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The Detection Of Marine Microseismic Activity With The Cuore Tonne-Scale Cryogenic Experiment, D. Q. Adams, C. Aldunio, K. Alfonso, A. Armatol, Frank Avignone Iii, O. Azzolini, G. Bari, F. Bellini, G. Benato, M. Beretta, C. Bucci, J. Camilleri, A. Caminata, A. Campani, J. Cao, C. Capelli, S. Capelli, L. Capelli, J. Capelli, A. Caminata, Et. Al. Feb 2026

The Detection Of Marine Microseismic Activity With The Cuore Tonne-Scale Cryogenic Experiment, D. Q. Adams, C. Aldunio, K. Alfonso, A. Armatol, Frank Avignone Iii, O. Azzolini, G. Bari, F. Bellini, G. Benato, M. Beretta, C. Bucci, J. Camilleri, A. Caminata, A. Campani, J. Cao, C. Capelli, S. Capelli, L. Capelli, J. Capelli, A. Caminata, Et. Al.

Faculty Publications

Vibrations from experimental setups and the environment are a persistent source of noise for low-temperature calorimeters searching for rare events, including neutrinoless double beta (0νββ) decay or dark matter interactions. Such noise can significantly limit experimental sensitivity to the physics case under investigation. Here, we report the detection of marine microseismic vibrations using mK-scale calorimeters. This study employs a multi-device analysis correlating data from CUORE, the leading experiment in the search for 0νββ decay with mK-scale calorimeters, and the Copernicus Earth Observation program, revealing the seasonal impact of Mediterranean Sea activity on CUORE’s …


Rapid Single-Cell Measurement Of Transient Transmembrane Water Flow Under Osmotic Gradient, Hong Jiang, Jinnawat Jongkhumkrong, Y. J. Chao, Qian Wang, Guiren Wang Feb 2026

Rapid Single-Cell Measurement Of Transient Transmembrane Water Flow Under Osmotic Gradient, Hong Jiang, Jinnawat Jongkhumkrong, Y. J. Chao, Qian Wang, Guiren Wang

Faculty Publications

Aquaporins (AQPs) are critical for transmembrane water transport in response to osmotic gradients, but their gating and regulatory mechanisms remain poorly understood. A central challenge is the lack of methods to measure water flow across AQPs from individual cells with the spatiotemporal resolution and sensitivity equivalent to patch-clamp recordings of ion fluxes—a limitation stemming from the electrically silent nature of water flow. Here, we present a novel optical technique—Flow-Induced Fluorescence Increase Velocimetry (FIFIV) based on Laser-Induced Fluorescence Photobleaching Anemometry (LIFPA)—that enables direct, real-time monitoring of cytoplasmic flow induced by transmembrane water transport under osmotic pressure gradients. Using small molecular fluorescent …


Association Between Dietary Folate And Prostate Cancer Aggressiveness Among African Americans And European Americans, Lihchyun Joseph Su, Sarah O'Connor, Daniela Ramirez Aguilar, Minjae Lee, Harrison Wong, Hui-Yi Lin, Jeannette T. Bensen, James L. Mohler, Lenore Arab, Longgang Zhao, Ebonee N. Butler, Laura Farnan, Susan E. Steck Phd, Mph, Rd Feb 2026

Association Between Dietary Folate And Prostate Cancer Aggressiveness Among African Americans And European Americans, Lihchyun Joseph Su, Sarah O'Connor, Daniela Ramirez Aguilar, Minjae Lee, Harrison Wong, Hui-Yi Lin, Jeannette T. Bensen, James L. Mohler, Lenore Arab, Longgang Zhao, Ebonee N. Butler, Laura Farnan, Susan E. Steck Phd, Mph, Rd

Faculty Publications

Background: Despite the confirmed beneficial effects on preventing neural tube defects, concerns about high intakes of synthetic folate, or folic acid, in promoting cancer progression have been raised. This study evaluated the association between folate intake and prostate cancer (PCa) aggressiveness among African-American (AA) and European-American (EA) males. Methods: This study included 722 AA and 775 EA men with prostate cancer. Folate intake (dietary folate equivalent (DFE), synthetic folate, natural folate) was estimated using the National Cancer Institute Dietary History Questionnaire and detailed dietary supplement use questionnaire. Analyses included univariable comparisons of demographic and clinical characteristics of the two racial …


Discovery Of Dynamical Structures Mapping Chaotic Transport Pathways In The Earth–Moon Cr3bp, Tyler J. Kapolka, Christina E. Paljug, Robert A. Bettinger, Rachel Oliver, Bruce A. Cox, Jeremiah A. Specht Feb 2026

