Digital Commons Network^™

The Impact Of Aquaculture On The Genetics And Distribution Of The Onuphid Annelid Diopatra Biscayensis, Matthew P. Galaska, David S. Wethey, Andrés Arias, Stanislas F. Dubios, Kenneth M. Halanych, Sarah A. Woodin

Faculty Publications

Aim

Evolutionary history of natural populations can be confounded by human intervention such as the case of decorator worm species Diopatra (Onuphidae), which have a history of being transported through anthropogenic activities. Because they build tubes and act as ecosystem engineers, they can have a large impact on the overall ecosystem in which they occur. One conspicuous member, Diopatra biscayensis, which was only described in 2012, has a fragmented distribution that includes the Bay of Biscay and the Normanno-Breton Gulf in the English Channel. This study explores the origin of these worms in the Normanno-Breton region, which has been …

Ramipril Blunts Glycerol-Induced Acute Renal Failure In Rats Through Its Antiapoptosis, Anti-Inflammatory, Antioxidant, And Renin-Inhibiting Properties, Adeolu Alex Adedapo, Ehizogie Ruth Osaretin, Olufunke Olubunmi Falayi, Ademola Adetokunbo Oyagbemi, Blessing Seun Ogunpolu, Temidayo Olutayo Omobowale, Oluwafemi Omoniyi Oguntibeju, Momoh Audu Yakubu

Faculty Publications

Acute kidney injury (AKI) is a malady with a sudden onset resulting in buildup of waste matters in the body, but a specific cure hasn't been found as a lasting solution to AKI. In this study, ramipril was evaluated for its potential therapy in glycerol-induced AKI in rats. Twenty animals were divided into four groups of five animals each. Group I was the control while group II was given glycerol on day 8 only, groups III and IV were administered with pioglitazone (reference drug) and ramipril for seven days respectively and on day 8 received glycerol. On the ninth day, …

Emerging Wetlands From River Diversions Can Sustain High Denitrification Rates In A Coastal Delta, Kiran Upreti, Victor H. Rivera-Monroy, Kanchan Maiti, Anne Giblin, James P. Geaghan

Faculty Publications

It is assumed that to treat excess NO3⁻ high soil organic matter content (%OM) is required to maintain high denitrification rates in natural or restored wetlands. However, this excess also represents a risk by increasing soil decomposition rates triggering peat collapse and wetland fragmentation. Here, we evaluated the role of %OM and temperature interactions controlling denitrification rates in eroding (Barataria Bay-BLC) and emerging (Wax Lake Delta-WLD) deltaic regions in coastal Louisiana using the isotope pairing (IPT) and N2:Ar techniques. We also assessed differences between total (direct denitrification + coupled nitrification-denitrification) and net (total denitrification minus nitrogen fixation) denitrification rates …

Time Lags: Insights From The U.S. Long Term Ecological Research Network, Edward B. Rastetter, Mark D. Ohman, Katherine J. Elliott, J. S. Rehage, Victor H. Rivera-Monroy, R. E. Boucek, Edward Castañeda-Moya, Tess M. Danielson, Laura Gough, Peter M. Groffman, C. Rhett Jackson, Chelcy Ford Miniat, Gaius R. Shaver

Faculty Publications

Ecosystems across the United States are changing in complex ways that are difficult to predict. Coordinated long-term research and analysis are required to assess how these changes will affect a diverse array of ecosystem services. This paper is part of a series that is a product of a synthesis effort of the U.S. National Science Foundation’s Long Term Ecological Research (LTER) network. This effort revealed that each LTER site had at least one compelling scientific case study about “what their site would look like” in 50 or 100 yr. As the site results were prepared, themes emerged, and the case …

An Efficient Alternative To The Cdc Gravid Trap For Southern House Mosquito (Diptera: Culicidae) Surveillance, Timothy D. Mcnamara, Thomas A. O'Shea-Wheller, Nicholas Delisi, Emily Dugas, Kevin A. Caillouet, Randy Vaeth, Dennis Wallette, Kristen Healy

