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Articles 1771 - 1800 of 2819
Full-Text Articles in Entire DC Network
25-Hydroxyvitamin D Levels In African American And Nigerian Women, Ramon A. Durazo-Arvizu, John F. Aloia, Lara R. Dugas, Bamidele O. Tayo, David A. Shoham, Anne Marie Bertino, James K. Yeh, Richard S. Cooper, Amy Luke
25-Hydroxyvitamin D Levels In African American And Nigerian Women, Ramon A. Durazo-Arvizu, John F. Aloia, Lara R. Dugas, Bamidele O. Tayo, David A. Shoham, Anne Marie Bertino, James K. Yeh, Richard S. Cooper, Amy Luke
Faculty Publications
Objectives: African Americans (AA) have substantially lower levels of circulating 25-hydroxyvitamin D (25(OH)D) than whites. We compared population-based samples of 25(OH)D in women of African descent from Nigeria and metropolitan Chicago. Methods: One hundred women of Yoruba ethnicity from southwest Nigeria and 94 African American women from metropolitan Chicago were recruited and compared using a standardized survey protocol and the same laboratory assay for 25(OH)D. Results: Mean 25(OH)D levels were 64 nmol/l among the Nigerians and 29 nmol/l among the AA. Only 10% of the values were shared in common between the groups, and 76% of the Nigerians were above …
Adults With Greater Weight Satisfaction Report More Positive Health Behaviors And Have Better Health Status Regardless Of Bmi, Christine E. Blake Ph.D., Rd, James R. Hébert Scd, Duck Chul Lee, Swann A. Adams, Susan E. Steck Phd, Mph, Rd, Xuemei Sui M.D., M.P.H., Ph.D., Jennifer L. Kuk, Meghan Baruth, Steven N. Blair
Adults With Greater Weight Satisfaction Report More Positive Health Behaviors And Have Better Health Status Regardless Of Bmi, Christine E. Blake Ph.D., Rd, James R. Hébert Scd, Duck Chul Lee, Swann A. Adams, Susan E. Steck Phd, Mph, Rd, Xuemei Sui M.D., M.P.H., Ph.D., Jennifer L. Kuk, Meghan Baruth, Steven N. Blair
Faculty Publications
Background. Prior studies suggest that weight satisfaction may preclude changes in behavior that lead to healthier weight among individuals who are overweight or obese. Objective. To gain a better understanding of complex relationships between weight satisfaction, weight-related health behaviors, and health outcomes. Design. Cross-sectional analysis of data from the Aerobics Center Longitudinal Study (ACLS). Participants. Large mixed-gender cohort of primarily white, middle-to-upper socioeconomic status (SES) adults with baseline examination between 1987 and 2002 (n = 19,003). Main Outcome Variables. Weight satisfaction, weight-related health behaviors, chronic health conditions, and clinical health indicators. Statistical Analyses Performed. Chi-square test, t-tests, and linear and …
Lesions Of The Intergeniculate Leaflet Lead To A Reorganization In Circadian Regulation And A Reversal In Masking Responses To Photic Stimuli In The Nile Grass Rat, Andrew J. Gall, Laura Smale, Lily Yan, Antonio A. Nunez
Lesions Of The Intergeniculate Leaflet Lead To A Reorganization In Circadian Regulation And A Reversal In Masking Responses To Photic Stimuli In The Nile Grass Rat, Andrew J. Gall, Laura Smale, Lily Yan, Antonio A. Nunez
Faculty Publications
Light influences the daily patterning of behavior by entraining circadian rhythms and through its acute effects on activity levels (masking). Mechanisms of entrainment are quite similar across species, but masking can be very different. Specifically, in diurnal species, light generally increases locomotor activity (positive masking), and in nocturnal ones, it generally suppresses it (negative masking). The intergeniculate leaflet (IGL), a subdivision of the lateral geniculate complex, receives direct retinal input and is reciprocally connected with the primary circadian clock, the suprachiasmatic nucleus (SCN). Here, we evaluated the influence of the IGL on masking and the circadian system in a diurnal …
The Effect Of Prenatal And Postnatal Care On Childhood Obesity, Michael M. O. Seipel, Kevin Shafer
The Effect Of Prenatal And Postnatal Care On Childhood Obesity, Michael M. O. Seipel, Kevin Shafer
Faculty Publications
Childhood obesity continues to be a major public health problem in the United States. If this problem is unresolved, some children will be at risk for disorders such as type 2 diabetes, high blood pressure, and cancer and will become a high economic and social burden for society. Using the National Longitudinal Survey of Youth, Child and Young Adult sample (N = 6,643), this study examined the relationship between the effect of pre- and postnatal characteristics and obesity. The findings of this study show that the probability of childhood obesity can be lessened if pregnant women do not smoke and …
Association Between Adverse Childhood Experiences And Diagnosis Of Cancer, Monique J. Brown, Leroy R. Thacker, Steven A. Cohen
Association Between Adverse Childhood Experiences And Diagnosis Of Cancer, Monique J. Brown, Leroy R. Thacker, Steven A. Cohen
Faculty Publications
Objective: Adverse childhood experiences (ACEs) are linked to multiple adverse health outcomes. This study examined the association between ACEs and cancer diagnosis.
