassimilative global ocean circulation model, and observed freshwater and terrestrial nutrient and carbon input from major rivers. A 7-year model hindcast (2004-2010) was performed and validated against ship measurements. Model results revealed clear seasonality in surface pCO2 and were used to estimate carbon budgets in the Gulf. Based on the average of model simulations, the GoM was a net CO2 sink with …

Go to article

Dissolved Organic Carbon Uptake In Streams: A Review And Assessment Of Reach‐Scale Measurements, Madeleine M. Mineau, Wilfred M. Wollheim, Ishi Buffam, Stuart E. G. Findlay, Robert O. Hall Jr., Erin R. Hotchkiss, Lauren E. Koenig, William H. Mcdowell, Thomas B. Parr Aug 2016

Dissolved Organic Carbon Uptake In Streams: A Review And Assessment Of Reach‐Scale Measurements, Madeleine M. Mineau, Wilfred M. Wollheim, Ishi Buffam, Stuart E. G. Findlay, Robert O. Hall Jr., Erin R. Hotchkiss, Lauren E. Koenig, William H. Mcdowell, Thomas B. Parr

Faculty Publications

Quantifying the role that freshwater ecosystems play in the global carbon cycle requires accurate measurement and scaling of dissolved organic carbon (DOC) removal in river networks. We reviewed reach‐scale measurements of DOC uptake from experimental additions of simple organic compounds or leachates to inform development of aquatic DOC models that operate at the river network, regional, or continental scale. Median DOC uptake velocity (vf) across all measurements was 2.28 mm min−1. Measurements using simple compound additions resulted in faster vf (2.94 mm min−1) than additions of leachates (1.11 mm min−1). We also reviewed published data of DOC bioavailability for ambient …

Go to article

Effects Of Model Physics On Hypoxia Simulations For The Northern Gulf Of Mexico: A Model Intercomparison, Katja Fennel, Arnaud Laurent, Robert Hetland, Dubravko Justić, Dong S. Ko, John Lehrter, Michael Murrell, Lixia Wang, Liuqian Yu, Wenxia Zhang Aug 2016

Effects Of Model Physics On Hypoxia Simulations For The Northern Gulf Of Mexico: A Model Intercomparison, Katja Fennel, Arnaud Laurent, Robert Hetland, Dubravko Justić, Dong S. Ko, John Lehrter, Michael Murrell, Lixia Wang, Liuqian Yu, Wenxia Zhang

Faculty Publications

A large hypoxic zone forms every summer on the Texas-Louisiana Shelf in the northern Gulf of Mexico due to nutrient and freshwater inputs from the Mississippi/Atchafalaya River System. Efforts are underway to reduce the extent of hypoxic conditions through reductions in river nutrient inputs, but the response of hypoxia to such nutrient load reductions is difficult to predict because biological responses are confounded by variability in physical processes. The objective of this study is to identify the major physical model aspects that matter for hypoxia simulation and prediction. In order to do so, we compare three different circulation models (ROMS, …

Go to article

In Vitro Evaluation Of Thermal Frontally Polymerized Thiol-Ene Composites As Bone Augments, Nicholas P. Totaro, Zachari D. Murphy, Abigail E. Burcham, Connor T. King, Thomas F. Scherr, Christopher O. Bounds, Vinod Dasa, John A. Pojman, Daniel J. Hayes Aug 2016

In Vitro Evaluation Of Thermal Frontally Polymerized Thiol-Ene Composites As Bone Augments, Nicholas P. Totaro, Zachari D. Murphy, Abigail E. Burcham, Connor T. King, Thomas F. Scherr, Christopher O. Bounds, Vinod Dasa, John A. Pojman, Daniel J. Hayes

Faculty Publications

© 2015 Wiley Periodicals, Inc. Because of the large number of total knee replacement (TKR) surgeries conducted per year, and with projections of increased demand to almost a million primary TKR surgeries per year by 2030 in the United States alone, there is a need to discover more efficient working materials as alternatives to current bone cements. There is a need for surgeons and hospitals to become more efficient and better control over the operative environment. One area of inefficiency is the cement steps during TKR. Currently the surgeon has very little control over cement polymerization. This leads to an …