Faculty Publications

West Nile virus (WNV) is the most prevalent arbovirus found throughout the United States. Surveillance of surface breeding Culex vectors involved in WNV transmission is primarily conducted using CDC Gravid traps. However, anecdotal claims from mosquito abatement districts in Louisiana assert that other trap types may be more suited to WNV surveillance. To test the validity of these assertions, we conducted a series of trapping trials and WNV surveillance over 3 yr to compare the efficacy of multiple trap types. First, we compared the CDC Gravid trap, CO2-baited New Standard Miniature Blacklight traps, and CO2-baited CDC light traps with either …

Citations Versus Expert Opinions: Citation Analysis Of Featured Reviews Of The American Mathematical Society, Lawrence Smolinsky, Daniel S. Sage, Aaron J. Lercher, Aaron Cao

Faculty Publications

Peer review and citation metrics are two means of gauging the value of scientific research, but the lack of publicly available peer review data makes the comparison of these methods difficult. Mathematics can serve as a useful laboratory for considering these questions because as an exact science, there is a narrow range of reasons for citations. In mathematics, virtually all published articles are post-publication reviewed by mathematicians in Mathematical Reviews (MathSciNet) and so the data set was essentially the Web of Science mathematics publications from 1993 to 2004. For a decade, especially important articles were singled out in Mathematical Reviews …

Elevated Incidences Of Antimicrobial Resistance And Multidrug Resistance In The Maumee River (Ohio, Usa), A Major Tributary Of Lake Erie, Maitreyee Mukherjee, Leah Marie, Cheyenne Liles, Nadia Mustafa, George Bullerjahn, Terry J. Gentry, John P. Brooks

Faculty Publications

Maumee River, the major tributary in the western basin of Lake Erie, serves as one of major sources of freshwater in the area, supplying potable, recreational, and industrial water. In this study we collected water samples from four sites in the Maumee River Bay between 2016–2017 and E. coli was isolated, enumerated, and analyzed for antimicrobial resistance (AMR) and multidrug resistance (MDR). Strikingly, 95% of the total isolates were found to be resistant to at least one antibiotic. A very high resistance to the drugs cephalothin (95.3%), ampicillin (38.3%), tetracycline (8.8%), gentamicin (8.2%), ciprofloxacin (4.2%), cefoperazone (4%), and sulfamethoxazole (1.5%) …

Heavy Metal-Resistant Filamentous Fungi As Potential Mercury Bioremediators, Cristina L. Văcar, Eniko Covaci, Somsubhra Chakraborty, Bin Li, David Weindorf, Tiberiu Frentiu, Marcel Pârvu, Dorina Podar

Faculty Publications

No abstract provided.

Conceptus Metabolomic Profiling Reveals Stage-Specific Phenotypes Leading Up To Pregnancy Recognition In Cattle†, Constantine A. Simintiras, José M. Sánchez, Michael Mcdonald, Elena O'Callaghan, Ahmed A. Aburima, Patrick Lonergan

Faculty Publications

Reproductive efficiency in livestock is a major driver of sustainable food production. The poorly understood process of ruminant conceptus elongation (a) prerequisites maternal pregnancy recognition, (b) is essential to successful pregnancy establishment, and (c) coincides with a period of significant conceptus mortality. Conceptuses at five key developmental stages between Days 8-16 were recovered and cultured in vitro for 6 h prior to conditioned media analysis by untargeted ultrahigh-performance liquid chromatography tandem mass spectroscopy. This global temporal biochemical interrogation of the ex situ bovine conceptus unearths two antithetical stage-specific metabolic phenotypes during tubular (metabolically retentive) vs. filamentous (secretory) development. Moreover, the …

Polycyclic Aromatic Hydrocarbon-Dna Adducts In Gulf Of Mexico Sperm Whale Skin Biopsies Collected In 2012, Miriam C. Poirier, Letizia Marsili, Maria Cristina Fossi, Céline A.J. Godard-Codding, Elena E. Hernandez-Ramon, Nancy Si, Kathyayini V. Divi, Rao L. Divi, Iain Kerr, John Pierce Wise, John Pierce Wise, Catherine F. Wise, Sandra S. Wise, Abou El Makarim Aboueissa, James T.F. Wise

