Digital Commons Network^™

Ecology Of Family Experiences: Contextualizing Family Leisure For Human Development & Family Relations, Karen K. Melton, Camilla Hodge, Mat D. Duerden

Faculty Publications

All family leisure is not equal. Yet, little is known about the mechanisms linking different types of family leisure to different human development and family relations outcomes. The Ecology of Family Experiences (EFE) framework provides a sensitizing lens for the study of the conditions under which family leisure is beneficial to individuals and families. Specifically, the framework suggests three domains—Family, Activity, and Time—iteratively interact to generate different levels of individual and family outcomes (i.e., responses, meaning, and development). The EFE necessitates research built on ecologically valid study designs that incorporate innovative measurement approaches. Scholars using such approaches can increase the …

Effects Of Co-Incubation Of Lps-Stimulated Raw 264.7 Macrophages On Leptin Production By 3t3-L1 Adipocytes: A Method For Co-Incubating Distinct Adipose Tissue Cell Lines, Cristina Caldari, Jordan Beck

Faculty Publications

No abstract provided.

Both Consumptive And Non-Consumptive Effects Of Predators Impact Mosquito Populations And Have Implications For Disease Transmission, Marie C. Russell, Catherine M. Herzog, Zachary Gajewski, Chloe Ramsay, Andy Mccall

Faculty Publications

No abstract provided.

Local Biodiversity Change Reflects Interactions Among Changing Abundance, Evenness, And Richness, Shane A. Blowes, Gergana N. Daskalova, Maria Dornelas, Thore Engel, Nicholas J. Gotelli, Anne E. Magurran, Ines S. Martins, Brian Mcgill, Daniel J. Mcglinn, Alban Sagouis, Hideyasu Shimadzu, Sarah R. Supp, Jonathan M. Chase

Faculty Publications

No abstract provided.

Growth In Snapping Turtle, Chelydra Serpentina (Testudines: Chelydridae) In Northern Indiana, John B. Iverson, Geoffrey R. Smith, Jessica E. Rettig

Faculty Publications

No abstract provided.

Wetland Construction, Restoration, And Integration: A Comparative Review, Douglas J. Spieles

Faculty Publications

No abstract provided.

"Trading Western Suits For Monastic Robes" : Remaking Tibetan Buddhism In The Chinese Religious Revival, Jue Liang

Faculty Publications

No abstract provided.

Libraries In The Doughnut Economy, Monika Antonelli, Rene Tanner, Rebekkah Smith Aldrich, Adrian K. Ho

Faculty Publications

This chapter unpacks the principles behind Doughnut Economics and explains how libraries can lead a long overdue social transition by incorporating the principles into their policies and operations. The actualization of Doughnut Economics will bring about a positive transformation of people’s behavior, which in turn will shift the focus of the economy from unfettered growth and opportunistic monetization to the well-being of people and biodiversity on the planet. In addition, libraries can help facilitate a redistribution of wealth in its various forms by supporting and promoting knowledge sharing. The chapter concludes with a discussion of five simple acts that drive …

The Impact Of Sexual Abuse On Children, Alina M. Baltazar

Faculty Publications

No abstract provided.

Waldenström Macroglobulinemia: Mechanisms Of Disease Progression And Current Therapies, Ava J. Boutilier, Lina Huang, Sherine F. Elsawa

Faculty Publications

Waldenström macroglobulinemia is an indolent, B-cell lymphoma without a known cure. The bone marrow microenvironment and cytokines both play key roles in Waldenström macroglobulinemia (WM) tumor progression. Only one FDA-approved drug exists for the treatment of WM, Ibrutinib, but treatment plans involve a variety of drugs and inhibitors. This review explores avenues of tumor progression and targeted drug therapy that have been investigated in WM and related B-cell lymphomas.