Methods: Data from the 2010 Behavioral Risk Factor Surveillance System (BRFSS) survey were used. The BRFSS is the largest ongoing telephone health survey, conducted in all US states, the District of Columbia, Puerto Rico, Guam and the U.S. Virgin Islands, and provides data on a variety of health issues among the non-institutionalized adult population. Principal component analysis (PCA) was used to derive components for ACEs. Multivariable logistic regression models were used to provide adjusted odds ratios (OR) and …
Reevaluating The Conceptual Framework For Applied Research On Host-Plant Resistance, Michael J. Stout
Reevaluating The Conceptual Framework For Applied Research On Host-Plant Resistance, Michael J. Stout
Faculty Publications
Applied research on host-plant resistance to arthropod pests has been guided over the past 60 years by a framework originally developed by Reginald Painter in his 1951 book, Insect Resistance in Crop Plants. Painter divided the "phenomena" of resistance into three "mechanisms," nonpreference (later renamed antixenosis), antibiosis, and tolerance. The weaknesses of this framework are discussed. In particular, this trichotomous framework does not encompass all known mechanisms of resistance, and the antixenosis and antibiosis categories are ambiguous and inseparable in practice. These features have perhaps led to a simplistic approach to understanding arthropod resistance in crop plants. A dichotomous scheme …
A Meta-Analysis Identifies New Loci Associated With Body Mass Index In Individuals Of African Ancestry, Keri L. Monda, Gary K. Chen, Kira C. Taylor, Cameron Palmer, Todd L. Edwards, Leslie A. Lange, Maggie C.Y. Ng, Adebowale A. Adeyemo, Matthew A. Allison, Lawrence F. Bielak, Guanjie Chen, Mariaelisa Graff, Marguerite R. Irvin, Suhn K. Rhie, Guo Li, Yongmei Liu, Youfang Liu, Yingchang Lu, Michael A. Nalls, Yan V. Sun, Mary K. Wojczynski, Lisa R. Yanek, Melinda C. Aldrich, Adeyinka Ademola, Christopher I. Amos, Elisa V. Bandera, Cathryn H. Bock, Angela Britton, Ulrich Broeckel, Quiyin Cai, Neil E. Caporaso, Chris S. Carlson, John Carpten
A Meta-Analysis Identifies New Loci Associated With Body Mass Index In Individuals Of African Ancestry, Keri L. Monda, Gary K. Chen, Kira C. Taylor, Cameron Palmer, Todd L. Edwards, Leslie A. Lange, Maggie C.Y. Ng, Adebowale A. Adeyemo, Matthew A. Allison, Lawrence F. Bielak, Guanjie Chen, Mariaelisa Graff, Marguerite R. Irvin, Suhn K. Rhie, Guo Li, Yongmei Liu, Youfang Liu, Yingchang Lu, Michael A. Nalls, Yan V. Sun, Mary K. Wojczynski, Lisa R. Yanek, Melinda C. Aldrich, Adeyinka Ademola, Christopher I. Amos, Elisa V. Bandera, Cathryn H. Bock, Angela Britton, Ulrich Broeckel, Quiyin Cai, Neil E. Caporaso, Chris S. Carlson, John Carpten
Faculty Publications
Genome-wide association studies (GWAS) have identified 36 loci associated with body mass index (BMI), predominantly in populations of European ancestry. We conducted a meta-analysis to examine the association of >3.2 million SNPs with BMI in 39,144 men and women of African ancestry and followed up the most significant associations in an additional 32,268 individuals of African ancestry. We identified one new locus at 5q33 (GALNT10, rs7708584, P = 3.4 × 10-11) and another at 7p15 when we included data from the GIANT consortium (MIR148A-NFE2L3, rs10261878, P = 1.2 × 10-10). We also found suggestive evidence of an association at a …
Prevalence And Predictors Of Smoking In A Mining Town In Kitwe, Zambia: A 2011 Population-Based Survey, Cosmas Zyaambo, Olesegun Babaniyi, Peter Songolo, Adamson S. Muula, Emmanuel Rudatsikira, Seter Siziya
