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One Planet: One Health. A Call To Support The Initiative On A Global Science-Policy Body On Chemicals And Waste, Werner Brack, Damia Barcelo Culleres, Alistair B.A. Boxall, Helene Budzinski, Sara Castiglioni, Adrian Covaci, Valeria Dulio, Beate I. Escher, Peter Fantke, Faith Kandie, Despo Fatta-Kassinos, Felix J. Hernandez, Klara Hilscherova, Juliane Hollender, Henner Hollert, Annika Jahnke, Barbara Kasprzyk-Hordern, Stuart J. Khan, Andreas Kortenkamp, Klaus Kuemmerer, Brice Lalonde, Marja H. Lamoree, Yves Levi, Pablo Antonio Lara Martin, Cassiana C. Montagner, Christian Mougin, Titus Msagati, Joerg Oehlmann, Leo Posthuma, Malcolm Reid, Martin Reinhard, Susan D. Richardson, Et. Al. Mar 2022

One Planet: One Health. A Call To Support The Initiative On A Global Science-Policy Body On Chemicals And Waste, Werner Brack, Damia Barcelo Culleres, Alistair B.A. Boxall, Helene Budzinski, Sara Castiglioni, Adrian Covaci, Valeria Dulio, Beate I. Escher, Peter Fantke, Faith Kandie, Despo Fatta-Kassinos, Felix J. Hernandez, Klara Hilscherova, Juliane Hollender, Henner Hollert, Annika Jahnke, Barbara Kasprzyk-Hordern, Stuart J. Khan, Andreas Kortenkamp, Klaus Kuemmerer, Brice Lalonde, Marja H. Lamoree, Yves Levi, Pablo Antonio Lara Martin, Cassiana C. Montagner, Christian Mougin, Titus Msagati, Joerg Oehlmann, Leo Posthuma, Malcolm Reid, Martin Reinhard, Susan D. Richardson, Et. Al.

Faculty Publications

The chemical pollution crisis severely threatens human and environmental health globally. To tackle this challenge the establishment of an overarching international science–policy body has recently been suggested. We strongly support this initiative based on the awareness that humanity has already likely left the safe operating space within planetary boundaries for novel entities including chemical pollution. Immediate action is essential and needs to be informed by sound scientific knowledge and data compiled and critically evaluated by an overarching science–policy interface body. Major challenges for such a body are (i) to foster global knowledge production on exposure, impacts and governance going beyond …

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Madfam: Microarchitectural Data Framework And Methodology, Tor J. Langehaug, Scott R. Graham, Christine M. Schubert Kabban, Brett J. Borghetti Mar 2022

Madfam: Microarchitectural Data Framework And Methodology, Tor J. Langehaug, Scott R. Graham, Christine M. Schubert Kabban, Brett J. Borghetti

Faculty Publications

In the aftermath of Spectre and Meltdown researchers have proposed a variety of attack detection solutions by applying machine learning to data collected from hardware performance monitoring units. Although many microarchitectural attack detection systems provide high-accuracy detection results, the behavior of the underlying data collection mechanisms is not well described or understood. This research introduces the MicroArchitectural Data Framework And Methodology (MADFAM) to prescribe a systematic approach to collecting and preserving the information available in sequences of microarchitectural data. The proposed framework focuses on hardware performance counters (HPCs) as the primary data source. HPC configuration is complex, which makes it …

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Search For Lepton Flavor Violation In ϒ(3S) → E±Μ∓, J. P. Lees, V. Tisserand, A. Palano, G. Eigen, D. N. Brown, Yu. G. Kolomensky, M. Fritsch, H. Koch, T. Schroeder, R. Cheaib, C. Hearty, T. S. Mattison, J. A. Mckenna, R. Y. So, V. E. Blinov, A. R. Buzykaev, V. P. Druzhinin, V. B. Golubev, E. A. Kozyrev, Milind Purohit, Jeffery R. Wilson, Et. Al. Mar 2022

Search For Lepton Flavor Violation In ϒ(3S) → E±Μ∓, J. P. Lees, V. Tisserand, A. Palano, G. Eigen, D. N. Brown, Yu. G. Kolomensky, M. Fritsch, H. Koch, T. Schroeder, R. Cheaib, C. Hearty, T. S. Mattison, J. A. Mckenna, R. Y. So, V. E. Blinov, A. R. Buzykaev, V. P. Druzhinin, V. B. Golubev, E. A. Kozyrev, Milind Purohit, Jeffery R. Wilson, Et. Al.