Pieces Of The Whole: Using The Research Process To Integrate Data Management And Information Literacy Skills, Patricia Condon, Megan Bresnahan, Eugenia Opuda

Faculty Publications

The research process is naturally embraced as part of the academic curriculum in higher education. Graduate students write theses and dissertations based on their original scholarships, undergraduate stu­dents produce papers for courses and work in labs or in the field, and both participate in faculty-led research projects. The research process is tack­led holistically through coursework, yet when library instructors are invited to teach students about information literacy and research data management topics, these may be presented as tangential to or mistimed with other course content and learning activities. In this chapter, the authors present a com­prehensive, student-centered model for teaching …

Bottom‐Up Versus Top‐Down Strategies For Morphology Control In Polymer‐Based Biomedical Materials, Alexander B. Cook, Tristan D. Clemons

Faculty Publications

The size and shape of polymer materials is becoming an increasingly important property in accessing new functions and applications of nano-/microparticles in many scientific fields. New synthetic methods have allowed unprecedented capability for the facile fabrication of anisotropic and shape-defined nanomaterials. Bottom-up approaches including: emulsion polymerization techniques, amphiphile self-assembly, and polymerization-induced self-assembly, can lead to polymer particles with precise dimensions in the nanoscale. Top-down methods such as lithographic templating, and 3D printing, have increased the access to unique particle shapes. In this review, these recent developments are appraised and contrasted, with future research directions providing that focus on biomedical applications. …

Viral Sovereignty,Vaccine Diplomacy,And Vaccine Nationalism: The Institutions Of Global Vaccine Access, Sam F. Halabi, Ana Santos Rutschman

Faculty Publications

The COVID-19 pandemic has triggered a global vaccine race. Distributive questions about which countries will receive scarce doses and under which conditions pervade international law and diplomacy. This Article is the first to describe the phenomena that have driven the development of international vaccine-sharing mechanisms, identify the international organizational forces that explain the phenomena, and explain how international organizations may facilitate international cooperation before, during, and after global crises.

This Article explores the longstanding dissociation between global public health imperatives and nationalist responses to pandemics within the frameworks of “vaccine nationalism,” “viral sovereignty,” and “vaccine diplomacy.” The Article then considers …

When Cpr Is Needed, Robert E. Zdor

Faculty Publications

Column: Practical Pointers

Promoting Vaccine Innovation, Mirit Eyal-Cohen, Ana Santos Rutschman

Faculty Publications

As society grows to understand the need to promote innovation, policymakers try to employ an arsenal of policy tools, from traditional intellectual property (“IP”) to newer tools such as grants, regulatory vouchers, and prizes. This Article argues that these frameworks crowd out certain types of investments in innovation projects that have a high social value. Vaccine innovation is a case in point. Despite the immense socioeconomic benefit of vaccines, existing policies have been limited in fostering investments in this space. This is because they fail to directly address the relevant bottleneck issues distinct to vaccine development.

This Article offers a …

Exploring The Relationships Among Stoichiometric Coefficients, Number Of Transferred Electrons, Mean Oxidation Number Of Carbons, And Oxidative Ratio In Organic Combustion Reactions, Pong Kau Yuen, Cheng Man Diana Lau

Faculty Publications

Combustion reactions, stoichiometry, and redox reactions are some of the basic contents in chemistry curriculum. Although the counting of transferred electrons is critical in redox reactions, assigning mean oxidation number of organic carbons (ONc) is not always easy. Even though the relationship between the oxidative ratio (OR) and ONc is known, the relationship between the number of transferred electrons (Te−) and OR has not been thoroughly studied. The H-atom method has already been developed to balance and deduct organic combustion reactions. It can be used further to help establish the relationships among the stoichiometric coefficients (SC), the number of transferred …

Protocol For Escitalopram And Language Intervention For Subacute Aphasia (Elisa): A Randomized, Double Blind, Placebo-Controlled Trial, Melissa D. Stockbridge, Julius Fridriksson, Souvik Sen, Leonardo Bonilha

Faculty Publications

In this forthcoming multicenter, prospective, randomized, double-blind placebo-controlled trial, we will investigate the augmentative effects of a selective serotonin reuptake inhibitor, escitalopram, on language therapy in individuals with post-stroke aphasia. We hypothesize that, when combined with language therapy, daily escitalopram will result in greater improvement than placebo in an untrained picture naming task (Philadelphia Naming Test short form) administered one week after the end of language therapy. We also will examine whether escitalopram's effect on language is independent of its effect on depression, varies with lesion location, or is associated with increased functional connectivity within the left hemisphere. Finally, we …