Discovery Of Dynamical Structures Mapping Chaotic Transport Pathways In The Earth–Moon Cr3bp, Tyler J. Kapolka, Christina E. Paljug, Robert A. Bettinger, Rachel Oliver, Bruce A. Cox, Jeremiah A. Specht

Faculty Publications

Chaos; Deterministic chaos; Earth–Moon system; Poincaré map; Quasi-chaotic; Surface of section /// For the Circular Restricted 3-Body Problem (CR3BP), the topologies present within a Poincaré map enable the extraction of useful information regarding periodic, quasi-periodic, and chaotic trajectory behavior. Aside from the prominent topologies that follow distinct concentric patterns around fixed points, indicative of the periodic and quasi-periodic motion that is often the central focus of CR3BP research, there are also many “dusty” regions on the Poincaré map that appear random without an apparent structure and are indicative of chaotic motion. This paper, for the first time in literature, identifies …


A New Highly Oxygen-Deficient And Cubic Pr3Zro8-Δ For Intermediate-Temperature Thermochemical Production Of Oxygen And Hydrogen, Jiaxin Lu, Yongliang Zhang, Luhong Chen, Yan Chen, Ke An, Yasser Shoukry, Xinfang Jin, Zhi-Hao Wang, Sai Mu, Kevin Huang Feb 2026

A New Highly Oxygen-Deficient And Cubic Pr3Zro8-Δ For Intermediate-Temperature Thermochemical Production Of Oxygen And Hydrogen, Jiaxin Lu, Yongliang Zhang, Luhong Chen, Yan Chen, Ke An, Yasser Shoukry, Xinfang Jin, Zhi-Hao Wang, Sai Mu, Kevin Huang

Faculty Publications

Two-step thermochemical cycles offer a clean route for hydrogen and oxygen production but are typically limited to high temperatures exceeding 1500 °C. Lowering operating temperatures would enable the use of alternative heat sources such as industrial waste heat. Here, we report Pr3ZrO8 as a new enabling material for efficient intermediate-temperature redox cycling, with thermal reduction at 900 °C in argon and steam oxidation at 400 °C. Pr3ZrO8 adopts a face-centered cubic structure similar to CeO2 but exhibits significantly greater oxygen deficiency, achieving average oxygen and hydrogen fluxes of 331.7 and 70.3 µmol·g-1, respectively, …


Trends In Self-Reported Responses To Nutrition Facts Labels Before And After Nutrition Labeling Policy Implementation: A Comparison Of Adults In The United States And Mexico, Jim Thrasher Ph.D., Ma, Ms, Victor Vilalobos, Dai Fang, Alejandra Jáuregui, Alejandra Contreras-Manzano, Rachel Davis Ph.D., Lana Vanderlee, Christine M. White, Rachel B. Acton, James W. Hardin, Edward A. Frongillo Jr. Ph.D., Simón Barquera, David Hammond Feb 2026

Trends In Self-Reported Responses To Nutrition Facts Labels Before And After Nutrition Labeling Policy Implementation: A Comparison Of Adults In The United States And Mexico, Jim Thrasher Ph.D., Ma, Ms, Victor Vilalobos, Dai Fang, Alejandra Jáuregui, Alejandra Contreras-Manzano, Rachel Davis Ph.D., Lana Vanderlee, Christine M. White, Rachel B. Acton, James W. Hardin, Edward A. Frongillo Jr. Ph.D., Simón Barquera, David Hammond

Faculty Publications

Background

In 2020–2021, both Mexico and the United States implemented similar, newly formatted nutrition facts labels (NFLs). Mexico simultaneously implemented front-of-package warning labels (FoPWLs), which emphasize high amounts of less healthy nutrients described in NFLs (e.g., calories, sugar, salt, trans fat, and saturated fat) to enhance consumer understanding of nutrition information.

Objectives

To evaluate these policies by comparing pre- and postpolicy trends in self-reported responses to NFLs.