Faculty Publications

The northern Gulf of Mexico has a long history of polycyclic aromatic hydrocarbon (PAH) contamination from anthropogenic activities, natural oil seepages, and the 2010 Deepwater Horizon explosion and oil spill. The continental shelf of the same area is a known breeding ground for sperm whales (Physeter macrocephalus). To evaluate PAH-DNA damage, a biomarker for potential cancer risk, we compared skin biopsies collected from Gulf of Mexico sperm whales in 2012 with skin biopsies collected from sperm whales in areas of the Pacific Ocean in 1999-2001. All samples were obtained by crossbow and comprised both epidermis and subcutaneous blubber. To evaluate …

Circadian Rhythms In Legumes: What Do We Know And What Else Should We Explore?, Hazel Marie Kugan, Nur Ardiyana Rejab, Nurul Amylia Sahruzaini, Jennifer Ann Harikrishna, Niranjan Baisakh, Acga Cheng

Faculty Publications

The natural timing devices of organisms, commonly known as biological clocks, are composed of specific complex folding molecules that interact to regulate the circadian rhythms. Circadian rhythms, the changes or processes that follow a 24‐h light–dark cycle, while endogenously programmed, are also influenced by environmental factors, especially in sessile organisms such as plants, which can impact ecosystems and crop productivity. Current knowledge of plant clocks emanates primarily from research on Arabidopsis, which identified the main components of the circadian gene regulation network. Nonetheless, there remain critical knowledge gaps related to the molecular components of circadian rhythms in important crop groups, …

Heterotrophic Nitrogen Fixation In Response To Nitrate Loading And Sediment Organic Matter In An Emerging Coastal Deltaic Floodplain Within The Mississippi River Delta Plain, Song Li, Robert R. Twilley, Aixin Hou

Faculty Publications

Increasing nitrate (NO3⁻) loading in rivers due to agricultural fertilization alters benthic nitrogen (N) cycling and shifts coastal wetlands from being a net source to net sink of reactive N. Heterotrophic N2 fixation that converts N2 to reactive N is often assumed negligible in eutrophic ecosystems and excluded in coastal N budget evaluations. We investigated N2 fixation and denitrification in response to increasing NO3⁻ loading (0, 10, and 100 μM) and sediment organic matter (OMsediment) concentrations in the emerging Wax Lake Delta. Continuous flow-through incubations with ³⁰N2 addition was applied to measure N2 fixation. The variation …

Genome-Wide Association Study Reveals Genomic Regions Associated With Fusarium Wilt Resistance In Common Bean, Jean Fausto De Carvalho Paulino, Caléo Panhoca De Almeida, César Júnior Bueno, Qijian Song, Roberto Fritsche-Neto, Sérgio Augusto Morais Carbonell, Alisson Fernando Chiorato, Luciana Lasry Benchimol-Reis

Faculty Publications

Fusarium wilt (Fusarium oxysporum f. sp. phaseoli, Fop) is one of the main fungal soil diseases in common bean. The aim of the present study was to identify genomic regions associated with Fop resistance through genome-wide association studies (GWAS) in a Mesoamerican Diversity Panel (MDP) and to identify potential common bean sources of Fop’s resistance. The MDP was genotyped with BARCBean6K_3BeadChip and evaluated for Fop resistance with two different monosporic strains using the root-dip method. Disease severity rating (DSR) and the area under the disease progress curve (AUDPC), at 21 days after inoculation (DAI), were used for GWAS performed with …

Insecticidal Rna Interference, Thinking Beyond Long Dsrna, Alex S. Flynt

Faculty Publications

Over 20 years ago double-stranded RNA (dsRNA) was described as the trigger of RNAi interference (RNAi)-based gene silencing. This paradigm has held since, especially for insect biopesticide technologies where dsRNAs, similar to those described in 1998, are used to inhibit gene expression. In the intervening years, investigation of RNAi pathways has revealed the small RNA effectors of RNAi are diverse and rapidly evolving. The rich biology of insect small RNAs suggests potential to use multiple RNAi modes for manipulating gene expression. By exploiting different RNAi pathways, the menu of options for pest control can be expanded and could lead to …

Mild Upgrading Of Biomass Pyrolysis Vapors Via Ex-Situ Catalytic Pyrolysis Over An Iron-Montmorillonite Catalyst, Candice R. Ellison, Dorin Boldor