A Semantically Enriched Taxonomic Revision Of Gryonoides Dodd, 1920 (Hymenoptera, Scelionidae), With A Review Of The Hosts Of Teleasinae, István Mikó, Lubomir Masner, Jonah M. Ulmer, Monique Raymond, Julia Hobbie, Sergei Tarasov, Cecilia Beatriz Margaría, Katja C. Seltmann, Elijah J. Talamas

Faculty Publications

Teleasinae are commonly collected scelionids that are the only known egg parasitoids of carabid beetles and therefore play a crucial role in shaping carabid populations in natural and agricultural ecosystems. We review the available host information of Teleasinae, report a new host record, and revise Gryonoides Dodd, 1920, a morphologically distinct teleasine genus. We review the generic concept of Gryonoides and provide diagnoses and descriptions of thirteen Gryonoides species and two varieties: G. glabriceps Dodd, 1920, G. pulchellus Dodd, 1920 (= G. doddi Ogloblin, 1967, syn. nov. and G. pulchricornis Ogloblin, 1967, syn. nov.), G. brasiliensis Masner & Mikó, sp. …

A Global Ocean Oxygen Database And Atlas For Assessing And Predicting Deoxygenation And Ocean Health In The Open And Coastal Ocean, Marilaure Grégoire, Véronique Garçon, Hernan Garcia, Denise Breitburg, Kirsten Isensee, Andreas Oschlies, Maciej Telszewski, Alexander Barth, Henry C. Bittig, Jacob Carstensen, Thierry Carval, Fei Chai, Francisco Chavez, Daniel Conley, Laurent Coppola, Sean Crowe, Kim Currie, Minhan Dai, Bruno Deflandre, Boris Dewitte, Robert Diaz, Emilio Garcia-Robledo, Denis Gilbert, Alessandra Giorgetti, Ronnie Glud, Dimitri Gutierrez, Shigeki Hosoda, Masao Ishii, Gil Jacinto, Chris Langdon, Siv K. Lauvset, Lisa A. Levin, Karin E. Limburg

Faculty Publications

In this paper, we outline the need for a coordinated international effort toward the building of an open-access Global Ocean Oxygen Database and ATlas (GO2DAT) complying with the FAIR principles (Findable, Accessible, Interoperable, and Reusable). GO2DAT will combine data from the coastal and open ocean, as measured by the chemical Winkler titration method or by sensors (e.g., optodes, electrodes) from Eulerian and Lagrangian platforms (e.g., ships, moorings, profiling floats, gliders, ships of opportunities, marine mammals, cabled observatories). GO2DAT will further adopt a community-agreed, fully documented metadata format and a consistent quality control (QC) procedure and quality flagging (QF) system. GO2DAT …

Unravelling Rubber Tree Growth By Integrating Gwas And Biological Network-Based Approaches, Felipe Roberto Francisco, Alexandre Hild Aono, Carla Cristina Da Silva, Paulo S. Gonçalves, Erivaldo J. Scaloppi Junior, Vincent Le Guen, Roberto Fritsche-Neto, Livia Moura Souza, Anete Pereira De Souza

Faculty Publications

Hevea brasiliensis (rubber tree) is a large tree species of the Euphorbiaceae family with inestimable economic importance. Rubber tree breeding programs currently aim to improve growth and production, and the use of early genotype selection technologies can accelerate such processes, mainly with the incorporation of genomic tools, such as marker-assisted selection (MAS). However, few quantitative trait loci (QTLs) have been used successfully in MAS for complex characteristics. Recent research shows the efficiency of genome-wide association studies (GWAS) for locating QTL regions in different populations. In this way, the integration of GWAS, RNA-sequencing (RNA-Seq) methodologies, coexpression networks and enzyme networks can …

A New Criterion For Fluoroquinolone-Associated Disability Diagnosis: Functional Gastrointestinal Disorders, Deanna N. Cannizzaro, Lydia F. Naughton, Maya Z. Freeman, Linda Martin, Charles L. Bennett M.D., Ph.D., Cecilia Bove