Methods

Annual surveys from the adult International Food Policy Study (2018–2023) were analyzed for Mexico (n = 24,832) and the United States (n = 25,464). Outcomes included reported ease of finding …


Uranium Chemical Compound Classification Using Sub-Images And Statistical Machine Learning For Nuclear Forensics, Lee C. Lambert, Brett J. Borghetti, Abigail A. Bickley Feb 2026

Uranium Chemical Compound Classification Using Sub-Images And Statistical Machine Learning For Nuclear Forensics, Lee C. Lambert, Brett J. Borghetti, Abigail A. Bickley

Faculty Publications

Uranium particle analysis from Scanning Electron Microscope (SEM) imagery is a crucial tool in nuclear forensics. The particle morphology lexicon proposed by Tamasi et al. in J Radioanal Nucl Chem 307, 1611–1619 (2016) follows a standardized, manual identification process to identify particle morphology features. The present work seeks to mirror this methodology using computer feature selection from the scikit-image Python library rather than human classification. Using a random forest classifier, a 56% overall uranium true positive classification accuracy (a 39.6% balanced classification accuracy) was achieved on a test set outperforming a naïve (chance) model by 48%. The methodology introduced splits …


A Transcriptional Program Associated With Neurotransmission In The Living Human Brain, Alexander W. Charney, Lora E. Liharska, Eric Vornholt, Alissa Valentine, Anina Lund, Alice Hashemi, Ryan C. Thompson, Terry Lohrenz, Jessica S. Johnson, Nicole Bussola, Esther Cheng, You Jeong Park, Salman Qasim, Alisha Aristel, Lillian Wilkins, Kimia Ziafat, Hannah Silk, Lisa M. Linares, Brendan Sullivan, Claudia Feng, Beniamino Hadj-Amar Ph.D. Feb 2026

A Transcriptional Program Associated With Neurotransmission In The Living Human Brain, Alexander W. Charney, Lora E. Liharska, Eric Vornholt, Alissa Valentine, Anina Lund, Alice Hashemi, Ryan C. Thompson, Terry Lohrenz, Jessica S. Johnson, Nicole Bussola, Esther Cheng, You Jeong Park, Salman Qasim, Alisha Aristel, Lillian Wilkins, Kimia Ziafat, Hannah Silk, Lisa M. Linares, Brendan Sullivan, Claudia Feng, Beniamino Hadj-Amar Ph.D.

Faculty Publications

At the foundation of neurotransmission, and by extension at the foundation of brain function, are coordinated programs of gene expression involving many thousands of genes. These programs are poorly defined in humans because most modern studies that characterize human brain gene expression use tissue obtained in the postmortem state when neurotransmission and brain function have ceased. Here, to advance knowledge of the gene expression programs at the foundation of neurotransmission in the human brain, gene expression was characterized in 130 prefrontal cortex (PFC) samples obtained from participants of the Living Brain Project (LBP) during neurosurgical procedures in conjunction with intracranial …


Survival On Image Regression With Application To Partially Functional Distributional Representation Of Physical Activity, Rahul Ghosal, Sunwoo Emma Cho, Marcos Matabuena Feb 2026

Survival On Image Regression With Application To Partially Functional Distributional Representation Of Physical Activity, Rahul Ghosal, Sunwoo Emma Cho, Marcos Matabuena

Faculty Publications

Technological advancements in wearable devices and medical imaging often lead to high-dimensional physiological signals in the form of images or surfaces. To address these data structures, we develop a novel survival on image regression model with a specific focus on partially functional distributional representation of wearable data. The existing approaches for functional data and survival outcomes have been primarily developed for uni-dimensional functional predictors. Drawing on recent developments in distributional data analysis, we model temporally varying distributional patterns of physical activity (PA) as a partially functional distributional predictor within a semiparametric Cox model framework. We use tensor product splines to …


Environmental Chemicals And Maternal Depression During And After Pregnancy: A Scoping Review, Pengfei Guo, Yunyue Shi, Cindy Nguyen, Haoran Zhuo, Tormod Rogne, Zeyan Liew Feb 2026

Environmental Chemicals And Maternal Depression During And After Pregnancy: A Scoping Review, Pengfei Guo, Yunyue Shi, Cindy Nguyen, Haoran Zhuo, Tormod Rogne, Zeyan Liew

Faculty Publications

Purpose of Review

There is increasing evidence that several environmental exposures may pose a risk for depression, including maternal depression. We conducted a scoping review of epidemiological evidence regarding maternal exposure to environmental chemicals and perinatal depression.