Faculty Publications

Pyrolysis vapor upgrading can improve the stability of pyrolysis liquids to facilitate storage, transport, and drop in use as fuels and chemical feedstocks in existing refining infrastructure. This study investigates a low cost iron based catalyst for mild in-situ upgrading of fast pyrolysis vapors to increase the stability of pyrolysis liquid. Iron-doped montmorillonite K10 catalysts were characterized by ICP-OES, BET porosimetry, XRD, XPS, and NH3-TPD. The effect of three upgrading process parameters are evaluated by Box-Behnken experimental design using a fixed catalyst bed. Predictive model equations are developed based on response surface methodology to describe the effect of iron loading, …

Association Between Appendicular Skeletal Muscle Index And Leukocyte Telomere Length In Adults: A Study From National Health And Nutrition Examination Survey (Nhanes) 1999-2002, Lingzhi Chen, Nitin Shivappa Mbbs, Mph, Ph.D., Xiuxun Dong, Jinjing Ming

Faculty Publications

Background

A higher body mass index (BMI) is associated with shorter telomeres. The loss of muscle mass with aging is associated with adverse outcomes. The appendicular skeletal muscle index (ASMI) is currently used to quantify muscle mass.

Objective

We investigated the association of the ASMI with leukocyte telomere length in adult Americans.

Methods

This cross-sectional study used the National Health and Nutrition Examination Survey (NHANES) 1999–2002 dataset. Body composition was measured by dual-energy X-ray absorptiometry. Low muscle mass was defined using sex-specific thresholds of the appendicular skeletal muscle mass index (ASMI). The telomere-to-single-copy gene ratio (T/S ratio) was converted to …

Roboethics In Covid-19: A Case Study In Dentistry, Wendy C. Birmingham, Yaser Maddahi, Maryam Kalvandi, Sofya Langman, Nicole Capicotto, Kourosh Zareinia

Faculty Publications

The COVID-19 pandemic has caused dramatic effects on the healthcare system, businesses, and education. In many countries, businesses were shut down, universities and schools had to cancel in-person classes, and many workers had to work remotely and socially distance in order to prevent the spread of the virus. These measures opened the door for technologies such as robotics and artificial intelligence to play an important role in minimizing the negative effects of such closures. There have been many efforts in the design and development of robotic systems for applications such as disinfection and eldercare. Healthcare education has seen a lot …

Recent Advances In Understanding Tick And Rickettsiae Interactions, Shahid Karim, Deepak Kumar, Khemraj Budachetri

Faculty Publications

Ticks are haematophagous arthropods with unique molecular mechanisms for digesting host blood meal while acting as vectors for various pathogens of public health significance. The tick's pharmacologically active saliva plays a fundamental role in modulating the host's immune system for several days to weeks, depending on the tick species. The vector tick has also developed sophisticated molecular mechanisms to serve as a competent vector for pathogens, including the spotted fever group (SFG) rickettsiae. Evidence is still inadequate concerning tick–rickettsiae–host interactions and saliva-assisted transmission of the pathogen to the mammalian host. Rickettsia parkeri, of the SFG rickettsia, can cause a …

Characterization Of The Differential Expressed Genes And Transcriptomic Pathway Analysis In The Liver Of Sub-Adult Red Drum (Sciaenops Ocellatus) Exposed To Deepwater Horizon Chemically Dispersed Oil, Tracy A. Sherwood, Maria L. Rodgers, Andrea M. Tarnecki, Dana L. Wetzel

Faculty Publications

The Deepwater Horizon blowout resulted in the second-largest quantity of chemical dispersants used as a countermeasure for an open water oil spill in the Gulf of Mexico. Of which, the efficacy of dispersant as a mitigation strategy and its toxic effects on aquatic fauna remains controversial. To enhance our understanding of potential sub-lethal effects of exposure to chemically dispersed-oil, sub-adult red drum (Sciaenops ocellatus) were continuously exposed to a Corexit 9500: DWH crude oil chemically enhanced water accommodated fraction (CEWAF) for 3-days and transcriptomic responses were assessed in the liver. Differential expressed gene (DEG) analysis demonstrated that 63 …

Where To Draw The Line: The Endless Search For A Legal Competitive Edge, Andrew Brandt

Faculty Publications

No abstract provided.