Prevalence And Predictors Of Smoking In A Mining Town In Kitwe, Zambia: A 2011 Population-Based Survey, Cosmas Zyaambo, Olesegun Babaniyi, Peter Songolo, Adamson S. Muula, Emmanuel Rudatsikira, Seter Siziya
Faculty Publications
Smoking is one of the major preventable causes of death and non-communicable diseases which include hypertension, cardiovascular diseases and cancers. The aim of the study is to establish prevalence and predictors of smoking so that interventions specific to these communities can be executed to prevent smoking. A cross sectional study was conducted using a modified World Health Organizations Global Non Communicable Diseases (NCD) Surveillance Initiative NCD-STEPs 1 and 2. Multivariate logistic regression was used to examine the determinants of tobacco smoking. A total of 1627 individuals participated in the survey, of which 42.3% were males. About half of the participants …
Interventions For Improving Nutrition And Physical Activity Behaviors In Adult African American Populations: A Systematic Review, January 2000 Through December 2011, Jennifer Lemacks, Brittny A. Wells, Jasminka Z. Ilich, Penny A. Ralston
Interventions For Improving Nutrition And Physical Activity Behaviors In Adult African American Populations: A Systematic Review, January 2000 Through December 2011, Jennifer Lemacks, Brittny A. Wells, Jasminka Z. Ilich, Penny A. Ralston
Faculty Publications
Introduction The incidence of preventable chronic diseases is disproportionally high among African Americans and could be reduced through diet and physical activity interventions. Our objective was to systematically review the literature on clinical outcomes of diet and physical activity interventions conducted among adult African American populations in the United States. Methods We used the Preferred Reporting Items for Systematic Review and Meta Analysis construct in our review. We searched Medline (PubMed and Ovid), Cochrane, and DARE databases and restricted our search to articles published in English from January 2000 through December 2011. We included studies of educational interventions with clinically …
Herbert Hoover And Belgian Relief, Albert Winkler
Herbert Hoover And Belgian Relief, Albert Winkler
Faculty Publications
Herbert Hoover was an orphan, who retained great empathy for the weak and hungry his entire life. Working without pay, he organized and administered Belgian Relief starting in 1914 to get food to ten million Belgians and Frenchmen behind German lines. His efforts doubtlessly saved hundreds of thousands from starvation. This was only the starting point in his career as the "Great Humanitarian." He got food to Germany at the end of both world wars, aided Russia in their great famine, and reportedly got food to hundreds of millions of people in his lengthy career. No one has ever done …
Correlates Of Diarrhoea Among Children Below The Age Of 5 Years In Sudan, Seter Siziya, Adamson S. Muula, Emmanuel Rudatsikira
Correlates Of Diarrhoea Among Children Below The Age Of 5 Years In Sudan, Seter Siziya, Adamson S. Muula, Emmanuel Rudatsikira
Faculty Publications
Background
The Millennium Development Goals recognise child health and survival as an important socio-development issue.
Objectives
To determine the correlates of diarrhoea among children aged below 5 years in north Sudan.
Methods
We conducted secondary data analysis of the Sudan Multiple Cluster Indicators Survey II.