Recent Findings

We searched PubMed, Embase, Web of Science, Dimensions, and Scopus, and summarized the findings from 27 articles that examined environmental chemical exposures and maternal depression. Studies of ambient air pollutants (N = 11) showed exposure to NO2 and PM10 to be most consistently associated with antenatal or postnatal depression. Studies of endocrine-disrupting chemicals, including phthalates (n = 6), …


Limit Theorems For Andrews’ Restricted Overpartitions, Tapas Bhowmik, Alex Cao, Jack Frew, John Lehman, Wei-Lun Tsai Feb 2026

Limit Theorems For Andrews’ Restricted Overpartitions, Tapas Bhowmik, Alex Cao, Jack Frew, John Lehman, Wei-Lun Tsai

Faculty Publications

The study of overpartitions in recent years has been used to great effect in various fields, including hypergeometric series, q-series identities, and mathematical physics. We investigate the limiting distributions of the number of parts in a family of overpartitions of n,  introduced by Andrews, where parts are counted with two different weights. Using Andrews’ identities and the saddle-point method, we establish two central limit theorems (CLTs) for the number of parts as n → ∞, corresponding to these weightings. We also derive explicit formulas for the mean and variance in each case.


Vegetation Enhances Nitrogen Removal In Stormwater Ponds In Coastal South Carolina, Darcy Perin, Annie Bourbonnais Feb 2026

Vegetation Enhances Nitrogen Removal In Stormwater Ponds In Coastal South Carolina, Darcy Perin, Annie Bourbonnais

Faculty Publications

Coastal development and the increase in impervious surfaces lead to greater stormwater volumes, a key contributor to nonpoint source pollution. Stormwater ponds are generally highly efficient in eliminating particle-bound nutrients, such as phosphorus, but are often much less effective at removing dissolved nutrients, like nitrogen. Excess inorganic nitrogen can lead to coastal eutrophication, harmful cyanobacterial blooms, and coastal hypoxia. However, inorganic nitrogen can be removed from the environment through several different microbially facilitated processes. This research aims to estimate the rates of nitrogen removal (i.e., by denitrification), the net N2 fluxes, and internal recycling (DNRA) across the sediment-water interface …


Intravascular Ultrasound Is More Accurate Than Angiography In Arteriovenous Vascular Access Lesions, James W. Decker, Dima Banihani, Curtis Honshideler, Saran Lotfollahzadeh, David Jasen Wu Wong, Alik Farber, Jeffrey J. Siracuse, Najia Idrees, Laura Dember, Mohammad Bader, Suvranu Ganguli, Vijaya Kolachalama, Tarek Shazly Feb 2026

Intravascular Ultrasound Is More Accurate Than Angiography In Arteriovenous Vascular Access Lesions, James W. Decker, Dima Banihani, Curtis Honshideler, Saran Lotfollahzadeh, David Jasen Wu Wong, Alik Farber, Jeffrey J. Siracuse, Najia Idrees, Laura Dember, Mohammad Bader, Suvranu Ganguli, Vijaya Kolachalama, Tarek Shazly

Faculty Publications

Background:

Conventional angiography remains the standard diagnostic modality for arteriovenous (AV) access dysfunction in hemodialysis patients, but its geometric accuracy is limited. Intravascular ultrasound (IVUS) offers superior lesion detection, yet its absolute measurement accuracy remains uncertain. Using three-dimensional (3D) printed vascular conduits as reference standards, we assessed the accuracy of IVUS versus angiography, hypothesizing that complex conduit geometry, quantified by Gaussian curvature, would exacerbate angiographic error.

Methods

Clinically relevant AV access geometries were modeled with computer-aided design (CAD) and fabricated using 3D printing. Lumen diameters were measured by contrast angiography and IVUS and compared with CAD dimensions. Conduit geometry was …


Assessing The Threat Of Southern Pine Beetle To Pitch Pine In Acadia National Park, Caroline R. Kanaskie, Mark J. Ducey, Jeff R. Garnas Feb 2026

Assessing The Threat Of Southern Pine Beetle To Pitch Pine In Acadia National Park, Caroline R. Kanaskie, Mark J. Ducey, Jeff R. Garnas

Faculty Publications

Many of the mountain summits of Acadia National Park (ACAD) are dominated by Pinus rigida (Pitch Pine). The ACAD Pitch Pine population is particularly valuable due to its position at the northernmost edge of the species’ range, its association with unique animal and plant communities, and its contribution to the aesthetics of the park. Pitch Pine is host to Dendroctonus frontalis (Southern Pine Beetle [SPB]). As the name suggests, SPB is native to the southeastern US, and can kill large numbers of healthy pines via mass-attack. With warming winters, SPB can establish and persist further north than ever before, presenting …


Albumin-Binding Domains In Therapeutic Protein Engineering: A Structural And Computational Perspective On Rational Design, Matthew Argyle, Dallin M. Chipman, Anna Claire Woolley, Bradley C. Bundy, Dennis Della Corte Feb 2026