Go to article

A Fungal Endophyte Helps Plants To Tolerate Root Herbivory Through Changes In Gibberellin And Jasmonate Signaling, Marco Cosme, Jing Lu, Matthias Erb, Michael Joseph Stout, Philipp Franken, Susanne Wurst Aug 2016

A Fungal Endophyte Helps Plants To Tolerate Root Herbivory Through Changes In Gibberellin And Jasmonate Signaling, Marco Cosme, Jing Lu, Matthias Erb, Michael Joseph Stout, Philipp Franken, Susanne Wurst

Faculty Publications

© 2016 The Authors. New Phytologist © 2016 New Phytologist Trust. Plant–microbe mutualisms can improve plant defense, but the impact of root endophytes on below-ground herbivore interactions remains unknown. We investigated the effects of the root endophyte Piriformospora indica on interactions between rice (Oryza sativa) plants and its root herbivore rice water weevil (RWW; Lissorhoptrus oryzophilus), and how plant jasmonic acid (JA) and GA regulate this tripartite interaction. Glasshouse experiments with wild-type rice and coi1-18 and Eui1-OX mutants combined with nutrient, jasmonate and gene expression analyses were used to test: whether RWW adult herbivory above ground influences subsequent damage caused …

Go to article

Maternal Obesity Epigenetically Alters Visceral Fat Progenitor Cell Properties In Male Offspring Mice, Xingwei Liang, Qiyuan Yang, Xing Fu, Carl J. Rogers, Bo Wang, Hong Pan, Mei Jun Zhu, Peter W. Nathanielsz, Min Du Aug 2016

Maternal Obesity Epigenetically Alters Visceral Fat Progenitor Cell Properties In Male Offspring Mice, Xingwei Liang, Qiyuan Yang, Xing Fu, Carl J. Rogers, Bo Wang, Hong Pan, Mei Jun Zhu, Peter W. Nathanielsz, Min Du

Faculty Publications

© 2016 The Authors. The Journal of Physiology © 2016 The Physiological Society Key points: Maternal obesity reduces adipogenic progenitor density in offspring adipose tissue. The ability of adipose tissue expansion in the offspring of obese mothers is limited and is associated with metabolic dysfunction of adipose tissue when challenged with a high-fat diet. Maternal obesity induces DNA demethylation in the promoter of zinc finger protein 423, which renders progenitor cells with a high adipogenic capacity. Maternal obesity demonstrates long-term effects on the adipogenic capacity of progenitor cells in offspring adipose tissue, demonstrating a developmental programming effect. Abstract: Maternal obesity …

Go to article

A Framework For Implementing Course-Based Undergraduate Research Experiences (Cures) In Freshman Biology Labs, Arundhati Bakshi, Lorelei E. Patrick, E. William Wischusen Aug 2016

A Framework For Implementing Course-Based Undergraduate Research Experiences (Cures) In Freshman Biology Labs, Arundhati Bakshi, Lorelei E. Patrick, E. William Wischusen

Faculty Publications

© 2016 National Association of Biology Teachers. All rights reserved. There have been many calls to make research experiences available to more undergraduate students. One way to do this is to provide course-based undergraduate research experiences (CUREs), but providing these on a scale large enough to accommodate many students can be a daunting undertaking. Indeed, other researchers have identified time to develop materials and course size as significant barriers to widespread implementation of CUREs. Based on our own experiences implementing CUREs at a large research university, we present a flexible framework that we have adapted to multiple research projects, share …

Go to article

Pyrogenic Fuels Produced By Savanna Trees Can Engineer Humid Savannas, William J. Platt, Darin P. Ellair, Jean M. Huffman, Stephen E. Potts, Brian Beckage Aug 2016

Pyrogenic Fuels Produced By Savanna Trees Can Engineer Humid Savannas, William J. Platt, Darin P. Ellair, Jean M. Huffman, Stephen E. Potts, Brian Beckage

