Digital Commons Network^™

Modified Track Shoes And Their Effect On The Emg Activity Of Calf Muscles, Marlon Greensword, Fereydoun Aghazadeh, Saif Al-Qaisi

Faculty Publications

Although track and field spike shoes are crafted for runners, these shoes are not designed for regular walking. With such shoes, runners may eventually encounter serious chronic injuries such as plantar fasciitis, shin splints, achilles tendinitis, chondromalacia, and iliotibial band syndrome. To address this problem, a modified spike shoe was tested and compared to a regular spike shoe. The modification consists of adding a removable heel to the shoe sole in order to reduce the flexion of the foot and properly level the foot for walking. Nine healthy participants performed walking drills at 2 and 3 mph, using the original …

Handwheel Valve Operation: Assessment Of Four Opening Methods In Terms Of Muscle Loading, Perceived Comfort, And Efficiency, Fereydoun Aghazadeh, Saif Al Qaisi, Francis Hutchinson, Laura Ikuma

Faculty Publications

Injuries due to manual valve handwheel operations are a major concern in the chemical process industry. Manual valves are used to start, stop, and control flow in process lines. The torque required to operate handwheels after the initial "breaking" can vary due to the size, design, and condition of the valve. This study tested four methods of turning the handwheel on a medium-sized gate valve at two different torque requirements (25 Nm and 50 Nm). The methods were compared to each other, in terms of efficiency, subjective ratings of perceived exertion, and electromyography activity of the upper extremity and trunk …

State Of Charge And Loss Of Active Material Estimation Of A Lithium Ion Cell Under Low Earth Orbit Condition Using Kalman Filtering Approaches, Saeed Khaleghi Rahimian, Sean Rayman, Ralph E. White

Faculty Publications

The state of charge (SOC) and the loss of active material of the electrodes of a Li ion cell under Low Earth Orbit condition (LEO) have been estimated using Kalman filtering methods, by means of the physics-based single particle (SP) model. Zero mean Gaussian noise was added to the charge-discharge curves obtained by the SP model to generate synthetic data. Afterwards, nonlinear Filtering approaches including Extended Kalman Filtering (EKF) and Unscented Kalman Filtering (UKF) were applied to predict the true SOC and the electrodes’ degradation, by minimizing the measurement residuals between the model prediction and the synthetic data. The results …

Understanding Resistance To Standardization In Education: The Tragedy Of The Commons As A Theoretical Framework, Grinell Smith, Colette Rabin

Faculty Publications

The purpose of this paper is to articulate how a theory, developed in 1968 by Garrett Hardin to describe how shared resources, or “commons” can become depleted, also elucidates the mechanism by which standardization of educational outcomes and assessment have come to dominate current education discourse. We then present results of a case study of a school struggling to succeed within a context of a district’s hyper-focus on standardized measures of success, and employ the theory to illustrate its usefulness to explain what we found at the school site. We believe this theoretical framework provides interesting perspectives on current trends …

Ionically Self-Assembled, Multi-Luminophore One-Dimensional Micro- And Nanoscale Aggregates Of Thiacarbocyanine Gumbos, Sergio L. De Rooy, Susmita Das, Min Li, Bilal El-Zahab, Atiya Jordan, Ridgely Lodes, Anna Weber, Lin Chandler, Gary A. Baker, Isiah M. Warner

Faculty Publications

Groups of uniform materials based on organic salts (GUMBOS), derived from thiacarbocyanine (TC)-based dyes with increasing methyne chain lengths, were prepared through a single-step metathesis reaction between the iodide form of the TC dye and lithium bis(perfluoroethylsulfonyl)imide as the lipophilic anion source. Ionic self-assembly of these fluorescent hydrophobic GUMBOS resulted in aqueous dispersions of one-dimensional micro- and nanoscale molecular aggregates. Blended binary and ternary aggregates containing multiple TC GUMBOS were also prepared. These nanostructures exhibited a variety of aspect ratios, affording tunable Förster resonance energy transfer (FRET) and aggregation-dependent spectroscopic properties. © 2012 American Chemical Society.