Faculty Publications

We report on the first search for electron-muon lepton flavor violation (LFV) in the decay of a b quark and b antiquark bound state. We look for the LFV decay ϒ(3S) → e ± μ∓ in a sample of 118 million ϒ(3S) mesons from 27 fb−1 of data collected with the BABAR detector at the SLAC PEP-II e+e− collider operating with a 10.36 GeV center-of-mass energy. No evidence for a signal is found, and we set a limit on the branching fraction B[ϒ(3S) → e ± μ∓]< 3.6 × 10−7 …

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Refugee Food Insecurity & Technology: Surfacing Experiences Of Adaptation, Navigation, Negotiation And Sharing, Reem Talhouk, Kyle Montague, Hala Ghattas, Vera Araujo-Soares, Balsam Ahmad, Madeline Balaam Mar 2022

Refugee Food Insecurity & Technology: Surfacing Experiences Of Adaptation, Navigation, Negotiation And Sharing, Reem Talhouk, Kyle Montague, Hala Ghattas, Vera Araujo-Soares, Balsam Ahmad, Madeline Balaam

Faculty Publications

With the Syrian crisis still ongoing, 91% of Syrian refugee families in Lebanon do not have adequate access to safe and sufficient food. There has been a drive for technological innovation in humanitarian food assistance. To further inform such innovation, we used an Experience-Centred Design approach to gain a holistic understanding of the experiences of refugee food insecurity and how refugees envision technologies can support them. Design engagements with 13 women in an informal refugee settlement in Lebanon were conducted. The findings presented in this paper highlight that coping with food insecurity consists of experiences of adaptation, navigation, negotiation and …

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Peak Chlorophyll A Concentrations In The Lower Mississippi River From 1997 To 2018, R. Eugene Turner, Charles S. Milan, Erick M. Swenson, James M. Lee Mar 2022

Peak Chlorophyll A Concentrations In The Lower Mississippi River From 1997 To 2018, R. Eugene Turner, Charles S. Milan, Erick M. Swenson, James M. Lee

Faculty Publications

Large and turbid rivers have varying temperatures, light conditions, nutrient availability, and nutrient ratios that may affect phytoplankton communities and occur within a changing world of point and nonpoint source nutrient loadings. We investigated how these physical and chemical factors affect Chlorophyll a (Chl a) concentrations in the Mississippi River, the largest river in North America, by sampling 878 times from February 1997 to December 2018 near its terminus at Baton Rouge, Louisiana. We hypothesized that nutrient concentrations and ratios were significant factors limiting phytoplankton biomass accumulations in this turbid river. The Chl a concentrations were in the "poor" water …

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Prediction Of Pressure Increase During Waste Water Injection To Prevent Seismic Events, Lu Jin, Andrew K. Wojtanowicz, Jun Ge Mar 2022

Prediction Of Pressure Increase During Waste Water Injection To Prevent Seismic Events, Lu Jin, Andrew K. Wojtanowicz, Jun Ge

Faculty Publications

A considerable increase of seismicity has occurred in the USA in the last decade (2009–2020) with an annual average of 345 M3+ earthquakes. Numerous field cases have shown that excessive well pressure due to a high injection rate may have triggered seismic events. This study defines conditions for inducing a seismic event by excessive injection in the well’s pressure that may cause geomechanical damage to the rock. Introduced here is an analytical model and method for predicting pressure increase during injection of produced water contaminated with oil. The model calculates time-dependent advancement of the captured oil saturation causing the well’s …

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Gaia Gral: Gaia Dr2 Gravitational Lens Systems. Vii. Xmm-Newton Observations Of Lensed Quasars, Thomas Connor, Daniel Stern, Alberto Krone-Martins, S. G. Djorgovski, Matthew J. Graham Mar 2022

Gaia Gral: Gaia Dr2 Gravitational Lens Systems. Vii. Xmm-Newton Observations Of Lensed Quasars, Thomas Connor, Daniel Stern, Alberto Krone-Martins, S. G. Djorgovski, Matthew J. Graham

Faculty Publications

We present XMM-Newton X-ray observations of nine confirmed lensed quasars at 1 less than or similar to z less than or similar to 3 identified by the Gaia Gravitational Lens program. Eight systems are strongly detected, with 0.3-8.0 keV fluxes F (0.3-8.0) greater than or similar to 5 x10(-14) erg cm(-2) s(-1). Modeling the X-ray spectra with an absorbed power law, we derive power-law photon indices and 2-10 keV luminosities for the eight detected quasars. In addition to presenting sample properties for larger quasar population studies and for use in planning for future caustic-crossing events, we also identify three quasars …

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A Multiparameter Degeneracy In Microlensing Events With Extreme Finite Source Effects, Samson A. Johnson, Matthew T. Penny, B. Scott Gaudi Mar 2022

A Multiparameter Degeneracy In Microlensing Events With Extreme Finite Source Effects, Samson A. Johnson, Matthew T. Penny, B. Scott Gaudi