Faculty Publications

© 2016 by the Ecological Society of America. Natural fires ignited by lightning strikes following droughts frequently are posited as the ecological mechanism maintaining discontinuous tree cover and grass-dominated ground layers in savannas. Such fires, however, may not reliably maintain humid savannas. We propose that savanna trees producing pyrogenic shed leaves might engineer fire characteristics, affecting ground-layer plants in ways that maintain humid savannas. We explored our hypothesis in a high-rainfall, frequently burned pine savanna in which the dominant tree, longleaf pine (Pinus palustris), produces resinous needles that become highly flammable when shed and dried. We postulated that pyrogenic needles …

Go to article

Efficacy Of Entomopathogenic Nematodes And Sprayable Polymer Gel Against Crucifer Flea Beetle (Coleoptera: Chrysomelidae) On Canola, Frank B. Antwi, Gadi V.P. Reddy Aug 2016

Efficacy Of Entomopathogenic Nematodes And Sprayable Polymer Gel Against Crucifer Flea Beetle (Coleoptera: Chrysomelidae) On Canola, Frank B. Antwi, Gadi V.P. Reddy

Faculty Publications

The crucifer flea beetle, Phyllotreta cruciferae (Goeze), is a key pest of canola (Brassica napus L.) in the northern Great Plains of North America. The efficacies of entomopathogenic nematodes (Steinernema spp. and Heterorhabditis spp.), a sprayable polymer gel, and a combination of both were assessed on canola for flea beetle management. Plots were treated soon after colonization by adult flea beetles, when canola was in the cotyledon to one-leaf stage. Ten plants along a 3.6-m section of row were selected and rated at pre-treatment and 7 and 14 d post treatment using the damage-rating scheme advanced by the European Plant …

Go to article

Association Between 25-Hydroxyvitamin D And Intact Parathyroid Hormone Levels Across Latitude Among Adults With African Ancestry, Holly Kramer, Pauline Camacho, John Aloia, Amy Luke, Pascal Bovet, Jacob Plange Rhule, Terrence Forrester, Vickie Lambert, Regina Harders, Lara Dugas, Richard Cooper, Ramon Durazo-Arvizu Aug 2016

Association Between 25-Hydroxyvitamin D And Intact Parathyroid Hormone Levels Across Latitude Among Adults With African Ancestry, Holly Kramer, Pauline Camacho, John Aloia, Amy Luke, Pascal Bovet, Jacob Plange Rhule, Terrence Forrester, Vickie Lambert, Regina Harders, Lara Dugas, Richard Cooper, Ramon Durazo-Arvizu

Faculty Publications

Objective: To compare levels of 25-hydroxyvitamin D (25OHD) associated with a plateauing of intact parathyroid (iPTH) across latitudes among adults with African ancestry. Methods: This study included approximately 500 adults of African ancestry ages 25 to 45 years living in 4 sites: Chicago, Illinois (41°N), Jamaica (17°N), Ghana (6°N), and South Africa (34°S). Multivariate linear regression models, a nonlinear logistic growth curve model, and piecewise linear models with a single knot were fitted to estimate the 25OHD level associated with a plateauing of iPTH with adjustment for covariates. Goodness of fit was compared using computer intensive permutation tests. Results: Mean …

Go to article

Spatiotemporal Distributions Of Sr And Ba Along An Estuarine River With A Large Salinity Gradient To The Gulf Of Mexico, Songjie He, Y. Jun Xu Aug 2016

Spatiotemporal Distributions Of Sr And Ba Along An Estuarine River With A Large Salinity Gradient To The Gulf Of Mexico, Songjie He, Y. Jun Xu