Managing Family Stress: Coping, Adapting And Becoming Resilient, Jasmine Fraser

Faculty Publications

No abstract provided.

Comparable Response Of Wild Rodent Gut Microbiome To Anthropogenic Habitat Contamination, Anton Lavrinienko, Ann Hämäläinen, Rasmus Hindstrom, Eugene Tukalenko, Zbyszek Boratynski, Kati Kivisaari, Timothy Mousseau, Phillip C. Watts, Tapio Mappes

Faculty Publications

Species identity is thought to dominate over environment in shaping wild rodent gut microbiota, but it remains unknown whether the responses of host gut microbiota to shared anthropogenic habitat impacts are species-specific or if the general gut microbiota response is similar across host species. Here, we compare the influence of exposure to radionuclide contamination on the gut microbiota of four wild mouse species: Apodemus flavicollis, A. sylvaticus, A. speciosus and A. argenteus. Building on the evidence that radiation impacts bank vole (Myodes glareolus) gut microbiota, we hypothesized that radiation exposure has a general impact on rodent gut microbiota. Because we …

Potential Roles Of Endoplasmic Reticulum Stress And Cellular Proteins Implicated In Diabesity, Sagir Mustapha, Mustapha Mohammed, Ahmad Khusairi Azemi, Ismaeel Yunusa, Aishatu Shehu, Lukman Mustapha, Yusuf Wada, Mubarak Hussaini Ahmad, Wan Amir Wan Ahmad, Aida Hanum Ghulam Rasool, Siti Safiah Mokhtar

Faculty Publications

The role of the endoplasmic reticulum (ER) has evolved from protein synthesis, processing, and other secretory pathways to forming a foundation for lipid biosynthesis and other metabolic functions. Maintaining ER homeostasis is essential for normal cellular function and survival. An imbalance in the ER implied stressful conditions such as metabolic distress, which activates a protective process called unfolded protein response (UPR). This response is activated through some canonical branches of ER stress, i.e., the protein kinase RNA-like endoplasmic reticulum kinase (PERK), inositol-requiring enzyme 1α (IRE1α), and activating transcription factor 6 (ATF6). Therefore, chronic hyperglycemia, hyperinsulinemia, increased proinflammatory …

The Endocannabinoid Anandamide Attenuates Acute Respiratory Distress Syndrome By Downregulating Mirna That Target Inflammatory Pathways, Muthanna Sultan, Hasan Alghetaa, Amirah Mohammed, Osama A. Abdulla, Paul J. Wisniewski, Narendra Singh, Prakash Nagarkatti, Mitzi Nagarkatti

Faculty Publications

Acute respiratory distress syndrome (ARDS) is defined as a type of respiratory failure that is caused by a variety of insults such as pneumonia, sepsis, trauma and certain viral infections. In this study, we investigated the effect of an endocannabinoid, anandamide (AEA), on ARDS induced in the mouse by Staphylococcus Enterotoxin B (SEB). Administration of a single intranasal dose of SEB in mice and treated with exogenous AEA at a dose of 40 mg/kg body weight led to the amelioration of ARDS in mice. Clinically, plethysmography results indicated that there was an improvement in lung function after AEA treatment accompanied …

Associations Between Family-Based Stress And Dietary Inflammatory Potential Among Families With Preschool-Aged Children, Valerie Hruska, Nitin Shivappa Mbbs, Mph, Ph.D., James R. Hébert Scd, Alison M. Duncan, Jess Hines, David W. L. Ma

Faculty Publications

Chronic stress is known to influence dietary choices, and stressed families often report poorer diet quality; however, little is known about how family-based stress is linked with dietary patterns that promote inflammation. This study investigated associations between family-based stress and the inflammatory potential of the diet among preschool-aged children and their parents. Parents (n = 212 mothers, n = 146 fathers) and children (n = 130 girls, n = 123 boys; aged 18 months to 5 years) from 241 families participating in the Guelph Family Health Study were included in the analyses. Parents reported levels of parenting distress, depressive symptoms, …

Measuring And Leveraging Motives And Values In Dietary Interventions, Sarah J. Eustis, Gabrielle Turner-Mcgrievy, Swann A. Adams, James R. Hébert Scd