Faculty Publications

For microlenses with sufficiently low mass, the angular radius of the source star can be much larger than the angular Einstein ring radius of the lens. For such extreme finite source effect (EFSE) events, finite source effects dominate throughout the duration of the event. Here, we demonstrate and explore a continuous degeneracy between multiple parameters of such EFSE events. The first component in the degeneracy arises from the fact that the directly observable peak change of the flux depends on both the ratio of the angular source radius to the angular Einstein ring radius and the fraction of the baseline …

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The Global Virome In One Network (Virion): An Atlas Of Vertebrate-Virus Associations, Colin J. Carlson, Rory J. Gibb, Gregory F. Albery, Liam Brierley, Ryan P. Connor, Tad Dallas, Evan A. Eskew, Anna C. Fagre, Maxwell J. Farrell, Hannah K. Frank, Renata L. Muylaert, Timothée Poisot, Angela L. Rasmussen, Sadie J. Ryan, Stephanie N. Seifert Mar 2022

The Global Virome In One Network (Virion): An Atlas Of Vertebrate-Virus Associations, Colin J. Carlson, Rory J. Gibb, Gregory F. Albery, Liam Brierley, Ryan P. Connor, Tad Dallas, Evan A. Eskew, Anna C. Fagre, Maxwell J. Farrell, Hannah K. Frank, Renata L. Muylaert, Timothée Poisot, Angela L. Rasmussen, Sadie J. Ryan, Stephanie N. Seifert

Faculty Publications

Data that catalogue viral diversity on Earth have been fragmented across sources, disciplines, formats, and various degrees of open sharing, posing challenges for research on macroecology, evolution, and public health. Here, we solve this problem by establishing a dynamically maintained database of vertebrate-virus associations, called The Global Virome in One Network (VIRION). The VIRION database has been assembled through both reconciliation of static data sets and integration of dynamically updated databases. These data sources are all harmonized against one taxonomic backbone, including metadata on host and virus taxonomic validity and higher classification; additional metadata on sampling methodology and evidence strength …

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Fourth-Order Adjoint Sensitivity And Uncertainty Analysis Of An Oecd/Nea Reactor Physics Benchmark: Ii. Computed Response Uncertainties, Ruixian Fang, Dan Gabriel Cacuci Mar 2022

Fourth-Order Adjoint Sensitivity And Uncertainty Analysis Of An Oecd/Nea Reactor Physics Benchmark: Ii. Computed Response Uncertainties, Ruixian Fang, Dan Gabriel Cacuci

Faculty Publications

This work quantifies the impact of the most important 4th-order sensitivities of the leakage response of a polyethylene-reflected plutonium (PERP) reactor physics benchmark with respect to the benchmark’s 180 group-averaged microscopic total cross sections, on the expected value, variance and skewness of the benchmark’s leakage response. This work shows that, as the standard deviations of the cross sections increase, the contributions of the 4th-order sensitivities to the response’s expected value and variance become significantly larger than the corresponding contributions stemming from the 1st-, 2nd- and 3rd-order sensitivities. Considering a uniform 5% relative standard deviation for all microscopic total cross sections, …

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Correction To: Optimal Location For Renewable Gas Production And Distribution Facilities: Resource Planning And Management (Bioenergy Research, (2022), 15, 1, (650-666), 10.1007/S12155-021-10278-0), Bhaba R. Sarker, Bingqing Wu, Krishna P. Paudel Mar 2022

Correction To: Optimal Location For Renewable Gas Production And Distribution Facilities: Resource Planning And Management (Bioenergy Research, (2022), 15, 1, (650-666), 10.1007/S12155-021-10278-0), Bhaba R. Sarker, Bingqing Wu, Krishna P. Paudel

Faculty Publications

In the "A Numerical Illustration" section, the mathematical expression in matrix format were mistakenly presented. The correct form are as follows.

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Event-Triggered Control For Linear Time-Varying Systems Using A Positive Systems Approach, Frederic Mazenc, Michael Malisoff, Corina Barbalata, Zhong Ping Jiang Mar 2022

Event-Triggered Control For Linear Time-Varying Systems Using A Positive Systems Approach, Frederic Mazenc, Michael Malisoff, Corina Barbalata, Zhong Ping Jiang

Faculty Publications

This paper presents a new design for the event-triggered output feedback control of uncertain linear time-varying systems. Departing from the traditional treatments of event-triggered linear time-invariant systems, it is shown that factoring of fundamental solutions as products of solutions of matrix differential equations, together with small-gain arguments and the notions of interval observers and positive systems, lead to a new class of robust event-triggered output-feedback controllers. A key innovation is our use of new event triggers, which use vectors of absolute values instead of the usual Euclidean 2-norms. An illustrative example of a curve tracking system from marine robotics validates …