Faculty Publications

Strontium and barium to calcium ratios are often used as proxies for tracking animal movement across salinity gradients. Many estuarine rivers face saltwater intrusion due to sea level rise, potentially causing changes in mobility and distribution of these metals upstream. From May 2013 to August 2015, monthly water samples were collected and in-situ measurements were performed at six sites along an estuary strongly affected by saltwater intrusion, the Calcasieu River, with salinity ranging from 0.02 to 29.50 Parts Per Thousand (ppt). Results showed that the total Sr concentration and the Sr/Ca ratio both increased significantly with increasing salinity. The average …

Go to article

Progress And Prospects Of Reactive Oxygen Species In Metal Carcinogenesis, Lei Wang, James T.F. Wise, Zhuo Zhang, Xianglin Shi Aug 2016

Progress And Prospects Of Reactive Oxygen Species In Metal Carcinogenesis, Lei Wang, James T.F. Wise, Zhuo Zhang, Xianglin Shi

Faculty Publications

Carcinogenesis induced by environmental metal exposure is a major public health concern. The exact mechanisms underlying metal carcinogenesis remain elusive. In the past few decades, the relationship between metal-induced generation of reactive oxygen species (ROS) and the mechanism of metal carcinogenesis has been established. The carcinogenic process is a very complex one. In the early stage of metal carcinogenesis or cell transformation, high levels of ROS are oncogenic by causing DNA damage, genetic instability, epigenetic alteration, and metabolic reprogramming, leading to malignant transformation. In the second stage of metal carcinogenesis or the cancer development of metal-transformed cells, low levels of …

Go to article

The Social Structure Of Golfo Dulce Bottlenose Dolphins (Tursiops Truncatus) And The Influence Of Behavioural State, Kelsey Moreno, Alejandro Acevedo-Gutierrez Aug 2016

The Social Structure Of Golfo Dulce Bottlenose Dolphins (Tursiops Truncatus) And The Influence Of Behavioural State, Kelsey Moreno, Alejandro Acevedo-Gutierrez

Faculty Publications

Ecological factors such as habitat and food availability affect the social structure of bottlenose dolphins (Tursiops spp.). Here, we describe the social structure of bottlenose dolphins (T. truncatus) in Golfo Dulce, Costa Rica, a semi-enclosed, fjord-like tropical embayment resembling a pelagic system. We also examine behaviour-linked social strategies by comparing social structure relative to behavioural state: feeding versus non-feeding. We analysed 333 sightings over 210 days from boat-based surveys. Despite the uniqueness of the area, the 47 analysed adults had a social structure similar to other populations: a well-differentiated fission-fusion society with sex-specific patterns of associations and aggression. These results …

Go to article

Ecosystem Structure And Function In Two Branches Of An Eastern Minnesota, Usa, Trout Stream, Daniel J. Hornbach, Mark Hove, Maya Agata, Ellen Albright, Emily Cavazos, Clara Friedman, Katja Jay, Emily Johnson, Kari Johnson, Anna Staudenmaier Jul 2016

Ecosystem Structure And Function In Two Branches Of An Eastern Minnesota, Usa, Trout Stream, Daniel J. Hornbach, Mark Hove, Maya Agata, Ellen Albright, Emily Cavazos, Clara Friedman, Katja Jay, Emily Johnson, Kari Johnson, Anna Staudenmaier

Faculty Publications

No abstract provided.

Go to article

Invited Review: Mesenchymal Progenitor Cells In Intramuscular Connective Tissue Development, Z. G. Miao, L. P. Zhang, X. Fu, Q. Y. Yang, M. J. Zhu, M. V. Dodson, M. Du Jul 2016

Invited Review: Mesenchymal Progenitor Cells In Intramuscular Connective Tissue Development, Z. G. Miao, L. P. Zhang, X. Fu, Q. Y. Yang, M. J. Zhu, M. V. Dodson, M. Du

Faculty Publications

© The Animal Consortium 2015. The abundance and cross-linking of intramuscular connective tissue contributes to the background toughness of meat, and is thus undesirable. Connective tissue is mainly synthesized by intramuscular fibroblasts. Myocytes, adipocytes and fibroblasts are derived from a common pool of progenitor cells during the early embryonic development. It appears that multipotent mesenchymal stem cells first diverge into either myogenic or non-myogenic lineages; non-myogenic mesenchymal progenitors then develop into the stromal-vascular fraction of skeletal muscle wherein adipocytes, fibroblasts and derived mesenchymal progenitors reside. Because non-myogenic mesenchymal progenitors mainly undergo adipogenic or fibrogenic differentiation during muscle development, strengthening progenitor …