Faculty Publications

Background and Objectives: Fluoroquinolones (FQs) are a broad-spectrum class of antibiotics routinely prescribed for common bacterial infections despite recent recommendations to use them only for life-threatening cases. In addition to their antimicrobial properties, FQs act in the central nervous system as GABAA receptor inhibitors, which could potentially affect functionality of the vagus nerve at the forefront of gastrointestinal (GI) tract function. Alterations in neural control of digestion have been shown to be linked to Functional Gastrointestinal Disorders (FGIDs), which are usually diagnosed based on self-reported symptoms. The aim of this study was to assess the incidence of FGIDs following FQ …

Salt Marshes As Groundwater Buffers For Development: A Survey Of South Carolina Salt Marsh Basins, Alicia M. Wilson, Meghan Shanahan, Erik M. Smith

Faculty Publications

Salt marshes serve as zones of intense groundwater mixing and reaction between freshwater uplands and estuaries. This raises the question of whether the impacts of upland development on nutrient and carbon species can be transmitted through salt marshes via groundwater, or whether salt marshes can buffer estuarine waters from coastal development. We sampled groundwater from fifteen tidal creek basins in South Carolina to test for compositional differences associated with development and marsh width. Groundwater samples from near creekbanks and below freshwater uplands were analyzed for salinity, total dissolved nitrogen and phosphorus, and dissolved organic carbon. Analyses revealed significantly higher TDN …

First Record Of Fungal Diversity In The Tropical And Warm-Temperate Middle Miocene Climate Optimum Forests Of Eurasia, Ingrid C. Romero, Noelia B. Nuñez Otaño, Martha E. Gibson, Tyler M. Spears, C. Jolene Fairchild, Laikin Tarlton, Savannah Jones, Harvey E. Belkin, Sophie Warny, Matthew J. Pound, Jennifer M.K. O’Keefe

Faculty Publications

The middle Miocene Climate Optimum (MMCO) was the warmest interval of the last 23 million years and is one of the best analogs for proposed future climate change scenarios. Fungi play a key role in the terrestrial carbon cycle as dominant decomposers of plant debris, and through their interactions with plants and other organisms as symbionts, parasites, and endobionts. Thus, their study in the fossil record, especially during the MMCO, is essential to better understand biodiversity changes and terrestrial carbon cycle dynamics in past analogous environments, as well as to model future ecological and climatic scenarios. The fossil record also …

Hydrodynamic Assessment Of Natural And Nature-Based Features For Escatawpa River And Grand Bay In The Northern Gulf Of Mexico, Peter Bacopoulos, Karim Alizad, Davina Passeri, Matthew Bilskie, Stephen Medeiros, Scott Hagen

Faculty Publications

This presentation showcases a hydrodynamic assessment of natural and nature-based features (NNBFs) for the Pascagoula River, the Escatawpa River and Grand Bay, located along the Mississippi coast of the northern Gulf of Mexico. Two separate NNBF projects are being considered to: (1) restore the historical footprint (ca. 1848) of Grand Batture Island for coastal protection purposes; and (2) reconnect the hydraulics between the Escatawpa River and Grand Bay for ecosystem services purposes. The intended coastal protection benefits of the first project include buffering agency to wave attack and attenuation of storm surge with the restored island. The intended ecosystem services …

Nutrient Intake And Dietary Inflammatory Potential In Current And Recovered Anorexia Nervosa, Olivia Patsalos, Bethan Dalton, Christia Kyprianou, Joseph Firth, Nitin Shivappa Mbbs, Mph, Ph.D., James Hébert Scd, Ulrike Schmidt, Hubertus Himmerich

Faculty Publications

Anorexia nervosa (AN) is characterised by disrupted and restrictive eating patterns. Recent investigations and meta-analyses have found altered concentrations of inflammatory markers in people with current AN. We aimed to assess nutrient intake in participants with current or recovered AN, as compared to healthy individuals, and explore group differences in dietary inflammatory potential as a possible explanation for the observed alterations in inflammatory markers. We recruited participants with current AN (n = 51), those recovered from AN (n = 23), and healthy controls (n = 49). We used the Food Frequency Questionnaire (FFQ), to calculate a Dietary …