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Riding The Wave: Reactive Vector-Borne Disease Policy Renders The United States Vulnerable To Outbreaks And Insecticide Resistance, Kyndall C. Dye-Braumuller, Jennifer R. Gordon, Kaci Mccoy, Danielle Johnson, Rhoel Dinglasan, Melissa Nolan Ph.D., Mph Mar 2022

Riding The Wave: Reactive Vector-Borne Disease Policy Renders The United States Vulnerable To Outbreaks And Insecticide Resistance, Kyndall C. Dye-Braumuller, Jennifer R. Gordon, Kaci Mccoy, Danielle Johnson, Rhoel Dinglasan, Melissa Nolan Ph.D., Mph

Faculty Publications

Funding for vector-borne disease surveillance, management, and research is cyclical and reactive in the United States. The subsequent effects have yielded gross inequities nationally that unintentionally support recurrent outbreaks. This policy forum is comprised of four primary subsections that collectively identify specific areas for improvement and offer innovative solutions to address national inadequacies in vector borne disease policy and infrastructure.

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Computational Based Investigation Of Lattice Cell Optimization Under Uniaxial Compression Load, Derek G. Spear, Jeremiah S. Lane, Anthony N. Palazotto, Ryan A. Kemnitz Mar 2022

Computational Based Investigation Of Lattice Cell Optimization Under Uniaxial Compression Load, Derek G. Spear, Jeremiah S. Lane, Anthony N. Palazotto, Ryan A. Kemnitz

Faculty Publications

Structural optimization is a methodology used to generate novel structures within a design space by finding a maximum or minimum point within a set of constraints. Topology optimization, as a subset of structural optimization, is often used as a means for light-weighting a structure while maintaining mechanical performance. This article presents the mathematical basis for topology optimization, focused primarily on the Bi-directional Evolutionary Structural Optimization (BESO) and Solid Isotropic Material with Penalization (SIMP) methodologies, then applying the SIMP methodology to a case study of additively manufactured lattice cells. Three lattice designs were used: the Diamond, I-WP, and Primitive cells. These …

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Thermo-Fluidic Transport Process In A Novel M-Shaped Cavity Packed With Non-Darcian Porous Medium And Hybrid Nanofluid: Application Of Artificial Neural Network (Ann), Dipak Kumar Mandal, Nirmalendu Biswas, Nirmal K. Manna, Dilip Kumar Gayen, Rama S. R. Gorla, Ali J. Chamkha Mar 2022

Thermo-Fluidic Transport Process In A Novel M-Shaped Cavity Packed With Non-Darcian Porous Medium And Hybrid Nanofluid: Application Of Artificial Neural Network (Ann), Dipak Kumar Mandal, Nirmalendu Biswas, Nirmal K. Manna, Dilip Kumar Gayen, Rama S. R. Gorla, Ali J. Chamkha

Faculty Publications

In this work, an attempt has been made to explore numerically the thermo-fluidic transport process in a novel M-shaped enclosure filled with permeable material along with Al2O3-Cu hybrid nanoparticles suspended in water under the influence of a horizontal magnetizing field. To exercise the influence of geometric parameters, a classical trapezoidal cavity is modified with an inverted triangle at the top to construct an M-shaped cavity. The cavity is heated isothermally from the bottom and cooled from the top, whereas the inclined sidewalls are insulated. The role of geometric parameters on the thermal performance is scrutinized thoroughly …

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Revisiting Proactive And Reactive Pathways To Resilience Among Cism-Trained Responders And General Population Participants: Mechanisms That Contribute To Building Overall Psychological Body Armortm, Harvey J. Burnett Jr., Justine Jaeger, Kristen R. Witzel, Karl G. D. Bailey Mar 2022

Revisiting Proactive And Reactive Pathways To Resilience Among Cism-Trained Responders And General Population Participants: Mechanisms That Contribute To Building Overall Psychological Body Armortm, Harvey J. Burnett Jr., Justine Jaeger, Kristen R. Witzel, Karl G. D. Bailey

Faculty Publications

Two previous studies by Burnett and colleagues found preliminary support for several innate well-being and behavioral variables that contribute to one’s Psychological Body Armor’sTM (PBA), which is comprised of two unique interacting pathways (proactive and reactive resilience) among trained disaster mental health responders and the general population. This study sought to improve, expand, and replicate the findings of these two studies. Data was collected from 509 Amazon Mechanical Turk workers and 343 trained novice and experienced disaster mental health crisis intervention responders, who were general members of the International Critical Incident Stress Foundation or the Michigan Crisis Response Association, eight …

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Initial Soil Conditions Outweigh Management In A Cool-Season Dairy Farm's Carbon Sequestration Potential, Kyle A. Arndt, Eleanor E. Campbell, Chris D. Dorich, A. Stuart Grandy, Timothy S. Griffin, Peter Ingraham, Apryl L. Perry, Ruth K. Varner, Alexandra R. Contosta Feb 2022