Albumin-Binding Domains In Therapeutic Protein Engineering: A Structural And Computational Perspective On Rational Design, Matthew Argyle, Dallin M. Chipman, Anna Claire Woolley, Bradley C. Bundy, Dennis Della Corte

Faculty Publications

Therapeutic proteins face a critical pharmacokinetic challenge: rapid clearance from circulation limits their clinical efficacy. Albumin-binding domains (ABDs) offer an elegant solution by enabling therapeutic proteins to “hitchhike” on serum albumin’s favorable 19-day half-life through FcRn-mediated recycling. Clinical validation through approved therapeutics like ozoralizumab demonstrates the success of this approach, with preclinical studies showing fusion to an ABD extended half-life to 18 days. This review provides an analysis of ABD-fusion protein design, integrating structural biology, computational prediction, and rational engineering principles. We catalog the major classes of albumin-binding modalities, including bacterial three-helix bundle domains, engineered peptides, antibody-derived binders, and alternative …


Uav-Deployable Open-Source Sensor Nodes For Spatial And Temporal In Situ Water Quality Monitoring And Mapping, Matthew Burnett, Mohamed Abdelwahab, Joud N. Satme, Austin Downey, Gabriel Barahona Smith, Antonio Fonce, Jasim Imran Feb 2026

Uav-Deployable Open-Source Sensor Nodes For Spatial And Temporal In Situ Water Quality Monitoring And Mapping, Matthew Burnett, Mohamed Abdelwahab, Joud N. Satme, Austin Downey, Gabriel Barahona Smith, Antonio Fonce, Jasim Imran

Faculty Publications

Cost efficient, spatially resolved water quality monitoring is essential for managing pollution and protecting aquatic ecosystems. This study presents a low-cost (approximately USD 200), open-source, unmanned aerial vehicle (UAV)-deployable in situ sensor node for real-time assessment of surface-water conditions. The system integrates sensors for pH, turbidity, temperature, and total dissolved solids (TDSs), with onboard data logging and real-time clock (RTC) synchronization. Bench validation of the sensor package yielded mean absolute percentage errors of 1.34% for pH, 5.23% for TDS, and 0.81% for temperature, and the device operated continuously for 42 h. Field deployment demonstrated its ability to resolve spatial gradients, …


Equal Chances Or Fewer Victims? Moral Judgments In Autonomous Vehicle Dilemmas, Alexander Matros, Eren Bilen, Leonid Matros Feb 2026

Equal Chances Or Fewer Victims? Moral Judgments In Autonomous Vehicle Dilemmas, Alexander Matros, Eren Bilen, Leonid Matros

Faculty Publications

We examine the moral dilemma of how autonomous vehicles (AVs) should be programmed to act in unavoidable crash scenarios involving trade-offs between saving one life and saving many. We report results from three experimental studies that investigate individuals’ preferences over alternative AV decision rules in stylized crash scenarios. Across designs, we find robust support for a probabilistic decision rule that assigns passengers and pedestrians equal ex ante chances of survival (a 50:50 rule). This preference persists across different framings and remains salient even when additional probabilistic options are introduced.


The Structure, Pathogenesis, And Inhibition Of The P53-Mdm2 Pathway, Amanda L. Brown, Xiaoying Lian, Qian Wang Feb 2026

The Structure, Pathogenesis, And Inhibition Of The P53-Mdm2 Pathway, Amanda L. Brown, Xiaoying Lian, Qian Wang

Faculty Publications

The p53 tumor suppressor protein plays a central role in maintaining genomic stability by regulating cell cycle arrest, apoptosis, and DNA repair under cellular stress. Mouse double minute 2 (MDM2), an E3 ubiquitin ligase, negatively regulates p53 via direct binding and proteasomal degradation. Overexpression or amplification of MDM2 can disrupt this pathway and promote tumorigenesis, even in cancers with wild-type p53. This review outlines the structural features of MDM2, particularly its N-terminal hydrophobic pocket and C-terminal RING domain, and their roles in p53 regulation. We further examine the pathological effects of MDM2 dysregulation and SNPs linked to increased cancer risk. …


Understanding The 2016–2018 Freshening Dynamics Of The Beaufort Gyre Through Observations And Model Reanalysis, Christina Gregory, Ganesh Gopalakrishnan, Bulusu Subrahmanyam Feb 2026

Understanding The 2016–2018 Freshening Dynamics Of The Beaufort Gyre Through Observations And Model Reanalysis, Christina Gregory, Ganesh Gopalakrishnan, Bulusu Subrahmanyam