Results
Altogether, 23,295 children were included in the survey. Half (50.0%) of the children were males, and 22.5% of them were of age less than one year. Boys were 3% (p=0.044) more likely to have diarrhoea compared to girls. Compared with the oldest age group (48–59 months), children less than 6 months of age and …
Dissemination Of Bloodmeal Acquired Rickettsia Felis In Cat Fleas, Ctenocephalides Felis, Chutima Thepparit, Supanee Hirunkanokpun, Vsevolod L. Popov, Lane D. Foil, Kevin R. Macaluso
Dissemination Of Bloodmeal Acquired Rickettsia Felis In Cat Fleas, Ctenocephalides Felis, Chutima Thepparit, Supanee Hirunkanokpun, Vsevolod L. Popov, Lane D. Foil, Kevin R. Macaluso
Faculty Publications
Background: Cat fleas, Ctenocephalides felis, are known biological vectors for Rickettsia felis. Rickettsial transmission can be vertical via transovarial transmission within a flea population, as well as horizontal between fleas through a bloodmeal. The previously undescribed infection kinetics of bloodmeal-acquired R. felis in cat fleas provides insight into the R. felis-flea interaction. Findings. In the present study, dissemination of R. felis in previously uninfected cat fleas fed an R. felis-infected bloodmeal was investigated. At weekly intervals for 28 days, rickettsial propagation, accumulation, and dissemination in gut epithelial cells, specifically in the hindgut and the specialized cells in the neck region …
Cultural Aspects Of Latino Early Childhood Obesity, Lauren Clark, Susan L. Johnson, Mary E. O'Connor, Jane H. Lassetter
Cultural Aspects Of Latino Early Childhood Obesity, Lauren Clark, Susan L. Johnson, Mary E. O'Connor, Jane H. Lassetter
Faculty Publications
The problem of Latino childhood obesity is well known, and experts agree that the sooner it is addressed in a child’s life, the better. Strong evidence from nationwide studies suggests that obesity begins in infancy for Mexican Americans. National data demonstrate the dramatic increase in weight-for-recumbent length above the 95th percentile (using the NCHS growth chart) among Mexican American children between National Health and Nutrition Examination Survey (NHANES) and the Third National Health and Nutrition Examination Survey (NHANES III) (Ogden et al., 2006). High rates of childhood obesity affect the long-term health potential of children, since childhood obesity tracks into …
History Of Nutrient Inputs To The Northeastern United States, 1930–2000, Rebecca L. Hale, Joseph H. Hoover, Wilfred M. Wollheim, Charles J. Vorosmarty
History Of Nutrient Inputs To The Northeastern United States, 1930–2000, Rebecca L. Hale, Joseph H. Hoover, Wilfred M. Wollheim, Charles J. Vorosmarty
Faculty Publications
Humans have dramatically altered nutrient cycles at local to global scales. We examined changes in anthropogenic nutrient inputs to the northeastern United States (NE) from 1930 to 2000. We created a comprehensive time series of anthropogenic N and P inputs to 437 counties in the NE at 5 year intervals. Inputs included atmospheric N deposition, biological N2 fixation, fertilizer, detergent P, livestock feed, and human food. Exports included exports of feed and food and volatilization of ammonia. N inputs to the NE increased throughout the study period, primarily due to increases in atmospheric deposition and fertilizer. P inputs increased until …
Lead Uptake In Diverse Plant Families: A Study Applying X-Ray Absorption Near Edge Spectroscopy, Gudrun L. Bovenkamp, Alexander Prange, Wolfgang Schumacher, Kyungmin Ham, Aaron P. Smith, Josef Hormes
Lead Uptake In Diverse Plant Families: A Study Applying X-Ray Absorption Near Edge Spectroscopy, Gudrun L. Bovenkamp, Alexander Prange, Wolfgang Schumacher, Kyungmin Ham, Aaron P. Smith, Josef Hormes
Faculty Publications
The chemical environment of lead in roots and leaves of plants from four different plant families and a lichen from a former lead mining site in the Eifel Mountains in Germany was determined by Pb L3-edge XANES measurements using solid reference compounds and also aqueous solutions of different ionic strength simulating the plant environment. Pb2+ ions in the plants were found to have two major coordinations, one with nine oxygen atoms in the first coordination shell similar to outer-sphere complexation and a second coordination with just three oxygen atoms similar to inner-sphere complexation. This can be interpreted assuming that lead …