Initial Soil Conditions Outweigh Management In A Cool-Season Dairy Farm's Carbon Sequestration Potential, Kyle A. Arndt, Eleanor E. Campbell, Chris D. Dorich, A. Stuart Grandy, Timothy S. Griffin, Peter Ingraham, Apryl L. Perry, Ruth K. Varner, Alexandra R. Contosta

Faculty Publications

Pastures and rangelands are a dominant portion of global agricultural land and have the potential to sequester carbon (C) in soils, mitigating climate change. Management intensive grazing (MIG), or high density grazing with rotations through paddocks with long rest periods, has been highlighted as a method of enhancing soil C in pastures by increasing forage production. However, few studies have examined the soil C storage potential of pastures under MIG in the northeastern United States, where the dairy industry comprises a large portion of agricultural use and the regional agricultural economy. Here we present a 12-year study conducted in this …

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Neighborhood Deprivation And Risk Of Mortality Among Men With Prostate Cancer: Findings From A Long-Term Follow-Up Study, Madhav K.C., Ariane L. Rung, Edward J. Trapido, Laura S. Rozek, Elizabeth T.H. Fontham, Jeannette T. Bensen, Laura Farnan, Susan E. Steck Phd, Mph, Rd, Lixin Song, James L. Mohler, Edward S. Peters Feb 2022

Neighborhood Deprivation And Risk Of Mortality Among Men With Prostate Cancer: Findings From A Long-Term Follow-Up Study, Madhav K.C., Ariane L. Rung, Edward J. Trapido, Laura S. Rozek, Elizabeth T.H. Fontham, Jeannette T. Bensen, Laura Farnan, Susan E. Steck Phd, Mph, Rd, Lixin Song, James L. Mohler, Edward S. Peters

Faculty Publications

Background The overall survival rate of prostate cancer (PCa) has improved over the past decades. However, huge socioeconomic and racial disparities in overall and prostate cancer-specific mortality exist. The neighborhood-level factors including socioeconomic disadvantage and lack of access to care may contribute to disparities in cancer mortality. This study examines the impact of neighborhood deprivation on mortality among PCa survivors. Methods North Carolina–Louisiana Prostate Cancer Project (PCaP) data were used. A total of 2113 men, 1046 AA and 1067 EA, with PCa were included in the analysis. Neighborhood deprivation was measured by the Area Deprivation Index (ADI) at the census …

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Fourth-Order Comprehensive Adjoint Sensitivity Analysis Methodology For Nonlinear Systems (4th-Casam-N): Ii. Application To A Nonlinear Heat Conduction Paradigm Model, Dan Gabriel Cacuci Feb 2022

Fourth-Order Comprehensive Adjoint Sensitivity Analysis Methodology For Nonlinear Systems (4th-Casam-N): Ii. Application To A Nonlinear Heat Conduction Paradigm Model, Dan Gabriel Cacuci

Faculty Publications

This work illustrates the application of the fourth-order comprehensive sensitivity analysis methodology for nonlinear systems (abbreviated as “4th-CASAM-N”), which enables the efficient computation of exactly determined 1st-, 2nd-, 3rd-, and 4th-order functional derivatives of results produced by computational models with respect to the model’s parameters. Results produced by computational models are called model “responses” and the respective functional derivatives are called “sensitivities” (with respect) to model parameters. The qualifier “comprehensive” indicates that the 4th-CASAM-N methodology enables the exact and efficient computation not only of response sensitivities with respect to customary model parameters (including computational input data, correlations, initial and/or boundary …

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Fourth-Order Comprehensive Adjoint Sensitivity Analysis Methodology For Nonlinear Systems (4th-Casam-N): I. Mathematical Framework, Dan Gabriel Cacuci Feb 2022

Fourth-Order Comprehensive Adjoint Sensitivity Analysis Methodology For Nonlinear Systems (4th-Casam-N): I. Mathematical Framework, Dan Gabriel Cacuci

Faculty Publications

This work presents the fourth-order comprehensive sensitivity analysis methodology for nonlinear systems (abbreviated as “4th-CASAM-N”) for exactly and efficiently computing the first-, second-, third-, and fourth-order functional derivatives (customarily called “sensitivities”) of physical system responses (i.e., “system performance parameters”) to the system’s (or model) parameters. The qualifier “comprehensive” indicates that the 4th-CASAM-N methodology enables the exact and efficient computation not only of response sensitivities with respect to the customary model parameters (including computational input data, correlations, initial and/or boundary conditions) but also with respect to imprecisely known material boundaries, caused by manufacturing tolerances, of the system under consideration. The 4th-CASAM-N …