Fungal Community And Functional Responses To Soil Warming Are Greater Than For Soil Nitrogen Enrichment, Mark A. Anthony, Melissa A. Knorr, Jessica A. M. Moore, M. Simpson, Serita D. Frey

Faculty Publications

Soil fungi are key regulators of forest carbon cycling and their responses to global change have effects that ripple throughout ecosystems. Global changes are expected to push many fungi beyond their environmental niches, but there are relatively few studies involving multiple, simultaneous global change factors. Here, we studied soil fungal diversity, community composition, co-occurrence patterns, and decomposition gene responses to 10 years of soil warming and nitrogen addition, alone and in combination. We specifically examined whether there were fungal community characteristics that could explain changes in soil carbon storage and organic matter chemistry in chronically warmed and fertilized soil. We …

Preliminary Tests Of Dosimetric Quality And Projected Therapeutic Outcomes Of Multi-Phase 4d Radiotherapy With Proton And Carbon Ion Beams, Michelle Lis, Wayne Newhauser, Marco Donetti, Moritz Wolf, Timo Steinsberger, Athena Paz, Christian Graeff

Faculty Publications

Objective. The purpose of this study was to perform preliminary pre-clinical tests to compare the dosimetric quality of two approaches to treating moving tumors with ion beams: synchronously delivering the beam with the motion of a moving planning target volume (PTV) using the recently developed multi-phase 4D dose delivery (MP4D) approach, and asynchronously delivering the ion beam to a motion-encompassing internal tumor volume (ITV) combined with rescanning. Approach. We created 4D optimized treatment plans with proton and carbon ion beams for two patients who had previously received treatment for non-small cell lung cancer. For each patient, we created several treatment …

A Morphological And Histological Investigation Of Imperfect Lungfish Fin Regeneration, Vivien Bothe, Igor Schneider, Nadia B. Fröbisch

Faculty Publications

Regeneration, the replacement of body parts in a living animal, has excited scientists for centuries and our knowledge of vertebrate appendage regeneration has increased significantly over the past decades. While the ability of amniotes to regenerate body parts is very limited, members of other vertebrate clades have been shown to have rather high regenerative capacities. Among tetrapods (four-limbed vertebrates), only salamanders show unparalleled capacities of epimorphic tissue regeneration including replacement of organ and body parts in an apparently perfect fashion. The closest living relatives of Tetrapoda, the lungfish, show regenerative abilities that are comparable to those of salamanders and recent …

Single-Variable Porous Nanomaterial Series From Polymer Structure-Directing Agents, Morgan Stefik

Faculty Publications

Block polymer structure-directing agents (SDA) enable the production of porous nanoscale materials. Most strategies rely upon polymer equilibration where diverse morphologies are realized in porous functional materials. This review details how solvent selectivity determines the polymer SDA behaviors, spanning from bulk-type to solution-type. Equilibrating behavior of either type, however, obscures nanostructure cause-and-effect since the resulting sample series convolve multiple spatial variations. Solution-type SDA behaviors include both dynamic and persistent micelles. Persistent micelle templates (PMT) use high solvent selectivity for kinetic entrapment. PMTs enable independent wall thickness control with demonstrated 2 Å precision alterations. Unimodal PMT pore size distributions have spanned …

Oxidative Stress Indices In Asd Children In Sub-Sahara Africa, Ishiaq Olayinka Omotosho, Adekunbi Olufunke Akinade, Ikeoluwa Abiola Lagunju, Momoh A. Yakubu

Faculty Publications

Background: The pathogenesis of autism spectrum disorder (ASD) remains a medical challenge even in the developed world. Although genetics and epigenetic factors have been variously indicted as major causes of the disorder, development of oxidative stress especially in the formative years of children has equally gained prominence as an etiological basis of the disorder. Oxidative stress is characterized by the production of excessive amounts of free radicals, decreased levels of antioxidants with the attendant imbalance in oxidant/antioxidant ratio. This study was designed to determine the levels of essential metals [magnesium (Mg), zinc (Zn), and copper (Cu)] and toxic metal, lead …