Changes In Plasma Melanocyte-Stimulating Hormone, Acth, Prolactin, Gh, Lh, Fsh, And Thyroid-Stimulating Hormone In Response To Injection Of Sulpiride, Thyrotropin-Releasing Hormone, Or Vehicle In Insulin-Sensitive And -Insensitive Mares, N. Arana Valencia, D. L. Thompson, P. B. Mitcham
Changes In Plasma Melanocyte-Stimulating Hormone, Acth, Prolactin, Gh, Lh, Fsh, And Thyroid-Stimulating Hormone In Response To Injection Of Sulpiride, Thyrotropin-Releasing Hormone, Or Vehicle In Insulin-Sensitive And -Insensitive Mares, N. Arana Valencia, D. L. Thompson, P. B. Mitcham
Faculty Publications
Six insulin-sensitive and 6 insulin-insensitive mares were used in a replicated 3 by 3 Latin square design to determine the pituitary hormonal responses (compared with vehicle) to sulpiride and thyrotropin-releasing hormone (TRH), 2 compounds commonly used to diagnose pituitary pars intermedia dysfunction (PPID) in horses. Mares were classified as insulin sensitive or insensitive by their previous glucose responses to direct injection of human recombinant insulin. Treatment days were February 25, 2012, and March 10 and 24, 2012. Treatments were sulpiride (racemic mixture, 0.01 mg/kg BW), TRH (0.002 mg/kg BW), and vehicle (saline, 0.01 mL/kg BW) administered intravenously. Blood samples were …
Resistant Starch From High Amylose Maize (Ham-Rs2) Reduces Body Fat And Increases Gut Bacteria In Ovariectomized (Ovx) Rats, Michael J. Keenan, Marlene Janes, Julina Robert, Roy J. Martin, Anne M. Raggio, Kathleen L. Mccutcheon, Christine Pelkman, Richard Tulley, M'Famara Goita, Holiday A. Durham, June Zhou, Reshani N. Senevirathne
Resistant Starch From High Amylose Maize (Ham-Rs2) Reduces Body Fat And Increases Gut Bacteria In Ovariectomized (Ovx) Rats, Michael J. Keenan, Marlene Janes, Julina Robert, Roy J. Martin, Anne M. Raggio, Kathleen L. Mccutcheon, Christine Pelkman, Richard Tulley, M'Famara Goita, Holiday A. Durham, June Zhou, Reshani N. Senevirathne
Faculty Publications
Objective: Obesity after menopause is a health concern for older females. Changes in the microbiota are likely to occur with this condition. Modifying the microbiota with a prebiotic is a plausible strategy for improving the health of menopausal females. Design and Methods: Resistant starch type 2 from high-amylose maize (HAM-RS2) was used as a prebiotic in rats in a 2 × 2 factorial study with two levels of HAM-RS2 (0 or 29.7% of weight of diet) referred to as energy control (EC) and HAM-RS2 diets, respectively; and two levels of surgery, ovariectomized (OVX) and sham. Results: In a 6-week, postsurgery …
Toxicologic Assessment Of A Commercial Decolorized Whole Leaf Aloe Vera Juice, Lily Of The Desert Filtered Whole Leaf Juice With Aloesorb, Inder Sehgal, Wallace D. Winters, Michael Scott, Andrew David, Glenn Gillis, Thaya Stoufflet, Anand Nair, Konstantine Kousoulas
Toxicologic Assessment Of A Commercial Decolorized Whole Leaf Aloe Vera Juice, Lily Of The Desert Filtered Whole Leaf Juice With Aloesorb, Inder Sehgal, Wallace D. Winters, Michael Scott, Andrew David, Glenn Gillis, Thaya Stoufflet, Anand Nair, Konstantine Kousoulas
Faculty Publications
Aloe vera, a common ingredient in cosmetics, is increasingly being consumed as a beverage supplement. Although consumer interest in aloe likely stems from its association with several health benefits, a concern has also been raised by a National Toxicology Program Report that a nondecolorized whole leaf aloe vera extract taken internally by rats was associated with intestinal mucosal hyperplasia and ultimately malignancy. We tested a decolorized whole leaf (DCWL) aloe vera, treated with activated charcoal to remove the latex portion of the plant, for genotoxicity in bacteria, acute/subacute toxicity in B6C3F1 mice, and subchronic toxicity in F344 rats. We found …
Eight Weeks Of Supplementation With A Multi-Ingredient Weight Loss Product Enhances Body Composition, Reduces Hip And Waist Girth, And Increases Energy Levels In Overweight Men And Women, Hector L. Lopez, Tim N. Ziegenfuss, Jennifer E. Hofheins, Scott M. Habowski, Shawn M. Arent Ph.D., Cscs*D, Fissn, Facsm, Fnak, Joseph P. Weir, Arny A. Ferrando
Eight Weeks Of Supplementation With A Multi-Ingredient Weight Loss Product Enhances Body Composition, Reduces Hip And Waist Girth, And Increases Energy Levels In Overweight Men And Women, Hector L. Lopez, Tim N. Ziegenfuss, Jennifer E. Hofheins, Scott M. Habowski, Shawn M. Arent Ph.D., Cscs*D, Fissn, Facsm, Fnak, Joseph P. Weir, Arny A. Ferrando