Faculty Publications

The Beaufort Gyre (BG) in the Arctic Ocean has experienced rapid changes in losing extensive amounts of sea-ice and undergoing freshening over the past few decades. In this study, we highlight important recent changes in BG’s surface circulation, and its impact on freshwater (FW) fluxes and freshwater content (FWC) and draw attention to the critical importance of continuous monitoring of BG dynamics. Using satellite observations of the upper ocean state and ocean and atmospheric reanalysis, here we attempt to understand the anomalous behavior of BG dynamics over the past few decades. In recent years, atmospheric forcings increasingly influenced important judications …


Ecologic Factors Contributing To West Nile Virus Hyperendemicity In Central South Carolina: An Integrated Vector–Human–Environmental Study, Elba S. Fridriksson, Ahayla Muraleedharan, Kyndall C. Dye-Braumuller, Madeleine M. Meyer, Kia Zellars, Hiuxuan Li, Melissa S. Nolan Ph.D., Mph Feb 2026

Ecologic Factors Contributing To West Nile Virus Hyperendemicity In Central South Carolina: An Integrated Vector–Human–Environmental Study, Elba S. Fridriksson, Ahayla Muraleedharan, Kyndall C. Dye-Braumuller, Madeleine M. Meyer, Kia Zellars, Hiuxuan Li, Melissa S. Nolan Ph.D., Mph

Faculty Publications

West Nile virus (WNV) is an endemic arboviral infection in the United States that has undergone phyloge-netic evolution since its introduction 25 years ago. An integrated vector–human–pathogen study was conducted in the summer of 2023 to unearth contemporary Culex quinquefasciatus habitat patterns and human transmission spillover foci in South Carolina, a state with historically little WNV data. A serosurvey revealed WNV seroprevalence 10 times the national average (22% versus 2%, respectively), with unusual epidemiologic risk factors. Female Culex quinquefas-ciatus WNV positivity was low (2.7%), with viral phylogenetics 100% homologous to the WN02 clade. Mosquito vectors clustered in affluent urban neighborhoods …


Construction Project Performance Research: A Bibliometric, Scientometric, And Qualitative Review (1989–2023), Abdelnaser Abdelhameed, Mohamed S. Yamany, Ahmed Abdelaty, Emad Elbeltagi Feb 2026

Construction Project Performance Research: A Bibliometric, Scientometric, And Qualitative Review (1989–2023), Abdelnaser Abdelhameed, Mohamed S. Yamany, Ahmed Abdelaty, Emad Elbeltagi

Faculty Publications

Despite the significant increase in publications on construction project performance (CPP), there is a deficiency of research that rigorously assesses and synthesizes previous studies to delineate the field’s development, themes, and research gaps. This article employs quantitative and qualitative methodologies to critically evaluate studies on CPP published over the last three decades and indexed in the Scopus database. The quantitative approach includes bibliometric searches and scientometric analyses to assess the extent of research interest and achievements. The qualitative methodology aims to conduct thorough content analysis to classify existing material based on prevalent themes. The results demonstrate an exponential growth of …


Boronate Esters For The Binding And Detection Of Low Molecular Weight Volatile Amines, Xiaoning Li, James Boyt, Steven Sloope, Luke T. Lackovic, Mark D. Smith, James J. Lavingne Feb 2026

Boronate Esters For The Binding And Detection Of Low Molecular Weight Volatile Amines, Xiaoning Li, James Boyt, Steven Sloope, Luke T. Lackovic, Mark D. Smith, James J. Lavingne

Faculty Publications

Conjugated thiophene-based diboronate esters, 1–4, were synthesized to investigate how substituents on catechol alter the Lewis acidity and accessibility to boron, and influence binding interactions with low molecular weight Lewis basic amines. Crystallographic analysis indicated that both boron centres bind analyte and that Lewis base coordination induces deplanarization of the conjugated system. Spectroscopic studies demonstrate that amine binding disrupts conjugation, producing distinct and reproducible optical responses that depend on analyte basicity and structure, with association constants in organic solvent ranging from 103 to 106 M−1. Quantitative binding analyses indicate strong negative cooperativity between the two boron …


Dynamical Analysis Of A Stochastic $Sei_{U}I_{R}Rs$ Epidemic Model With Vaccination And Log-Normal Ornstein-Uhlenbeck Process, Qun Liu Feb 2026

Dynamical Analysis Of A Stochastic $Sei_{U}I_{R}Rs$ Epidemic Model With Vaccination And Log-Normal Ornstein-Uhlenbeck Process, Qun Liu