Faculty Publications

Why measure and leverage food motives and values? Every failure and every success in dietary change can be connected to motivation. Therefore, this research question naturally arises: How can food motives and values be measured and leveraged to improve diet outcomes from the individual to populations? There are four ways that food motives and values (FMVs) can assist researchers and health professionals. First, FMVs can help to create a personalized approach to dietary change. Second, FMVs can inform content for dietary interventions. Third, these FMV measures can be used in data analysis to elucidate differences in adherence and outcomes among …

Association Of Hair Concentrations Of Antiretrovirals With Virologic Outcomes Among People Living With Hiv In Guangxi, China, Quan Zhang, Xiaoming Li Ph.D., Shan Qiao Ph.D., Shuaifeng Liu, Zhiyong Shen, Yuejiao Zhou

Faculty Publications

Background: Hair concentrations of antiretrovirals are an innovative and non-invasive method for measuring cumulative antiretroviral exposure and assessing long-term antiretroviral adherence. This study aimed to examine hair concentrations of antiretrovirals in relation to virologic outcomes among PLHIV in Guangxi, China.
Methods: Cross-sectional data of hair concentrations of antiretrovirals and HIV viral load were collected from 215 PLHIV in Guangxi, China. Multivariate logistic regression analyses were used to examine the association of hair concentrations of antiretrovirals with virologic outcomes.
Results: Of the 215 participants, 215, 67, and 163 PLHIV are receiving lamivudine, zidovudine, and efavirenz, respectively. Multivariate analysis revealed that hair …

The Modern Plant Breeding Triangle: Optimizing The Use Of Genomics, Phenomics, And Enviromics Data, Jose Crossa, Roberto Fritsche-Neto, Osval A. Montesinos-Lopez, Germano Costa-Neto, Susanne Dreisigacker, Abelardo Montesinos-Lopez, Alison R. Bentley

Faculty Publications

No abstract provided.

Trichoderma Asperellum Inoculation As A Tool For Attenuating Drought Stress In Sugarcane, Daniele Scudeletti, Carlos Alexandre Costa Crusciol, João William Bossolani, Luiz Gustavo Moretti, Letusa Momesso, Brenda Servaz Tubaña, Sérgio Gustavo Quassi De Castro, Elisa Fidêncio De Oliveira, Mariangela Hungria

Faculty Publications

Drought stress is an important concern worldwide which reduces crop yield and quality. To alleviate this problem, Trichoderma asperellum has been used as a plant growth-promoting fungus capable of inducing plant tolerance to biotic and abiotic stresses. Here, we examined the effect of T. asperellum inoculation on sugarcane plant above and belowground development under drought stress and investigated the role of this fungus on inducing tolerance to drought at physiological and biochemical levels. The experiment was performed in pots under greenhouse conditions, with four treatments and four replicates. The treatments consisted of sugarcane plants inoculated or not with T. asperellum …

The Malina Oceanographic Expedition: How Do Changes In Ice Cover, Permafrost And Uv Radiation Impact Biodiversity And Biogeochemical Fluxes In The Arctic Ocean?, Philippe Massicotte, Rainer M.W. Amon, Antoine David, Sergio Balzano, Simon Bélanger, Ronald Benner, Dominique Boeuf, Annick Bricaud, Flavienne Bruyant, Gwenaëlle Chaillou, Malik Chami, Bruno Charrière, Jing Chen, Hervé Claustre, Pierre Coupel, Nicole Delsaut, David Doxaran, Jens Ehn, Cédric Fichot, Marie-Hélène Forget, Et. Al.

Faculty Publications

The MALINA oceanographic campaign was conducted during summer 2009 to investigate the carbon stocks and the processes controlling the carbon fluxes in the Mackenzie River estuary and the Beaufort Sea. During the campaign, an extensive suite of physical, chemical and biological variables were measured across seven shelf-basin transects (south-north) to capture the meridional gradient between the estuary and the open ocean. Key variables such as temperature, absolute salinity, radiance, irradiance, nutrient concentrations, chlorophyll a concentration, bacteria, phytoplankton and zooplankton abundance and taxonomy, and carbon stocks and fluxes were routinely measured onboard the Canadian research icebreaker CCGS Amundsen and from a …