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Diet Quality Scores And Cardiometabolic Risk Factors In Mexican Children And Adolescents: A Longitudinal Analysis, Abeer Ali Aljahdali, Karen E. Peterson, Alejandra Cantoral, Edward Ruiz-Narvaez, Martha M. Tellez-Rojo, Hyungjin Myra Kim, James R. Hébert Scd, Michael David Wirth Msph, Phd, Face, Libni A. Torres-Olascoaga, Nitin Shivappa Mbbs, Mph, Ph.D., Ana Baylin Feb 2022

Diet Quality Scores And Cardiometabolic Risk Factors In Mexican Children And Adolescents: A Longitudinal Analysis, Abeer Ali Aljahdali, Karen E. Peterson, Alejandra Cantoral, Edward Ruiz-Narvaez, Martha M. Tellez-Rojo, Hyungjin Myra Kim, James R. Hébert Scd, Michael David Wirth Msph, Phd, Face, Libni A. Torres-Olascoaga, Nitin Shivappa Mbbs, Mph, Ph.D., Ana Baylin

Faculty Publications

There is limited evidence for the effects of diet on cardiometabolic profiles during the pubertal transition. We collected repeated measures of diet quality and cardiometabolic risk factors among Mexican youth. This analysis included 574 offspring of the Early Life Exposure in Mexico to Environmental Toxicants (ELEMENT) birth cohort followed up to three time points. Dietary Approaches to Stop Hypertension (DASH), alternate Mediterranean Diet (aMedDiet), and Children’s Dietary Inflammatory Index (C-DIITM) scores were computed from food frequency questionnaires. Higher DASH and aMedDiet scores reflect a higher diet quality, and lower C-DII scores reflect an anti-inflammatory diet. Cardiometabolic risk factors …

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Patients With Obesity And A History Of Metformin Treatment Have Lower Influenza Mortality: A Retrospective Cohort Study, Tammy H. Cummings, Joseph Magagnoli Ph.D., Ms, James W. Hardin, S. Scott Sutton Feb 2022

Patients With Obesity And A History Of Metformin Treatment Have Lower Influenza Mortality: A Retrospective Cohort Study, Tammy H. Cummings, Joseph Magagnoli Ph.D., Ms, James W. Hardin, S. Scott Sutton

Faculty Publications

Background: Obesity is a risk factor for the development of influenza by leading to a chronic inflammatory state and T-cell dysfunction. Based upon preclinical research, metformin has influenza activity by restoring T-cell function and improving the immune response. Objective: We aimed to evaluate the potential drug repurposing of metformin for the management of influenza among patients with obesity utilizing national claims data in an electronic health record database. Methods: The VA Informatics and Computing Infrastructure (VINCI) was utilized to obtain individual-level information on demographics, administrative claims, and pharmacy dispensation. A cohort was created among individuals with laboratory confirmed diagnosis of …

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Amorphization Of Pseudocapacitive T−Nb2O5 Accelerates Lithium Diffusivity As Revealed Using Tunable Isomorphic Architectures, Wessel Van Den Bergh, Sean Wechsler, Hasala Nadeesini Lokupitiya, Lauren Jarocha, Kwangnam Kim, James Chapman, Kyoung E. Kweon, Brandon C. Wood, Steve Heald, Morgan Stefik Phd Feb 2022

Amorphization Of Pseudocapacitive T−Nb2O5 Accelerates Lithium Diffusivity As Revealed Using Tunable Isomorphic Architectures, Wessel Van Den Bergh, Sean Wechsler, Hasala Nadeesini Lokupitiya, Lauren Jarocha, Kwangnam Kim, James Chapman, Kyoung E. Kweon, Brandon C. Wood, Steve Heald, Morgan Stefik Phd

Faculty Publications

Intercalationpseudocapacitancecan combinecapacitor-likepower densitieswith battery-likeenergy densities.Such surface-limitedbehaviorrequiresrapid diffusionwhere amorphizationcan increasesolid-statediffusivity.Here intercalationpseudoca-pacitivematerialswith tailoredextentsof amorphizationin T-Nb2O5are first reported.Amorphizationwas characterizedwithWAXS, XPS, XAFS, and EPR which suggesteda peroxide-rich(O22) surface that was consistentwith DFT predictions.A seriesof tunableisomorphicarchitecturesenabledcomparisonswhileindependentlyvaryingtransportparameters.Throughprocessof elimination,solid-statelithium diffusionwas identifiedas thedominantdiffusive-constraintdictatingthe maximumvoltagesweep rate for surface-limitedkinetics(vSLT), termed the Surface-LimitedThreshold(SLT). ThevSLTincreasedwith amorphizationhoweverstable cycling requiredcrystallineT-Nb2O5. A current-responsemodel using series-impedanceswell-matchedtheseobservations.This perspectiverevealedthat amorphizationof T-Nb2O5enhancedsolid-statediffusionby 12.2% and increasedsurface-limitationsby 17.0% (stablesamples).This approachenabledretaining95% lithiationcapacityat ~800mVs1(1,600C-rate equivalent).