Choral Intelligibility When Recording With An Orchestra: An Audio Engineer's Perspective, Michael F. Gates

Faculty Publications

From an audio engineer's perspective, producing a recording that features a choir and orchestra requires many careful considerations. It is reasonable to suggest that paramount to the final product is the intelligibility of the sung text. It is well known that the singer's formant, visible as a spectral peak around 3,000 Hz, assists a singer to be heard over an orchestra. Research indicates however that in choral singing this region is much lower in amplitude than in operatic singing. Because of many acoustic variables, the singing may well be masked and the text obscured. Critical listening analysis of recordings of …

Getting It Right The First Time: Predicted Performance Guarantees From The Analysis Of Emergent Behavior In Autonomous And Semi-Autonomous Systems, Ronald C. Arkin, Damian M. Lyons, Shu Jiang, Prem Nirmal, Munzir Zafar

Faculty Publications

A crucially important aspect for mission-critical robotic operations is ensuring as best as possible that an autonomous system be able to complete its task. In a project for the Defense Threat Reduction Agency (DTRA) we are developing methods to provide such guidance, specifically for counter-Weapons of Mass Destruction (C-WMD) missions. In this paper, we describe the scenarios under consideration, the performance measures and metrics being developed, and an outline of the mechanisms for providing performance guarantees.

The Ethical And Professional Risks Of Engaged Scholarship, Kathleen F. Mcconnell

Faculty Publications

The article reviews several books including "Save the World on Your Own Time," by Stanley Fish, "Challenging the Prison-Industrial Complex: Activism, Arts & Educational Alternatives," edited by Stephen John Hartnett, and "The Ethics and Politics of Speech: Communication and Rhetoric in the Twentieth Century," by Pat J. Gehrke.

International Trademark Protection And Global Public Health: A Just-Compensation Regime For Expropriations And Regulatory Takings, Sam F. Halabi

Faculty Publications

Lawmakers in developed and developing countries are expanding legal protections for trademarks – words, combinations of colors, signs, letters, numerals, figurative elements and designs meant to convey the origin and quality of firms’ goods or services. The purported rationales underlying trademark protection are promotion of competition and reduction of consumers’ information costs. Trademark law promotes competition by giving trademark holders an incentive to invest in the quality of goods or services and then associate that quality with a relatively easy-to-identify brand, mark or logo. The law punishes private actors who attempt to free-ride on the goodwill built by the trademark …

Associations Between Screen-Based Sedentary Behavior And Cardiovascular Disease Risk Factors In Korean Youth, Wonwoo Byun, Marsha Dowda, Russell R. Pate

Faculty Publications

The purposes of this study were to: 1) describe the patterns of screen-based sedentary behaviors, and 2) examine the association between screen-based sedentary behavior and cardiovascular disease (CVD) risk factors in representative Korean children and adolescents, aged 12 to 18 yr, in the Korean National Health and Nutrition Examination Survey. Screen-based sedentary behavior was measured using self-report questionnaires that included items for time spent watching TV and playing PC/video games. Physical activity was measured using items for frequency and duration of moderate-to-vigorous physical activity (MVPA). CVD risk factors such as body mass index (BMI), waist circumference, LDL cholesterol, HDL cholesterol, …

Graduate Business Education In Adventist Colleges And Universities: History And Challenges, Annetta M. Gibson, Robert Firth

Faculty Publications

No abstract provided.

Analysis Of A Kinetic Multi-Segment Foot Model. Part Ii: Kinetics And Clinical Implications, Dustin A. Bruening, Kevin M. Cooney, Frank L. Buczek

Faculty Publications

Kinematic multi-segment foot models have seen increased use in clinical and research settings, but the addition of kinetics has been limited and hampered by measurement limitations and modeling assumptions. In this second of two companion papers, we complete the presentation and analysis of a three segment kinetic foot model by incorporating kinetic parameters and calculating joint moments and powers. The model was tested on 17 pediatric subjects (ages 7–18 years) during normal gait. Ground reaction forces were measured using two adjacent force platforms, requiring targeted walking and the creation of two sub-models to analyze ankle, midtarsal, and 1st metatarsophalangeal joints. …