Faculty Publications

In this study, we develop and investigate a stochastic $SEI_{u}I_{r}RS$ (Susceptible-Exposed-Undetected infected-Detected infected-Recovered-Susceptible) epidemic model with vaccination of newborns and the disease transmission rate driven by a log-normal Ornstein-Uhlenbeck process. By establishing a series of Lyapunov functions, we derive sufficient conditions for persistence in the mean of the disease in the long term under the condition $\mathcal{R}_{0}>1$ and these criteria are applied to guarantee the existence of an invariant probability measure of the stochastic system. Subsequently, we also derive sufficient conditions for eradication of the disease when the parameters $\mathcal{R}_{0}< 1$ and $\mathcal{R}_{0}^{E}< 1$. Finally, two numerical examples are given to confirm the theoretical results. This work can help us implement interventions to regulate the disease dynamics.


Impact Of Iron-Bearing Fillers On The Mechanical Strength And Chemical Stability Of Magnesium Potassium Phosphate Matrices Incorporating Rhenium, Sergey Sayenko, Volodymyr Shkuropatenko, Hans Conrad Zur Loye, Petr Vecernik, Monika Kiselova, Vlastislav Kašpar, Vlastimil Miller, Petr Bezdicka, Jan Šubrt, Petra Ecorchard, Natalija Murafa, Iva Milisavljevic, Scott T. Misture Feb 2026

Impact Of Iron-Bearing Fillers On The Mechanical Strength And Chemical Stability Of Magnesium Potassium Phosphate Matrices Incorporating Rhenium, Sergey Sayenko, Volodymyr Shkuropatenko, Hans Conrad Zur Loye, Petr Vecernik, Monika Kiselova, Vlastislav Kašpar, Vlastimil Miller, Petr Bezdicka, Jan Šubrt, Petra Ecorchard, Natalija Murafa, Iva Milisavljevic, Scott T. Misture

Faculty Publications

We report on the study of the immobilization process of non-radioactive rhenium (Re), a chemical analogue of technetium-99 (99Tc), in compounds based on magnesium potassium phosphate (MKP), as well as the possibility of enhancing their properties with iron-bearing additives/fillers. Powdered Re2O7 was used as the initial Re-containing source. Because of the solubility and high leachability of Tc (VII), which is also volatile at high temperatures, its immobilization for long-term storage and disposal poses a serious challenge to researchers. Taking this into account, low-temperature stabilization technology based on MKP, a cementitious material, is currently considered promising. We prepared experimental …


Future Trends In Cybersecurity: A Meta-Review, Yara Mohammed, Manar Alsaid, Gahangir Hossain Feb 2026

Future Trends In Cybersecurity: A Meta-Review, Yara Mohammed, Manar Alsaid, Gahangir Hossain

Faculty Publications

The increasing importance of cybersecurity in protecting digital assets, data and infrastructures necessitates a reevaluation of research priorities within the discipline. As of today, numerous emerging cybersecurity topics are gaining significant importance in both academic research and industry applications. To identify recent trends in cybersecurity topics, this study extracts scholarly articles from two prestigious academic databases, the ACM Digital Library, and Google Scholar, covering the period from early 2015 to late 2024.Through a systematic identification of trends and focal points in cybersecurity research, a comprehensive analysis is facilitated, including Latent Dirichlet Allocation (LDA), Biterm Topic Modeling (BTM), keyword frequencies, and …


Patient-Specific Lumped-Parameter Model For Quantifying Vessel-Specific Remodeling And Predicting Right Ventricular Function In Pulmonary Hypertension, Christopher G. Lechuga, Amirreza Kachabi, Mitchel J. Colebank, Claudia E. Korcarz, Farhan Raza Jan 2026

Patient-Specific Lumped-Parameter Model For Quantifying Vessel-Specific Remodeling And Predicting Right Ventricular Function In Pulmonary Hypertension, Christopher G. Lechuga, Amirreza Kachabi, Mitchel J. Colebank, Claudia E. Korcarz, Farhan Raza

Faculty Publications

Purpose: Pulmonary hypertension (PH) is a heterogeneous disease with patient-specific variability and vessel-specific remodeling, which eventually lead to right ventricular (RV) failure. The gold standard for RV assessment—pressure–volume (PV) loop acquisition—is invasive and limited to specialized settings. This study aims to develop a patient-specific lumped-parameter model that quantifies vessel-specific remodeling and simulates RV PV loops across PH phenotypes using routine clinical data.