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Microbial Feedbacks On Soil Organic Matter Dynamics Underlying The Legacy Effect Of Diversified Cropping Systems, Maria Mooshammer, A. Stuart Grandy, Francisco Calderon, Steve Culman, Bill Deen, Rhae A. Drijber, Kari Dunfield, Virginia L. Jin, R. Michael Lehman, Shannon L. Osborne, Marty Schmer, Timothy M. Bowles Feb 2022

Microbial Feedbacks On Soil Organic Matter Dynamics Underlying The Legacy Effect Of Diversified Cropping Systems, Maria Mooshammer, A. Stuart Grandy, Francisco Calderon, Steve Culman, Bill Deen, Rhae A. Drijber, Kari Dunfield, Virginia L. Jin, R. Michael Lehman, Shannon L. Osborne, Marty Schmer, Timothy M. Bowles

Faculty Publications

Crop rotations have well-known aboveground and belowground benefits. At regional to continental scales, the unifying mechanisms of how diversified rotations alter soil organic matter (SOM) dynamics have not been demonstrated. We assessed how increasing crop rotational diversity across a soil-climate gradient affected the integrated response of SOM chemistry, microbial community composition, and its enzymatic potential to degrade SOM. Agroecosystems with the same crop rotational diversity (all sampled during the corn phase) shared similarities in molecular SOM patterns with a strong microbial signature, pointing to common transformation processes. Differences in SOM chemistry between rotations were mainly characterized by shifts in microbial …

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Delaunay Walk For Fast Nearest Neighbor: Accelerating Correspondence Matching For Icp, James D. Anderson, Ryan M. Raettig, Joshua Larson, Clark N. Taylor, Thomas Wischgoll Feb 2022

Delaunay Walk For Fast Nearest Neighbor: Accelerating Correspondence Matching For Icp, James D. Anderson, Ryan M. Raettig, Joshua Larson, Clark N. Taylor, Thomas Wischgoll

Faculty Publications

Point set registration algorithms such as Iterative Closest Point (ICP) are commonly utilized in time-constrained environments like robotics. Finding the nearest neighbor of a point in a reference 3D point set is a common operation in ICP and frequently consumes at least 90% of the computation time. We introduce a novel approach to performing the distance-based nearest neighbor step based on Delaunay triangulation. This greedy algorithm finds the nearest neighbor of a query point by traversing the edges of the Delaunay triangulation created from a reference 3D point set. Our work integrates the Delaunay traversal into the correspondences search of …

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Phenanthrene: Establishing Lower And Upper Bounds To The Binding Energy Of A Very Weakly Bound Anion, Elisabeth Gruber, Siegfried Kollotzek, Stefan Bergmeister, Fabio Zappa, Milan Ončák, Paul Scheier, Olof E. Echt Feb 2022

Phenanthrene: Establishing Lower And Upper Bounds To The Binding Energy Of A Very Weakly Bound Anion, Elisabeth Gruber, Siegfried Kollotzek, Stefan Bergmeister, Fabio Zappa, Milan Ončák, Paul Scheier, Olof E. Echt

Faculty Publications

Quite a few molecules do not form stable anions that survive the time needed for their detection; their electron affinities (EA) are either very small or negative. How does one measure the EA if the anion cannot be observed? Or, at least, can one establish lower and upper bounds to their EA? We propose two approaches that provide lower and upper bounds. We choose the phenanthrene (Ph) molecule whose EA is controversial. Through competition between helium evaporation and electron detachment in HenPh- clusters, formed in helium nanodroplets, we estimate the lower bound of the vertical detachment energy …

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Utilization And Efficient Computation Of Polarization Factor Q For Fast, Accurate Brdf Modeling, Samuel D. Butler, Michael A. Marciniak Feb 2022

Utilization And Efficient Computation Of Polarization Factor Q For Fast, Accurate Brdf Modeling, Samuel D. Butler, Michael A. Marciniak

Faculty Publications

The Bidirectional Reflectance Distribution Function (BRDF) is of substantial use in remote sensing, scene generation, and computer graphics, to describe optical scatter off realistic surfaces. This paper begins by summarizing our prior work in relating wave optics and geometric optics models, culminating with the Modified Cook-Torrance (MCT) model. The MCT model is evaluated here against aluminum, Infragold, and silver paint at various wavelengths in the IR. In each case, the MCT model is shown to outperform a standard microfacet model. Then, this paper shows a non-trivial method of computing the primary new term, the polarization factor Q. This optimization …