Tailoring Remedies To Spur Innovation, Sarah R. Wasserman Rajec

Faculty Publications

An emerging rule in the district courts—thus far endorsed by the United States Court of Appeals for the Federal Circuit—allows a victorious patent holder to receive a permanent injunction against an infringer if she is able to show that she has suffered a loss of market share due to the infringement. The larger the loss of market share the patent holder can prove, the more likely the court will issue an injunction. This “market share rule” is a response to the Supreme Court’s ruling in eBay Inc. v. MercExchange, L.L.C., exhorting lower courts to engage in equitable balancing before awarding …

Private Policing Of Environmental Performance: Does It Further Public Goals?, Sarah L. Stafford

Faculty Publications

Over the past two decades the role of private parties in the policing of environmental regulation has grown dramatically. In some cases the Environmental Protection Agency (EPA) has led this effort. In other situations, private parties have provided the impetus for new policing activities that are conducted independently from the EPA. Private policing can be beneficial when the increased involvement of the private sector either decreases the costs of achieving a particular level of environmental performance or increases environmental performance in a cost-effective manner. Private parties, however, could also divert regulated entities away from regulatory objectives. This Article explores the …

Trehalose Transporter From African Chironomid Larvae Improves Desiccation Tolerance Of Chinese Hamster Ovary Cells, Nilay Chakraborty, Michael A. Menze, Heidi Elmoazzen, Halong Vu, Martin L. Yarmush, Steven C. Hand, Mehmet Toner

Faculty Publications

Dry preservation has been explored as an energy-efficient alternative to cryopreservation, but the high sensitivity of mammalian cells to desiccation stress has been one of the major hurdles in storing cells in the desiccated state. An important strategy to reduce desiccation sensitivity involves use of the disaccharide trehalose. Trehalose is known to improve desiccation tolerance in mammalian cells when present on both sides of the cell membrane. Because trehalose is membrane impermeant the development of desiccation strategies involving this promising sugar is hindered. We explored the potential of using a high-capacity trehalose transporter (TRET1) from the African chironomid Polypedilum vanderplanki …

The Future Of Abandoned Big Box Stores : Legal Solutions To The Legacies Of Poor Planning Decisions, Sarah B. Schindler

Faculty Publications

Big box stores, the defining retail shopping location for the majority of American suburbs, are being abandoned at alarming rates, due in part to the economic downturn. These empty stores impose numerous negative externalities on the communities in which they are located, including blight, reduced property values, loss of tax revenue, environmental problems, and a decrease in social capital. While scholars have generated and critiqued prospective solutions to prevent abandonment of big box stores, this Article asserts that local zoning ordinances can alleviate the harms imposed by the thousands of existing, vacant big boxes. Because local governments control land use …

St. John's Wort Inhibits Insulin Signaling In Murine And Human Adipocytes, Allison J. Richard, Zhaleh J. Amini, David M. Ribnicky, Jacqueline M. Stephens

Faculty Publications

Adipocytes are insulin-sensitive cells that play a major role in energy homeostasis. Obesity is the primary disease of fat cells and a major risk factor for the development of Type 2 diabetes, cardiovascular disease, and metabolic syndrome. The use of botanicals in the treatment of metabolic diseases is an emerging area of research. In previous studies, we screened over 425 botanical extracts for their ability to modulate adipogenesis and insulin sensitivity. We identified St. John's Wort (SJW) extracts as inhibitors of adipogenesis of 3T3-L1 cells and demonstrated that these extracts also inhibited insulin-sensitive glucose uptake in mature fat cells. In …

Angiogenic Deficiency And Adipose Tissue Dysfunction Are Associated With Macrophage Malfunction In Sirt1 -/- Mice, Fen Xu, David Burk, Zhanguo Gao, Jun Yin, Xia Zhang, Jianping Weng, Jianping Ye