Methods: A lumped-parameter model was calibrated using right heart catheterization and echocardiography data. Model agreement was assessed by R2 values for pressure and flow goodness-of-fit, and model-derived hemodynamic metrics were comparedwith clinical values. A dimensionality reduction approach was …


Characterization Of Ru(Ii) Polypyridyl Photosensitizers Bound To Tio2 Supports Through A New Covalent Metal-Ester Bonding Motif, D. M. S. C. Dissanayake, Christopher T. Lebarron, Laura C. Maybach, Joseph J. Kuchta Iii, Seyyedamirhossein Hosseini, Aaron K. Vannucci Jan 2026

Characterization Of Ru(Ii) Polypyridyl Photosensitizers Bound To Tio2 Supports Through A New Covalent Metal-Ester Bonding Motif, D. M. S. C. Dissanayake, Christopher T. Lebarron, Laura C. Maybach, Joseph J. Kuchta Iii, Seyyedamirhossein Hosseini, Aaron K. Vannucci

Faculty Publications

The development of photoelectrochemical (PEC) devices involves the attachment of molecular photosensitizers onto solid supports. Particularly significant to this work are PECs that rely on ruthenium-based photosensitizers on high band gap metal oxide (MOx) supports. In this study, we have explored a new ester binding motif (MOx-ester) to covalently attach a ruthenium polypyridyl photosensitizer to TiO2. This new MOx-ester photoanode is compared to the traditional photoanodes that utilize acid/base binding groups to attach the molecular Ru sensitizers to TiO2. The new MOx-ester binding motif is characterized by cyclic voltammetry UV-Vis, solid state 13C NMR, and …


Spline-Based Factor-Graph Optimization With High-Grade Inertial Sensors, Kyle Leland, Clark N. Taylor, David Woodburn, Randal Beard Jan 2026

Spline-Based Factor-Graph Optimization With High-Grade Inertial Sensors, Kyle Leland, Clark N. Taylor, David Woodburn, Randal Beard

Faculty Publications

Inertial measurement units (IMUs) are central to global navigation satellite system-based and alternative navigation solutions. This paper combines three lines of research to explore a novel methodology for using inertial sensors: factor graphs, spline-based trajectory estimation, and high-grade inertial sensing. Spline-based factor-graph trajectory estimation is increasingly used in the literature, especially for asynchronous or high-rate sensors. However, prior models neglect the impact of the Earth’s rotation, which is significant for high-grade IMUs. We extend spline-based factor graphs to incorporate accelerometer and gyroscope models that account for the Earth’s rotation. We apply this approach to simulated data from high-grade inertial sensors …


The Age And Composition Of The Voyager Seamounts: Evidence For A Long-Lived Marquesas Mantle Source, Andrea Balbas, Hannah Paradis, Kevin Konrad, Valerie A. Finlayson, Michael Bizimis, Stephanie Anderson, Christopher Kelley, Nicole A. Raineault, Beth N. Orcutt Jan 2026

The Age And Composition Of The Voyager Seamounts: Evidence For A Long-Lived Marquesas Mantle Source, Andrea Balbas, Hannah Paradis, Kevin Konrad, Valerie A. Finlayson, Michael Bizimis, Stephanie Anderson, Christopher Kelley, Nicole A. Raineault, Beth N. Orcutt

Faculty Publications

We present new observations on the dynamics and locations of deep mantle reservoirs derived from the ages and compositions of Voyager Seamount Chain lava flows. The previously unexplored Voyager Seamount Chain trends NW–SE between the Mid-Pacific Mountains and the Northwestern Hawaiian Ridge. Volcanic samples were recovered from the chain during the Ocean Exploration Trust expedition NA134. The lava flows are alkalic to highly alkalic in composition. Ages ranged from 81 to 86 Ma (n = 8), with the oldest ages in the NW and an age-progression toward the SE. The Voyager age-progression continues southward through the Northern Line Islands …


High Frobenius Pushforwards Generate The Bounded Derived Category, Matthew R. Ballard, Srikanth B. Iyengar, Pat Lank, Alapan Mukhopadhyay, Josh Pollitz Jan 2026

High Frobenius Pushforwards Generate The Bounded Derived Category, Matthew R. Ballard, Srikanth B. Iyengar, Pat Lank, Alapan Mukhopadhyay, Josh Pollitz

Faculty Publications

This work concerns generators for the bounded derived category of coherent sheaves over a noetherian scheme X of prime characteristic. The main result is that when the Frobenius map on X is finite, for any compact generator G of D(X) the Frobenius pushforward Fe*G generates the bounded derived category whenever pe is larger than the codepth of X, an invariant that is a measure of the singularity of X. The conclusion holds for all positive integers e when X is locally complete intersection. The question of when one can take G = …