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Multidimensional, High Precision Measurements Of Beam Single Spin Asymmetries In Semi-Inclusive Pi+ Electroproduction Off Protons In The Valence Region, S. Diehl, A. Kim, G. Angelini, K. Joo, S. Adhikari, M. Amaryan, M. Arratia, H. Atac, H. Avakian, C. Ayerbe Gayoso, N. A. Baltzell, L. Barion, S. Bastami, M. Battaglieri, I. Bedlinskiy, F. Benmokhtar, A. Bianconi, A. S. Biselli, M. Bondi, F. Bossù, Steffen Strauch, Et. Al. Feb 2022

Multidimensional, High Precision Measurements Of Beam Single Spin Asymmetries In Semi-Inclusive Pi+ Electroproduction Off Protons In The Valence Region, S. Diehl, A. Kim, G. Angelini, K. Joo, S. Adhikari, M. Amaryan, M. Arratia, H. Atac, H. Avakian, C. Ayerbe Gayoso, N. A. Baltzell, L. Barion, S. Bastami, M. Battaglieri, I. Bedlinskiy, F. Benmokhtar, A. Bianconi, A. S. Biselli, M. Bondi, F. Bossù, Steffen Strauch, Et. Al.

Faculty Publications

High precision measurements of the polarized electron beam-spin asymmetry in semi-inclusive deep inelastic scattering (SIDIS) from the proton have been performed using a 10.6 GeV incident electron beam and the CLAS12 spectrometer at Jefferson Lab. We report here a high precision multidimensional study of single πþ SIDIS data over a large kinematic range in Bjorken x, fractional energy, and transverse momentum of the hadron as well as photon virtualities Q2 ranging from 1–7 GeV2. In particular, the structure function ratio sinϕ LU/ FUU has been determined, where sinϕ LU is a twist-3 quantity that …

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Measurement Of The Nucleon F N2 / F P2 Tructure Function Ratio By The Jefferson Lab Marathon Tritium/Helium-3 Deep Inelastic Scattering Experiment, D. Abrams, H. Albataineh, B. S. Aljawrneh, S. Alsalmi, D. Androic, K. Aniol, W. Armstrong, J. Arrington, H. Atac, T. Averett, C. Ayerbe Gayoso, X. Bai, J. Bane, S. Barcus, A. Beck, V. Bellini, H. Bhatt, D. Bhetuwal, D. Biswas, D. Blyth, Roberto Petti, Et. Al. Feb 2022

Measurement Of The Nucleon F N2 / F P2 Tructure Function Ratio By The Jefferson Lab Marathon Tritium/Helium-3 Deep Inelastic Scattering Experiment, D. Abrams, H. Albataineh, B. S. Aljawrneh, S. Alsalmi, D. Androic, K. Aniol, W. Armstrong, J. Arrington, H. Atac, T. Averett, C. Ayerbe Gayoso, X. Bai, J. Bane, S. Barcus, A. Beck, V. Bellini, H. Bhatt, D. Bhetuwal, D. Biswas, D. Blyth, Roberto Petti, Et. Al.

Faculty Publications

The ratio of the nucleon F2 structure functions, F n2 / F p2 is determined by the MARATHON experiment from measurements of deep inelastic scattering of electrons from 3H and 3He nuclei. The experiment was performed in the Hall A Facility of Jefferson Lab using two high-resolution spectrometers for electron detection, and a cryogenic target system which included a low-activity tritium cell. The data analysis used a novel technique exploiting the mirror symmetry of the two nuclei, which essentially eliminates many theoretical uncertainties in the extraction of the ratio. The results, which cover the Bjorken …

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Diet Quality And Dietary Inflammatory Index Score Among Women’S Cancer Survivors, Sibylle Kranz, Faten Hasan, Erin Kennedy, Jamie Zoellner, Kristin A. Guertin, Nitin Shivappa Mbbs, Mph, Ph.D., James R. Hébert, Roger Anderson, Wendy Cohn Feb 2022

Diet Quality And Dietary Inflammatory Index Score Among Women’S Cancer Survivors, Sibylle Kranz, Faten Hasan, Erin Kennedy, Jamie Zoellner, Kristin A. Guertin, Nitin Shivappa Mbbs, Mph, Ph.D., James R. Hébert, Roger Anderson, Wendy Cohn

Faculty Publications

The purpose of this study was to investigate Healthy Eating Index 2015 (HEI-2015) and Energy-Adjusted Dietary Inflammatory Index (E-DIITM) scores in women's cancer survivors and to examine socio-economic (SES) characteristics associated with these two diet indices. In this cross-sectional study, survivors of women's cancers completed a demographic questionnaire and up to three 24-h dietary recalls. HEI-2015 and E-DII scores were calculated from average intakes. One-way ANOVA was used to examine the association of various demographic factors on HEI-2015 and E-DII scores. Pearson Correlation was used to calculate the correlation between the two scores. The average HEI-2015 score was 55.0 +/- …

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