Faculty Publications

The histone deacetylase sirtuin 1 (SIRT1) inhibits adipocyte differentiation and suppresses inflammation by targeting the transcription factors peroxisome proliferator-activated receptor γ and nuclear factor κB. Although this suggests that adiposity and inflammation should be enhanced when SIRT1 activity is inactivated in the body, this hypothesis has not been tested in SIRT1 null (SIRT1 -/-) mice. In this study, we addressed this issue by investigating the adipose tissue in SIRT1 -/-mice. Compared with their wild-type littermates, SIRT1 null mice exhibited a significant reduction in body weight. In adipose tissue, the average size of adipocytes was smaller, the content of extracellular matrix …

Plant Science In Forest Canopies - The First 30 Years Of Advances And Challenges (1980-2010), Margaret D. Lowman, Timothy D. Schowalter

Faculty Publications

Contents: Summary 12 I. Introduction 12 II. History of canopy access 13 III. Consequences of whole-tree approaches to forest science 15 IV. Canopy communities - their inhabitants, environment, and processes 16 V. The role of forest canopies in providing ecosystem services 21 VI. Using canopy science as a 'hook' to inspire forest conservation 21 VII. Conclusions -'black boxes' in canopy science that remain 22 Acknowledgements 23 References 24 Summary: As an emerging subdiscipline of forest biology, canopy science has undergone a transition from observational, 'oh-wow' exploration to a more hypothesis-driven, experimental arena for rigorous field biology. Although efforts to explore …

Ultraconserved Elements Are Novel Phylogenomic Markers That Resolve Placental Mammal Phylogeny When Combined With Species-Tree Analysis, John E. Mccormack, Brant C. Faircloth, Nicholas G. Crawford, Patricia Adair Gowaty, Robb T. Brumfield, Travis C. Glenn

Faculty Publications

Phylogenomics offers the potential to fully resolve the Tree of Life, but increasing genomic coverage also reveals conflicting evolutionary histories among genes, demanding new analytical strategies for elucidating a single history of life. Here, we outline a phylogenomic approach using a novel class of phylogenetic markers derived from ultraconserved elements and flanking DNA. Using species-tree analysis that accounts for discord among hundreds of independent loci, we show that this class of marker is useful for recovering deep-level phylogeny in placental mammals. In broad outline, our phylogeny agrees with recent phylogenomic studies of mammals, including several formerly controversial relationships. Our results …

Genomic Insights Into Adaptation To High-Altitude Environments, Z. A. Cheviron, R. T. Brumfield

Faculty Publications

Elucidating the molecular genetic basis of adaptive traits is a central goal of evolutionary genetics. The cold, hypoxic conditions of high-altitude habitats impose severe metabolic demands on endothermic vertebrates, and understanding how high-altitude endotherms cope with the combined effects of hypoxia and cold can provide important insights into the process of adaptive evolution. The physiological responses to high-altitude stress have been the subject of over a century of research, and recent advances in genomic technologies have opened up exciting opportunities to explore the molecular genetic basis of adaptive physiological traits. Here, we review recent literature on the use of genomic …

Telomere Maintenance Genes Sirt1 And Xrcc6 Impact Age-Related Decline In Telomere Length But Only Sirt1 Is Associated With Human Longevity, Sangkyu Kim, Xiuhua Bi, Malwina Czarny-Ratajczak, Jianliang Dai, David A. Welsh, Leann Myers, Michael A. Welsch, Katie E. Cherry, Jonathan Arnold, Leonard W. Poon, Michal Jazwinski

Faculty Publications

Leukocyte telomere length is widely considered a biomarker of human age and in many studies indicative of health or disease. We have obtained quantitative estimates of telomere length from blood leukocytes in a population sample, confirming results of previous studies that telomere length significantly decreases with age. Telomere length was also positively associated with several measures of healthy aging, but this relationship was dependent on age. We screened two genes known to be involved in telomere maintenance for association with the age-related decline in telomere length observed in our population to identify candidate longevity-associated genes. A single-nucleotide polymorphism located in …

A (Modest) Separation Of Powers Success Story, Tara Leigh Grove

Faculty Publications

No abstract provided.