Faculty Publications
Background: Numerous natural products are marketed and sold claiming to decrease body weight and fat, but few undergo finished product-specific research demonstrating their safety and efficacy.Objective: To determine the safety and efficacy of a multi-ingredient supplement containing primarily raspberry ketone, caffeine, capsaicin, garlic, ginger and Citrus aurantium (Prograde Metabolism™ [METABO]) as an adjunct to an eight-week weight loss program.Methods: Using a randomized, placebo-controlled, double-blind design, 70 obese but otherwise healthy subjects were randomly assigned to METABO or a placebo and underwent 8 weeks of daily supplementation, a calorie restricted diet, and exercise training. Subjects were tested for changes in body …
Differential Undertaking Response Of A Lower Termite To Congeneric And Conspecific Corpses, Qian Sun, Kenneth F. Haynes, Xuguo Zhou
Differential Undertaking Response Of A Lower Termite To Congeneric And Conspecific Corpses, Qian Sun, Kenneth F. Haynes, Xuguo Zhou
Faculty Publications
Undertaking behaviour is an essential activity in social insects. Corpses are often recognized by a postmortem change in a chemical signature.Reticulitermes flavipesresponded to corpses within minutes of death. This undertaking behaviour did not change with longer postmortem time (24 h); however,R.flavipes exhibited distinctively different behaviours toward dead termites from various origins. Corpses of the congeneric species, Reticulitermes virginicus,were buried onsite by workers with a large group of soldiers guarding the burial site due to the risk of interspecific competition; while dead conspecifics, regardless of colony origin, were pulled back into the holding chamber for nutrient recycling and hygienic purposes. The …
Early Prenatal Food Supplementation Ameliorates Thenegative Association Of Maternal Stress With Birth Size In A Randomised Trial, Amy L. Frith, Ruchira T. Naved, Lars Ake Persson, Edward A. Frongillo Jr.
Early Prenatal Food Supplementation Ameliorates Thenegative Association Of Maternal Stress With Birth Size In A Randomised Trial, Amy L. Frith, Ruchira T. Naved, Lars Ake Persson, Edward A. Frongillo Jr.
Faculty Publications
Low birthweight increases the risk of infant mortality, morbidity and poor development. Maternal nutrition and stress influence birth size, but their combined effect is not known.We hypothesised that an early-invitation time to start a prenatal food supplementation programme could reduce the negative influence of prenatal maternal stress on birth size, and that effect would differ by infant sex. A cohort of 1041 pregnant women, who had delivered an infant, June 2003–March 2004, was sampled from among 3267 in the randomised controlled trial, Maternal Infant Nutritional Interventions Matlab, conducted in Matlab, Bangladesh. At 8 weeks gestation, women were randomly assigned an …
Endothelial Activation Microparticles And Inflammation Status Improve With Exercise Training In African Americans, Dianne M. Babbitt, Keith M. Diaz, Deborah L. Feairheller, Kathleen M. Sturgeon, Amanda M. Perkins, Praveen Veerabhadrappa, Sheara T. Williamson, Jan Krezschmar, Chenyi Ling, Hojun Lee, Heather Grimm, Sunny R. Thakkar
Endothelial Activation Microparticles And Inflammation Status Improve With Exercise Training In African Americans, Dianne M. Babbitt, Keith M. Diaz, Deborah L. Feairheller, Kathleen M. Sturgeon, Amanda M. Perkins, Praveen Veerabhadrappa, Sheara T. Williamson, Jan Krezschmar, Chenyi Ling, Hojun Lee, Heather Grimm, Sunny R. Thakkar
Faculty Publications
African Americans have the highest prevalence of hypertension in the world which may emanate from their predisposition to heightened endothelial inflammation. The purpose of this study was to determine the effects of a 6-month aerobic exercise training (AEXT) intervention on the inflammatory biomarkers interleukin-10 (IL-10), interleukin-6 (IL-6), and endothelial microparticle (EMP) CD62E+ and endothelial function assessed by flow-mediated dilation (FMD) in African Americans. A secondary purpose was to evaluate whether changes in IL-10, IL-6, or CD62E+ EMPs predicted the change in FMD following the 6-month AEXT intervention. A pre-post design was employed with baseline evaluation including office blood pressure, FMD, …