Go to article

Stabilization In A Chemostat With Sampled And Delayed Measurements, Frédéric Mazenc, Jérome Harmand, Michael Malisoff Jul 2016

Stabilization In A Chemostat With Sampled And Delayed Measurements, Frédéric Mazenc, Jérome Harmand, Michael Malisoff

Faculty Publications

We study chemostat models with constant substrate input concentrations. We allow growth functions that are not necessarily monotone. The measurement is the substrate concentration, which is piecewise constant with a nonconstant delay, so only sampled observations are available. Under new conditions on the size of the delay and on the largest sampling interval, we solve the problem of asymptotically stabilizing a componentwise positive equilibrium point with the dilution rate as the control. We use a new Lyapunov approach.

Go to article

Three Distinct Glutamate Decarboxylase Genes In Vertebrates, Brian P. Grone, Karen P. Maruska Jul 2016

Three Distinct Glutamate Decarboxylase Genes In Vertebrates, Brian P. Grone, Karen P. Maruska

Faculty Publications

Gamma-aminobutyric acid (GABA) is a widely conserved signaling molecule that in animals has been adapted as a neurotransmitter. GABA is synthesized from the amino acid glutamate by the action of glutamate decarboxylases (GADs). Two vertebrate genes, GAD1 and GAD2, encode distinct GAD proteins: GAD67 and GAD65, respectively. We have identified a third vertebrate GAD gene, GAD3. This gene is conserved in fishes as well as tetrapods. We analyzed protein sequence, gene structure, synteny, and phylogenetics to identify GAD3 as a homolog of GAD1 and GAD2. Interestingly, we found that GAD3 was lost in the hominid lineage. Because of the importance …

Go to article

Fulleretic Well-Defined Scaffolds: Donor–Fullerene Alignment Through Metal Coordination And Its Effect On Photophysics, Derek E. Williams, Ekaterina A. Dolgopolova, Danielle C. Godfrey, Evgeniya D. Ermolaeva, Perry J. Pellechia Dr., Andrew B. Greytak Prof. Dr., Mark Smith Dr., Stanislav M. Avdoshenko, Dr., Alexey A. Popov Dr., Natalia B. Shustova Prof. Dr. Jul 2016

Fulleretic Well-Defined Scaffolds: Donor–Fullerene Alignment Through Metal Coordination And Its Effect On Photophysics, Derek E. Williams, Ekaterina A. Dolgopolova, Danielle C. Godfrey, Evgeniya D. Ermolaeva, Perry J. Pellechia Dr., Andrew B. Greytak Prof. Dr., Mark Smith Dr., Stanislav M. Avdoshenko, Dr., Alexey A. Popov Dr., Natalia B. Shustova Prof. Dr.

Faculty Publications

Herein, we report the first example of a crystalline metal–donor–fullerene framework, in which control of the donor–fullerene mutual orientation was achieved through chemical bond formation, in particular, by metal coordination. The 13C cross-polarization magic-angle spinning NMR spectroscopy, X-ray diffraction, and time-resolved fluorescence spectroscopy were performed for comprehensive structural analysis and energy-transfer (ET) studies of the fulleretic donor–acceptor scaffold. Furthermore, in combination with photoluminescence measurements, the theoretical calculations of the spectral overlap function, Förster radius, excitation energies, and band structure were employed to elucidate the photophysical and ET processes in the prepared fulleretic material. We envision that the well-defined fulleretic donor–acceptor …

Go to article

A Comparative Study Of K-Spectrum-Based Error Correction Methods For Next-Generation Sequencing Data Analysis, Isaac Akogwu, Nan Wang, Chaoyang Zhang, Ping Gong Jul 2016