Role Of Raltegravir In Hiv-1 Management, Kristina E. Rokas, P Brandon Bookstaver, Caitlin L. Shamroe, S Scott Sutton, Vanessa E. Millisor, Jacquelyn E. Bryant, Sharon B. Weissman

Faculty Publications

OBJECTIVE: To review the literature concerning the role of raltegravir in the treatment of HIV-1 in antiretroviral (ARV)-experienced and ARV-naïve patients. DATA SOURCES: A PubMed search was conducted for published data through March 2012 using the search terms raltegravir, MK-0518, and integrase strand transfer inhibitor. An additional search of International Pharmaceutical Abstracts for unpublished data, including data from the Infectious Diseases Society of America, the Conference on Retroviruses and Opportunistic Infections, the International AIDS Society, and the Interscience Conference on Antimicrobial Agents and Chemotherapy, was conducted using similar search terms. STUDY SELECTION AND DATA EXTRACTION: In vitro and in vivo …

What's Love Got To Do With It: Securing Access To Justice For Teens, Lisa V. Martin

Faculty Publications

During the past 15 years, researchers have documented the pervasiveness, severity, and lasting impact of dating violence on American adolescents. Studies also have shown teens to be firmly resistant to disclosing abuse to adults. Nonetheless, civil protection orders - the civil legal remedy most commonly relied upon to redress intimate partner violence in adult relationships - often remain inaccessible to abused teens. State protection order statutes exclude teens from their protections by restricting rights to standing by age and the relationship between the parties. When states grant teens standing, they often deter teens from pursuing the protections extended to them …

Note: Aimed At Protecting Ethnic Groups Or Women? A Look At Forced Pregnancy Under The Rome Statute, Alyson M. Drake

Faculty Publications

No abstract provided.

The Future Of Nursing: How Important Is Discipline-Specific Knowledge? A Conversation With Jacqueline Fawcett, Janie B. Butts, Karen L. Rich, Jacqueline Fawcett

Faculty Publications

Nurses have long attempted to secure a unique identity for the profession. Many scholars are now promoting an interdisciplinary framework for nursing practice. Fawcett is convinced that interdisciplinary practice poses a danger for nursing to lose its identity and that interdisciplinary practice cannot be successful if members of each discipline do not understand the conceptual models, practice, and research of their own discipline. Dr. Janie Butts and Dr. Karen Rich interviewed Dr. Jacqueline Fawcett about her views related to discipline-specific knowledge and nursing's future. The authors conclude that Fawcett's scientific foundation gives nursing the solidarity and power necessary to determine …

Clustering Of Unhealthy Behaviors In The Aerobics Center Longitudinal Study, Mariane Héroux, Ian Janssen, Duck-Chul Lee, Xuemei Sui, James R. Hébert, Steven N. Blair

Faculty Publications

Background

Objectives

Methods

Longitudinal Changes In Body Composition Associated With Healthy Ageing: Men, Aged 20-96 Years, Andrew S. Jackson, Ian Janssen, Xuemei Sui, Timothy S. Church, Steven N. Blair

Faculty Publications

Obesity and sarcopenia are health problems associated with ageing. The present study modelled the longitudinal changes in body composition of healthy men, aged from 20 to 96 years, and evaluated the fidelity of BMI to identify age-dependent changes in fat mass and fat-free mass. The data from 7265 men with multiple body composition determinations (total observations 38,328) were used to model the age-related changes in body mass, fat mass, fat-free mass, BMI and percentage of body fat. Changes in fat mass and fat-free mass were used to evaluate the fidelity of BMI and to detect body composition changes with ageing. …

The Effects Of Video Formats In Online News: A Study Of Recall And Stickiness, August Grant, Diane Guerrazzi, Jack Karlis

Faculty Publications

News organizations putting content on their websites may better engage their audience by offering a choice of raw video rather than packages. A two-by-three experiment studied the relationships among video format, time spent, and recall for online news. Test subjects viewed a traditional, broadcast-type standard news “package,” a disassembled package, and raw video with text. Results showed users spent significantly more time with the raw video format than with the other two formats. Time spent was strongly correlated with post-test recall of elements of each story, but there was no direct relationship between format and recall. A model is proposed …