Transforming Synthetic Biology With Cell-Free Systems, Arnaz Ranji, Jeffrey C. Wu, Bradley Charles Bundy, Michael C. Jewett
Transforming Synthetic Biology With Cell-Free Systems, Arnaz Ranji, Jeffrey C. Wu, Bradley Charles Bundy, Michael C. Jewett
Faculty Publications
Cell-free synthetic biology offers an unprecedented level of control and freedom of design for understanding, harnessing, and expanding the capabilities of natural biological systems. Inspired by advances in synthetic biology projects in vivo, recent years have witnessed the emergence of cell-free systems not only as a testing ground for our ability to engineer and analyze biology, but also as technologies capable of efficient and scalable synthesis of complex biological products. Dominant efforts in the field include: programmable nucleic acid circuits; nanomachines; cell-free protein synthesis; cell-free metabolic engineering; and minimal cells. The goals are understanding why nature’s designs work the way …
Expansion Of Breast Cancer Stem Cells With Fibrous Scaffolds, Sheng Feng, Pang-Kuo Lo, Shou Liu, Xinfeng Liu, Hexin Chen, Qian Wang
Expansion Of Breast Cancer Stem Cells With Fibrous Scaffolds, Sheng Feng, Pang-Kuo Lo, Shou Liu, Xinfeng Liu, Hexin Chen, Qian Wang
Faculty Publications
Cancer stem cells (CSCs) are hypothesized as tumor-initiating cells within tumors and main contributors of tumor growth, metastasis and recurrence. Mammary cancer cells, MCF-7 cells, were cultured on 3D polycaprolactone (PCL) fibrous scaffolds, showing an increased proportion of CSCs. The expression of stem cell markers, including OCT3/4 and SOX2, and breast CSC-specific markers, SOX4 and CD49f, was significantly upregulated, and the mammosphere-forming capability in cells cultured on PCL fibrous scaffolds increased. The fibrous scaffolds also induced the elongation of MCF-7 cells and extended cell proliferation. The increase of CSC properties after being cultured on fibrous scaffolds was further confirmed with …
Sugar Promotes Vegetative Phase Change In Arabidopsis Thaliana By Repressing The Expression Of Mir156a And Mir156c, Li Yang, Mingli Xu, Yeonjong Koo, Jia He, R. Scott Poethig
Sugar Promotes Vegetative Phase Change In Arabidopsis Thaliana By Repressing The Expression Of Mir156a And Mir156c, Li Yang, Mingli Xu, Yeonjong Koo, Jia He, R. Scott Poethig
Faculty Publications
Nutrients shape the growth, maturation, and aging of plants and animals. In plants, the juvenile to adult transition (vegetative phase change) is initiated by a decrease in miR156. In Arabidopsis, we found that exogenous sugar decreased the abundance of miR156, whereas reduced photosynthesis increased the level of this miRNA. This effect was correlated with a change in the timing of vegetative phase change, and was primarily attributable to a change in the expression of two genes, MIR156A and MIR156C, which were found to play dominant roles in this transition. The glucose-induced repression of miR156 was dependent on the …
Corpse Management In Social Insects, Qian Sun, Xuguo Zhou
Corpse Management In Social Insects, Qian Sun, Xuguo Zhou
Faculty Publications
Undertaking behavior is an essential adaptation to social life that is critical for colony hygiene in enclosed nests. Social insects dispose of dead individuals in various fashions to prevent further contact between corpses and living members in a colony. Focusing on three groups of eusocial insects (bees, ants, and termites) in two phylogenetically distant orders (Hymenoptera and Isoptera), we review mechanisms of death recognition, convergent and divergent behavioral re-sponses toward dead individuals, and undertaking task allocation from the perspective of division of labor. Distinctly different solutions (e.g., corpse removal, burial and cannibalism) have evolved, independently, in the holometabolous hymenopterans and …
Snp Discovery And Chromosome Anchoring Provide The First Physically-Anchored Hexaploid Oat Map And Reveal Synteny With Model Species, Rebekah E. Oliver, Nicholas A. Tinker, Gerard R. Lazo, Shiaoman Chao, Eric N. Jellen, Martin L. Carson, Howard W. Rines, Donald E. Obert, Joseph D. Lutz, Irene Shackelford, Abraham B. Korol, Charlene P. Wight, Kyle M. Gardner, Jiro Hattori, Aaron D. Beattie, Åsmund Bjørnstad, J. Michael Bonman, Jean Luc Jannink, Mark E. Sorrells, Gina L. Brown-Guedira, Jennifer W. Mitchell Fetch, Stephen A. Harrison, Catherine J. Howarth, Amir Ibrahim, Frederic L. Kolb, Michael S. Mcmullen, J. Paul Murphy, Herbert W. Ohm, Brian G. Rossnagel, Weikai Yan, Kelci J. Miclaus, Jordan Hiller, Peter J. Maughan