A Comparative Study Of K-Spectrum-Based Error Correction Methods For Next-Generation Sequencing Data Analysis, Isaac Akogwu, Nan Wang, Chaoyang Zhang, Ping Gong

Faculty Publications

Background: Innumerable opportunities for new genomic research have been stimulated by advancement in high-throughput next-generation sequencing (NGS). However, the pitfall of NGS data abundance is the complication of distinction between true biological variants and sequence error alterations during downstream analysis. Many error correction methods have been developed to correct erroneous NGS reads before further analysis, but independent evaluation of the impact of such dataset features as read length, genome size, and coverage depth on their performance is lacking. This comparative study aims to investigate the strength and weakness as well as limitations of some newest k-spectrum-based methods and …

Go to article

C60 And Sc3N@C80(Tmb-Ppo) Derivatives As Constituents Of Singlet Oxygen Generating, Thiol-Ene Polymer Nanocomposites, Emily M. Barker, Ashli R. Toles, Kyle A. Guess, J. Paige Buchanan Jul 2016

C60 And Sc3N@C80(Tmb-Ppo) Derivatives As Constituents Of Singlet Oxygen Generating, Thiol-Ene Polymer Nanocomposites, Emily M. Barker, Ashli R. Toles, Kyle A. Guess, J. Paige Buchanan

Faculty Publications

Numerous functionalization methods have been employed to increase the solubility, and therefore, the processability of fullerenes in composite structures, and of these radical addition reactions continue to be an important methodology. C60 and Sc3N@C80 derivatives were prepared via radical addition of the photodecomposition products from the commercial photoinitiator TMB-PPO, yielding C60(TMB-PPO)5 and Sc3N@C80(TMB-PPO)3 as preferred soluble derivatives obtained in high yields. Characterization of the mixture of isomers using standard techniques suggests an overall 1PPO:6TMB ratio of addends, reflecting the increased reactivity of the carbon radical. Although, a higher …

Go to article

The Use Of Aerial Rgb Imagery And Lidar In Comparing Ecological Habitats And Geomorphic Features On A Natural Versus Man-Made Barrier Island, Carlton P. Anderson, Gregory A. Carter, William R. Funderburk Jul 2016

The Use Of Aerial Rgb Imagery And Lidar In Comparing Ecological Habitats And Geomorphic Features On A Natural Versus Man-Made Barrier Island, Carlton P. Anderson, Gregory A. Carter, William R. Funderburk

Faculty Publications

The Mississippi (MS) barrier island chain along the northern Gulf of Mexico coastline is subject to rapid changes in habitat, geomorphology and elevation by natural and anthropogenic disturbances. The purpose of this study was to compare habitat type coverage with respective elevation, geomorphic features and short-term change between the naturally-formed East Ship Island and the man-made Sand Island. Ground surveys, multi-year remotely-sensed data, habitat classifications and digital elevation models were used to quantify short-term habitat and geomorphic change, as well as to examine the relationships between habitat types and micro-elevation. Habitat types and species composition were the same on both …

Go to article

High Resolution Laser Mass Spectrometry Bioimaging, Kermit K. Murray, Chinthaka A. Seneviratne, Suman Ghorai Jul 2016

High Resolution Laser Mass Spectrometry Bioimaging, Kermit K. Murray, Chinthaka A. Seneviratne, Suman Ghorai

Faculty Publications

© 2016 Elsevier Inc. Mass spectrometry imaging (MSI) was introduced more than five decades ago with secondary ion mass spectrometry (SIMS) and a decade later with laser desorption/ionization (LDI) mass spectrometry (MS). Large biomolecule imaging by matrix-assisted laser desorption/ionization (MALDI) was developed in the 1990s and ambient laser MS a decade ago. Although SIMS has been capable of imaging with a moderate mass range at sub-micrometer lateral resolution from its inception, laser MS requires additional effort to achieve a lateral resolution of 10 μm or below which is required to image at the size scale of single mammalian cells. This …

Go to article

First Prev Next Last