Snp Discovery And Chromosome Anchoring Provide The First Physically-Anchored Hexaploid Oat Map And Reveal Synteny With Model Species, Rebekah E. Oliver, Nicholas A. Tinker, Gerard R. Lazo, Shiaoman Chao, Eric N. Jellen, Martin L. Carson, Howard W. Rines, Donald E. Obert, Joseph D. Lutz, Irene Shackelford, Abraham B. Korol, Charlene P. Wight, Kyle M. Gardner, Jiro Hattori, Aaron D. Beattie, Åsmund Bjørnstad, J. Michael Bonman, Jean Luc Jannink, Mark E. Sorrells, Gina L. Brown-Guedira, Jennifer W. Mitchell Fetch, Stephen A. Harrison, Catherine J. Howarth, Amir Ibrahim, Frederic L. Kolb, Michael S. Mcmullen, J. Paul Murphy, Herbert W. Ohm, Brian G. Rossnagel, Weikai Yan, Kelci J. Miclaus, Jordan Hiller, Peter J. Maughan
Faculty Publications
A physically anchored consensus map is foundational to modern genomics research; however, construction of such a map in oat (Avena sativa L., 2n = 6x = 42) has been hindered by the size and complexity of the genome, the scarcity of robust molecular markers, and the lack of aneuploid stocks. Resources developed in this study include a modified SNP discovery method for complex genomes, a diverse set of oat SNP markers, and a novel chromosome-deficient SNP anchoring strategy. These resources were applied to build the first complete, physically-anchored consensus map of hexaploid oat. Approximately 11,000 high-confidence in silico SNPs were …
Overweight And Obesity In Kaoma And Kasama Rural Districts Of Zambia: Prevalence And Correlates In 2008-2009 Population Based Surveys, Chola Besa, David Mulenga, Olesegun Babaniyi, Peter Songolo, Adamson S. Muula, Emmanuel Rudatsikira, Seter Siziya
Overweight And Obesity In Kaoma And Kasama Rural Districts Of Zambia: Prevalence And Correlates In 2008-2009 Population Based Surveys, Chola Besa, David Mulenga, Olesegun Babaniyi, Peter Songolo, Adamson S. Muula, Emmanuel Rudatsikira, Seter Siziya
Faculty Publications
Background: Overweight and obesity (overweight/obesity) is associated with hypertension. Low- and middleincome countries are experiencing an obesity epidemic. There is growing evidence that the epidemic is on the increase in urban settings of developing countries. However, there is scanty information on the magnitude of this epidemic and its correlates in rural settings. The objective of the current study was to establish levels of overweight/obesity and its correlates in rural areas of Zambia. Designing interventions based on the correlates for overweight/obesity to reduce its prevalence may in turn lead to a reduction in the prevalence of hypertension.
Methods: Cross sectional studies …
A 5-Day Method For Determination Of Soluble Silicon Concentrations In Nonliquid Fertilizer Materials Using A Sodium Carbonate-Ammonium Nitrate Extractant Followed By Visible Spectroscopy With Heteropoly Blue Analysis: Single-Laboratory Validation, Dennis Sebastian, Hugh Rodrigues, Charles Kinsey, Gaspar Korndörfer, Hamilton Pereira, Guilherme Buck, Lawrence Datnoff, Stephen Miranda, Mary Provance-Bowley
A 5-Day Method For Determination Of Soluble Silicon Concentrations In Nonliquid Fertilizer Materials Using A Sodium Carbonate-Ammonium Nitrate Extractant Followed By Visible Spectroscopy With Heteropoly Blue Analysis: Single-Laboratory Validation, Dennis Sebastian, Hugh Rodrigues, Charles Kinsey, Gaspar Korndörfer, Hamilton Pereira, Guilherme Buck, Lawrence Datnoff, Stephen Miranda, Mary Provance-Bowley
Faculty Publications
A 5-day method for determining the soluble silicon (Si) concentrations in nonliquid fertilizer products was developed using a sodium carbonate (Na 2CO3)-ammonium nitrate (NH4NO3) extractant followed by visible spectroscopy with heteropoly blue analysis at 660 nm. The 5-Day Na2CO3-NH4NO3 Soluble Si Extraction Method can be applied to quantify the plant-available Si in solid fertilizer products at levels ranging from 0.2 to 8.4% Si with an LOD of 0.06%, and LOQ of 0.20%. This Si extraction method for fertilizers correlates well with plant uptake of Si (r2 = 0.96 for a range of solid fertilizers) and is applicable to solid Si …
Pastoral Stress Management To Maximize Family Function, H. Peter Swanson
Pastoral Stress Management To Maximize Family Function, H. Peter Swanson
Faculty Publications
No abstract provided.